Henry Brem, MD - Publications

Affiliations: 
1999- Neurosurgery Johns Hopkins University, Baltimore, MD 

214 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Khalafallah AM, Jimenez AE, Romo CG, Kamson DO, Kleinberg L, Weingart J, Brem H, Grossman SA, Mukherjee D. Quantifying the utility of a multidisciplinary neuro-oncology tumor board. Journal of Neurosurgery. 1-6. PMID 32947258 DOI: 10.3171/2020.5.Jns201299  0.37
2020 Khalafallah AM, Huq S, Jimenez AE, Brem H, Mukherjee D. The 5-factor modified frailty index: an effective predictor of mortality in brain tumor patients. Journal of Neurosurgery. 1-9. PMID 32796147 DOI: 10.3171/2020.5.Jns20766  0.342
2020 Huq S, Casaos J, Serra R, Peters M, Xia Y, Ding AS, Ehresman J, Kedda JN, Morales M, Gorelick NL, Zhao T, Ishida W, Perdomo-Pantoja A, Cecia A, Ji C, ... ... Brem H, et al. Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma. Molecular Cancer Therapeutics. PMID 32606016 DOI: 10.1158/1535-7163.Mct-19-0572  0.325
2020 Jackson C, Choi J, Khalafallah AM, Price C, Bettegowda C, Lim M, Gallia G, Weingart J, Brem H, Mukherjee D. A systematic review and meta-analysis of supratotal versus gross total resection for glioblastoma. Journal of Neuro-Oncology. PMID 32562247 DOI: 10.1007/S11060-020-03556-Y  0.362
2020 El Demerdash N, Kedda J, Ram N, Brem H, Tyler B. Novel therapeutics for brain tumors: current practice and future prospects. Expert Opinion On Drug Delivery. 17: 9-21. PMID 31971041 DOI: 10.1080/17425247.2019.1676227  0.408
2019 Han D, Serra R, Gorelick N, Fatima U, Eberhart CG, Brem H, Tyler B, Steckl AJ. Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor. Scientific Reports. 9: 17936. PMID 31784666 DOI: 10.1038/S41598-019-54283-Y  0.404
2019 Choi J, Rui Y, Kim J, Gorelick N, Wilson DR, Kozielski K, Mangraviti A, Sankey E, Brem H, Tyler B, Green JJ, Jackson EM. Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies. Nanomedicine : Nanotechnology, Biology, and Medicine. 102115. PMID 31655205 DOI: 10.1016/J.Nano.2019.102115  0.374
2019 Smith SJ, Tyler B, Gould TWA, Veal GJ, Gorelick NL, Rowlinson J, Serra R, Ritchie AA, Berry P, Otto A, Choi J, Skuli N, Estevez-Cebrero MA, Shakesheff KM, Brem H, et al. Overall survival in malignant glioma is significantly prolonged by neurosurgical delivery of etoposide and temozolomide from a thermo-responsive biodegradable paste. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31113843 DOI: 10.1158/1078-0432.Ccr-18-3850  0.384
2019 Wu A, Maxwell R, Xia Y, Cardarelli P, Oyasu M, Belcaid Z, Kim E, Hung A, Luksik AS, Garzon-Muvdi T, Jackson CM, Mathios D, Theodros D, Cogswell J, Brem H, et al. Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment. Journal of Neuro-Oncology. PMID 31025274 DOI: 10.1007/S11060-019-03172-5  0.32
2019 Ehresman JS, Garzon-Muvdi T, Rogers D, Lim M, Gallia GL, Weingart J, Brem H, Bettegowda C, Chaichana KL. Risk of Developing Postoperative Deficits Based on Tumor Location after Surgical Resection of an Intracranial Meningioma. Journal of Neurological Surgery. Part B, Skull Base. 80: 59-66. PMID 30733902 DOI: 10.1055/S-0038-1667066  0.335
2019 Huq S, Casaos J, Peters M, Xia Y, Ding A, Morales M, Gorelick N, Serra R, Zhao T, Ishida W, Perdomo-Pantoja A, Cecia A, Ji C, Suk I, Sidransky D, ... ... Brem H, et al. Abstract B06: Repositioning the FDA-approved antiviral drug ribavirin as targeted therapy for nasopharyngeal carcinoma Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-B06  0.347
2019 Serra R, Smith SJ, Rowlinson J, Gorelick NL, Veal GJ, Shakesheff K, Grundy R, Brem H, Rahman R, Tyler B. Local Delivery of the Poly-ADP-Ribose-Polymerase-Inhibitor Olaparib From a Biodegradable Paste Potentiates Radiotherapy and Prolongs Survival Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_641  0.321
2019 Rahman R, Campbell E, Brem H, Pearl M, Green J, Janowski M, Walczak P, Tyler B, Warren K, Singleton W, Mullen A, Boyd M, Veal G, Hargrave D, van Vuurden D, et al. SCIDOT-08. CHILDREN’S BRAIN TUMOUR DRUG DELIVERY CONSORTIUM (CBTDDC) Neuro-Oncology. 21: vi274-vi274. DOI: 10.1093/Neuonc/Noz175.1149  0.306
2019 Smith S, Serra R, Rowlinson J, Gorelick N, Veal G, Shakesheff K, Brem H, Grundy R, Tyler B, Rahman R. P11.60 Neurosurgical delivery of the poly ADP ribose polymerase-1 inhibitor olaparib from a thermo-responsive biodegradable paste potentiates radiotherapy and prolongs survival Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz126.206  0.312
2018 Nicholas SE, Salvatori R, Quinones-Hinojosa A, Redmond K, Gallia G, Lim M, Rigamonti D, Brem H, Kleinberg L. Deferred Radiotherapy After Debulking of Non-functioning Pituitary Macroadenomas: Clinical Outcomes. Frontiers in Oncology. 8: 660. PMID 30687636 DOI: 10.3389/Fonc.2018.00660  0.371
2018 Shapira-Furman T, Serra R, Gorelick N, Doglioli M, Tagliaferri V, Cecia A, Peters M, Kumar A, Rottenberg Y, Langer R, Brem H, Tyler B, Domb AJ. Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 295: 93-101. PMID 30605703 DOI: 10.1016/J.Jconrel.2018.12.048  0.392
2018 Maxwell R, Luksik AS, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Choi J, Theodros D, Jackson CM, Mathios D, Ye X, Tran PT, ... ... Brem H, et al. Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system. Oncoimmunology. 7: e1500108. PMID 30524891 DOI: 10.1080/2162402X.2018.1500108  0.315
2018 Harris-Bookman S, Mathios D, Martin AM, Xia Y, Kim E, Xu H, Belcaid Z, Polanczyk M, Barberi T, Theodros D, Kim J, Taube JM, Burger PC, Selby M, Taitt C, ... ... Brem H, et al. Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma. International Journal of Cancer. PMID 30248181 DOI: 10.1002/Ijc.31661  0.31
2018 Hung AL, Maxwell R, Theodros D, Belcaid Z, Mathios D, Luksik AS, Kim E, Wu A, Xia Y, Garzon-Muvdi T, Jackson C, Ye X, Tyler B, Selby M, Korman A, ... ... Brem H, et al. TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM. Oncoimmunology. 7: e1466769. PMID 30221069 DOI: 10.1080/2162402X.2018.1466769  0.364
2018 Paldor I, Chaichana KL, Brem H, Tyler BM. Targeted Local Therapy for Management of Intracranial High-Grade Gliomas. Progress in Neurological Surgery. 32: 159-171. PMID 29990982 DOI: 10.1159/000469688  0.397
2018 Casaos J, Huq S, Lott T, Felder R, Choi J, Gorelick N, Peters M, Xia Y, Maxwell R, Zhao T, Ji C, Simon T, Sesen J, Scotland SJ, Kast RE, ... ... Brem H, et al. Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors. Oncotarget. 9: 8054-8067. PMID 29487714 DOI: 10.18632/Oncotarget.23883  0.391
2018 Wu A, Cardarelli P, Oyasu M, Menezes D, Ponath P, Cogswell J, Maxwell R, Luksik A, Hung A, Kim E, Belcaid Z, Brem H, Pardoll D, Lim M. Abstract 1736: The combination of CXCR4 and checkpoint receptor inhibition improves survival in an orthotopic murine glioma model Cancer Research. 78: 1736-1736. DOI: 10.1158/1538-7445.Am2018-1736  0.36
2018 Maxwell R, Luksik A, Garzon-Muvdi T, Hung AL, Kim ES, Wu A, Xia Y, Belcaid Z, Gorelick N, Theodros D, Jackson C, Ye X, Tran PT, Redmond KJ, Brem H, et al. Impact of Corticosteroids on the Efficacy of Anti-PD-1 Therapy for Tumors Located Within or Outside the Central Nervous System International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.035  0.307
2017 Nabors LB, Portnow J, Ammirati M, Baehring J, Brem H, Butowski N, Fenstermaker RA, Forsyth P, Hattangadi-Gluth J, Holdhoff M, Howard S, Junck L, Kaley T, Kumthekar P, Loeffler JS, et al. NCCN Guidelines Insights: Central Nervous System Cancers, Version 1.2017. Journal of the National Comprehensive Cancer Network : Jnccn. 15: 1331-1345. PMID 29118226 DOI: 10.6004/Jnccn.2017.0166  0.305
2017 Mangraviti A, Raghavan T, Volpin F, Skuli N, Gullotti D, Zhou J, Asnaghi L, Sankey E, Liu A, Wang Y, Lee DH, Gorelick N, Serra R, Peters M, Schriefer D, ... ... Brem H, et al. HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy. Scientific Reports. 7: 14978. PMID 29097800 DOI: 10.1038/S41598-017-14990-W  0.379
2017 Ehresman JS, Garzon-Muvdi T, Rogers D, Lim M, Gallia GL, Weingart J, Brem H, Bettegowda C, Chaichana KL. The relevance of Simpson grade resectionsin the modern neurosurgical treatment of World Health Organization Grade 1, 2, and 3meningiomas. World Neurosurgery. PMID 29042332 DOI: 10.1016/j.wneu.2017.10.028  0.316
2017 Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM. The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma. Journal of Neuro-Oncology. PMID 28735458 DOI: 10.1007/S11060-017-2567-9  0.34
2017 Wu A, Weingart JD, Gallia GL, Lim M, Brem H, Bettegowda C, Chaichana KL. Risk Factors for Preoperative Seizures and Loss of Seizure Control in Patients Undergoing Surgery for Metastatic Brain Tumors. World Neurosurgery. PMID 28512046 DOI: 10.1016/J.Wneu.2017.05.028  0.346
2017 Garzon-Muvdi T, Yang W, Lim M, Brem H, Huang J. Atypical and anaplastic meningioma: outcomes in a population based study. Journal of Neuro-Oncology. PMID 28429237 DOI: 10.1007/S11060-017-2436-6  0.383
2017 Zhang C, Nance EA, Mastorakos P, Chisholm J, Berry S, Eberhart C, Tyler B, Brem H, Suk JS, Hanes J. Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28279797 DOI: 10.1016/J.Jconrel.2017.03.007  0.393
2017 Kessler RA, Garzon-Muvdi T, Yang W, Weingart J, Olivi A, Huang J, Brem H, Lim M. Metastatic Atypical and Anaplastic Meningioma: A Case Series and Review of the Literature. World Neurosurgery. PMID 28143726 DOI: 10.1016/J.Wneu.2017.01.070  0.319
2017 Smith S, Gould T, Tyler B, Ritchie A, Veal G, Shakesheff K, Brem H, Grundy R, Rahman R. Surg-24. Overall Survival In A Syngeneic Rodent Orthotopic High-Grade Glioma Model Is Significantly Prolonged By Neurosurgical Delivery Of Plga/Peg Interstitial Chemotherapy Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.979  0.342
2017 Smith S, Tyler B, Gould T, Veal G, Ritchie A, Berry P, Otto A, Rowlinson J, Choi J, Skuli N, Shakesheff K, Brem H, Grundy R, Rahman R. Scdt-10. Overall Survival In An Orthotopic Malignant Glioma Model Is Significantly Prolonged By Neurosurgical Delivery Of Plga/Peg Interstitial Chemotherapy Paste Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.1093  0.348
2017 Smith S, Gould T, Tyler B, Veal G, Ritchie A, Gorelick N, Choi J, Skuli N, Shakesheff K, Brem H, Grundy R, Rahman R. Trth-21. Glioma Survival Benefits From Neurosurgical Delivery Of Plga/Peg Interstitial Therapy Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox083.232  0.327
2017 Rahman R, Grundy R, Campbell E, Brem H, Pearl M, Green J, Janoski M, Cohen K, Walczak P, Warren K, Lowis S, Mullen A, Boyd M, Veal G, Hargrave D, et al. Children's brain tumour drug delivery consortium Neuro-Oncology. 19: 0. DOI: 10.1093/Neuonc/Nox083.218  0.308
2016 Mathios D, Kim JE, Mangraviti A, Phallen J, Park CK, Jackson CM, Garzon-Muvdi T, Kim E, Theodros D, Polanczyk M, Martin AM, Suk I, Ye X, Tyler B, Bettegowda C, ... Brem H, et al. Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM. Science Translational Medicine. 8: 370ra180. PMID 28003545 DOI: 10.1126/Scitranslmed.Aag2942  0.339
2016 Volpin F, Casaos J, Sesen J, Mangraviti A, Choi J, Gorelick N, Frikeche J, Lott T, Felder R, Scotland SJ, Eisinger-Mathason TS, Brem H, Tyler B, Skuli N. Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic. Oncogene. PMID 27941882 DOI: 10.1038/Onc.2016.457  0.391
2016 Mangraviti A, Tzeng SY, Gullotti D, Kozielski KL, Kim JE, Seng M, Abbadi S, Schiapparelli P, Sarabia-Estrada R, Vescovi A, Brem H, Olivi A, Tyler B, Green JJ, Quinones-Hinojosa A. Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival. Biomaterials. 100: 53-66. PMID 27240162 DOI: 10.1016/J.Biomaterials.2016.05.025  0.377
2016 Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM, Lim M, Weingart JD, Quinones-Hinojosa A, Bettegowda C, Kassam AB, Olivi A, Brem H, Riggins GJ, Gallia GL. Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines. Plos One. 11: e0150271. PMID 27028405 DOI: 10.1371/Journal.Pone.0150271  0.301
2016 Mangraviti A, Gullotti D, Tyler B, Brem H. Nanobiotechnology-based delivery strategies: New frontiers in brain tumor targeted therapies. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27016141 DOI: 10.1016/J.Jconrel.2016.03.031  0.404
2016 Upadhyay UM, Tyler B, Patta Y, Wicks R, Spencer K, Scott A, Masi B, Hwang L, Grossman R, Cima M, Brem H, Langer R. Correction: Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 45 (16071-16076) DOI: 10.1073/pnas.1313420110) Proceedings of the National Academy of Sciences of the United States of America. 113: E1327. DOI: 10.1073/Pnas.1600771113  0.303
2015 Jackson S, Anders NM, Mangraviti A, Wanjiku TM, Sankey EW, Liu A, Brem H, Tyler B, Rudek MA, Grossman SA. The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain. Journal of Neuro-Oncology. PMID 26626489 DOI: 10.1007/S11060-015-1998-4  0.327
2015 De la Garza-Ramos R, Kerezoudis P, Tamargo RJ, Brem H, Huang J, Bydon M. Surgical complications following malignant brain tumor surgery: An analysis of 2002-2011 data. Clinical Neurology and Neurosurgery. 140: 6-10. PMID 26615463 DOI: 10.1016/J.Clineuro.2015.11.005  0.355
2015 Jackson CM, Kochel CM, Nirschl CJ, Durham NM, Ruzevick J, Alme A, Francica BJ, Elias J, Daniels A, Dubensky TW, Lauer P, Brockstedt D, Baxi EG, Calabresi PA, Taube JM, ... ... Brem H, et al. Systemic Tolerance Mediated by Melanoma Brain Tumors is Reversible by Radiotherapy and Vaccination. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26490306 DOI: 10.1158/1078-0432.Ccr-15-1516  0.351
2015 Nabors LB, Portnow J, Ammirati M, Baehring J, Brem H, Brown P, Butowski N, Chamberlain MC, Fenstermaker RA, Friedman A, Gilbert MR, Hattangadi-Gluth J, Holdhoff M, Junck L, Kaley T, et al. Central Nervous System Cancers, Version 1.2015. Journal of the National Comprehensive Cancer Network : Jnccn. 13: 1191-202. PMID 26483059 DOI: 10.6004/Jnccn.2015.0148  0.335
2015 Grossman R, Burger P, Soudry E, Tyler B, Chaichana KL, Weingart J, Olivi A, Gallia GL, Sidransky D, Quiñones-Hinojosa A, Ye X, Brem H. MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 26249244 DOI: 10.1016/J.Jocn.2015.07.003  0.302
2015 Wang Y, Springer S, Zhang M, McMahon KW, Kinde I, Dobbyn L, Ptak J, Brem H, Chaichana K, Gallia GL, Gokaslan ZL, Groves ML, Jallo GI, Lim M, Olivi A, et al. Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195750 DOI: 10.1073/Pnas.1511694112  0.351
2015 Sesen J, Dahan P, Scotland SJ, Saland E, Dang VT, Lemarié A, Tyler BM, Brem H, Toulas C, Cohen-Jonathan Moyal E, Sarry JE, Skuli N. Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response. Plos One. 10: e0123721. PMID 25867026 DOI: 10.1371/Journal.Pone.0123721  0.37
2015 Chaichana KL, Pinheiro L, Brem H. Delivery of local therapeutics to the brain: working toward advancing treatment for malignant gliomas. Therapeutic Delivery. 6: 353-69. PMID 25853310 DOI: 10.4155/Tde.14.114  0.407
2015 Zhang F, Mastorakos P, Mishra MK, Mangraviti A, Hwang L, Zhou J, Hanes J, Brem H, Olivi A, Tyler B, Kannan RM. Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers. Biomaterials. 52: 507-16. PMID 25818456 DOI: 10.1016/J.Biomaterials.2015.02.053  0.396
2015 Mangraviti A, Tyler B, Brem H. Interstitial chemotherapy for malignant glioma: Future prospects in the era of multimodal therapy. Surgical Neurology International. 6: S78-84. PMID 25722936 DOI: 10.4103/2152-7806.151345  0.419
2015 Mangraviti A, Tzeng SY, Kozielski KL, Wang Y, Jin Y, Gullotti D, Pedone M, Buaron N, Liu A, Wilson DR, Hansen SK, Rodriguez FJ, Gao GD, DiMeco F, Brem H, et al. Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo. Acs Nano. 9: 1236-49. PMID 25643235 DOI: 10.1021/Nn504905Q  0.341
2015 Wicks RT, Azadi J, Mangraviti A, Zhang I, Hwang L, Joshi A, Bow H, Hutt-Cabezas M, Martin KL, Rudek MA, Zhao M, Brem H, Tyler BM. Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma. Neuro-Oncology. 17: 70-80. PMID 25053853 DOI: 10.1093/Neuonc/Nou143  0.313
2015 Jackson S, Anders N, Mangraviti A, Wanjiku T, Brem H, Tyler B, Rudek MA, Grossman SA. The effect of regadenoson-induced transient disruption of the blood brain barrier on temozolomide delivery to rat brain parenchyma. Journal of Clinical Oncology. 33: 2066-2066. DOI: 10.1200/Jco.2015.33.15_Suppl.2066  0.345
2015 Mathios D, Kim J, Phallen J, Mangraviti A, Park C, Theodros D, Jackson C, Garzon-Muvdi T, Kim E, Ye X, Tyler B, Brem H, Pardoll D, Lim M. Optimizing the delivery of chemotherapy in the setting of immunotherapy in a preclinical glioblastoma model Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P307  0.332
2015 Mathios D, Hwang T, Phallen J, Bettewgoda C, Ha P, Burger P, Brem H, McDonald K, Park C, Lim M. Abstract 3839: Investigation of epigenetic based inter-tumoral heterogeneity identifies novel ZMIZ1 gene as a biomarker of cancer patient survival in multiple tumor types Cancer Research. 75: 3839-3839. DOI: 10.1158/1538-7445.Am2015-3839  0.368
2015 Mangraviti A, Tzeng S, Gullotti D, Kozielski K, Kim J, Seng M, Abbadi S, Schiapparelli P, Sarabia-Estrada R, Brem H, Tyler B, Olivi A, Green J, Quinones-Hinojosa A. ATPS-90EFFICACY OF NON-VIRAL ENGINEERED ADIPOSE MESENCHYMAL STEM CELLS FOR BRAIN TUMOR THERAPY Neuro-Oncology. 17: v38.2-v38. DOI: 10.1093/Neuonc/Nov204.90  0.381
2015 Mangraviti A, Raghavan T, Volpin F, Skuli N, Zhou J, Eberhart C, Rodriguez F, Sankey E, Gullotti D, Liu A, Wang Y, Schriefer D, Brem H, Olivi A, Tyler B. ATPS-89LOCAL DELIVERY OF A SMALL-MOLECULE INHIBITOR OF HYPOXIA INDUCIBLE FACTOR-1: A NEW CANDIDATE DRUG FOR BRAIN TUMOR THERAPY Neuro-Oncology. 17: v38.1-v38. DOI: 10.1093/Neuonc/Nov204.89  0.445
2015 Jackson S, Anders N, Mangraviti A, Brem H, Tyler B, Rudek M, Grossman S. Tr-09The Effect Of Regadenoson-Induced Transient Disruption Of The Blood Brain Barrier On Temozolomide Delivery To Rat Brain Parenchyma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.154  0.339
2014 Bydon M, Abt NB, Macki M, Brem H, Huang J, Bydon A, Tamargo RJ. Preoperative anemia increases postoperative morbidity in elective cranial neurosurgery. Surgical Neurology International. 5: 156. PMID 25422784 DOI: 10.4103/2152-7806.143754  0.305
2014 Nabors LB, Portnow J, Ammirati M, Brem H, Brown P, Butowski N, Chamberlain MC, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hattangadi-Gluth J, Hesser D, Holdhoff M, Junck L, et al. Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines. Journal of the National Comprehensive Cancer Network : Jnccn. 12: 1517-23. PMID 25361798 DOI: 10.6004/Jnccn.2014.0151  0.345
2014 Upadhyay UM, Tyler B, Patta Y, Wicks R, Spencer K, Scott A, Masi B, Hwang L, Grossman R, Cima M, Brem H, Langer R. Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. Proceedings of the National Academy of Sciences of the United States of America. 111: 16071-6. PMID 25349381 DOI: 10.1073/Pnas.1313420110  0.411
2014 Woodworth GF, Dunn GP, Nance EA, Hanes J, Brem H. Emerging insights into barriers to effective brain tumor therapeutics. Frontiers in Oncology. 4: 126. PMID 25101239 DOI: 10.3389/Fonc.2014.00126  0.412
2014 Belcaid Z, Phallen JA, Zeng J, See AP, Mathios D, Gottschalk C, Nicholas S, Kellett M, Ruzevick J, Jackson C, Albesiano E, Durham NM, Ye X, Tran PT, Tyler B, ... ... Brem H, et al. Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. Plos One. 9: e101764. PMID 25013914 DOI: 10.1371/Journal.Pone.0101764  0.34
2014 Gabikian P, Tyler BM, Zhang I, Li KW, Brem H, Walter KA. Radiosensitization of malignant gliomas following intracranial delivery of paclitaxel biodegradable polymer microspheres. Journal of Neurosurgery. 120: 1078-85. PMID 24605841 DOI: 10.3171/2014.1.Jns13235  0.352
2014 Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Science Translational Medicine. 6: 224ra24. PMID 24553385 DOI: 10.1126/Scitranslmed.3007094  0.334
2014 Yohay K, Tyler B, Weaver KD, Pardo AC, Gincel D, Blakeley J, Brem H, Rothstein JD. Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models. Journal of Neurosurgery. 120: 854-63. PMID 24484234 DOI: 10.3171/2013.12.Jns13641  0.378
2014 Bydon M, Ma TM, Xu R, Weingart J, Olivi A, Gokaslan ZL, Tamargo RJ, Brem H, Bydon A. Surgical outcomes of craniocervial junction meningiomas: a series of 22 consecutive patients. Clinical Neurology and Neurosurgery. 117: 71-9. PMID 24438809 DOI: 10.1016/J.Clineuro.2013.11.023  0.547
2014 Bow H, Hwang LS, Schildhaus N, Xing J, Murray L, Salditch Q, Ye X, Zhang Y, Weingart J, Brem H, Tyler B. Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma. Journal of Neurosurgery. 120: 662-9. PMID 24359008 DOI: 10.3171/2013.11.Jns13556  0.391
2014 Chaichana KL, Jusue-Torres I, Navarro-Ramirez R, Raza SM, Pascual-Gallego M, Ibrahim A, Hernandez-Hermann M, Gomez L, Ye X, Weingart JD, Olivi A, Blakeley J, Gallia GL, Lim M, Brem H, et al. Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma. Neuro-Oncology. 16: 113-22. PMID 24285550 DOI: 10.1093/Neuonc/Not137  0.355
2014 Grossman R, Brastianos H, Blakeley JO, Mangraviti A, Lal B, Zadnik P, Hwang L, Wicks RT, Goodwin RC, Brem H, Tyler B. Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models. Journal of Neuro-Oncology. 116: 59-65. PMID 24185441 DOI: 10.1007/S11060-013-1268-2  0.375
2014 Chaichana KL, Acharya S, Flores M, Wijesekera O, Rigamonti D, Weingart JD, Olivi A, Bettegowda C, Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Identifying better surgical candidates among recursive partitioning analysis class 2 patients who underwent surgery for intracranial metastases. World Neurosurgery. 82: e267-75. PMID 24076052 DOI: 10.1016/J.Wneu.2013.08.031  0.356
2014 Chaichana KL, Rao K, Gadkaree S, Dangelmajer S, Bettegowda C, Rigamonti D, Weingart J, Olivi A, Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Factors associated with survival and recurrence for patients undergoing surgery of cerebellar metastases. Neurological Research. 36: 13-25. PMID 24070068 DOI: 10.1179/1743132813Y.0000000260  0.362
2014 Mangraviti A, Tzeng S, Seng M, Abbadi S, Kozielski K, Schiapparelli P, Wijesekera O, Sarabia-Estrada R, Brem H, Tyler B, Olivi A, Green J, Quinones-Hinojosa A. SC-17 * BMP4-SECRETING hAdMSCs ENGINEERED WITH NANOPARTICLES: A NON-VIRAL MSC-BASED THERAPY FOR GLIOBLASTOMA Neuro-Oncology. 16: v200-v201. DOI: 10.1093/Neuonc/Nou275.17  0.315
2014 Mathios D, Phallen J, Park C, Jackson C, Nicholas S, Tyler B, Pardoll D, Brem H, Lim M. It-21Pd-1 Blockade Shows Synergistic Survival, Anti-Tumor Immune Response And Long-Term Memory With Interstitial But Not Systemic Chemotherapy: Study In A Murine Glioblastoma Model. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou258.19  0.308
2014 Mangraviti A, Sengupta S, Paldor I, Rowshanshad D, Sampath P, Olivi A, Tyler B, Brem H. IT-20OVEREXPRESSION OF IL13Ra2: ASSESSMENT OF PRO-AGGRESSIVE AND PRO-INVASIVE PHENOTYPES OF MALIGNANT GLIOMA IN A SYNGENEIC ANIMAL MODEL Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou258.18  0.33
2014 Mangraviti A, Jin Y, Sy J, Wang Y, Raghavan T, Hastings-Spaine L, Olivi A, Tyler B, Brem H. ET-37 * EFFICACY OF INTRACRANIAL DELIVERY OF DICHLOROACETATE AND CARBOPLATIN VIA AN LCP POLYMER MICROCAPSULE DEVICE IN AN EXPERIMENTAL GLIOMA MODEL Neuro-Oncology. 16: v87-v87. DOI: 10.1093/Neuonc/Nou255.37  0.379
2013 Baia GS, Caballero OL, Ho JS, Zhao Q, Cohen T, Binder ZA, Salmasi V, Gallia GL, Quinones-Hinojosa A, Olivi A, Brem H, Burger P, Strausberg RL, Simpson AJ, Eberhart CG, et al. NY-ESO-1 expression in meningioma suggests a rationale for new immunotherapeutic approaches. Cancer Immunology Research. 1: 296-302. PMID 24777967 DOI: 10.1158/2326-6066.Cir-13-0029  0.333
2013 Chaichana KL, Flores M, Acharya S, Sampognaro P, Bettegowda C, Rigamonti D, Weingart JD, Olivi A, Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Survival and recurrence for patients undergoing surgery of skull base intracranial metastases. Journal of Neurological Surgery. Part B, Skull Base. 74: 228-35. PMID 24436917 DOI: 10.1055/S-0033-1342925  0.372
2013 Chaichana KL, Gadkaree S, Rao K, Link T, Rigamonti D, Purtell M, Browner I, Weingart J, Olivi A, Gallia G, Bettegowda C, Brem H, Lim M, Quinones-Hinojosa A. Patients undergoing surgery of intracranial metastases have different outcomes based on their primary pathology. Neurological Research. 35: 1059-69. PMID 24070329 DOI: 10.1179/1743132813Y.0000000253  0.389
2013 Nabors LB, Ammirati M, Bierman PJ, Brem H, Butowski N, Chamberlain MC, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hesser D, Holdhoff M, Junck L, Lawson R, Loeffler JS, et al. Central nervous system cancers. Journal of the National Comprehensive Cancer Network : Jnccn. 11: 1114-51. PMID 24029126 DOI: 10.6004/Jnccn.2013.0132  0.401
2013 Sattler R, Tyler B, Hoover B, Coddington LT, Recinos V, Hwang L, Brem H, Rothstein JD. Increased expression of glutamate transporter GLT-1 in peritumoral tissue associated with prolonged survival and decreases in tumor growth in a rat model of experimental malignant glioma. Journal of Neurosurgery. 119: 878-86. PMID 23909244 DOI: 10.3171/2013.6.Jns122319  0.304
2013 Chaichana KL, Martinez-Gutierrez JC, De la Garza-Ramos R, Weingart JD, Olivi A, Gallia GL, Lim M, Brem H, Quinones-Hinojosa A. Factors associated with survival for patients with glioblastoma with poor pre-operative functional status. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 20: 818-23. PMID 23639620 DOI: 10.1016/J.Jocn.2012.07.016  0.358
2013 Zeng J, See AP, Phallen J, Jackson CM, Belcaid Z, Ruzevick J, Durham N, Meyer C, Harris TJ, Albesiano E, Pradilla G, Ford E, Wong J, Hammers HJ, Mathios D, ... ... Brem H, et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. International Journal of Radiation Oncology, Biology, Physics. 86: 343-9. PMID 23462419 DOI: 10.1016/J.Ijrobp.2012.12.025  0.334
2013 Chaichana KL, Pendleton C, Jackson C, Martinez-Gutierrez JC, Diaz-Stransky A, Aguayo J, Olivi A, Weingart J, Gallia G, Lim M, Brem H, Quinones-Hinojosa A. Deep venous thrombosis and pulmonary embolisms in adult patients undergoing craniotomy for brain tumors. Neurological Research. 35: 206-11. PMID 23336127 DOI: 10.1179/1743132812Y.0000000126  0.342
2013 Vellimana AK, Recinos VR, Hwang L, Fowers KD, Li KW, Zhang Y, Okonma S, Eberhart CG, Brem H, Tyler BM. Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model. Journal of Neuro-Oncology. 111: 229-36. PMID 23224713 DOI: 10.1007/S11060-012-1014-1  0.35
2013 Chaichana KL, Zadnik P, Weingart JD, Olivi A, Gallia GL, Blakeley J, Lim M, Brem H, Quiñones-Hinojosa A. Multiple resections for patients with glioblastoma: prolonging survival. Journal of Neurosurgery. 118: 812-20. PMID 23082884 DOI: 10.3171/2012.9.Jns1277  0.383
2012 Chaichana KL, Jackson C, Patel A, Miller NR, Subramanian P, Lim M, Gallia G, Olivi A, Weingart J, Brem H, Quiñones-Hinojosa A. Predictors of visual outcome following surgical resection of medial sphenoid wing meningiomas. Journal of Neurological Surgery. Part B, Skull Base. 73: 321-6. PMID 24083123 DOI: 10.1055/S-0032-1321510  0.321
2012 Rege A, Seifert AC, Schlattman D, Ouyang Y, Li KW, Basaldella L, Brem H, Tyler BM, Thakor NV. Longitudinal in vivo monitoring of rodent glioma models through thinned skull using laser speckle contrast imaging. Journal of Biomedical Optics. 17: 126017. PMID 23235836 DOI: 10.1117/1.Jbo.17.12.126017  0.352
2012 Momin EN, Adams H, Shinohara RT, Frangakis C, Brem H, Quiñones-Hinojosa A. Postoperative mortality after surgery for brain tumors by patient insurance status in the United States. Archives of Surgery (Chicago, Ill. : 1960). 147: 1017-24. PMID 23165616 DOI: 10.1001/Archsurg.2012.1459  0.33
2012 Grossman R, Tyler B, Brem H, Eberhart CG, Wang S, Fu DX, Wen Z, Zhou J. Growth properties of SF188/V+ human glioma in rats in vivo observed by magnetic resonance imaging. Journal of Neuro-Oncology. 110: 315-23. PMID 23011120 DOI: 10.1007/S11060-012-0974-5  0.311
2012 Grossman R, Rudek MA, Brastianos H, Zadnik P, Brem H, Tyler B, Blakeley JO. The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas. Cancer Chemotherapy and Pharmacology. 70: 129-39. PMID 22644796 DOI: 10.1007/S00280-012-1867-1  0.323
2012 Tyler BM, Hdeib A, Caplan J, Legnani FG, Fowers KD, Brem H, Jallo G, Pradilla G. Delayed onset of paresis in rats with experimental intramedullary spinal cord gliosarcoma following intratumoral administration of the paclitaxel delivery system OncoGel. Journal of Neurosurgery. Spine. 16: 93-101. PMID 22208429 DOI: 10.3171/2011.9.Spine11435  0.315
2011 Grossman R, Tyler B, Hwang L, Zadnik P, Lal B, Javaherian K, Brem H. Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin. Journal of Neurosurgery. 115: 1139-46. PMID 21923243 DOI: 10.3171/2011.8.Jns11125  0.403
2011 Chaichana KL, Zaidi H, Pendleton C, McGirt MJ, Grossman R, Weingart JD, Olivi A, Quiñones-Hinojosa A, Brem H. The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival. Neurological Research. 33: 759-64. PMID 21756557 DOI: 10.1179/1743132811Y.0000000006  0.326
2011 Tyler B, Wadsworth S, Recinos V, Mehta V, Vellimana A, Li K, Rosenblatt J, Do H, Gallia GL, Siu IM, Wicks RT, Rudek MA, Zhao M, Brem H. Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats. Neuro-Oncology. 13: 700-9. PMID 21727209 DOI: 10.1093/Neuonc/Nor050  0.397
2011 Grossman R, Mukherjee D, Chang DC, Bennett R, Brem H, Olivi A, Quiñones-Hinojosa A. Preoperative charlson comorbidity score predicts postoperative outcomes among older intracranial meningioma patients. World Neurosurgery. 75: 279-85. PMID 21492731 DOI: 10.1016/J.Wneu.2010.09.003  0.306
2011 Brem SS, Bierman PJ, Brem H, Butowski N, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Friedman A, Gilbert MR, Hesser D, Junck L, Linette GP, Loeffler JS, Maor MH, et al. Central nervous system cancers. Journal of the National Comprehensive Cancer Network : Jnccn. 9: 352-400. PMID 21464144 DOI: 10.6004/Jnccn.2011.0036  0.401
2011 Chaichana KL, Chaichana KK, Olivi A, Weingart JD, Bennett R, Brem H, Quiñones-Hinojosa A. Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article. Journal of Neurosurgery. 114: 587-94. PMID 20887095 DOI: 10.3171/2010.8.Jns1081  0.325
2011 Grossman R, Mukherjee D, Chang DC, Purtell M, Lim M, Brem H, Quiñones-Hinojosa A. Predictors of inpatient death and complications among postoperative elderly patients with metastatic brain tumors. Annals of Surgical Oncology. 18: 521-8. PMID 20809176 DOI: 10.1245/S10434-010-1299-2  0.343
2011 Chaichana KL, Halthore AN, Parker SL, Olivi A, Weingart JD, Brem H, Quinones-Hinojosa A. Factors involved in maintaining prolonged functional independence following supratentorial glioblastoma resection. Clinical article. Journal of Neurosurgery. 114: 604-12. PMID 20524825 DOI: 10.3171/2010.4.Jns091340  0.319
2010 McGirt MJ, Brem H. Carmustine wafers (Gliadel) plus concomitant temozolomide therapy after resection of malignant astrocytoma: growing evidence for safety and efficacy. Annals of Surgical Oncology. 17: 1729-31. PMID 20422453 DOI: 10.1245/S10434-010-1092-2  0.358
2010 Chaichana KL, Kosztowski T, Niranjan A, Olivi A, Weingart JD, Laterra J, Brem H, Quiñones-Hinojosa A. Prognostic significance of contrast-enhancing anaplastic astrocytomas in adults. Journal of Neurosurgery. 113: 286-92. PMID 20302391 DOI: 10.3171/2010.2.Jns091010  0.331
2010 Recinos VR, Tyler BM, Bekelis K, Sunshine SB, Vellimana A, Li KW, Brem H. Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model. Neurosurgery. 66: 530-7; discussion 53. PMID 20173548 DOI: 10.1227/01.Neu.0000365263.14725.39  0.363
2010 Tyler B, Fowers KD, Li KW, Recinos VR, Caplan JM, Hdeib A, Grossman R, Basaldella L, Bekelis K, Pradilla G, Legnani F, Brem H. A thermal gel depot for local delivery of paclitaxel to treat experimental brain tumors in rats. Journal of Neurosurgery. 113: 210-7. PMID 20001591 DOI: 10.3171/2009.11.Jns08162  0.364
2010 Chaichana KL, McGirt MJ, Woodworth GF, Datoo G, Tamargo RJ, Weingart J, Olivi A, Brem H, Quinones-Hinojosa A. Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas. Neurological Research. 32: 442-8. PMID 19589201 DOI: 10.1179/174313209X431101  0.379
2010 Doucette TA, Kong L, Yang Y, Wei J, Wang J, Fuller GN, Heimberger AB, Rao G, Ajewung N, Kamnasaran D, Katz AM, Amankulor N, Squatrito M, Hambardzumyan D, Holland EC, ... ... Brem H, et al. Tumor Models (In Vivo/In Vitro) Neuro-Oncology. 12: iv130-iv136. DOI: 10.1093/Neuonc/Noq116.S20  0.334
2009 Slager J, Tyler B, Shikanov A, Domb AJ, Shogen K, Sidransky D, Brem H. Local controlled delivery of anti-neoplastic RNAse to the brain. Pharmaceutical Research. 26: 1838-46. PMID 19415468 DOI: 10.1007/S11095-009-9893-3  0.36
2009 McGirt MJ, Than KD, Weingart JD, Chaichana KL, Attenello FJ, Olivi A, Laterra J, Kleinberg LR, Grossman SA, Brem H, Quiñones-Hinojosa A. Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme. Journal of Neurosurgery. 110: 583-8. PMID 19046047 DOI: 10.3171/2008.5.17557  0.366
2009 McGirt MJ, Chaichana KL, Gathinji M, Attenello FJ, Than K, Olivi A, Weingart JD, Brem H, Quiñones-Hinojosa AR. Independent association of extent of resection with survival in patients with malignant brain astrocytoma. Journal of Neurosurgery. 110: 156-62. PMID 18847342 DOI: 10.3171/2008.4.17536  0.365
2008 McGirt MJ, Chaichana KL, Attenello FJ, Weingart JD, Than K, Burger PC, Olivi A, Brem H, Quinoñes-Hinojosa A. Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. Neurosurgery. 63: 700-7; author reply . PMID 18981880 DOI: 10.1227/01.Neu.0000325729.41085.73  0.342
2008 Attenello FJ, Mukherjee D, Datoo G, McGirt MJ, Bohan E, Weingart JD, Olivi A, Quinones-Hinojosa A, Brem H. Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience. Annals of Surgical Oncology. 15: 2887-93. PMID 18636295 DOI: 10.1245/S10434-008-0048-2  0.356
2008 Sonabend AM, Velicu S, Ulasov IV, Han Y, Tyler B, Brem H, Matar MM, Fewell JG, Anwer K, Lesniak MS. A safety and efficacy study of local delivery of interleukin-12 transgene by PPC polymer in a model of experimental glioma. Anti-Cancer Drugs. 19: 133-42. PMID 18176109 DOI: 10.1097/Cad.0B013E3282F24017  0.369
2007 Marupudi NI, Han JE, Li KW, Renard VM, Tyler BM, Brem H. Paclitaxel: a review of adverse toxicities and novel delivery strategies. Expert Opinion On Drug Safety. 6: 609-21. PMID 17877447 DOI: 10.1517/14740338.6.5.609  0.37
2007 Kominsky SL, Tyler B, Sosnowski J, Brady K, Doucet M, Nell D, Smedley JG, McClane B, Brem H, Sukumar S. Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis. Cancer Research. 67: 7977-82. PMID 17804705 DOI: 10.1158/0008-5472.Can-07-1314  0.37
2007 Chaichana KL, Capilla-Gonzalez V, Gonzalez-Perez O, Pradilla G, Han J, Olivi A, Brem H, Garcia-Verdugo JM, Quiñones-Hinojosa A. Preservation of glial cytoarchitecture from ex vivo human tumor and non-tumor cerebral cortical explants: A human model to study neurological diseases. Journal of Neuroscience Methods. 164: 261-70. PMID 17580092 DOI: 10.1016/J.Jneumeth.2007.05.008  0.364
2007 Brem S, Tyler B, Li K, Pradilla G, Legnani F, Caplan J, Brem H. Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model. Cancer Chemotherapy and Pharmacology. 60: 643-50. PMID 17256133 DOI: 10.1007/S00280-006-0407-2  0.318
2007 Lawson HC, Sampath P, Bohan E, Park MC, Hussain N, Olivi A, Weingart J, Kleinberg L, Brem H. Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience. Journal of Neuro-Oncology. 83: 61-70. PMID 17171441 DOI: 10.1007/S11060-006-9303-1  0.411
2006 Fruehauf JP, Brem H, Brem S, Sloan A, Barger G, Huang W, Parker R. In vitro drug response and molecular markers associated with drug resistance in malignant gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4523-32. PMID 16899598 DOI: 10.1158/1078-0432.Ccr-05-1830  0.305
2006 Caplan J, Pradilla G, Hdeib A, Tyler BM, Legnani FG, Bagley CA, Brem H, Jallo G. A novel model of intramedullary spinal cord tumors in rats: functional progression and histopathological characterization. Neurosurgery. 59: 193-200; discussion . PMID 16823316 DOI: 10.1227/01.Neu.0000219276.44563.Da  0.311
2006 Sampath P, Rhines LD, DiMeco F, Tyler BM, Park MC, Brem H. Interstitial docetaxel (taxotere), carmustine and combined interstitial therapy: a novel treatment for experimental malignant glioma. Journal of Neuro-Oncology. 80: 9-17. PMID 16636748 DOI: 10.1007/S11060-006-9159-4  0.415
2006 Legnani FG, Pradilla G, Thai QA, Fiorindi A, Recinos PF, Tyler BM, Gaini SM, DiMeco F, Brem H, Olivi A. Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers. Journal of Neuro-Oncology. 77: 225-32. PMID 16609837 DOI: 10.1007/S11060-005-6937-3  0.365
2006 Pradilla G, Wang PP, Gabikian P, Li K, Magee CA, Walter KA, Brem H. Local intracerebral administration of Paclitaxel with the paclimer delivery system: toxicity study in a canine model. Journal of Neuro-Oncology. 76: 131-8. PMID 16284923 DOI: 10.1007/S11060-005-5531-Z  0.305
2005 Mavinkurve G, Pradilla G, Legnani FG, Tyler BM, Bagley CA, Brem H, Jallo G. A novel intramedullary spinal cord tumor model: functional, radiological, and histopathological characterization. Journal of Neurosurgery. Spine. 3: 142-8. PMID 16370303 DOI: 10.3171/Spi.2005.3.2.0142  0.323
2005 Lesniak MS, Upadhyay U, Goodwin R, Tyler B, Brem H. Local delivery of doxorubicin for the treatment of malignant brain tumors in rats. Anticancer Research. 25: 3825-31. PMID 16312042  0.312
2005 Pradilla G, Legnani FG, Petrangolini G, Francescato P, Chillemi F, Tyler BM, Gaini SM, Brem H, Olivi A, DiMeco F. Local delivery of a synthetic endostatin fragment for the treatment of experimental gliomas. Neurosurgery. 57: 1032-40; discussion . PMID 16284573 DOI: 10.1227/01.Neu.0000180059.33665.C1  0.405
2005 Gallia GL, Brem S, Brem H. Local treatment of malignant brain tumors using implantable chemotherapeutic polymers. Journal of the National Comprehensive Cancer Network : Jnccn. 3: 721-8. PMID 16194460 DOI: 10.6004/Jnccn.2005.0042  0.423
2005 Hsu W, Lesniak MS, Tyler B, Brem H. Local delivery of interleukin-2 and adriamycin is synergistic in the treatment of experimental malignant glioma. Journal of Neuro-Oncology. 74: 135-40. PMID 16193383 DOI: 10.1007/S11060-004-6597-8  0.364
2005 Raza SM, Pradilla G, Legnani FG, Thai QA, Olivi A, Weingart JD, Brem H. Local delivery of antineoplastic agents by controlled-release polymers for the treatment of malignant brain tumours. Expert Opinion On Biological Therapy. 5: 477-494. PMID 15934827 DOI: 10.1517/14712598.5.4.477  0.354
2005 Mantha A, Legnani FG, Bagley CA, Gallia GL, Garonzik I, Pradilla G, Amundson E, Tyler BM, Brem H, Gokaslan ZL. A novel rat model for the study of intraosseous metastatic spine cancer. Journal of Neurosurgery. Spine. 2: 303-7. PMID 15796355 DOI: 10.3171/Spi.2005.2.3.0303  0.311
2005 Koenig MA, Geocadin RG, Kulesza P, Olivi A, Brem H. Rhabdoid meningioma occurring in an unrelated resection cavity with leptomeningeal carcinomatosis: Case report Journal of Neurosurgery. 102: 371-375. PMID 15739568 DOI: 10.3171/Jns.2005.102.2.0371  0.337
2005 Chang SM, Parney IF, Huang W, Anderson FA, Asher AL, Bernstein M, Lillehei KO, Brem H, Berger MS, Laws ER. Patterns of care for adults with newly diagnosed malignant glioma. Jama. 293: 557-64. PMID 15687310 DOI: 10.1001/Jama.293.5.557  0.321
2004 Storm PB, Renard VM, Moriarity JL, Tyler B, Wilentz RE, Brem H, Weingart JD. Systemic BCNU enhances the efficacy of local delivery of a topoisomerase I inhibitor against malignant glioma. Cancer Chemotherapy and Pharmacology. 54: 361-7. PMID 15197484 DOI: 10.1007/S00280-004-0800-7  0.312
2004 Lesniak MS, Brem H. Targeted therapy for brain tumours Nature Reviews Drug Discovery. 3: 499-508. PMID 15173839 DOI: 10.1038/Nrd1414  0.345
2004 Samdani AF, Kuchner EB, Rhines L, Adamson DC, Lawson C, Tyler B, Brem H, Dawson VL, Dawson TM. Astroglia induce cytotoxic effects on brain tumors via a nitric oxide-dependent pathway both in vitro and in vivo. Neurosurgery. 54: 1231-7; discussion 1. PMID 15113479 DOI: 10.1227/01.Neu.0000119576.76193.B8  0.386
2004 Kleinberg LR, Weingart J, Burger P, Carson K, Grossman SA, Li K, Olivi A, Wharam MD, Brem H. Clinical Course and Pathologic Findings after Gliadel® and Radiotherapy for Newly Diagnosed Malignant Glioma: Implications for Patient Management Cancer Investigation. 22: 1-9. PMID 15069758 DOI: 10.1081/Cnv-120027575  0.385
2004 Håberg A, Kvistad KA, Unsgård G, Haraldseth O, Weiss N, Brem H, Takakura K, Sawaya R, Langmoen IA. Preoperative Blood Oxygen Level-dependent Functional Magnetic Resonance Imaging in Patients with Primary Brain Tumors: Clinical Application and Outcome Neurosurgery. 54: 902-915. PMID 15046657 DOI: 10.1227/01.Neu.0000114510.05922.F8  0.343
2004 Guerin C, Olivi A, Weingart JD, Lawson HC, Brem H. Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Investigational New Drugs. 22: 27-37. PMID 14707492 DOI: 10.1023/B:Drug.0000006172.65135.3E  0.429
2004 Komotar RJ, Burger PC, Carson BS, Brem H, Olivi A, Goldthwaite PT, Tihan T. Pilocytic and pilomyxoid hypothalamic/chiasmatic astrocytomas. Neurosurgery. 54: 72-9; discussion 79-. PMID 14683543 DOI: 10.1227/01.Neu.0000097266.89676.25  0.332
2003 Legnani FG, Pradilla G, Wang PP, Brem H, Olivi A, DiMeco F. Local delivery of antineoplastic agents using biodegradable polymers for the treatment of malignant brain tumors Expert Review of Neurotherapeutics. 3: 533-546. PMID 19810937 DOI: 10.1586/14737175.3.4.533  0.438
2003 Moses MA, Brem H, Langer R. Advancing the field of drug delivery: Taking aim at cancer Cancer Cell. 4: 337-341. PMID 14667500 DOI: 10.1016/S1535-6108(03)00276-9  0.302
2003 Frazier JL, Wang PP, Case D, Tyler BM, Pradilla G, Weingart JD, Brem H. Local delivery of minocycline and systemic BCNU have synergistic activity in the treatment of intracranial glioma. Journal of Neuro-Oncology. 64: 203-9. PMID 14558595 DOI: 10.1023/A:1025695423097  0.417
2003 Laws ER, Parney IF, Huang W, Anderson F, Morris AM, Asher A, Lillehei KO, Bernstein M, Brem H, Sloan A, Berger MS, Chang S. Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. Journal of Neurosurgery. 99: 467-73. PMID 12959431 DOI: 10.3171/Jns.2003.99.3.0467  0.348
2003 Lesniak MS, Tyler BM, Pardoll DM, Brem H. Gene therapy for experimental brain tumors using a xenogenic cell line engineered to secrete hIL-2. Journal of Neuro-Oncology. 64: 155-60. PMID 12952296 DOI: 10.1007/BF02700030  0.397
2003 Chang SM, Parney IF, McDermott M, Barker FG, Schmidt MH, Huang W, Laws ER, Lillehei KO, Bernstein M, Brem H, Sloan AE, Berger M. Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. Journal of Neurosurgery. 98: 1175-81. PMID 12816260 DOI: 10.3171/Jns.2003.98.6.1175  0.344
2003 Rhines LD, Sampath P, DiMeco F, Lawson HC, Tyler BM, Hanes J, Olivi A, Brem H. Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma. Neurosurgery. 52: 872-9; discussion 87. PMID 12657184 DOI: 10.1227/01.Neu.0000053211.39087.D1  0.36
2003 Sampath P, Amundson E, Wall ME, Tyler BM, Wani MC, Alderson LM, Colvin M, Brem H, Weingart JD. Camptothecin analogs in malignant gliomas: comparative analysis and characterization. Journal of Neurosurgery. 98: 570-7. PMID 12650430 DOI: 10.3171/Jns.2003.98.3.0570  0.377
2003 Long DM, Gordon T, Bowman H, Etzel A, Burleyson G, Betchen S, Garonzik IM, Brem H. Outcome and cost of craniotomy performed to treat tumors in regional academic referral centers. Neurosurgery. 52: 1056-1065. DOI: 10.1227/01.Neu.0000057745.48813.93  0.301
2002 Lugassy C, Haroun RI, Brem H, Tyler BM, Jones RV, Fernandez PM, Patierno SR, Kleinman HK, Barnhill RL. Pericytic-like angiotropism of glioma and melanoma cells. The American Journal of Dermatopathology. 24: 473-8. PMID 12454598 DOI: 10.1097/00000372-200212000-00003  0.343
2002 DiMeco F, Li KW, Tyler BM, Wolf AS, Brem H, Olivi A. Local delivery of mitoxantrone for the treatment of malignant brain tumors in rats. Journal of Neurosurgery. 97: 1173-8. PMID 12450040 DOI: 10.3171/Jns.2002.97.5.1173  0.403
2002 Wang PP, Frazier J, Brem H. Local drug delivery to the brain Advanced Drug Delivery Reviews. 54: 987-1013. PMID 12384318 DOI: 10.1016/S0169-409X(02)00054-6  0.407
2002 Toung TJ, Tyler B, Brem H, Traystman RJ, Hurn PD, Bhardwaj A. Hypertonic saline ameliorates cerebral edema associated with experimental brain tumor. Journal of Neurosurgical Anesthesiology. 14: 187-93. PMID 12172290 DOI: 10.1097/00008506-200207000-00003  0.38
2002 Haroun RI, Clatterbuck RE, Gibbons MC, Burger PC, Parker R, Fruehauf JP, Brem H. Extreme drug resistance in primary brain tumors: in vitro analysis of 64 resection specimens. Journal of Neuro-Oncology. 58: 115-23. PMID 12164682 DOI: 10.1023/A:1016049111941  0.354
2002 Storm PB, Moriarity JL, Tyler B, Burger PC, Brem H, Weingart J. Polymer delivery of camptothecin against 9L gliosarcoma: release, distribution, and efficacy. Journal of Neuro-Oncology. 56: 209-17. PMID 12061726 DOI: 10.1023/A:1015003232713  0.366
2002 Liu JM, Garonzik IM, Eberhart CG, Sampath P, Brem H. Ectopic recurrence of craniopharyngioma after an interhemispheric transcallosal approach: case report. Neurosurgery. 50: 639-44; discussion 6. PMID 11841735 DOI: 10.1097/00006123-200203000-00041  0.349
2001 Lesniak MS, Langer R, Brem H. Drug delivery to tumors of the central nervous system Current Neurology and Neuroscience Reports. 1: 210-216. PMID 11898520 DOI: 10.1007/S11910-001-0020-Z  0.395
2001 Reavey-Cantwell JF, Haroun RI, Zahurak M, Clatterbuck RE, Parker RJ, Mehta R, Fruehauf JP, Brem H. The prognostic value of tumor markers in patients with glioblastoma multiforme: analysis of 32 patients and review of the literature. Journal of Neuro-Oncology. 55: 195-204. PMID 11859975 DOI: 10.1023/A:1013845004294  0.379
2001 Rothstein JD, Brem H. Excitotoxic destruction facilitates brain tumor growth. Nature Medicine. 7: 994-5. PMID 11533696 DOI: 10.1038/Nm0901-994  0.323
2001 Hanes J, Sills A, Zhao Z, Suh KW, Tyler B, DiMeco F, Brat DJ, Choti MA, Leong KW, Pardoll DM, Brem H. Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors. Pharmaceutical Research. 18: 899-906. PMID 11496947 DOI: 10.1023/A:1010963307097  0.382
2001 Brem H, Gabikian P. Biodegradable polymer implants to treat brain tumors. Journal of Controlled Release. 74: 63-67. PMID 11489483 DOI: 10.1016/S0168-3659(01)00311-X  0.429
2001 Sipos EP, Witham TF, Ratan R, Burger PC, Baraban J, Li KW, Piantadosi S, Brem H. L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model. Neurosurgery. 48: 392-400. PMID 11220384 DOI: 10.1097/00006123-200102000-00032  0.415
2000 Lesniak MS, Sampath P, DiMeco F, Viglione MP, Tyler BM, Pardoll DM, Brem H. Comparative analysis of paracrine immunotherapy in experimental brain tumors. Neurosurgical Focus. 9: e4. PMID 16817687 DOI: 10.3171/Foc.2000.9.6.5  0.336
2000 Sipos EP, Brem H. Local Anti-angiogenic Brain Tumor Therapies Journal of Neuro-Oncology. 50: 181-188. PMID 11245278 DOI: 10.1023/A:1006482120049  0.43
2000 Ewend MG, Thompson RC, Anderson R, Sills AK, Staveley-O'Carroll K, Tyler BM, Hanes J, Brat D, Thomas M, Jaffee EM, Pardoll DM, Brem H. Intracranial paracrine interleukin-2 therapy stimulates prolonged antitumor immunity that extends outside the central nervous system. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 438-48. PMID 10916753 DOI: 10.1097/00002371-200007000-00007  0.385
2000 Haroun RI, Brem H. Local drug delivery. Current Opinion in Oncology. 12: 187-193. PMID 10841189 DOI: 10.1097/00001622-200005000-00001  0.319
2000 Haroun RI, Li KW, Carson BS, Brem H. Primary Tumors of the Choroid Plexus Contemporary Neurosurgery. 22: 1-8. DOI: 10.1097/00029679-200002010-00001  0.337
2000 Weingart J, Brem H, Grossman S, Burger P, Wharam M, Kleinberg L. Gliadel followed by radiotherapy for newly diagnosed malignant glioma: Safety results, pathologic findings, and survival International Journal of Radiation Oncology*Biology*Physics. 48: 256. DOI: 10.1016/S0360-3016(00)80310-7  0.325
1999 Suh KW, Piantadosi S, Yazdi HA, Pardoll DM, Brem H, Choti MA. Treatment of liver metastases from colon carcinoma with autologous tumor vaccine expressing granulocyte-macrophage colony-stimulating factor Journal of Surgical Oncology. 72: 218-224. PMID 10589037 DOI: 10.1002/(Sici)1096-9098(199912)72:4<218::Aid-Jso7>3.0.Co;2-N  0.345
1999 Brem H, Lawson HC. The development of new brain tumor therapy utilizing the local and sustained delivery of chemotherapeutic agents from biodegradable polymers Cancer. 86: 197-199. PMID 10421254 DOI: 10.1002/(Sici)1097-0142(19990715)86:2<197::Aid-Cncr2>3.0.Co;2-6  0.386
1998 Sampath P, Brem H. Implantable Slow-Release Chemotherapeutic Polymers for the Treatment of Malignant Brain Tumors. Cancer Control. 5: 130-137. PMID 10761024 DOI: 10.1177/107327489800500204  0.454
1998 Grossman SA, Fisher JD, Piantadosi S, Brem H. The New Approaches to Brain Tumor Therapy (NABTT) CNS Consortium: Organization, Objectives, and Activities. Cancer Control. 5: 107-114. PMID 10761021 DOI: 10.1177/107327489800500201  0.405
1998 Williams JA, Yuan X, Dillehay LE, Shastri VR, Brem H, Williams JR. Synthetic, implantable polymers for local delivery of IUdR to experimental human malignant glioma. International Journal of Radiation Oncology Biology Physics. 42: 631-639. PMID 9806525 DOI: 10.1016/S0360-3016(98)00258-2  0.372
1998 Ewend MG, Sampath P, Williams JA, Tyler BM, Brem H. Local delivery of chemotherapy prolongs survival in experimental brain metastases from breast carcinoma. Neurosurgery. 43: 1185-93. PMID 9802862 DOI: 10.1097/00006123-199811000-00093  0.369
1997 Kleinberg LR, Slick T, Enger C, Grossman S, Brem H, Wharam MD. Short course radiotherapy is an appropriate option for most malignant glioma patients International Journal of Radiation Oncology Biology Physics. 38: 31-36. PMID 9212001 DOI: 10.1016/S0360-3016(97)00222-8  0.354
1997 Sipos EP, Tyler B, Piantadosi S, Burger PC, Brem H. Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors. Cancer Chemotherapy and Pharmacology. 39: 383-9. PMID 9054951 DOI: 10.1007/S002800050588  0.36
1997 Williams JA, Dillehay LE, Tabassi K, Sipos E, Fahlman C, Brem H. Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma Journal of Neuro-Oncology. 32: 181-192. PMID 9049879 DOI: 10.1023/A:1005704913330  0.349
1996 Thompson RC, Pardoll DM, Jaffee EM, Ewend MG, Thomas MC, Tyler BM, Brem H. Systemic and local paracrine cytokine therapies using transduced tumor cells are synergistic in treating intracranial tumors. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 19: 405-13. PMID 9041459 DOI: 10.1097/00002371-199611000-00004  0.356
1996 Olivi A, Ewend MG, Utsuki T, Tyler B, Domb AJ, Brat DJ, Brem H. Interstitial delivery of carboplatin via biodegradable polymers is effective against experimental glioma in the rat. Cancer Chemotherapy and Pharmacology. 39: 90-6. PMID 8995504 DOI: 10.1007/S002800050542  0.381
1996 Ewend MG, Carey LA, Brem H. Treatment of melanoma metastases in the brain Seminars in Surgical Oncology. 12: 429-435. PMID 8914207 DOI: 10.1002/(Sici)1098-2388(199611/12)12:6<429::Aid-Ssu8>3.0.Co;2-C  0.351
1996 Fung LK, Shin M, Tyler B, Brem H, Saltzman WM. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Pharmaceutical Research. 13: 671-82. PMID 8860421 DOI: 10.1023/A:1016083113123  0.317
1996 Utsuki T, Brem H, Pitha J, Loftsson T, Kristmundsdottir T, Tyler BM, Olivi A. Potentiation of anticancer effects of microencapsulated carboplatin by hydroxypropyl α-cyclodextrin Journal of Controlled Release. 40: 251-260. DOI: 10.1016/0168-3659(95)00192-1  0.334
1995 Brem H, Ewend MG, Piantadosi S, Greenhoot J, Burger PC, Sisti M. The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial. Journal of Neuro-Oncology. 26: 111-23. PMID 8787853 DOI: 10.1007/Bf01060217  0.36
1995 Buahin KG, Brem H. Interstitial chemotherapy of experimental brain tumors: comparison of intratumoral injection versus polymeric controlled release. Journal of Neuro-Oncology. 26: 103-110. PMID 8787852 DOI: 10.1007/Bf01060216  0.369
1995 Weingart JD, Sipos EP, Brem H. The role of minocycline in the treatment of intracranial 9L glioma. Journal of Neurosurgery. 82: 635-640. PMID 7897527 DOI: 10.3171/Jns.1995.82.4.0635  0.399
1995 Judy KD, Olivi A, Buahin KG, Domb A, Epstein JI, Colvin OM, Brem H. Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas Journal of Neurosurgery. 82: 481-486. PMID 7861228 DOI: 10.3171/Jns.1995.82.3.0481  0.363
1995 Brem H, Piantadosi S, Burger PC, Walker M, Selker R, Vick NA, Black K, Sisti M, Brem S, Mohr G. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group. Lancet. 345: 1008-12. PMID 7723496 DOI: 10.1016/S0140-6736(95)90755-6  0.391
1995 Weingart JD, Thompson RC, Tyler B, Colvin OM, Brem H. Local delivery of the topoisomerase I inhibitor camptothecin sodium prolongs survival in the rat intracranial 9L gliosarcoma model. International Journal of Cancer. Journal International Du Cancer. 62: 605-9. PMID 7665233 DOI: 10.1002/Ijc.2910620519  0.416
1995 Sipos EP, Brem H. New delivery systems for brain tumor therapy Neurologic Clinics. 13: 813-825. DOI: 10.1016/S0733-8619(18)30019-7  0.395
1994 Brem H, Tamargo RJ, Olivi A, Pinn M, Weingart JD, Wharam M, Epstein JI. Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain Journal of Neurosurgery. 80: 283-290. PMID 8283268 DOI: 10.3171/Jns.1994.80.2.0283  0.353
1994 Olivi A, Brem H. Interstitial Chemotherapy with Sustained-Release Polymer Systems for the Treatment of Malignant Gliomas Recent Results in Cancer Research. 135: 149-154. PMID 8047689 DOI: 10.1007/978-3-642-85039-4_15  0.417
1994 Arosarena O, Guerin C, Brem H, Laterra J. Endothelial differentiation in intracerebral and subcutaneous experimental gliomas. Brain Research. 640: 98-104. PMID 8004469 DOI: 10.1016/0006-8993(94)91861-9  0.359
1994 Cahan MA, Walter KA, Colvin OM, Brem H. Cytotoxicity of taxol in vitro against human and rat malignant brain tumors Cancer Chemotherapy and Pharmacology. 33: 441-444. PMID 7905792 DOI: 10.1007/Bf00686276  0.357
1994 Tapper D, Cahan MA, Brem H. Detection of biological activity in the cerebrospinal fluid of patients with central nervous system tumors. Journal of Neuro-Oncology. 19: 17-23. PMID 7815101 DOI: 10.1007/Bf01051045  0.375
1994 Sipos EP, Tamargo RJ, Weingart JD, Brem H. Inhibition of tumor angiogenesis. Annals of the New York Academy of Sciences. 732: 263-272. PMID 7526758 DOI: 10.1111/J.1749-6632.1994.Tb24741.X  0.357
1994 Tamargo RJ, Langer R, Brem H. Interstitial Drug Delivery to the Central Nervous System Using Controlled Release Polymers: Chemotherapy for Brain Tumors Methods in Neurosciences. 21: 135-149. DOI: 10.1016/B978-0-12-185291-7.50014-X  0.358
1993 Wolff JE, Guerin C, Laterra J, Bressler J, Indurti RR, Brem H, Goldstein GW. Dexamethasone reduces vascular density and plasminogen activator activity in 9L rat brain tumors. Brain Research. 604: 79-85. PMID 7681348 DOI: 10.1016/0006-8993(93)90354-P  0.363
1993 Olivi A, Kim KD, Benedetti L, Epstein JI, Pinn ML, Callegaro L, Brem H. Ocular and brain biocompatibility of polymeric delivery materials prepared from ester derivatives of hyaluronic acid Clinical Materials. 13: 163-168. DOI: 10.1016/0267-6605(93)90104-F  0.323
1992 Phillips SD, Corio RL, Brem H, Mattox D. Ameloblastoma of the Mandible With Intracranial Metastasis: A Case Study Archives of Otolaryngology--Head and Neck Surgery. 118: 861-863. PMID 1642839 DOI: 10.1001/Archotol.1992.01880080083018  0.324
1992 Guerin C, Wolff JE, Laterra J, Drewes LR, Brem H, Goldstein GW. Vascular differentiation and glucose transporter expression in rat gliomas: effects of steroids. Annals of Neurology. 31: 481-7. PMID 1596083 DOI: 10.1002/Ana.410310504  0.309
1992 Griffin CA, Long PP, Carson BS, Brem H. Chromosome abnormalities in low-grade central nervous system tumors Cancer Genetics and Cytogenetics. 60: 67-73. PMID 1591709 DOI: 10.1016/0165-4608(92)90235-Z  0.342
1992 Brem H, Domb A, Lenartz D, Dureza C, Olivi A, Epstein JI. Brain biocompatibility of a biodegradable controlled release polymer consisting of anhydride copolymer of fatty acid dimer and sebacic acid Journal of Controlled Release. 19: 325-329. DOI: 10.1016/0168-3659(92)90087-8  0.327
1992 Buahin KG, Judy KD, Hartke C, Domb AJ, Maniar M, Colvin OM, Brem H. Controlled release of 4-hydroperoxycyclophosphamide from the fatty acid dimer-sebacic acid copolymer Polymers For Advanced Technologies. 3: 311-316. DOI: 10.1002/Pat.1992.220030605  0.336
1991 Tamargo RJ, Sills AK, Reinhard CS, Pinn ML, Long DM, Brem H. Interstitial delivery of dexamethasone in the brain for the reduction of peritumoral edema Journal of Neurosurgery. 74: 956-961. PMID 2033457 DOI: 10.3171/Jns.1991.74.6.0956  0.347
1991 Olivi A, Donehower RC, Mann RB, Brem H. Solitary, isolated metastasis from Ewing's sarcoma to the brain: case report. Surgical Neurology. 35: 239-243. PMID 1996454 DOI: 10.1016/0090-3019(91)90078-N  0.352
1991 Brem H, Mahaley MS, Vick NA, Black KL, Schold SC, Burger PC, Friedman AH, Ciric IS, Eller TW, Cozzens JW. Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. Journal of Neurosurgery. 74: 441-6. PMID 1993909 DOI: 10.3171/Jns.1991.74.3.0441  0.406
1991 Madrid Y, Langer LF, Brem H, Langer R. New directions in the delivery of drugs and other substances to the central nervous system. Advances in Pharmacology (San Diego, Calif.). 22: 299-324. PMID 1958504 DOI: 10.1016/S1054-3589(08)60039-3  0.307
1991 Reinhard CS, Radomsky ML, Saltzman W, Hilton J, Brem H. Polymeric controlled release of dexamethasone in normal rat brain Journal of Controlled Release. 16: 331-339. DOI: 10.1016/0168-3659(91)90010-B  0.312
1990 Brem H. Polymers to treat brain tumours Biomaterials. 11: 699-701. PMID 2090306 DOI: 10.1016/0142-9612(90)90030-T  0.342
1990 Tamargo RJ, Leong KW, Brem H. Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate. Journal of Neuro-Oncology. 9: 131-138. PMID 1702149 DOI: 10.1007/Bf02427833  0.391
1990 Chasin M, Hollenbeck G, Brem H, Grossman SA, Colvin M, Langer R. Interstitial Drug Therapy for Brain Tumors: A Case Study Drug Development and Industrial Pharmacy. 16: 2579-2594. DOI: 10.3109/03639049009058548  0.405
1989 Steen RG, Tamargo RJ, Brem H, Glickson JD, Wehrle JP. In vivo 31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: Dose response of spectral changes Magnetic Resonance in Medicine. 11: 258-266. PMID 2779416 DOI: 10.1002/Mrm.1910110214  0.3
1988 Robey SS, Olson JL, Brem H, Epstein JI. Posterior fossa neuroblastoma occurring in an elderly man Human Pathology. 19: 365-367. PMID 3346012 DOI: 10.1016/S0046-8177(88)80533-1  0.341
1988 Tamargo RJ, Epstein JI, Brem H. Heterotransplantation of malignant human gliomas in neonatal rats Journal of Neurosurgery. 69: 928-933. PMID 3193198 DOI: 10.3171/Jns.1988.69.6.0928  0.302
1975 Brem H, Folkman J. Inhibition of tumor angiogenesis mediated by cartilage. Journal of Experimental Medicine. 141: 427-439. PMID 1113064 DOI: 10.1084/Jem.141.2.427  0.334
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