☰

Leslie Alexander - Publications

Affiliations: 
2008-2012 Chemistry University of California, San Diego and San Diego State University 
Tree Info Similar researchers PubMed Report error

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 McConnell JR, Alexander LA, McAlpine SR. A heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing the heat shock response. Bioorganic & Medicinal Chemistry Letters. 24: 661-6. PMID 24360559 DOI: 10.1016/J.Bmcl.2013.11.059  0.746
2012 Ramsey DM, McConnell JR, Alexander LD, Tanaka KW, Vera CM, McAlpine SR. An Hsp90 modulator that exhibits a unique mechanistic profile. Bioorganic & Medicinal Chemistry Letters. 22: 3287-90. PMID 22480433 DOI: 10.1016/J.Bmcl.2012.03.012  0.82
2012 Davis MR, Singh EK, Wahyudi H, Alexander LD, Kunicki JB, Nazarova LA, Fairweather KA, Giltrap AM, Jolliffe KA, McAlpine SR. Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds. Tetrahedron. 68: 1029-1051. PMID 22287031 DOI: 10.1016/J.Tet.2011.11.089  0.749
2011 Alexander LD, Partridge JR, Agard DA, McAlpine SR. A small molecule that preferentially binds the closed conformation of Hsp90. Bioorganic & Medicinal Chemistry Letters. 21: 7068-71. PMID 22014826 DOI: 10.1016/J.Bmcl.2011.09.096  0.703
2011 Ardi VC, Alexander LD, Johnson VA, McAlpine SR. Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteins. Acs Chemical Biology. 6: 1357-66. PMID 21950602 DOI: 10.1021/Cb200203M  0.789
2011 Kunicki JB, Petersen MN, Alexander LD, Ardi VC, McConnell JR, McAlpine SR. Synthesis and evaluation of biotinylated sansalvamide A analogs and their modulation of Hsp90. Bioorganic & Medicinal Chemistry Letters. 21: 4716-9. PMID 21764310 DOI: 10.1016/J.Bmcl.2011.06.083  0.796
2010 Singh EK, Nazarova LA, Lapera SA, Alexander LD, McAlpine SR. Histone Deacetylase Inhibitors: Synthesis of Cyclic Tetrapeptides and their Triazole Analogues. Tetrahedron Letters. 51: 4357-4360. PMID 20865132 DOI: 10.1016/J.Tetlet.2010.06.050  0.748
2010 Sellers RP, Alexander LD, Johnson VA, Lin CC, Savage J, Corral R, Moss J, Slugocki TS, Singh EK, Davis MR, Ravula S, Spicer JE, Oelrich JL, Thornquist A, Pan CM, et al. Design and synthesis of Hsp90 inhibitors: exploring the SAR of Sansalvamide A derivatives. Bioorganic & Medicinal Chemistry. 18: 6822-56. PMID 20708938 DOI: 10.1016/J.Bmc.2010.07.042  0.638
2010 Johnson VA, Singh EK, Nazarova LA, Alexander LD, McAlpine SR. Macrocyclic inhibitors of hsp90. Current Topics in Medicinal Chemistry. 10: 1380-402. PMID 20536417 DOI: 10.2174/156802610792232088  0.762
2009 Alexander LD, Sellers RP, Davis MR, Ardi VC, Johnson VA, Vasko RC, McAlpine SR. Evaluation of di-sansalvamide A derivatives: synthesis, structure-activity relationship, and mechanism of action. Journal of Medicinal Chemistry. 52: 7927-30. PMID 20014866 DOI: 10.1021/Jm901566C  0.748
2008 Singh EK, Sellers RP, Alexander LD, McAlpine SR. Conformationally based design of macrocycles as antitumor agents. Current Opinion in Drug Discovery & Development. 11: 544-52. PMID 18600570  0.763
Show low-probability matches.