Richard Goodwin - Publications

Affiliations: 
1996 Computer Science Carnegie Mellon University, Pittsburgh, PA 

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Brüning-Richardson A, Shaw GC, Tams D, Brend T, Sanganee H, Barry ST, Hamm G, Goodwin RJA, Swales JG, King H, Steele L, Morton R, Widyadari A, Ward TA, Esteves F, et al. GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models. Cancers. 13. PMID 34885051 DOI: 10.3390/cancers13235939  1
2021 Harmon KA, Roman S, Lancaster HD, Chowhury S, Cull E, Goodwin RL, Arce S, Fanning S. Structural and Ultrastructural Analysis of the Multiple Myeloma Cell Niche and a Patient-Specific Model of Plasma Cell Dysfunction. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 1-11. PMID 34881690 DOI: 10.1017/S1431927621013805  1
2021 Strittmatter N, Kanvatirth P, Inglese P, Race AM, Nilsson A, Dannhorn A, Kudo H, Goldin RD, Ling S, Wong E, Seeliger F, Serra MP, Hoffmann S, Maglennon G, Hamm G, ... ... Goodwin RJA, et al. Holistic Characterization of a Typhimurium Infection Model Using Integrated Molecular Imaging. Journal of the American Society For Mass Spectrometry. PMID 34767352 DOI: 10.1021/jasms.1c00240  1
2021 Skinner WH, Chung M, Mitchell S, Akidil A, Fabre K, Goodwin R, Stokes AA, Radacsi N, Campbell CJ. A SERS-Active Electrospun Polymer Mesh for Spatially Localized pH Measurements of the Cellular Microenvironment. Analytical Chemistry. PMID 34609126 DOI: 10.1021/acs.analchem.1c02530  1
2021 de Jesus JM, Costa C, Burton A, Palitsin V, Webb R, Taylor A, Nikula C, Dexter A, Kaya F, Chambers M, Dartois V, Goodwin RJA, Bunch J, Bailey MJ. Correlative Imaging of Trace Elements and Intact Molecular Species in a Single-Tissue Sample at the 50 μm Scale. Analytical Chemistry. PMID 34597513 DOI: 10.1021/acs.analchem.1c01927  1
2021 Flint LE, Hamm G, Ready JD, Ling S, Duckett CJ, Cross NA, Cole LM, Smith DP, Goodwin RJA, Clench MR. Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging. Metabolites. 11. PMID 34436447 DOI: 10.3390/metabo11080506  1
2021 Goodwin RL, Kheradvar A, Norris RA, Price RL, Potts JD. Collagen Fibrillogenesis in the Mitral Valve: It's a Matter of Compliance. Journal of Cardiovascular Development and Disease. 8. PMID 34436240 DOI: 10.3390/jcdd8080098  1
2021 Shariatgorji R, Nilsson A, Fridjonsdottir E, Strittmatter N, Dannhorn A, Svenningsson P, Goodwin RJA, Odell LR, Andrén PE. Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging. Nature Protocols. PMID 34075230 DOI: 10.1038/s41596-021-00538-w  1
2021 I Nathaniel T, Goodwin RL, Fowler L, Mcphail B, Black AC. An adaptive blended learning model for the implementation of an integrated medical neuroscience course during the Covid-19 pandemic. Anatomical Sciences Education. PMID 33915035 DOI: 10.1002/ase.2097  0.01
2021 Constantinou S, Evans J, Goodwin RG. Fifteen-minute consultation: How to manage eczema in children. Archives of Disease in Childhood. Education and Practice Edition. PMID 33658292 DOI: 10.1136/archdischild-2020-320560  0.01
2021 Strittmatter N, England RM, Race AM, Sutton D, Moss JI, Maglennon G, Ling S, Wong E, Rose J, Purvis I, Macdonald R, Barry ST, Ashford MB, Goodwin RJA. Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry. Analytical Chemistry. PMID 33606520 DOI: 10.1021/acs.analchem.0c03908  1
2021 Race AM, Sutton D, Hamm G, Maglennon G, Morton JP, Strittmatter N, Campbell A, Sansom OJ, Wang Y, Barry ST, Takáts Z, Goodwin RJA, Bunch J. Deep Learning-Based Annotation Transfer between Molecular Imaging Modalities: An Automated Workflow for Multimodal Data Integration. Analytical Chemistry. PMID 33534548 DOI: 10.1021/acs.analchem.0c02726  1
2021 Dannhorn A, Ling S, Powell S, McCall E, Maglennon G, Jones GN, Pierce AJ, Strittmatter N, Hamm G, Barry ST, Bunch J, Goodwin RJA, Takats Z. Evaluation of UV-C Decontamination of Clinical Tissue Sections for Spatially Resolved Analysis by Mass Spectrometry Imaging (MSI). Analytical Chemistry. PMID 33474935 DOI: 10.1021/acs.analchem.0c03430  1
2021 Fala M, Somai V, Dannhorn A, Hamm G, Gibson K, Couturier DL, Hesketh R, Wright AJ, Takats Z, Bunch J, Barry ST, Goodwin RJA, Brindle KM. Comparison of C MRI of hyperpolarized [1- C]pyruvate and lactate with the corresponding mass spectrometry images in a murine lymphoma model. Magnetic Resonance in Medicine. PMID 33421253 DOI: 10.1002/mrm.28652  1
2021 Najumudeen AK, Ceteci F, Fey SK, Hamm G, Steven RT, Hall H, Nikula CJ, Dexter A, Murta T, Race AM, Sumpton D, Vlahov N, Gay DM, Knight JRP, Jackstadt R, ... ... Goodwin RJA, et al. The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer. Nature Genetics. 53: 16-26. PMID 33414552 DOI: 10.1038/s41588-020-00753-3  1
2021 Murta T, Steven RT, Nikula CJ, Thomas SA, Zeiger LB, Dexter A, Elia EA, Yan B, Campbell AD, Goodwin RJA, Takáts Z, Sansom OJ, Bunch J. Implications of Peak Selection in the Interpretation of Unsupervised Mass Spectrometry Imaging Data Analyses. Analytical Chemistry. PMID 33395266 DOI: 10.1021/acs.analchem.0c04179  1
2020 Colclough N, Chen K, Johnström P, Strittmatter N, Yan Y, Wrigley GL, Schou M, Goodwin RJA, Varnäs K, Adua SJ, Zhao M, Nguyen DX, Maglennon GA, Barton P, Atkinson J, et al. Preclinical comparison of the blood brain barrier (BBB) permeability of osimertinib with other EGFR TKIs. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33028591 DOI: 10.1158/1078-0432.CCR-19-1871  1
2020 Pararajasingam A, Goodwin R. In-transit metastases: the migration of melanoma. British Journal of Hospital Medicine (London, England : 2005). 81: 1. PMID 32990085 DOI: 10.12968/hmed.2020.0202  0.01
2020 Flint LE, Hamm GR, Ready JD, Ling S, Duckett CJ, Cross NA, Cole LM, Smith DP, Goodwin RJA, Clench MR. The Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging. Analytical Chemistry. PMID 32786495 DOI: 10.1021/acs.analchem.0c02389  1
2020 Schuijs MJ, Png S, Richard AC, Tsyben A, Hamm G, Stockis J, Garcia C, Pinaud S, Nicholls A, Ros XR, Su J, Eldridge MD, Riedel A, Serrao EM, Rodewald HR, ... ... Goodwin RJA, et al. ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung. Nature Immunology. PMID 32747815 DOI: 10.1038/s41590-020-0745-y  1
2020 Goodwin RJA, Takats Z, Bunch J. A Critical and Concise Review of Mass Spectrometry Applied to Imaging in Drug Discovery. Slas Discovery : Advancing Life Sciences R & D. 2472555220941843. PMID 32713279 DOI: 10.1177/2472555220941843  1
2020 Shariatgorji R, Nilsson A, Strittmatter N, Vallianatou T, Zhang X, Svenningsson P, Goodwin RJA, Andren PE. Bromopyrylium derivatization facilitates identification by mass spectrometry imaging of monoamine neurotransmitters and small molecule neuroactive compounds. Journal of the American Society For Mass Spectrometry. PMID 32633532 DOI: 10.1021/jasms.0c00166  1
2020 Dannhorn A, Kazanc E, Ling S, Nikula C, Karali E, Serra MP, Vorng JL, Inglese P, Maglennon G, Hamm GR, Swales JG, Strittmatter N, Barry S, Samson OJ, Poulogiannis G, ... ... Goodwin RJA, et al. Universal sample preparation unlocking multimodal molecular tissue imaging. Analytical Chemistry. PMID 32519547 DOI: 10.1021/acs.analchem.0c00826  1
2020 Hulme H, Meikle LM, Strittmatter N, van der Hooft JJJ, Swales J, Bragg RA, Villar VH, Ormsby MJ, Barnes S, Brown SL, Dexter A, Kamat MT, Komen JC, Walker D, Milling S, ... ... Goodwin RJA, et al. Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication. Science Advances. 6: eaax6328. PMID 32195337 DOI: 10.1126/Sciadv.Aax6328  1
2020 Moss JI, Barjat H, Emmas SA, Strittmatter N, Maynard J, Goodwin RJA, Storm G, Lammers T, Puri S, Ashford MB, Barry ST. High-resolution 3D visualization of nanomedicine distribution in tumors. Theranostics. 10: 880-897. PMID 31903157 DOI: 10.7150/thno.37178  1
2020 Goodwin R. Case series of dementia with Lewy bodies: consensus criteria in practice. Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists. 28: 80-83. PMID 31884808 DOI: 10.1177/1039856219891649  0.01
2019 Lewis HM, Webb R, Verbeck GF, Bunch J, de Jesus J, Costa C, Palitsin V, Swales JG, Goodwin RJA, Sears P, Bailey MJ. Nanoextraction coupled to liquid chromatography mass spectrometry delivers improved spatially resolved analysis. Analytical Chemistry. PMID 31747247 DOI: 10.1021/Acs.Analchem.9B02821  1
2019 Havlikova J, Randall EC, Griffiths RL, Swales JG, Goodwin RJA, Bunch J, Styles IB, Cooper HJ. Quantitative Imaging of Proteins in Tissue by Stable Isotope Labelled Mimetic Liquid Extraction Surface Analysis (SLiM LESA) Mass Spectrometry. Analytical Chemistry. PMID 31660728 DOI: 10.1021/acs.analchem.9b04148  1
2019 Mullins SR, Vasilakos JP, Deschler K, Grigsby I, Gillis P, John J, Elder MJ, Swales J, Timosenko E, Cooper Z, Dovedi SJ, Leishman AJ, Luheshi N, Elvecrog J, Tilahun A, ... Goodwin R, et al. Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies. Journal For Immunotherapy of Cancer. 7: 244. PMID 31511088 DOI: 10.1186/S40425-019-0724-8  0.01
2019 Hamm GR, Bäckström E, Brülls M, Nilsson A, Strittmatter N, Andrén PE, Grime K, Fridén M, Goodwin RJA. Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging. Journal of Aerosol Medicine and Pulmonary Drug Delivery. PMID 31364961 DOI: 10.1089/jamp.2019.1536  1
2019 Tucker LH, Hamm GR, Sargeant RJE, Goodwin RJA, Mackay CL, Campbell CJ, Clarke DJ. Untargeted Metabolite Mapping in 3D Cell Culture Models using High Spectral Resolution FT-ICR Mass Spectrometry Imaging. Analytical Chemistry. PMID 31265253 DOI: 10.1021/Acs.Analchem.9B00661  1
2019 Davison AS, Strittmatter N, Sutherland H, Hughes AT, Hughes J, Bou-Gharios G, Milan AM, Goodwin RJA, Ranganath LR, Gallagher JA. Correction to: Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging. Metabolomics : Official Journal of the Metabolomic Society. 15: 81. PMID 31104147 DOI: 10.1007/S11306-019-1540-3  1
2019 Davison AS, Strittmatter N, Sutherland H, Hughes AT, Hughes J, Bou-Gharios G, Milan AM, Goodwin RJA, Ranganath LR, Gallagher JA. Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging. Metabolomics : Official Journal of the Metabolomic Society. 15: 68. PMID 31037385 DOI: 10.1007/s11306-019-1531-4  1
2019 Rao JU, Gibson K, Hamm G, Wright A, Fala M, Mair R, Tsyben A, Goodwin R, Brindle K. Cbmt-33. Visualizing The Metabolism Of Glioblastoma Patient-Derived Orthotopic Xenografts By Mass Spectrometry Imaging Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.155  1
2018 Dand N, Duckworth M, Baudry D, Russell A, Curtis CJ, Lee SH, Evans I, Mason KJ, Alsharqi A, Becher G, Burden AD, Goodwin RG, McKenna K, Murphy R, Perera GK, et al. HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis. The Journal of Allergy and Clinical Immunology. PMID 30578879 DOI: 10.1016/j.jaci.2018.11.038  0.01
2018 Griffiths RL, Simmonds AL, Swales JG, Goodwin RJA, Cooper HJ. LESA MS imaging of heat preserved and frozen tissue: Benefits of multi-step static FAIMS. Analytical Chemistry. PMID 30350618 DOI: 10.1021/acs.analchem.8b02739  1
2018 de Jesus J, Bunch J, Verbeck G, Webb RP, Costa C, Goodwin RJA, Bailey MJ. Application of Various Normalization Methods for Microscale Analysis of Tissues Using Direct Analyte Probed Nanoextraction. Analytical Chemistry. PMID 30260213 DOI: 10.1021/Acs.Analchem.8B03016  1
2018 Lopez-Clavijo AF, Griffiths RL, Goodwin RJA, Cooper HJ. Liquid Extraction Surface Analysis (LESA) Electron-Induced Dissociation and Collision-Induced Dissociation Mass Spectrometry of Small Molecule Drug Compounds. Journal of the American Society For Mass Spectrometry. PMID 30151679 DOI: 10.1007/s13361-018-2042-7  1
2018 Tucker L, Conde-González A, Cobice D, Hamm G, Goodwin RJA, Campbell CJ, Clarke DJ, Mackay CL. MALDI Matrix Application Utilizing a Modified 3D Printer for Accessible High Resolution Mass Spectrometry Imaging. Analytical Chemistry. PMID 29863333 DOI: 10.1021/Acs.Analchem.8B00670  1
2018 Harmon KA, Lane BA, Boone RE, Afshari A, Berdel HO, Yost MJ, Goodwin RL, Friedman HI, Eberth JF. Therapeutic Engineered Hydrogel Coatings Attenuate the Foreign Body Response in Submuscular Implants. Annals of Plastic Surgery. PMID 29746273 DOI: 10.1097/Sap.0000000000001347  1
2018 Swales JG, Dexter A, Hamm G, Nilsson A, Strittmatter N, Michopoulos F, Hardy C, Morentin-Gutierrez P, Mellor M, Andren PE, Clench MR, Bunch J, Critchlow SE, Goodwin RJA. Quantitation of endogenous metabolites in mouse tumors using mass spectrometry imaging. Analytical Chemistry. PMID 29668267 DOI: 10.1021/acs.analchem.7b05239  1
2018 Bäckström E, Hamm G, Nilsson A, Fihn BM, Strittmatter N, Andrén P, Goodwin RJA, Fridén M. Uncovering the regional localization of inhaled salmeterol retention in the lung. Drug Delivery. 25: 838-845. PMID 29587546 DOI: 10.1080/10717544.2018.1455762  1
2018 Griffiths F, Armoiry X, Atherton H, Bryce C, Buckle A, Cave JAK, Court RA, Hamilton K, Dliwayo TR, Dritsaki M, Elder P, Forjaz V, Fraser J, Goodwin R, Huxley CJ, et al. The role of digital communication in patient-clinician communication for NHS providers of specialist clinical services for young people (The LYNC study): a mixed methods study Health Services and Delivery Research. 6: 1-270. PMID 29485818 DOI: 10.3310/Hsdr06090  0.01
2018 Charkoftaki G, Rattray NJW, Andrén PE, Caprioli RM, Castellino S, Duncan MW, Goodwin RJA, Schey KL, Shahidi-Latham SK, Veselkov KA, Johnson CH, Vasiliou V. Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. Human Genomics. 12: 10. PMID 29482659 DOI: 10.1186/S40246-018-0142-X  1
2018 Lane BA, Harmon KA, Goodwin RL, Yost MJ, Shazly T, Eberth JF. Constitutive modeling of compressible type-I collagen hydrogels. Medical Engineering & Physics. PMID 29396019 DOI: 10.1016/J.Medengphy.2018.01.003  1
2018 Vallianatou T, Strittmatter N, Nilsson A, Shariatgorji M, Hamm G, Pereira M, Källback P, Svenningsson P, Karlgren M, Goodwin RJA, Andrén PE. A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability. Neuroimage. PMID 29329980 DOI: 10.1016/J.Neuroimage.2018.01.013  1
2018 Rao JU, Gibson K, Hamm G, Wright A, Fala M, Mair R, Goodwin R, Brindle K. Cbmt-13. Unravelling Metabolism Of Glioblastoma Using Mass Spectrometry Imaging Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.132  1
2017 Kheradvar A, Zareian R, Kawauchi S, Goodwin RL, Rugonyi S. Animal Models for Heart Valve Research and Development. Drug Discovery Today. Disease Models. 24: 55-62. PMID 30631375 DOI: 10.1016/J.Ddmod.2018.04.001  0.01
2017 Dexter A, Race AM, Steven RT, Barnes JR, Hulme H, Goodwin RJA, Styles IB, Bunch J. Two-phase and graph based clustering methods for accurate and efficient segmentation of large mass spectrometry images. Analytical Chemistry. PMID 28849641 DOI: 10.1021/acs.analchem.7b01758  1
2017 Nilsson A, Peric A, Strimfors M, Goodwin RJA, Hayes MA, Andrén PE, Hilgendorf C. Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis. Scientific Reports. 7: 6352. PMID 28743866 DOI: 10.1038/s41598-017-06583-4  1
2017 Jones RS, Chang PH, Perahia T, Harmon KA, Junor L, Yost MJ, Fan D, Eberth JF, Goodwin RL. Design and Fabrication of a Three-Dimensional In Vitro System for Modeling Vascular Stenosis. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 1-13. PMID 28712382 DOI: 10.1017/S1431927617012302  1
2017 Hulme HE, Meikle LM, Wessel H, Strittmatter N, Swales J, Thomson C, Nilsson A, Nibbs RJB, Milling S, Andren PE, Mackay CL, Dexter A, Bunch J, Goodwin RJA, Burchmore R, et al. Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection. Scientific Reports. 7: 2786. PMID 28584281 DOI: 10.1038/s41598-017-03100-5  1
2017 Goodwin RJ, Bunch J, McGinnity DF. Mass Spectrometry Imaging in Oncology Drug Discovery. Advances in Cancer Research. 134: 133-171. PMID 28110649 DOI: 10.1016/bs.acr.2016.11.005  1
2016 Swales JG, Strittmatter N, Tucker JW, Clench MR, Webborn PJ, Goodwin RJ. Spatial Quantitation of Drugs in tissues using Liquid Extraction Surface Analysis Mass Spectrometry Imaging. Scientific Reports. 6: 37648. PMID 27883030 DOI: 10.1038/srep37648  1
2016 Cobice DF, Livingstone DE, Mackay CL, Goodwin RJ, Smith LB, Walker BR, Andrew R. Spatial Localization and Quantitation of Androgens in Mouse Testis by Mass Spectrometry Imaging. Analytical Chemistry. PMID 27676129 DOI: 10.1021/acs.analchem.6b02242  1
2016 Goodwin R, Chander T, Shah N, Tomlin S. INHALER COUNSELLING, THE REAL DEAL OR JUST FRESH AIR? Archives of Disease in Childhood. 101: e2. PMID 27540215 DOI: 10.1136/archdischild-2016-311535.35  0.01
2016 Shariatgorji M, Strittmatter N, Nilsson A, Källback P, Alvarsson A, Zhang X, Vallianatou T, Svenningsson P, Goodwin RJ, Andren PE. Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry. Neuroimage. PMID 27155126 DOI: 10.1016/J.Neuroimage.2016.05.004  1
2016 Curtis MP, Vaillancourt V, Goodwin RM, Chubb NA, Howson W, McTier TL, Pullins A, Zinser EW, Meeus PF, Woods DJ, Hedges L, Stuk T, Price JE, Koch JD, Menon SR. Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs. Bioorganic & Medicinal Chemistry Letters. 26: 1831-5. PMID 26920802 DOI: 10.1016/j.bmcl.2016.02.027  1
2016 Ashton S, Song YH, Nolan J, Cadogan E, Murray J, Odedra R, Foster J, Hall PA, Low S, Taylor P, Ellston R, Polanska UM, Wilson J, Howes C, Smith A, ... Goodwin RJ, et al. Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo. Science Translational Medicine. 8: 325ra17. PMID 26865565 DOI: 10.1126/Scitranslmed.Aad2355  1
2016 Andren PE, Nilsson A, Shariatgorji M, Goodwin R. Investigating drug-induced toxicity in tissue samples using mass spectrometry imaging Toxicology Letters. 258. DOI: 10.1016/J.Toxlet.2016.06.1252  1
2015 Menon V, Eberth JF, Goodwin RL, Potts JD. Altered Hemodynamics in the Embryonic Heart Affects Outflow Valve Development. Journal of Cardiovascular Development and Disease. 2: 108-124. PMID 26878022 DOI: 10.3390/Jcdd2020108  1
2015 Goodwin RJ, Nilsson A, Mackay CL, Swales JG, Johansson MK, Billger M, Andrén PE, Iverson SL. Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections. Journal of Biomolecular Screening. PMID 26701101 DOI: 10.1177/1087057115623740  1
2015 Goodwin RJ, Webborn PJ. Future directions of imaging MS in pharmaceutical R&D. Bioanalysis. 7: 2667-73. PMID 26510897 DOI: 10.4155/bio.15.156  1
2015 Goodwin R, Heraghty J. Do healthcare professionals understand asthma devices? Archives of Disease in Childhood. Education and Practice Edition. 100: 302-5. PMID 26407731 DOI: 10.1136/archdischild-2015-308779  0.01
2015 Swales JG, Tucker JW, Spreadborough MJ, Iverson SL, Clench MR, Webborn PJ, Goodwin RJ. Mapping Drug Distribution in Brain Tissue Using Liquid Extraction Surface Analysis Mass Spectrometry Imaging. Analytical Chemistry. PMID 26350423 DOI: 10.1021/acs.analchem.5b02998  1
2015 Nilsson A, Goodwin RJ, Swales JG, Gallagher R, Shankaran H, Sathe A, Pradeepan S, Xue A, Keirstead N, Sasaki JC, Andren PE, Gupta A. Investigating Nephrotoxicity of Polymyxin Derivatives by Mapping Renal Distribution Using Mass Spectrometry Imaging. Chemical Research in Toxicology. 28: 1823-30. PMID 26293472 DOI: 10.1021/acs.chemrestox.5b00262  1
2015 Cobice DF, Goodwin RJ, Andren PE, Nilsson A, Mackay CL, Andrew R. Future technology insight: mass spectrometry imaging as a tool in drug research and development. British Journal of Pharmacology. 172: 3266-83. PMID 25766375 DOI: 10.1111/bph.13135  1
2015 Nilsson A, Goodwin RJ, Shariatgorji M, Vallianatou T, Webborn PJ, Andrén PE. Mass spectrometry imaging in drug development. Analytical Chemistry. 87: 1437-55. PMID 25526173 DOI: 10.1021/Ac504734S  1
2015 Goodwin R, Swales J, Nilsson A, Andren P, Strittmatter N, Takats Z, Howes C, Taylor P, Ashton S, Jewsbury P, Barry ST. Abstract 3678: Imaging AZD1152HQPA Accurin™ nanoparticle accumulation in preclinical tumors Cancer Research. 75: 3678-3678. DOI: 10.1158/1538-7445.Am2015-3678  1
2014 Shariatgorji M, Nilsson A, Goodwin RJ, Källback P, Schintu N, Zhang X, Crossman AR, Bezard E, Svenningsson P, Andren PE. Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections. Neuron. 84: 697-707. PMID 25453841 DOI: 10.1016/J.Neuron.2014.10.011  1
2014 Curtis MP, Chubb N, Ellsworth E, Goodwin R, Holzmer S, Koch J, McTier T, Menon S, Mills K, Pullins A, Stuk T, Zinser E. The discovery of isoxazoline oxime ethers as a new class of ectoparasiticides for the control of Haematobia irritans (horn fly) in cattle. Bioorganic & Medicinal Chemistry Letters. 24: 5011-4. PMID 25278232 DOI: 10.1016/j.bmcl.2014.09.023  1
2014 Oomman A, Goodwin R. Biological skin substitutes to treat toxic epidermal necrolysis in a case with human immunodeficiency virus infection. Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences. 19: 577-9. PMID 25197304  0.01
2014 Krishnamurthy VK, Evans AN, Wansapura JP, Osinska H, Maddy KE, Biechler SV, Narmoneva DA, Goodwin RL, Hinton RB. Asymmetric cell-matrix and biomechanical abnormalities in elastin insufficiency induced aortopathy. Annals of Biomedical Engineering. 42: 2014-28. PMID 25099772 DOI: 10.1007/S10439-014-1072-Y  1
2014 Swales JG, Tucker JW, Strittmatter N, Nilsson A, Cobice D, Clench MR, Mackay CL, Andren PE, Takáts Z, Webborn PJ, Goodwin RJ. Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis. Analytical Chemistry. 86: 8473-80. PMID 25084360 DOI: 10.1021/ac502217r  1
2014 DiEgidio P, Friedman HI, Gourdie RG, Riley AE, Yost MJ, Goodwin RL. Biomedical implant capsule formation: lessons learned and the road ahead. Annals of Plastic Surgery. 73: 451-60. PMID 25046663 DOI: 10.1097/Sap.0000000000000287  1
2014 Biechler SV, Junor L, Evans AN, Eberth JF, Price RL, Potts JD, Yost MJ, Goodwin RL. The impact of flow-induced forces on the morphogenesis of the outflow tract. Frontiers in Physiology. 5: 225. PMID 24987377 DOI: 10.3389/Fphys.2014.00225  1
2013 Cobice DF, Mackay CL, Goodwin RJ, McBride A, Langridge-Smith PR, Webster SP, Walker BR, Andrew R. Mass spectrometry imaging for dissecting steroid intracrinology within target tissues. Analytical Chemistry. 85: 11576-84. PMID 24134553 DOI: 10.1021/ac402777k  1
2013 Li N, Goodwin RL, Potts JD. Zyxin regulates cell migration and differentiation in EMT during chicken AV valve morphogenesis Microscopy and Microanalysis. 19: 842-854. PMID 23742986 DOI: 10.1017/S1431927613001633  1
2013 Tan H, Biechler S, Junor L, Yost MJ, Dean D, Li J, Potts JD, Goodwin RL. Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves Developmental Biology. 374: 345-356. PMID 23261934 DOI: 10.1016/J.Ydbio.2012.11.023  1
2012 Nilsson A, Forngren B, Bjurström S, Goodwin RJ, Basmaci E, Gustafsson I, Annas A, Hellgren D, Svanhagen A, Andrén PE, Lindberg J. In situ mass spectrometry imaging and ex vivo characterization of renal crystalline deposits induced in multiple preclinical drug toxicology studies. Plos One. 7: e47353. PMID 23110069 DOI: 10.1371/journal.pone.0047353  1
2012 Shariatgorji M, Nilsson A, Goodwin RJ, Svenningsson P, Schintu N, Banka Z, Kladni L, Hasko T, Szabo A, Andren PE. Deuterated matrix-assisted laser desorption ionization matrix uncovers masked mass spectrometry imaging signals of small molecules. Analytical Chemistry. 84: 7152-7. PMID 22860714 DOI: 10.1021/Ac301498M  1
2012 Sauls K, De Vlaming A, Harris BS, Williams K, Wessels A, Levine RA, Slaugenhaupt SA, Goodwin RL, Pavone LM, Merot J, Schott JJ, Le Tourneau T, Dix T, Jesinkey S, Feng Y, et al. Developmental basis for filamin-A-associated myxomatous mitral valve disease Cardiovascular Research. 96: 109-119. PMID 22843703 DOI: 10.1093/Cvr/Cvs238  1
2012 Goodwin RJ, Nilsson A, Borg D, Langridge-Smith PR, Harrison DJ, Mackay CL, Iverson SL, Andrén PE. Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation. Journal of Proteomics. 75: 4912-20. PMID 22796569 DOI: 10.1016/J.Jprot.2012.07.006  1
2012 Yanny S, Cahir JG, Barker T, Wimhurst J, Nolan JF, Goodwin RW, Marshall T, Toms AP. MRI of aseptic lymphocytic vasculitis-associated lesions in metal-on-metal hip replacements. Ajr. American Journal of Roentgenology. 198: 1394-402. PMID 22623554 DOI: 10.2214/AJR.11.7504  1
2012 Goodwin RJ. Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences. Journal of Proteomics. 75: 4893-911. PMID 22554910 DOI: 10.1016/j.jprot.2012.04.012  0.01
2012 Shariatgorji M, Källback P, Gustavsson L, Schintu N, Svenningsson P, Goodwin RJ, Andren PE. Controlled-pH tissue cleanup protocol for signal enhancement of small molecule drugs analyzed by MALDI-MS imaging. Analytical Chemistry. 84: 4603-7. PMID 22507246 DOI: 10.1021/Ac203322Q  1
2012 Goodwin RJ, Iverson SL, Andren PE. The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging. Rapid Communications in Mass Spectrometry : Rcm. 26: 494-8. PMID 22302488 DOI: 10.1002/rcm.6125  1
2011 Goodwin RJ, Mackay CL, Nilsson A, Harrison DJ, Farde L, Andren PE, Iverson SL. Qualitative and quantitative MALDI imaging of the positron emission tomography ligands raclopride (a D2 dopamine antagonist) and SCH 23390 (a D1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method. Analytical Chemistry. 83: 9694-701. PMID 22077717 DOI: 10.1021/ac202630t  1
2011 Wang R, Yun JX, Yuan X, Goodwin R, Markwald RR, Gaoa BZ. Megahertz streak-mode Fourier domain optical coherence tomography Journal of Biomedical Optics. 16. PMID 21721817 DOI: 10.1117/1.3593149  1
2011 Arbuckle W, Baker J, Barn D, Bingham M, Brown A, Buchanan K, Craighead M, Goodwin R, Goutcher S, Kiczun M, Lyons A, Milne R, Montgomery B, Napier S, Presland J, et al. Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 21: 4622-8. PMID 21700453 DOI: 10.1016/j.bmcl.2011.05.092  1
2011 Napier S, Wishart G, Arbuckle W, Baker J, Barn D, Bingham M, Brown A, Byford A, Claxton C, Craighead M, Buchanan K, Fielding L, Gibson L, Goodwin R, Goutcher S, et al. The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 3163-7. PMID 21458261 DOI: 10.1016/j.bmcl.2011.02.096  1
2011 Goodwin RJ, Pitt AR, Harrison D, Weidt SK, Langridge-Smith PR, Barrett MP, Logan Mackay C. Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 25: 969-72. PMID 21416534 DOI: 10.1002/Rcm.4939  1
2011 Valarmathi MT, Fuseler JW, Goodwin RL, Davis JM, Potts JD. The mechanical coupling of adult marrow stromal stem cells during cardiac regeneration assessed in a 2-D co-culture model. Biomaterials. 32: 2834-50. PMID 21288568 DOI: 10.1016/J.Biomaterials.2011.01.012  1
2011 Singh CK, Kumar A, Hitchcock DB, Fan D, Goodwin R, LaVoie HA, Nagarkatti P, DiPette DJ, Singh US. Resveratrol prevents embryonic oxidative stress and apoptosis associated with diabetic embryopathy and improves glucose and lipid profile of diabetic dam. Molecular Nutrition & Food Research. 55: 1186-96. PMID 21254394 DOI: 10.1002/Mnfr.201000457  1
2011 Tan H, Junor L, Price RL, Norris RA, Potts JD, Goodwin RL. Expression and deposition of fibrous extracellular matrix proteins in cardiac valves during chick development Microscopy and Microanalysis. 17: 91-100. PMID 21205426 DOI: 10.1017/S1431927610094365  1
2011 Cappell J, Karim M, Goodwin R. Conference report: Seventh Exploratory Measurement Science Group Symposium. Bioanalysis. 3: 17-9. PMID 21175362 DOI: 10.4155/bio.10.176  1
2011 Brown AR, Bosies M, Cameron H, Clark J, Cowley A, Craighead M, Elmore MA, Firth A, Goodwin R, Goutcher S, Grant E, Grassie M, Grove SJ, Hamilton NM, Hampson H, et al. Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 21: 137-40. PMID 21129964 DOI: 10.1016/j.bmcl.2010.11.054  1
2011 Angus D, Bingham M, Buchanan D, Dunbar N, Gibson L, Goodwin R, Haunsø A, Houghton A, Huggett M, Morphy R, Napier S, Nimz O, Passmore J, Walker G. The identification, and optimisation of hERG selectivity, of a mixed NET/SERT re-uptake inhibitor for the treatment of pain. Bioorganic & Medicinal Chemistry Letters. 21: 271-5. PMID 21112782 DOI: 10.1016/j.bmcl.2010.11.021  1
2011 Cowley PM, Baker J, Barn DR, Buchanan KI, Carlyle I, Clark JK, Clarkson TR, Deehan M, Edwards D, Goodwin RR, Jaap D, Kiyoi Y, Mort C, Palin R, Prosser A, et al. The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 497-501. PMID 21075628 DOI: 10.1016/j.bmcl.2010.10.104  1
2011 Anderson H, Toms AP, Cahir JG, Goodwin RW, Wimhurst J, Nolan JF. Grading the severity of soft tissue changes associated with metal-on-metal hip replacements: reliability of an MR grading system. Skeletal Radiology. 40: 303-7. PMID 20658133 DOI: 10.1007/s00256-010-1000-7  1
2010 Goodwin RJ, Pitt AR. Mass spectrometry imaging of pharmacological compounds in tissue sections. Bioanalysis. 2: 279-93. PMID 21083310 DOI: 10.4155/bio.09.180  1
2010 Goodwin RJ, Macintyre L, Watson DG, Scullion SP, Pitt AR. A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules. Rapid Communications in Mass Spectrometry : Rcm. 24: 1682-6. PMID 20486266 DOI: 10.1002/rcm.4567  1
2010 Reid M, Carlyle I, Caulfield WL, Clarkson TR, Cusick F, Epemolu O, Gilfillan R, Goodwin R, Jaap D, O'Donnell EC, Presland J, Rankovic Z, Spinks D, Spinks G, Thomson AM, et al. The discovery and SAR of indoline-3-carboxamides--a new series of 5-HT6 antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 3713-6. PMID 20471831 DOI: 10.1016/j.bmcl.2010.04.085  1
2010 Logan MS, Propst JT, Nottingham JM, Goodwin RL, Pabon DF, Terracio L, Yost MJ, Fann SA. Human satellite progenitor cells for use in myofascial repair: isolation and characterization. Annals of Plastic Surgery. 64: 794-9. PMID 20407365 DOI: 10.1097/Sap.0B013E3181B025Cb  1
2010 Goodwin RJ, Scullion P, Macintyre L, Watson DG, Pitt AR. Use of a solvent-free dry matrix coating for quantitative matrix-assisted laser desorption ionization imaging of 4-bromophenyl-1,4-diazabicyclo(3.2.2)nonane-4-carboxylate in rat brain and quantitative analysis of the drug from laser microdissected tissue regions. Analytical Chemistry. 82: 3868-73. PMID 20380422 DOI: 10.1021/ac100398y  1
2010 Goodwin RJ, Lang AM, Allingham H, Borén M, Pitt AR. Stopping the clock on proteomic degradation by heat treatment at the point of tissue excision. Proteomics. 10: 1751-61. PMID 20217868 DOI: 10.1002/pmic.200900641  1
2010 Valarmathi MT, Goodwin RL, Fuseler JW, Davis JM, Yost MJ, Potts JD. A 3-D cardiac muscle construct for exploring adult marrow stem cell based myocardial regeneration. Biomaterials. 31: 3185-200. PMID 20129663 DOI: 10.1016/J.Biomaterials.2010.01.041  1
2010 Biechler SV, Potts JD, Yost MJ, Junor L, Goodwin RL, Weidner JW. Mathematical modeling of flow-generated forces in an in vitro system of cardiac valve development. Annals of Biomedical Engineering. 38: 109-17. PMID 19862617 DOI: 10.1007/S10439-009-9824-9  1
2009 Soder BL, Propst JT, Brooks TM, Goodwin RL, Friedman HI, Yost MJ, Gourdie RG. The connexin43 carboxyl-terminal peptide ACT1 modulates the biological response to silicone implants. Plastic and Reconstructive Surgery. 123: 1440-51. PMID 19407614 DOI: 10.1097/Prs.0B013E3181A0741D  1
2009 Norris RA, Potts JD, Yost MJ, Junor L, Brooks T, Tan H, Hoffman S, Hart MM, Kern MJ, Damon B, Markwald RR, Goodwin RL. Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cells Developmental Dynamics. 238: 1052-1063. PMID 19334280 DOI: 10.1002/Dvdy.21933  1
2009 Nesbitt TL, Roberts A, Tan H, Junor L, Yost MJ, Potts JD, Dettman RW, Goodwin RL. Coronary endothelial proliferation and morphogenesis are regulated by a VEGF-mediated pathway Developmental Dynamics. 238: 423-430. PMID 19161222 DOI: 10.1002/Dvdy.21847  1
2009 Valarmathi MT, Davis JM, Yost MJ, Goodwin RL, Potts JD. A three-dimensional model of vasculogenesis Biomaterials. 30: 1098-1112. PMID 19027154 DOI: 10.1016/J.Biomaterials.2008.10.044  1
2008 Goodwin RJ, Pennington SR, Pitt AR. Protein and peptides in pictures: imaging with MALDI mass spectrometry. Proteomics. 8: 3785-800. PMID 18712772 DOI: 10.1002/pmic.200800320  1
2008 Goodwin RJ, Dungworth JC, Cobb SR, Pitt AR. Time-dependent evolution of tissue markers by MALDI-MS imaging. Proteomics. 8: 3801-8. PMID 18712770 DOI: 10.1002/pmic.200800201  1
2008 Valarmathi MT, Yost MJ, Goodwin RL, Potts JD. A three-dimensional tubular scaffold that modulates the osteogenic and vasculogenic differentiation of rat bone marrow stromal cells. Tissue Engineering. Part A. 14: 491-504. PMID 18352828 DOI: 10.1089/Tea.2007.0235  1
2008 Norris RA, Moreno-Rodriguez RA, Sugi Y, Hoffman S, Amos J, Hart MM, Potts JD, Goodwin RL, Markwald RR. Periostin regulates atrioventricular valve maturation Developmental Biology. 316: 200-213. PMID 18313657 DOI: 10.1016/J.Ydbio.2008.01.003  1
2008 Valarmathi MT, Yost MJ, Goodwin RL, Potts JD. The influence of proepicardial cells on the osteogenic potential of marrow stromal cells in a three-dimensional tubular scaffold Biomaterials. 29: 2203-2216. PMID 18289664 DOI: 10.1016/J.Biomaterials.2008.01.025  1
2007 Nesbitt TL, Patel PA, Yost MJ, Goodwin RL, Potts JD. A 3-D model of coronary vessel development In Vitro Cellular and Developmental Biology - Animal. 43: 10-16. PMID 17570028 DOI: 10.1007/S11626-006-9007-Z  1
2007 Evans HJ, Edwards L, Goodwin RL. Conserved C-terminal domains of mCenp-F (LEK1) regulate subcellular localization and mitotic checkpoint delay. Experimental Cell Research. 313: 2427-37. PMID 17498689 DOI: 10.1016/J.Yexcr.2007.03.035  1
2007 Evans HJ, Goodwin RL. Western array analysis of cell cycle protein changes during the hyperplastic to hypertrophic transition in heart development. Molecular and Cellular Biochemistry. 303: 189-99. PMID 17457520 DOI: 10.1007/S11010-007-9473-Y  1
2007 Norris RA, Damon B, Mironov V, Kasyanov V, Ramamurthi A, Moreno-Rodriguez R, Trusk T, Potts JD, Goodwin RL, Davis J, Hoffman S, Wen X, Sugi Y, Kern CB, Mjaatvedt CH, et al. Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues. Journal of Cellular Biochemistry. 101: 695-711. PMID 17226767 DOI: 10.1002/Jcb.21224  1
2006 Nesbitt T, Lemley A, Davis J, Yost MJ, Goodwin RL, Potts JD. Epicardial development in the rat: A new perspective Microscopy and Microanalysis. 12: 390-398. PMID 16984665 DOI: 10.1017/S1431927606060533  1
2006 Patel GK, Goodwin R, Chawla M, Laidler P, Price PE, Finlay AY, Motley RJ. Imiquimod 5% cream monotherapy for cutaneous squamous cell carcinoma in situ (Bowen's disease): A randomized, double-blind, placebo-controlled trial Journal of the American Academy of Dermatology. 54: 1025-1032. PMID 16713457 DOI: 10.1016/j.jaad.2006.01.055  1
2006 Goodwin RG, Kell WJ, Laidler P, Long CC, Whatley SD, McKinley M, Badminton MN, Burnett AK, Williams GT, Elder GH. Photosensitivity and acute liver injury in myeloproliferative disorder secondary to late-onset protoporphyria caused by deletion of a ferrochelatase gene in hematopoietic cells. Blood. 107: 60-2. PMID 16150949 DOI: 10.1182/blood-2004-12-4939  1
2005 Price MR, Baillie GL, Thomas A, Stevenson LA, Easson M, Goodwin R, McLean A, McIntosh L, Goodwin G, Walker G, Westwood P, Marrs J, Thomson F, Cowley P, Christopoulos A, et al. Allosteric modulation of the cannabinoid CB1 receptor. Molecular Pharmacology. 68: 1484-95. PMID 16113085 DOI: 10.1124/Mol.105.016162  1
2005 Dees E, Robertson JB, Ashe M, Pabón-Peña LM, Bader D, Goodwin RL. LEK1 protein expression in normal and dysregulated cardiomyocyte mitosis. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 286: 823-32. PMID 16047383 DOI: 10.1002/Ar.A.20221  1
2005 Baron SE, Goodwin RG, Nicolau N, Blackford S, Goulden V. Use of complementary medicine among outpatients with dermatologic conditions within Yorkshire and South Wales, United Kingdom. Journal of the American Academy of Dermatology. 52: 589-94. PMID 15793507 DOI: 10.1016/j.jaad.2004.11.058  0.01
2005 Goodwin RL, Nesbitt T, Price RL, Wells JC, Yost MJ, Potts JD. Three-dimensional model system of valvulogenesis Developmental Dynamics. 233: 122-129. PMID 15765508 DOI: 10.1002/Dvdy.20326  1
2005 Palin R, Barn DR, Clark JK, Cottney JE, Cowley PM, Crockatt M, Evans L, Feilden H, Goodwin RR, Griekspoor F, Grove SJ, Houghton AK, Jones PS, Morphy RJ, Smith AR, et al. Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists. Bioorganic & Medicinal Chemistry Letters. 15: 589-93. PMID 15664818 DOI: 10.1016/j.bmcl.2004.11.049  1
2004 Bellucci RJ, Zizmor J, Goodwin RE. Odontoma of the middle ear: a case presentation. 1975. Archives of Otolaryngology--Head & Neck Surgery. 130: 1225-7. PMID 15497214  0.01
2000 Simmons R, Fernandez JL, Goodwin R, Koenig S, O'Sullivan J. Lessons learned from Xavier Ieee Robotics & Automation Magazine. 7: 33-39. DOI: 10.1109/100.848266  1
1997 Simmons RG, Goodwin R, Haigh KZ, Koenig S, O'Sullivan J, Veloso MM. Xavier: experience with a layered robot architecture Intelligence\/Sigart Bulletin. 8: 22-33. DOI: 10.1145/272874.272878  1
1993 Goodwin R. Formalizing Properties of Agents Journal of Logic and Computation. 5: 763-781. DOI: 10.1093/Logcom/5.6.763  0.01
Show low-probability matches.