Matthias P. Lutolf - Publications

Affiliations: 
École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lorenzo-Martín LF, Hübscher T, Bowler AD, Broguiere N, Langer J, Tillard L, Nikolaev M, Radtke F, Lutolf MP. Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo. Nature. 629: 450-457. PMID 38658753 DOI: 10.1038/s41586-024-07330-2  0.651
2023 Girgin M, Broguiere N, Mattolini L, Lutolf M. A New Approach to Generate Gastruloids to Develop Anterior Neural Tissues. Bio-Protocol. 13: e4722. PMID 37497450 DOI: 10.21769/BioProtoc.4722  0.723
2022 Tischler J, Swank Z, Hsiung HA, Vianello S, Lutolf MP, Maerkl SJ. An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates. Cell Reports Methods. 2: 100244. PMID 35880022 DOI: 10.1016/j.crmeth.2022.100244  0.304
2022 Gonzalez DM, Schrode N, Ebrahim TAM, Broguiere N, Rossi G, Drakhlis L, Zweigerdt R, Lutolf MP, Beaumont KG, Sebra R, Dubois NC. Dissecting mechanisms of chamber-specific cardiac differentiation and its perturbation following retinoic acid exposure. Development (Cambridge, England). PMID 35686629 DOI: 10.1242/dev.200557  0.675
2021 Chrisnandy A, Blondel D, Rezakhani S, Broguiere N, Lutolf MP. Synthetic dynamic hydrogels promote degradation-independent in vitro organogenesis. Nature Materials. PMID 34782747 DOI: 10.1038/s41563-021-01136-7  0.714
2021 Girgin MU, Broguiere N, Hoehnel S, Brandenberg N, Mercier B, Arias AM, Lutolf MP. Bioengineered embryoids mimic post-implantation development in vitro. Nature Communications. 12: 5140. PMID 34446708 DOI: 10.1038/s41467-021-25237-8  0.712
2021 LeSavage BL, Suhar RA, Broguiere N, Lutolf MP, Heilshorn SC. Next-generation cancer organoids. Nature Materials. PMID 34385685 DOI: 10.1038/s41563-021-01057-5  0.652
2021 Rezakhani S, Gjorevski N, Lutolf MP. Extracellular matrix requirements for gastrointestinal organoid cultures. Biomaterials. 276: 121020. PMID 34280822 DOI: 10.1016/j.biomaterials.2021.121020  0.313
2021 Girgin MU, Broguiere N, Mattolini L, Lutolf MP. Gastruloids generated without exogenous Wnt activation develop anterior neural tissues. Stem Cell Reports. 16: 1143-1155. PMID 33891872 DOI: 10.1016/j.stemcr.2021.03.017  0.7
2020 Rossi G, Broguiere N, Miyamoto M, Boni A, Guiet R, Girgin M, Kelly RG, Kwon C, Lutolf MP. Capturing Cardiogenesis in Gastruloids. Cell Stem Cell. PMID 33176168 DOI: 10.1016/j.stem.2020.10.013  0.704
2020 Nikolaev M, Mitrofanova O, Broguiere N, Geraldo S, Dutta D, Tabata Y, Elci B, Brandenberg N, Kolotuev I, Gjorevski N, Clevers H, Lutolf MP. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. Nature. 585: 574-578. PMID 32939089 DOI: 10.1038/S41586-020-2724-8  0.716
2020 Broguiere N, Lüchtefeld I, Trachsel L, Mazunin D, Rizzo R, Bode JW, Lutolf MP, Zenobi-Wong M. Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices. Advanced Materials (Deerfield Beach, Fla.). e1908299. PMID 32390195 DOI: 10.1002/Adma.201908299  0.71
2020 Broguiere N, Lüchtefeld I, Trachsel L, Mazunin D, Rizzo R, Bode JW, Lutolf MP, Zenobi‐Wong M. Tissue Engineering: Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices (Adv. Mater. 25/2020) Advanced Materials. 32: 2070193. DOI: 10.1002/Adma.202070193  0.688
2019 Licht C, Rose J, Omidinia Anarkoli A, Blondel D, Roccio M, Haraszti T, Gehlen DB, Hubbell JA, Lutolf MP, De Laporte L. Synthetic 3D PEG-Anisogels tailored with fibronectin fragments induce aligned nerve extension. Biomacromolecules. PMID 31614080 DOI: 10.1021/Acs.Biomac.9B00891  0.47
2019 Ishihara J, Ishihara A, Starke RD, Peghaire CR, Smith KE, McKinnon TA, Tabata Y, Sasaki K, White MJ, Fukunaga K, Laffan MA, Lutolf MP, Randi AM, Hubbell JA. The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing. Blood. PMID 30975637 DOI: 10.1182/Blood.2019000510  0.421
2019 Vardar E, Vythilingam G, Pinnagoda K, Engelhardt EM, Zambelli PY, Hubbell JA, Lutolf MP, Frey P, Larsson HM. A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence. Biomaterials. 206: 41-48. PMID 30925287 DOI: 10.1016/J.Biomaterials.2019.03.030  0.415
2017 Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Pinnagoda K, Vythilingam G, Hubbell JA, Lutolf MP, Frey P. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomaterialia. 67: 156-166. PMID 29197579 DOI: 10.1016/J.Actbio.2017.11.034  0.493
2017 Gjorevski N, Lutolf MP. Synthesis and characterization of well-defined hydrogel matrices and their application to intestinal stem cell and organoid culture. Nature Protocols. 12: 2263-2274. PMID 28981121 DOI: 10.1038/Nprot.2017.095  0.37
2017 Ishihara K, Ranga A, Lutolf MP, Tanaka EM, Meinhardt A. Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1597: 43-55. PMID 28361309 DOI: 10.1007/978-1-4939-6949-4_4  0.338
2017 Tabata Y, Lutolf MP. Multiscale microenvironmental perturbation of pluripotent stem cell fate and self-organization. Scientific Reports. 7: 44711. PMID 28303935 DOI: 10.1038/srep44711  0.309
2016 Gjorevski N, Sachs N, Manfrin A, Giger S, Bragina ME, Ordóñez-Morán P, Clevers H, Lutolf MP. Designer matrices for intestinal stem cell and organoid culture. Nature. PMID 27851739 DOI: 10.1038/Nature20168  0.337
2016 Ranga A, Girgin M, Meinhardt A, Eberle D, Caiazzo M, Tanaka EM, Lutolf MP. Neural tube morphogenesis in synthetic 3D microenvironments. Proceedings of the National Academy of Sciences of the United States of America. PMID 27742791 DOI: 10.1073/pnas.1603529113  0.313
2016 Ranga A, Lutolf MP, Hilborn J, Ossipov DA. Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction. Biomacromolecules. 17: 1553-60. PMID 27014785 DOI: 10.1021/acs.biomac.5b01587  0.339
2015 Lienemann PS, Devaud YR, Reuten R, Simona BR, Karlsson M, Weber W, Koch M, Lutolf MP, Milleret V, Ehrbar M. Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 101-11. PMID 25385042 DOI: 10.1039/c4ib00152d  0.336
2014 Mosiewicz KA, Kolb L, van der Vlies AJ, Lutolf MP. Microscale patterning of hydrogel stiffness through light-triggered uncaging of thiols. Biomaterials Science. 2: 1640-1651. PMID 32481945 DOI: 10.1039/c4bm00262h  0.308
2014 Tabata Y, Horiguchi I, Lutolf MP, Sakai Y. Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors. Biomaterials Science. 2: 176-183. PMID 32481877 DOI: 10.1039/c3bm60183h  0.318
2014 Ranga A, Gobaa S, Okawa Y, Mosiewicz K, Negro A, Lutolf MP. 3D niche microarrays for systems-level analyses of cell fate. Nature Communications. 5: 4324. PMID 25027775 DOI: 10.1038/ncomms5324  0.309
2014 Gjorevski N, Ranga A, Lutolf MP. Bioengineering approaches to guide stem cell-based organogenesis. Development (Cambridge, England). 141: 1794-804. PMID 24757002 DOI: 10.1242/Dev.101048  0.368
2014 Cosson S, Lutolf MP. Hydrogel microfluidics for the patterning of pluripotent stem cells. Scientific Reports. 4: 4462. PMID 24662945 DOI: 10.1038/srep04462  0.304
2013 Mosiewicz KA, Kolb L, Van Der Vlies AJ, Martino MM, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP. In situ cell manipulation through enzymatic hydrogel photopatterning Nature Materials. 12: 1072-1078. PMID 24121990 DOI: 10.1038/Nmat3766  0.528
2013 Cosson S, Allazetta S, Lutolf MP. Patterning of cell-instructive hydrogels by hydrodynamic flow focusing. Lab On a Chip. 13: 2099-105. PMID 23598796 DOI: 10.1039/c3lc50219h  0.327
2013 Martino MM, Briquez PS, Ranga A, Lutolf MP, Hubbell JA. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix Proceedings of the National Academy of Sciences of the United States of America. 110: 4563-4568. PMID 23487783 DOI: 10.1073/Pnas.1221602110  0.432
2012 Larsson HM, Lee ST, Roccio M, Velluto D, Lutolf MP, Frey P, Hubbell JA. Sorting live stem cells based on Sox2 mRNA expression. Plos One. 7: e49874. PMID 23209609 DOI: 10.1371/Journal.Pone.0049874  0.467
2011 Sala A, Hänseler P, Ranga A, Lutolf MP, Vörös J, Ehrbar M, Weber FE. Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 1102-11. PMID 21986771 DOI: 10.1039/c1ib00045d  0.375
2010 Bott K, Upton Z, Schrobback K, Ehrbar M, Hubbell JA, Lutolf MP, Rizzi SC. The effect of matrix characteristics on fibroblast proliferation in 3D gels. Biomaterials. 31: 8454-64. PMID 20684983 DOI: 10.1016/J.Biomaterials.2010.07.046  0.511
2010 Mosiewicz KA, Johnsson K, Lutolf MP. Phosphopantetheinyl transferase-catalyzed formation of bioactive hydrogels for tissue engineering. Journal of the American Chemical Society. 132: 5972-4. PMID 20373804 DOI: 10.1021/Ja9098164  0.346
2010 Jo YS, Rizzi SC, Ehrbar M, Weber FE, Hubbell JA, Lutolf MP. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. Journal of Biomedical Materials Research. Part A. 93: 870-7. PMID 19701911 DOI: 10.1002/Jbm.A.32580  0.447
2010 Mosiewicz K, Johnsson K, Lutolf MP. PEG-based bioactive hydrogels crosslinked via phosphopantetheinyl transferase Mrs Proceedings. 1272. DOI: 10.1557/Proc-1272-Pp07-04  0.307
2009 Lutolf MP, Blau HM. Artificial stem cell niches. Advanced Materials (Deerfield Beach, Fla.). 21: 3255-68. PMID 20882496 DOI: 10.1002/Adma.200802582  0.302
2009 Lutolf MP. Integration column: artificial ECM: expanding the cell biology toolbox in 3D. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 235-41. PMID 20023734 DOI: 10.1039/b902243k  0.317
2009 Lutolf MP, Gilbert PM, Blau HM. Designing materials to direct stem-cell fate. Nature. 462: 433-41. PMID 19940913 DOI: 10.1038/Nature08602  0.318
2009 Jo YS, Gantz J, Hubbell JA, Lutolf MP. Tailoring hydrogel degradation and drug release via neighboring amino acid controlled ester hydrolysis Soft Matter. 5: 440-446. DOI: 10.1039/B814584A  0.425
2008 Cordey M, Limacher M, Kobel S, Taylor V, Lutolf MP. Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays. Stem Cells (Dayton, Ohio). 26: 2586-94. PMID 18669905 DOI: 10.1634/stemcells.2008-0498  0.31
2008 Kraehenbuehl TP, Zammaretti P, Van der Vlies AJ, Schoenmakers RG, Lutolf MP, Jaconi ME, Hubbell JA. Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel Biomaterials. 29: 2757-2766. PMID 18396331 DOI: 10.1016/J.Biomaterials.2008.03.016  0.512
2008 Raeber GP, Lutolf MP, Hubbell JA. Part II: Fibroblasts preferentially migrate in the direction of principal strain Biomechanics and Modeling in Mechanobiology. 7: 215-225. PMID 17619206 DOI: 10.1007/S10237-007-0090-1  0.403
2008 Ehrbar M, Lütolf MP, Rizzi SC, Hubbell JA, Weber FE. Artificial extracellular matrices for bone tissue engineering Bone. 42: S72. DOI: 10.1016/J.Bone.2007.12.131  0.405
2007 Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules. 8: 3000-7. PMID 17883273 DOI: 10.1021/Bm070228F  0.503
2007 Raeber GP, Lutolf MP, Hubbell JA. Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs Acta Biomaterialia. 3: 615-629. PMID 17572164 DOI: 10.1016/J.Actbio.2007.03.013  0.517
2007 Ehrbar M, Rizzi SC, Hlushchuk R, Djonov V, Zisch AH, Hubbell JA, Weber FE, Lutolf MP. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering Biomaterials. 28: 3856-3866. PMID 17568666 DOI: 10.1016/J.Biomaterials.2007.03.027  0.54
2005 Raeber GP, Lutolf MP, Hubbell JA. Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration. Biophysical Journal. 89: 1374-88. PMID 15923238 DOI: 10.1529/Biophysj.104.050682  0.465
2005 Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nature Biotechnology. 23: 47-55. PMID 15637621 DOI: 10.1038/Nbt1055  0.555
2005 Fittkau MH, Zilla P, Bezuidenhout D, Lutolf MP, Human P, Hubbell JA, Davies N. The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides Biomaterials. 26: 167-174. PMID 15207463 DOI: 10.1016/J.Biomaterials.2004.02.012  0.442
2004 Park Y, Lutolf MP, Hubbell JA, Hunziker EB, Wong M. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Engineering. 10: 515-22. PMID 15165468 DOI: 10.1089/107632704323061870  0.467
2004 Zisch AH, Lutolf MP, Hubbell JA. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 12: 295-310. PMID 14630296 DOI: 10.1016/S1054-8807(03)00089-9  0.469
2004 Lutolf MP, Hubbell JA. Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition. Biomacromolecules. 4: 713-22. PMID 12741789 DOI: 10.1021/Bm025744E  0.414
2003 Zisch AH, Lutolf MP, Ehrbar M, Raeber GP, Rizzi SC, Davies N, Schmökel H, Bezuidenhout D, Djonov V, Zilla P, Hubbell JA. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth Faseb Journal. 17: 2260-2262. PMID 14563693 DOI: 10.1096/Fj.02-1041Fje  0.491
2003 Lutolf MP, Weber FE, Schmoekel HG, Schense JC, Kohler T, Müller R, Hubbell JA. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nature Biotechnology. 21: 513-8. PMID 12704396 DOI: 10.1038/Nbt818  0.469
2003 Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB, Hubbell JA. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proceedings of the National Academy of Sciences of the United States of America. 100: 5413-8. PMID 12686696 DOI: 10.1073/Pnas.0737381100  0.502
2003 Lutolf M, Raeber G, Zisch A, Tirelli N, Hubbell J. Cell-Responsive Synthetic Hydrogels Advanced Materials. 15: 888-892. DOI: 10.1002/Adma.200304621  0.497
2002 Tirelli N, Lutolf MP, Napoli A, Hubbell JA. Poly(ethylene glycol) block copolymers. Journal of Biotechnology. 90: 3-15. PMID 12069046 DOI: 10.1016/S1389-0352(01)00057-5  0.409
2001 Lutolf MP, Tirelli N, Cerritelli S, Cavalli L, Hubbell JA. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjugate Chemistry. 12: 1051-6. PMID 11716699 DOI: 10.1021/Bc015519E  0.374
2001 Elbert DL, Pratt AB, Lutolf MP, Halstenberg S, Hubbell JA. Protein delivery from materials formed by self-selective conjugate addition reactions. Journal of Controlled Release : Official Journal of the Controlled Release Society. 76: 11-25. PMID 11532309 DOI: 10.1016/S0168-3659(01)00398-4  0.644
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