| Year |
Citation |
Score |
| 2023 |
Zhang Y, Zhao X, Shen B, Bai Y, Chang C, Stojanovic A, Wang C, Mack A, Deng G, Skidgel RA, Cheng N, Du X. Integrin β directly inhibits the Gα-p115RhoGEF interaction to regulate G protein signaling and platelet exocytosis. Nature Communications. 14: 4966. PMID 37587112 DOI: 10.1038/s41467-023-40531-3 |
0.493 |
|
| 2022 |
Zhang Y, Ehrlich SM, Zhu C, Du X. Signaling mechanisms of the platelet glycoprotein Ib-IX complex. Platelets. 1-10. PMID 35615944 DOI: 10.1080/09537104.2022.2071852 |
0.465 |
|
| 2021 |
Chang CW, Cheng N, Bai Y, Skidgel RA, Du X. Gα Mediates Transendothelial Migration of Neutrophils by Promoting Integrin-Dependent Motility without Affecting Directionality. Journal of Immunology (Baltimore, Md. : 1950). PMID 34799423 DOI: 10.4049/jimmunol.2001385 |
0.421 |
|
| 2021 |
Xu Z, Liang Y, Delaney MK, Zhang Y, Kim K, Li J, Bai Y, Cho J, Ushio-Fukai M, Cheng N, Du X. Shear and Integrin Outside-In Signaling Activates NADPH-Oxidase 2 to Promote Platelet Activation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315773. PMID 33691478 DOI: 10.1161/ATVBAHA.120.315773 |
0.424 |
|
| 2018 |
Li J, Kim K, Jeong SY, Chiu J, Xiong B, Petukhov PA, Dai X, Li X, Andrews RK, Du X, Hogg PJ, Cho J. Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions. Circulation. PMID 30586735 DOI: 10.1161/Circulationaha.118.036323 |
0.391 |
|
| 2018 |
Pang A, Cui Y, Chen Y, Cheng N, Delaney MK, Gu M, Stojanovic-Terpo A, Zhu C, Du X. Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release and coagulation. Blood. PMID 29853537 DOI: 10.1182/Blood-2017-05-785253 |
0.44 |
|
| 2018 |
Stritt S, Birkholz I, Beck S, Sorrentino S, Sapra KT, Viaud J, Heck J, Gaits-Iacovoni F, Schulze H, Du X, Hartwig JH, Braun A, Bender M, Medalia O, Nieswandt B. Profilin 1-mediated cytoskeletal rearrangements regulate integrin function in mouse platelets. Blood Advances. 2: 1040-1045. PMID 29739775 DOI: 10.1182/Bloodadvances.2017014001 |
0.346 |
|
| 2018 |
Chen Y, Ruggeri ZM, Du X. 14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling. Blood. PMID 29622550 DOI: 10.1182/blood-2017-09-742650 |
0.473 |
|
| 2017 |
Stritt S, Beck S, Becker IC, Vögtle T, Hakala M, Heinze KG, Du X, Bender M, Braun A, Lappalainen P, Nieswandt B. Twinfilin 2a is a regulator of platelet reactivity and turnover in mice. Blood. PMID 28743718 DOI: 10.1182/blood-2017-02-770768 |
0.367 |
|
| 2017 |
Estevez B, Du X. New Concepts and Mechanisms of Platelet Activation Signaling. Physiology (Bethesda, Md.). 32: 162-177. PMID 28228483 DOI: 10.1152/physiol.00020.2016 |
0.438 |
|
| 2016 |
Delaney MK, Kim K, Estevez B, Xu Z, Stojanovic-Terpo A, Shen B, Ushio-Fukai M, Cho J, Du X. Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26988594 DOI: 10.1161/Atvbaha.116.307308 |
0.407 |
|
| 2015 |
Estevez B, Kim K, Delaney MK, Stojanovic-Terpo A, Shen B, Ruan C, Cho J, Ruggeri ZM, Du X. Signaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activation. Blood. PMID 26585954 DOI: 10.1182/Blood-2015-04-638387 |
0.51 |
|
| 2015 |
Shen B, Estevez B, Xu Z, Kreutz B, Karginov A, Bai Y, Qian F, Norifumi U, Mosher D, Du X. The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA. Molecular Biology of the Cell. PMID 26310447 DOI: 10.1091/Mbc.E15-05-0274 |
0.428 |
|
| 2014 |
Estevez B, Shen B, Du X. Targeting integrin and integrin signaling in treating thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 24-9. PMID 25256236 DOI: 10.1161/ATVBAHA.114.303411 |
0.429 |
|
| 2014 |
Delaney MK, Liu J, Kim K, Shen B, Stojanovic-Terpo A, Zheng Y, Cho J, Du X. Agonist-induced platelet procoagulant activity requires shear and a Rac1-dependent signaling mechanism. Blood. 124: 1957-67. PMID 25079357 DOI: 10.1182/Blood-2014-03-560821 |
0.46 |
|
| 2014 |
Li J, Kim K, Hahm E, Molokie R, Hay N, Gordeuk VR, Du X, Cho J. Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. The Journal of Clinical Investigation. 124: 1483-96. PMID 24642468 DOI: 10.1172/Jci72305 |
0.373 |
|
| 2013 |
Shen B, Zhao X, O'Brien KA, Stojanovic-Terpo A, Delaney MK, Kim K, Cho J, Lam SC, Du X. A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature. 503: 131-5. PMID 24162846 DOI: 10.1038/Nature12613 |
0.481 |
|
| 2013 |
Yin H, Stojanovic-Terpo A, Xu W, Corken A, Zakharov A, Qian F, Pavlovic S, Krbanjevic A, Lyubimov AV, Wang ZJ, Ware J, Du X. Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2529-37. PMID 24051142 DOI: 10.1161/ATVBAHA.113.302339 |
0.339 |
|
| 2013 |
Estevez B, Stojanovic-Terpo A, Delaney MK, O'Brien KA, Berndt MC, Ruan C, Du X. LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood. 121: 4586-94. PMID 23620575 DOI: 10.1182/blood-2012-12-470765 |
0.366 |
|
| 2012 |
Delaney MK, Liu J, Zheng Y, Berndt MC, Du X. The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2761-8. PMID 22995516 DOI: 10.1161/ATVBAHA.112.254920 |
0.448 |
|
| 2012 |
Shen B, Delaney MK, Du X. Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction. Current Opinion in Cell Biology. 24: 600-6. PMID 22980731 DOI: 10.1016/j.ceb.2012.08.011 |
0.46 |
|
| 2012 |
O'Brien KA, Gartner TK, Hay N, Du X. ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2232-40. PMID 22814751 DOI: 10.1161/Atvbaha.112.254680 |
0.419 |
|
| 2011 |
O'Brien KA, Stojanovic-Terpo A, Hay N, Du X. An important role for Akt3 in platelet activation and thrombosis. Blood. 118: 4215-23. PMID 21821713 DOI: 10.1182/Blood-2010-12-323204 |
0.385 |
|
| 2011 |
Zhang G, Xiang B, Dong A, Skoda RC, Daugherty A, Smyth SS, Du X, Li Z. Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood. 118: 3670-9. PMID 21803853 DOI: 10.1182/Blood-2011-03-341107 |
0.363 |
|
| 2010 |
Li Z, Delaney MK, O'Brien KA, Du X. Signaling during platelet adhesion and activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2341-9. PMID 21071698 DOI: 10.1161/ATVBAHA.110.207522 |
0.485 |
|
| 2010 |
Li Z, Zhang G, Liu J, Stojanovic A, Ruan C, Lowell CA, Du X. An important role of the SRC family kinase Lyn in stimulating platelet granule secretion. The Journal of Biological Chemistry. 285: 12559-70. PMID 20189992 DOI: 10.1074/Jbc.M109.098756 |
0.374 |
|
| 2010 |
Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, Kozasa T, Du X. G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling. Science (New York, N.Y.). 327: 340-3. PMID 20075254 DOI: 10.1126/Science.1174779 |
0.474 |
|
| 2009 |
Zhang G, Han J, Welch EJ, Ye RD, Voyno-Yasenetskaya TA, Malik AB, Du X, Li Z. Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. Journal of Immunology (Baltimore, Md. : 1950). 182: 7997-8004. PMID 19494325 DOI: 10.4049/Jimmunol.0802884 |
0.31 |
|
| 2009 |
Welch EJ, Naikawadi RP, Li Z, Lin P, Ishii S, Shimizu T, Tiruppathi C, Du X, Subbaiah PV, Ye RD. Opposing effects of platelet-activating factor and lyso-platelet-activating factor on neutrophil and platelet activation. Molecular Pharmacology. 75: 227-34. PMID 18931035 DOI: 10.1124/Mol.108.051003 |
0.404 |
|
| 2008 |
Flevaris P, Li Z, Zhang G, Zheng Y, Liu J, Du X. Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood. 113: 893-901. PMID 18957688 DOI: 10.1182/blood-2008-05-155978 |
0.414 |
|
| 2008 |
Marjanovic JA, Stojanovic A, Brovkovych VM, Skidgel RA, Du X. Signaling-mediated functional activation of inducible nitric-oxide synthase and its role in stimulating platelet activation. The Journal of Biological Chemistry. 283: 28827-34. PMID 18753139 DOI: 10.1074/jbc.M801646200 |
0.345 |
|
| 2008 |
Yin H, Liu J, Li Z, Berndt MC, Lowell CA, Du X. Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. Blood. 112: 1139-46. PMID 18550847 DOI: 10.1182/Blood-2008-02-140970 |
0.441 |
|
| 2008 |
Su X, Mi J, Yan J, Flevaris P, Lu Y, Liu H, Ruan Z, Wang X, Kieffer N, Chen S, Du X, Xi X. RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase. Blood. 112: 592-602. PMID 18398066 DOI: 10.1182/blood-2007-09-110437 |
0.333 |
|
| 2008 |
Yin H, Stojanovic A, Hay N, Du X. The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation. Blood. 111: 658-65. PMID 17914025 DOI: 10.1182/Blood-2007-04-085514 |
0.443 |
|
| 2007 |
Du X. Signaling and regulation of the platelet glycoprotein Ib-IX-V complex Current Opinion in Hematology. 14: 262-269. PMID 17414217 DOI: 10.1097/MOH.0b013e3280dce51a |
0.402 |
|
| 2006 |
Stojanovic A, Marjanovic JA, Brovkovych VM, Peng X, Hay N, Skidgel RA, Du X. A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation. The Journal of Biological Chemistry. 281: 16333-9. PMID 16613861 DOI: 10.1074/Jbc.M512378200 |
0.389 |
|
| 2005 |
Li Z, Zhang G, Feil R, Han J, Du X. Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood. 107: 965-72. PMID 16210341 DOI: 10.1182/blood-2005-03-1308 |
0.384 |
|
| 2005 |
Dai K, Bodnar R, Berndt MC, Du X. A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood. 106: 1975-81. PMID 15941906 DOI: 10.1182/BLOOD-2005-01-0440 |
0.396 |
|
| 2004 |
Li Z, Zhang G, Marjanovic JA, Ruan C, Du X. A platelet secretion pathway mediated by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 279: 42469-75. PMID 15280395 DOI: 10.1074/jbc.M401532200 |
0.326 |
|
| 2004 |
Du X, Marjanovic JA, Li Z. On the roles of cGMP and glycoprotein Ib in platelet activation. Blood. 103: 4371-2; author reply. PMID 15155473 DOI: 10.1182/blood-2004-02-0507 |
0.342 |
|
| 2003 |
Li Z, Zhang G, Le Breton GC, Gao X, Malik AB, Du X. Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. The Journal of Biological Chemistry. 278: 30725-31. PMID 12796499 DOI: 10.1074/jbc.M301838200 |
0.333 |
|
| 2003 |
Li Z, Ajdic J, Eigenthaler M, Du X. A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans. Blood. 101: 4423-9. PMID 12576312 DOI: 10.1182/blood-2002-10-3210 |
0.325 |
|
| 2003 |
Li Z, Xi X, Gu M, Feil R, Ye RD, Eigenthaler M, Hofmann F, Du X. A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell. 112: 77-86. PMID 12526795 DOI: 10.1016/S0092-8674(02)01254-0 |
0.379 |
|
| 2002 |
Bodnar RJ, Xi X, Li Z, Berndt MC, Du X. Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta). The Journal of Biological Chemistry. 277: 47080-7. PMID 12361948 DOI: 10.1074/jbc.M208329200 |
0.358 |
|
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