Amanda J. Mikels, Ph.D.
Affiliations: | 2007 | Stanford University, Palo Alto, CA |
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"Amanda Mikels"Parents
Sign in to add mentor| Roel Nusse | grad student | 2007 | Stanford | |
| (One signal, two pathways: Analysis of how a single Wnt ligand can initiate discrete signaling pathways through the activation of two distinct receptors.) | ||||
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Publications
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| Edris B, Espinosa I, Mühlenberg T, et al. (2012) ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. The Journal of Pathology. 227: 223-33 |
| Carlson ME, Conboy MJ, Hsu M, et al. (2009) Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses. Aging Cell. 8: 676-89 |
| Mikels A, Minami Y, Nusse R. (2009) Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. The Journal of Biological Chemistry. 284: 30167-76 |
| Wright TM, Brannon AR, Gordan JD, et al. (2009) Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma. Oncogene. 28: 2513-23 |
| Marston DJ, Roh M, Mikels AJ, et al. (2008) Wnt signaling during Caenorhabditis elegans embryonic development. Methods in Molecular Biology (Clifton, N.J.). 469: 103-11 |
| van Amerongen R, Mikels A, Nusse R. (2008) Alternative wnt signaling is initiated by distinct receptors. Science Signaling. 1: re9 |
| Rinn JL, Wang JK, Allen N, et al. (2008) A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes & Development. 22: 303-7 |
| Mikels AJ, Nusse R. (2006) Wnts as ligands: processing, secretion and reception. Oncogene. 25: 7461-8 |
| Mikels AJ, Nusse R. (2006) Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. Plos Biology. 4: e115 |