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Zhi Xu, Ph.D.

Affiliations: 
2008 University of Notre Dame, Notre Dame, IN, United States 
Area:
blood coagulation and blood clot dissolution
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"Zhi Xu"
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Francis J. Castellino grad student 2008 Notre Dame
 (Dissection of the multiple functions of Plasminogen Activator Inhibitor-1.)

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Publications

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Gupta KK, Xu Z, Castellino FJ, et al. (2016) Plasminogen activator inhibitor-1 stimulates macrophage activation through toll-like receptor-4. Biochemical and Biophysical Research Communications
Narasaki R, Xu Z, Liang Z, et al. (2012) The vitronectin-binding domain of plasminogen activator inhibitor-1 plays an important functional role in lipopolysaccharide-induced lethality in mice. Journal of Thrombosis and Haemostasis : Jth. 10: 2618-21
Iwaki T, Malinverno C, Smith D, et al. (2010) The generation and characterization of mice expressing a plasmin-inactivating active site mutation. Journal of Thrombosis and Haemostasis : Jth. 8: 2341-4
Xu Z, Xu H, Ploplis VA, et al. (2010) Factor VII deficiency impairs cutaneous wound healing in mice. Molecular Medicine (Cambridge, Mass.). 16: 167-76
Xu Z, Castellino FJ, Ploplis VA. (2010) Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture. Blood. 115: 2038-47
Balsara RD, Xu Z, Ploplis VA. (2007) Targeting plasminogen activator inhibitor-1: role in cell signaling and the biology of domain-specific knock-in mice. Current Drug Targets. 8: 982-95
Kwak SH, Wang XQ, He Q, et al. (2006) Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway. Thrombosis and Haemostasis. 95: 829-35
Xu Z, Balsara RD, Gorlatova NV, et al. (2004) Conservation of critical functional domains in murine plasminogen activator inhibitor-1. The Journal of Biological Chemistry. 279: 17914-20
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