Laura B. Peterson, Ph.D.

Affiliations: 
2012 Medicinal Chemistry University of Kansas, Lawrence, KS, United States 
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Brian Blagg grad student 2012 University of Kansas
 (Investigation of the Hsp90 C-terminal Binding Site, Novel Inhibitors and Isoform-Dependent Client Proteins.)
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Patwardhan CA, Peterson LB, Blagg B, et al. (2014) Abstract 3197: Gedunin inactivates the co-chaperone p23 causing cancer cell death by apoptosis Cancer Research. 74: 3197-3197
Patwardhan CA, Fauq A, Peterson LB, et al. (2013) Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis. The Journal of Biological Chemistry. 288: 7313-25
Ghosh S, Peterson LB, Vielhauer G, et al. (2013) Abstract A16: Role of Hsp90alpha-1, a splice variant of Hsp90alpha, in cancer Cancer Research. 73
Zhao H, Yan B, Peterson LB, et al. (2012) 3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition. Acs Medicinal Chemistry Letters. 3: 327-331
Kusuma BR, Zhang L, Sundstrom T, et al. (2012) Synthesis and evaluation of novologues as C-terminal Hsp90 inhibitors with cytoprotective activity against sensory neuron glucotoxicity. Journal of Medicinal Chemistry. 55: 5797-812
Duerfeldt AS, Peterson LB, Maynard JC, et al. (2012) Development of a Grp94 inhibitor. Journal of the American Chemical Society. 134: 9796-804
Peterson LB, Eskew JD, Vielhauer GA, et al. (2012) The hERG channel is dependent upon the Hsp90α isoform for maturation and trafficking. Molecular Pharmaceutics. 9: 1841-6
Kusuma BR, Peterson LB, Zhao H, et al. (2011) Targeting the heat shock protein 90 dimer with dimeric inhibitors. Journal of Medicinal Chemistry. 54: 6234-53
Matts RL, Dixit A, Peterson LB, et al. (2011) Elucidation of the Hsp90 C-terminal inhibitor binding site. Acs Chemical Biology. 6: 800-7
Davenport J, Manjarrez JR, Peterson L, et al. (2011) Gambogic acid, a natural product inhibitor of Hsp90. Journal of Natural Products. 74: 1085-92
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