Daniel T. Sweet, Ph.D.

Affiliations: 
2012 Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cell Biology, Physiology Biology, Genetics
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"Daniel Sweet"

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Eleni Tzima grad student 2012 UNC Chapel Hill
 (The adaptor protein Shc is a critical regulator of angiogenic and shear stress signaling in endothelial cells.)
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Publications

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Hall JD, Farzaneh S, Babakhani Galangashi R, et al. (2022) Lymphoedema conditions disrupt endothelial barrier function . Journal of the Royal Society, Interface. 19: 20220223
Mehta V, Pang KL, Givens CS, et al. (2021) Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway. Science Advances. 7
Pujari A, Smith AF, Hall JD, et al. (2020) Lymphatic Valves Bifurcate Lymph Flow Into a Central Jet and a Slow-Moving Peri-Valvular Milieu. Journal of Biomechanical Engineering
Nonomura K, Lukacs V, Sweet DT, et al. (2018) Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation. Proceedings of the National Academy of Sciences of the United States of America. 115: 12817-12822
Sweet DT, Hall JD, Welsh J, et al. (2018) Investigating Effects of Fluid Shear Stress on Lymphatic Endothelial Cells. Methods in Molecular Biology (Clifton, N.J.). 1846: 213-227
Welsh JD, Kahn ML, Sweet DT. (2016) Lymphovenous hemostasis and the role of platelets in regulating lymphatic flow and lymphatic vessel maturation. Blood
Sweet DT, Jiménez JM, Chang J, et al. (2015) Lymph flow regulates collecting lymphatic vessel maturation in vivo. The Journal of Clinical Investigation. 125: 2995-3007
Hess PR, Rawnsley DR, Jakus Z, et al. (2014) Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. The Journal of Clinical Investigation. 124: 273-84
Sweet DT, Chen Z, Givens CS, et al. (2013) Endothelial Shc regulates arteriogenesis through dual control of arterial specification and inflammation via the notch and nuclear factor-κ-light-chain-enhancer of activated B-cell pathways. Circulation Research. 113: 32-9
Pi X, Lockyer P, Dyer LA, et al. (2012) Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2214-22
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