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Tadhg P. Begley, Ph.D.

Affiliations: 
Chemistry Texas A & M University, College Station, TX, United States 
Area:
Barton Professor of Chemistry
Website:
http://www.chem.tamu.edu/rgroup/begley/Principal%20Investigator.htm
Google:
"Tadhg Begley"
Bio:

http://www.science.tamu.edu/news/story.php?story_ID=1468#.V7Qd_49OLDc
http://resolver.caltech.edu/CaltechTHESIS:10202010-084119498

Mean distance: 7.34
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Parents

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Peter B. Dervan grad student 1982 Caltech
 (Bispecific, cleavable, protein DNA cross-linker, psoralen-diol-nitroveratrole. A probe of bacteriophage structure)
Wolfgang Oppolzer post-doc Université de Genève
Christopher T. Walsh post-doc MIT

Children

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Robert Aversa research assistant 2002-2006 Cornell
Neil  L. Kelleher grad student Cornell
Cynthia L. Kinsland grad student 2000 Cornell
Ryan A. Mehl grad student 2001 Cornell
Jason J. Reddick grad student 2001 Cornell
Ying Ge grad student 2002 Cornell
Jun Xi grad student 2002 Cornell
Erick Strauss grad student 2003 Cornell
Pieter C. Dorrestein grad student 2004 Cornell
Brian G. Lawhorn grad student 2004 Cornell
Huili Zhai grad student 2005 Cornell
Kristin E. Burns grad student 2006 Cornell
Amy M. Godert grad student 2006 Cornell
Amy L. Jenkins grad student 2007 Cornell
Jennie M. Sanders grad student 2008 Cornell
Abhishek Chatterjee grad student 2009 Cornell
Tathagata Mukherjee grad student 2009 Cornell
Kalyanaraman Krishnamoorthy grad student 2010 Cornell
Sean O'Leary grad student 2010 Cornell
Amrita B. Hazra grad student 2005-2010 Cornell
Nilkamal Mahanta grad student 2009-2015 Texas A & M
Angad P. Mehta grad student 2009-2015 Texas A & M
Lisa E. Cooper post-doc 2009- Texas A & M

Collaborators

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BETA: Related publications

Publications

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Hazra S, Begley TP. (2023) Alkylcysteine Sulfoxide C-S Monooxygenase Uses a Flavin-Dependent Pummerer Rearrangement. Journal of the American Chemical Society
Mondal A, Lai RY, Fedoseyenko D, et al. (2023) Oxidative Dearomatization of PLP in Thiamin Pyrimidine Biosynthesis in . Journal of the American Chemical Society
Lai RY, Mondal A, Fedoseyenko D, et al. (2022) Mechanistic Studies on the Single-Turnover Yeast Thiamin Pyrimidine Synthase: Characterization of the Inactive Enzyme. Journal of the American Chemical Society. 144: 10711-10717
Hazra S, Bhandari DM, Krishnamoorthy K, et al. (2022) Cysteine Dealkylation in by a Novel Flavin-Dependent Monooxygenase. Biochemistry
Rodrigues MJ, Giri N, Royant A, et al. (2021) Trapping and structural characterisation of a covalent intermediate in vitamin B biosynthesis catalysed by the Pdx1 PLP synthase. Rsc Chemical Biology. 3: 227-230
Joshi S, Fedoseyenko D, Sharma V, et al. (2021) Menaquinone Biosynthesis: New Strategies to Trap Radical Intermediates in the MqnE-Catalyzed Reaction. Biochemistry
Rabe von Pappenheim F, Aldeghi M, Shome B, et al. (2020) Structural basis for antibiotic action of the B antivitamin 2'-methoxy-thiamine. Nature Chemical Biology
Tao L, Pattenaude SA, Joshi S, et al. (2020) The radical SAM enzyme HydE generates adenosylated Fe(I) intermediates en route to the [FeFe]-hydrogenase catalytic H-cluster. Journal of the American Chemical Society
Wang Y, Begley TP. (2020) Mechanistic studies on CysS - a Vitamin B-dependent radical SAM methyltransferase involved in the biosynthesis of the -butyl group of cystobactamid. Journal of the American Chemical Society
Sayler RI, Stich TA, Joshi S, et al. (2019) Trapping and Electron Paramagnetic Resonance Characterization of the 5'dAdo Radical in a Radical -Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate. Acs Central Science. 5: 1777-1785
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