Ian Collins
Affiliations: | The Institute of Cancer Research |
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| Saint-Dizier F, Matthews TP, Gregson AM, et al. (2023) Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes. Journal of Medicinal Chemistry |
| Miller DSJ, Voell SA, Sosič I, et al. (2022) Encoding BRAF inhibitor functions in protein degraders. Rsc Medicinal Chemistry. 13: 731-736 |
| Pal A, Asad Y, Ruddle R, et al. (2020) Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation. Metabolomics : Official Journal of the Metabolomic Society. 16: 50 |
| Rogers RF, Walton MI, Cherry DL, et al. (2020) CHK1 inhibition is synthetically lethal with loss of B-family DNA polymerase function in human lung and colorectal cancer cells. Cancer Research |
| Pollock K, Liu M, Zaleska M, et al. (2019) Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase. Scientific Reports. 9: 19130 |
| Prevet H, Collins I. (2019) Labelled chemical probes for demonstrating direct target engagement in living systems. Future Medicinal Chemistry. 11: 1195-1224 |
| Chopra R, Sadok A, Collins I. (2019) A critical evaluation of the approaches to targeted protein degradation for drug discovery. Drug Discovery Today. Technologies. 31: 5-13 |
| Zaleska M, Pollock K, Collins I, et al. (2019) Solution NMR assignment of the ARC4 domain of human tankyrase 2. Biomolecular Nmr Assignments |
| Colombano G, Caldwell JJ, Matthews TP, et al. (2019) Binding to an unusual inactive kinase conformation by highly selective inhibitors of inositol-requiring enzyme 1α kinase-endoribonuclease. Journal of Medicinal Chemistry |
| Sharp SY, Chessum NE, Caldwell JJ, et al. (2018) Abstract 2976: Confirmation of in-cell target engagement using the proteolysis targeting chimeras (PROTACs) against pirin Cancer Research. 78: 2976-2976 |