Lyle W. Ostrow - Publications

Affiliations: 
2005 State University of New York, Buffalo, Buffalo, NY, United States 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yusuf IO, Parsi S, Ostrow LW, Brown RH, Thompson PR, Xu Z. PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS. Neurobiology of Disease. 106414. PMID 38253209 DOI: 10.1016/j.nbd.2024.106414  0.348
2023 Tsioras K, Smith KC, Edassery SL, Garjani M, Li Y, Williams C, McKenna ED, Guo W, Wilen AP, Hark TJ, Marklund SL, Ostrow LW, Gilthorpe JD, Ichida JK, Kalb RG, et al. Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis. Cell Reports. 113160. PMID 37776851 DOI: 10.1016/j.celrep.2023.113160  0.334
2019 Tam OH, Rozhkov NV, Shaw R, Kim D, Hubbard I, Fennessey S, Propp N, Fagegaltier D, Harris BT, Ostrow LW, Phatnani H, Ravits J, Dubnau J, Gale Hammell M. Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia. Cell Reports. 29: 1164-1177.e5. PMID 31665631 DOI: 10.1016/J.Celrep.2019.09.066  0.414
2018 Pereira GC, Sanchez L, Schaughency PM, Rubio-Roldán A, Choi JA, Planet E, Batra R, Turelli P, Trono D, Ostrow LW, Ravits J, Kazazian HH, Wheelan SJ, Heras SR, Mayer J, et al. Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis. Mobile Dna. 9: 35. PMID 30564290 DOI: 10.1186/S13100-018-0138-Z  0.404
2018 Mayer J, Harz C, Sanchez L, Pereira GC, Maldener E, Heras SR, Ostrow LW, Ravits J, Batra R, Meese E, García-Pérez JL, Goodier JL. Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins. Molecular Neurodegeneration. 13: 39. PMID 30068350 DOI: 10.1186/S13024-018-0275-3  0.399
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Ostrow LW, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027  0.385
2016 Ayers JI, Diamond J, Sari A, Fromholt S, Galaleldeen A, Ostrow LW, Glass JD, Hart PJ, Borchelt DR. Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS. Acta Neuropathologica. PMID 27704280 DOI: 10.1007/S00401-016-1623-4  0.395
2015 Jablonski AM, Lamitina T, Liachko NF, Sabatella M, Lu J, Zhang L, Ostrow LW, Gupta P, Wu CY, Doshi S, Mojsilovic-Petrovic J, Lans H, Wang J, Kraemer B, Kalb RG. Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14286-306. PMID 26490867 DOI: 10.1523/Jneurosci.0642-15.2015  0.323
2015 Li W, Lee MH, Henderson L, Tyagi R, Bachani M, Steiner J, Campanac E, Hoffman DA, von Geldern G, Johnson K, Maric D, Morris HD, Lentz M, Pak K, Mammen A, ... Ostrow L, et al. Human endogenous retrovirus-K contributes to motor neuron disease. Science Translational Medicine. 7: 307ra153. PMID 26424568 DOI: 10.1126/Scitranslmed.Aac8201  0.37
2015 Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, Daley EL, Miller SJ, Cunningham KM, Vidensky S, Gupta S, Thomas MA, Hong I, Chiu SL, Huganir RL, ... Ostrow LW, et al. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 525: 56-61. PMID 26308891 DOI: 10.1038/Nature14973  0.401
2013 Zu T, Liu Y, Bañez-Coronel M, Reid T, Pletnikova O, Lewis J, Miller TM, Harms MB, Falchook AE, Subramony SH, Ostrow LW, Rothstein JD, Troncoso JC, Ranum LP. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. 110: E4968-77. PMID 24248382 DOI: 10.1073/Pnas.1315438110  0.413
2013 Kang SH, Li Y, Fukaya M, Lorenzini I, Cleveland DW, Ostrow LW, Rothstein JD, Bergles DE. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nature Neuroscience. 16: 571-9. PMID 23542689 DOI: 10.1038/Nn.3357  0.401
2013 Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, et al. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. The Lancet. Neurology. 12: 435-42. PMID 23541756 DOI: 10.1016/S1474-4422(13)70061-9  0.301
2012 Bedlack R, Hardiman O, Heiman-Patterson T, Gutmann L, Bromberg M, Ostrow L, Carter G, Kabashi E, Bertorini T, Mozaffar T, Andersen P, Dietz J, Gamez J, Dimachkie M, Wang Y, et al. ALS untangled no. 17: "When ALS Is Lyme" Amyotrophic Lateral Sclerosis. 13: 487-491. PMID 22873562 DOI: 10.3109/17482968.2012.717796  0.303
2011 Ostrow LW, Suchyna TM, Sachs F. Stretch induced endothelin-1 secretion by adult rat astrocytes involves calcium influx via stretch-activated ion channels (SACs). Biochemical and Biophysical Research Communications. 410: 81-6. PMID 21640709 DOI: 10.1016/J.Bbrc.2011.05.109  0.553
2005 Ostrow LW, Sachs F. Mechanosensation and endothelin in astrocytes--hypothetical roles in CNS pathophysiology. Brain Research. Brain Research Reviews. 48: 488-508. PMID 15914254 DOI: 10.1016/J.Brainresrev.2004.09.005  0.562
2004 Gottlieb PA, Suchyna TM, Ostrow LW, Sachs F. Mechanosensitive ion channels as drug targets. Current Drug Targets. Cns and Neurological Disorders. 3: 287-95. PMID 15379605 DOI: 10.2174/1568007043337283  0.458
2000 Ostrow LW, Langan TJ, Sachs F. Stretch-induced endothelin-1 production by astrocytes. Journal of Cardiovascular Pharmacology. 36: S274-7. PMID 11078397 DOI: 10.1097/00005344-200036051-00081  0.553
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