Charles L. Howe, Ph.D. - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
neurodegneration, Down syndrome

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Clarkson BDS, Patel MS, LaFrance-Corey RG, Howe CL. Retrograde interferon-gamma signaling induces major histocompatibility class I expression in human-induced pluripotent stem cell-derived neurons. Annals of Clinical and Translational Neurology. 5: 172-185. PMID 29468178 DOI: 10.1002/Acn3.516  0.374
2017 Howe CL, LaFrance-Corey RG, Goddery EN, Johnson RK, Mirchia K. Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection. Journal of Neuroinflammation. 14: 238. PMID 29202854 DOI: 10.1186/S12974-017-1015-2  0.334
2017 Clarkson BDS, Kahoud RJ, McCarthy CB, Howe CL. Inflammatory cytokine-induced changes in neural network activity measured by waveform analysis of high-content calcium imaging in murine cortical neurons. Scientific Reports. 7: 9037. PMID 28831096 DOI: 10.1038/S41598-017-09182-5  0.307
2016 Wang Y, Cao Y, Mangalam AK, Guo Y, LaFrance-Corey RG, Gamez JD, Atanga PA, Clarkson BD, Zhang Y, Wang E, Angom RS, Dutta K, Ji B, Pirko I, Lucchinetti CF, ... Howe CL, et al. Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells. Journal of Cell Science. PMID 27591257 DOI: 10.1242/Jcs.190702  0.315
2016 Howe CL, LaFrance-Corey RG, Mirchia K, Sauer BM, McGovern RM, Reid JM, Buenz EJ. Neuroprotection mediated by inhibition of calpain during acute viral encephalitis. Scientific Reports. 6: 28699. PMID 27345730 DOI: 10.1038/Srep28699  0.339
2015 Walker-Caulfield ME, Guo Y, Johnson RK, McCarthy CB, Fitz-Gibbon PD, Lucchinetti CF, Howe CL. NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG. Journal of Neuroinflammation. 12: 185. PMID 26423139 DOI: 10.1186/S12974-015-0403-8  0.311
2013 Sauer BM, Schmalstieg WF, Howe CL. Axons are injured by antigen-specific CD8(+) T cells through a MHC class I- and granzyme B-dependent mechanism. Neurobiology of Disease. 59: 194-205. PMID 23899663 DOI: 10.1016/J.Nbd.2013.07.010  0.317
2012 Howe CL, Lafrance-Corey RG, Sundsbak RS, Sauer BM, Lafrance SJ, Buenz EJ, Schmalstieg WF. Hippocampal protection in mice with an attenuated inflammatory monocyte response to acute CNS picornavirus infection. Scientific Reports. 2: 545. PMID 22848791 DOI: 10.1038/Srep00545  0.325
2011 German CL, Sauer BM, Howe CL. The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures. Experimental Cell Research. 317: 1955-69. PMID 21619877 DOI: 10.1016/J.Yexcr.2011.05.009  0.328
2010 Arneson LN, Upshaw JL, Howe CL, Felts SJ, Rodriguez M, Pease LR, Colonna M. Retraction: TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 6557. PMID 20483797 DOI: 10.4049/Jimmunol.1090036  0.333
2009 Deb C, Lafrance-Corey RG, Zoecklein L, Papke L, Rodriguez M, Howe CL. Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 68: 1037-48. PMID 19680139 DOI: 10.1097/Nen.0B013E3181B5417E  0.311
2009 Buenz EJ, Sauer BM, Lafrance-Corey RG, Deb C, Denic A, German CL, Howe CL. Apoptosis of hippocampal pyramidal neurons is virus independent in a mouse model of acute neurovirulent picornavirus infection. The American Journal of Pathology. 175: 668-84. PMID 19608874 DOI: 10.2353/Ajpath.2009.081126  0.331
2009 Rodriguez M, Zoecklein L, Papke L, Gamez J, Denic A, Macura S, Howe C. Tumor necrosis factor α is reparative via TNFR1 in the hippocampus and via TNFR2 in the striatum after virus-induced encephalitis Brain Pathology. 19: 12-26. PMID 18422761 DOI: 10.1111/J.1750-3639.2008.00151.X  0.306
2008 Deb C, Howe CL. NKG2D contributes to efficient clearance of picornavirus from the acutely infected murine brain. Journal of Neurovirology. 14: 261-6. PMID 18569460 DOI: 10.1080/13550280802105002  0.314
2007 Howe CL, Ure D, Adelson JD, LaFrance-Corey R, Johnson A, Rodriguez M. CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination. Journal of Neuroimmunology. 188: 13-21. PMID 17493690 DOI: 10.1016/J.Jneuroim.2007.04.005  0.306
2007 Buenz EJ, Howe CL. Beta-methylamino-alanine (BMAA) injures hippocampal neurons in vivo. Neurotoxicology. 28: 702-4. PMID 17379313 DOI: 10.1016/J.Neuro.2007.02.010  0.318
2007 Howe CL, Adelson JD, Rodriguez M. Absence of perforin expression confers axonal protection despite demyelination. Neurobiology of Disease. 25: 354-9. PMID 17112732 DOI: 10.1016/J.Nbd.2006.10.001  0.309
2006 Rodriguez M, Zoecklein L, Gamez JD, Pavelko KD, Papke LM, Nakane S, Howe C, Radhakrishnan S, Hansen MJ, David CS, Warrington AE, Pease LR. STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 343-5. PMID 16352646 DOI: 10.1096/Fj.05-4650Fje  0.323
2005 Howe CL. Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk. Theoretical Biology & Medical Modelling. 2: 43. PMID 16236165 DOI: 10.1186/1742-4682-2-43  0.335
2005 Saxena S, Howe CL, Cosgaya JM, Steiner P, Hirling H, Chan JR, Weis J, Krüttgen A. Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking. Molecular and Cellular Neurosciences. 28: 571-87. PMID 15737746 DOI: 10.1016/J.Mcn.2004.11.011  0.368
2005 Howe CL, Mobley WC. Long-distance retrograde neurotrophic signaling. Current Opinion in Neurobiology. 15: 40-8. PMID 15721743 DOI: 10.1016/J.Conb.2005.01.010  0.571
2004 Saxena S, Howe CL, Cosgaya JM, Hu M, Weis J, Krüttgen A. Differences in the surface binding and endocytosis of neurotrophins by p75NTR. Molecular and Cellular Neurosciences. 26: 292-307. PMID 15207854 DOI: 10.1016/J.Mcn.2004.02.006  0.379
2004 Howe CL, Bieber AJ, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiology of Disease. 15: 120-31. PMID 14751777 DOI: 10.1016/J.Nbd.2003.09.002  0.337
2004 Howe CL, Mobley WC. Signaling endosome hypothesis: A cellular mechanism for long distance communication. Journal of Neurobiology. 58: 207-16. PMID 14704953 DOI: 10.1002/Neu.10323  0.536
2004 Delcroix JD, Valletta J, Wu C, Howe CL, Lai CF, Cooper JD, Belichenko PV, Salehi A, Mobley WC. Trafficking the NGF signal: implications for normal and degenerating neurons. Progress in Brain Research. 146: 3-23. PMID 14699953 DOI: 10.1016/S0079-6123(03)46001-9  0.659
2003 Rodriguez M, Zoecklein LJ, Howe CL, Pavelko KD, Gamez JD, Nakane S, Papke LM. Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection. Journal of Virology. 77: 12252-65. PMID 14581562 DOI: 10.1128/Jvi.77.22.12252-12265.2003  0.313
2003 Howe CL. Depolarization of PC12 cells induces neurite outgrowth and enhances nerve growth factor-induced neurite outgrowth in rats. Neuroscience Letters. 351: 41-5. PMID 14550909 DOI: 10.1016/S0304-3940(03)00915-7  0.36
2003 Howe CL. A Cbl:clathrin complex involved in NGF signaling for neurite outgrowth Neuroscience Research Communications. 33: 86-98. DOI: 10.1002/Nrc.10084  0.34
2001 Silver MA, Fagiolini M, Gillespie DC, Howe CL, Frank MG, Issa NP, Antonini A, Stryker MP. Infusion of nerve growth factor (NGF) into kitten visual cortex increases immunoreactivity for NGF, NGF receptors, and choline acetyltransferase in basal forebrain without affecting ocular dominance plasticity or column development. Neuroscience. 108: 569-85. PMID 11738495 DOI: 10.1016/S0306-4522(01)00391-8  0.371
2001 Howe CL, Valletta JS, Rusnak AS, Mobley WC. NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron. 32: 801-14. PMID 11738027 DOI: 10.1016/S0896-6273(01)00526-8  0.594
2001 Sofroniew MV, Howe CL, Mobley WC. Nerve growth factor signaling, neuroprotection, and neural repair. Annual Review of Neuroscience. 24: 1217-81. PMID 11520933 DOI: 10.1146/Annurev.Neuro.24.1.1217  0.579
2001 Cooper JD, Salehi A, Delcroix JD, Howe CL, Belichenko PV, Chua-Couzens J, Kilbridge JF, Carlson EJ, Epstein CJ, Mobley WC. Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proceedings of the National Academy of Sciences of the United States of America. 98: 10439-44. PMID 11504920 DOI: 10.1073/Pnas.181219298  0.626
2000 Beattie EC, Howe CL, Wilde A, Brodsky FM, Mobley WC. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7325-33. PMID 11007890 DOI: 10.1523/Jneurosci.20-19-07325.2000  0.567
1996 Beattie EC, Zhou J, Grimes ML, Bunnett NW, Howe CL, Mobley WC. A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration. Cold Spring Harbor Symposia On Quantitative Biology. 61: 389-406. PMID 9246468 DOI: 10.1101/Sqb.1996.061.01.042  0.56
1996 Yuen EC, Howe CL, Li Y, Holtzman DM, Mobley WC. Nerve growth factor and the neurotrophic factor hypothesis. Brain & Development. 18: 362-8. PMID 8891230 DOI: 10.1016/0387-7604(96)00051-4  0.611
1994 Rodriguez M, Prayoonwiwat N, Howe C, Sanborn K. Proteolipid protein gene expression in demyelination and remyelination of the central nervous system: A model for multiple sclerosis Journal of Neuropathology and Experimental Neurology. 53: 136-143. PMID 7509847 DOI: 10.1097/00005072-199403000-00004  0.306
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