Hai Yuan, Ph.D. - Publications
Affiliations: | 2006 | Northwestern University, Evanston, IL |
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical BiologyYear | Citation | Score | |||
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2010 | Mao J, Yuan H, Wang Y, Wan B, Pak D, He R, Franzblau SG. Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs. Bioorganic & Medicinal Chemistry Letters. 20: 1263-8. PMID 20022500 DOI: 10.1016/J.Bmcl.2009.11.105 | 0.349 | |||
2009 | Mao J, Yuan H, Wang Y, Wan B, Pieroni M, Huang Q, Van Breemen RB, Kozikowski AP, Franzblau SG. From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters Journal of Medicinal Chemistry. 52: 6966-6978. PMID 19863050 DOI: 10.1021/Jm900340A | 0.322 | |||
2007 | Yuan H, Silverman RB. Structural modifications of (1S,3S)-3-amino-4-difluoromethylenecyclopentanecarboxylic acid, a potent irreversible inhibitor of GABA aminotransferase. Bioorganic & Medicinal Chemistry Letters. 17: 1651-4. PMID 17267220 DOI: 10.1016/J.Bmcl.2006.12.119 | 0.513 | |||
2006 | Wang Z, Yuan H, Nikolic D, Van Breemen RB, Silverman RB. (+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway. Biochemistry. 45: 14513-22. PMID 17128990 DOI: 10.1021/Bi061592M | 0.531 | |||
2006 | Yuan H, Silverman RB. New substrates and inhibitors of gamma-aminobutyric acid aminotransferase containing bioisosteres of the carboxylic acid group: design, synthesis, and biological activity. Bioorganic & Medicinal Chemistry. 14: 1331-8. PMID 16263300 DOI: 10.1016/J.Bmc.2005.09.067 | 0.519 | |||
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