Hai Yuan, Ph.D. - Publications

Affiliations: 
2006 Northwestern University, Evanston, IL 
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology

5 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Mao J, Yuan H, Wang Y, Wan B, Pak D, He R, Franzblau SG. Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs. Bioorganic & Medicinal Chemistry Letters. 20: 1263-8. PMID 20022500 DOI: 10.1016/J.Bmcl.2009.11.105  0.349
2009 Mao J, Yuan H, Wang Y, Wan B, Pieroni M, Huang Q, Van Breemen RB, Kozikowski AP, Franzblau SG. From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters Journal of Medicinal Chemistry. 52: 6966-6978. PMID 19863050 DOI: 10.1021/Jm900340A  0.322
2007 Yuan H, Silverman RB. Structural modifications of (1S,3S)-3-amino-4-difluoromethylenecyclopentanecarboxylic acid, a potent irreversible inhibitor of GABA aminotransferase. Bioorganic & Medicinal Chemistry Letters. 17: 1651-4. PMID 17267220 DOI: 10.1016/J.Bmcl.2006.12.119  0.513
2006 Wang Z, Yuan H, Nikolic D, Van Breemen RB, Silverman RB. (+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway. Biochemistry. 45: 14513-22. PMID 17128990 DOI: 10.1021/Bi061592M  0.531
2006 Yuan H, Silverman RB. New substrates and inhibitors of gamma-aminobutyric acid aminotransferase containing bioisosteres of the carboxylic acid group: design, synthesis, and biological activity. Bioorganic & Medicinal Chemistry. 14: 1331-8. PMID 16263300 DOI: 10.1016/J.Bmc.2005.09.067  0.519
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