Year |
Citation |
Score |
2024 |
Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL. Lipoxin A yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling. Biorxiv : the Preprint Server For Biology. PMID 38370667 DOI: 10.1101/2024.02.06.579101 |
0.442 |
|
2023 |
Salvatore SR, Gómez-Cortés P, Rowart P, Woodcock SR, Angel de la Fuente M, Chang F, Schopfer FJ. Digestive interaction between dietary nitrite and dairy products generates novel nitrated linolenic acid products. Food Chemistry. 437: 137767. PMID 37879157 DOI: 10.1016/j.foodchem.2023.137767 |
0.472 |
|
2023 |
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, et al. Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies. Biorxiv : the Preprint Server For Biology. PMID 37645906 DOI: 10.1101/2023.08.11.552990 |
0.374 |
|
2023 |
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, et al. Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies. Redox Biology. 66: 102856. PMID 37633047 DOI: 10.1016/j.redox.2023.102856 |
0.374 |
|
2021 |
Fazzari M, Woodcock SR, Rowart P, Ricart K, Lancaster JR, Patel R, Vitturi DA, Freeman BA, Schopfer FJ. Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO) and nitroalkene (RNO) substituents. Redox Biology. 41: 101913. PMID 33819836 DOI: 10.1016/j.redox.2021.101913 |
0.521 |
|
2020 |
Fazzari M, Woodcock SR, Rowart P, Lancaster JJ, Vitturi DA, Freeman BA, Schopfer FJ. Corrigendum to “Endogenous formation of novel nitro-nitrate species as intermediates of fatty acid nitration” [Free Radic. Biol. Med. 145(1) (2019) S22] Free Radical Biology and Medicine. DOI: 10.1016/J.Freeradbiomed.2020.01.180 |
0.484 |
|
2018 |
Woodcock SR, Wendell SG, Schopfer FJ, Freeman BA. Synthesis of an Electrophilic Keto-Tetraene 15-oxo-Lipoxin A Methyl Ester a MIDA Boronate. Tetrahedron Letters. 59: 3524-3527. PMID 31379396 DOI: 10.1016/J.Tetlet.2018.08.014 |
0.401 |
|
2018 |
Fazzari M, Vitturi DA, Woodcock SR, Salvatore SR, Freeman BA, Schopfer FJ. Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids. Journal of Lipid Research. PMID 30545956 DOI: 10.1194/Jlr.M088815 |
0.52 |
|
2018 |
Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA. Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA- damaging agents on growth of triple-negative breast cells. The Journal of Biological Chemistry. PMID 30478172 DOI: 10.1074/Jbc.Ac118.005899 |
0.435 |
|
2018 |
Villacorta L, Minarrieta L, Salvatore SR, Khoo NK, Rom O, Gao Z, Berman RC, Jobbagy S, Li L, Woodcock SR, Chen YE, Freeman BA, Ferreira AM, Schopfer FJ, Vitturi DA. In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation. Redox Biology. 15: 522-531. PMID 29413964 DOI: 10.1016/J.Redox.2018.01.005 |
0.476 |
|
2018 |
Woodcock C, Woodcock S, Salvatore S, Davidson N, Huang Y, Freeman B. Electrophilic Nitro‐oleic Acid Inhibits Triple Negative Breast Cancer Cell Migration via Suppression of NF‐kB activity The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.934.1 |
0.373 |
|
2018 |
Skoko J, Asan A, Woodcock C, Cao J, Gaboriau D, Paulsen C, Attar M, Wingert B, Woodcock S, Schulte J, Ma H, Camacho C, Liu Y, Morrison C, Carroll K, et al. Loss of PRDX1 increases RAD51 Cys319 oxidation and decreases homologous recombination Free Radical Biology and Medicine. 128: S73-S74. DOI: 10.1016/J.Freeradbiomed.2018.10.159 |
0.332 |
|
2017 |
Woodcock CC, Huang Y, Woodcock SR, Salvatore SR, Singh B, Golin-Bisello F, Davidson NE, Neumann C, Freeman BA, Wendell SG. Nitro-fatty acid inhibition of triple negative breast cancer cell viability, migration, invasion and tumor growth. The Journal of Biological Chemistry. PMID 29158255 DOI: 10.1074/Jbc.M117.814368 |
0.399 |
|
2017 |
Verescakova H, Ambrozova G, Kubala L, Perecko T, Koudelka A, Vasicek O, Rudolph TK, Klinke A, Woodcock SR, Freeman BA, Pekarova M. Nitro-oleic acid regulates growth factor-induced differentiation of bone marrow-derived macrophages. Free Radical Biology & Medicine. PMID 28063941 DOI: 10.1016/J.Freeradbiomed.2017.01.003 |
0.388 |
|
2017 |
Skoko JJ, Asan A, Woodcock CC, Cao J, Gaboriau D, Paulsen CE, Attar M, Wingert BM, Woodcock SR, Schulte J, Ma H, Camacho CJ, Liu Y, Morrison CG, Carroll K, et al. Redox Regulation of RAD51 and Homologous Recombination by Peroxiredoxin 1 and Electrophilic Nitro-fatty Acids Free Radical Biology and Medicine. 112: 100-101. DOI: 10.1016/J.Freeradbiomed.2017.10.151 |
0.399 |
|
2017 |
Woodcock CS, Woodcock SR, Salvatore SR, Singh B, Golin-Bisello F, Davidson NE, Huang Y, Wendell SG, Freeman BA. Selective Inhibition of Triple Negative Breast Cancer Cell Mobility and Viability by Nitro-Oleic Acid Free Radical Biology and Medicine. 112: 99. DOI: 10.1016/J.Freeradbiomed.2017.10.148 |
0.426 |
|
2016 |
Turell L, Vitturi DA, Coitiño EL, Lebrato L, Moller MN, Sagasti C, Salvatore SR, Woodcock SR, Alvarez B, Schopfer FJ. The Chemical Basis of Thiol Addition to Nitro-Conjugated Linoleic Acid, a Protective Cell-Signaling Lipid. The Journal of Biological Chemistry. PMID 27923813 DOI: 10.1074/Jbc.M116.756288 |
0.51 |
|
2016 |
Fazzari M, Khoo NK, Woodcock SR, Jorkasky DK, Li L, Schopfer FJ, Freeman BA. Nitro-fatty acid pharmacokinetics in the adipose tissue compartment. Journal of Lipid Research. PMID 27913584 DOI: 10.1016/J.Freeradbiomed.2016.10.172 |
0.575 |
|
2016 |
Koudelka A, Ambrozova G, Klinke A, Fidlerova T, Martiskova H, Kuchta R, Rudolph TK, Kadlec J, Kuchtova Z, Woodcock SR, Freeman BA, Kubala L, Pekarova M. Nitro-Oleic Acid Prevents Hypoxia- and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction. Cardiovascular Drugs and Therapy. PMID 27858190 DOI: 10.1007/S10557-016-6700-3 |
0.389 |
|
2016 |
Ambrozova G, Fidlerova T, Martiskova H, Koudelka A, Rudolph TK, Woodcock SR, Freeman BA, Kubala L, Pekarova M. Nitro-Oleic Acid Inhibits Vascular Endothelial Inflammatory Responses and The Endothelial-Mesenchymal Transition. Biochimica Et Biophysica Acta. PMID 27431604 DOI: 10.1016/J.Bbagen.2016.07.010 |
0.439 |
|
2016 |
Vitturi DA, Minarrieta L, Salvatore SR, Khoo NK, Jobbagy S, Li L, Woodcock SR, Freeman BA, Villacorta L, Schopfer FJ. Inflammatory Generation and Pro-Resolving Signaling Actions of Conjugated Nitro-Linoleic Acid Free Radical Biology and Medicine. 100: S69. DOI: 10.1016/J.Freeradbiomed.2016.10.179 |
0.484 |
|
2015 |
Koenitzer JR, Bonacci G, Woodcock SR, Chen CS, Cantu-Medellin N, Kelley EE, Schopfer FJ. Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II. Redox Biology. 8: 1-10. PMID 26722838 DOI: 10.1016/J.Redox.2015.11.002 |
0.462 |
|
2015 |
Ambrozova G, Martiskova H, Koudelka A, Ravekes T, Rudolph TK, Klinke A, Rudolph V, Freeman BA, Woodcock SR, Kubala L, Pekarova M. Nitro-oleic acid modulates classical and regulatory activation of macrophages and their involvement in pro-fibrotic responses. Free Radical Biology & Medicine. PMID 26620549 DOI: 10.1016/J.Freeradbiomed.2015.11.026 |
0.44 |
|
2015 |
Rudolph TK, Ravekes T, Klinke A, Friedrichs K, Mollenhauer M, Pekarova M, Ambrozova G, Martiskova H, Kaur JJ, Matthes B, Schwoerer A, Woodcock SR, Kubala L, Freeman BA, Baldus S, et al. Nitrated fatty acids suppress angiotensin II mediated fibrotic remodeling and atrial fibrillation. Cardiovascular Research. PMID 26598510 DOI: 10.1093/Cvr/Cvv254 |
0.477 |
|
2015 |
Fazzari M, Khoo N, Woodcock SR, Li L, Freeman BA, Schopfer FJ. Generation and esterification of electrophilic fatty acid nitroalkenes in triacylglycerides. Free Radical Biology & Medicine. 87: 113-124. PMID 26066303 DOI: 10.1016/J.Freeradbiomed.2015.05.033 |
0.611 |
|
2015 |
Vitturi DA, Turell L, Lebrato L, Moller MN, Salvatore SR, Woodcock SR, Schopfer FJ, Alvarez B. Mechanism of Conjugated Nitrolinoleic Acid Addition to Biological Thiols: Insights from Kinetic and Mass Spectrometric Analysis Free Radical Biology and Medicine. 87: S125. DOI: 10.1016/J.Freeradbiomed.2015.10.327 |
0.457 |
|
2015 |
Vitturi DA, Minarrieta L, Villacorta L, Salvatore SR, Jobbagy S, Groomes P, Woodcock SR, Li L, Khoo NK, Freeman BA, Schopfer FJ. Regulation of Inflammatory Responses by Conjugated Linoleic Acid Nitration Free Radical Biology and Medicine. 87: S44-S45. DOI: 10.1016/J.Freeradbiomed.2015.10.118 |
0.486 |
|
2014 |
Klinke A, Möller A, Pekarova M, Ravekes T, Friedrichs K, Berlin M, Scheu KM, Kubala L, Kolarova H, Ambrozova G, Schermuly RT, Woodcock SR, Freeman BA, Rosenkranz S, Baldus S, et al. Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension American Journal of Respiratory Cell and Molecular Biology. 51: 155-162. PMID 24521348 DOI: 10.1165/Rcmb.2013-0063Oc |
0.394 |
|
2014 |
Woodcock SR, Salvatore SR, Bonacci G, Schopfer FJ, Freeman BA. Biomimetic nitration of conjugated linoleic acid: formation and characterization of naturally occurring conjugated nitrodienes. The Journal of Organic Chemistry. 79: 25-33. PMID 24350701 DOI: 10.1021/Jo4021562 |
0.554 |
|
2014 |
Artim DE, Bazely F, Daugherty SL, Sculptoreanu A, Koronowski KB, Schopfer FJ, Woodcock SR, Freeman BA, de Groat WC. Corrigendum to "Nitro-oleic acid targets transient receptor potential (TRP) channels in capsaicin sensitive afferent nerves of rat urinary bladder" [Exp. Neurol. 232 (2011) 90-99] Experimental Neurology. 261: 710. DOI: 10.1016/J.Expneurol.2014.08.008 |
0.326 |
|
2013 |
Vitturi DA, Chen CS, Woodcock SR, Salvatore SR, Bonacci G, Koenitzer JR, Stewart NA, Wakabayashi N, Kensler TW, Freeman BA, Schopfer FJ. Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. The Journal of Biological Chemistry. 288: 25626-37. PMID 23878198 DOI: 10.1074/Jbc.M113.486282 |
0.587 |
|
2013 |
Salvatore SR, Vitturi DA, Baker PR, Bonacci G, Koenitzer JR, Woodcock SR, Freeman BA, Schopfer FJ. Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine. Journal of Lipid Research. 54: 1998-2009. PMID 23620137 DOI: 10.1194/Jlr.M037804 |
0.613 |
|
2013 |
Woodcock SR, Bonacci G, Gelhaus SL, Schopfer FJ. Nitrated fatty acids: synthesis and measurement. Free Radical Biology & Medicine. 59: 14-26. PMID 23200809 DOI: 10.1016/J.Freeradbiomed.2012.11.015 |
0.573 |
|
2013 |
Fazzari M, Khoo N, Woodcock S, Golin- Bisello F, Schopfer FJ, Freeman BA. Metabolic Fate of Endogenous and Exogenously-Administered Electrophilic Fatty Acid Nitroalkenes: the Formation and Actions of Nitro-Fatty Acid-Containing Complex Lipids Free Radical Biology and Medicine. 65: S142. DOI: 10.1016/J.Freeradbiomed.2013.10.752 |
0.538 |
|
2013 |
Klinke A, Möller A, Ravekes T, Pekarova M, Friedrichs K, Schermuly RT, Kubala L, Kolarova H, Woodcock SR, Freeman BA, Baldus S, Rudolph V, Rudolph T. Protective Effects of Nitro-Fatty Acids in a Hypoxia-Induced Murine Model of Pulmonary Hypertension Free Radical Biology and Medicine. 65: S81. DOI: 10.1016/J.Freeradbiomed.2013.10.588 |
0.424 |
|
2012 |
Bonacci G, Baker PR, Salvatore SR, Shores D, Khoo NK, Koenitzer JR, Vitturi DA, Woodcock SR, Golin-Bisello F, Cole MP, Watkins S, St Croix C, Batthyany CI, Freeman BA, Schopfer FJ. Conjugated linoleic acid is a preferential substrate for fatty acid nitration. The Journal of Biological Chemistry. 287: 44071-82. PMID 23144452 DOI: 10.1074/Jbc.M112.401356 |
0.606 |
|
2011 |
Bonacci G, Asciutto EK, Woodcock SR, Salvatore SR, Freeman BA, Schopfer FJ. Gas-phase fragmentation analysis of nitro-fatty acids. Journal of the American Society For Mass Spectrometry. 22: 1534-51. PMID 21953257 DOI: 10.1007/S13361-011-0185-X |
0.477 |
|
2011 |
Artim DE, Bazely F, Daugherty SL, Sculptoreanu A, Koronowski KB, Schopfer FJ, Woodcock SR, Freeman BA, de Groat WC. Nitro-oleic acid targets transient receptor potential (TRP) channels in capsaicin sensitive afferent nerves of rat urinary bladder Experimental Neurology. 232: 90-99. PMID 21867704 DOI: 10.1016/J.Expneurol.2011.08.007 |
0.5 |
|
2011 |
Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Ylä-Herttuala S, Freeman BA, Levonen AL. Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. The Journal of Biological Chemistry. 286: 14019-27. PMID 21357422 DOI: 10.1074/Jbc.M110.190710 |
0.581 |
|
2010 |
Groeger AL, Cipollina C, Cole MP, Woodcock SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ. Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Nature Chemical Biology. 6: 433-41. PMID 20436486 DOI: 10.1038/Nchembio.367 |
0.587 |
|
2010 |
Sculptoreanu A, Kullmann FA, Artim DE, Bazley FA, Schopfer F, Woodcock S, Freeman BA, De Groat WC. Nitro-oleic acid inhibits firing and activates TRPV1- and TRPA1-mediated inward currents in dorsal root ganglion neurons from adult male rats Journal of Pharmacology and Experimental Therapeutics. 333: 883-895. PMID 20304940 DOI: 10.1124/Jpet.109.163154 |
0.368 |
|
2010 |
Rudolph TK, Rudolph V, Edreira MM, Cole MP, Bonacci G, Schopfer FJ, Woodcock SR, Franek A, Pekarova M, Khoo NK, Hasty AH, Baldus S, Freeman BA. Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 938-45. PMID 20167658 DOI: 10.1161/Atvbaha.109.201582 |
0.58 |
|
2010 |
Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, et al. Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions. The Journal of Biological Chemistry. 285: 12321-33. PMID 20097754 DOI: 10.1074/Jbc.M109.091512 |
0.458 |
|
2010 |
Khoo NK, Rudolph V, Cole MP, Golin-Bisello F, Schopfer FJ, Woodcock SR, Batthyany C, Freeman BA. Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids. Free Radical Biology & Medicine. 48: 230-9. PMID 19857569 DOI: 10.1016/J.Freeradbiomed.2009.10.046 |
0.453 |
|
2010 |
Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Woodcock SR, Cole MP, Baker PR, Ramani R, Freeman BA. Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion. Cardiovascular Research. 85: 155-66. PMID 19666678 DOI: 10.1093/Cvr/Cvp275 |
0.532 |
|
2009 |
Kansanen E, Jyrkkänen HK, Volger OL, Leinonen H, Kivelä AM, Häkkinen SK, Woodcock SR, Schopfer FJ, Horrevoets AJ, Ylä-Herttuala S, Freeman BA, Levonen AL. Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: Identification of heat shock response as the major pathway activated by nitro-oleic acid Journal of Biological Chemistry. 284: 33233-33241. PMID 19808663 DOI: 10.1074/Jbc.M109.064873 |
0.51 |
|
2009 |
Cole MP, Rudolph TK, Khoo NK, Motanya UN, Golin-Bisello F, Wertz JW, Schopfer FJ, Rudolph V, Woodcock SR, Bolisetty S, Ali MS, Zhang J, Chen YE, Agarwal A, Freeman BA, et al. Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury. Circulation Research. 105: 965-72. PMID 19797175 DOI: 10.1161/Circresaha.109.199075 |
0.555 |
|
2009 |
Rudolph V, Schopfer FJ, Khoo NKH, Rudolph TK, Cole MP, Woodcock SR, Bonacci G, Groeger AL, Golin-Bisello F, Chen CS, Baker PRS, Freeman BA. Nitro-fatty acid metabolome: saturation, desaturation, β-oxidation, and protein adduction Journal of Biological Chemistry. 284: 1461-1473. PMID 19015269 DOI: 10.1074/Jbc.M802298200 |
0.51 |
|
2008 |
Woodcock SR, Freeman BA. A new hammer in the redox toolbox: High-purity peroxynitrite for cell signaling and toxicology studies Chemical Research in Toxicology. 21: 2227-2228. PMID 19053325 DOI: 10.1021/Tx8004136 |
0.361 |
|
2008 |
Kelley EE, Batthyany CI, Hundley NJ, Woodcock SR, Bonacci G, Del Rio JM, Schopfer FJ, Lancaster JR, Freeman BA, Tarpey MM. Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase. The Journal of Biological Chemistry. 283: 36176-84. PMID 18974051 DOI: 10.1074/Jbc.M802402200 |
0.518 |
|
2008 |
Freeman BA, Baker PRS, Schopfer FJ, Woodcock SR, Napolitano A, D'Ischia M. Nitro-fatty acid formation and signaling Journal of Biological Chemistry. 283: 15515-15519. PMID 18285326 DOI: 10.1074/Jbc.R800004200 |
0.594 |
|
2007 |
Baker LM, Baker PR, Golin-Bisello F, Schopfer FJ, Fink M, Woodcock SR, Branchaud BP, Radi R, Freeman BA. Nitro-fatty acid reaction with glutathione and cysteine. Kinetic analysis of thiol alkylation by a Michael addition reaction. The Journal of Biological Chemistry. 282: 31085-93. PMID 17720974 DOI: 10.1074/Jbc.M704085200 |
0.698 |
|
2006 |
Woodcock SR, Marwitz AJ, Bruno P, Branchaud BP. Synthesis of nitrolipids. All four possible diastereomers of nitrooleic acids: (E)- and (Z)-, 9- and 10-nitro-octadec-9-enoic acids. Organic Letters. 8: 3931-4. PMID 16928041 DOI: 10.1021/Ol0613463 |
0.698 |
|
2005 |
Baker PR, Lin Y, Schopfer FJ, Woodcock SR, Groeger AL, Batthyany C, Sweeney S, Long MH, Iles KE, Baker LM, Branchaud BP, Chen YE, Freeman BA. Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands. The Journal of Biological Chemistry. 280: 42464-75. PMID 16227625 DOI: 10.1074/Jbc.M504212200 |
0.701 |
|
2005 |
Woodcock SR, Branchaud BP. Effect of ether versus ester tethering on Heck cyclizations Tetrahedron Letters. 46: 7213-7215. DOI: 10.1016/J.Tetlet.2005.08.072 |
0.589 |
|
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