| Year |
Citation |
Score |
| 2023 |
Domagalska MA, Barrett MP, Dujardin JC. Drug resistance in Leishmania: does it really matter? Trends in Parasitology. PMID 36803859 DOI: 10.1016/j.pt.2023.01.012 |
0.336 |
|
| 2022 |
Hefnawy A, Negreira G, Jara M, Cotton JA, Maes I, D'Haenens E, Imamura H, Cuypers B, Monsieurs P, Mouchtoglou C, De Winter H, Pintelon I, Timmermans JP, Berriman M, Sanders M, ... ... Dujardin JC, et al. Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel Antileishmanial Compound. Mbio. e0326421. PMID 35012338 DOI: 10.1128/mbio.03264-21 |
0.354 |
|
| 2021 |
Hammill JT, Sviripa VM, Kril LM, Ortiz D, Fargo CM, Kim HS, Chen Y, Rector J, Rice AL, Domagalska MA, Begley KL, Liu C, Rangnekar VM, Dujardin JC, Watt DS, et al. Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents. Journal of Medicinal Chemistry. PMID 34355566 DOI: 10.1021/acs.jmedchem.1c00813 |
0.311 |
|
| 2019 |
Domagalska MA, Imamura H, Sanders M, Van den Broeck F, Bhattarai NR, Vanaerschot M, Maes I, D'Haenens E, Rai K, Rijal S, Berriman M, Cotton JA, Dujardin JC. Genomes of Leishmania parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent. Plos Neglected Tropical Diseases. 13: e0007900. PMID 31830038 DOI: 10.1371/Journal.Pntd.0007900 |
0.342 |
|
| 2019 |
Seblova V, Dujardin JC, Rijal S, Domagalska MA, Volf P. ISC1, a new Leishmania donovani population emerging in the Indian sub-continent: Vector competence of Phlebotomus argentipes. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 76: 104073. PMID 31629887 DOI: 10.1016/J.Meegid.2019.104073 |
0.413 |
|
| 2019 |
Patino LH, Imamura H, Cruz-Saavedra L, Pavia P, Muskus C, Méndez C, Dujardin JC, Ramírez JD. Major changes in chromosomal somy, gene expression and gene dosage driven by Sb in Leishmania braziliensis and Leishmania panamensis. Scientific Reports. 9: 9485. PMID 31263131 DOI: 10.1038/s41598-019-45538-9 |
0.361 |
|
| 2018 |
Urrea DA, Duitama J, Imamura H, Álzate JF, Gil J, Muñoz N, Villa JA, Dujardin JC, Ramirez-Pineda JR, Triana-Chavez O. Genomic Analysis of Colombian Leishmania panamensis strains with different level of virulence. Scientific Reports. 8: 17336. PMID 30478412 DOI: 10.1038/S41598-018-35778-6 |
0.38 |
|
| 2018 |
Bussotti G, Gouzelou E, Côrtes Boité M, Kherachi I, Harrat Z, Eddaikra N, Mottram JC, Antoniou M, Christodoulou V, Bali A, Guerfali FZ, Laouini D, Mukhtar M, Dumetz F, Dujardin JC, et al. Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification. Mbio. 9. PMID 30401775 DOI: 10.1128/Mbio.01399-18 |
0.383 |
|
| 2018 |
Hefnawy A, Cantizani J, Peña I, Manzano P, Rijal S, Dujardin JC, De Muylder G, Martin J. Importance of secondary screening with clinical isolates for anti-leishmania drug discovery. Scientific Reports. 8: 11765. PMID 30082744 DOI: 10.1038/S41598-018-30040-5 |
0.405 |
|
| 2018 |
Cuypers B, Berg M, Imamura H, Dumetz F, De Muylder G, Domagalska MA, Rijal S, Bhattarai NR, Maes I, Sanders M, Cotton JA, Meysman P, Laukens K, Dujardin JC. Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 29679745 DOI: 10.1016/J.Meegid.2018.04.021 |
0.347 |
|
| 2017 |
Ponte-Sucre A, Gamarro F, Dujardin JC, Barrett MP, López-Vélez R, García-Hernández R, Pountain AW, Mwenechanya R, Papadopoulou B. Drug resistance and treatment failure in leishmaniasis: A 21st century challenge. Plos Neglected Tropical Diseases. 11: e0006052. PMID 29240765 DOI: 10.1371/Journal.Pntd.0006052 |
0.305 |
|
| 2017 |
Prieto Barja P, Pescher P, Bussotti G, Dumetz F, Imamura H, Kedra D, Domagalska M, Chaumeau V, Himmelbauer H, Pages M, Sterkers Y, Dujardin JC, Notredame C, Späth GF. Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani. Nature Ecology & Evolution. PMID 29109466 DOI: 10.1038/S41559-017-0361-X |
0.35 |
|
| 2017 |
Verma A, Bhandari V, Deep DK, Sundar S, Dujardin JC, Singh R, Salotra P. Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani. International Journal For Parasitology. Drugs and Drug Resistance. 7: 370-377. PMID 29035735 DOI: 10.1016/j.ijpddr.2017.10.004 |
0.327 |
|
| 2017 |
Tihon E, Imamura H, Van den Broeck F, Vermeiren L, Dujardin JC, Van Den Abbeele J. Genomic analysis of Isometamidium Chloride resistance in Trypanosoma congolense. International Journal For Parasitology. Drugs and Drug Resistance. 7: 350-361. PMID 29032180 DOI: 10.1016/J.Ijpddr.2017.10.002 |
0.455 |
|
| 2017 |
Tihon E, Imamura H, Dujardin JC, Van Den Abbeele J. Evidence for viable and stable triploid Trypanosoma congolense parasites. Parasites & Vectors. 10: 468. PMID 29017575 DOI: 10.1186/S13071-017-2406-Z |
0.336 |
|
| 2017 |
Tihon E, Imamura H, Dujardin JC, Van Den Abbeele J, Van den Broeck F. Discovery and genomic analyses of hybridization between divergent lineages of Trypanosoma congolense, causative agent of Animal African Trypanosomiasis. Molecular Ecology. PMID 28752916 DOI: 10.1111/Mec.14271 |
0.397 |
|
| 2017 |
Jara M, Berg M, Caljon G, de Muylder G, Cuypers B, Castillo D, Maes I, Orozco MDC, Vanaerschot M, Dujardin JC, Arevalo J. Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage. Plos One. 12: e0180532. PMID 28742826 DOI: 10.1371/Journal.Pone.0180532 |
0.332 |
|
| 2017 |
Deep DK, Singh R, Bhandari V, Verma A, Sharma V, Wajid S, Sundar S, Ramesh V, Dujardin JC, Salotra P. Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress. Plos Neglected Tropical Diseases. 11: e0005641. PMID 28575060 DOI: 10.1371/journal.pntd.0005641 |
0.321 |
|
| 2017 |
Chowdhury SR, Kumar A, Godinho JLP, De Macedo Silva ST, Zuma AA, Saha S, Kumari N, Rodrigues JCF, Sundar S, Dujardin JC, Roy S, De Souza W, Mukhopadhyay S, Majumder HK. Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB. Biochemical Pharmacology. PMID 28483460 DOI: 10.1016/J.Bcp.2017.05.002 |
0.443 |
|
| 2017 |
Rai K, Bhattarai NR, Vanaerschot M, Imamura H, Gebru G, Khanal B, Rijal S, Boelaert M, Pal C, Karki P, Dujardin JC, Van der Auwera G. Single locus genotyping to track Leishmania donovani in the Indian subcontinent: Application in Nepal. Plos Neglected Tropical Diseases. 11: e0005420. PMID 28249021 DOI: 10.1371/Journal.Pntd.0005420 |
0.336 |
|
| 2016 |
De Muylder G, Vanhollebeke B, Caljon G, Wolfe AR, McKerrow J, Dujardin JC. Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions. Plos Neglected Tropical Diseases. 10: e0005234. PMID 28036391 DOI: 10.1371/Journal.Pntd.0005234 |
0.368 |
|
| 2016 |
Hefnawy A, Berg M, Dujardin JC, De Muylder G. Exploiting Knowledge on Leishmania Drug Resistance to Support the Quest for New Drugs. Trends in Parasitology. PMID 27993477 DOI: 10.1016/J.Pt.2016.11.003 |
0.405 |
|
| 2016 |
Van der Auwera G, Bart A, Chicharro C, Cortes S, Davidsson L, Di Muccio T, Dujardin JC, Felger I, Paglia MG, Grimm F, Harms G, Jaffe CL, Manser M, Ravel C, Robert-Gangneux F, et al. Comparison of Leishmania typing results obtained from 16 European clinical laboratories in 2014. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin. 21. PMID 27983510 DOI: 10.2807/1560-7917.Es.2016.21.49.30418 |
0.341 |
|
| 2016 |
Caljon G, De Muylder G, Durnez L, Jennes W, Vanaerschot M, Dujardin JC. Alice in microbes' land: adaptations and counter-adaptations of vector-borne parasitic protozoa and their hosts. Fems Microbiology Reviews. PMID 27400870 DOI: 10.1093/Femsre/Fuw018 |
0.324 |
|
| 2016 |
Drini S, Criscuolo A, Lechat P, Imamura H, Skalický T, Rachidi N, Lukeš J, Dujardin JC, Späth GF. Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids. Genome Biology and Evolution. 8: 1980-1995. PMID 27371955 DOI: 10.1093/Gbe/Evw140 |
0.319 |
|
| 2016 |
Mondelaers A, Sanchez-Cañete MP, Hendrickx S, Eberhardt E, Garcia-Hernandez R, Lachaud L, Cotton J, Sanders M, Cuypers B, Imamura H, Dujardin JC, Delputte P, Cos P, Caljon G, Gamarro F, et al. Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intracellular Amastigotes. Plos One. 11: e0154101. PMID 27123924 DOI: 10.1371/Journal.Pone.0154101 |
0.45 |
|
| 2016 |
Cuypers B, Lecordier L, Meehan CJ, Van den Broeck F, Imamura H, Büscher P, Dujardin JC, Laukens K, Schnaufer A, Dewar C, Lewis M, Balmer O, Azurago T, Kyei-Faried S, Ohene SA, et al. Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection. Mbio. 7. PMID 27073096 DOI: 10.1128/Mbio.02198-15 |
0.36 |
|
| 2016 |
Kauffmann F, Dumetz F, Hendrickx S, Muraille E, Dujardin JC, Maes L, Magez S, De Trez C. In vivo characterization of two additional Leishmania donovani strains using the murine and hamster model. Parasite Immunology. PMID 27012562 DOI: 10.1111/Pim.12316 |
0.315 |
|
| 2016 |
Imamura H, Downing T, Van den Broeck F, Sanders MJ, Rijal S, Sundar S, Mannaert A, Vanaerschot M, Berg M, De Muylder G, Dumetz F, Cuypers B, Maes I, Domagalska M, Decuypere S, ... ... Dujardin JC, et al. Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent. Elife. 5. PMID 27003289 DOI: 10.7554/Elife.12613 |
0.748 |
|
| 2016 |
Shaw CD, Lonchamp J, Downing T, Imamura H, Freeman TM, Cotton JA, Sanders M, Blackburn G, Dujardin JC, Rijal S, Khanal B, Illingworth CJ, Coombs GH, Carter KC. In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization. Molecular Microbiology. 99: 1134-48. PMID 26713880 DOI: 10.1111/Mmi.13291 |
0.41 |
|
| 2015 |
Hendrickx S, Leemans A, Mondelaers A, Rijal S, Khanal B, Dujardin JC, Delputte P, Cos P, Maes L. Comparative Fitness of a Parent Leishmania donovani Clinical Isolate and Its Experimentally Derived Paromomycin-Resistant Strain. Plos One. 10: e0140139. PMID 26469696 DOI: 10.1371/Journal.Pone.0140139 |
0.478 |
|
| 2015 |
Ostyn B, Uranw S, Bhattarai NR, Das ML, Rai K, Tersago K, Pokhrel Y, Durnez L, Marasini B, Van der Auwera G, Dujardin JC, Coosemans M, Argaw D, Boelaert M, Rijal S. Transmission of Leishmania donovani in the Hills of Eastern Nepal, an Outbreak Investigation in Okhaldhunga and Bhojpur Districts. Plos Neglected Tropical Diseases. 9: e0003966. PMID 26252494 DOI: 10.1371/Journal.Pntd.0003966 |
0.325 |
|
| 2015 |
Suárez M, Valencia BM, Jara M, Alba M, Boggild AK, Dujardin JC, Llanos-Cuentas A, Arevalo J, Adaui V. Quantification of Leishmania (Viannia) Kinetoplast DNA in Ulcers of Cutaneous Leishmaniasis Reveals Inter-site and Inter-sampling Variability in Parasite Load. Plos Neglected Tropical Diseases. 9: e0003936. PMID 26204525 DOI: 10.1371/Journal.Pntd.0003936 |
0.322 |
|
| 2015 |
Van der Auwera G, Dujardin JC. Species typing in dermal leishmaniasis. Clinical Microbiology Reviews. 28: 265-94. PMID 25672782 DOI: 10.1128/Cmr.00104-14 |
0.313 |
|
| 2015 |
Berg M, García-Hernández R, Cuypers B, Vanaerschot M, Manzano JI, Poveda JA, Ferragut JA, Castanys S, Dujardin JC, Gamarro F. Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations. Antimicrobial Agents and Chemotherapy. 59: 2242-55. PMID 25645828 DOI: 10.1128/Aac.04231-14 |
0.423 |
|
| 2014 |
Dujardin JC, Mannaert A, Durrant C, Cotton JA. Mosaic aneuploidy in Leishmania: the perspective of whole genome sequencing. Trends in Parasitology. 30: 554-5. PMID 25458156 DOI: 10.1016/J.Pt.2014.09.004 |
0.3 |
|
| 2014 |
Montalvo AM, Fraga J, El Safi S, Gramiccia M, Jaffe CL, Dujardin JC, Van der Auwera G. Direct Leishmania species typing in Old World clinical samples: evaluation of 3 sensitive methods based on the heat-shock protein 70 gene. Diagnostic Microbiology and Infectious Disease. 80: 35-9. PMID 25038029 DOI: 10.1016/J.Diagmicrobio.2014.05.012 |
0.322 |
|
| 2014 |
Ostyn B, Hasker E, Dorlo TP, Rijal S, Sundar S, Dujardin JC, Boelaert M. Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia. Plos One. 9: e100220. PMID 24941345 DOI: 10.1371/Journal.Pone.0100220 |
0.332 |
|
| 2014 |
Vanaerschot M, Dumetz F, Roy S, Ponte-Sucre A, Arevalo J, Dujardin JC. Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype? Expert Review of Anti-Infective Therapy. 12: 937-46. PMID 24802998 DOI: 10.1586/14787210.2014.916614 |
0.349 |
|
| 2014 |
Nühs A, Schäfer C, Zander D, Trübe L, Tejera Nevado P, Schmidt S, Arevalo J, Adaui V, Maes L, Dujardin JC, Clos J. A novel marker, ARM58, confers antimony resistance to Leishmania spp. International Journal For Parasitology. Drugs and Drug Resistance. 4: 37-47. PMID 24596667 DOI: 10.1016/J.Ijpddr.2013.11.004 |
0.449 |
|
| 2014 |
Bhandari V, Sundar S, Dujardin JC, Salotra P. Elucidation of cellular mechanisms involved in experimental paromomycin resistance in Leishmania donovani. Antimicrobial Agents and Chemotherapy. 58: 2580-5. PMID 24550335 DOI: 10.1128/AAC.01574-13 |
0.356 |
|
| 2014 |
Fraga J, Fernandez-Calienes A, Montalvo AM, Maes I, Dujardin JC, Van der Auwera G. Differentiation between Trypanosoma cruzi and Trypanosoma rangeli using heat-shock protein 70 polymorphisms. Tropical Medicine & International Health : Tm & Ih. 19: 195-206. PMID 24224809 DOI: 10.1111/Tmi.12222 |
0.35 |
|
| 2014 |
van den Bogaart E, Schoone GJ, England P, Faber D, Orrling KM, Dujardin JC, Sundar S, Schallig HD, Adams ER. Simple colorimetric trypanothione reductase-based assay for high-throughput screening of drugs against Leishmania intracellular amastigotes. Antimicrobial Agents and Chemotherapy. 58: 527-35. PMID 24189262 DOI: 10.1128/Aac.00751-13 |
0.352 |
|
| 2014 |
Vanaerschot M, Huijben S, Van den Broeck F, Dujardin JC. Drug resistance in vectorborne parasites: multiple actors and scenarios for an evolutionary arms race. Fems Microbiology Reviews. 38: 41-55. PMID 23815683 DOI: 10.1111/1574-6976.12032 |
0.453 |
|
| 2014 |
Breitling R, Bakker BM, Barrett MP, Decuypere S, Dujardin JC. Metabolomic systems biology of protozoan parasites Genetics Meets Metabolomics: From Experiment to Systems Biology. 73-84. DOI: 10.1007/978-1-4614-1689-0_6 |
0.684 |
|
| 2013 |
Rai K, Cuypers B, Bhattarai NR, Uranw S, Berg M, Ostyn B, Dujardin JC, Rijal S, Vanaerschot M. Relapse after treatment with miltefosine for visceral leishmaniasis is associated with increased infectivity of the infecting Leishmania donovani strain. Mbio. 4: e00611-13. PMID 24105765 DOI: 10.1128/Mbio.00611-13 |
0.456 |
|
| 2013 |
Berg M, Vanaerschot M, Jankevics A, Cuypers B, Maes I, Mukherjee S, Khanal B, Rijal S, Roy S, Opperdoes F, Breitling R, Dujardin JC. Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure. Molecular Microbiology. 90: 428-42. PMID 24020363 DOI: 10.1111/mmi.12374 |
0.332 |
|
| 2013 |
Jara M, Adaui V, Valencia BM, Martinez D, Alba M, Castrillon C, Cruz M, Cruz I, Van der Auwera G, Llanos-Cuentas A, Dujardin JC, Arevalo J. Real-time PCR assay for detection and quantification of Leishmania (Viannia) organisms in skin and mucosal lesions: exploratory study of parasite load and clinical parameters. Journal of Clinical Microbiology. 51: 1826-33. PMID 23554201 DOI: 10.1128/Jcm.00208-13 |
0.322 |
|
| 2013 |
Berg M, Mannaert A, Vanaerschot M, Van Der Auwera G, Dujardin JC. (Post-) Genomic approaches to tackle drug resistance in Leishmania. Parasitology. 140: 1492-505. PMID 23480865 DOI: 10.1017/S0031182013000140 |
0.446 |
|
| 2013 |
Rijal S, Ostyn B, Uranw S, Rai K, Bhattarai NR, Dorlo TP, Beijnen JH, Vanaerschot M, Decuypere S, Dhakal SS, Das ML, Karki P, Singh R, Boelaert M, Dujardin JC. Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 56: 1530-8. PMID 23425958 DOI: 10.1093/Cid/Cit102 |
0.735 |
|
| 2013 |
Mukherjee B, Mukhopadhyay R, Bannerjee B, Chowdhury S, Mukherjee S, Naskar K, Allam US, Chakravortty D, Sundar S, Dujardin JC, Roy S. Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1. Proceedings of the National Academy of Sciences of the United States of America. 110: E575-82. PMID 23341611 DOI: 10.1073/Pnas.1213839110 |
0.3 |
|
| 2013 |
Vanaerschot M, Decuypere S, Berg M, Roy S, Dujardin JC. Drug-resistant microorganisms with a higher fitness--can medicines boost pathogens? Critical Reviews in Microbiology. 39: 384-94. PMID 22950457 DOI: 10.3109/1040841X.2012.716818 |
0.727 |
|
| 2013 |
Dujardin JC, Decuypere S. Epidemiology of leishmaniasis in the time of drug resistance Drug Resistance in Leishmania Parasites: Consequences, Molecular Mechanisms and Possible Treatments. 65-84. DOI: 10.1007/978-3-7091-1125-3_4 |
0.731 |
|
| 2012 |
Stauch A, Duerr HP, Dujardin JC, Vanaerschot M, Sundar S, Eichner M. Treatment of visceral leishmaniasis: model-based analyses on the spread of antimony-resistant L. donovani in Bihar, India. Plos Neglected Tropical Diseases. 6: e1973. PMID 23285309 DOI: 10.1371/Journal.Pntd.0001973 |
0.434 |
|
| 2012 |
Odiwuor S, Muia A, Magiri C, Maes I, Kirigi G, Dujardin JC, Wasunna M, Mbuchi M, Auwera GV. Identification of Leishmania tropica from micro-foci of cutaneous leishmaniasis in the Kenyan Rift Valley. Pathogens and Global Health. 106: 159-65. PMID 23265373 DOI: 10.1179/2047773212Y.0000000015 |
0.323 |
|
| 2012 |
Fraga J, Veland N, Montalvo AM, Praet N, Boggild AK, Valencia BM, Arévalo J, Llanos-Cuentas A, Dujardin JC, Van der Auwera G. Accurate and rapid species typing from cutaneous and mucocutaneous leishmaniasis lesions of the New World. Diagnostic Microbiology and Infectious Disease. 74: 142-50. PMID 22819605 DOI: 10.1016/J.Diagmicrobio.2012.06.010 |
0.323 |
|
| 2012 |
Mannaert A, Downing T, Imamura H, Dujardin JC. Adaptive mechanisms in pathogens: universal aneuploidy in Leishmania. Trends in Parasitology. 28: 370-6. PMID 22789456 DOI: 10.1016/J.Pt.2012.06.003 |
0.303 |
|
| 2012 |
Vanaerschot M, Decuypere S, Downing T, Imamura H, Stark O, De Doncker S, Roy S, Ostyn B, Maes L, Khanal B, Boelaert M, Schönian G, Berriman M, Chappuis F, Dujardin JC, et al. Genetic markers for SSG resistance in Leishmania donovani and SSG treatment failure in visceral leishmaniasis patients of the Indian subcontinent. The Journal of Infectious Diseases. 206: 752-5. PMID 22753945 DOI: 10.1093/Infdis/Jis424 |
0.754 |
|
| 2012 |
Hendrickx S, Inocêncio da Luz RA, Bhandari V, Kuypers K, Shaw CD, Lonchamp J, Salotra P, Carter K, Sundar S, Rijal S, Dujardin JC, Cos P, Maes L. Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol. Plos Neglected Tropical Diseases. 6: e1664. PMID 22666513 DOI: 10.1371/Journal.Pntd.0001664 |
0.318 |
|
| 2012 |
Odiwuor S, Veland N, Maes I, Arévalo J, Dujardin JC, Van der Auwera G. Evolution of the Leishmania braziliensis species complex from amplified fragment length polymorphisms, and clinical implications. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 12: 1994-2002. PMID 22516226 DOI: 10.1016/J.Meegid.2012.03.028 |
0.363 |
|
| 2012 |
Decuypere S, Vanaerschot M, Brunker K, Imamura H, Müller S, Khanal B, Rijal S, Dujardin JC, Coombs GH. Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background. Plos Neglected Tropical Diseases. 6: e1514. PMID 22389733 DOI: 10.1371/Journal.Pntd.0001514 |
0.749 |
|
| 2012 |
Downing T, Stark O, Vanaerschot M, Imamura H, Sanders M, Decuypere S, de Doncker S, Maes I, Rijal S, Sundar S, Dujardin JC, Berriman M, Schönian G. Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 12: 149-59. PMID 22119748 DOI: 10.1016/J.Meegid.2011.11.005 |
0.736 |
|
| 2012 |
Imamura H, Mannaert A, Downing T, Berriman M, Dujardin J. In the Shadow of the Genome: A Challenging Journey to Diversity in Leishmania donovani Embnet.Journal. 17: 37. DOI: 10.14806/Ej.17.B.271 |
0.447 |
|
| 2011 |
Downing T, Imamura H, Decuypere S, Clark TG, Coombs GH, Cotton JA, Hilley JD, de Doncker S, Maes I, Mottram JC, Quail MA, Rijal S, Sanders M, Schönian G, Stark O, ... ... Dujardin JC, et al. Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance. Genome Research. 21: 2143-56. PMID 22038251 DOI: 10.1101/Gr.123430.111 |
0.744 |
|
| 2011 |
Mukhopadhyay R, Mukherjee S, Mukherjee B, Naskar K, Mondal D, Decuypere S, Ostyn B, Prajapati VK, Sundar S, Dujardin JC, Roy S. Characterisation of antimony-resistant Leishmania donovani isolates: biochemical and biophysical studies and interaction with host cells. International Journal For Parasitology. 41: 1311-21. PMID 21920365 DOI: 10.1016/J.Ijpara.2011.07.013 |
0.721 |
|
| 2011 |
Adaui V, Maes I, Huyse T, Van den Broeck F, Talledo M, Kuhls K, De Doncker S, Maes L, Llanos-Cuentas A, Schönian G, Arevalo J, Dujardin JC. Multilocus genotyping reveals a polyphyletic pattern among naturally antimony-resistant Leishmania braziliensis isolates from Peru. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 11: 1873-80. PMID 21871584 DOI: 10.1016/J.Meegid.2011.08.008 |
0.45 |
|
| 2011 |
Vanaerschot M, De Doncker S, Rijal S, Maes L, Dujardin JC, Decuypere S. Antimonial resistance in Leishmania donovani is associated with increased in vivo parasite burden. Plos One. 6: e23120. PMID 21829701 DOI: 10.1371/Journal.Pone.0023120 |
0.735 |
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| 2011 |
Ouakad M, Vanaerschot M, Rijal S, Sundar S, Speybroeck N, Kestens L, Boel L, De Doncker S, Maes I, Decuypere S, Dujardin JC. Increased metacyclogenesis of antimony-resistant Leishmania donovani clinical lines. Parasitology. 138: 1392-9. PMID 21819638 DOI: 10.1017/S0031182011001120 |
0.741 |
|
| 2011 |
Adaui V, Castillo D, Zimic M, Gutierrez A, Decuypere S, Vanaerschot M, De Doncker S, Schnorbusch K, Maes I, Van der Auwera G, Maes L, Llanos-Cuentas A, Arevalo J, Dujardin JC. Comparative gene expression analysis throughout the life cycle of Leishmania braziliensis: diversity of expression profiles among clinical isolates. Plos Neglected Tropical Diseases. 5: e1021. PMID 21572980 DOI: 10.1371/Journal.Pntd.0001021 |
0.692 |
|
| 2011 |
Odiwuor S, De Doncker S, Maes I, Dujardin JC, Van der Auwera G. Natural Leishmania donovani/Leishmania aethiopica hybrids identified from Ethiopia. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 11: 2113-8. PMID 21558020 DOI: 10.1016/J.Meegid.2011.04.026 |
0.321 |
|
| 2011 |
Odiwuor S, Vuylsteke M, De Doncker S, Maes I, Mbuchi M, Dujardin JC, Van der Auwera G. Leishmania AFLP: paving the way towards improved molecular assays and markers of diversity. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 11: 960-7. PMID 21439405 DOI: 10.1016/J.Meegid.2011.03.008 |
0.407 |
|
| 2011 |
Adaui V, Schnorbusch K, Zimic M, Gutiérrez A, Decuypere S, Vanaerschot M, DE Doncker S, Maes I, Llanos-Cuentas A, Chappuis F, Arévalo J, Dujardin JC. Comparison of gene expression patterns among Leishmania braziliensis clinical isolates showing a different in vitro susceptibility to pentavalent antimony. Parasitology. 138: 183-93. PMID 20678296 DOI: 10.1017/S0031182010001095 |
0.726 |
|
| 2011 |
t'Kindt R, Jankevics A, Scheltema RA, Zheng L, Watson DG, Dujardin J, Breitling R, Coombs GH, Decuypere S. Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis (vol 398, pg 2059, 2010) Analytical and Bioanalytical Chemistry. 400: 635-635. DOI: 10.1007/S00216-011-4796-7 |
0.301 |
|
| 2010 |
t'Kindt R, Scheltema RA, Jankevics A, Brunker K, Rijal S, Dujardin JC, Breitling R, Watson DG, Coombs GH, Decuypere S. Metabolomics to unveil and understand phenotypic diversity between pathogen populations. Plos Neglected Tropical Diseases. 4: e904. PMID 21152055 DOI: 10.1371/Journal.Pntd.0000904 |
0.751 |
|
| 2010 |
t'Kindt R, Jankevics A, Scheltema RA, Zheng L, Watson DG, Dujardin JC, Breitling R, Coombs GH, Decuypere S. Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis. Analytical and Bioanalytical Chemistry. 398: 2059-69. PMID 20824428 DOI: 10.1007/s00216-010-4139-0 |
0.673 |
|
| 2010 |
Vanaerschot M, Maes I, Ouakad M, Adaui V, Maes L, De Doncker S, Rijal S, Chappuis F, Dujardin JC, Decuypere S. Linking in vitro and in vivo survival of clinical Leishmania donovani strains. Plos One. 5: e12211. PMID 20808916 DOI: 10.1371/Journal.Pone.0012211 |
0.723 |
|
| 2010 |
Dujardin JC, González-Pacanowska D, Croft SL, Olesen OF, Späth GF. Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas. Trends in Parasitology. 26: 395-403. PMID 20538522 DOI: 10.1016/J.Pt.2010.04.012 |
0.34 |
|
| 2010 |
Torres DC, Adaui V, Ribeiro-Alves M, Romero GA, Arévalo J, Cupolillo E, Dujardin JC. Targeted gene expression profiling in Leishmania braziliensis and Leishmania guyanensis parasites isolated from Brazilian patients with different antimonial treatment outcomes. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 10: 727-33. PMID 20478409 DOI: 10.1016/J.Meegid.2010.05.006 |
0.423 |
|
| 2010 |
Montalvo Alvarez AM, Nodarse JF, Goodridge IM, Fidalgo LM, Marin M, Van Der Auwera G, Dujardin JC, Bernal ID, Muskus C. Differentiation of Leishmania (Viannia) panamensis and Leishmania (V.) guyanensis using BccI for hsp70 PCR-RFLP. Transactions of the Royal Society of Tropical Medicine and Hygiene. 104: 364-7. PMID 20227738 DOI: 10.1016/J.Trstmh.2009.12.002 |
0.363 |
|
| 2010 |
Scheltema RA, Decuypere S, T'kindt R, Dujardin JC, Coombs GH, Breitling R. The potential of metabolomics for Leishmania research in the post-genomics era. Parasitology. 137: 1291-302. PMID 20109253 DOI: 10.1017/S0031182009992022 |
0.697 |
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| 2009 |
da Luz RI, Vermeersch M, Dujardin JC, Cos P, Maes L. In vitro sensitivity testing of Leishmania clinical field isolates: preconditioning of promastigotes enhances infectivity for macrophage host cells. Antimicrobial Agents and Chemotherapy. 53: 5197-203. PMID 19752271 DOI: 10.1128/Aac.00866-09 |
0.414 |
|
| 2009 |
Bhattarai NR, Das ML, Rijal S, van der Auwera G, Picado A, Khanal B, Roy L, Speybroeck N, Berkvens D, Davies CR, Coosemans M, Boelaert M, Dujardin JC. Natural infection of Phlebotomus argentipes with Leishmania and other trypanosomatids in a visceral leishmaniasis endemic region of Nepal. Transactions of the Royal Society of Tropical Medicine and Hygiene. 103: 1087-92. PMID 19345387 DOI: 10.1016/J.Trstmh.2009.03.008 |
0.314 |
|
| 2009 |
Maurer-Cecchini A, Decuypere S, Chappuis F, Alexandrenne C, De Doncker S, Boelaert M, Dujardin JC, Loutan L, Dayer JM, Tulliano G, Arevalo J, Llanos-Cuentas A, Chizzolini C. Immunological determinants of clinical outcome in Peruvian patients with tegumentary leishmaniasis treated with pentavalent antimonials. Infection and Immunity. 77: 2022-9. PMID 19237520 DOI: 10.1128/Iai.01513-08 |
0.675 |
|
| 2009 |
Dujardin JC. Structure, dynamics and function of Leishmania genome: resolving the puzzle of infection, genetics and evolution? Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 9: 290-7. PMID 19100863 DOI: 10.1016/J.Meegid.2008.11.007 |
0.392 |
|
| 2009 |
Alam MZ, Kuhls K, Schweynoch C, Sundar S, Rijal S, Shamsuzzaman AK, Raju BV, Salotra P, Dujardin JC, Schönian G. Multilocus microsatellite typing (MLMT) reveals genetic homogeneity of Leishmania donovani strains in the Indian subcontinent. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 9: 24-31. PMID 18957333 DOI: 10.1016/J.Meegid.2008.09.005 |
0.365 |
|
| 2008 |
Deborggraeve S, Laurent T, Espinosa D, Van der Auwera G, Mbuchi M, Wasunna M, El-Safi S, Al-Basheer AA, Arévalo J, Miranda-Verástegui C, Leclipteux T, Mertens P, Dujardin JC, Herdewijn P, Büscher P. A simplified and standardized polymerase chain reaction format for the diagnosis of leishmaniasis. The Journal of Infectious Diseases. 198: 1565-72. PMID 18816188 DOI: 10.1086/592509 |
0.326 |
|
| 2008 |
Ostyn B, Vanlerberghe V, Picado A, Dinesh DS, Sundar S, Chappuis F, Rijal S, Dujardin JC, Coosemans M, Boelaert M, Davies C. Vector control by insecticide-treated nets in the fight against visceral leishmaniasis in the Indian subcontinent, what is the evidence? Tropical Medicine & International Health : Tm & Ih. 13: 1073-85. PMID 18564350 DOI: 10.1111/J.1365-3156.2008.02110.X |
0.325 |
|
| 2008 |
Mens PF, van Overmeir C, Bonnet M, Dujardin JC, d'Alessandro U. Real-time PCR/MCA assay using fluorescence resonance energy transfer for the genotyping of resistance related DHPS-540 mutations in Plasmodium falciparum. Malaria Journal. 7: 48. PMID 18346279 DOI: 10.1186/1475-2875-7-48 |
0.383 |
|
| 2008 |
Schönian G, Mauricio I, Gramiccia M, Cañavate C, Boelaert M, Dujardin JC. Leishmaniases in the Mediterranean in the era of molecular epidemiology. Trends in Parasitology. 24: 135-42. PMID 18262469 DOI: 10.1016/J.Pt.2007.12.006 |
0.306 |
|
| 2008 |
Decuypere S, Vanaerschot M, Rijal S, Yardley V, Maes L, de Doncker S, Chappuis F, Dujardin JC. Gene expression profiling of Leishmania (Leishmania) donovani: overcoming technical variation and exploiting biological variation. Parasitology. 135: 183-94. PMID 17931458 DOI: 10.1017/S0031182007003782 |
0.708 |
|
| 2007 |
Garcia AL, Tellez T, Parrado R, Rojas E, Bermudez H, Dujardin JC. Epidemiological monitoring of American tegumentary leishmaniasis: molecular characterization of a peridomestic transmission cycle in the Amazonian lowlands of Bolivia. Transactions of the Royal Society of Tropical Medicine and Hygiene. 101: 1208-13. PMID 17945322 DOI: 10.1016/J.Trstmh.2007.09.002 |
0.344 |
|
| 2007 |
Rozas M, De Doncker S, Adaui V, Coronado X, Barnabé C, Tibyarenc M, Solari A, Dujardin JC. Multilocus polymerase chain reaction restriction fragment--length polymorphism genotyping of Trypanosoma cruzi (Chagas disease): taxonomic and clinical applications. The Journal of Infectious Diseases. 195: 1381-8. PMID 17397011 DOI: 10.1086/513440 |
0.347 |
|
| 2007 |
Rijal S, Yardley V, Chappuis F, Decuypere S, Khanal B, Singh R, Boelaert M, De Doncker S, Croft S, Dujardin JC. Antimonial treatment of visceral leishmaniasis: are current in vitro susceptibility assays adequate for prognosis of in vivo therapy outcome? Microbes and Infection / Institut Pasteur. 9: 529-35. PMID 17350306 DOI: 10.1016/j.micinf.2007.01.009 |
0.736 |
|
| 2007 |
Garcia AL, Parrado R, De Doncker S, Bermudez H, Dujardin JC. American tegumentary leishmaniasis: direct species identification of Leishmania in non-invasive clinical samples. Transactions of the Royal Society of Tropical Medicine and Hygiene. 101: 368-71. PMID 17011005 DOI: 10.1016/J.Trstmh.2006.06.009 |
0.326 |
|
| 2007 |
Laurent T, Rijal S, Yardley V, Croft S, De Doncker S, Decuypere S, Khanal B, Singh R, Schönian G, Kuhls K, Chappuis F, Dujardin JC. Epidemiological dynamics of antimonial resistance in Leishmania donovani: genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 7: 206-12. PMID 17010679 DOI: 10.1016/J.Meegid.2006.08.005 |
0.741 |
|
| 2006 |
Yardley V, Ortuno N, Llanos-Cuentas A, Chappuis F, Doncker SD, Ramirez L, Croft S, Arevalo J, Adaui V, Bermudez H, Decuypere S, Dujardin JC. American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility? The Journal of Infectious Diseases. 194: 1168-75. PMID 16991093 DOI: 10.1086/507710 |
0.764 |
|
| 2006 |
Mulenga M, VangGeertruyden JP, Mwananyanda L, Chalwe V, Moerman F, Chilengi R, Van Overmeir C, Dujardin JC, D'Alessandro U. Safety and efficacy of lumefantrine-artemether (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Zambian adults. Malaria Journal. 5: 73. PMID 16923176 DOI: 10.1186/1475-2875-5-73 |
0.344 |
|
| 2006 |
Sádlová J, Volf P, Victoir K, Dujardin JC, Votýpka J. Virulent and attenuated lines of Leishmania major: DNA karyotypes and differences in metalloproteinase GP63 Folia Parasitologica. 53: 81-90. PMID 16898121 DOI: 10.14411/Fp.2006.011 |
0.341 |
|
| 2005 |
Decuypere S, Rijal S, Yardley V, De Doncker S, Laurent T, Khanal B, Chappuis F, Dujardin JC. Gene expression analysis of the mechanism of natural Sb(V) resistance in Leishmania donovani isolates from Nepal. Antimicrobial Agents and Chemotherapy. 49: 4616-21. PMID 16251303 DOI: 10.1128/Aac.49.11.4616-4621.2005 |
0.712 |
|
| 2005 |
Decuypere S, Vandesompele J, Yardley V, De Donckeri S, Laurent T, Rijal S, Llanos-Cuentas A, Chappuis F, Arevalo J, Dujardin JC. Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. Parasitology. 131: 321-9. PMID 16178353 DOI: 10.1017/S0031182005007808 |
0.655 |
|
| 2005 |
Quispe-Tintaya KW, Laurent T, Decuypere S, Hide M, Bañuls AL, De Doncker S, Rijal S, Cañavate C, Campino L, Dujardin JC. Fluorogenic assay for molecular typing of the Leishmania donovani complex: taxonomic and clinical applications. The Journal of Infectious Diseases. 192: 685-92. PMID 16028139 DOI: 10.1086/432077 |
0.691 |
|
| 2005 |
De Doncker S, Hutse V, Abdellati S, Rijal S, Singh Karki BM, Decuypere S, Jacquet D, Le Ray D, Boelaert M, Koirala S, Dujardin JC. A new PCR-ELISA for diagnosis of visceral leishmaniasis in blood of HIV-negative subjects. Transactions of the Royal Society of Tropical Medicine and Hygiene. 99: 25-31. PMID 15550258 DOI: 10.1016/J.Trstmh.2004.01.015 |
0.68 |
|
| 2005 |
NYACHIEO A, LAURENT T, D’ALESSANDRO U, VAN OVERMEIR C, DUJARDIN J. PLASMODIUM FALCIPARUM GENOTYPING BY MICROSATELLITES AS A METHOD TO DISTINGUISH BETWEEN RECRUDESCENT AND NEW INFECTIONS The American Journal of Tropical Medicine and Hygiene. 73: 210-213. DOI: 10.4269/Ajtmh.2005.73.210 |
0.349 |
|
| 2005 |
TINTO H, OUÉDRAOGO JB, ERHART A, VAN OVERMEIR C, GUIGUEMDÉ TR, VAN MARCK E, SANOU B, D’ALESSANDRO U, DUJARDIN J. USEFULNESS OF THE PLASMODIUM FALCIPARUM CHLOROQUINE RESISTANCE TRANSPORTER T76 GENOTYPE FAILURE INDEX FOR THE ESTIMATION OF IN VIVO CHLOROQUINE RESISTANCE IN BURKINA FASO The American Journal of Tropical Medicine and Hygiene. 73: 171-173. DOI: 10.4269/Ajtmh.2005.73.171 |
0.337 |
|
| 2003 |
Decuypere S, Elinck E, Van Overmeir C, Talisuna AO, D'Alessandro U, Dujardin JC. Pathogen genotyping in polyclonal infections: application of a fluorogenic polymerase-chain-reaction assay in malaria. The Journal of Infectious Diseases. 188: 1245-9. PMID 14551896 DOI: 10.1086/378521 |
0.726 |
|
| 2003 |
Victoir K, De Doncker S, Cabrera L, Alvarez E, Arevalo J, Llanos-Cuentas A, Le Ray D, Dujardin JC. Direct identification of Leishmania species in biopsies from patients with American tegumentary leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 97: 80-7. PMID 12886810 DOI: 10.1016/S0035-9203(03)90031-9 |
0.365 |
|
| 2002 |
Victoir K, Dujardin JC. How to succeed in parasitic life without sex? Asking Leishmania Trends in Parasitology. 18: 81-85. PMID 11832299 DOI: 10.1016/S1471-4922(01)02199-7 |
0.331 |
|
| 2000 |
Dujardin JC, Henriksson J, Victoir K, Brisse S, Gamboa D, Arevalo J, Le Ray D. Genomic rearrangements in trypanosomatids: an alternative to the "one gene" evolutionary hypotheses? Memã³Rias Do Instituto Oswaldo Cruz. 95: 527-34. PMID 10904411 DOI: 10.1590/S0074-02762000000400015 |
0.332 |
|
| 2000 |
Bañuls AL, Dujardin JC, Guerrini F, De Doncker S, Jacquet D, Arevalo J, Noël S, Le Ray D, Tibayrenc M. Is Leishmania (Viannia) peruviana a distinct species? A MLEE/RAPD evolutionary genetics answer. The Journal of Eukaryotic Microbiology. 47: 197-207. PMID 10847336 DOI: 10.1111/J.1550-7408.2000.Tb00039.X |
0.326 |
|
| 2000 |
Guerbouj S, Guizani I, Victoir K, Le Ray D, Dujardin JC. Parasite candidate vaccines: a warning from polymorphic Leishmania populations. Parasitology Today (Personal Ed.). 16: 265. PMID 10827439 DOI: 10.1016/S0169-4758(00)01682-3 |
0.318 |
|
| 1995 |
Dujardin JC, Bañuls AL, Llanos-Cuentas A, Alvarez E, DeDoncker S, Jacquet D, Le Ray D, Arevalo J, Tibayrenc M. Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru. Acta Tropica. 59: 293-307. PMID 8533665 DOI: 10.1016/0001-706X(95)00094-U |
0.334 |
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