| Year |
Citation |
Score |
| 2024 |
Nag S, Jia K, Arakawa R, Datta P, Scott D, Shaffer C, Moein MM, Hutchison M, Kaliszczak M, Halldin C. Synthesis of [C]BIIB104, an α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic-Acid-Positive Allosteric Modulator, and Evaluation of the Bio-Distribution in Non-Human Primate Brains Using Positron Emission Tomography. Molecules (Basel, Switzerland). 29. PMID 38257338 DOI: 10.3390/molecules29020427 |
0.379 |
|
| 2023 |
Cook BE, Nag S, Arakawa R, Lin EY, Stratman N, Guckian K, Hering H, Lulla M, Choi J, Salinas C, Genung NE, Morén AF, Bolin M, Boscutti G, Plisson C, ... ... Halldin C, et al. Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 64: 1588-1593. PMID 37934021 DOI: 10.2967/jnumed.122.265225 |
0.369 |
|
| 2023 |
Schou M, Amini N, Takano A, Arakawa R, Dahl K, Toth M, Svedberg M, Varrone A, Halldin C. Microsome Mediated in Vitro Metabolism: A Convenient Method for the Preparation of the PET Radioligand Metabolite [F]FE-PE2I-OH for Translational Dopamine Transporter Imaging. Acs Chemical Neuroscience. 14: 3732-3736. PMID 37753876 DOI: 10.1021/acschemneuro.3c00458 |
0.308 |
|
| 2023 |
Varnäs K, Nag S, Halldin C, Farde L. PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain. Acs Chemical Neuroscience. PMID 37587571 DOI: 10.1021/acschemneuro.3c00332 |
0.323 |
|
| 2023 |
Cook BE, Nag S, Arakawa R, Lin EY, Stratman N, Guckian K, Hering H, Lulla M, Choi J, Salinas C, Genung NE, Morén AF, Bolin M, Boscutti G, Plisson C, ... ... Halldin C, et al. Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 37414448 DOI: 10.2967/jnumed.122.265225 |
0.369 |
|
| 2023 |
Nag S, Bolin M, Datta P, Arakawa R, Forsberg Morén A, Khani Maynaq Y, Lin E, Genung N, Hering H, Guckian K, Martarello L, Kaliszczak M, Halldin C. Development of a Novel [C]CO-Labeled Positron Emission Tomography Radioligand [C]BIO-1819578 for the Detection of -GlcNAcase Enzyme Activity. Acs Chemical Neuroscience. PMID 37377046 DOI: 10.1021/acschemneuro.3c00247 |
0.409 |
|
| 2023 |
Nag S, Arakawa R, Jia Z, Lachapelle E, Zhang L, Maresca K, Chen L, Jahan M, Mccarthy T, Halldin C. Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP). Molecules (Basel, Switzerland). 28. PMID 37375167 DOI: 10.3390/molecules28124612 |
0.412 |
|
| 2022 |
Liu L, Johnson PD, Prime ME, Khetarpal V, Brown CJ, Anzillotti L, Bertoglio D, Chen X, Coe S, Davis R, Dickie AP, Esposito S, Gadouleau E, Giles PR, Greenaway C, ... ... Halldin C, et al. Design and Evaluation of [F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates. Journal of Medicinal Chemistry. PMID 36548390 DOI: 10.1021/acs.jmedchem.2c01585 |
0.336 |
|
| 2022 |
Brumberg J, Aarnio R, Forsberg A, Marjamäki P, Kerstens V, Moein MM, Nag S, Wahlroos S, Kassiou M, Windhorst AD, Halldin C, Haaparanta-Solin M, Fazio P, Oikonen V, Rinne JO, et al. Quantification of the purinergic P2X receptor with [C]SMW139 improves through correction for brain-penetrating radiometabolites. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221126830. PMID 36163685 DOI: 10.1177/0271678X221126830 |
0.337 |
|
| 2022 |
Svensson JE, Tiger M, Plavén-Sigray P, Halldin C, Schain M, Lundberg J. In vivo correlation of serotonin transporter and 1B receptor availability in the human brain: a PET study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35821068 DOI: 10.1038/s41386-022-01369-3 |
0.323 |
|
| 2022 |
Dahl K, Johnström P, Forsberg-Morén A, Gustafsson B, Miranda-Azpiazu P, Khani Y, Halldin C, Farde L, Elmore CS, Schou M. Synthesis and Preclinical Evaluation of [C]AZ11895530 for PET Imaging of the Serotonin 1A Receptor. Acs Chemical Neuroscience. PMID 35802379 DOI: 10.1021/acschemneuro.2c00205 |
0.412 |
|
| 2022 |
Wakabayashi Y, Strenkona P, Arakawa R, Yan X, Van Buskirk MG, Jenkins MD, Montero Santamaria JA, Maresca KP, Takano A, Liow JS, Chappie TA, Varrone A, Nag S, Zhang L, Hughes ZA, ... ... Halldin C, et al. First-in-human evaluation of F-PF-06445974, a PET radioligand that preferentially labels phosphodiesterase-4B. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35772961 DOI: 10.2967/jnumed.122.263838 |
0.341 |
|
| 2022 |
Arakawa R, Takano A, Nag S, Jia Z, Amini N, Maresca KP, Zhang L, Keliher EJ, Butler CR, Piro JR, Samad TA, Smith D, Nason D, O'Neil S, Trapa P, ... ... Halldin C, et al. Target occupancy study and whole-body dosimetry with a MAGL PET ligand [C]PF-06809247 in non-human primates. Ejnmmi Research. 12: 13. PMID 35244788 DOI: 10.1186/s13550-022-00882-2 |
0.335 |
|
| 2022 |
Nag S, Miranda-Azpiazu P, Jia Z, Datta P, Arakawa R, Moein MM, Yang Z, Tu Y, Lemoine L, Ågren H, Nordberg A, Långström B, Halldin C. Development of C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR). Acs Chemical Neuroscience. PMID 35020351 DOI: 10.1021/acschemneuro.1c00730 |
0.334 |
|
| 2021 |
Veldman ER, Varrone A, Varnäs K, Svedberg MM, Cselényi Z, Tiger M, Gulyás B, Halldin C, Lundberg J. Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211049185. PMID 34644198 DOI: 10.1177/0271678X211049185 |
0.587 |
|
| 2021 |
Liu L, Johnson PD, Prime ME, Khetarpal V, Lee MR, Brown CJ, Chen X, Clark-Frew D, Coe S, Conlon M, Davis R, Ensor S, Esposito S, Moren AF, Gai X, ... ... Halldin C, et al. [C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins. Journal of Medicinal Chemistry. PMID 34351166 DOI: 10.1021/acs.jmedchem.1c00667 |
0.303 |
|
| 2021 |
Kanta Ghosh K, Padmanabhan P, Yang CT, Chee Eng Ng D, Palanivel M, Mishra S, Halldin C, Gulyás B. Positron emission tomographic imaging in drug discovery. Drug Discovery Today. PMID 34332093 DOI: 10.1016/j.drudis.2021.07.025 |
0.505 |
|
| 2021 |
Ghosh KK, Padmanabhan P, Yang CT, Wang Z, Palanivel M, Ng KC, Lu J, Carlstedt-Duke J, Halldin C, Gulyás B. An In Vivo Study of a Rat Fluid-Percussion-Induced Traumatic Brain Injury Model with [C]PBR28 and [F]flumazenil PET Imaging. International Journal of Molecular Sciences. 22. PMID 33477960 DOI: 10.3390/ijms22020951 |
0.573 |
|
| 2020 |
Vanan S, Zeng X, Chia SY, Varnäs K, Jiang M, Zhang K, Saw WT, Padmanabhan P, Yu WP, Zhou ZD, Halldin C, Gulyás B, Tan EK, Zeng L. Altered striatal dopamine levels in Parkinson's disease VPS35 D620N mutant transgenic aged mice. Molecular Brain. 13: 164. PMID 33261640 DOI: 10.1186/s13041-020-00704-3 |
0.449 |
|
| 2020 |
Varnäs K, Finnema SJ, Johnström P, Arakawa R, Halldin C, Eriksson LI, Farde L. Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo. British Journal of Anaesthesia. PMID 33036760 DOI: 10.1016/j.bja.2020.08.052 |
0.334 |
|
| 2020 |
Ghosh KK, Padmanabhan P, Yang CT, Mishra S, Halldin C, Gulyás B. Dealing with PET radiometabolites. Ejnmmi Research. 10: 109. PMID 32997213 DOI: 10.1186/s13550-020-00692-4 |
0.566 |
|
| 2020 |
Moein MM, Halldin C. Sample preparation techniques for protein binding measurement in radiopharmaceutical approaches: A short review. Talanta. 219: 121220. PMID 32887121 DOI: 10.1016/J.Talanta.2020.121220 |
0.376 |
|
| 2020 |
Andersson M, Tangen Ä, Farde L, Bölte S, Halldin C, Borg J, Lundberg J. Serotonin transporter availability in adults with autism-a positron emission tomography study. Molecular Psychiatry. PMID 32848204 DOI: 10.1038/S41380-020-00868-3 |
0.309 |
|
| 2020 |
Kerstens VS, Fazio P, Sundgren M, Matheson GJ, Franzén E, Halldin C, Cervenka S, Svenningsson P, Varrone A. Reliability of dopamine transporter PET measurements with [F]FE-PE2I in patients with Parkinson's disease. Ejnmmi Research. 10: 95. PMID 32797307 DOI: 10.1186/S13550-020-00676-4 |
0.346 |
|
| 2020 |
Liu L, Prime ME, Lee MR, Khetarpal V, Brown CJ, Johnson PD, Azpiazu P, Chen A, Clark-Frew D, Coe S, Davis R, Dickie A, Ebneth A, Esposito S, Gadouleau E, ... ... Halldin C, et al. Imaging Mutant Huntingtin Aggregates: Development of a Potential PET ligand. Journal of Medicinal Chemistry. PMID 32662649 DOI: 10.1021/Acs.Jmedchem.0C00955 |
0.456 |
|
| 2020 |
Ferrat M, El Khoury Y, Larsen P, Dahl K, Halldin C, Schou M. Development of a Fully Automated Low Pressure [ C]CO Carbonylation Apparatus. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 32588452 DOI: 10.1002/Jlcr.3866 |
0.398 |
|
| 2020 |
Cselényi Z, Jucaite A, Kristensson C, Stenkrona P, Ewing P, Varrone A, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Bolin M, Siikanen J, Grybäck P, Larsson B, Halldin C, et al. Quantification and reliability of [C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung - a test-retest PET study in control subjects. Ejnmmi Research. 10: 59. PMID 32495011 DOI: 10.1186/S13550-020-00634-0 |
0.414 |
|
| 2020 |
Tiger M, Veldman ER, Ekman CJ, Halldin C, Svenningsson P, Lundberg J. A randomized placebo-controlled PET study of ketamine´s effect on serotonin receptor binding in patients with SSRI-resistant depression. Translational Psychiatry. 10: 159. PMID 32475989 DOI: 10.1038/S41398-020-0844-4 |
0.381 |
|
| 2020 |
Varnäs K, Stepanov V, Halldin C. Autoradiographic mapping of synaptic vesicle glycoprotein 2A in non-human primate and human brain. Synapse (New York, N.Y.). PMID 32259300 DOI: 10.1002/Syn.22157 |
0.472 |
|
| 2020 |
Nag S, Varnas K, Arakawa R, Jahan M, Schou M, Farde L, Halldin C. Synthesis, biodistribution and radiation dosimetry of a novel mGluR5 radioligand: [18F]AZD9272. Acs Chemical Neuroscience. PMID 32167745 DOI: 10.1021/Acschemneuro.9B00680 |
0.493 |
|
| 2020 |
Arakawa R, Takano A, Stenkrona P, Stepanov V, Nag S, Jahan M, Grybäck P, Bolin M, Chen L, Zhang L, He P, Villalobos A, McCarthy TJ, Halldin C, Varrone A. PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [F]PF-06684511. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32140803 DOI: 10.1007/S00259-020-04739-5 |
0.427 |
|
| 2020 |
Knudsen GM, Ganz M, Appelhoff S, Boellaard R, Bormans G, Carson RE, Catana C, Doudet D, Gee AD, Greve DN, Gunn RN, Halldin C, Herscovitch P, Huang H, Keller SH, et al. Guidelines for the content and format of PET brain data in publications and archives: A consensus paper. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20905433. PMID 32065076 DOI: 10.1177/0271678X20905433 |
0.369 |
|
| 2020 |
Fazio P, Ferreira D, Svenningsson P, Halldin C, Farde L, Westman E, Varrone A. High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson's disease cohort. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32020370 DOI: 10.1007/S00259-020-04683-4 |
0.363 |
|
| 2020 |
Tiger M, Svensson J, Liberg B, Saijo T, Schain M, Halldin C, Farde L, Lundberg J. A [ C]raclopride positron emission tomography study of dopamine-D receptor binding in patients with severe major depressive episodes before and after electroconvulsive therapy and compared to control subjects. Psychiatry and Clinical Neurosciences. PMID 31943514 DOI: 10.1111/Pcn.12980 |
0.373 |
|
| 2020 |
Moein MM, Tóth M, Tari L, Varrone A, Abdel-Rehim M, Halldin C. New approach in radiometabolite analysis of positron emission tomography (PET) radioligands; lead-shielded microextraction by packed sorbent as a tool for in vivo radiometabolite analysis of [C]SMW139 in rat plasma. Talanta. 208: 120449. PMID 31816716 DOI: 10.1016/J.Talanta.2019.120449 |
0.44 |
|
| 2020 |
Victorsson P, Plavén-Sigray P, Matheson G, Santillo A, Lee M, Collste K, Fatouros-Bergman H, Agartz I, Halldin C, Farde L, Cervenka S. M7. LOWER THALAMIC DOPAMINE D2-RECEPTOR BINDING IN DRUG-NAIVE PATIENTS WITH PSYCHOSIS – A REPLICATION STUDY USING POSITRON EMISSION TOMOGRAPHY Schizophrenia Bulletin. 46: S135-S136. DOI: 10.1093/Schbul/Sbaa030.319 |
0.422 |
|
| 2019 |
Svensson JE, Schain M, Plavén-Sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J. In response to the letter "[C]raclopride and extrastriatal binding to D2/3 receptors". Neuroimage. 116371. PMID 31756518 DOI: 10.1016/J.Neuroimage.2019.116371 |
0.407 |
|
| 2019 |
Lindberg A, Arakawa R, Nogami T, Nag S, Schou M, Elmore CS, Farde L, Pike VW, Halldin C. Potential for imaging the high-affinity state of the 5-HT receptor: a comparison of three PET radioligands with differing intrinsic activity. Ejnmmi Research. 9: 100. PMID 31754940 DOI: 10.1186/S13550-019-0570-1 |
0.39 |
|
| 2019 |
Jhao YT, Chiu CH, Chen CF, Chou TK, Lin YW, Ju YT, Wu SC, Yan RF, Shiue CY, Chueh SH, Halldin C, Cheng CY, Ma KH. The Effect of Sertoli Cells on Xenotransplantation and Allotransplantation of Ventral Mesencephalic Tissue in a Rat Model of Parkinson's Disease. Cells. 8. PMID 31718058 DOI: 10.3390/Cells8111420 |
0.309 |
|
| 2019 |
Lindberg A, Nag S, Schou M, Arakawa R, Nogami T, Moein MM, Elmore CS, Pike VW, Halldin C. Development of a F-labeled PET radioligand for imaging 5-HT receptors: [F]AZ10419096. Nuclear Medicine and Biology. 78: 11-16. PMID 31678782 DOI: 10.1016/J.Nucmedbio.2019.10.003 |
0.462 |
|
| 2019 |
Varnäs K, Cselényi Z, Arakawa R, Nag S, Stepanov V, Moein MM, Johnström P, Kingston L, Elmore CS, Halldin C, Farde L. The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans. Neuropharmacology. 107809. PMID 31589885 DOI: 10.1016/J.Neuropharm.2019.107809 |
0.455 |
|
| 2019 |
Ferrat M, Dahl K, Halldin C, Schou M. "In-loop" carbonylation - a simplified method for carbon-11 labeling of drugs and radioligands. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 31524295 DOI: 10.1002/Jlcr.3805 |
0.42 |
|
| 2019 |
Zhang L, Butler CR, Maresca KP, Takano A, Nag S, Jia Z, Arakawa R, Piro J, Samad T, Smith DL, Nason DM, O'Neil SV, McAllister LA, Schildknegt K, Trapa P, ... ... Halldin C, et al. Identification and development of an irreversible monoacylglycerol lipase (MAGL) positron emission tomography (PET) radioligand with high specificity. Journal of Medicinal Chemistry. PMID 31483137 DOI: 10.1021/Acs.Jmedchem.9B00847 |
0.452 |
|
| 2019 |
Svensson JE, Schain M, Plavén-Sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J. Validity and reliability of extrastriatal [C]raclopride binding quantification in the living human brain. Neuroimage. 116143. PMID 31473354 DOI: 10.1016/J.Neuroimage.2019.116143 |
0.463 |
|
| 2019 |
Tuisku J, Plavén-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Brück A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, et al. Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C]PBR28 HRRT PET study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31363804 DOI: 10.1007/S00259-019-04403-7 |
0.385 |
|
| 2019 |
Sarnyai Z, Nagy K, Patay G, Molnár M, Rosenqvist G, Tóth M, Takano A, Gulyás B, Major P, Halldin C, Varrone A. Performance Evaluation of a High Resolution Non-Human Primate PET/CT System. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31302634 DOI: 10.2967/Jnumed.117.206243 |
0.596 |
|
| 2019 |
Forsberg A, Lampa J, Estelius J, Cervenka S, Farde L, Halldin C, Lekander M, Olgart Höglund C, Kosek E. Disease activity in rheumatoid arthritis is inversely related to cerebral TSPO binding assessed by [C]PBR28 positron emission tomography. Journal of Neuroimmunology. 334: 577000. PMID 31260948 DOI: 10.1016/J.Jneuroim.2019.577000 |
0.328 |
|
| 2019 |
Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Bundgaard C, Bang-Andersen B, Sanchez C, Halldin C, Farde L, Finnema SJ. Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31216565 DOI: 10.1038/S41386-019-0442-4 |
0.431 |
|
| 2019 |
Dahl K, Bernard-Gauthier V, Nag S, Varnäs K, Narayanaswami V, Mahdi Moein M, Arakawa R, Vasdev N, Halldin C. Synthesis and preclinical evaluation of [F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B. Bioorganic & Medicinal Chemistry Letters. PMID 31060887 DOI: 10.1016/J.Bmcl.2019.04.040 |
0.415 |
|
| 2019 |
Varrone A, Varnäs K, Jucaite A, Cselényi Z, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Halldin C, Brown AP, Vishwanathan K, Farde L. A PET study in healthy subjects of brain exposure of C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19843776. PMID 31006308 DOI: 10.1177/0271678X19843776 |
0.441 |
|
| 2019 |
Stenkrona P, Matheson GJ, Halldin C, Cervenka S, Farde L. D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients. The International Journal of Neuropsychopharmacology. PMID 30958880 DOI: 10.1093/Ijnp/Pyz017 |
0.41 |
|
| 2019 |
Lindberg A, Lu S, Nag S, Schou M, Liow JS, Zoghbi SS, Frankland MP, Gladding RL, Morse CL, Takano A, Amini N, Elmore CS, Lee YS, Innis RB, Halldin C, et al. Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT receptors. Nuclear Medicine and Biology. 70: 1-13. PMID 30811975 DOI: 10.1016/J.Nucmedbio.2019.01.005 |
0.451 |
|
| 2019 |
Schou M, Ewing P, Cselenyi Z, Fridén M, Takano A, Halldin C, Farde L. Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator. Ejnmmi Research. 9: 9. PMID 30694407 DOI: 10.1186/S13550-019-0479-8 |
0.397 |
|
| 2019 |
Svedberg MM, Varnäs K, Varrone A, Mitsios N, Mulder J, Gulyás B, Beaumont V, Munoz-Sanjuan I, Zaleska MM, Schmidt CJ, Halldin C, Mrzljak L. In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [F]MNI-659. Brain Research. PMID 30664847 DOI: 10.1016/J.Brainres.2019.01.021 |
0.603 |
|
| 2019 |
Arakawa R, Stenkrona P, Takano A, Svensson J, Andersson M, Nag S, Asami Y, Hirano Y, Halldin C, Lundberg J. Venlafaxine ER blocks the norepinephrine transporter in the brain of patients with major depressive disorder: a PET study using [18F]FMeNER-D2. The International Journal of Neuropsychopharmacology. PMID 30649319 DOI: 10.1093/Ijnp/Pyz003 |
0.417 |
|
| 2019 |
Moein MM, Nakao R, Amini N, Abdel-Rehim M, Schou M, Halldin C. Sample preparation techniques for radiometabolite analysis of positron emission tomography radioligands; trends, progress, limitations and future prospects Trends in Analytical Chemistry. 110: 1-7. DOI: 10.1016/J.Trac.2018.10.019 |
0.348 |
|
| 2019 |
Darreh-Shori T, Kumar R, Kumar A, Murumkar P, Nag S, Jia Z, Arakawa R, Leuzy A, Lemoine L, Nordberg A, Yadav MR, Halldin C, Långström B. LIGANDS OF THE CORE ACETYLCHOLINE BIOSYNTHESIZING ENZYME, CHOLINE ACETYLTRANSFERASE, AS NOVEL AND POTENTIAL THERAPEUTIC AGENTS AND IN VIVO PET TRACERS FOR EARLY DIAGNOSIS OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P1630. DOI: 10.1016/J.Jalz.2019.06.4869 |
0.328 |
|
| 2019 |
Arakawa R, Stenkrona P, Takano A, Svensson J, Andersson M, Nag S, Asami Y, Halldin C, Lundberg J. Norepinephrine transporter occupancy of venlafaxine in patients with major depressive disorder using positron emission tomography and [18F]FMeNER-D2 European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.497 |
0.352 |
|
| 2018 |
Yang CT, Ghosh KK, Padmanabhan P, Langer O, Liu J, Eng DNC, Halldin C, Gulyás B. PET-MR and SPECT-MR multimodality probes: Development and challenges. Theranostics. 8: 6210-6232. PMID 30613293 DOI: 10.7150/Thno.26610 |
0.556 |
|
| 2018 |
Jahan M, Johnström P, Selvaraju RK, Svedberg M, Winzell MS, Bernström J, Kingston L, Schou M, Jia Z, Skrtic S, Johansson L, Korsgren O, Farde L, Halldin C, Eriksson O. The development of a GPR44 targeting radioligand [C]AZ12204657 for in vivo assessment of beta cell mass. Ejnmmi Research. 8: 113. PMID 30588560 DOI: 10.1186/S13550-018-0465-6 |
0.304 |
|
| 2018 |
Takano A, Chen L, Nag S, Brodney MA, Arakawa R, Chang C, Amini N, Doran SD, Dutra JK, McCarthy TJ, Nolan CE, O'Neill BT, Villalobos A, Zhang L, Halldin C. Quantitative Analysis of F-PF-06684511, a Novel PET Radioligand for Selective β-secretase 1 Imaging, in Non-human Primate Brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30530832 DOI: 10.2967/Jnumed.118.217372 |
0.47 |
|
| 2018 |
Arakawa R, Takano A, Halldin C. Serotonin and norepinephrine transporter occupancy of tramadol in non-human primate using positron emission tomography. The International Journal of Neuropsychopharmacology. PMID 30346535 DOI: 10.1093/Ijnp/Pyy089 |
0.363 |
|
| 2018 |
Varnäs K, Cselényi Z, Jucaite A, Halldin C, Svenningsson P, Farde L, Varrone A. PET imaging of [C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30270409 DOI: 10.1007/S00259-018-4161-6 |
0.387 |
|
| 2018 |
Albrecht DS, Forsberg A, Sandstrom A, Bergan C, Kadetoff D, Protsenko E, Lampa J, Lee YC, Höglund CO, Catana C, Cervenka S, Akeju O, Lekander M, Cohen G, Halldin C, et al. Brain glial activation in fibromyalgia - a multi-site positron emission tomography investigation. Brain, Behavior, and Immunity. PMID 30223011 DOI: 10.1016/J.Bbi.2018.09.018 |
0.452 |
|
| 2018 |
Stenkrona P, Matheson GJ, Cervenka S, Sigray PP, Halldin C, Farde L. [C]SCH23390 binding to the D-dopamine receptor in the human brain-a comparison of manual and automated methods for image analysis. Ejnmmi Research. 8: 74. PMID 30069645 DOI: 10.1186/S13550-018-0416-2 |
0.465 |
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| 2018 |
Takano A, Nag S, Jia Z, Jahan M, Forsberg A, Arakawa R, Grybäck P, Duvey G, Halldin C, Charvin D. Characterization of [C]PXT012253 as a PET Radioligand for mGlu Allosteric Modulators in Nonhuman Primates. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 30066121 DOI: 10.1007/S11307-018-1257-0 |
0.457 |
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| 2018 |
Yang KC, Takano A, Halldin C, Farde L, Finnema SJ. Serotonin concentration enhancers at clinically relevant doses reduce [C]AZ10419369 binding to the 5-HT receptors in the nonhuman primate brain. Translational Psychiatry. 8: 132. PMID 30013068 DOI: 10.1038/S41398-018-0178-7 |
0.445 |
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| 2018 |
Chiotis K, Stenkrona P, Almkvist O, Stepanov V, Ferreira D, Arakawa R, Takano A, Westman E, Varrone A, Okamura N, Shimada H, Higuchi M, Halldin C, Nordberg A. Dual tracer tau PET imaging reveals different molecular targets for C-THK5351 and C-PBB3 in the Alzheimer brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 29752516 DOI: 10.1007/S00259-018-4012-5 |
0.458 |
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| 2018 |
Varnäs K, Juréus A, Finnema SJ, Johnström P, Raboisson P, Amini N, Takano A, Stepanov V, Halldin C, Farde L. The metabotropic glutamate receptor 5 radioligand [C]AZD9272 identifies unique binding sites in primate brain. Neuropharmacology. PMID 29608920 DOI: 10.1016/J.Neuropharm.2018.03.039 |
0.455 |
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| 2018 |
Plavén-Sigray P, Matheson GJ, Gustavsson P, Stenkrona P, Halldin C, Farde L, Cervenka S. Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study. Plos One. 13: e0193770. PMID 29543812 DOI: 10.1371/Journal.Pone.0193770 |
0.394 |
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| 2018 |
Takano A, Uz T, Garcia-Segovia J, Tsai M, Lahu G, Amini N, Nakao R, Jia Z, Halldin C. A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[C]Rolipram. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 29441434 DOI: 10.1007/S11307-018-1168-0 |
0.376 |
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| 2018 |
Fazio P, Svenningsson P, Cselényi Z, Halldin C, Farde L, Varrone A. Nigrostriatal dopamine transporter availability in early Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29436751 DOI: 10.1002/Mds.27316 |
0.316 |
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| 2018 |
Zhang L, Chen L, Dutra JK, Beck EM, Nag S, Takano A, Amini N, Arakawa R, Brodney MA, Buzon LM, Doran SD, Lanyon LF, McCarthy TJ, Bales KR, Nolan CE, ... ... Halldin C, et al. Identification of a novel positron emission tomography (PET) ligand for imaging β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) in brain. Journal of Medicinal Chemistry. PMID 29356535 DOI: 10.1021/Acs.Jmedchem.7B01769 |
0.41 |
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| 2018 |
Lizana H, Johansson L, Axelsson JE, Larsson Strömvall A, Ögren M, Linder J, Halldin C, Varrone A, Mo SJ. Whole-body biodistribution and dosimetry of the dopamine transporter radioligand 18F-FE-PE2I in human subjects. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29348315 DOI: 10.2967/Jnumed.117.197186 |
0.399 |
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| 2018 |
Vishwanathan K, Varrone A, Varnas K, Jucaite A, Cselenyi Z, Johnstrom P, Schou M, Vasquez-Romero A, Moein MM, Halldin C, Brown AP, Farde L. Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with 11C-labelled osimertinib Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ct013 |
0.413 |
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| 2017 |
Odano I, Varrone A, Hosoya T, Sakaguchi K, Gulyás B, Padmanabhan P, Ghosh KK, Yang CT, Guenther I, Wang Z, Serrano R, Chimon NG, Halldin C. Simplified estimation of binding parameters based on image-derived reference tissue models for dopamine transporter bindings in non-human primates using [18F]FE-PE2I and PET. American Journal of Nuclear Medicine and Molecular Imaging. 7: 246-254. PMID 29348979 |
0.515 |
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| 2017 |
Lemoine L, Gillberg PG, Svedberg M, Stepanov V, Jia Z, Huang J, Nag S, Tian H, Ghetti B, Okamura N, Higuchi M, Halldin C, Nordberg A. Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains. Alzheimer's Research & Therapy. 9: 96. PMID 29229003 DOI: 10.1186/S13195-017-0325-Z |
0.418 |
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| 2017 |
Stepanov V, Takano A, Nakao R, Amini N, Miura S, Hasui T, Kimura H, Taniguchi T, Halldin C. Development of two fluorine-18 labeled PET radioligands targeting PDE10A and in vivo PET evaluation in nonhuman primates. Nuclear Medicine and Biology. 57: 12-19. PMID 29223715 DOI: 10.1016/J.Nucmedbio.2017.10.004 |
0.414 |
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| 2017 |
Eriksson O, Johnström P, Cselenyi Z, Jahan M, Selvaraju RK, Jensen-Waern M, Takano A, Winzell MS, Halldin C, Skrtic S, Korsgren O. In Vivo Visualization of Beta Cells by Targeting of GPR44. Diabetes. PMID 29208633 DOI: 10.2337/Db17-0764 |
0.314 |
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| 2017 |
Lindberg A, Nag S, Schou M, Takano A, Matsumoto J, Amini N, Elmore CS, Farde L, Pike VW, Halldin C. [(11)C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors. Nuclear Medicine and Biology. 54: 34-40. PMID 28950161 DOI: 10.1016/J.Nucmedbio.2017.07.007 |
0.508 |
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| 2017 |
Yang KC, Stepanov V, Martinsson S, Ettrup A, Takano A, Knudsen GM, Halldin C, Farde L, Finnema SJ. Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain. The International Journal of Neuropsychopharmacology. 20: 683-691. PMID 28911007 DOI: 10.1093/Ijnp/Pyx051 |
0.49 |
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| 2017 |
Dahl K, Ulin J, Schou M, Halldin C. Reduction of [(11) C]CO2 to [(11) C]CO Using Solid Supported Zinc. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 28868618 DOI: 10.1002/Jlcr.3561 |
0.312 |
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| 2017 |
Schain M, Fazio P, Mrzljak L, Amini N, Al-Tawil N, Fitzer-Attas C, Bronzova J, Landwehrmeyer B, Sampaio C, Halldin C, Varrone A. Revisiting the Logan plot to account for non-negligible blood volume in brain tissue. Ejnmmi Research. 7: 66. PMID 28822101 DOI: 10.1186/S13550-017-0314-Z |
0.321 |
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| 2017 |
Tangen Ä, Borg J, Tiger M, Varnäs K, Sorjonen K, Lindefors N, Halldin C, Lundberg J. Associations between cognition and serotonin receptor 1B binding in patients with major depressive disorder - A pilot study. Psychiatry Research. 267: 15-21. PMID 28688337 DOI: 10.1016/J.Pscychresns.2017.06.001 |
0.328 |
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| 2017 |
Arakawa R, Stenkrona P, Takano A, Nag S, Maior RS, Halldin C. Test-retest reproducibility of [(11)C]-L-deprenyl-D2 binding to MAO-B in the human brain. Ejnmmi Research. 7: 54. PMID 28634836 DOI: 10.1186/S13550-017-0301-4 |
0.457 |
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| 2017 |
Dahl K, Halldin C, Schou M. New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals. Clinical and Translational Imaging. 5: 275-289. PMID 28596949 DOI: 10.1007/S40336-017-0223-1 |
0.368 |
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| 2017 |
Jayaram-Lindström N, Guterstam J, Häggkvist J, Ericson M, Malmlöf T, Schilström B, Halldin C, Cervenka S, Saijo T, Nordström AL, Franck J. Naltrexone modulates dopamine release following chronic, but not acute amphetamine administration: a translational study. Translational Psychiatry. 7: e1104. PMID 28440810 DOI: 10.1038/Tp.2017.79 |
0.313 |
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| 2017 |
Matheson GJ, Stenkrona P, Cselényi Z, Plavén-Sigray P, Halldin C, Farde L, Cervenka S. Reliability of Volumetric and Surface-Based Normalisation and Smoothing Techniques for PET Analysis of the Cortex: A Test-Retest Analysis using [(11)C]SCH-23390. Neuroimage. PMID 28419852 DOI: 10.1016/J.Neuroimage.2017.04.031 |
0.372 |
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| 2017 |
Plavén-Sigray P, Hedman E, Victorsson P, Matheson GJ, Forsberg A, Djurfeldt DR, Rück C, Halldin C, Lindefors N, Cervenka S. Extrastriatal dopamine D2-receptor availability in social anxiety disorder. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 28377075 DOI: 10.1016/J.Euroneuro.2017.03.007 |
0.387 |
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| 2017 |
Fazio P, Schain M, Mrzljak L, Amini N, Nag S, Al-Tawil N, Fitzer-Attas CJ, Bronzova J, Landwehrmeyer B, Sampaio C, Halldin C, Varrone A. Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D2/3 receptors and sub-cortical volumes in the human basal ganglia: a PET study with (18)F-MNI-659 and (11)C-raclopride with correction for partial volume effect. Neuroimage. PMID 28254508 DOI: 10.1016/J.Neuroimage.2017.02.047 |
0.414 |
|
| 2017 |
Forsberg A, Cervenka S, Jonsson Fagerlund M, Rasmussen LS, Zetterberg H, Erlandsson Harris H, Stridh P, Christensson E, Granström A, Schening A, Dymmel K, Knave N, Terrando N, Maze M, Borg J, ... ... Halldin C, et al. The immune response of the human brain to abdominal surgery. Annals of Neurology. PMID 28253549 DOI: 10.1002/Ana.24909 |
0.327 |
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| 2017 |
Delnomdedieu M, Forsberg A, Ogden A, Fazio P, Yu CR, Stenkrona P, Duvvuri S, David W, Al-Tawil N, Vitolo OV, Amini N, Nag S, Halldin C, Varrone A. In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects. Neuropharmacology. PMID 28122201 DOI: 10.1016/J.Neuropharm.2017.01.016 |
0.313 |
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| 2017 |
Kuang G, Zhou Y, Zou R, Halldin C, Nordberg A, Långström B, Ågren H, Tu Y. Characterization of the binding mode of the PET tracer [18F]ASEM to a chimera structure of the α7 nicotinic acetylcholine receptor Rsc Advances. 7: 19787-19793. DOI: 10.1039/C7Ra00496F |
0.366 |
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| 2017 |
Andersson M, Horder J, Mendez M, Tangen A, Lundberg J, Gee A, Halldin C, Veronese M, Bölte S, Sementa T, Cash D, Turkheimer F, Mick S, Selvaraj S, Nutt D, et al. A multicenter positron emission tomography study of GABA receptor availability in adults with autism European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)31321-4 |
0.339 |
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| 2017 |
Chiotis K, Stenkrona P, Almkvist O, Arakawa R, Takano A, Stepanov V, Varrone A, Higuchi M, Halldin C, Nordberg A. [IC-P-178]: HEAD-TO-HEAD IN VIVO
COMPARISON OF TAU-SPECIFIC PET TRACERS IN ALZHEIMER's DISEASE: [11
C]THK5351 VERSUS [11
C]PBB3 PET IMAGING Alzheimer's & Dementia. 13: P133-P133. DOI: 10.1016/J.Jalz.2017.06.2553 |
0.411 |
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| 2017 |
Yang C, Ghosh KK, Padmanabhan P, Langer O, Liu J, Halldin C, Gulyás BZ. PET probes for imaging pancreatic islet cells Clinical and Translational Imaging. 5: 507-523. DOI: 10.1007/S40336-017-0251-X |
0.559 |
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| 2016 |
Igawa H, Stepanov V, Tari L, Okuda S, Yamamoto S, Kasai S, Nagisa Y, Häggkvist J, Svedberg M, Tóth M, Takano A, Halldin C. Development of a Novel Carbon-11 Labeled PET Radioligand for Melanin-Concentrating Hormone Receptor 1. Current Radiopharmaceuticals. PMID 28034352 DOI: 10.2174/1874471009666161230113630 |
0.429 |
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| 2016 |
Jucaite A, Cselényi Z, Lappalainen J, McCarthy DJ, Lee CM, Nyberg S, Varnäs K, Stenkrona P, Halldin C, Cross A, Farde L. GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans. Psychopharmacology. PMID 28013354 DOI: 10.1007/S00213-016-4506-4 |
0.34 |
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| 2016 |
Stepanov V, Svedberg M, Jia Z, Krasikova R, Lemoine L, Okamura N, Furumoto S, Mitsios N, Mulder J, Långström B, Nordberg A, Halldin C. Development of [(11)C]/[(3)H]THK-5351 - A potential novel carbon-11 tau imaging PET radioligand. Nuclear Medicine and Biology. 46: 50-53. PMID 28013122 DOI: 10.1016/J.Nucmedbio.2016.12.004 |
0.379 |
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| 2016 |
Häggkvist J, Tóth M, Tari L, Varnäs K, Svedberg M, Forsberg A, Nag S, Dominguez C, Munoz-Sanjuan I, Bard J, Wityak J, Varrone A, Halldin C, Mrzljak L. Longitudinal microPET imaging of the zQ175 mouse model of Huntington's disease shows in vivo changes of molecular targets in the striatum and the cerebral cortex. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27856625 DOI: 10.2967/Jnumed.116.180497 |
0.343 |
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| 2016 |
Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Nielsen J, Bundgaard C, Bang-Andersen B, Grimwood S, Halldin C, Farde L, Finnema SJ. Characterization of [(11)C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27817159 DOI: 10.1007/S00259-016-3544-9 |
0.49 |
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| 2016 |
Kuang G, Wang X, Halldin C, Nordberg A, Långström B, Ågren H, Tu Y. Theoretical study of the binding profile of an allosteric modulator NS-1738 with a chimera structure of the α7 nicotinic acetylcholine receptor. Physical Chemistry Chemical Physics : Pccp. PMID 27711412 DOI: 10.1039/C6Cp02278B |
0.302 |
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| 2016 |
Sturm S, Forsberg A, Nave S, Stenkrona P, Seneca N, Varrone A, Comley RA, Fazio P, Jamois C, Nakao R, Ejduk Z, Al-Tawil N, Akenine U, Halldin C, Andreasen N, et al. Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27633250 DOI: 10.1007/S00259-016-3510-6 |
0.31 |
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| 2016 |
Takano A, Varrone A, Gulyás B, Salvadori P, Gee A, Windhorst A, Vercouillie J, Bormans G, Lammertsma AA, Halldin C. Guidelines to PET measurements of the target occupancy in the brain for drug development. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27514528 DOI: 10.1007/S00259-016-3476-4 |
0.538 |
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| 2016 |
Veldman ER, Jia Z, Halldin C, Svedberg MM. Amyloid binding properties of curcumin analogues in Alzheimeŕs disease postmortem brain tissue. Neuroscience Letters. PMID 27461789 DOI: 10.1016/J.Neulet.2016.07.045 |
0.336 |
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| 2016 |
Takano A, Stenkrona P, Stepanov V, Amini N, Martinsson S, Tsai M, Goldsmith P, Xie J, Wu J, Uz T, Halldin C, Macek TA. A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor. Neuroimage. PMID 27423256 DOI: 10.1016/J.Neuroimage.2016.06.047 |
0.491 |
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| 2016 |
Varnas K, Jureus A, Johnstrom P, Ahlgren C, Schott P, Schou M, Gruber S, Jerning E, Malmborg J, Halldin C, Afzelius L, Farde L. Integrated strategy for use of PET in non-human primate to confirm multi-target occupancy of novel psychotropic drugs: an example with AZD3676. The Journal of Pharmacology and Experimental Therapeutics. PMID 27402278 DOI: 10.1124/Jpet.116.234146 |
0.463 |
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| 2016 |
Tiger M, Farde L, Rück C, Varrone A, Forsberg A, Lindefors N, Halldin C, Lundberg J. Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder. Psychiatry Research. 253: 36-42. PMID 27269199 DOI: 10.1016/J.Pscychresns.2016.04.016 |
0.439 |
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| 2016 |
Sonni I, Fazio P, Schain M, Halldin C, Svenningsson P, Farde L, Varrone A. Optimal acquisition time window and simplified quantification of dopamine transporter availability using 18F-FE-PE2I in healthy controls and Parkinson's disease patients. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27230923 DOI: 10.2967/Jnumed.115.171231 |
0.361 |
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| 2016 |
Fazio P, Schain M, Varnäs K, Halldin C, Farde L, Varrone A. Mapping the distribution of serotonin transporter in the human brainstem with high resolution PET: Validation using post-mortem autoradiography data. Neuroimage. PMID 26994829 DOI: 10.1016/J.Neuroimage.2016.03.019 |
0.407 |
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| 2016 |
Varnäs K, Finnema SJ, Stepanov V, Takano A, Tóth M, Svedberg M, Nielsen SM, Khanzhin NA, Juhl K, Bang-Andersen B, Halldin C, Farde L. Neurokinin-3 receptor binding in guinea pig, monkey and human brain: In vitro and in vivo imaging using the novel radioligand, [18F]Lu AF10628. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26993630 DOI: 10.1093/Ijnp/Pyw023 |
0.426 |
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| 2016 |
Takano A, Stepanov V, Nakao R, Amini N, Gulyás B, Kimura H, Halldin C. Brain PET measurement of PDE10A occupancy by TAK-063, a new PDE10A inhibitor, using [(11) C]T-773 in nonhuman primates. Synapse (New York, N.Y.). PMID 26878349 DOI: 10.1002/Syn.21896 |
0.624 |
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| 2016 |
Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, Lekander M, Höglund CO, Kosek E, Lampa J, Halldin C, Farde L, Varrone A, Cervenka S. In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects. Brain, Behavior, and Immunity. PMID 26820224 DOI: 10.1016/J.Bbi.2016.01.019 |
0.396 |
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| 2016 |
Dahl K, Schou M, Halldin C. Direct and Efficient (Carbonyl)cobalt-Mediated Aryl Acetylation Using [11C]Methyl Iodide European Journal of Organic Chemistry. 2016: 2775-2777. DOI: 10.1002/Ejoc.201600085 |
0.313 |
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| 2015 |
Yang CT, Tao H, Jackson AW, Chandrasekharan P, Padmanabhan P, Gulyás B, Halldin C. Biocompatible branched copolymer nanoparticles prepared by RAFT polymerization as MRI/PET bimodal tracers. Ejnmmi Physics. 2: A90. PMID 26956353 DOI: 10.1186/2197-7364-2-S1-A90 |
0.49 |
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| 2015 |
Borg J, Cervenka S, Kuja-Halkola R, Matheson GJ, Jönsson EG, Lichtenstein P, Henningsson S, Ichimiya T, Larsson H, Stenkrona P, Halldin C, Farde L. Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain. Molecular Psychiatry. PMID 26821979 DOI: 10.1038/Mp.2015.147 |
0.468 |
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| 2015 |
Nag S, Fazio P, Lehmann L, Kettschau G, Heinrich T, Thiele A, Svedberg M, Amini N, Leesch S, Catafau A, Hannestad J, Varrone A, Halldin C. In Vivo/In Vitro Characterisation of a Novel MAO-B Inhibitor Radioligand, Fluorine-18 Labeled Deuterated Fluorodeprenyl (18F-Fluorodeprenyl-D2). Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26585057 DOI: 10.2967/Jnumed.115.161083 |
0.333 |
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| 2015 |
Gourand F, Amini N, Jia Z, Stone-Elander S, Guilloteau D, Barré L, Halldin C. [11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET). Plos One. 10: e0137160. PMID 26367261 DOI: 10.1371/Journal.Pone.0137160 |
0.437 |
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| 2015 |
Collste K, Forsberg A, Varrone A, Amini N, Aeinehband S, Yakushev I, Halldin C, Farde L, Cervenka S. Test-retest reproducibility of [(11)C]PBR28 binding to TSPO in healthy control subjects. European Journal of Nuclear Medicine and Molecular Imaging. PMID 26293827 DOI: 10.1007/S00259-015-3149-8 |
0.428 |
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| 2015 |
Rahman O, Takano A, Amini N, Dahl K, Kanegawa N, Långström B, Farde L, Halldin C. Synthesis of ([(11)C]carbonyl)raclopride and a comparison with ([(11)C]methyl)raclopride in a monkey PET study. Nuclear Medicine and Biology. 42: 893-8. PMID 26272268 DOI: 10.1016/J.Nucmedbio.2015.07.003 |
0.477 |
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| 2015 |
Jucaite A, Svenningsson P, Rinne JO, Cselényi Z, Varnäs K, Johnström P, Amini N, Kirjavainen A, Helin S, Minkwitz M, Kugler AR, Posener JA, Budd S, Halldin C, Varrone A, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain : a Journal of Neurology. 138: 2687-700. PMID 26137956 DOI: 10.1093/Brain/Awv184 |
0.372 |
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| 2015 |
Mattsson P, Forsberg A, Persson J, Nyberg L, Nilsson LG, Halldin C, Farde L. β-Amyloid binding in elderly subjects with declining or stable episodic memory function measured with PET and [(11)C]AZD2184. European Journal of Nuclear Medicine and Molecular Imaging. PMID 26115835 DOI: 10.1007/S00259-015-3103-9 |
0.365 |
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| 2015 |
Tóth M, Doorduin J, Häggkvist J, Varrone A, Amini N, Halldin C, Gulyás B. Positron Emission Tomography studies with [11C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation. Plos One. 10: e0125917. PMID 25996996 DOI: 10.1371/Journal.Pone.0125917 |
0.628 |
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| 2015 |
Finnema SJ, Halldin C, Bang-Andersen B, Bundgaard C, Farde L. Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [(11)C]MADAM PET study. Psychopharmacology. 232: 4159-67. PMID 25980484 DOI: 10.1007/S00213-015-3961-7 |
0.494 |
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| 2015 |
Finnema SJ, Scheinin M, Shahid M, Lehto J, Borroni E, Bang-Andersen B, Sallinen J, Wong E, Farde L, Halldin C, Grimwood S. Application of cross-species PET imaging to assess neurotransmitter release in brain. Psychopharmacology. PMID 25921033 DOI: 10.1007/S00213-015-3938-6 |
0.46 |
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| 2015 |
Varrone A, Svenningsson P, Marklund P, Fatouros-Bergman H, Forsberg A, Halldin C, Nilsson LG, Farde L. 5-HT1B receptor imaging and cognition: a positron emission tomography study in control subjects and Parkinson's disease patients. Synapse (New York, N.Y.). 69: 365-74. PMID 25914348 DOI: 10.1002/Syn.21823 |
0.337 |
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| 2015 |
Rodriguez-Vieitez E, Ni R, Gulyás B, Tóth M, Häggkvist J, Halldin C, Voytenko L, Marutle A, Nordberg A. Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study. European Journal of Nuclear Medicine and Molecular Imaging. 42: 1119-32. PMID 25893384 DOI: 10.1007/S00259-015-3047-0 |
0.587 |
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| 2015 |
Takano A, Stepanov V, Gulyás B, Nakao R, Amini N, Miura S, Kimura H, Taniguchi T, Halldin C. Evaluation of a novel PDE10A PET radioligand, [(11) C]T-773, in nonhuman primates: Brain and whole body PET and brain autoradiography. Synapse (New York, N.Y.). 69: 345-55. PMID 25892433 DOI: 10.1002/Syn.21821 |
0.653 |
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| 2015 |
Stepanov V, Miura S, Takano A, Amini N, Nakao R, Hasui T, Nakashima K, Taniguchi T, Kimura H, Kuroita T, Halldin C. Development of a series of novel carbon-11 labeled PDE10A inhibitors. Journal of Labelled Compounds & Radiopharmaceuticals. 58: 202-8. PMID 25891816 DOI: 10.1002/Jlcr.3284 |
0.444 |
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| 2015 |
Dahl K, Itsenko O, Rahman O, Ulin J, Sjöberg CO, Sandblom P, Larsson LA, Schou M, Halldin C. An evaluation of a high-pressure (11)CO carbonylation apparatus. Journal of Labelled Compounds & Radiopharmaceuticals. 58: 220-5. PMID 25820685 DOI: 10.1002/Jlcr.3280 |
0.35 |
|
| 2015 |
Schou M, Varnäs K, Lundquist S, Nakao R, Amini N, Takano A, Finnema SJ, Halldin C, Farde L. Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 25813017 DOI: 10.1093/Ijnp/Pyv036 |
0.339 |
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| 2015 |
Fazio P, Svenningsson P, Forsberg A, Jönsson EG, Amini N, Nakao R, Nag S, Halldin C, Farde L, Varrone A. Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 714-20. PMID 25791993 DOI: 10.2967/Jnumed.114.152421 |
0.346 |
|
| 2015 |
Hjorth S, Karlsson C, Jucaite A, Varnäs K, Wählby Hamrén U, Johnström P, Gulyás B, Donohue SR, Pike VW, Halldin C, Farde L. A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates. Neuropharmacology. PMID 25791528 DOI: 10.1016/J.Neuropharm.2015.03.002 |
0.617 |
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| 2015 |
Johnström P, Bergman L, Varnäs K, Malmquist J, Halldin C, Farde L. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nuclear Medicine and Biology. 42: 555-60. PMID 25726760 DOI: 10.1016/J.Nucmedbio.2015.02.001 |
0.409 |
|
| 2015 |
Paul G, Zachrisson O, Varrone A, Almqvist P, Jerling M, Lind G, Rehncrona S, Linderoth B, Bjartmarz H, Shafer LL, Coffey R, Svensson M, Mercer KJ, Forsberg A, Halldin C, et al. Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients. The Journal of Clinical Investigation. 125: 1339-46. PMID 25689258 DOI: 10.1172/Jci79635 |
0.309 |
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| 2015 |
Tóth M, Häggkvist J, Stepanov V, Takano A, Nakao R, Amini N, Miura S, Kimura H, Taniguchi T, Gulyás B, Halldin C. Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 445-9. PMID 25622810 DOI: 10.1007/S11307-015-0822-Z |
0.578 |
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| 2015 |
Tóth M, Little P, Arnberg F, Häggkvist J, Mulder J, Halldin C, Gulyás B, Holmin S. Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking. Brain Structure & Function. PMID 25601153 DOI: 10.1007/S00429-014-0970-Y |
0.549 |
|
| 2015 |
Lehto J, Hirvonen MM, Johansson J, Kemppainen J, Luoto P, Naukkarinen T, Oikonen V, Arponen E, Rouru J, Sallinen J, Scheinin H, Vuorilehto L, Finnema SJ, Halldin C, Rinne JO, et al. Validation of [(11) C]ORM-13070 as a PET tracer for alpha2c -adrenoceptors in the human brain. Synapse (New York, N.Y.). 69: 172-81. PMID 25530024 DOI: 10.1002/Syn.21798 |
0.499 |
|
| 2015 |
Finnema SJ, Hughes ZA, Haaparanta-Solin M, Stepanov V, Nakao R, Varnäs K, Varrone A, Arponen E, Marjamäki P, Pohjanoksa K, Vuorilehto L, Babalola PA, Solin O, Grimwood S, Sallinen J, ... ... Halldin C, et al. Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522417 DOI: 10.1093/Ijnp/Pyu081 |
0.483 |
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| 2015 |
Comley RA, van der Aart J, Gulyás B, Garnier M, Iavarone L, Halldin C, Rabiner EA. In vivo occupancy of the 5-HT1A receptor by a novel pan 5-HT1(A/B/D) receptor antagonist, GSK588045, using positron emission tomography. Neuropharmacology. 92: 44-8. PMID 25476970 DOI: 10.1016/J.Neuropharm.2014.11.017 |
0.601 |
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| 2015 |
Jovanovic H, Kocoska-Maras L, Rådestad AF, Halldin C, Borg J, Hirschberg AL, Nordström AL. Effects of estrogen and testosterone treatment on serotonin transporter binding in the brain of surgically postmenopausal women--a PET study. Neuroimage. 106: 47-54. PMID 25462800 DOI: 10.1016/J.Neuroimage.2014.11.003 |
0.38 |
|
| 2015 |
Harada A, Suzuki K, Miura S, Hasui T, Kamiguchi N, Ishii T, Taniguchi T, Kuroita T, Takano A, Stepanov V, Halldin C, Kimura H. Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A. Nuclear Medicine and Biology. 42: 146-54. PMID 25451212 DOI: 10.1016/J.Nucmedbio.2014.09.005 |
0.397 |
|
| 2015 |
Varrone A, Oikonen V, Forsberg A, Joutsa J, Takano A, Solin O, Haaparanta-Solin M, Nag S, Nakao R, Al-Tawil N, Wells LA, Rabiner EA, Valencia R, Schultze-Mosgau M, Thiele A, ... ... Halldin C, et al. Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects. European Journal of Nuclear Medicine and Molecular Imaging. 42: 438-46. PMID 25412766 DOI: 10.1007/S00259-014-2955-8 |
0.361 |
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| 2015 |
Tóth M, Doorduin J, Häggkvist J, Varrone A, Amini N, Halldin C, Gulyás B. Positron emission tomography studies with [11C]PBR28 in the healthy rodent brain: Validating SUV as an outcome measure of neuroinflammation Plos One. 10. DOI: 10.1371/journal.pone.0125917 |
0.549 |
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| 2015 |
Dahl K, Schou M, Ulin J, Sjöberg CO, Farde L, Halldin C. 11C-carbonylation reactions using gas-liquid segmented microfluidics Rsc Advances. 5: 88886-88889. DOI: 10.1039/C5Ra20646D |
0.346 |
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| 2015 |
Takano A, Stenkrona P, Stepanov V, Amini N, Martinsson S, Tsai M, Goldsmith P, Wu J, Xie J, Uz T, Macek T, Halldin C. P.1.i.028 Brain phosphodiesterase 10A occupancy measured by PET after oral administration of TAK-063, a newly developed phosphodiesterase 10A inhibitor, in human volunteers European Neuropsychopharmacology. 25: S316. DOI: 10.1016/S0924-977X(15)30387-4 |
0.336 |
|
| 2015 |
Takano A, Stepanov V, Stenkrona P, Amini N, Martinsson S, Tsai M, Goldsmith P, Wu J, Xie J, Uz T, Macek T, Halldin C. P.1.i.027 Quantitative analysis and test-retest reproducibility of a new phosphodiesterase 10A PET radioligand [11C]T-773 in human brain European Neuropsychopharmacology. 25: S315. DOI: 10.1016/S0924-977X(15)30386-2 |
0.409 |
|
| 2015 |
Takano A, Stepanov V, Nakao R, Amini N, Kimura H, Halldin C. P.1.i.025 Brain PET measurement of phosphodiesterase 10A occupancy by TAK-063, a new phosphodiesterase 10A inhibitor, using [11C]T-773 in nonhuman primates European Neuropsychopharmacology. 25: S313-S314. DOI: 10.1016/S0924-977X(15)30384-9 |
0.358 |
|
| 2015 |
Finnema SJ, Halldin C, Bang-Andersen B, Bundgaard C, Farde L. Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [11C]MADAM PET study Psychopharmacology. DOI: 10.1007/s00213-015-3961-7 |
0.367 |
|
| 2014 |
Tóth M, Häggkvist J, Varrone A, Finnema SJ, Doorduin J, Tokunaga M, Higuchi M, Gulyás B, Halldin C. ABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [ (11)C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig. Ejnmmi Research. 4: 64. PMID 26116125 DOI: 10.1186/S13550-014-0064-0 |
0.623 |
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| 2014 |
Braniste V, Al-Asmakh M, Kowal C, Anuar F, Abbaspour A, Tóth M, Korecka A, Bakocevic N, Ng LG, Guan NL, Kundu P, Gulyás B, Halldin C, Hultenby K, Nilsson H, et al. The gut microbiota influences blood-brain barrier permeability in mice. Science Translational Medicine. 6: 263ra158. PMID 25411471 DOI: 10.1126/Scitranslmed.3009759 |
0.509 |
|
| 2014 |
Todde S, Windhorst AD, Behe M, Bormans G, Decristoforo C, Faivre-Chauvet A, Ferrari V, Gee AD, Gulyas B, Halldin C, Peitl PK, Koziorowski J, Mindt TL, Sollini M, Vercouillie J, et al. EANM guideline for the preparation of an Investigational Medicinal Product Dossier (IMPD). European Journal of Nuclear Medicine and Molecular Imaging. 41: 2175-85. PMID 25081821 DOI: 10.1007/S00259-014-2866-8 |
0.465 |
|
| 2014 |
Tiger M, Svenningsson P, Nord M, Jabre S, Halldin C, Lundberg J. No correlation between serotonin and its metabolite 5-HIAA in the cerebrospinal fluid and [(11) C]AZ10419369 binding measured with PET in healthy volunteers. Synapse (New York, N.Y.). 68: 480-3. PMID 24988901 DOI: 10.1002/Syn.21761 |
0.456 |
|
| 2014 |
Gulyás B, Sovago J, Gomez-Mancilla B, Jia Z, Szigeti C, Gulya K, Schumacher M, Maguire RP, Gasparini F, Halldin C. Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease: a preliminary investigation in the postmortem human brain. Brain Structure & Function. PMID 24969128 DOI: 10.1007/S00429-014-0812-Y |
0.549 |
|
| 2014 |
Amini N, Nakao R, Schou M, Halldin C. Determination of plasma protein binding of positron emission tomography radioligands by high-performance frontal analysis. Journal of Pharmaceutical and Biomedical Analysis. 98: 140-3. PMID 24922085 DOI: 10.1016/J.Jpba.2014.05.024 |
0.443 |
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| 2014 |
Tiger M, Rück C, Forsberg A, Varrone A, Lindefors N, Halldin C, Farde L, Lundberg J. Reduced 5-HT(1B) receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder. Psychiatry Research. 223: 164-70. PMID 24916155 DOI: 10.1016/J.Pscychresns.2014.05.011 |
0.416 |
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| 2014 |
Schain M, Varnäs K, Cselényi Z, Halldin C, Farde L, Varrone A. Evaluation of two automated methods for PET region of interest analysis. Neuroinformatics. 12: 551-62. PMID 24880728 DOI: 10.1007/S12021-014-9233-6 |
0.386 |
|
| 2014 |
Gourand F, Emond P, Bergström JP, Takano A, Gulyás B, Guilloteau D, Barré L, Halldin C. A radiometabolite study of the serotonin transporter PET radioligand [(11)C]MADAM. Nuclear Medicine and Biology. 41: 501-6. PMID 24857865 DOI: 10.1016/J.Nucmedbio.2014.03.022 |
0.559 |
|
| 2014 |
Finnema SJ, Stepanov V, Nakao R, Sromek AW, Zhang T, Neumeyer JL, George SR, Seeman P, Stabin MG, Jonsson C, Farde L, Halldin C. (18)F-MCL-524, an (18)F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1164-70. PMID 24790219 DOI: 10.2967/Jnumed.113.133876 |
0.451 |
|
| 2014 |
Suzuki M, Ito H, Kodaka F, Takano H, Kimura Y, Fujiwara H, Sasaki T, Takahata K, Nogami T, Nagashima T, Nengaki N, Kawamura K, Zhang MR, Varrone A, Halldin C, et al. Reproducibility of PET measurement for presynaptic dopaminergic functions using L-[β-(11)C]DOPA and [(18)F]FE-PE2I in humans. Nuclear Medicine Communications. 35: 231-7. PMID 24468851 DOI: 10.1097/Mnm.0000000000000052 |
0.402 |
|
| 2014 |
Yamanaka H, Yokoyama C, Mizuma H, Kurai S, Finnema SJ, Halldin C, Doi H, Onoe H. A possible mechanism of the nucleus accumbens and ventral pallidum 5-HT1B receptors underlying the antidepressant action of ketamine: a PET study with macaques. Translational Psychiatry. 4: e342. PMID 24399045 DOI: 10.1038/Tp.2013.112 |
0.494 |
|
| 2014 |
Takano A, Gulyás B, Varnäs K, Little PB, Noerregaard PK, Jensen NO, Elling CE, Halldin C. Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: a PET study. Synapse (New York, N.Y.). 68: 89-97. PMID 24293119 DOI: 10.1002/Syn.21721 |
0.62 |
|
| 2014 |
Varrone A, Svenningsson P, Forsberg A, Varnäs K, Tiger M, Nakao R, Halldin C, Nilsson LG, Farde L. Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease. Neurobiology of Aging. 35: 867-75. PMID 24126162 DOI: 10.1016/J.Neurobiolaging.2013.08.025 |
0.342 |
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| 2014 |
Tsujikawa T, Zoghbi SS, Hong J, Donohue SR, Jenko KJ, Gladding RL, Halldin C, Pike VW, Innis RB, Fujita M. In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors. Neuroimage. 84: 733-41. PMID 24076222 DOI: 10.1016/J.Neuroimage.2013.09.043 |
0.539 |
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| 2014 |
Nord M, Finnema SJ, Schain M, Halldin C, Farde L. Test-retest reliability of [11C]AZ10419369 binding to 5-HT(1B) receptors in human brain. European Journal of Nuclear Medicine and Molecular Imaging. 41: 301-7. PMID 24006152 DOI: 10.1007/S00259-013-2529-1 |
0.49 |
|
| 2014 |
Schou M, Varnäs K, Sandell J, Johnström P, Cselenyi Z, Svensson S, Nakao R, Amini N, Bergman L, Sumic A, Gulyas B, Lindström-Böö E, Halldin C, Farde L. Synthesis, radiolabeling, and in vivo pharmacokinetic evaluation of the amyloid beta radioligand [11C]AZD4694 in nonhuman primates. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 173-9. PMID 24002613 DOI: 10.1007/S11307-013-0666-3 |
0.649 |
|
| 2014 |
Finnema SJ, Stepanov V, Ettrup A, Nakao R, Amini N, Svedberg M, Lehmann C, Hansen M, Knudsen GM, Halldin C. Characterization of [(11)C]Cimbi-36 as an agonist PET radioligand for the 5-HT(2A) and 5-HT(2C) receptors in the nonhuman primate brain. Neuroimage. 84: 342-53. PMID 23994452 DOI: 10.1016/J.Neuroimage.2013.08.035 |
0.524 |
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| 2014 |
Tóth M, Häggkvist J, Varrone A, Finnema SJ, Doorduin J, Tokunaga M, Higuchi M, Gulyás B, Halldin C. ABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [11C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig Ejnmmi Research. 4. DOI: 10.1186/s13550-014-0064-0 |
0.602 |
|
| 2014 |
Fazio P, Fitzer-Attas C, Mrzljak L, Martinsson S, Landwehrmeyer G, Bronzova J, Al-Tawil N, Halldin C, Sampaio C, Varrone A. E31 Positron Emission Tomography Imaging Of Phosphodiesterase 10 A Enzyme And Dopamine D2 Receptor In Huntington's Disease Gene Expansion Carriers Journal of Neurology, Neurosurgery & Psychiatry. 85: A47-A47. DOI: 10.1136/Jnnp-2014-309032.134 |
0.448 |
|
| 2013 |
Andersson JD, Halldin C. PET radioligands targeting the brain GABAA /benzodiazepine receptor complex. Journal of Labelled Compounds & Radiopharmaceuticals. 56: 196-206. PMID 24285326 DOI: 10.1002/Jlcr.3008 |
0.645 |
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| 2013 |
Nag S, Lehmann L, Kettschau G, Toth M, Heinrich T, Thiele A, Varrone A, Halldin C. Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B). Bioorganic & Medicinal Chemistry. 21: 6634-41. PMID 24012376 DOI: 10.1016/J.Bmc.2013.08.019 |
0.439 |
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| 2013 |
Nagy K, Tóth M, Major P, Patay G, Egri G, Häggkvist J, Varrone A, Farde L, Halldin C, Gulyás B. Performance evaluation of the small-animal nanoScan PET/MRI system. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1825-32. PMID 23990683 DOI: 10.2967/Jnumed.112.119065 |
0.533 |
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| 2013 |
Nakao R, Amini N, Halldin C. Simultaneous determination of protein-free and total positron emission tomography radioligand concentrations in plasma using high-performance frontal analysis followed by mixed micellar liquid chromatography: application to [11C]PBR28 in human plasma. Analytical Chemistry. 85: 8728-34. PMID 23978238 DOI: 10.1021/Ac401742V |
0.407 |
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| 2013 |
Airaksinen AJ, Finnema SJ, Balle T, Varnäs K, Bang-Andersen B, Gulyás B, Farde L, Halldin C. Radiosynthesis and evaluation of new α1-adrenoceptor antagonists as PET radioligands for brain imaging. Nuclear Medicine and Biology. 40: 747-54. PMID 23810488 DOI: 10.1016/J.Nucmedbio.2013.05.007 |
0.648 |
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| 2013 |
Nyberg S, Jucaite A, Takano A, Kågedal M, Cselényi Z, Halldin C, Farde L. Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2235-44. PMID 23809226 DOI: 10.1017/S1461145713000680 |
0.453 |
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| 2013 |
Nakao R, Halldin C. Improved radiometabolite analysis procedure for positron emission tomography (PET) radioligands using a monolithic column coupled with direct injection micellar/high submicellar liquid chromatography. Talanta. 113: 130-4. PMID 23708634 DOI: 10.1016/J.Talanta.2013.03.024 |
0.408 |
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| 2013 |
Kågedal M, Cselényi Z, Nyberg S, Raboisson P, Ståhle L, Stenkrona P, Varnäs K, Halldin C, Hooker AC, Karlsson MO. A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 - estimating occupancy in the absence of a reference region. Neuroimage. 82: 160-9. PMID 23668965 DOI: 10.1016/J.Neuroimage.2013.05.006 |
0.435 |
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| 2013 |
Takano A, Piehl F, Hillert J, Varrone A, Nag S, Gulyás B, Stenkrona P, Villemagne VL, Rowe CC, Macdonell R, Tawil NA, Kucinski T, Zimmermann T, Schultze-Mosgau M, Thiele A, ... ... Halldin C, et al. In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106. Ejnmmi Research. 3: 30. PMID 23618062 DOI: 10.1186/2191-219X-3-30 |
0.569 |
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| 2013 |
Nakao R, Halldin C. A simplified radiometabolite analysis procedure for PET radioligands using a solid phase extraction with micellar medium. Nuclear Medicine and Biology. 40: 658-63. PMID 23602762 DOI: 10.1016/J.Nucmedbio.2013.02.007 |
0.374 |
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| 2013 |
Kannan P, Pike VW, Halldin C, Langer O, Gottesman MM, Innis RB, Hall MD. Factors that limit positron emission tomography imaging of p-glycoprotein density at the blood-brain barrier. Molecular Pharmaceutics. 10: 2222-9. PMID 23597242 DOI: 10.1021/Mp400011G |
0.389 |
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| 2013 |
Schain M, Benjaminsson S, Varnäs K, Forsberg A, Halldin C, Lansner A, Farde L, Varrone A. Arterial input function derived from pairwise correlations between PET-image voxels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1058-65. PMID 23571279 DOI: 10.1038/Jcbfm.2013.47 |
0.372 |
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| 2013 |
Andersson JD, Seneca N, Truong P, Wensbo D, Raboisson P, Farde L, Halldin C. Palladium mediated ¹¹C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [¹¹C]AZD9272. Nuclear Medicine and Biology. 40: 547-53. PMID 23541825 DOI: 10.1016/J.Nucmedbio.2012.12.012 |
0.679 |
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| 2013 |
Finnema SJ, Bang-Andersen B, Jørgensen M, Christoffersen CT, Gulyás B, Wikström HV, Farde L, Halldin C. The dopamine D₠receptor agonist (S)-[¹¹C]N-methyl-NNC 01-0259 is not sensitive to changes in dopamine concentration--a positron emission tomography examination in the monkey brain. Synapse (New York, N.Y.). 67: 586-95. PMID 23504964 DOI: 10.1002/syn.21664 |
0.582 |
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| 2013 |
Varrone A, Mattsson P, Forsberg A, Takano A, Nag S, Gulyás B, Borg J, Boellaard R, Al-Tawil N, Eriksdotter M, Zimmermann T, Schultze-Mosgau M, Thiele A, Hoffmann A, Lammertsma AA, ... Halldin C, et al. In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients. European Journal of Nuclear Medicine and Molecular Imaging. 40: 921-31. PMID 23436070 DOI: 10.1007/S00259-013-2359-1 |
0.59 |
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| 2013 |
Varnäs K, JuÄaite A, McCarthy DJ, Stenkrona P, Nord M, Halldin C, Farde L, Kanes S. A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers. Cephalalgia : An International Journal of Headache. 33: 853-60. PMID 23430984 DOI: 10.1177/0333102413476372 |
0.462 |
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| 2013 |
Stenkrona P, Halldin C, Lundberg J. 5-HTT and 5-HT(1A) receptor occupancy of the novel substance vortioxetine (Lu AA21004). A PET study in control subjects. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 1190-8. PMID 23428337 DOI: 10.1016/J.Euroneuro.2013.01.002 |
0.392 |
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| 2013 |
Nakao R, Halldin C. "Mixed" anionic and non-ionic micellar liquid chromatography for high-speed radiometabolite analysis of positron emission tomography radioligands. Journal of Chromatography. A. 1281: 54-9. PMID 23399000 DOI: 10.1016/J.Chroma.2013.01.071 |
0.351 |
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| 2013 |
Schou M, Varnäs K, Jucaite A, Gulyás B, Halldin C, Farde L. Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate. Nuclear Medicine and Biology. 40: 410-4. PMID 23352602 DOI: 10.1016/J.Nucmedbio.2012.10.011 |
0.654 |
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| 2013 |
Nord M, Finnema SJ, Halldin C, Farde L. Effect of a single dose of escitalopram on serotonin concentration in the non-human and human primate brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1577-86. PMID 23351590 DOI: 10.1017/S1461145712001617 |
0.356 |
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| 2013 |
Forsberg A, Juréus A, Cselényi Z, Eriksdotter M, Freund-Levi Y, Jeppsson F, Swahn BM, Sandell J, Julin P, Schou M, Andersson J, Johnström P, Varnäs K, Halldin C, Farde L, et al. Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients. European Journal of Nuclear Medicine and Molecular Imaging. 40: 580-93. PMID 23324871 DOI: 10.1007/S00259-012-2322-6 |
0.642 |
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| 2013 |
Máthé D, Horváth I, Szigeti K, Donohue SR, Pike VW, Jia Z, Ledent C, Palkovits M, Freund TF, Halldin C, Gulyás B. In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse. Brain Research Bulletin. 91: 46-51. PMID 23318272 DOI: 10.1016/J.Brainresbull.2013.01.001 |
0.591 |
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| 2013 |
Ikoma Y, Takano A, Varrone A, Halldin C. Graphic plot analysis for estimating binding potential of translocator protein (TSPO) in positron emission tomography studies with [¹â¸F]FEDAA1106. Neuroimage. 69: 78-86. PMID 23247191 DOI: 10.1016/J.Neuroimage.2012.12.009 |
0.313 |
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| 2013 |
Tóth M, Varrone A, Steiger C, Laszlovszky I, Horváth A, Kiss B, Gyertyán I, Adham N, Halldin C, Gulyás B. Brain uptake and distribution of the dopamine D3 /D2 receptor partial agonist [11 C]cariprazine: an in vivo positron emission tomography study in nonhuman primates. Synapse (New York, N.Y.). 67: 258-64. PMID 23238770 DOI: 10.1002/Syn.21631 |
0.648 |
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| 2013 |
Kodaka F, Ito H, Kimura Y, Fujie S, Takano H, Fujiwara H, Sasaki T, Nakayama K, Halldin C, Farde L, Suhara T. Test-retest reproducibility of dopamine D2/3 receptor binding in human brain measured by PET with [11C]MNPA and [11C]raclopride. European Journal of Nuclear Medicine and Molecular Imaging. 40: 574-9. PMID 23238524 DOI: 10.1007/S00259-012-2312-8 |
0.447 |
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| 2013 |
Jucaite A, Takano A, Boström E, Jostell KG, Stenkrona P, Halldin C, Segerdahl M, Nyberg S. AZD5213: a novel histamine H3 receptor antagonist permitting high daytime and low nocturnal H3 receptor occupancy, a PET study in human subjects. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1231-9. PMID 23217964 DOI: 10.1017/S1461145712001411 |
0.367 |
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| 2013 |
Nag S, Kettschau G, Heinrich T, Varrone A, Lehmann L, Gulyas B, Thiele A, Keller É, Halldin C. Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity. Bioorganic & Medicinal Chemistry. 21: 186-95. PMID 23211968 DOI: 10.1016/J.Bmc.2012.10.050 |
0.554 |
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| 2013 |
Amini N, Nakao R, Schou M, Halldin C. Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28. Analytical and Bioanalytical Chemistry. 405: 1303-10. PMID 23180082 DOI: 10.1007/S00216-012-6541-2 |
0.405 |
|
| 2013 |
Takano A, Halldin C, Farde L. SERT and NET occupancy by venlafaxine and milnacipran in nonhuman primates: a PET study. Psychopharmacology. 226: 147-53. PMID 23090625 DOI: 10.1007/S00213-012-2901-Z |
0.412 |
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| 2013 |
Schain M, Tóth M, Cselényi Z, Arakawa R, Halldin C, Farde L, Varrone A. Improved mapping and quantification of serotonin transporter availability in the human brainstem with the HRRT. European Journal of Nuclear Medicine and Molecular Imaging. 40: 228-37. PMID 23076621 DOI: 10.1007/S00259-012-2260-3 |
0.446 |
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| 2013 |
Guterstam J, Jayaram-Lindström N, Cervenka S, Frost JJ, Farde L, Halldin C, Franck J. Effects of amphetamine on the human brain opioid system--a positron emission tomography study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 763-9. PMID 22932428 DOI: 10.1017/S1461145712000818 |
0.404 |
|
| 2013 |
Ricci B, Sturm S, Seneca N, Jamois C, Nave S, Ejduk Z, Skenkrona P, Varonne A, Forsberg A, Fazio P, Halldin C, Al-Tawil N, Akenine U, Andreasen N. Brain MAO-B inhibition in healthy elderly and people with Alzheimer's disease after oral administration of RO4602522 Alzheimers & Dementia. 9: 667. DOI: 10.1016/J.Jalz.2013.05.1374 |
0.3 |
|
| 2013 |
Scheinin M, Hirvonen MM, Johansson J, Kemppainen J, Lehto J, Lovro Z, Luoto P, Oikonen V, Naukkarinen T, Rouru J, Sallinen J, Scheinin H, Vuorilehto L, Finnema SJ, Halldin C, et al. Evaluation of [11C]ORM-13070 as a PET tracer for α2C-adrenoceptors in the human brain Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 162. DOI: 10.1016/B978-0-12-800044-1.00145-8 |
0.376 |
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| 2013 |
Dahl K, Schou M, Amini N, Halldin C. Palladium-mediated [11C]carbonylation at atmospheric pressure: A general method using xantphos as supporting ligand European Journal of Organic Chemistry. 1228-1231. DOI: 10.1002/Ejoc.201201708 |
0.332 |
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| 2012 |
Nakao R, Schou M, Halldin C. Rapid metabolite analysis of positron emission tomography radioligands by direct plasma injection combining micellar cleanup with high submicellar liquid chromatography with radiometric detection. Journal of Chromatography. A. 1266: 76-83. PMID 23116800 DOI: 10.1016/J.Chroma.2012.10.022 |
0.352 |
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| 2012 |
Brockschnieder D, Schmitt-Willich H, Heinrich T, Varrone A, Gulyás B, Toth M, Andersson J, Boemer U, Krause S, Friebe M, Dinkelborg L, Halldin C, Dyrks T. Preclinical characterization of a novel class of 18F-labeled PET tracers for amyloid-β. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1794-801. PMID 23008501 DOI: 10.2967/Jnumed.112.104810 |
0.72 |
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| 2012 |
Funke SA, Bartnik D, Glück JM, Piorkowska K, Wiesehan K, Weber U, Gulyas B, Halldin C, Pfeifer A, Spenger C, Muhs A, Willbold D. Development of a small D-enantiomeric Alzheimer's amyloid-β binding peptide ligand for future in vivo imaging applications. Plos One. 7: e41457. PMID 22848501 DOI: 10.1371/Journal.Pone.0041457 |
0.527 |
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| 2012 |
Gulyás B, Tóth M, Schain M, Airaksinen A, Vas A, Kostulas K, Lindström P, Hillert J, Halldin C. Evolution of microglial activation in ischaemic core and peri-infarct regions after stroke: a PET study with the TSPO molecular imaging biomarker [((11))C]vinpocetine. Journal of the Neurological Sciences. 320: 110-7. PMID 22841414 DOI: 10.1016/J.Jns.2012.06.026 |
0.509 |
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| 2012 |
Cervenka S, Hedman E, Ikoma Y, Djurfeldt DR, Rück C, Halldin C, Lindefors N. Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder. Translational Psychiatry. 2: e120. PMID 22832965 DOI: 10.1038/Tp.2012.40 |
0.405 |
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| 2012 |
Fuchigami T, Takano A, Gulyás B, Jia Z, Finnema SJ, Andersson JD, Nakao R, Magata Y, Haratake M, Nakayama M, Halldin C. Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11 C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11 C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1. Ejnmmi Research. 2: 37. PMID 22776065 DOI: 10.1186/2191-219X-2-37 |
0.729 |
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| 2012 |
Sasaki T, Ito H, Kimura Y, Arakawa R, Takano H, Seki C, Kodaka F, Fujie S, Takahata K, Nogami T, Suzuki M, Fujiwara H, Takahashi H, Nakao R, Fukumura T, ... ... Halldin C, et al. Quantification of dopamine transporter in human brain using PET with 18F-FE-PE2I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1065-73. PMID 22689927 DOI: 10.2967/Jnumed.111.101626 |
0.423 |
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| 2012 |
Gulyás B, Halldin C. New PET radiopharmaceuticals beyond FDG for brain tumor imaging. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology. 56: 173-90. PMID 22617239 |
0.555 |
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| 2012 |
Ju?aite A, Cselényi Z, Arvidsson A, Ahlberg G, Julin P, Varnäs K, Stenkrona P, Andersson J, Halldin C, Farde L. Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects. Ejnmmi Research. 2: 15. PMID 22524272 DOI: 10.1186/2191-219X-2-15 |
0.632 |
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| 2012 |
Nakao R, Schou M, Halldin C. Rapid and sensitive measurement of PET radioligands in plasma by fast liquid chromatography/radiometric detection. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 895: 116-22. PMID 22494928 DOI: 10.1016/J.Jchromb.2012.03.028 |
0.389 |
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| 2012 |
Farkas S, Nagy K, Jia Z, Hortobágyi T, Varrone A, Halldin C, Csiba L, Gulyás B. Signal transduction pathway activity compensates dopamine Dâ‚‚/D₃ receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [³H]raclopride and [³âµS]GTPγS. Brain Research. 1453: 56-63. PMID 22480734 DOI: 10.1016/J.Brainres.2012.03.014 |
0.586 |
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| 2012 |
Nag S, Lehmann L, Kettschau G, Heinrich T, Thiele A, Varrone A, Gulyas B, Halldin C. Synthesis and evaluation of [¹â¸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B). Bioorganic & Medicinal Chemistry. 20: 3065-71. PMID 22436387 DOI: 10.1016/J.Bmc.2012.02.056 |
0.564 |
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| 2012 |
Farkas S, Nagy K, Jia Z, Harkany T, Palkovits M, Donohou SR, Pike VW, Halldin C, Máthé D, Csiba L, Gulyás B. The decrease of dopamine Dâ‚‚/D₃ receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CBâ‚ cannabinoid receptors in Parkinson's disease: a preliminary autoradiographic study with the selective dopamine Dâ‚‚/D₃ antagonist [³H]raclopride and the novel CBâ‚ inverse agonist [¹²âµI]SD7015. Brain Research Bulletin. 87: 504-10. PMID 22421165 DOI: 10.1016/J.Brainresbull.2012.02.012 |
0.546 |
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| 2012 |
Nakao R, Schou M, Halldin C. Direct plasma metabolite analysis of positron emission tomography radioligands by micellar liquid chromatography with radiometric detection. Analytical Chemistry. 84: 3222-30. PMID 22409870 DOI: 10.1021/Ac2032657 |
0.366 |
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| 2012 |
Cselényi Z, Jönhagen ME, Forsberg A, Halldin C, Julin P, Schou M, Johnström P, Varnäs K, Svensson S, Farde L. Clinical validation of 18F-AZD4694, an amyloid-β-specific PET radioligand. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 415-24. PMID 22323782 DOI: 10.2967/Jnumed.111.094029 |
0.436 |
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| 2012 |
Lundberg J, Tiger M, Landén M, Halldin C, Farde L. Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1167-72. PMID 22243688 DOI: 10.1017/S1461145711001945 |
0.364 |
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| 2012 |
Schain M, Tóth M, Cselényi Z, Stenkrona P, Halldin C, Farde L, Varrone A. Quantification of serotonin transporter availability with [11C]MADAM--a comparison between the ECAT HRRT and HR systems. Neuroimage. 60: 800-7. PMID 22227138 DOI: 10.1016/J.Neuroimage.2011.12.047 |
0.365 |
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| 2012 |
Farkas S, Nagy K, Palkovits M, Kovács GG, Jia Z, Donohue S, Pike V, Halldin C, Máthé D, Harkany T, Gulyás B, Csiba L. [¹²âµI]SD-7015 reveals fine modalities of CBâ‚ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease. Neurochemistry International. 60: 286-91. PMID 22222721 DOI: 10.1016/J.Neuint.2011.11.004 |
0.527 |
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| 2012 |
Finnema SJ, Varrone A, Hwang TJ, Halldin C, Farde L. Confirmation of fenfluramine effect on 5-HT(1B) receptor binding of [(11)C]AZ10419369 using an equilibrium approach. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 685-95. PMID 22167236 DOI: 10.1038/Jcbfm.2011.172 |
0.495 |
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| 2012 |
Jahan M, Nag S, Krasikova R, Weber U, Muhs A, Pfeifer A, Spenger C, Willbold D, Gulyás B, Halldin C. Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[18F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography. Nuclear Medicine and Biology. 39: 315-23. PMID 22136889 DOI: 10.1016/J.Nucmedbio.2011.09.008 |
0.594 |
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| 2012 |
Nag S, Varrone A, Tóth M, Thiele A, Kettschau G, Heinrich T, Lehmann L, Halldin C. In vivo evaluation in cynomolgus monkey brain and metabolism of [¹â¸F]fluorodeprenyl: a new MAO-B pet radioligand. Synapse (New York, N.Y.). 66: 323-30. PMID 22124971 DOI: 10.1002/Syn.21514 |
0.437 |
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| 2012 |
Gulyás B, Spenger C, Beliczai Z, Gulya K, Kása P, Jahan M, Jia Z, Weber U, Pfeifer A, Muhs A, Willbold D, Halldin C. Distribution and binding of 18F-labeled and 125I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: a whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer's disease patients. Neurochemistry International. 60: 153-62. PMID 22100791 DOI: 10.1016/J.Neuint.2011.10.010 |
0.615 |
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| 2012 |
Gulyas B, Toth M, Vas A, Shchukin E, Kostulas K, Hillert J, Halldin C. Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine. Current Radiopharmaceuticals. 5: 19-28. PMID 22074478 DOI: 10.2174/1874471011205010019 |
0.616 |
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| 2012 |
Odano I, Varrone A, Savic I, Ciumas C, Karlsson P, Jucaite A, Halldin C, Farde L. Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy. Neuroimage. 59: 3582-93. PMID 22056530 DOI: 10.1016/J.Neuroimage.2011.10.067 |
0.461 |
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| 2012 |
Varrone A, Gulyás B, Takano A, Stabin MG, Jonsson C, Halldin C. Simplified quantification and whole-body distribution of [18F]FE-PE2I in nonhuman primates: prediction for human studies. Nuclear Medicine and Biology. 39: 295-303. PMID 22033024 DOI: 10.1016/J.Nucmedbio.2011.08.004 |
0.542 |
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| 2012 |
Sestini S, Halldin C, Mansi L, Castagnoli A, Farde L. Pharmacokinetic analysis of plasma curves obtained after i.v. injection of the PET radioligand [11C] raclopride provides a likely explanation for rapid radioligand metabolism. Journal of Cellular Physiology. 227: 1663-9. PMID 21678422 DOI: 10.1002/Jcp.22890 |
0.432 |
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| 2012 |
Comley RA, Cervenka S, Palhagen SE, Panagiotidis G, Matthews JC, Lai RY, Halldin C, Farde L, Nichols TE, Whitcher BJ. A comparison of gray matter density in restless legs syndrome patients and matched controls using voxel-based morphometry. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 22: 28-32. PMID 21091816 DOI: 10.1111/J.1552-6569.2010.00536.X |
0.316 |
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| 2012 |
Guterstam J, Jayaram-Lindstrom N, Cervenka S, Halldin C, Farde L, Frost J, Franck J. P.3.004 Amphetamine-opioid interactions in the human brain reward system – a PET study using [11C]carfentanil European Neuropsychopharmacology. 22: S55. DOI: 10.1016/S0924-977X(12)70057-3 |
0.409 |
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| 2012 |
Schou M, Halldin C. Radiolabeling of two 11C-labeled formylating agents and their application in the preparation of [11C]benzimidazole Journal of Labelled Compounds and Radiopharmaceuticals. 55: 460-462. DOI: 10.1002/Jlcr.2972 |
0.331 |
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| 2012 |
Dahl K, Schou M, Halldin C. Radiofluorination and reductive amination using a microfluidic device Journal of Labelled Compounds and Radiopharmaceuticals. 55: 455-459. DOI: 10.1002/Jlcr.2970 |
0.302 |
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| 2012 |
Stepanov V, Krasikova R, Raus L, Loog O, Hiltunen J, Halldin C. An efficient one-step radiosynthesis of [ 18F]FE-PE2I, a PET radioligand for imaging of dopamine transporters Journal of Labelled Compounds and Radiopharmaceuticals. 55: 206-210. DOI: 10.1002/Jlcr.2927 |
0.353 |
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| 2011 |
Jahan M, Eriksson O, Johnström P, Korsgren O, Sundin A, Johansson L, Halldin C. Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET. Ejnmmi Research. 1: 33. PMID 22214308 DOI: 10.1186/2191-219X-1-33 |
0.37 |
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| 2011 |
Nag S, Lehmann L, Heinrich T, Thiele A, Kettschau G, Nakao R, Gulyás B, Halldin C. Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B). Journal of Medicinal Chemistry. 54: 7023-9. PMID 21923198 DOI: 10.1021/Jm200710B |
0.609 |
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| 2011 |
Varrone A, Stepanov V, Nakao R, Tóth M, Gulyás B, Emond P, Deloye JB, Vercouillie J, Stabin MG, Jonsson C, Guilloteau D, Halldin C. Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1313-21. PMID 21764797 DOI: 10.2967/Jnumed.111.089953 |
0.605 |
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| 2011 |
Takano A, Gulyás B, Varrone A, Karlsson P, Sjoholm N, Larsson S, Jonsson C, Odh R, Sparks R, Al Tawil N, Hoffmann A, Zimmermann T, Thiele A, Halldin C. Biodistribution and radiation dosimetry of the 18 kDa translocator protein (TSPO) radioligand [18F]FEDAA1106: a human whole-body PET study. European Journal of Nuclear Medicine and Molecular Imaging. 38: 2058-65. PMID 21732107 DOI: 10.1007/S00259-011-1864-3 |
0.575 |
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| 2011 |
Seneca N, Finnema SJ, Laszlovszky I, Kiss B, Horváth A, Pásztor G, Kapás M, Gyertyán I, Farkas S, Innis RB, Halldin C, Gulyás B. Occupancy of dopamine Dâ‚‚ and D₃ and serotonin 5-HTâ‚A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology. 218: 579-87. PMID 21625907 DOI: 10.1007/S00213-011-2343-Z |
0.619 |
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| 2011 |
Nord M, Nyberg S, Brogren J, Jucaite A, Halldin C, Farde L. Comparison of Dâ‚‚ dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1357-66. PMID 21477416 DOI: 10.1017/S1461145711000514 |
0.402 |
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| 2011 |
Donohue SR, Dannals RF, Halldin C, Pike VW. N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors. Journal of Medicinal Chemistry. 54: 2961-70. PMID 21428406 DOI: 10.1021/Jm2000536 |
0.403 |
|
| 2011 |
Takano A, Nag S, Gulyás B, Halldin C, Farde L. NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo. Psychopharmacology. 216: 279-86. PMID 21336575 DOI: 10.1007/S00213-011-2212-9 |
0.606 |
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| 2011 |
Gulyás B, Vas A, Tóth M, Takano A, Varrone A, Cselényi Z, Schain M, Mattsson P, Halldin C. Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine. Neuroimage. 56: 1111-21. PMID 21320609 DOI: 10.1016/J.Neuroimage.2011.02.020 |
0.593 |
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| 2011 |
Andersson JD, Pierson ME, Finnema SJ, Gulyás B, Heys R, Elmore CS, Farde L, Halldin C. Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds. Nuclear Medicine and Biology. 38: 261-72. PMID 21315282 DOI: 10.1016/J.Nucmedbio.2010.08.006 |
0.743 |
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| 2011 |
Kannan P, Brimacombe KR, Kreisl WC, Liow JS, Zoghbi SS, Telu S, Zhang Y, Pike VW, Halldin C, Gottesman MM, Innis RB, Hall MD. Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET. Proceedings of the National Academy of Sciences of the United States of America. 108: 2593-8. PMID 21262843 DOI: 10.1073/Pnas.1014641108 |
0.377 |
|
| 2011 |
Varnäs K, Nyberg S, Karlsson P, Pierson ME, Kågedal M, Cselényi Z, McCarthy D, Xiao A, Zhang M, Halldin C, Farde L. Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369. Psychopharmacology. 213: 533-45. PMID 21234549 DOI: 10.1007/S00213-011-2165-Z |
0.47 |
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| 2011 |
Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 132-9. PMID 21189414 DOI: 10.2967/Jnumed.110.077651 |
0.57 |
|
| 2011 |
Gulyás B, Pavlova E, Kása P, Gulya K, Bakota L, Várszegi S, Keller E, Horváth MC, Nag S, Hermecz I, Magyar K, Halldin C. Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography. Neurochemistry International. 58: 60-8. PMID 21075154 DOI: 10.1016/J.Neuint.2010.10.013 |
0.615 |
|
| 2011 |
Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J. Extrastriatal dopamine D(2) receptor binding in Huntington's disease. Human Brain Mapping. 32: 1626-36. PMID 20886576 DOI: 10.1002/Hbm.21134 |
0.43 |
|
| 2011 |
Kodaka F, Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Okumura M, Otsuka T, Nakayama K, Halldin C, Farde L, Suhara T. Effect of risperidone on high-affinity state of dopamine D2 receptors: a PET study with agonist ligand [11C](R)-2-CH3O-N-n-propylnorapomorphine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 83-9. PMID 20860881 DOI: 10.1017/S1461145710001148 |
0.45 |
|
| 2011 |
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 113-23. PMID 20424633 DOI: 10.1038/Jcbfm.2010.55 |
0.651 |
|
| 2010 |
Varrone A, Halldin C. Molecular imaging of the dopamine transporter. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1331-4. PMID 20720060 DOI: 10.2967/Jnumed.109.065656 |
0.368 |
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| 2010 |
Andersson JD, Varnäs K, Cselényi Z, Gulyás B, Wensbo D, Finnema SJ, Swahn BM, Svensson S, Nyberg S, Farde L, Halldin C. Radiosynthesis of the candidate beta-amyloid radioligand [(11)C]AZD2184: Positron emission tomography examination and metabolite analysis in cynomolgus monkeys. Synapse (New York, N.Y.). 64: 733-41. PMID 20698029 DOI: 10.1002/Syn.20782 |
0.749 |
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| 2010 |
Finnema SJ, Bang-Andersen B, Wikström HV, Halldin C. Current state of agonist radioligands for imaging of brain dopamine D2/D3 receptors in vivo with positron emission tomography. Current Topics in Medicinal Chemistry. 10: 1477-98. PMID 20583987 DOI: 10.2174/156802610793176837 |
0.475 |
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| 2010 |
Hirvonen J, Terry GE, Halldin C, Pike VW, Innis RB. Approaches to quantify radioligands that wash out slowly from target organs. European Journal of Nuclear Medicine and Molecular Imaging. 37: 917-9. PMID 20358196 DOI: 10.1007/S00259-010-1426-0 |
0.482 |
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| 2010 |
Eriksson O, Jahan M, Johnström P, Korsgren O, Sundin A, Halldin C, Johansson L. In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass. Nuclear Medicine and Biology. 37: 357-63. PMID 20346875 DOI: 10.1016/J.Nucmedbio.2009.12.004 |
0.387 |
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| 2010 |
Skinbjerg M, Seneca N, Liow JS, Hong J, Weinshenker D, Pike VW, Halldin C, Sibley DR, Innis RB. Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding. Synapse (New York, N.Y.). 64: 699-703. PMID 20336622 DOI: 10.1002/Syn.20781 |
0.422 |
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| 2010 |
Terry GE, Hirvonen J, Liow JS, Seneca N, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Pike VW, Halldin C, Innis RB. Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging. 37: 1499-506. PMID 20333514 DOI: 10.1007/S00259-010-1411-7 |
0.508 |
|
| 2010 |
Sekine M, Arakawa R, Ito H, Okumura M, Sasaki T, Takahashi H, Takano H, Okubo Y, Halldin C, Suhara T. Norepinephrine transporter occupancy by antidepressant in human brain using positron emission tomography with (S,S)-[18F]FMeNER-D2. Psychopharmacology. 210: 331-6. PMID 20309528 DOI: 10.1007/S00213-010-1824-9 |
0.384 |
|
| 2010 |
Finnema SJ, Varrone A, Hwang TJ, Gulyás B, Pierson ME, Halldin C, Farde L. Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain. Synapse (New York, N.Y.). 64: 573-7. PMID 20222157 DOI: 10.1002/Syn.20780 |
0.612 |
|
| 2010 |
Kannan P, Brimacombe KR, Zoghbi SS, Liow JS, Morse C, Taku AK, Pike VW, Halldin C, Innis RB, Gottesman MM, Hall MD. N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 917-22. PMID 20212014 DOI: 10.1124/Dmd.109.031161 |
0.365 |
|
| 2010 |
Gulyás B, Brockschnieder D, Nag S, Pavlova E, Kása P, Beliczai Z, Légrádi A, Gulya K, Thiele A, Dyrks T, Halldin C. The norepinephrine transporter (NET) radioligand (S,S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer's disease: a post-mortem autoradiographic study. Neurochemistry International. 56: 789-98. PMID 20211213 DOI: 10.1016/J.Neuint.2010.03.001 |
0.598 |
|
| 2010 |
Cervenka S, Varrone A, Fransén E, Halldin C, Farde L. PET studies of D2-receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans. Synapse (New York, N.Y.). 64: 478-85. PMID 20175222 DOI: 10.1002/Syn.20765 |
0.486 |
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| 2010 |
Jucaite A, Forssberg H, Karlsson P, Halldin C, Farde L. Age-related reduction in dopamine D1 receptors in the human brain: from late childhood to adulthood, a positron emission tomography study. Neuroscience. 167: 104-10. PMID 20109534 DOI: 10.1016/J.Neuroscience.2010.01.034 |
0.451 |
|
| 2010 |
Skinbjerg M, Liow JS, Seneca N, Hong J, Lu S, Thorsell A, Heilig M, Pike VW, Halldin C, Sibley DR, Innis RB. D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model. Neuroimage. 50: 1402-7. PMID 20097293 DOI: 10.1016/J.Neuroimage.2010.01.055 |
0.457 |
|
| 2010 |
NÃ¥gren K, Halldin C, Rinne JO. Radiopharmaceuticals for positron emission tomography investigations of Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 37: 1575-93. PMID 20033156 DOI: 10.1007/S00259-009-1301-Z |
0.385 |
|
| 2010 |
Terry GE, Hirvonen J, Liow JS, Zoghbi SS, Gladding R, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Donohue SR, Pike VW, Halldin C, Innis RB. Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 112-20. PMID 20008988 DOI: 10.2967/Jnumed.109.067074 |
0.49 |
|
| 2010 |
Cervenka S, Gustavsson JP, Halldin C, Farde L. Association between striatal and extrastriatal dopamine D2-receptor binding and social desirability. Neuroimage. 50: 323-8. PMID 20004254 DOI: 10.1016/J.Neuroimage.2009.12.006 |
0.403 |
|
| 2010 |
Finnema S, Varrone A, Hwang T, Farde L, Halldin C. P.1.e.021 In vivo assessment of changes in serotonin release in the non-human primate brain using PET and [11C]AZ10419369 European Neuropsychopharmacology. 20: S299-S300. DOI: 10.1016/S0924-977X(10)70399-0 |
0.424 |
|
| 2010 |
Jayaram-Lindström N, Haggkvist J, Halldin C, Schilström B, Nordström AL, Franck J. P.3.009 Effects of naltrexone on amphetamine-induced changes in the brain dopamine system European Neuropsychopharmacology. 20. DOI: 10.1016/S0924-977X(10)70081-X |
0.328 |
|
| 2010 |
Gulyás B, Tóth M, Varrone A, Horváth A, Laszlovszky I, Kiss B, Halldin C. BRAIN DISTRIBUTION AND BINDING OF [11C]CARIPRAZINE: IN VIVO PET STUDIES IN NON-HUMAN PRIMATES AND WHOLE HEMISPHERE POSTMORTEM AUTORADIOGRAPHIC STUDIES IN HUMAN BRAIN SLICES Schizophrenia Research. 117: 258-259. DOI: 10.1016/J.Schres.2010.02.405 |
0.628 |
|
| 2010 |
Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C. Kinetic analysis and quantification of the dopamine transporter in the non-human primate brain with [11C]PE2I and [18F]FE-PE2I Neuroimage. 52. DOI: 10.1016/J.Neuroimage.2010.04.137 |
0.42 |
|
| 2010 |
Nilsson MS, Tóth M, Cselény Z, Karlsson P, Halldin C, Farde L, Varrone A. Poster Presentation No.: P093 MethodologyQuantification of serotonin transporter availability with [11C]MADAM — A comparison between the ECAT HRRT and HR systems Neuroimage. 52. DOI: 10.1016/J.Neuroimage.2010.04.134 |
0.304 |
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| 2010 |
Cselényi Z, Jönhagen ME, Forsberg A, Halldin C, Julin P, Schou M, Johnström P, Varnäs K, Svensson S, Farde L. Quantification and wavelet-aided parametric imaging of cerebral amyloid using the HRRT PET-system and [18F]AZD4694 Neuroimage. 52: S142. DOI: 10.1016/J.Neuroimage.2010.04.116 |
0.371 |
|
| 2010 |
Juréus A, Swahn B, Sandell J, Jeppsson F, Neelissen JA, Halldin C, Johnström P, Schou M, Cselényi Z, Farde L, Svensson SP. [18F]AZD4694—A new PET radioligand for sensitive detection of β-amyloid deposits Neuroimage. 52: S126. DOI: 10.1016/J.Neuroimage.2010.04.103 |
0.327 |
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| 2010 |
Andersson J, Seneca N, Truong P, Wensbo D, McLeod D, Raboisson P, Farde L, Halldin C. The novel mGluR5 radioligand [11C]AZ11696415: Palladium mediated 11C-cyanation and initial in vivo characterization in the cynomolgus monkey brain using positron emission tomography (PET) Neuroimage. 52: S122. DOI: 10.1016/J.Neuroimage.2010.04.100 |
0.489 |
|
| 2010 |
Nag S, Lehmann L, Kettschau G, Heinrich T, Brumby T, Thiele A, Varrone A, Gulyas B, Halldin C. Synthesis of three F-18 labeled analogues of l-deprenyl for PET studies of monoamine oxidase B Neuroimage. 52: S121. DOI: 10.1016/J.Neuroimage.2010.04.099 |
0.555 |
|
| 2010 |
Varrone A, Tóth M, Stepanov V, Nakao R, Gulyás B, Emond P, Deloye JB, Vercouillie J, Halldin C, Guilloteau D. Quantification of [18F]LBT-999 binding to the dopamine transporter in the rhesus monkey brain with the HRRT system Neuroimage. 52: S118-S119. DOI: 10.1016/J.Neuroimage.2010.04.097 |
0.595 |
|
| 2010 |
Takano A, Gulyás B, Halldin C. Clomipramine and the active metabolite, desmethylclomipramine, occupy NET in non-human primate measured by PET Neuroimage. 52: S106. DOI: 10.1016/J.Neuroimage.2010.04.085 |
0.564 |
|
| 2010 |
Tóth M, Varrone A, Jia Z, Horváth A, Laszlovszky I, Kiss B, Halldin C, Gulyás B. PET studies in cynomolgous monkeys and whole hemisphere post mortem autoradiographic studies in human brain slices with the dopamine D2/D3 receptor ligand 11C-cariprazine Neuroimage. 52: S100. DOI: 10.1016/J.Neuroimage.2010.04.080 |
0.651 |
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| 2010 |
Kodaka F, Ito H, Takano H, Takahashi H, Arakawa R, Fujie S, Sasaki T, Nakayama K, Halldin C, Farde L, Suhara T. Regional distribution of high and low affinity states of dopamine D2/3 receptor binding in humans: A PET study using [11C]MNPA and [11C]raclopride Neuroimage. 52: S95. DOI: 10.1016/J.Neuroimage.2010.04.076 |
0.498 |
|
| 2010 |
der Aart Jv, Comley R, Gulyas B, Garnier M, Petrone M, Iavarone L, Halldin C, Rabiner E. GSK588045 occupancy of brain 5-HT1A receptors examined using [11C]WAY100635 PET Neuroimage. 52: S80. DOI: 10.1016/J.Neuroimage.2010.04.064 |
0.66 |
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| 2010 |
Finnema S, Varnäs K, Stepanov V, Varrone A, Gulyás B, Arponen E, Helin S, Solin O, Haaparanta M, Sallinen J, Ingman K, Scheinin M, Farde L, Halldin C. Amphetamine decreases binding of the novel alpha2C-adrenoreceptor radioligand [11C]ORM-13070 in monkey brain Neuroimage. 52: S61-S62. DOI: 10.1016/J.Neuroimage.2010.04.047 |
0.614 |
|
| 2010 |
Finnema S, Varrone A, Hwang T, Farde L, Halldin C. Confirmation of fenfluramine effect on 5-HT1B binding of [11C]AZ10419369 using an equilibrium approach Neuroimage. 52: S55. DOI: 10.1016/J.Neuroimage.2010.04.042 |
0.347 |
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| 2009 |
Donohue SR, Varnäs K, Jia Z, Gulyás B, Pike VW, Halldin C. Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors. Bioorganic & Medicinal Chemistry Letters. 19: 6209-12. PMID 19767206 DOI: 10.1016/J.Bmcl.2009.08.092 |
0.63 |
|
| 2009 |
Schou M, Steiger C, Varrone A, Guilloteau D, Halldin C. Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 19: 4843-5. PMID 19577467 DOI: 10.1016/J.Bmcl.2009.06.032 |
0.463 |
|
| 2009 |
Terry GE, Liow JS, Zoghbi SS, Hirvonen J, Farris AG, Lerner A, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Hong JS, Pike VW, Halldin C, Innis RB. Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand. Neuroimage. 48: 362-70. PMID 19573609 DOI: 10.1016/J.Neuroimage.2009.06.059 |
0.484 |
|
| 2009 |
Takano A, Gulyás B, Varrone A, Halldin C. Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S,S)-[18F]FMeNER-D2 and (S,S)-[11C]MeNER. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1885-91. PMID 19565240 DOI: 10.1007/S00259-009-1194-X |
0.57 |
|
| 2009 |
Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, Gulyás B, Halldin C. In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand. Synapse (New York, N.Y.). 63: 871-80. PMID 19562698 DOI: 10.1002/Syn.20670 |
0.624 |
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| 2009 |
Karlsson S, Nyberg L, Karlsson P, Fischer H, Thilers P, Macdonald S, Brehmer Y, Rieckmann A, Halldin C, Farde L, Bäckman L. Modulation of striatal dopamine D1 binding by cognitive processing. Neuroimage. 48: 398-404. PMID 19539768 DOI: 10.1016/J.Neuroimage.2009.06.030 |
0.357 |
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| 2009 |
Nyberg S, Jönhagen ME, Cselényi Z, Halldin C, Julin P, Olsson H, Freund-Levi Y, Andersson J, Varnäs K, Svensson S, Farde L. Detection of amyloid in Alzheimer's disease with positron emission tomography using [11C]AZD2184. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1859-63. PMID 19495746 DOI: 10.1007/S00259-009-1182-1 |
0.637 |
|
| 2009 |
Varrone A, Sjöholm N, Eriksson L, Gulyás B, Halldin C, Farde L. Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1639-50. PMID 19437012 DOI: 10.1007/S00259-009-1156-3 |
0.636 |
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| 2009 |
Trajkovska V, Kirkegaard L, Krey G, Marcussen AB, Thomsen MS, Chourbaji S, Brandwein C, Ridder S, Halldin C, Gass P, Knudsen GM, Aznar S. Activation of glucocorticoid receptors increases 5-HT2A receptor levels. Experimental Neurology. 218: 83-91. PMID 19379741 DOI: 10.1016/J.Expneurol.2009.04.008 |
0.338 |
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| 2009 |
Otsuka T, Ito H, Halldin C, Takahashi H, Takano H, Arakawa R, Okumura M, Kodaka F, Miyoshi M, Sekine M, Seki C, Nakao R, Suzuki K, Finnema S, Hirayasu Y, et al. Quantitative PET analysis of the dopamine D2 receptor agonist radioligand 11C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 703-10. PMID 19372485 DOI: 10.2967/Jnumed.108.058503 |
0.5 |
|
| 2009 |
Skinbjerg M, Ariano MA, Thorsell A, Heilig M, Halldin C, Innis RB, Sibley DR. Arrestin3 mediates D(2) dopamine receptor internalization. Synapse (New York, N.Y.). 63: 621-4. PMID 19309759 DOI: 10.1002/Syn.20636 |
0.32 |
|
| 2009 |
Takano A, Gulyás B, Varrone A, Maguire RP, Halldin C. Saturated norepinephrine transporter occupancy by atomoxetine relevant to clinical doses: a rhesus monkey study with (S,S)-[(18)F]FMeNER-D (2). European Journal of Nuclear Medicine and Molecular Imaging. 36: 1308-14. PMID 19300997 DOI: 10.1007/S00259-009-1118-9 |
0.594 |
|
| 2009 |
Skinbjerg M, Namkung Y, Halldin C, Innis RB, Sibley DR. Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors. Synapse (New York, N.Y.). 63: 462-75. PMID 19217026 DOI: 10.1002/Syn.20626 |
0.395 |
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| 2009 |
Tokunaga M, Seneca N, Shin RM, Maeda J, Obayashi S, Okauchi T, Nagai Y, Zhang MR, Nakao R, Ito H, Innis RB, Halldin C, Suzuki K, Higuchi M, Suhara T. Neuroimaging and physiological evidence for involvement of glutamatergic transmission in regulation of the striatal dopaminergic system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1887-96. PMID 19211895 DOI: 10.1523/Jneurosci.2559-08.2009 |
0.427 |
|
| 2009 |
Finnema SJ, Halldin C, Bang-Andersen B, Gulyás B, Bundgaard C, Wikström HV, Farde L. Dopamine D(2/3) receptor occupancy of apomorphine in the nonhuman primate brain--a comparative PET study with [11C]raclopride and [11C]MNPA. Synapse (New York, N.Y.). 63: 378-89. PMID 19173265 DOI: 10.1002/Syn.20615 |
0.65 |
|
| 2009 |
Odano I, Halldin C, Karlsson P, Varrone A, Airaksinen AJ, Krasikova RN, Farde L. [18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil. Neuroimage. 45: 891-902. PMID 19136064 DOI: 10.1016/J.Neuroimage.2008.12.005 |
0.486 |
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| 2009 |
Borg J, Henningsson S, Saijo T, Inoue M, Bah J, Westberg L, Lundberg J, Jovanovic H, Andrée B, Nordstrom AL, Halldin C, Eriksson E, Farde L. Serotonin transporter genotype is associated with cognitive performance but not regional 5-HT1A receptor binding in humans. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 783-92. PMID 19126263 DOI: 10.1017/S1461145708009759 |
0.399 |
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| 2009 |
Jovanovic H, Karlsson P, Cerin A, Halldin C, Nordström AL. 5-HT(1A) receptor and 5-HTT binding during the menstrual cycle in healthy women examined with [(11)C] WAY100635 and [(11)C] MADAM PET. Psychiatry Research. 172: 31-7. PMID 19118985 DOI: 10.1016/J.Pscychresns.2008.07.002 |
0.359 |
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| 2009 |
Andersson J, Truong P, Halldin C. In-target produced [11C]methane: Increased specific radioactivity. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 67: 106-10. PMID 19013077 DOI: 10.1016/J.Apradiso.2008.09.010 |
0.559 |
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| 2009 |
Gulyás B, Makkai B, Kása P, Gulya K, Bakota L, Várszegi S, Beliczai Z, Andersson J, Csiba L, Thiele A, Dyrks T, Suhara T, Suzuki K, Higuchi M, Halldin C. A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system. Neurochemistry International. 54: 28-36. PMID 18984021 DOI: 10.1016/J.Neuint.2008.10.001 |
0.71 |
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| 2009 |
Finnema SJ, Donohue SR, Zoghbi SS, Brown AK, Gulyás B, Innis RB, Halldin C, Pike VW. Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo. Synapse (New York, N.Y.). 63: 22-30. PMID 18925657 DOI: 10.1002/Syn.20578 |
0.682 |
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| 2009 |
Schou M, Zoghbi SS, Shetty HU, Shchukin E, Liow JS, Hong J, Andrée BA, Gulyás B, Farde L, Innis RB, Pike VW, Halldin C. Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 11: 23-30. PMID 18800204 DOI: 10.1007/S11307-008-0175-Y |
0.602 |
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| 2009 |
Krasikova RN, Andersson J, Truong P, Nag S, Shchukin EV, Halldin C. A fully automated one-pot synthesis of [carbonyl-11C]WAY-100635 for clinical PET applications. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 67: 73-8. PMID 18715791 DOI: 10.1016/J.Apradiso.2008.07.008 |
0.591 |
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| 2009 |
Gulyás B, Makkai B, Nagy K, Vas A, Kása P, Andersson J, Suhara T, Suzuki K, Higuchi M, Beliczai Z, Gulya K, Csiba L, Halldin C. In vitro evidence for competitive tspo binding of the imaging biomarker candidates vinpocetine and two iodinated daa1106 analogues in post mortem autoradiography experiments on whole hemisphere human brain slices Current Radiopharmaceuticals. 2: 42-48. DOI: 10.2174/1874471010902010042 |
0.611 |
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| 2009 |
Cervenka S, Halldin C, Farde L. P.1.06 Limbic dopamine D2-receptor binding and social desirability European Neuropsychopharmacology. 19: S7-S8. DOI: 10.1016/S0924-977X(09)70009-4 |
0.356 |
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| 2009 |
McCarthy DJ, Halldin C, Andersson JD, Pierson ME. Discovery of novel positron emission tomography tracers Annual Reports in Medicinal Chemistry. 44: 501-513. DOI: 10.1016/S0065-7743(09)04424-8 |
0.427 |
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| 2009 |
Sundgren-Andersson AK, Svensson SP, Swahn B, Juréus A, Sandell J, Johnson AE, Jeppsson F, Neelissen JA, Halldin C, Johnström P, Schou M, Cselényi Z, Farde L. P2-023: AZD4694: Fluorinated Positron Emission Tomography (PET) radioligand for detection of β-amyloid deposits Alzheimer's & Dementia. 5: P267-P268. DOI: 10.1016/J.Jalz.2009.04.332 |
0.347 |
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| 2009 |
Steiger C, Finnema SJ, Raus L, Schou M, Nakao R, Suzuki K, Pike VW, Wikström HV, Halldin C. A two-step one-pot radiosynthesis of the potent dopamine D 2/D3 agonist PET radioligand [11C]MNPA Journal of Labelled Compounds and Radiopharmaceuticals. 52: 158-165. DOI: 10.1002/Jlcr.1583 |
0.372 |
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| 2008 |
Beliczai Z, Varszegi S, Gulyas B, Halldin C, Kasa P, Gulya K. Immunohistoblot analysis on whole human hemispheres from normal and Alzheimer diseased brains. Neurochemistry International. 53: 181-3. PMID 18832000 DOI: 10.1016/J.Neuint.2008.09.002 |
0.527 |
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| 2008 |
Donohue SR, Krushinski JH, Pike VW, Chernet E, Phebus L, Chesterfield AK, Felder CC, Halldin C, Schaus JM. Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging. Journal of Medicinal Chemistry. 51: 5833-42. PMID 18800770 DOI: 10.1021/Jm800416M |
0.5 |
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| 2008 |
Donohue SR, Pike VW, Finnema SJ, Truong P, Andersson J, Gulyás B, Halldin C. Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors. Journal of Medicinal Chemistry. 51: 5608-16. PMID 18754613 DOI: 10.1021/Jm800329Z |
0.728 |
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| 2008 |
Seneca N, Zoghbi SS, Skinbjerg M, Liow JS, Hong J, Sibley DR, Pike VW, Halldin C, Innis RB. Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA. Synapse (New York, N.Y.). 62: 756-63. PMID 18651641 DOI: 10.1002/Syn.20549 |
0.49 |
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| 2008 |
Arakawa R, Okumura M, Ito H, Seki C, Takahashi H, Takano H, Nakao R, Suzuki K, Okubo Y, Halldin C, Suhara T. Quantitative analysis of norepinephrine transporter in the human brain using PET with (S,S)-18F-FMeNER-D2. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 1270-6. PMID 18632811 DOI: 10.2967/Jnumed.108.051292 |
0.465 |
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| 2008 |
Takano A, Varrone A, Gulyás B, Karlsson P, Tauscher J, Halldin C. Mapping of the norepinephrine transporter in the human brain using PET with (S,S)-[18F]FMeNER-D2. Neuroimage. 42: 474-82. PMID 18617423 DOI: 10.1016/J.Neuroimage.2008.05.040 |
0.62 |
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| 2008 |
Seneca N, Skinbjerg M, Zoghbi SS, Liow JS, Gladding RL, Hong J, Kannan P, Tuan E, Sibley DR, Halldin C, Pike VW, Innis RB. Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand. Synapse (New York, N.Y.). 62: 700-9. PMID 18566975 DOI: 10.1002/syn.20544 |
0.497 |
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| 2008 |
Airaksinen AJ, Nag S, Finnema SJ, Mukherjee J, Chattopadhyay S, Gulyás B, Farde L, Halldin C. [11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors. Bioorganic & Medicinal Chemistry. 16: 6467-73. PMID 18534857 DOI: 10.1016/J.Bmc.2008.05.039 |
0.663 |
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| 2008 |
Ciumas C, Wahlin TB, Jucaite A, Lindstrom P, Halldin C, Savic I. Reduced dopamine transporter binding in patients with juvenile myoclonic epilepsy. Neurology. 71: 788-94. PMID 18463366 DOI: 10.1212/01.Wnl.0000316120.70504.D5 |
0.363 |
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| 2008 |
Terry G, Liow JS, Chernet E, Zoghbi SS, Phebus L, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. Neuroimage. 41: 690-8. PMID 18456516 DOI: 10.1016/J.Neuroimage.2008.03.004 |
0.5 |
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| 2008 |
Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, ... ... Halldin C, et al. [11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain. Neuroimage. 41: 1075-85. PMID 18434202 DOI: 10.1016/J.Neuroimage.2008.02.063 |
0.762 |
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| 2008 |
Cervenka S, Bäckman L, Cselényi Z, Halldin C, Farde L. Associations between dopamine D2-receptor binding and cognitive performance indicate functional compartmentalization of the human striatum. Neuroimage. 40: 1287-95. PMID 18296072 DOI: 10.1016/J.Neuroimage.2007.12.063 |
0.399 |
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| 2008 |
Cervenka S, Halldin C, Farde L. Age-related diurnal effect on D2 receptor binding: a preliminary PET study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 671-8. PMID 18184446 DOI: 10.1017/S1461145707008358 |
0.442 |
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| 2008 |
Hirvonen J, Johansson J, Teräs M, Oikonen V, Lumme V, Virsu P, Roivainen A, Någren K, Halldin C, Farde L, Hietala J. Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1059-69. PMID 18183028 DOI: 10.1038/Sj.Jcbfm.9600607 |
0.504 |
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| 2008 |
Jovanovic H, Lundberg J, Karlsson P, Cerin A, Saijo T, Varrone A, Halldin C, Nordström AL. Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET. Neuroimage. 39: 1408-19. PMID 18036835 DOI: 10.1016/J.Neuroimage.2007.10.016 |
0.377 |
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| 2008 |
Takano A, Halldin C, Varrone A, Karlsson P, Sjöholm N, Stubbs JB, Schou M, Airaksinen AJ, Tauscher J, Gulyás B. Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S,S)-[18F]FMeNER-D2: a human whole-body PET study. European Journal of Nuclear Medicine and Molecular Imaging. 35: 630-6. PMID 18000665 DOI: 10.1007/S00259-007-0622-Z |
0.594 |
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| 2008 |
Takano A, Gulyás B, Varrone A, Karlsson P, Schou M, Airaksinen AJ, Vandenhende F, Tauscher J, Halldin C. Imaging the norepinephrine transporter with positron emission tomography: initial human studies with (S,S)-[18F]FMeNER-D2. European Journal of Nuclear Medicine and Molecular Imaging. 35: 153-7. PMID 17909794 DOI: 10.1007/S00259-007-0598-8 |
0.633 |
|
| 2008 |
Vas A, Shchukin Y, Karrenbauer VD, Cselényi Z, Kostulas K, Hillert J, Savic I, Takano A, Halldin C, Gulyás B. Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients. Journal of the Neurological Sciences. 264: 9-17. PMID 17727889 DOI: 10.1016/J.Jns.2007.07.018 |
0.648 |
|
| 2008 |
Nordstrom AL, Mansson M, Jovanovic H, Karlsson P, Halldin C, Farde L, Vanover KE, Hacksell U, Brann MR, Davis RE, Weiner DM. PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 163-71. PMID 17708779 DOI: 10.1017/S1461145707007869 |
0.443 |
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| 2008 |
Yasuno F, Brown AK, Zoghbi SS, Krushinski JH, Chernet E, Tauscher J, Schaus JM, Phebus LA, Chesterfield AK, Felder CC, Gladding RL, Hong J, Halldin C, Pike VW, Innis RB. The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 259-69. PMID 17392732 DOI: 10.1038/Sj.Npp.1301402 |
0.527 |
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| 2008 |
Donohue S, Zoghbi S, Yasuno F, Terry G, Gourley J, Innis R, Halldin C, Pike V. Radiosynthesis and Evaluation in Monkey of Three 11C-Labeled 1,5-Diarylpyrazoles as High Potency Candidate PET Radioligands for Cannabinoid Subtype-1 Receptors in Brain Current Radiopharmaceuticalse. 1: 93-102. DOI: 10.2174/1874471010801020093 |
0.506 |
|
| 2008 |
Nyberg S, Takano A, Jucaite A, Karlsson P, McCarthy D, Kågedal M, Eriksson H, Lee C, Halldin C, Farde L. P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects European Neuropsychopharmacology. 18: S270. DOI: 10.1016/S0924-977X(08)70352-3 |
0.366 |
|
| 2008 |
Jovanovic H, Andersson E, Karlsson P, Halldin C, Nordstöm A, Åsberg M, Farde L. P.3.24 Lower 5-HT1A receptor binding in patients with borderline personality disorder: a PET study using [11C]WAY100635 European Neuropsychopharmacology. 18: s82-s83. DOI: 10.1016/S0924-977X(08)70095-6 |
0.421 |
|
| 2008 |
Andersson J, Pierson M, Finnema S, Gulyás B, Medd A, Powell M, McCarthy D, Nyberg S, Heys R, Potts W, Seneca N, Mrzljak L, Farde L, Halldin C. [11C]AZ10419369: A selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET); Characterization in cynomolgus monkey brain Neuroimage. 41: T19. DOI: 10.1016/j.neuroimage.2008.04.193 |
0.614 |
|
| 2008 |
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analyses of [11C]AZ10419369 binding to 5-HT1B receptors in the human brain Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.073 |
0.467 |
|
| 2008 |
Takano A, Varrone A, Gulyás B, Karlsson P, Tauscher J, Halldin C. Mapping of the norepinephrine transporter in man using PET with (S,S)-[18F]FMeNER-D2 Neuroimage. 41: T103. DOI: 10.1016/J.Neuroimage.2008.04.072 |
0.504 |
|
| 2008 |
Steiger C, Finnema S, Wikström H, Gulyás B, Nakao R, Suzuki K, Farde L, Halldin C. Radiosynthesis of [11C]MNPA from the precursor (R)-(−)-2-hydroxy-10,11-acetonide-NPA and a preliminary test–retest PET analysis in monkey brain Neuroimage. 41: T102. DOI: 10.1016/j.neuroimage.2008.04.071 |
0.555 |
|
| 2008 |
Donohue SR, Finnema S, Truong P, Andersson J, Gulyás B, Pike V, Halldin C. Discovery and labeling of a homochiral high affinity 3,4-diarylpyrazoline as a candidate radioligand for in vivo imaging of cannabinoid type-1 receptors Neuroimage. 41: T90. DOI: 10.1016/J.Neuroimage.2008.04.059 |
0.356 |
|
| 2008 |
Varrone A, Sjoholm N, Gulyas B, Halldin C, Farde L. Advancement in PET quantification using 3D-OP-OSEM PSF reconstruction with the HRRT Neuroimage. 41: T85. DOI: 10.1016/J.Neuroimage.2008.04.054 |
0.558 |
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| 2008 |
Odano I, Sakaguchi K, Hosoya T, Varrone A, Savic I, Halldin C, Farde L. Automated system for parametric image analysis in neuroreceptor binding studies with PET Neuroimage. 41: T77. DOI: 10.1016/J.Neuroimage.2008.04.047 |
0.395 |
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| 2008 |
Donohue SR, Halldin C, Schou M, Hong J, Phebus L, Chernet E, Hitchcock SA, Gardinier KM, Ruley KM, Krushinski JH, Schaus J, Pike VW. Radiolabeling of a high potency cannabinoid subtype‐1 receptor ligand, N‐(4‐fluoro‐benzyl)‐4‐(3‐(piperidin‐1‐yl)‐indole‐1‐sulfonyl)benzamide (PipISB), with carbon‐11 or fluorine‐18 Journal of Labelled Compounds and Radiopharmaceuticals. 51: 146-152. DOI: 10.1002/Jlcr.1491 |
0.438 |
|
| 2008 |
Airaksinen AJ, Andersson J, Truong P, Karlsson O, Halldin C. Radiosynthesis of [11C]ximelagatran via palladium catalyzed [11C]cyanation Journal of Labelled Compounds and Radiopharmaceuticals. 51: 1-5. DOI: 10.1002/Jlcr.1461 |
0.335 |
|
| 2007 |
Schou M, Pike VW, Halldin C. Development of radioligands for imaging of brain norepinephrine transporters in vivo with positron emission tomography. Current Topics in Medicinal Chemistry. 7: 1806-16. PMID 17979789 DOI: 10.2174/156802607782507411 |
0.464 |
|
| 2007 |
Lundberg J, Borg J, Halldin C, Farde L. A PET study on regional coexpression of 5-HT1A receptors and 5-HTT in the human brain. Psychopharmacology. 195: 425-33. PMID 17874074 DOI: 10.1007/S00213-007-0928-3 |
0.465 |
|
| 2007 |
McCarron JA, Zoghbi SS, Shetty HU, Vermeulen ES, Wikström HV, Ichise M, Yasuno F, Halldin C, Innis RB, Pike VW. Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET. European Journal of Nuclear Medicine and Molecular Imaging. 34: 1670-82. PMID 17579853 DOI: 10.1007/S00259-007-0460-Z |
0.442 |
|
| 2007 |
Zhang MR, Kumata K, Maeda J, Haradahira T, Noguchi J, Suhara T, Halldin C, Suzuki K. N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain. Journal of Medicinal Chemistry. 50: 848-55. PMID 17300167 DOI: 10.1021/Jm061127N |
0.409 |
|
| 2007 |
Lundberg J, Christophersen JS, Petersen KB, Loft H, Halldin C, Farde L. PET measurement of serotonin transporter occupancy: a comparison of escitalopram and citalopram. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 777-85. PMID 17201996 DOI: 10.1017/S1461145706007486 |
0.412 |
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| 2007 |
Schou M, Pike VW, Sóvágó J, Gulyás B, Gallagher PT, Dobson DR, Walter MW, Rudyk H, Farde L, Halldin C. Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET. Bioorganic & Medicinal Chemistry. 15: 616-25. PMID 17123820 DOI: 10.1016/J.Bmc.2006.10.065 |
0.653 |
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| 2007 |
Shetty HU, Zoghbi SS, Liow JS, Ichise M, Hong J, Musachio JL, Halldin C, Seidel J, Innis RB, Pike VW. Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I. European Journal of Nuclear Medicine and Molecular Imaging. 34: 667-78. PMID 17096093 DOI: 10.1007/S00259-006-0277-1 |
0.429 |
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| 2007 |
Stepanov V, Schou M, Järv J, Halldin C. Synthesis of 3H-labeled N-(3-iodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(4-methylphenyl)nortropane (PE2I) and its interaction with mice striatal membrane fragments. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 65: 293-300. PMID 17081763 DOI: 10.1016/J.Apradiso.2006.09.003 |
0.331 |
|
| 2007 |
Saba W, Valette H, Schöllhorn-Peyronneau MA, Coulon C, Ottaviani M, Chalon S, Dolle F, Emond P, Halldin C, Helfenbein J, Madelmont JC, Deloye JB, Guilloteau D, Bottlaender M. [11C]LBT-999: a suitable radioligand for investigation of extra-striatal dopamine transporter with PET. Synapse (New York, N.Y.). 61: 17-23. PMID 17068778 DOI: 10.1002/Syn.20337 |
0.473 |
|
| 2007 |
Nyberg S, Takano A, Grimm S, Gulyas B, McCarthy D, Lee C, Goldstein J, Halldin C, Farde L. P.1.c.022 PET-measured D2, 5-HT2, and norepinephrine transporter (NET) occupancy by quetiapine and N-desalkyl-quetiapine in non-human primates European Neuropsychopharmacology. 17: S254-S255. DOI: 10.1016/S0924-977X(07)70346-2 |
0.402 |
|
| 2006 |
Talvik M, Nordström AL, Okubo Y, Olsson H, Borg J, Halldin C, Farde L. Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography. Psychiatry Research. 148: 165-73. PMID 17095199 DOI: 10.1016/J.Pscychresns.2006.05.009 |
0.4 |
|
| 2006 |
Jovanovic H, Cerin A, Karlsson P, Lundberg J, Halldin C, Nordström AL. A PET study of 5-HT1A receptors at different phases of the menstrual cycle in women with premenstrual dysphoria. Psychiatry Research. 148: 185-93. PMID 17085022 DOI: 10.1016/J.Pscychresns.2006.05.002 |
0.355 |
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| 2006 |
Vander Borght T, Asenbaum S, Bartenstein P, Halldin C, Kapucu O, Van Laere K, Varrone A, Tatsch K. EANM procedure guidelines for brain tumour imaging using labelled amino acid analogues. European Journal of Nuclear Medicine and Molecular Imaging. 33: 1374-80. PMID 16932934 DOI: 10.1007/S00259-006-0206-3 |
0.362 |
|
| 2006 |
Seneca N, Gulyás B, Varrone A, Schou M, Airaksinen A, Tauscher J, Vandenhende F, Kielbasa W, Farde L, Innis RB, Halldin C. Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2. Psychopharmacology. 188: 119-27. PMID 16896954 DOI: 10.1007/s00213-006-0483-3 |
0.629 |
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| 2006 |
Cselényi Z, Olsson H, Halldin C, Gulyás B, Farde L. A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [11C]FLB 457 and [11C]WAY 100635. Neuroimage. 32: 1690-708. PMID 16859930 DOI: 10.1016/J.Neuroimage.2006.02.053 |
0.595 |
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| 2006 |
Cervenka S, Pålhagen SE, Comley RA, Panagiotidis G, Cselényi Z, Matthews JC, Lai RY, Halldin C, Farde L. Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding. Brain : a Journal of Neurology. 129: 2017-28. PMID 16816393 DOI: 10.1093/Brain/Awl163 |
0.477 |
|
| 2006 |
Lundberg J, Halldin C, Farde L. Measurement of serotonin transporter binding with PET and [11C]MADAM: a test-retest reproducibility study. Synapse (New York, N.Y.). 60: 256-63. PMID 16752362 DOI: 10.1002/Syn.20297 |
0.472 |
|
| 2006 |
Musachio JL, Hong J, Ichise M, Seneca N, Brown AK, Liow JS, Halldin C, Innis RB, Pike VW, He R, Zhou J, Kozikowski AP. Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 3101-4. PMID 16621532 DOI: 10.1016/J.Bmcl.2006.03.066 |
0.431 |
|
| 2006 |
Borg J, Andrée B, Lundberg J, Halldin C, Farde L. Search for correlations between serotonin 5-HT1A receptor expression and cognitive functions--a strategy in translational psychopharmacology. Psychopharmacology. 185: 389-94. PMID 16541245 DOI: 10.1007/S00213-006-0329-Z |
0.362 |
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| 2006 |
Jucaite A, Odano I, Olsson H, Pauli S, Halldin C, Farde L. Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study. European Journal of Nuclear Medicine and Molecular Imaging. 33: 657-68. PMID 16514530 DOI: 10.1007/S00259-005-0027-9 |
0.5 |
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| 2006 |
Donohue SR, Halldin C, Pike VW. Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging. Bioorganic & Medicinal Chemistry. 14: 3712-20. PMID 16466922 DOI: 10.1016/J.Bmc.2006.01.047 |
0.413 |
|
| 2006 |
Seneca N, Finnema SJ, Farde L, Gulyás B, Wikström HV, Halldin C, Innis RB. Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride. Synapse (New York, N.Y.). 59: 260-9. PMID 16416444 DOI: 10.1002/Syn.20238 |
0.645 |
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| 2006 |
Chou YH, Halldin C, Farde L. Clozapine binds preferentially to cortical D1-like dopamine receptors in the primate brain: a PET study. Psychopharmacology. 185: 29-35. PMID 16395606 DOI: 10.1007/S00213-005-0219-9 |
0.461 |
|
| 2006 |
Chalon S, Hall H, Saba W, Garreau L, Dollé F, Halldin C, Emond P, Bottlaender M, Deloye JB, Helfenbein J, Madelmont JC, Bodard S, Mincheva Z, Besnard JC, Guilloteau D. Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2beta-carbomethoxy-3beta-(4'-tolyl)nortropane (LBT-999) as a highly promising fluorinated ligand for the dopamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 317: 147-52. PMID 16339913 DOI: 10.1124/Jpet.105.096792 |
0.4 |
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| 2006 |
Schou M, Sóvágó J, Pike VW, Gulyás B, Bøgesø KP, Farde L, Halldin C. Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 8: 1-8. PMID 16322935 DOI: 10.1007/S11307-005-0027-Y |
0.657 |
|
| 2006 |
Dollé F, Emond P, Mavel S, Demphel S, Hinnen F, Mincheva Z, Saba W, Valette H, Chalon S, Halldin C, Helfenbein J, Legaillard J, Madelmont JC, Deloye JB, Bottlaender M, et al. Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET. Bioorganic & Medicinal Chemistry. 14: 1115-25. PMID 16219467 DOI: 10.1016/J.Bmc.2005.09.035 |
0.452 |
|
| 2006 |
HERHOLZ K, NORDBERG A, MASDEU J, GERHARD A, EBMEIER K, PAPPATA S, PERANI D, VANLAERE K, HALLDIN C, SALMON E. Imaging of Neurotransmitter Deficits: New Potential Biomarkers for Alzheimer’s Disease? Neurorx. 3: 412-412. DOI: 10.1016/J.Nurx.2006.05.026 |
0.374 |
|
| 2006 |
Finnema S, Bang-Andersen B, Farde L, Gulyás B, Wikström H, Halldin C. Dopamine D2/D3 receptor occupancy of apomorphine evaluated with the agonist radioligand [11C]MNPA and the antagonist radioligand [11C]Raclopride. A PET evaluation in the non-human primate brain Neuroimage. 31: T120. DOI: 10.1016/J.Neuroimage.2006.04.106 |
0.498 |
|
| 2006 |
Seneca N, Liow JS, Zoghbi S, Musachio JL, Hong J, Pike VW, Halldin C, Innis RB. Imaging endogenous dopamine occupancy of the D2 receptor in rat brain with [11C]MNPA Neuroimage. 31. DOI: 10.1016/J.Neuroimage.2006.04.105 |
0.437 |
|
| 2006 |
Finnema S, Bang-Andersen B, Farde L, Jørgensen M, Gulyás B, Foged C, Wikström H, Halldin C. PET evaluation of the partial dopamine D1 receptor agonist radioligands R- and S-[11C]N-Methyl-NNC 01-0259 Neuroimage. 31: T114. DOI: 10.1016/J.Neuroimage.2006.04.100 |
0.442 |
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| 2006 |
Odano I, Farde L, Savic I, Ciumas C, Krasikova R, Airaksinen A, Karlsson P, Pauli S, Halldin C. Comparisons of central benzodiazepine receptor mapping tracers [18F]Flumazenil and [11C]Flumazenil presentation Neuroimage. 31: T88. DOI: 10.1016/J.Neuroimage.2006.04.076 |
0.387 |
|
| 2006 |
Odano I, Jucaite A, Olsson H, Karlsson P, Pauli S, Halldin C, Farde L. Dopamine transporter binding corrected for tissue heterogeneity and partial volume effect using [11C]PE2I and PET Neuroimage. 31: T87. DOI: 10.1016/J.Neuroimage.2006.04.075 |
0.44 |
|
| 2006 |
Sovago J, Farde L, Cervenka S, Halldin C, Gulyas B. Increasing the accuracy of in vivo quantification of dopamine-D2/D3 receptor binding in the human brain by partial volume effect correction Neuroimage. 31: T85. DOI: 10.1016/J.Neuroimage.2006.04.073 |
0.606 |
|
| 2006 |
Donohue S, Halldin C, Finnema S, Gulyas B, Pike V. Synthesis and in vivo evaluation of a new PET radioligand for imaging the cannabinoid type-1 (CB1) receptors Neuroimage. 31: T50. DOI: 10.1016/j.neuroimage.2006.04.041 |
0.536 |
|
| 2006 |
Airaksinen AJ, Finnema S, Nag S, Mukherjee J, Gulyás B, Halldin C. A new PET radioligand [11C]cyclopropyl-FLB 457 for imaging extrastriatal dopamine D2 receptors: Evaluation in monkey and comparison to [11C]FLB 457 and [11C]Fallypride Neuroimage. 31: T15. DOI: 10.1016/J.Neuroimage.2006.04.006 |
0.473 |
|
| 2006 |
Schou M, Pike VW, Varrone A, Gulyás B, Farde L, Halldin C. Synthesis and PET evaluation of (R)-[S-methyl-11C] thionisoxetine, a candidate radioligand for imaging brain norepinephrine transporters Journal of Labelled Compounds and Radiopharmaceuticals. 49: 1007-1019. DOI: 10.1002/Jlcr.1128 |
0.615 |
|
| 2006 |
Dollé F, Hinnen F, Emond P, Mavel S, Mincheva Z, Saba W, Schöllhorn-Peyronneau M, Valette H, Garreau L, Chalon S, Halldin C, Helfenbein J, Legaillard J, Madelmont J, Deloye J, et al. Radiosynthesis of [18F]LBT-999, a selective radioligand for the visualization of the dopamine transporter with PET Journal of Labelled Compounds and Radiopharmaceuticals. 49: 687-698. DOI: 10.1002/Jlcr.1092 |
0.401 |
|
| 2005 |
Lundberg J, Odano I, Olsson H, Halldin C, Farde L. Quantification of 11C-MADAM binding to the serotonin transporter in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 46: 1505-15. PMID 16157534 |
0.353 |
|
| 2005 |
Sóvágó J, Farde L, Halldin C, Schukin E, Schou M, Laszlovszky I, Kiss B, Gulyás B. Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [11C]RGH-1756. Brain Research Bulletin. 67: 219-24. PMID 16144658 DOI: 10.1016/J.Brainresbull.2005.06.034 |
0.668 |
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| 2005 |
Schou M, Halldin C, Pike VW, Mozley PD, Dobson D, Innis RB, Farde L, Hall H. Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 15: 517-20. PMID 16139169 DOI: 10.1016/J.Euroneuro.2005.01.007 |
0.431 |
|
| 2005 |
Halldin C, Lundberg J, Sóvágó J, Gulyás B, Guilloteau D, Vercouillie J, Emond P, Chalon S, Tarkiainen J, Hiltunen J, Farde L. [(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET. Synapse (New York, N.Y.). 58: 173-83. PMID 16138320 DOI: 10.1002/Syn.20189 |
0.663 |
|
| 2005 |
Seneca N, Andree B, Sjoholm N, Schou M, Pauli S, Mozley PD, Stubbs JB, Liow JS, Sovago J, Gulyás B, Innis R, Halldin C. Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates. Nuclear Medicine Communications. 26: 695-700. PMID 16000987 DOI: 10.1097/01.Mnm.0000171780.72908.E7 |
0.569 |
|
| 2005 |
Meschaks A, Lindstrom P, Halldin C, Farde L, Savic I. Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy. Archives of Neurology. 62: 946-50. PMID 15956165 DOI: 10.1001/Archneur.62.6.946 |
0.369 |
|
| 2005 |
McCarron JA, Marchais-Oberwinkler S, Pike VW, Tarkiainen J, Halldin C, Sóvagó J, Gulyas B, Wikström HV, Farde L. Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 7: 209-19. PMID 15912425 DOI: 10.1007/S11307-005-4127-5 |
0.646 |
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| 2005 |
Finnema SJ, Seneca N, Farde L, Shchukin E, Sóvágó J, Gulyás B, Wikström HV, Innis RB, Neumeyer JL, Halldin C. A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey. Nuclear Medicine and Biology. 32: 353-60. PMID 15878504 DOI: 10.1016/J.Nucmedbio.2005.01.007 |
0.632 |
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| 2005 |
Gulyás B, Halldin C, Vas A, Banati RB, Shchukin E, Finnema S, Tarkainen J, Tihanyi K, Szilágyi G, Farde L. [11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies. Journal of the Neurological Sciences. 229: 219-23. PMID 15760643 DOI: 10.1016/J.Jns.2004.11.032 |
0.658 |
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| 2005 |
Ghose S, Fujita M, Morrison P, Uhl G, Murphy DL, Mozley PD, Schou M, Halldin C, Innis R. Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters. Synapse (New York, N.Y.). 56: 100-4. PMID 15729740 DOI: 10.1002/Syn.20133 |
0.374 |
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| 2005 |
Ryzhikov NN, Seneca N, Krasikova RN, Gomzina NA, Shchukin E, Fedorova OS, Vassiliev DA, Gulyás B, Hall H, Savic I, Halldin C. Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography. Nuclear Medicine and Biology. 32: 109-16. PMID 15721755 DOI: 10.1016/J.Nucmedbio.2004.11.001 |
0.62 |
|
| 2005 |
Zhang MR, Maeda J, Ito T, Okauchi T, Ogawa M, Noguchi J, Suhara T, Halldin C, Suzuki K. Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[(18)F]fluoromethoxy-d(2)-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor. Bioorganic & Medicinal Chemistry. 13: 1811-8. PMID 15698799 DOI: 10.1016/J.Bmc.2004.11.058 |
0.385 |
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| 2005 |
Jucaite A, Fernell E, Halldin C, Forssberg H, Farde L. Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity. Biological Psychiatry. 57: 229-38. PMID 15691523 DOI: 10.1016/J.Biopsych.2004.11.009 |
0.356 |
|
| 2005 |
Marchais-Oberwinkler S, Nowicki B, Pike VW, Halldin C, Sandell J, Chou YH, Gulyas B, Brennum LT, Farde L, Wikström HV. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists. Bioorganic & Medicinal Chemistry. 13: 883-93. PMID 15653354 DOI: 10.1016/J.Bmc.2004.10.033 |
0.6 |
|
| 2005 |
Seneca N, Finnema S, Ichise M, Gulyas B, Wikstrom H, Innis RB, Farde L, Halldin C. Effect of amphetamine on dopamine D2 receptor binding in the primate brain with the agonist ligand [11C]MNPA Journal of Cerebral Blood Flow & Metabolism. 25: S646-S646. DOI: 10.1038/Sj.Jcbfm.9591524.0646 |
0.628 |
|
| 2004 |
Halldin C, Gulyás B, Farde L. PET for drug development. Ernst Schering Research Foundation Workshop. 95-109. PMID 15248518 |
0.482 |
|
| 2004 |
Cselényi Z, Lundberg J, Halldin C, Farde L, Gulyás B. Joint explorative analysis of neuroreceptor subsystems in the human brain: application to receptor-transporter correlation using PET data. Neurochemistry International. 45: 773-81. PMID 15234122 DOI: 10.1016/J.Neuint.2003.12.005 |
0.598 |
|
| 2004 |
Sóvágó J, Farde L, Halldin C, Langer O, Laszlovszky I, Kiss B, Gulyás B. Positron emission tomographic evaluation of the putative dopamine-D3 receptor ligand, [11C]RGH-1756 in the monkey brain. Neurochemistry International. 45: 609-17. PMID 15234102 DOI: 10.1016/J.Neuint.2004.04.004 |
0.67 |
|
| 2004 |
Varnäs K, Halldin C, Hall H. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Human Brain Mapping. 22: 246-60. PMID 15195291 DOI: 10.1002/Hbm.20035 |
0.325 |
|
| 2004 |
Olsson H, Halldin C, Farde L. Differentiation of extrastriatal dopamine D2 receptor density and affinity in the human brain using PET. Neuroimage. 22: 794-803. PMID 15193608 DOI: 10.1016/J.Neuroimage.2004.02.002 |
0.467 |
|
| 2004 |
Schou M, Halldin C, Sóvágó J, Pike VW, Hall H, Gulyás B, Mozley PD, Dobson D, Shchukin E, Innis RB, Farde L. PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain. Synapse (New York, N.Y.). 53: 57-67. PMID 15170818 DOI: 10.1002/Syn.20031 |
0.597 |
|
| 2004 |
Yasuno F, Suhara T, Okubo Y, Sudo Y, Inoue M, Ichimiya T, Takano A, Nakayama K, Halldin C, Farde L. Low dopamine d(2) receptor binding in subregions of the thalamus in schizophrenia. The American Journal of Psychiatry. 161: 1016-22. PMID 15169689 DOI: 10.1176/Appi.Ajp.161.6.1016 |
0.378 |
|
| 2004 |
Savic I, Lindström P, Gulyás B, Halldin C, Andrée B, Farde L. Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy. Neurology. 62: 1343-51. PMID 15111672 DOI: 10.1212/01.Wnl.0000123696.98166.Af |
0.593 |
|
| 2004 |
Balle T, Halldin C, Andersen L, Hjorth Alifrangis L, Badolo L, Gjervig Jensen K, Chou YW, Andersen K, Perregaard J, Farde L. New alpha(1)-adrenoceptor antagonists derived from the antipsychotic sertindole - carbon-11 labelling and pet examination of brain uptake in the cynomolgus monkey. Nuclear Medicine and Biology. 31: 327-36. PMID 15028245 DOI: 10.1016/J.Nucmedbio.2003.08.012 |
0.474 |
|
| 2004 |
McCarron JA, Pike VW, Halldin C, Sandell J, Sóvágó J, Gulyas B, Cselényi Z, Wikström HV, Marchais-Oberwinkler S, Nowicki B, Dollé F, Farde L. The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 6: 17-26. PMID 15018825 DOI: 10.1016/J.Mibio.2003.12.001 |
0.612 |
|
| 2004 |
Talvik M, Nordström AL, Larsen NE, Jucaite A, Cervenka S, Halldin C, Farde L. A cross-validation study on the relationship between central D2 receptor occupancy and serum perphenazine concentration. Psychopharmacology. 175: 148-53. PMID 15007534 DOI: 10.1007/S00213-004-1802-1 |
0.382 |
|
| 2004 |
Larsen AK, Brennum LT, Egebjerg J, Sánchez C, Halldin C, Andersen PH. Selectivity of (3)H-MADAM binding to 5-hydroxytryptamine transporters in vitro and in vivo in mice; correlation with behavioural effects. British Journal of Pharmacology. 141: 1015-23. PMID 14993096 DOI: 10.1038/Sj.Bjp.0705693 |
0.349 |
|
| 2004 |
Eskola O, Grönroos T, Bergman J, Haaparanta M, Marjamäki P, Lehikoinen P, Forsback S, Langer O, Hinnen F, Dollé F, Halldin C, Solin O. A novel electrophilic synthesis and evaluation of medium specific radioactivity (1R,2S)-4-[18F]fluorometaraminol, a tracer for the assessment of cardiac sympathetic nerve integrity with PET. Nuclear Medicine and Biology. 31: 103-10. PMID 14741575 DOI: 10.1016/S0969-8051(03)00098-2 |
0.325 |
|
| 2003 |
Talvik M, Nordström AL, Olsson H, Halldin C, Farde L. Decreased thalamic D2/D3 receptor binding in drug-naive patients with schizophrenia: a PET study with [11C]FLB 457. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 6: 361-70. PMID 14604451 DOI: 10.1017/S1461145703003699 |
0.39 |
|
| 2003 |
Pike VW, Halldin C, Nobuhara K, Hiltunen J, Mulligan RS, Swahn CG, Karlsson P, Olsson H, Hume SP, Hirani E, Whalley J, Pilowsky LS, Larsson S, Schnell PO, Ell PJ, et al. Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1520-8. PMID 14579092 DOI: 10.1007/S00259-003-1307-X |
0.443 |
|
| 2003 |
Schou M, Halldin C, Sóvágó J, Pike VW, Gulyás B, Mozley PD, Johnson DP, Hall H, Innis RB, Farde L. Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER. Nuclear Medicine and Biology. 30: 707-14. PMID 14499328 DOI: 10.1016/S0969-8051(03)00079-9 |
0.609 |
|
| 2003 |
Varnäs K, Halldin C, Pike VW, Hall H. Distribution of 5-HT4 receptors in the postmortem human brain--an autoradiographic study using [125I]SB 207710. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 13: 228-34. PMID 12888181 DOI: 10.1016/S0924-977X(03)00009-9 |
0.428 |
|
| 2003 |
Halldin C, Erixon-Lindroth N, Pauli S, Chou YH, Okubo Y, Karlsson P, Lundkvist C, Olsson H, Guilloteau D, Emond P, Farde L. [(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1220-30. PMID 12811422 DOI: 10.1007/S00259-003-1212-3 |
0.498 |
|
| 2003 |
Karramkam M, Hinnen F, Berrehouma M, Hlavacek C, Vaufrey F, Halldin C, McCarron JA, Pike VW, Dollé F. Synthesis of a [6-pyridinyl-18F]-labelled fluoro derivative of WAY-100635 as a candidate radioligand for brain 5-HT1A receptor imaging with PET. Bioorganic & Medicinal Chemistry. 11: 2769-82. PMID 12788351 DOI: 10.1016/S0968-0896(03)00225-6 |
0.427 |
|
| 2003 |
Andrée B, Hedman A, Thorberg SO, Nilsson D, Halldin C, Farde L. Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain. Psychopharmacology. 167: 37-45. PMID 12632244 DOI: 10.1007/S00213-002-1355-0 |
0.386 |
|
| 2003 |
Chou YH, Halldin C, Farde L. Occupancy of 5-HT1A receptors by clozapine in the primate brain: a PET study. Psychopharmacology. 166: 234-40. PMID 12589516 DOI: 10.1007/S00213-002-1256-2 |
0.418 |
|
| 2003 |
Chalon S, Tarkiainen J, Garreau L, Hall H, Emond P, Vercouillie J, Farde L, Dasse P, Varnas K, Besnard JC, Halldin C, Guilloteau D. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity. The Journal of Pharmacology and Experimental Therapeutics. 304: 81-7. PMID 12490578 DOI: 10.1124/Jpet.102.042226 |
0.388 |
|
| 2003 |
Talvik M, Nordström A, Olsson H, Halldin C, Farde L. P.2.115 PET examinations or thalamic D2 receptors in schizophrenic patients European Neuropsychopharmacology. 13: S330. DOI: 10.1016/S0924-977X(03)92068-2 |
0.4 |
|
| 2003 |
Langer O, Forngren T, Sandell J, Dollé F, Långström B, Någren K, Halldin C. Preparation of 4-[11C]methylmetaraminol, a potential PET tracer for assessment of myocardial sympathetic innervation: PREPARATION OF 4-[11C] METHYLMETARAMINOL Journal of Labelled Compounds and Radiopharmaceuticals. 46: 55-65. DOI: 10.1002/Jlcr.642 |
0.404 |
|
| 2003 |
Langer O, Forngren T, Sandell J, Dollé F, Långström B, N̊gren K, Halldin C. Preparation of 4-[11C]methylmetaraminol, a potential PET tracer for assessment of myocardial sympathetic innervation Journal of Labelled Compounds and Radiopharmaceuticals. 46: 55-65. DOI: 10.1002/Jlcr.25804401146 |
0.412 |
|
| 2002 |
Vas A, Sóvágó J, Halldin C, Sandell J, Karlsson P, Kárpáti E, Kiss B, Cselényi Z, Farde L, Gulyás B. [Cerebral uptake and regional distribution of [11C]-vinpocetin after intravenous administration to healthy men: a PET study]. Orvosi Hetilap. 143: 2631-6. PMID 12532649 |
0.587 |
|
| 2002 |
Gulyás B, Halldin C, Sandell J, Karlsson P, Sóvágó J, Kárpáti E, Kiss B, Vas A, Cselényi Z, Farde L. PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects. Acta Neurologica Scandinavica. 106: 325-32. PMID 12460136 DOI: 10.1034/J.1600-0404.2002.01302.X |
0.618 |
|
| 2002 |
Sandell J, Yu M, Emond P, Garreau L, Chalon S, Någren K, Guilloteau D, Halldin C. Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter. Bioorganic & Medicinal Chemistry Letters. 12: 3611-3. PMID 12443787 DOI: 10.1016/S0960-894X(02)00787-4 |
0.363 |
|
| 2002 |
Gulyás B, Vas A, Halldin C, Sóvágó J, Sandell J, Olsson H, Fredriksson A, Stone-Elander S, Farde L. Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study. Nuclear Medicine and Biology. 29: 753-9. PMID 12381455 DOI: 10.1016/S0969-8051(02)00319-0 |
0.586 |
|
| 2002 |
Sandell J, Halldin C, Sovago J, Chou YH, Gulyás B, Yu M, Emond P, Någren K, Guilloteau D, Farde L. PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter. Nuclear Medicine and Biology. 29: 651-6. PMID 12234589 DOI: 10.1016/S0969-8051(02)00318-9 |
0.648 |
|
| 2002 |
Gulyás B, Halldin C, Sóvágó J, Sandell J, Cselényi Z, Vas A, Kiss B, Kárpáti E, Farde L. Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine. European Journal of Nuclear Medicine and Molecular Imaging. 29: 1031-8. PMID 12173017 DOI: 10.1007/S00259-002-0823-4 |
0.59 |
|
| 2002 |
Nyberg S, Olsson H, Nilsson U, Maehlum E, Halldin C, Farde L. Low striatal and extra-striatal D2 receptor occupancy during treatment with the atypical antipsychotic sertindole. Psychopharmacology. 162: 37-41. PMID 12107615 DOI: 10.1007/S00213-002-1083-5 |
0.435 |
|
| 2002 |
Hall H, Varnäs K, Sandell J, Halldin C, Farde L, Vas A, Kárpáti E, Gulyás B. Autoradiographic evaluation of [11C]vinpocetine binding in the human postmortem brain. Acta Biologica Hungarica. 53: 59-66. PMID 12064779 DOI: 10.1556/ABiol.53.2002.1-2.7 |
0.576 |
|
| 2002 |
Nyberg S, Chou YH, Halldin C. Saturation of striatal D(2) dopamine receptors by clozapine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 5: 11-6. PMID 12057028 DOI: 10.1017/S1461145701002693 |
0.415 |
|
| 2002 |
Drews A, Pietzsch HJ, Syhre R, Seifert S, Varnäs K, Hall H, Halldin C, Kraus W, Karlsson P, Johnsson C, Spies H, Johannsen B. Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT(1A) receptor and the alpha1-adrenergic receptor. Nuclear Medicine and Biology. 29: 389-98. PMID 12031873 DOI: 10.1016/S0969-8051(02)00296-2 |
0.387 |
|
| 2002 |
Heimbold I, Drews A, Kretzschmar M, Varnäs K, Hall H, Halldin C, Syhre R, Kraus W, Pietzsch HJ, Seifert S, Brust P, Johannsen B. Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT(1A) receptor and the alpha1-adrenergic receptor. Nuclear Medicine and Biology. 29: 375-87. PMID 12031872 DOI: 10.1016/S0969-8051(01)00313-4 |
0.371 |
|
| 2002 |
Langer O, Halldin C. PET and SPET tracers for mapping the cardiac nervous system. European Journal of Nuclear Medicine and Molecular Imaging. 29: 416-34. PMID 12002720 DOI: 10.1007/S002590100640 |
0.369 |
|
| 2002 |
Karlsson P, Farde L, Halldin C, Sedvall G. PET study of D(1) dopamine receptor binding in neuroleptic-naive patients with schizophrenia. The American Journal of Psychiatry. 159: 761-7. PMID 11986129 DOI: 10.1176/Appi.Ajp.159.5.761 |
0.453 |
|
| 2002 |
Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 43: 292-303. PMID 11884487 |
0.396 |
|
| 2002 |
Emond P, Vercouillie J, Innis R, Chalon S, Mavel S, Frangin Y, Halldin C, Besnard JC, Guilloteau D. Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation. Journal of Medicinal Chemistry. 45: 1253-8. PMID 11881994 DOI: 10.1021/Jm010939A |
0.376 |
|
| 2002 |
Sandell J, Halldin C, Chou YH, Swahn CG, Thorberg SO, Farde L. PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor. Nuclear Medicine and Biology. 29: 39-45. PMID 11786274 DOI: 10.1016/S0969-8051(01)00272-4 |
0.445 |
|
| 2002 |
Suhara T, Okubo Y, Yasuno F, Sudo Y, Inoue M, Ichimiya T, Nakashima Y, Nakayama K, Tanada S, Suzuki K, Halldin C, Farde L. Decreased dopamine D2 receptor binding in the anterior cingulate cortex in schizophrenia. Archives of General Psychiatry. 59: 25-30. PMID 11779278 DOI: 10.1001/Archpsyc.59.1.25 |
0.341 |
|
| 2002 |
Varnäs K, Hall H, Halldin C, Sedvall G. Autoradiographic localisation of 5-HT receptors in the human brain European Psychiatry. 17: 155. DOI: 10.1016/S0924-9338(02)80674-5 |
0.366 |
|
| 2002 |
Nordström A, Talvik M, Halldin C, Farde L. PET and antipsychotic drugs — background European Psychiatry. 17: 7-8. DOI: 10.1016/S0924-9338(02)80034-7 |
0.338 |
|
| 2001 |
Pike VW, Halldin C, Wikström HV. Radioligands for the study of brain 5-HT1A receptors in vivo. Progress in Medicinal Chemistry. 38: 189-247. PMID 11774795 DOI: 10.1016/S0079-6468(08)70094-8 |
0.451 |
|
| 2001 |
Halldin C, Gulyás B, Farde L. PET studies with carbon-11 radioligands in neuropsychopharmacological drug development. Current Pharmaceutical Design. 7: 1907-29. PMID 11772357 DOI: 10.2174/1381612013396871 |
0.579 |
|
| 2001 |
Sudo Y, Suhara T, Inoue M, Ito H, Suzuki K, Saijo T, Halldin C, Farde L. Reproducibility of [11 C]FLB 457 binding in extrastriatal regions. Nuclear Medicine Communications. 22: 1215-21. PMID 11606887 DOI: 10.1097/00006231-200111000-00008 |
0.493 |
|
| 2001 |
Halldin C, Gulyás B, Langer O, Farde L. Brain radioligands--state of the art and new trends. The Quarterly Journal of Nuclear Medicine : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar). 45: 139-52. PMID 11476163 |
0.617 |
|
| 2001 |
Halldin C. Serotonin 5-HT1A receptor imaging in the human brain with positron-emission tomography: coordination and the standardization and dissemination of methodology. Journal of Clinical Pharmacology. 95S. PMID 11452735 DOI: 10.1177/0091270001417013 |
0.448 |
|
| 2001 |
Talvik M, Nordström AL, Nyberg S, Olsson H, Halldin C, Farde L. No support for regional selectivity in clozapine-treated patients: a PET study with [(11)C]raclopride and [(11)C]FLB 457. The American Journal of Psychiatry. 158: 926-30. PMID 11384901 DOI: 10.1176/Appi.Ajp.158.6.926 |
0.465 |
|
| 2001 |
Marchais S, Nowicki B, Wikström H, Brennum LT, Halldin C, Pike VW. Short and efficient syntheses of analogues of WAY-100635: new and potent 5-HT1A receptor antagonists. Bioorganic & Medicinal Chemistry. 9: 695-702. PMID 11310604 DOI: 10.1016/S0968-0896(00)00287-X |
0.337 |
|
| 2001 |
Sandell J, Halldin C, Pike VW, Chou YH, Varnäs K, Hall H, Marchais S, Nowicki B, Wikström HV, Swahn CG, Farde L. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey. Nuclear Medicine and Biology. 28: 177-85. PMID 11295428 DOI: 10.1016/S0969-8051(00)00181-5 |
0.507 |
|
| 2001 |
Nobuhara K, Farde L, Halldin C, Karlsson P, Swahn CG, Olsson H, Bergström KA, Larsson SA, Schnell PO, McPherson DW, Savonen A, Hiltunen J, Sedvall G. SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP. European Journal of Nuclear Medicine. 28: 13-24. PMID 11202446 DOI: 10.1007/S002590000390 |
0.329 |
|
| 2001 |
Ito H, Sudo Y, Suhara T, Okubo Y, Halldin C, Farde L. Error analysis for quantification of [(11)C]FLB 457 binding to extrastriatal D(2) dopamine receptors in the human brain. Neuroimage. 13: 531-9. PMID 11170818 DOI: 10.1006/Nimg.2000.0717 |
0.459 |
|
| 2001 |
Hall H, Hurd Y, Pauli S, Halldin C, Sedvall G. Human brain imaging post-mortem - Whole hemisphere technologies International Review of Psychiatry. 13: 12-17. DOI: 10.1080/09540260124940 |
0.445 |
|
| 2001 |
Cselényi Z, Olsson H, Gulyás B, Halldin C, Farde L. Detailed mapping of dopamine D2 receptors in the human limbic system using FLB 457 binding analysis in wavelet space Neuroimage. 13: 1299. DOI: 10.1016/S1053-8119(01)92613-8 |
0.557 |
|
| 2001 |
Savic I, Gulyas B, Lindström P, Halldin C, Farde L. Mesial temporal lobe epilepsy is associated with limbic reductions in serotonin 5HT1A receptor binding Neuroimage. 13: 833. DOI: 10.1016/S1053-8119(01)92175-5 |
0.328 |
|
| 2001 |
Gulyás B, Halldin C, Sóvágó J, Sandell J, Cselényi Z, Karlsson P, Kárpáti E, Kiss B, Vas A, Farde L. A novel principle of radiotracer administration in human brain mapping: pet studies on brain uptake and distribution of orally and intravenously administered [11C]vinpocetine Neuroimage. 13: 12. DOI: 10.1016/S1053-8119(01)91355-2 |
0.616 |
|
| 2001 |
VERCOUILLIE J, TARKIAINEN J, HALLDIN C, EMOND P, CHALON S, SANDELL J, LANGER O, GUILLOTEAU D. Precursor synthesis and radiolabelling of [11C]ADAM: a potential radioligand for the serotonin transporter exploration by PET Journal of Labelled Compounds and Radiopharmaceuticals. 44: 113-120. DOI: 10.1002/Jlcr.436 |
0.434 |
|
| 2001 |
Halldin C, Dollé F, Hall H, Varnäs K, Sandell J, Demphel S, Crouzel C. Development of a central nicotinic acetylcholine receptor radioligand, 5-methyl-A-85380, and postmortem autoradiography in human brain Journal of Labelled Compounds and Radiopharmaceuticals. 44: S251-S253. DOI: 10.1002/Jlcr.2580440188 |
0.367 |
|
| 2001 |
Tarkiainen J, Vercouillie J, Guilloteau D, Gulyás B, Sóvágó J, Cselényi Z, Emond P, Chalon S, Sandell J, Hiltunen J, Farde L, Halldin C. Carbon-11 labelling of madam in two different positions: A highly selective pet radioligand for the serotonin transporter Journal of Labelled Compounds and Radiopharmaceuticals. 44: S193-S195. DOI: 10.1002/Jlcr.2580440167 |
0.361 |
|
| 2001 |
Sandell J, Mccarron JA, Halldin C, Pike VW, Gulyas B, Cselenyi Z, Sovago J, Marchais S, Wikström HV, Farde L. [18F]6FPWAY - a prospective 5-HT1A receptor radioligand - radiolabeling and pet examination in monkey - comparison with [11C]6FPWAY Journal of Labelled Compounds and Radiopharmaceuticals. 44: S167-S169. DOI: 10.1002/Jlcr.2580440158 |
0.468 |
|
| 2000 |
Farde L, Ginovart N, Halldin C, Chou YH, Olsson H, Swahn CG. A PET study of The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 3: 203-214. PMID 11343597 DOI: 10.1017/S1461145700002030 |
0.469 |
|
| 2000 |
Langer O, Halldin C, Chou Y, Sandell J, Swahn C, Någren K, Perrone R, Berardi F, Leopoldo M, Farde L. Carbon-11 pb-12: an attempt to visualize the dopamine d(4) receptor in the primate brain with positron emission tomography. Nuclear Medicine and Biology. 27: 707-14. PMID 11150701 DOI: 10.1016/S0969-8051(00)00154-2 |
0.402 |
|
| 2000 |
Hall H, Farde L, Halldin C, Lundkvist C, Sedvall G. Autoradiographic localization of 5-HT(2A) receptors in the human brain using [(3)H]M100907 and [(11)C]M100907. Synapse (New York, N.Y.). 38: 421-31. PMID 11044889 DOI: 10.1002/1098-2396(20001215)38:4<421::Aid-Syn7>3.0.Co;2-X |
0.379 |
|
| 2000 |
Chou YH, Halldin C, Farde L. Effect of amphetamine on extrastriatal D2 dopamine receptor binding in the primate brain: a PET study. Synapse (New York, N.Y.). 38: 138-43. PMID 11018787 DOI: 10.1002/1098-2396(200011)38:2<138::Aid-Syn4>3.0.Co;2-7 |
0.504 |
|
| 2000 |
Andrée B, Halldin C, Thorberg SO, Sandell J, Farde L. Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development. Nuclear Medicine and Biology. 27: 515-21. PMID 10962260 DOI: 10.1016/S0969-8051(00)00121-9 |
0.399 |
|
| 2000 |
Pike VW, Halldin C, Wikström H, Marchais S, McCarron JA, Sandell J, Nowicki B, Swahn CG, Osman S, Hume SP, Constantinou M, Andrée B, Farde L. Radioligands for the study of brain 5-HT(1A) receptors in vivo--development of some new analogues of way. Nuclear Medicine and Biology. 27: 449-55. PMID 10962249 DOI: 10.1016/S0969-8051(00)00110-4 |
0.475 |
|
| 2000 |
Talvik-Lotfi M, Nyberg S, Nordström AL, Ito H, Halldin C, Brunner F, Farde L. High 5HT2A receptor occupancy in M100907-treated schizophrenic patients. Psychopharmacology. 148: 400-3. PMID 10928313 DOI: 10.1007/S002130050069 |
0.323 |
|
| 2000 |
Langer O, Valette H, Dollé F, Halldin C, Loc'h C, Fuseau C, Coulon C, Ottaviani M, Bottlaender M, Mazière B, Crouzel C. High specific radioactivity (1R,2S)-4-[(18)F]fluorometaraminol: a PET radiotracer for mapping sympathetic nerves of the heart. Nuclear Medicine and Biology. 27: 233-8. PMID 10832079 DOI: 10.1016/S0969-8051(00)00082-2 |
0.36 |
|
| 2000 |
Pinborg LH, Videbaek C, Knudsen GM, Swahn CG, Halldin C, Friberg L, Paulson OB, Lassen NA. Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion. Synapse (New York, N.Y.). 36: 322-9. PMID 10819910 DOI: 10.1002/(Sici)1098-2396(20000615)36:4<322::Aid-Syn9>3.0.Co;2-W |
0.4 |
|
| 2000 |
Nobuhara K, Halldin C, Hall H, Karlsson P, Farde L, Hiltunen J, McPherson DW, Savonen A, Bergström KA, Pauli S, Swahn CG, Larsson SA, Schnell PO, Sedvall G. Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer's disease. Psychopharmacology. 149: 45-55. PMID 10789882 DOI: 10.1007/S002139900356 |
0.402 |
|
| 2000 |
Bergström KA, Yu M, Kuikka JT, Akerman KK, Hiltunen J, Lehtonen J, Halldin C, Tiihonen J. Metabolism of [123I]epidepride may affect brain dopamine D2 receptor imaging with single-photon emission tomography. European Journal of Nuclear Medicine. 27: 206-8. PMID 10755727 DOI: 10.1007/S002590050028 |
0.448 |
|
| 2000 |
Kaasinen V, NÃ¥gren K, Hietala J, Oikonen V, Vilkman H, Farde L, Halldin C, Rinne JO. Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson's disease. Neurology. 54: 1482-7. PMID 10751262 DOI: 10.1212/Wnl.54.7.1482 |
0.367 |
|
| 2000 |
Bäckman L, Ginovart N, Dixon RA, Wahlin TB, Wahlin A, Halldin C, Farde L. Age-related cognitive deficits mediated by changes in the striatal dopamine system. The American Journal of Psychiatry. 157: 635-7. PMID 10739428 DOI: 10.1176/Ajp.157.4.635 |
0.303 |
|
| 2000 |
Farde L, Andrée B, Ginovart N, Halldin C, Thorberg S. PET-Determination of robalzotan (NAD-299) induced 5-HT(1A) receptor occupancy in the monkey brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 422-9. PMID 10700661 DOI: 10.1016/S0893-133X(99)00125-6 |
0.387 |
|
| 2000 |
Abi-Dargham A, Martinez D, Mawlawi O, Simpson N, Hwang D, Slifstein M, Anjilvel S, Pidcock J, Guo N, Lombardo I, Mann JJ, Heertum RV, Foged C, Halldin C, Laruelle M. Measurement of striatal and extrastriatal dopamine D1 receptor binding potential with [11C]NNC 112 in humans: validation and reproducibility. Journal of Cerebral Blood Flow and Metabolism. 20: 225-243. PMID 10698059 DOI: 10.1097/00004647-200002000-00003 |
0.413 |
|
| 2000 |
Osterlund MK, Halldin C, Hurd YL. Effects of chronic 17beta-estradiol treatment on the serotonin 5-HT(1A) receptor mRNA and binding levels in the rat brain. Synapse (New York, N.Y.). 35: 39-44. PMID 10579806 DOI: 10.1002/(Sici)1098-2396(200001)35:1<39::Aid-Syn5>3.0.Co;2-T |
0.332 |
|
| 2000 |
Kämäräinen EL, Kyllönen T, Airaksinen A, Lundkvist C, Yu M, Någren K, Sandell J, Langer O, Vepsäläinen J, Hiltunen J, Bergström K, Lötjönen S, Jaakkola T, Halldin C. Preparation of [ 18F]β-CFT-FP and [ 11C]β-CFT-FP, selective radioligands for visualisation of the dopamine transporter using Positron Emission Tomography (PET) Journal of Labelled Compounds and Radiopharmaceuticals. 43: 1235-1244. DOI: 10.1002/1099-1344(20001030)43:12<1235::Aid-Jlcr411>3.0.Co;2-9 |
0.367 |
|
| 2000 |
Langer O, Gulyás B, Sandell J, Laszlovszky I, Kiss B, Domány G, Ács T, Farde L, Halldin C. Radiochemical labelling of the dopamine D3 receptor ligand RGH-1756 Journal of Labelled Compounds and Radiopharmaceuticals. 43: 1069-1074. DOI: 10.1002/1099-1344(20001015)43:11<1069::Aid-Jlcr390>3.0.Co;2-N |
0.647 |
|
| 2000 |
Dolle F, Bottlaender M, Demphel S, Emond P, Fuseau C, Coulon C, Ottaviani M, Valette H, Loc'h C, Halldin C, Mauclaire L, Guilloteau D, Maziere B, Crouzel C. Highly efficient synthesis of [11C]PE2I, a selective radioligand for the quantification of the dopamine transporter using PET Journal of Labelled Compounds and Radiopharmaceuticals. 43: 997-1004. DOI: 10.1002/1099-1344(200009)43:10<997::Aid-Jlcr385>3.0.Co;2-# |
0.445 |
|
| 2000 |
Sandell J, Halldin C, Helfenbein J, Chou Y, Vercouillie J, Emond P, Swahn C, Guilloteau D, Farde L. Synthesis of [11C]2?-carbomethoxy-3?-(3?-iodo-4?-methyl, -ethyl and isopropyl phenyl)nortropane as potential radiotracers for examination of the serotonin transporter with positron emission tomography Journal of Labelled Compounds and Radiopharmaceuticals. 43: 1033-1046. DOI: 10.1002/1099-1344(200009)43:10<1033::Aid-Jlcr389>3.0.Co;2-5 |
0.438 |
|
| 1999 |
Suhara T, Sudo Y, Okauchi T, Maeda J, Kawabe K, Suzuki K, Okubo Y, Nakashima Y, Ito H, Tanada S, Halldin C, Farde L. Extrastriatal dopamine D2 receptor density and affinity in the human brain measured by 3D PET. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 2: 73-82. PMID 11281973 DOI: 10.1017/S1461145799001431 |
0.466 |
|
| 1999 |
Okubo Y, Olsson H, Ito H, Lofti M, Suhara T, Halldin C, Farde L. PET mapping of extrastriatal D2-like dopamine receptors in the human brain using an anatomic standardization technique and [11C]FLB 457. Neuroimage. 10: 666-74. PMID 10600412 DOI: 10.1006/Nimg.1999.0502 |
0.501 |
|
| 1999 |
Bergström KA, Halldin C, Savonen A, Okubo Y, Hiltunen J, Nobuhara K, Swahn CG, Karlsson P, McPherson D, Knapp FF, Larsson S, Schnell PO, Farde L. Iodine-123 labelled Z-(R,R)-IQNP: a potential radioligand for visualization of M(1 )and M(2) muscarinic acetylcholine receptors in Alzheimer's disease. European Journal of Nuclear Medicine. 26: 1482-5. PMID 10552091 DOI: 10.1007/S002590050482 |
0.375 |
|
| 1999 |
Gulyás B, Halldin C, Karlsson P, Chou YH, Swahn CG, Bönöck P, Paróczai M, Farde L. Brain uptake and plasma metabolism of [11C]vinpocetine: a preliminary PET study in a cynomolgus monkey. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 9: 217-22. PMID 10540601 DOI: 10.1111/Jon199994217 |
0.629 |
|
| 1999 |
Olsson H, Halldin C, Swahn CG, Farde L. Quantification of [11C]FLB 457 binding to extrastriatal dopamine receptors in the human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1164-73. PMID 10532641 DOI: 10.1097/00004647-199910000-00013 |
0.517 |
|
| 1999 |
Chou YH, Karlsson P, Halldin C, Olsson H, Farde L. A PET study of D(1)-like dopamine receptor ligand binding during altered endogenous dopamine levels in the primate brain. Psychopharmacology. 146: 220-7. PMID 10525759 DOI: 10.1007/S002130051110 |
0.439 |
|
| 1999 |
Langer O, Halldin C, Dollé F, Swahn CG, Olsson H, Karlsson P, Hall H, Sandell J, Lundkvist C, Vaufrey F, Loc'h C, Crouzel C, Mazière B, Farde L. Carbon-11 epidepride: a suitable radioligand for PET investigation of striatal and extrastriatal dopamine D2 receptors. Nuclear Medicine and Biology. 26: 509-18. PMID 10473189 DOI: 10.1016/S0969-8051(99)00005-0 |
0.438 |
|
| 1999 |
Lundkvist C, Loc'h C, Halldin C, Bottlaender M, Ottaviani M, Coulon C, Fuseau C, Mathis C, Farde L, Mazière B. Characterization of bromine-76-labelled 5-bromo-6-nitroquipazine for PET studies of the serotonin transporter. Nuclear Medicine and Biology. 26: 501-7. PMID 10473188 DOI: 10.1016/S0969-8051(99)00019-0 |
0.478 |
|
| 1999 |
Helfenbein J, Sandell J, Halldin C, Chalon S, Emond P, Okubo Y, Chou YH, Frangin Y, Douziech L, Gareau L, Swahn CG, Besnard JC, Farde L, Guilloteau D. PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter. Nuclear Medicine and Biology. 26: 491-9. PMID 10473187 DOI: 10.1016/S0969-8051(99)00004-9 |
0.464 |
|
| 1999 |
Gulyás B, Halldin C, Karlsson P, Chou YH, Swahn CG, Bönöczk P, Farde L. [Cerebral uptake and metabolism of (11C) Vinpocetine in monkeys: PET studies]. Orvosi Hetilap. 140: 1687-91. PMID 10461449 |
0.568 |
|
| 1999 |
Andrée B, Thorberg SO, Halldin C, Farde L. Pindolol binding to 5-HT1A receptors in the human brain confirmed with positron emission tomography. Psychopharmacology. 144: 303-5. PMID 10435400 DOI: 10.1007/S002130051009 |
0.468 |
|
| 1999 |
Lundkvist C, Halldin C, Swahn CG, Ginovart N, Farde L. Different brain radioactivity curves in a PET study with [11C]beta-CIT labelled in two different positions. Nuclear Medicine and Biology. 26: 343-50. PMID 10382835 DOI: 10.1016/S0969-8051(98)00111-5 |
0.342 |
|
| 1999 |
Nyberg S, Eriksson B, Oxenstierna G, Halldin C, Farde L. Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients. The American Journal of Psychiatry. 156: 869-75. PMID 10360125 DOI: 10.1176/Ajp.156.6.869 |
0.38 |
|
| 1999 |
Abi-Dargham A, Simpson N, Kegeles L, Parsey R, Hwang DR, Anjilvel S, Zea-Ponce Y, Lombardo I, Van Heertum R, Mann JJ, Foged C, Halldin C, Laruelle M. PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756. Synapse (New York, N.Y.). 32: 93-109. PMID 10231129 DOI: 10.1016/S1053-8119(18)31910-4 |
0.483 |
|
| 1999 |
Sandell J, Halldin C, Hall H, Thorberg SO, Werner T, Sohn D, Sedvall G, Farde L. Radiosynthesis and autoradiographic evaluation of [11C]NAD-299, a radioligand for visualization of the 5-HT1A receptor. Nuclear Medicine and Biology. 26: 159-64. PMID 10100214 DOI: 10.1016/S0969-8051(98)00091-2 |
0.49 |
|
| 1999 |
Ginovart N, Farde L, Halldin C, Swahn CG. Changes in striatal D2-receptor density following chronic treatment with amphetamine as assessed with PET in nonhuman primates. Synapse (New York, N.Y.). 31: 154-62. PMID 10024013 DOI: 10.1002/(Sici)1098-2396(199902)31:2<154::Aid-Syn9>3.0.Co;2-K |
0.413 |
|
| 1999 |
Ito H, Halldin C, Farde L. Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C]WAY-100635: PET with anatomic standardization technique. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 40: 102-9. PMID 9935065 |
0.389 |
|
| 1999 |
Ito H, Okubo Y, Halldin C, Farde L. Mapping of central D2 dopamine receptors in man using [11C]raclopride: PET with anatomic standardization technique. Neuroimage. 9: 235-42. PMID 9927552 DOI: 10.1006/Nimg.1998.0401 |
0.492 |
|
| 1999 |
Pauli S, Hall H, Halldin C, Hurd Y, Sedvall G. Spatial visualization and relative quantification of D2- dopamine receptors in a human post mortem brain hemisphere European Neuropsychopharmacology. 9: 355. DOI: 10.1016/S0924-977X(99)80537-9 |
0.396 |
|
| 1999 |
Langer O, Någren K, Dolle F, Lundkvist C, Sandell J, Swahn CG, Vaufrey F, Crouzel C, Maziere B, Halldin C. Precursor synthesis and radiolabelling of the dopamine D2 receptor ligand [11C]raclopride from [11C]methyl triflate Journal of Labelled Compounds and Radiopharmaceuticals. 42: 1183-1193. DOI: 10.1002/(SICI)1099-1344(199912)42:12<1183::AID-JLCR274>3.0.CO;2-Z |
0.303 |
|
| 1998 |
Nyberg S, Dencker SJ, Malm U, Dahl ML, Svenson JO, Halldin C, Naskashima Y, Farde L. D(2)- and 5-HT(2) receptor occupancy in high-dose neuroleptic-treated patients. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 1: 95-101. PMID 11281952 DOI: 10.1017/S1461145798001229 |
0.391 |
|
| 1998 |
Halldin C, Foged C, Chou YH, Karlsson P, Swahn CG, Sandell J, Sedvall G, Farde L. Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 39: 2061-8. PMID 9867142 |
0.431 |
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