Year |
Citation |
Score |
2020 |
da Silva Soley B, Silva LM, Mendes DAGB, Báfica A, Pesquero JB, Bader M, Witherden DA, Havran WL, Calixto JB, Otuki MF, Cabrini DA. B1 AND B2 KININ RECEPTOR BLOCKADE IMPROVES PSORIASIS-LIKE DISEASE. British Journal of Pharmacology. PMID 32335893 DOI: 10.1111/Bph.15077 |
0.311 |
|
2020 |
Gonçalves ECD, Vieira G, Gonçalves TR, Simões RR, Brusco I, Oliveira SM, Calixto JB, Cola M, Santos ARS, Dutra RC. Bradykinin Receptors Play a Critical Role in the Chronic Post-ischaemia Pain Model. Cellular and Molecular Neurobiology. PMID 32222846 DOI: 10.1007/S10571-020-00832-3 |
0.368 |
|
2019 |
Segat GC, Moreira CG, Santos EC, Heller M, Schwanke RC, Aksenov AV, Aksenov NA, Aksenov DA, Kornienko A, Marcon R, Calixto JB. A new series of acetohydroxamates shows in vitro and in vivo anticancer activity against melanoma. Investigational New Drugs. PMID 31493129 DOI: 10.1007/S10637-019-00849-6 |
0.31 |
|
2019 |
Pereira DMS, Teixeira SA, Murillo O, Peixoto EPM, Araújo MC, Sousa NCF, Monteiro-Neto V, Calixto JB, Cunha TM, Marinho CRF, Muscará MN, Fernandes ES. TRPV1 Contributes to Cerebral Malaria Severity and Mortality by Regulating Brain Inflammation. Oxidative Medicine and Cellular Longevity. 2019: 9451671. PMID 31223430 DOI: 10.1155/2019/9451671 |
0.308 |
|
2019 |
Manjavachi MN, Passos GF, Trevisan G, Araújo SB, Pontes JP, Fernandes ES, Costa R, Calixto JB. Spinal blockage of CXCL1 and its receptor CXCR2 inhibits paclitaxel-induced peripheral neuropathy in mice. Neuropharmacology. PMID 30991054 DOI: 10.1016/J.Neuropharm.2019.04.014 |
0.397 |
|
2019 |
Quintão NLM, Rocha LW, da Silva GF, Paszcuk AF, Manjavachi MN, Bento AF, da Silva KABS, Campos MM, Calixto JB. Correction to: The kinin B and B receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus. Inflammopharmacology. PMID 30955169 DOI: 10.1007/S10787-019-00590-9 |
0.315 |
|
2019 |
Quintão NLM, Rocha LW, da Silva GF, Paszcuk AF, Manjavachi MN, Bento AF, da Silva KABS, Campos MM, Calixto JB. The kinin B and B receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus. Inflammopharmacology. PMID 30820720 DOI: 10.1007/S10787-019-00578-5 |
0.42 |
|
2018 |
Pereira DMS, Mendes SJF, Alawi K, Thakore P, Aubdool A, Sousa NCF, da Silva JFR, Castro JA, P Pereira IC, Silva LCN, Grisotto MAG, Monteiro-Neto V, Costa SKP, da Costa R, Calixto JB, et al. Transient Receptor Potential Canonical Channels 4 and 5 Mediate -Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice. Oxidative Medicine and Cellular Longevity. 2018: 4904696. PMID 29983857 DOI: 10.1155/2018/4904696 |
0.359 |
|
2017 |
Soares DM, Santos DR, Rummel C, Ott D, Melo MCC, Roth J, Calixto JB, Souza GEP. The relevance of kalikrein-kinin system via activation of B2 receptor in LPS-induced fever in rats. Neuropharmacology. PMID 28826826 DOI: 10.1016/J.Neuropharm.2017.08.019 |
0.359 |
|
2017 |
Segat GC, Manjavachi MN, Matias DO, Passos GF, Freitas CS, Costa R, Calixto JB. Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice. Neuropharmacology. PMID 28729222 DOI: 10.1016/J.Neuropharm.2017.07.015 |
0.407 |
|
2017 |
Costa R, Bicca MA, Manjavachi MN, Segat GC, Dias FC, Fernandes ES, Calixto JB. Kinin Receptors Sensitize TRPV4 Channel and Induce Mechanical Hyperalgesia: Relevance to Paclitaxel-Induced Peripheral Neuropathy in Mice. Molecular Neurobiology. PMID 28283888 DOI: 10.1007/S12035-017-0475-9 |
0.424 |
|
2017 |
Rodrigues-Junior VS, Machado P, Calixto JB, Siqueira JM, Andrade E, Bento A, Campos MM, Basso LA, Santos DS. Preclinical safety evaluation of IQG-607 in rats: Acute and repeated dose toxicity studies. Regulatory Toxicology and Pharmacology : Rtp. 86: 11-17. PMID 28232042 DOI: 10.1016/J.Yrtph.2017.02.016 |
0.303 |
|
2016 |
Meotti FC, Figueiredo CP, Manjavachi M, Calixto JB. The transient receptor potential ankyrin-1 mediates mechanical hyperalgesia induced by the activation of B1 receptor in mice. Biochemical Pharmacology. PMID 27823962 DOI: 10.1016/J.Bcp.2016.11.003 |
0.37 |
|
2016 |
Claudino RF, Leite DF, Bento AF, Chichorro JG, Calixto JB, Rae GA. Potential role for ET-2 acting through ETA receptors in experimental colitis in mice. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 66: 141-155. PMID 27778057 DOI: 10.1007/S00011-016-1001-7 |
0.301 |
|
2016 |
Junqueira SC, Dos Santos Coelho I, Lieberknecht V, Cunha MP, Calixto JB, Rodrigues AL, Santos AR, Dutra RC. Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor. Molecular Neurobiology. PMID 27130268 DOI: 10.1007/S12035-016-9893-3 |
0.338 |
|
2015 |
da Silva MD, Cidral-Filho FJ, Winkelmann-Duarte EC, Cargnin-Ferreira E, Calixto JB, Dutra RC, Santos AR. Diacerein reduces joint damage, pain behavior and inhibits transient receptor potential vanilloid 1, matrix metalloproteinase and glial cells in rat spinal cord. International Journal of Rheumatic Diseases. PMID 26481104 DOI: 10.1111/1756-185X.12741 |
0.345 |
|
2015 |
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, et al. Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells. Chemmedchem. PMID 26434977 DOI: 10.1002/Cmdc.201500360 |
0.315 |
|
2015 |
Nguelefack TB, Dutra RC, Paszcuk AF, de Andrade EL, Calixto JB. TRPV1 channel inhibition contributes to the antinociceptive effects of Croton macrostachyus extract in mice. Bmc Complementary and Alternative Medicine. 15: 293. PMID 26303910 DOI: 10.1186/S12906-015-0816-Z |
0.388 |
|
2015 |
Assis DM, Juliano L, Paschoalin T, Kouyoumdjian M, Calixto JB, Santos RA, Pertinhez TA, Gauthier F, Moreau T, Blaber M, Juliano MA. Pharmacological Activities and Hydrolysis by Peptidases of [Phospho-Ser(6)]-Bradykinin (pS(6)-BK). Biochemical Pharmacology. 97: 203-14. PMID 26235942 DOI: 10.1016/J.Bcp.2015.07.033 |
0.322 |
|
2015 |
Luiz AP, Schroeder SD, Rae GA, Calixto JB, Chichorro JG. Contribution and interaction of kinin receptors and dynorphin A in a model of trigeminal neuropathic pain in mice. Neuroscience. 300: 189-200. PMID 25982562 DOI: 10.1016/J.Neuroscience.2015.05.015 |
0.389 |
|
2015 |
Patricio ES, Costa R, Figueiredo CP, Gers-Barlag K, Bicca MA, Manjavachi MN, Segat GC, Gentry C, Luiz AP, Fernandes ES, Cunha TM, Bevan S, Calixto JB. Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice. The Journal of Investigative Dermatology. 135: 2484-91. PMID 25955385 DOI: 10.1038/Jid.2015.183 |
0.374 |
|
2015 |
Loch-Neckel G, Bicca MA, Leal PC, Mascarello A, Siqueira JM, Calixto JB. In vitro and in vivo anti-glioma activity of a chalcone-quinoxaline hybrid. European Journal of Medicinal Chemistry. 90: 93-100. PMID 25461314 DOI: 10.1016/J.Ejmech.2014.11.014 |
0.341 |
|
2015 |
Bicca MA, Costa R, Loch-Neckel G, Figueiredo CP, Medeiros R, Calixto JB. B₂ receptor blockage prevents Aβ-induced cognitive impairment by neuroinflammation inhibition. Behavioural Brain Research. 278: 482-91. PMID 25446751 DOI: 10.1016/J.Bbr.2014.10.040 |
0.352 |
|
2015 |
Nascimento FP, Macedo-Júnior SJ, Pamplona FA, Luiz-Cerutti M, Córdova MM, Constantino L, Tasca CI, Dutra RC, Calixto JB, Reid A, Sawynok J, Santos AR. Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects. Molecular Neurobiology. 51: 1368-78. PMID 25064055 DOI: 10.1007/S12035-014-8815-5 |
0.361 |
|
2014 |
Meotti FC, Lemos de Andrade E, Calixto JB. TRP modulation by natural compounds. Handbook of Experimental Pharmacology. 223: 1177-238. PMID 24961985 DOI: 10.1007/978-3-319-05161-1_19 |
0.35 |
|
2014 |
Alberti TB, Marcon R, Bicca MA, Raposo NR, Calixto JB, Dutra RC. Essential oil from Pterodon emarginatus seeds ameliorates experimental autoimmune encephalomyelitis by modulating Th1/Treg cell balance. Journal of Ethnopharmacology. 155: 485-94. PMID 24892832 DOI: 10.1016/J.Jep.2014.05.044 |
0.346 |
|
2014 |
Rosa F, Trevisan G, Rigo FK, Tonello R, Andrade EL, Cordeiro Mdo N, Calixto JB, Gomez MV, Ferreira J. Phα1β, a peptide from the venom of the spider Phoneutria nigriventer shows antinociceptive effects after continuous infusion in a neuropathic pain model in rats. Anesthesia and Analgesia. 119: 196-202. PMID 24836473 DOI: 10.1213/Ane.0000000000000249 |
0.317 |
|
2014 |
Manjavachi MN, Costa R, Quintão NL, Calixto JB. The role of keratinocyte-derived chemokine (KC) on hyperalgesia caused by peripheral nerve injury in mice. Neuropharmacology. 79: 17-27. PMID 24184386 DOI: 10.1016/J.Neuropharm.2013.10.026 |
0.364 |
|
2014 |
Dornelles FN, Andrade EL, Campos MM, Calixto JB. Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis. British Journal of Pharmacology. 171: 452-67. PMID 24117268 DOI: 10.1111/Bph.12467 |
0.387 |
|
2014 |
Fernandes ES, Medeiros R, Campos MM, Calixto JB. PAF-induced kinin B1 receptor in vivo up-regulation: involvement of distinct kinase pathways Inflammation Research. 56: S488-S491. DOI: 10.1007/Bf03353886 |
0.343 |
|
2013 |
Maciel IS, Silva RB, Morrone FB, Calixto JB, Campos MM. Synergistic effects of celecoxib and bupropion in a model of chronic inflammation-related depression in mice. Plos One. 8: e77227. PMID 24086771 DOI: 10.1371/Journal.Pone.0077227 |
0.337 |
|
2013 |
Marcon R, Bento AF, Dutra RC, Bicca MA, Leite DF, Calixto JB. Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis. Journal of Immunology (Baltimore, Md. : 1950). 191: 4288-98. PMID 24038091 DOI: 10.4049/Jimmunol.1202743 |
0.334 |
|
2013 |
Schwanke RC, Marcon R, Meotti FC, Bento AF, Dutra RC, Pizzollatti MG, Calixto JB. Oral administration of the flavonoid myricitrin prevents dextran sulfate sodium-induced experimental colitis in mice through modulation of PI3K/Akt signaling pathway. Molecular Nutrition & Food Research. 57: 1938-49. PMID 23861337 DOI: 10.1002/Mnfr.201300134 |
0.338 |
|
2013 |
Trevisan G, Rossato MF, Walker CI, Oliveira SM, Rosa F, Tonello R, Silva CR, Machado P, Boligon AA, Martins MA, Zanatta N, Bonacorso HG, Athayde ML, Rubin MA, Calixto JB, et al. A novel, potent, oral active and safe antinociceptive pyrazole targeting kappa opioid receptors. Neuropharmacology. 73: 261-73. PMID 23791558 DOI: 10.1016/J.Neuropharm.2013.06.011 |
0.39 |
|
2013 |
Meotti FC, Forner S, Lima-Garcia JF, Viana AF, Calixto JB. Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis. Chemico-Biological Interactions. 203: 440-7. PMID 23523557 DOI: 10.1016/J.Cbi.2013.03.008 |
0.387 |
|
2013 |
Matos I, Bento AF, Marcon R, Claudino RF, Calixto JB. Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: the relevance of cannabinoid system. Molecular Immunology. 54: 482-92. PMID 23454360 DOI: 10.1016/J.Molimm.2013.01.018 |
0.307 |
|
2013 |
Dutra RC, Bento AF, Leite DF, Manjavachi MN, Marcon R, Bicca MA, Pesquero JB, Calixto JB. The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: evidence for the involvement of astrocytes. Neurobiology of Disease. 54: 82-93. PMID 23454198 DOI: 10.1016/J.Nbd.2013.02.007 |
0.356 |
|
2013 |
Passos GF, Medeiros R, Marcon R, Nascimento AF, Calixto JB, Pianowski LF. The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice. European Journal of Pharmacology. 698: 413-20. PMID 23099255 DOI: 10.1016/J.Ejphar.2012.10.019 |
0.361 |
|
2013 |
Couto AG, Kassuya CAL, Calixto JB, Petrovick PR. Anti-inflammatory, antiallodynic effects and quantitative analysis of gallic acid in spray dried powders from Phyllanthus niruri leaves, stems, roots and whole plant Brazilian Journal of Pharmacognosy. 23: 124-131. DOI: 10.1590/S0102-695X2012005000133 |
0.328 |
|
2012 |
Pamplona FA, Ferreira J, Menezes de Lima O, Duarte FS, Bento AF, Forner S, Villarinho JG, Bellocchio L, Bellochio L, Wotjak CT, Lerner R, Monory K, Lutz B, Canetti C, Matias I, ... Calixto JB, et al. Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 21134-9. PMID 23150578 DOI: 10.1073/Pnas.1202906109 |
0.361 |
|
2012 |
Bento AF, Leite DF, Marcon R, Claudino RF, Dutra RC, Cola M, Martini AC, Calixto JB. Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice. Biochemical Pharmacology. 84: 1459-69. PMID 23000912 DOI: 10.1016/J.Bcp.2012.09.007 |
0.334 |
|
2012 |
Basei FL, Cabrini DA, Figueiredo CP, Forner S, Hara DB, Nascimento AF, Ceravolo GS, Carvalho MH, Bader M, Medeiros R, Calixto JB. Endothelium dependent expression and underlying mechanisms of des-Argâ¹-bradykinin-induced Bâ‚R-mediated vasoconstriction in rat portal vein. Peptides. 37: 216-24. PMID 22868213 DOI: 10.1016/J.Peptides.2012.07.020 |
0.332 |
|
2012 |
Forner S, Andrade EL, Martini AC, Bento AF, Medeiros R, Koepp J, Calixto JB. Effects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats. British Journal of Pharmacology. 167: 1737-52. PMID 22862305 DOI: 10.1111/J.1476-5381.2012.02127.X |
0.321 |
|
2012 |
Costa R, Motta EM, Manjavachi MN, Cola M, Calixto JB. Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice. Neuropharmacology. 63: 798-805. PMID 22722030 DOI: 10.1016/J.Neuropharm.2012.06.004 |
0.372 |
|
2012 |
Dutra RC, Simão da Silva KA, Bento AF, Marcon R, Paszcuk AF, Meotti FC, Pianowski LF, Calixto JB. Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system. Neuropharmacology. 63: 593-605. PMID 22613837 DOI: 10.1016/J.Neuropharm.2012.05.008 |
0.379 |
|
2012 |
Dutra RC, de Souza PR, Bento AF, Marcon R, Bicca MA, Pianowski LF, Calixto JB. Euphol prevents experimental autoimmune encephalomyelitis in mice: evidence for the underlying mechanisms. Biochemical Pharmacology. 83: 531-42. PMID 22155310 DOI: 10.1016/J.Bcp.2011.11.026 |
0.345 |
|
2012 |
Andrade EL, Meotti FC, Calixto JB. TRPA1 antagonists as potential analgesic drugs. Pharmacology & Therapeutics. 133: 189-204. PMID 22119554 DOI: 10.1016/J.Pharmthera.2011.10.008 |
0.327 |
|
2012 |
Braganhol E, Zanin RF, Bernardi A, Bergamin LS, Cappellari AR, Campesato LF, Morrone FB, Campos MM, Calixto JB, Edelweiss MI, Wink MR, Sévigny J, Robson SC, Battastini AM. Overexpression of NTPDase2 in gliomas promotes systemic inflammation and pulmonary injury. Purinergic Signalling. 8: 235-43. PMID 22038661 DOI: 10.1007/S11302-011-9276-1 |
0.312 |
|
2012 |
da Silva KA, Manjavachi MN, Paszcuk AF, Pivatto M, Viegas C, Bolzani VS, Calixto JB. Plant derived alkaloid (-)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models. Neuropharmacology. 62: 967-77. PMID 22032869 DOI: 10.1016/J.Neuropharm.2011.10.002 |
0.407 |
|
2012 |
Kaster MP, Gadotti VM, Calixto JB, Santos AR, Rodrigues AL. Depressive-like behavior induced by tumor necrosis factor-α in mice. Neuropharmacology. 62: 419-26. PMID 21867719 DOI: 10.1016/J.Neuropharm.2011.08.018 |
0.32 |
|
2012 |
Romanini J, Mielcke TR, Leal PC, Figueiredo CP, Calixto JB, Morrone FB, Batista EL, Campos MM. The role of CXCR2 chemokine receptors in the oral squamous cell carcinoma. Investigational New Drugs. 30: 1371-8. PMID 21670971 DOI: 10.1007/S10637-011-9701-X |
0.348 |
|
2011 |
Dutra RC, Leite DF, Bento AF, Manjavachi MN, PatrÃcio ES, Figueiredo CP, Pesquero JB, Calixto JB. The role of kinin receptors in preventing neuroinflammation and its clinical severity during experimental autoimmune encephalomyelitis in mice. Plos One. 6: e27875. PMID 22132157 DOI: 10.1371/Journal.Pone.0027875 |
0.335 |
|
2011 |
Paszcuk AF, Dutra RC, da Silva KA, Quintão NL, Campos MM, Calixto JB. Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases. Plos One. 6: e24034. PMID 21931637 DOI: 10.1371/Journal.Pone.0024034 |
0.33 |
|
2011 |
Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, Campos MM, Morrone FB. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn-Schmiedeberg's Archives of Pharmacology. 384: 265-75. PMID 21789632 DOI: 10.1007/S00210-011-0668-0 |
0.377 |
|
2011 |
Bento AF, Claudino RF, Dutra RC, Marcon R, Calixto JB. Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice. Journal of Immunology (Baltimore, Md. : 1950). 187: 1957-69. PMID 21724996 DOI: 10.4049/Jimmunol.1101305 |
0.34 |
|
2011 |
Guerra GP, Mello CF, Bochi GV, Pazini AM, Fachinetto R, Dutra RC, Calixto JB, Ferreira J, Rubin MA. Hippocampal PKA/CREB pathway is involved in the improvement of memory induced by spermidine in rats. Neurobiology of Learning and Memory. 96: 324-32. PMID 21708277 DOI: 10.1016/J.Nlm.2011.06.007 |
0.322 |
|
2011 |
Rogerio AP, Andrade EL, Calixto JB. C-fibers, but not the transient potential receptor vanilloid 1 (TRPV1), play a role in experimental allergic airway inflammation. European Journal of Pharmacology. 662: 55-62. PMID 21539840 DOI: 10.1016/J.Ejphar.2011.04.027 |
0.336 |
|
2011 |
Costa R, Motta EM, Dutra RC, Manjavachi MN, Bento AF, Malinsky FR, Pesquero JB, Calixto JB. Anti-nociceptive effect of kinin Bâ‚ and Bâ‚‚ receptor antagonists on peripheral neuropathy induced by paclitaxel in mice. British Journal of Pharmacology. 164: 681-93. PMID 21470206 DOI: 10.1111/J.1476-5381.2011.01408.X |
0.391 |
|
2011 |
Lima-Garcia JF, Dutra RC, da Silva K, Motta EM, Campos MM, Calixto JB. The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats. British Journal of Pharmacology. 164: 278-93. PMID 21418187 DOI: 10.1111/J.1476-5381.2011.01345.X |
0.345 |
|
2011 |
Andrade EL, Forner S, Bento AF, Leite DF, Dias MA, Leal PC, Koepp J, Calixto JB. TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury. American Journal of Physiology. Renal Physiology. 300: F1223-34. PMID 21367919 DOI: 10.1152/Ajprenal.00535.2010 |
0.31 |
|
2011 |
Bento AF, Marcon R, Dutra RC, Claudino RF, Cola M, Leite DF, Calixto JB. β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway. The American Journal of Pathology. 178: 1153-66. PMID 21356367 DOI: 10.1016/J.Ajpath.2010.11.052 |
0.397 |
|
2011 |
Figueiredo CP, Bicca MA, Latini A, Prediger RD, Medeiros R, Calixto JB. Folic acid plus α-tocopherol mitigates amyloid-β-induced neurotoxicity through modulation of mitochondrial complexes activity. Journal of Alzheimer's Disease : Jad. 24: 61-75. PMID 21157027 DOI: 10.3233/Jad-2010-101320 |
0.301 |
|
2011 |
Viana AF, Maciel IS, Motta EM, Leal PC, Pianowski L, Campos MM, Calixto JB. Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects. Evidence-Based Complementary and Alternative Medicine : Ecam. 2011: 120820. PMID 19815648 DOI: 10.1093/Ecam/Nep144 |
0.349 |
|
2011 |
Dutra R, Silva K, Bento A, Paszcuk A, Marcon R, Meiotti F, Motta E, Pianowski L, Calixto J. Euphol, a novel cannabinoid agonist, prevents inflammatory and neuropathic persistent pain in rodents Planta Medica. 77. DOI: 10.1055/S-0031-1282169 |
0.315 |
|
2010 |
Viana AF, Maciel IS, Dornelles FN, Figueiredo CP, Siqueira JM, Campos MM, Calixto JB. Kinin B1 receptors mediate depression-like behavior response in stressed mice treated with systemic E. coli lipopolysaccharide. Journal of Neuroinflammation. 7: 98. PMID 21194425 DOI: 10.1186/1742-2094-7-98 |
0.357 |
|
2010 |
Santos AA, Leal PC, Edelweiss MI, Lopes TG, Calixto JB, Morrone FB, Campos MM. Effects of the compounds MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 382: 399-407. PMID 20809237 DOI: 10.1007/S00210-010-0555-0 |
0.403 |
|
2010 |
Manjavachi MN, Motta EM, Marotta DM, Leite DF, Calixto JB. Mechanisms involved in IL-6-induced muscular mechanical hyperalgesia in mice. Pain. 151: 345-55. PMID 20709454 DOI: 10.1016/J.Pain.2010.07.018 |
0.336 |
|
2010 |
Nguelefack TB, Dutra RC, Paszcuk AF, Andrade EL, Tapondjou LA, Calixto JB. Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation. Journal of Ethnopharmacology. 128: 567-74. PMID 20152893 DOI: 10.1016/J.Jep.2010.01.061 |
0.403 |
|
2010 |
Medeiros R, Figueiredo CP, Pandolfo P, Duarte FS, Prediger RD, Passos GF, Calixto JB. The role of TNF-alpha signaling pathway on COX-2 upregulation and cognitive decline induced by beta-amyloid peptide. Behavioural Brain Research. 209: 165-73. PMID 20122965 DOI: 10.1016/J.Bbr.2010.01.040 |
0.315 |
|
2010 |
Costa R, Manjavachi MN, Motta EM, Marotta DM, Juliano L, Torres HA, Pesquero JB, Calixto JB. The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice. British Journal of Pharmacology. 159: 888-97. PMID 20067469 DOI: 10.1111/J.1476-5381.2009.00571.X |
0.364 |
|
2010 |
da Costa DS, Meotti FC, Andrade EL, Leal PC, Motta EM, Calixto JB. The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation. Pain. 148: 431-7. PMID 20056530 DOI: 10.1016/J.Pain.2009.12.002 |
0.406 |
|
2010 |
Luiz AP, Schroeder SD, Chichorro JG, Calixto JB, Zampronio AR, Rae GA. Kinin B(1) and B(2) receptors contribute to orofacial heat hyperalgesia induced by infraorbital nerve constriction injury in mice and rats. Neuropeptides. 44: 87-92. PMID 19914714 DOI: 10.1016/J.Npep.2009.10.005 |
0.373 |
|
2010 |
Rogerio AP, Dora CL, Andrade EL, Chaves JS, Silva LF, Lemos-Senna E, Calixto JB. Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 61: 288-97. PMID 19892018 DOI: 10.1016/J.Phrs.2009.10.005 |
0.366 |
|
2010 |
Manjavachi MN, Quintão NL, Campos MM, Deschamps IK, Yunes RA, Nunes RJ, Leal PC, Calixto JB. The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice. European Journal of Pain (London, England). 14: 23-31. PMID 19264522 DOI: 10.1016/J.Ejpain.2009.01.007 |
0.415 |
|
2010 |
Bicca MA, Figueiredo CP, Passos GF, Joaquim YA, Meotti FC, Prediger RD, Medeiros R, Calixto JB. P2-336: Cognitive impairment induced by beta-amyloid peptide in mice depends on the NMDA receptor activation and nNOS up-regulation Alzheimer's & Dementia. 6: S412-S412. DOI: 10.1016/J.Jalz.2010.05.1387 |
0.304 |
|
2009 |
Passos GF, Figueiredo CP, Prediger RD, Pandolfo P, Duarte FS, Medeiros R, Calixto JB. Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide. The American Journal of Pathology. 175: 1586-97. PMID 19729478 DOI: 10.2353/Ajpath.2009.081113 |
0.343 |
|
2009 |
Dornelles FN, Santos DS, Van Dyke TE, Calixto JB, Batista EL, Campos MM. In vivo up-regulation of kinin B1 receptors after treatment with Porphyromonas gingivalis lipopolysaccharide in rat paw. The Journal of Pharmacology and Experimental Therapeutics. 330: 756-63. PMID 19561153 DOI: 10.1124/Jpet.109.155762 |
0.384 |
|
2009 |
Fogo AS, Antonioli E, Calixto JB, Campos AH. Tormentic acid reduces vascular smooth muscle cell proliferation and survival. European Journal of Pharmacology. 615: 50-4. PMID 19464287 DOI: 10.1016/J.Ejphar.2009.05.009 |
0.308 |
|
2009 |
Rogerio AP, Andrade EL, Leite DF, Figueiredo CP, Calixto JB. Preventive and therapeutic anti-inflammatory properties of the sesquiterpene alpha-humulene in experimental airways allergic inflammation. British Journal of Pharmacology. 158: 1074-87. PMID 19438512 DOI: 10.1111/J.1476-5381.2009.00177.X |
0.345 |
|
2009 |
Bernardi A, Zilberstein AC, Jäger E, Campos MM, Morrone FB, Calixto JB, Pohlmann AR, Guterres SS, Battastini AM. Effects of indomethacin-loaded nanocapsules in experimental models of inflammation in rats. British Journal of Pharmacology. 158: 1104-11. PMID 19422380 DOI: 10.1111/J.1476-5381.2009.00244.X |
0.339 |
|
2009 |
Medeiros R, Figueiredo CP, Passos GF, Calixto JB. Reduced skin inflammatory response in mice lacking inducible nitric oxide synthase. Biochemical Pharmacology. 78: 390-5. PMID 19409374 DOI: 10.1016/J.Bcp.2009.04.021 |
0.344 |
|
2009 |
Guginski G, Luiz AP, Silva MD, Massaro M, Martins DF, Chaves J, Mattos RW, Silveira D, Ferreira VM, Calixto JB, Santos AR. Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. Pharmacology, Biochemistry, and Behavior. 93: 10-6. PMID 19358864 DOI: 10.1016/J.Pbb.2009.03.014 |
0.378 |
|
2009 |
Marotta DM, Costa R, Motta EM, Fernandes ES, Medeiros R, Quintão NL, Campos MM, Calixto JB. Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw. Biochemical Pharmacology. 77: 1223-35. PMID 19283893 DOI: 10.1016/J.Bcp.2008.12.025 |
0.434 |
|
2009 |
Oliveira MS, Furian AF, Rambo LM, Ribeiro LR, Royes LF, Ferreira J, Calixto JB, Otalora LF, Garrido-Sanabria ER, Mello CF. Prostaglandin E2 modulates Na+,K+-ATPase activity in rat hippocampus: implications for neurological diseases. Journal of Neurochemistry. 109: 416-26. PMID 19200345 DOI: 10.1111/J.1471-4159.2009.05961.X |
0.302 |
|
2009 |
Pereira PJS, Dornelles FN, Santos DS, Calixto JB, Morrone FB, Campos MM. Nociceptive and inflammatory responses induced by formalin in the orofacial region of rats: Effect of anti-TNFα strategies International Immunopharmacology. 9: 80-85. PMID 18957334 DOI: 10.1016/J.Intimp.2008.10.001 |
0.37 |
|
2008 |
Chaves JS, Leal PC, Pianowisky L, Calixto JB. Pharmacokinetics and tissue distribution of the sesquiterpene alpha-humulene in mice. Planta Medica. 74: 1678-83. PMID 18951339 DOI: 10.1055/S-0028-1088307 |
0.309 |
|
2008 |
Bento AF, Leite DF, Claudino RF, Hara DB, Leal PC, Calixto JB. The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice. Journal of Leukocyte Biology. 84: 1213-21. PMID 18653784 DOI: 10.1189/Jlb.0408231 |
0.361 |
|
2008 |
Kassuya CA, Rogerio AP, Calixto JB. The role of ET(A) and ET(B) receptor antagonists in acute and allergic inflammation in mice. Peptides. 29: 1329-37. PMID 18632188 DOI: 10.1016/J.Peptides.2008.03.008 |
0.356 |
|
2008 |
Royes LF, Fighera MR, Furian AF, Oliveira MS, Fiorenza NG, Ferreira J, da Silva AC, Priel MR, Ueda ES, Calixto JB, Cavalheiro EA, Mello CF. Neuromodulatory effect of creatine on extracellular action potentials in rat hippocampus: role of NMDA receptors. Neurochemistry International. 53: 33-7. PMID 18541342 DOI: 10.1016/J.Neuint.2008.04.008 |
0.347 |
|
2008 |
Costa R, Marotta DM, Manjavachi MN, Fernandes ES, Lima-Garcia JF, Paszcuk AF, Quintão NL, Juliano L, Brain SD, Calixto JB. Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice. British Journal of Pharmacology. 154: 1094-103. PMID 18454165 DOI: 10.1038/Bjp.2008.172 |
0.315 |
|
2008 |
Medeiros R, Rodrigues GB, Figueiredo CP, Rodrigues EB, Grumman A, Menezes-de-Lima O, Passos GF, Calixto JB. Molecular mechanisms of topical anti-inflammatory effects of lipoxin A(4) in endotoxin-induced uveitis. Molecular Pharmacology. 74: 154-61. PMID 18413658 DOI: 10.1124/Mol.108.046870 |
0.34 |
|
2008 |
Quintão NL, Passos GF, Medeiros R, Paszcuk AF, Motta FL, Pesquero JB, Campos MM, Calixto JB. Neuropathic pain-like behavior after brachial plexus avulsion in mice: the relevance of kinin B1 and B2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2856-63. PMID 18337416 DOI: 10.1523/Jneurosci.4389-07.2008 |
0.365 |
|
2008 |
Oliveira MS, Furian AF, Rambo LM, Ribeiro LR, Royes LF, Ferreira J, Calixto JB, Mello CF. Modulation of pentylenetetrazol-induced seizures by prostaglandin E2 receptors. Neuroscience. 152: 1110-8. PMID 18329178 DOI: 10.1016/J.Neuroscience.2008.01.005 |
0.302 |
|
2008 |
Andrade EL, Luiz AP, Ferreira J, Calixto JB. Pronociceptive response elicited by TRPA1 receptor activation in mice. Neuroscience. 152: 511-20. PMID 18272293 DOI: 10.1016/J.Neuroscience.2007.12.039 |
0.4 |
|
2008 |
Prediger RD, Medeiros R, Pandolfo P, Duarte FS, Passos GF, Pesquero JB, Campos MM, Calixto JB, Takahashi RN. Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer's disease. Neuroscience. 151: 631-43. PMID 18191900 DOI: 10.1016/J.Neuroscience.2007.11.009 |
0.34 |
|
2008 |
Andre E, Gazzieri D, Bardella E, Ferreira J, Mori MA, Saul VV, Bader M, Calixto JB, De Giorgio R, Corinaldesi R, Geppetti P, Trevisani M. Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder. Gut. 57: 628-33. PMID 18182589 DOI: 10.1136/Gut.2006.103200 |
0.366 |
|
2008 |
Ferreira J, Trichês KM, Medeiros R, Cabrini DA, Mori MA, Pesquero JB, Bader M, Calixto JB. The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice. Neuropharmacology. 54: 597-604. PMID 18164734 DOI: 10.1016/J.Neuropharm.2007.11.008 |
0.418 |
|
2008 |
Paszcuk AF, Quintão NL, Fernandes ES, Juliano L, Chapman K, Andrade-Gordon P, Campos MM, Vergnolle N, Calixto JB. Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw. European Journal of Pharmacology. 581: 204-15. PMID 18083162 DOI: 10.1016/J.Ejphar.2007.11.025 |
0.417 |
|
2008 |
Chiaradia LD, dos Santos R, Vitor CE, Vieira AA, Leal PC, Nunes RJ, Calixto JB, Yunes RA. Synthesis and pharmacological activity of chalcones derived from 2,4,6-trimethoxyacetophenone in RAW 264.7 cells stimulated by LPS: quantitative structure-activity relationships. Bioorganic & Medicinal Chemistry. 16: 658-67. PMID 17988874 DOI: 10.1016/J.Bmc.2007.10.039 |
0.345 |
|
2008 |
Quintão NL, Santos AR, Campos MM, Calixto JB. The role of neurotrophic factors in genesis and maintenance of mechanical hypernociception after brachial plexus avulsion in mice. Pain. 136: 125-33. PMID 17706869 DOI: 10.1016/J.Pain.2007.06.027 |
0.302 |
|
2007 |
Andrade EL, Ferreira J, Santos AR, Calixto JB. Pharmacological analysis of paregoric elixir and its constituents: in vitro and in vivo studies. Journal of Ethnopharmacology. 114: 218-26. PMID 17869462 DOI: 10.1016/J.Jep.2007.08.004 |
0.346 |
|
2007 |
Fachinetto R, Villarinho JG, Wagner C, Pereira RP, Avila DS, Burger ME, Calixto JB, Rocha JB, Ferreira J. Valeriana officinalis does not alter the orofacial dyskinesia induced by haloperidol in rats: role of dopamine transporter. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1478-86. PMID 17669571 DOI: 10.1016/J.Pnpbp.2007.06.028 |
0.318 |
|
2007 |
Fachinetto R, Villarinho JG, Wagner C, Pereira RP, Puntel RL, Paixão MW, Braga AL, Calixto JB, Rocha JB, Ferreira J. Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats. Psychopharmacology. 194: 423-32. PMID 17641876 DOI: 10.1007/S00213-007-0831-Y |
0.308 |
|
2007 |
Martini LH, Jung F, Soares FA, Rotta LN, Vendite DA, Frizzo ME, Yunes RA, Calixto JB, Wofchuk S, Souza DO. Naturally occurring compounds affect glutamatergic neurotransmission in rat brain. Neurochemical Research. 32: 1950-6. PMID 17577666 DOI: 10.1007/S11064-007-9393-Y |
0.301 |
|
2007 |
Leite DF, Echevarria-Lima J, Ferreira SC, Calixto JB, Rumjanek VM. ABCC transporter inhibition reduces zymosan-induced peritonitis. Journal of Leukocyte Biology. 82: 630-7. PMID 17576824 DOI: 10.1189/Jlb.0107042 |
0.374 |
|
2007 |
Paszcuk AF, Gadotti VM, Tibola D, Quintão NL, Rodrigues AL, Calixto JB, Santos AR. Anti-hypernociceptive properties of agmatine in persistent inflammatory and neuropathic models of pain in mice. Brain Research. 1159: 124-33. PMID 17573052 DOI: 10.1016/J.Brainres.2007.04.050 |
0.414 |
|
2007 |
Fernandes ES, Passos GF, Medeiros R, da Cunha FM, Ferreira J, Campos MM, Pianowski LF, Calixto JB. Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea. European Journal of Pharmacology. 569: 228-36. PMID 17559833 DOI: 10.1016/J.Ejphar.2007.04.059 |
0.371 |
|
2007 |
Werner MF, Kassuya CA, Ferreira J, Zampronio AR, Calixto JB, Rae GA. Peripheral kinin B(1) and B(2) receptor-operated mechanisms are implicated in neuropathic nociception induced by spinal nerve ligation in rats. Neuropharmacology. 53: 48-57. PMID 17555775 DOI: 10.1016/J.Neuropharm.2007.04.013 |
0.37 |
|
2007 |
Rogerio AP, Cardoso CR, Fontanari C, Souza MA, Afonso-Cardoso SR, Silva EV, Koyama NS, Basei FL, Soares EG, Calixto JB, Stowell SR, Dias-Baruffi M, Faccioli LH. Anti-asthmatic potential of a D-galactose-binding lectin from Synadenium carinatum latex. Glycobiology. 17: 795-804. PMID 17522108 DOI: 10.1093/Glycob/Cwm053 |
0.346 |
|
2007 |
Medeiros R, Passos GF, Vitor CE, Koepp J, Mazzuco TL, Pianowski LF, Campos MM, Calixto JB. Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw. British Journal of Pharmacology. 151: 618-27. PMID 17471174 DOI: 10.1038/Sj.Bjp.0707270 |
0.333 |
|
2007 |
Dalmolin GD, Silva CR, Bellé NA, Rubin MA, Mello CF, Calixto JB, Ferreira J. Bradykinin into amygdala induces thermal hyperalgesia in rats. Neuropeptides. 41: 263-70. PMID 17400291 DOI: 10.1016/J.Npep.2006.12.007 |
0.396 |
|
2007 |
Hara DB, Fernandes ES, Campos MM, Calixto JB. Pharmacological and biochemical characterization of bradykinin B2 receptors in the mouse colon: influence of the TNBS-induced colitis. Regulatory Peptides. 141: 25-34. PMID 17276525 DOI: 10.1016/J.Regpep.2006.12.013 |
0.402 |
|
2007 |
Duarte CD, Tributino JL, Lacerda DI, Martins MV, Alexandre-Moreira MS, Dutra F, Bechara EJ, De-Paula FS, Goulart MO, Ferreira J, Calixto JB, Nunes MP, Bertho AL, Miranda AL, Barreiro EJ, et al. Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. Bioorganic & Medicinal Chemistry. 15: 2421-33. PMID 17275312 DOI: 10.1016/J.Bmc.2007.01.013 |
0.352 |
|
2007 |
Medeiros R, Otuki MF, Avellar MC, Calixto JB. Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate. European Journal of Pharmacology. 559: 227-35. PMID 17258194 DOI: 10.1016/J.Ejphar.2006.12.005 |
0.358 |
|
2007 |
Rodrigues GB, Passos GF, Di Giunta G, Figueiredo CP, Rodrigues EB, Grumman A, Medeiros R, Calixto JB. Preventive and therapeutic anti-inflammatory effects of systemic and topical thalidomide on endotoxin-induced uveitis in rats. Experimental Eye Research. 84: 553-60. PMID 17223105 DOI: 10.1016/J.Exer.2006.11.009 |
0.374 |
|
2007 |
Leite DF, Echevarria-Lima J, Calixto JB, Rumjanek VM. Multidrug resistance related protein (ABCC1) and its role on nitrite production by the murine macrophage cell line RAW 264.7. Biochemical Pharmacology. 73: 665-74. PMID 17169333 DOI: 10.1016/J.Bcp.2006.11.005 |
0.331 |
|
2007 |
Passos GF, Fernandes ES, da Cunha FM, Ferreira J, Pianowski LF, Campos MM, Calixto JB. Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea. Journal of Ethnopharmacology. 110: 323-33. PMID 17084568 DOI: 10.1016/J.Jep.2006.09.032 |
0.346 |
|
2007 |
Goulart YCF, Martins JVC, Santos AR, Moreira LY, Calixto JB, Cortez DAG, Audi EA. Involvement of serotonin in the antidepressant-like effect of extract from Kielmeyera coriacea stems Pharmaceutical Biology. 45: 169-175. DOI: 10.1080/13880200701212981 |
0.331 |
|
2006 |
Campos MM, Leal PC, Yunes RA, Calixto JB. Non-peptide antagonists for kinin B1 receptors: new insights into their therapeutic potential for the management of inflammation and pain. Trends in Pharmacological Sciences. 27: 646-51. PMID 17056130 DOI: 10.1016/J.Tips.2006.10.007 |
0.35 |
|
2006 |
Veiga Junior VF, Zunino L, Patitucci ML, Pinto AC, Calixto JB. The inhibition of paw oedema formation caused by the oil of Copaifera multijuga Hayne and its fractions. The Journal of Pharmacy and Pharmacology. 58: 1405-10. PMID 17034665 DOI: 10.1111/J.2042-7158.2006.Tb01659.X |
0.308 |
|
2006 |
Mantovani M, Kaster MP, Pertile R, Calixto JB, Rodrigues AL, Santos AR. Mechanisms involved in the antinociception caused by melatonin in mice. Journal of Pineal Research. 41: 382-9. PMID 17014696 DOI: 10.1111/J.1600-079X.2006.00380.X |
0.393 |
|
2006 |
Menezes-de-Lima O, Kassuya CA, Nascimento AF, Henriques Md, Calixto JB. Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin. Prostaglandins & Other Lipid Mediators. 80: 123-35. PMID 16939877 DOI: 10.1016/J.Prostaglandins.2006.05.016 |
0.426 |
|
2006 |
Kassuya CA, Silvestre A, Menezes-de-Lima O, Marotta DM, Rehder VL, Calixto JB. Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor. European Journal of Pharmacology. 546: 182-8. PMID 16925995 DOI: 10.1016/J.Ejphar.2006.07.025 |
0.428 |
|
2006 |
Costa R, Fernandes ES, Menezes-de-Lima O, Campos MM, Calixto JB. Effect of novel selective non-peptide kinin B(1) receptor antagonists on mouse pleurisy induced by carrageenan. Peptides. 27: 2967-75. PMID 16914229 DOI: 10.1016/J.Peptides.2006.07.007 |
0.38 |
|
2006 |
Gadotti VM, Tibola D, Paszcuk AF, Rodrigues AL, Calixto JB, Santos AR. Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice. Brain Research. 1093: 116-22. PMID 16765330 DOI: 10.1016/J.Brainres.2006.03.087 |
0.383 |
|
2006 |
Mattos WM, Campos MM, Fernandes ES, Richetti GP, Niero R, Yunes RA, Calixto JB. Anti-edematogenic effects of velutinol A isolated from Mandevilla velutina: evidence for a selective inhibition of kinin B1 receptor-mediated responses. Regulatory Peptides. 136: 98-104. PMID 16764951 DOI: 10.1016/J.Regpep.2006.04.011 |
0.458 |
|
2006 |
Motta EM, Calixto JB, Rae GA. Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases. Experimental Biology and Medicine (Maywood, N.J.). 231: 1141-5. PMID 16741065 DOI: 10.3181/00379727-232-2311141 |
0.347 |
|
2006 |
Martini LH, Cereser L, Junior IZ, Jardim FM, Vendite DA, Frizzo ME, Yunes RA, Calixto JB, Wofchuk S, Souza DO. The sesquiterpenes polygodial and drimanial in vitro affect glutamatergic transport in rat brain. Neurochemical Research. 31: 431-8. PMID 16733820 DOI: 10.1007/S11064-005-9033-3 |
0.315 |
|
2006 |
Andrade EL, Ferreira J, André E, Calixto JB. Contractile mechanisms coupled to TRPA1 receptor activation in rat urinary bladder. Biochemical Pharmacology. 72: 104-14. PMID 16725114 DOI: 10.1016/J.Bcp.2006.04.003 |
0.403 |
|
2006 |
Rocha AC, Fernandes ES, Quintão NL, Campos MM, Calixto JB. Relevance of tumour necrosis factor-alpha for the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw. British Journal of Pharmacology. 148: 688-95. PMID 16702985 DOI: 10.1038/Sj.Bjp.0706775 |
0.376 |
|
2006 |
Claudino RF, Kassuya CA, Ferreira J, Calixto JB. Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema. The Journal of Pharmacology and Experimental Therapeutics. 318: 611-8. PMID 16644903 DOI: 10.1124/Jpet.106.102806 |
0.418 |
|
2006 |
Mattos WM, Ferreira J, Richetti GP, Niero R, Yunes RA, Calixto JB. Antinociceptive properties produced by the pregnane compound velutinol A isolated from Mandevilla velutina. Neuropeptides. 40: 125-32. PMID 16494941 DOI: 10.1016/J.Npep.2005.12.001 |
0.462 |
|
2006 |
El Sayah M, Medeiros R, Fernandes ES, Campos MM, Calixto JB. Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro. Molecular Pharmacology. 69: 1701-8. PMID 16467189 DOI: 10.1124/Mol.105.021097 |
0.391 |
|
2006 |
André E, Campi B, Trevisani M, Ferreira J, Malheiros A, Yunes RA, Calixto JB, Geppetti P. Pharmacological characterisation of the plant sesquiterpenes polygodial and drimanial as vanilloid receptor agonists. Biochemical Pharmacology. 71: 1248-54. PMID 16457780 DOI: 10.1016/J.Bcp.2005.12.030 |
0.393 |
|
2006 |
Quintão NL, Balz D, Santos AR, Campos MM, Calixto JB. Long-lasting neuropathic pain induced by brachial plexus injury in mice: Role triggered by the pro-inflammatory cytokine, tumour necrosis factor alpha. Neuropharmacology. 50: 614-20. PMID 16386767 DOI: 10.1016/J.Neuropharm.2005.11.007 |
0.358 |
|
2006 |
Meotti FC, Luiz AP, Pizzolatti MG, Kassuya CA, Calixto JB, Santos AR. Analysis of the antinociceptive effect of the flavonoid myricitrin: evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways. The Journal of Pharmacology and Experimental Therapeutics. 316: 789-96. PMID 16260583 DOI: 10.1124/Jpet.105.092825 |
0.41 |
|
2006 |
Rocha AC, Fernandes ES, Passos GF, Calixto JB, Campos MM. Corrigendum to “Assessment of TNFα contribution to the functional up-regulation of kinin B1 receptors in the mouse paw after treatment with LPS” [International Immunopharmacology 5 (11) (2005) 1593–1600] International Immunopharmacology. 6: 512. DOI: 10.1016/J.Intimp.2005.08.024 |
0.31 |
|
2005 |
Quintão NL, Medeiros R, Santos AR, Campos MM, Calixto JB. The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice. Anesthesia and Analgesia. 101: 1763-9. PMID 16301256 DOI: 10.1213/01.Ane.0000184182.03203.61 |
0.385 |
|
2005 |
Kassuya CA, Leite DF, de Melo LV, Rehder VL, Calixto JB. Anti-inflammatory properties of extracts, fractions and lignans isolated from Phyllanthus amarus. Planta Medica. 71: 721-6. PMID 16142635 DOI: 10.1055/S-2005-871258 |
0.393 |
|
2005 |
Ferreira J, Trichês KM, Medeiros R, Calixto JB. Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice. Pain. 117: 171-81. PMID 16099101 DOI: 10.1016/J.Pain.2005.06.001 |
0.403 |
|
2005 |
Rocha AC, Fernandes ES, Passos GF, Calixto JB, Campos MM. Assessment of TNFalpha contribution to the functional up-regulation of kinin B(1) receptors in the mouse paw after treatment with LPS. International Immunopharmacology. 5: 1593-600. PMID 16039549 DOI: 10.1016/J.Intimp.2005.04.007 |
0.39 |
|
2005 |
Fernandes ES, Passos GF, Campos MM, de Souza GE, Fittipaldi JF, Pesquero JL, Teixeira MM, Calixto JB. Cytokines and neutrophils as important mediators of platelet-activating factor-induced kinin B1 receptor expression. British Journal of Pharmacology. 146: 209-16. PMID 16025141 DOI: 10.1038/Sj.Bjp.0706327 |
0.346 |
|
2005 |
Campos MM, Fernandes ES, Ferreira J, Santos AR, Calixto JB. Antidepressant-like effects of Trichilia catigua (Catuaba) extract: evidence for dopaminergic-mediated mechanisms. Psychopharmacology. 182: 45-53. PMID 15991001 DOI: 10.1007/S00213-005-0052-1 |
0.342 |
|
2005 |
Rosa KA, Gadotti VM, Rosa AO, Rodrigues AL, Calixto JB, Santos AR. Evidence for the involvement of glutamatergic system in the antinociceptive effect of ascorbic acid. Neuroscience Letters. 381: 185-8. PMID 15882814 DOI: 10.1016/J.Neulet.2005.02.032 |
0.407 |
|
2005 |
Santos AR, Gadotti VM, Oliveira GL, Tibola D, Paszcuk AF, Neto A, Spindola HM, Souza MM, Rodrigues AL, Calixto JB. Mechanisms involved in the antinociception caused by agmatine in mice. Neuropharmacology. 48: 1021-34. PMID 15857629 DOI: 10.1016/J.Neuropharm.2005.01.012 |
0.386 |
|
2005 |
Schlemper V, Medeiros R, Ferreira J, Campos MM, Calixto JB. Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro. British Journal of Pharmacology. 145: 740-50. PMID 15852038 DOI: 10.1038/Sj.Bjp.0706222 |
0.356 |
|
2005 |
Ferreira J, Beirith A, Mori MA, Araújo RC, Bader M, Pesquero JB, Calixto JB. Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2405-12. PMID 15745967 DOI: 10.1523/Jneurosci.2466-04.2005 |
0.359 |
|
2005 |
Otuki MF, Vieira-Lima F, Malheiros A, Yunes RA, Calixto JB. Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene. European Journal of Pharmacology. 507: 253-9. PMID 15659316 DOI: 10.1016/J.Ejphar.2004.11.012 |
0.333 |
|
2005 |
Otuki MF, Ferreira J, Lima FV, Meyre-Silva C, Malheiros A, Muller LA, Cani GS, Santos AR, Yunes RA, Calixto JB. Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways. The Journal of Pharmacology and Experimental Therapeutics. 313: 310-8. PMID 15626726 DOI: 10.1124/Jpet.104.071779 |
0.331 |
|
2005 |
Lima FV, Malheiros A, Otuki MF, Calixto JB, Yunes RA, Cechinel Filho V, Delle Monache F. Three new triterpenes from the resinous bark of Protium kleinii and their antinociceptive activity Journal of the Brazilian Chemical Society. 16: 578-582. DOI: 10.1590/S0103-50532005000400014 |
0.317 |
|
2005 |
Yunes RA, Cechinel Filho V, Ferreira J, Calixto JB. The use of natural products as sources of new analgesic drugs Studies in Natural Products Chemistry. 30: 191-212. DOI: 10.1016/S1572-5995(05)80033-X |
0.329 |
|
2004 |
da Cunha FM, Duma D, Assreuy J, Buzzi FC, Niero R, Campos MM, Calixto JB. Caffeic acid derivatives: in vitro and in vivo anti-inflammatory properties. Free Radical Research. 38: 1241-53. PMID 15621702 DOI: 10.1080/10715760400016139 |
0.34 |
|
2004 |
Calixto JB, Medeiros R, Fernandes ES, Ferreira J, Cabrini DA, Campos MM. Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes. British Journal of Pharmacology. 143: 803-18. PMID 15520046 DOI: 10.1038/Sj.Bjp.0706012 |
0.357 |
|
2004 |
Dias Elpo Zomkowski A, Oscar Rosa A, Lin J, Santos AR, Calixto JB, Lúcia Severo Rodrigues A. Evidence for serotonin receptor subtypes involvement in agmatine antidepressant like-effect in the mouse forced swimming test. Brain Research. 1023: 253-63. PMID 15374751 DOI: 10.1016/J.Brainres.2004.07.041 |
0.308 |
|
2004 |
Campos MM, Fernandes ES, Ferreira J, Bortolanza LB, Santos AR, Calixto JB. Pharmacological and neurochemical evidence for antidepressant-like effects of the herbal product Catuama. Pharmacology, Biochemistry, and Behavior. 78: 757-64. PMID 15301932 DOI: 10.1016/J.Pbb.2004.05.024 |
0.317 |
|
2004 |
Rodrigues-Filho R, Campos MM, Ferreira J, Santos AR, Bertelli JA, Calixto JB. Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain. Brain Research. 1018: 159-70. PMID 15276874 DOI: 10.1016/J.Brainres.2004.05.058 |
0.383 |
|
2004 |
Medeiros R, Cabrini DA, Ferreira J, Fernandes ES, Mori MA, Pesquero JB, Bader M, Avellar MC, Campos MM, Calixto JB. Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein: a critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways. Circulation Research. 94: 1375-82. PMID 15087417 DOI: 10.1161/01.Res.0000128404.65887.08 |
0.35 |
|
2004 |
Siebel JS, Beirith A, Calixto JB. Evidence for the involvement of metabotropic glutamatergic, neurokinin 1 receptor pathways and protein kinase C in the antinociceptive effect of dipyrone in mice. Brain Research. 1003: 61-7. PMID 15019564 DOI: 10.1016/J.Brainres.2003.11.075 |
0.407 |
|
2004 |
Calixto JB, Campos MM, Otuki MF, Santos AR. Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Medica. 70: 93-103. PMID 14994184 DOI: 10.1055/S-2004-815483 |
0.339 |
|
2004 |
Andre E, Ferreira J, Malheiros A, Yunes RA, Calixto JB. Evidence for the involvement of vanilloid receptor in the antinociception produced by the dialdeydes unsaturated sesquiterpenes polygodial and drimanial in rats. Neuropharmacology. 46: 590-7. PMID 14975683 DOI: 10.1016/J.Neuropharm.2003.10.008 |
0.358 |
|
2004 |
Ferreira J, da Silva GL, Calixto JB. Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice. British Journal of Pharmacology. 141: 787-94. PMID 14967737 DOI: 10.1038/Sj.Bjp.0705546 |
0.446 |
|
2004 |
Passos GF, Fernandes ES, Campos MM, Araújo JG, Pesquero JL, Souza GE, Avellar MC, Teixeira MM, Calixto JB. Kinin B1 receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx. Journal of Immunology (Baltimore, Md. : 1950). 172: 1839-47. PMID 14734768 DOI: 10.4049/Jimmunol.172.3.1839 |
0.361 |
|
2003 |
Grumann Júnior A, Alves RV, Calixto JB. The role of calcium channels in substance P-induced contractile response in the rat iris. Peptides. 24: 1985-91. PMID 15127952 DOI: 10.1016/J.Peptides.2003.10.013 |
0.357 |
|
2003 |
Calixto JB, Otuki MF, Santos AR. Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB). Planta Medica. 69: 973-83. PMID 14735432 DOI: 10.1055/S-2003-45141 |
0.31 |
|
2003 |
Paulino N, Dantas AP, Bankova V, Longhi DT, Scremin A, de Castro SL, Calixto JB. Bulgarian propolis induces analgesic and anti-inflammatory effects in mice and inhibits in vitro contraction of airway smooth muscle. Journal of Pharmacological Sciences. 93: 307-13. PMID 14646248 DOI: 10.1254/Jphs.93.307 |
0.366 |
|
2003 |
Kassuya CA, Silvestre AA, Rehder VL, Calixto JB. Anti-allodynic and anti-oedematogenic properties of the extract and lignans from Phyllanthus amarus in models of persistent inflammatory and neuropathic pain. European Journal of Pharmacology. 478: 145-53. PMID 14575799 DOI: 10.1016/J.Ejphar.2003.08.079 |
0.373 |
|
2003 |
El Sayah M, Calixto JB. New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro. Peptides. 24: 1045-51. PMID 14499283 DOI: 10.1016/S0196-9781(03)00182-7 |
0.381 |
|
2003 |
Rosa AO, Lin J, Calixto JB, Santos AR, Rodrigues AL. Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice. Behavioural Brain Research. 144: 87-93. PMID 12946598 DOI: 10.1016/S0166-4328(03)00069-X |
0.366 |
|
2003 |
Rodrigues-Filho R, Santos AR, Bertelli JA, Calixto JB. Avulsion injury of the rat brachial plexus triggers hyperalgesia and allodynia in the hindpaws: a new model for the study of neuropathic pain. Brain Research. 982: 186-94. PMID 12915254 DOI: 10.1016/S0006-8993(03)03007-5 |
0.311 |
|
2003 |
Fernandes ES, Passos GF, Campos MM, Araújo JG, Pesquero JL, Avelllar MC, Teixeira MM, Calixto JB. Mechanisms underlying the modulatory action of platelet activating factor (PAF) on the upregulation of kinin B1 receptors in the rat paw. British Journal of Pharmacology. 139: 973-81. PMID 12839871 DOI: 10.1038/Sj.Bjp.0705314 |
0.381 |
|
2003 |
Santos DR, Calixto JB, Souza GE. Effect of a kinin B2 receptor antagonist on LPS- and cytokine-induced neutrophil migration in rats. British Journal of Pharmacology. 139: 271-8. PMID 12770932 DOI: 10.1038/Sj.Bjp.0705236 |
0.378 |
|
2003 |
Calixto MC, Trichês KM, Calixto JB. Analysis of the inflammatory response in the rat paw caused by the venom of Apis melifera bee. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 52: 132-9. PMID 12755378 DOI: 10.1007/S000110300026 |
0.446 |
|
2003 |
Mantovani M, Pértile R, Calixto JB, Santos AR, Rodrigues AL. Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway. Neuroscience Letters. 343: 1-4. PMID 12749983 DOI: 10.1016/S0304-3940(03)00306-9 |
0.372 |
|
2003 |
Beirith A, Santos AR, Calixto JB. The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice. Brain Research. 969: 110-6. PMID 12676371 DOI: 10.1016/S0006-8993(03)02286-8 |
0.391 |
|
2003 |
Lavich TR, Cordeiro RS, Calixto JB, e Silva PM, Martins MA. Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats. European Journal of Pharmacology. 462: 185-92. PMID 12591112 DOI: 10.1016/S0014-2999(02)02947-3 |
0.393 |
|
2003 |
André E, Malheiros A, Cechinel-Filho V, Yunes RA, Calixto JB. Role of nitric oxide and K+ channels in relaxation induced by polygodial in rabbit corpus cavernosum in vitro. Journal of Cardiovascular Pharmacology. 41: 300-6. PMID 12548092 DOI: 10.1097/00005344-200302000-00020 |
0.353 |
|
2003 |
Santos AR, Trentin AP, Ferreira J, Yunes RA, Calixto JB. Mechanisms involved in the antinociception caused by compound MV8612 isolated from Mandevilla velutina in mice. Brain Research. 961: 269-76. PMID 12531494 DOI: 10.1016/S0006-8993(02)03968-9 |
0.377 |
|
2003 |
Vianna RM, Ongali B, Regoli D, Calixto JB, Couture R. Up-regulation of kinin B1 receptor in the lung of streptozotocin-diabetic rat: autoradiographic and functional evidence. British Journal of Pharmacology. 138: 13-22. PMID 12522068 DOI: 10.1038/Sj.Bjp.0704999 |
0.348 |
|
2003 |
El Sayah M, Calixto JB. Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro. European Journal of Pharmacology. 458: 175-81. PMID 12498923 DOI: 10.1016/S0014-2999(02)02702-4 |
0.395 |
|
2002 |
Pinheiro RM, Calixto JB. Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 51: 603-10. PMID 12558194 DOI: 10.1007/Pl00012435 |
0.387 |
|
2002 |
Ferreira J, Campos MM, Araújo R, Bader M, Pesquero JB, Calixto JB. The use of kinin B1 and B2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level. Neuropharmacology. 43: 1188-97. PMID 12504926 DOI: 10.1016/S0028-3908(02)00311-8 |
0.384 |
|
2002 |
Bortalanza LB, Ferreira J, Hess SC, Delle Monache F, Yunes RA, Calixto JB. Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice. European Journal of Pharmacology. 453: 203-8. PMID 12398905 DOI: 10.1016/S0014-2999(02)02428-7 |
0.382 |
|
2002 |
Niero R, Alves RV, Filho VC, Calixto JB, Hawkes JE, Sant'Ana AE, Yunes RA. A new anti-oedematogenic nor-pregnane derivative isolated from Mandevilla illustris. Planta Medica. 68: 850-3. PMID 12357405 DOI: 10.1055/S-2002-34409 |
0.352 |
|
2002 |
Scheidt C, Santos AR, Ferreira J, Malheiros A, Cechinel-Filho V, Yunes RA, Calixto JB. Evidence for the involvement of glutamatergic receptors in the antinociception caused in mice by the sesquiterpene drimanial. Neuropharmacology. 43: 340-7. PMID 12243763 DOI: 10.1016/S0028-3908(02)00117-X |
0.395 |
|
2002 |
Paulino N, Scremin FM, Raichaski LB, Marcucci MC, Scremin A, Calixto JB. Mechanisms involved in the relaxant action of the ethanolic extract of propolis in the guinea-pig trachea in-vitro. The Journal of Pharmacy and Pharmacology. 54: 845-52. PMID 12079001 DOI: 10.1211/0022357021779023 |
0.374 |
|
2002 |
Cardozo AH, Cabrini DA, Campos MM, Rae GA, Huidobro-Toro JP, Calixto JB. Diabetes-induced changes in responsiveness of rat bladder and vas deferens to peptides in vitro: susceptibility to reversal by insulin. Canadian Journal of Physiology and Pharmacology. 80: 334-40. PMID 12025969 DOI: 10.1139/Y02-054 |
0.327 |
|
2002 |
Zomkowski AD, Hammes L, Lin J, Calixto JB, Santos AR, Rodrigues AL. Agmatine produces antidepressant-like effects in two models of depression in mice. Neuroreport. 13: 387-91. PMID 11930146 DOI: 10.1097/00001756-200203250-00005 |
0.381 |
|
2002 |
Rodrigues AL, da Silva GL, Mateussi AS, Fernandes ES, Miguel OG, Yunes RA, Calixto JB, Santos AR. Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus. Life Sciences. 70: 1347-58. PMID 11885577 DOI: 10.1016/S0024-3205(01)01498-9 |
0.37 |
|
2002 |
Campos MM, de Souza GE, Ricci ND, Pesquero JL, Teixeira MM, Calixto JB. The role of migrating leukocytes in IL-1 beta-induced up-regulation of kinin B(1) receptors in rats. British Journal of Pharmacology. 135: 1107-14. PMID 11877316 DOI: 10.1038/Sj.Bjp.0704488 |
0.383 |
|
2002 |
Beirith A, Santos AR, Calixto JB. Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw. Brain Research. 924: 219-28. PMID 11750907 DOI: 10.1016/S0006-8993(01)03240-1 |
0.352 |
|
2002 |
Rodrigues A, Rosa A, Lin J, Calixto J, Santos A. Antidepressant-like effects of zinc in mice: Possible involvement of NMDA receptors and L-arginine-nitric oxide pathway European Neuropsychopharmacology. 12: 222. DOI: 10.1016/S0924-977X(02)80255-3 |
0.319 |
|
2001 |
Calixto JB, Scheidt C, Otuki M, Santos AR. Biological activity of plant extracts: novel analgesic drugs. Expert Opinion On Emerging Drugs. 6: 261-79. PMID 15989526 DOI: 10.1517/14728214.6.2.261 |
0.318 |
|
2001 |
da Cunha FM, Fröde TS, Mendes GL, Malheiros A, Cechinel Filho V, Yunes RA, Calixto JB. Additional evidence for the anti-inflammatory and anti-allergic properties of the sesquiterpene polygodial. Life Sciences. 70: 159-69. PMID 11787941 DOI: 10.1016/S0024-3205(01)01387-X |
0.412 |
|
2001 |
Pinheiro RM, Campos MM, Calixto JB. Analysis of the mechanisms involved in the inflammatory response induced by des-Arg9-bradykinin in the rat pleural cavity. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 50: 570-6. PMID 11766997 DOI: 10.1007/Pl00000235 |
0.427 |
|
2001 |
Ferreira J, Campos MM, Pesquero JB, Araújo RC, Bader M, Calixto JB. Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B1 and B2 receptor knockout mice. Neuropharmacology. 41: 1006-12. PMID 11747905 DOI: 10.1016/S0028-3908(01)00142-3 |
0.385 |
|
2001 |
Otuki MF, Lima FV, Malheiros A, Cechinel-Filho V, Delle Monache F, Yunes RA, Calixto JB. Evaluation of the antinociceptive action caused by ether fraction and a triterpene isolated from resin of Protium kleinii. Life Sciences. 69: 2225-36. PMID 11669465 DOI: 10.1016/S0024-3205(01)01310-8 |
0.36 |
|
2001 |
Malheiros A, Filho VC, Schmitt CB, Santos ARS, Scheidt C, Calixto JB, Monache FD, Yunes RA. A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark. Phytochemistry. 57: 103-7. PMID 11336250 DOI: 10.1016/S0031-9422(00)00515-X |
0.332 |
|
2001 |
Campos MM, Cabrini DA, Cardozo AH, Rae GA, Toro JH, Calixto JB. Changes in paw oedema triggered via bradykinin B(1) and B(2) receptors in streptozotocin-diabetic rats. European Journal of Pharmacology. 416: 169-77. PMID 11282127 DOI: 10.1016/S0014-2999(01)00883-4 |
0.365 |
|
2001 |
Cunha JF, Campestrini FD, Calixto JB, Scremin A, Paulino N. The mechanism of gentisic acid-induced relaxation of the guinea pig isolated trachea: the role of potassium channels and vasoactive intestinal peptide receptors. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 34: 381-8. PMID 11262590 DOI: 10.1590/S0100-879X2001000300013 |
0.348 |
|
2001 |
Medeiros R, Cabrini DA, Calixto JB. The "in vivo" and "ex vivo" roles of cylcooxygenase-2, nuclear factor-kappaB and protein kinases pathways in the up-regulation of B1 receptor-mediated contraction of the rabbit aorta. Regulatory Peptides. 97: 121-30. PMID 11164947 DOI: 10.1016/S0167-0115(00)00186-5 |
0.399 |
|
2001 |
Fröde TS, Souza GE, Calixto JB. The modulatory role played by TNF-alpha and IL-1 beta in the inflammatory responses induced by carrageenan in the mouse model of pleurisy. Cytokine. 13: 162-8. PMID 11161459 DOI: 10.1006/Cyto.2000.0816 |
0.313 |
|
2001 |
Cabrini DA, Campos MM, Tratsk KS, Merino VF, Silva JA, Souza GE, Avellar MC, Pesquero JB, Calixto JB. Molecular and pharmacological evidence for modulation of kinin B(1) receptor expression by endogenous glucocorticoids hormones in rats. British Journal of Pharmacology. 132: 567-77. PMID 11159707 DOI: 10.1038/Sj.Bjp.0703846 |
0.384 |
|
2000 |
da Silva GD, Matteussi AS, dos Santos AR, Calixto JB, Rodrigues AL. Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice. Neuroreport. 11: 3699-702. PMID 11117475 DOI: 10.1097/00001756-200011270-00022 |
0.319 |
|
2000 |
Campos MM, Calixto JB. Neurokinin mediation of edema and inflammation. Neuropeptides. 34: 314-22. PMID 11049735 DOI: 10.1054/Npep.2000.0823 |
0.33 |
|
2000 |
Santos AR, De Campos RO, Miguel OG, Filho VC, Siani AC, Yunes RA, Calixto JB. Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae). Journal of Ethnopharmacology. 72: 229-38. PMID 10967476 DOI: 10.1016/S0378-8741(00)00256-7 |
0.356 |
|
2000 |
Fröde-Saleh TS, Calixto JB. Synergistic antiinflammatory effect of NF-kappaB inhibitors and steroidal or non steroidal antiinflammatory drugs in the pleural inflammation induced by carrageenan in mice. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 49: 330-7. PMID 10959554 DOI: 10.1007/Pl00000213 |
0.383 |
|
2000 |
Pesquero JB, Araujo RC, Heppenstall PA, Stucky CL, Silva JA, Walther T, Oliveira SM, Pesquero JL, Paiva AC, Calixto JB, Lewin GR, Bader M. Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 8140-5. PMID 10859349 DOI: 10.1073/Pnas.120035997 |
0.374 |
|
2000 |
Martini LH, Souza CR, Marques PB, Calixto JB, Yunes RA, Souza DO. Compounds extracted from Phyllantus and Jatropha elliptica inhibit the binding of [3H]glutamate and [3H]GMP-PNP in rat cerebral cortex membrane. Neurochemical Research. 25: 211-5. PMID 10786704 DOI: 10.1023/A:1007567302504 |
0.303 |
|
2000 |
El Sayah M, Filho VC, Yunes RA, Malheiros A, Calixto JB. Action of polygodial on agonist-induced contractions of the rat portal vein in vitro. Journal of Cardiovascular Pharmacology. 35: 670-5. PMID 10774800 DOI: 10.1097/00005344-200004000-00022 |
0.411 |
|
2000 |
Ferreira PK, Campos MM, Calixto JB. The role of sensorial neuropeptides in the edematogenic responses mediated by B(1) agonist des-Arg(9)-BK in rats pre-treated with LPS. Regulatory Peptides. 89: 29-35. PMID 10771310 DOI: 10.1016/S0167-0115(00)00094-X |
0.425 |
|
2000 |
Mazzuco TL, André E, Calixto JB. Contribution of nitric oxide, prostanoids and Ca(2+)-activated K+ channels to the relaxant response of bradykinin in the guinea pig bronchus in vitro. Naunyn-Schmiedeberg's Archives of Pharmacology. 361: 383-90. PMID 10763852 DOI: 10.1007/S002109900201 |
0.311 |
|
2000 |
Cechinel-Filho V, Vaz ZR, Zunino L, Calixto JB, Yunes RA. Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds. Arzneimittel-Forschung. 50: 281-5. PMID 10758782 DOI: 10.1055/S-0031-1300200 |
0.378 |
|
2000 |
Ferreira J, Floriani AE, Filho VC, Delle Monache F, Yunes RA, Calixto JB, Santos AR. Antinociceptive properties of the methanolic extract and two triterpenes isolated from Epidendrum Mosenii stems (Orchidaceae). Life Sciences. 66: 791-802. PMID 10698354 DOI: 10.1016/S0024-3205(99)00652-9 |
0.367 |
|
1999 |
Ribeiro SJ, Teixeira RM, Calixto JB, De Lima TC. Tachykinin NK(3)receptor involvement in anxiety. Neuropeptides. 33: 181-8. PMID 10657489 DOI: 10.1054/Npep.1999.0021 |
0.361 |
|
1999 |
André E, Malheiros A, Cechinel-Filho V, Yunes RA, Calixto JB. Mechanisms underlying the relaxation caused by the sesquiterpene polygodial in vessels from rabbit and guinea-pig. European Journal of Pharmacology. 386: 47-53. PMID 10611463 DOI: 10.1016/S0014-2999(99)00719-0 |
0.316 |
|
1999 |
de Campos RO, Alves RV, Ferreira J, Kyle DJ, Chakravarty S, Mavunkel BJ, Calixto JB. Oral antinociception and oedema inhibition produced by NPC 18884, a non-peptidic bradykinin B2 receptor antagonist. Naunyn-Schmiedeberg's Archives of Pharmacology. 360: 278-86. PMID 10543429 DOI: 10.1007/S002109900080 |
0.385 |
|
1999 |
Saleh TS, Calixto JB, Medeiros YS. Effects of anti-inflammatory drugs upon nitrate and myeloperoxidase levels in the mouse pleurisy induced by carrageenan. Peptides. 20: 949-56. PMID 10503773 DOI: 10.1016/S0196-9781(99)00086-8 |
0.355 |
|
1999 |
Alves RV, Campos MM, Santos AR, Calixto JB. Receptor subtypes involved in tachykinin-mediated edema formation. Peptides. 20: 921-7. PMID 10503769 DOI: 10.1016/S0196-9781(99)00082-0 |
0.36 |
|
1999 |
Ferreira J, Santos AR, Calixto JB. Antinociception produced by systemic, spinal and supraspinal administration of amiloride in mice. Life Sciences. 65: 1059-66. PMID 10499873 DOI: 10.1016/S0024-3205(99)00336-7 |
0.374 |
|
1999 |
Santos AR, De Campos RO, Miguel OG, Cechinel-Filho V, Yunes RA, Calixto JB. The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester. European Journal of Pharmacology. 379: 7-17. PMID 10499367 DOI: 10.1016/S0014-2999(99)00490-2 |
0.394 |
|
1999 |
Trentin AP, Santos AR, Guedes A, Pizzolatti MG, Yunes RA, Calixto JB. Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide. Planta Medica. 65: 517-21. PMID 10483370 DOI: 10.1055/S-1999-14007 |
0.398 |
|
1999 |
Campos MM, Souza GE, Calixto JB. In vivo B1 kinin-receptor upregulation. Evidence for involvement of protein kinases and nuclear factor kappaB pathways. British Journal of Pharmacology. 127: 1851-9. PMID 10482916 DOI: 10.1038/Sj.Bjp.0702715 |
0.336 |
|
1999 |
Ferreira J, Santos AR, Calixto JB. The role of systemic, spinal and supraspinal L-arginine-nitric oxide-cGMP pathway in thermal hyperalgesia caused by intrathecal injection of glutamate in mice. Neuropharmacology. 38: 835-42. PMID 10465687 DOI: 10.1016/S0028-3908(99)00006-4 |
0.338 |
|
1999 |
Fröde-Saleh TS, Calixto JB, Medeiros YS. Analysis of the inflammatory response induced by substance P in the mouse pleural cavity. Peptides. 20: 259-65. PMID 10422882 DOI: 10.1016/S0196-9781(98)00170-3 |
0.418 |
|
1999 |
Silva AR, Larangeira AP, Pacheco P, Calixto JB, Henriques MG, Bozza PT, Castro-Faria-Neto HC. Bradykinin down-regulates LPS-induced eosinophil accumulation in the pleural cavity of mice through type 2-kinin receptor activation: a role for prostaglandins. British Journal of Pharmacology. 127: 569-75. PMID 10385260 DOI: 10.1038/Sj.Bjp.0702567 |
0.41 |
|
1999 |
El Sayah M, Cechinel-Filho V, Pinheiro TR, Yunes RA, Calixto JB. In vitro effect of the extract and the 1,7-dihydroxy-2,3-dimethoxy xanthone from Polygala cyparissias on the contractions induced by inflammatory mediators and ovalbumin in normal and actively sensitised trachea from guinea pig. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 48: 218-23. PMID 10344473 DOI: 10.1007/S000110050449 |
0.4 |
|
1999 |
Gaertner M, Müller L, Roos JF, Cani G, Santos AR, Niero R, Calixto JB, Yunes RA, Delle Monache F, Cechinel-Filho V. Analgesic triterpenes from Sebastiania schottiana roots. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 6: 41-4. PMID 10228610 DOI: 10.1016/S0944-7113(99)80033-6 |
0.368 |
|
1999 |
Beirith A, Santos AR, Calixto JB, Hess SC, Messana I, Ferrari F, Yunes RA. Study of the antinociceptive action of the ethanolic extract and the triterpene 24-hydroxytormentic acid isolated from the stem bark of Ocotea suaveolens. Planta Medica. 65: 50-5. PMID 10083846 DOI: 10.1055/S-1999-13962 |
0.38 |
|
1999 |
Mazzuco TL, Dias MA, Calixto JB. Characterization of the mechanism involved in the relaxant response of dopexamine in the guinea pig pulmonary artery in vitro. Journal of Cardiovascular Pharmacology. 33: 86-92. PMID 9890401 DOI: 10.1097/00005344-199901000-00013 |
0.343 |
|
1998 |
Saleh TS, Vianna RM, Creczynski-Pasa TB, Chakravarty S, Mavunkel BJ, Kyle DJ, Calixto JB. Oral anti-inflammatory action of NPC 18884, a novel bradykinin B2 receptor antagonist. European Journal of Pharmacology. 363: 179-87. PMID 9881588 DOI: 10.1016/S0014-2999(98)00778-X |
0.43 |
|
1998 |
Cechinel Filho V, Schlemper V, Santos AR, Pinheiro TR, Yunes RA, Mendes GL, Calixto JB, Delle Monache F. Isolation and identification of active compounds from Drimys winteri barks. Journal of Ethnopharmacology. 62: 223-7. PMID 9849632 DOI: 10.1016/S0378-8741(98)00069-5 |
0.359 |
|
1998 |
de Campos RO, Henriques MG, Calixto JB. Systemic treatment with Mycobacterium bovis bacillus Calmette-Guérin (BCG) potentiates kinin B1 receptor agonist-induced nociception and oedema formation in the formalin test in mice. Neuropeptides. 32: 393-403. PMID 9844998 DOI: 10.1016/S0143-4179(98)90062-2 |
0.41 |
|
1998 |
de Campos RO, Paulino N, da Silva CH, Scremin A, Calixto JB. Anti-hyperalgesic effect of an ethanolic extract of propolis in mice and rats. The Journal of Pharmacy and Pharmacology. 50: 1187-93. PMID 9821669 DOI: 10.1111/J.2042-7158.1998.Tb03333.X |
0.406 |
|
1998 |
Campos MM, Souza GE, Calixto JB. Modulation of kinin B1 but not B2 receptors-mediated rat paw edema by IL-1beta and TNFalpha. Peptides. 19: 1269-76. PMID 9786178 DOI: 10.1016/S0196-9781(98)00087-4 |
0.348 |
|
1998 |
El Sayah M, Cechinel Filho V, Yunes RA, Pinheiro TR, Calixto JB. Action of polygodial, a sesquiterpene isolated from Drymis winteri, in the guinea-pig ileum and trachea 'in vitro'. European Journal of Pharmacology. 344: 215-21. PMID 9600657 DOI: 10.1016/S0014-2999(97)01570-7 |
0.371 |
|
1998 |
Luciano LG, D'Orléans-Juste P, Calixto JB, Rae GA. Endothelin-1 selectively potentiates the purinergic component of sympathetic neurotransmission in rat seminal vesicle. Journal of Cardiovascular Pharmacology. 31: S515-7. PMID 9595529 DOI: 10.1097/00005344-199800001-00148 |
0.364 |
|
1998 |
Beirith A, Santos AR, Rodrigues AL, Creczynski-Pasa TB, Calixto JB. Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action. European Journal of Pharmacology. 345: 233-45. PMID 9592021 DOI: 10.1016/S0014-2999(98)00026-0 |
0.407 |
|
1998 |
Cechinel Filho V, Corrêa R, Vaz Z, Calixto JB, Nunes RJ, Pinheiro TR, Andricopulo AD, Yunes RA. Further studies on analgesic activity of cyclic imides. Farmaco (Societã Chimica Italiana : 1989). 53: 55-7. PMID 9543727 DOI: 10.1016/S0014-827X(97)00006-2 |
0.324 |
|
1998 |
Vianna RM, Calixto JB. Characterization of the receptor and the mechanisms underlying the inflammatory response induced by des-Arg9-BK in mouse pleurisy. British Journal of Pharmacology. 123: 281-91. PMID 9489617 DOI: 10.1038/Sj.Bjp.0701590 |
0.409 |
|
1998 |
Peres MTLP, Monache FD, Pizzolatti MG, Santos ARS, Beirith A, Calixto JB, Yunes RA. Analgesic compounds ofCroton urucurana Baillon. Pharmaco-chemical criteria used in their isolation Phytotherapy Research. 12: 209-211. DOI: 10.1002/(Sici)1099-1573(199805)12:3<209::Aid-Ptr215>3.0.Co;2-P |
0.317 |
|
1997 |
Tratsk KS, Campos MM, Vaz ZR, Filho VC, Schlemper V, Yunes RA, Calixto JB. Anti-allergic effects and oedema inhibition caused by the extract of Drymis winteri. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 46: 509-14. PMID 9459082 DOI: 10.1007/S000110050234 |
0.4 |
|
1997 |
Santos AR, Calixto JB. Ruthenium red and capsazepine antinociceptive effect in formalin and capsaicin models of pain in mice. Neuroscience Letters. 235: 73-6. PMID 9389599 DOI: 10.1016/S0304-3940(97)00722-2 |
0.403 |
|
1997 |
de Campos RO, Santos AR, Vaz ZR, Pinheiro TR, Pizzolatti MG, Cechinel Filho V, Delle Monache F, Yunes RA, Calixto JB. Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae). Life Sciences. 61: 1619-30. PMID 9353171 DOI: 10.1016/S0024-3205(97)00741-8 |
0.352 |
|
1997 |
Santos AR, Calixto JB. Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice. Neuropeptides. 31: 381-9. PMID 9308027 DOI: 10.1016/S0143-4179(97)90075-5 |
0.366 |
|
1997 |
Saleh TS, Calixto JB, Medeiros YS. Pro-inflammatory effects induced by bradykinin in a murine model of pleurisy. European Journal of Pharmacology. 331: 43-52. PMID 9274929 DOI: 10.1016/S0014-2999(97)01005-4 |
0.327 |
|
1997 |
Cabrini DA, Calixto JB. Characterization of des-Arg9-bradykinin-induced contraction in guinea-pig gallbladder in vitro. European Journal of Pharmacology. 331: 31-8. PMID 9274927 DOI: 10.1016/S0014-2999(97)01010-8 |
0.413 |
|
1997 |
Wazlawik E, Da Silva MA, Peters RR, Correia JF, Farias MR, Calixto JB, Ribeiro-Do-Valle RM. Analysis of the role of nitric oxide in the relaxant effect of the crude extract and fractions from Eugenia uniflora in the rat thoracic aorta. The Journal of Pharmacy and Pharmacology. 49: 433-7. PMID 9232544 DOI: 10.1111/J.2042-7158.1997.Tb06820.X |
0.338 |
|
1997 |
el Sayah M, Cechinel Filho V, Yunes RA, Calixto JB. Action of the extract of Drymis winteri on contraction induced by inflammatory mediators, compound 48/80 and ovalbumin of the guinea-pig trachea in vitro. General Pharmacology. 28: 699-704. PMID 9184805 DOI: 10.1016/S0306-3623(96)00361-8 |
0.419 |
|
1997 |
Trentin AP, Santos AR, Miguel OG, Pizzolatti MG, Yunes RA, Calixto JB. Mechanisms involved in the antinociceptive effect in mice of the hydroalcoholic extract of Siphocampylus verticillatus. The Journal of Pharmacy and Pharmacology. 49: 567-72. PMID 9178196 DOI: 10.1111/J.2042-7158.1997.Tb06843.X |
0.382 |
|
1997 |
Campos MM, Henriques MG, Calixto JB. The role of B1 and B2 kinin receptors in oedema formation after long-term treatment with Mycobacterium bovis bacillus Calmette-Guérin (BCG). British Journal of Pharmacology. 120: 502-8. PMID 9031756 DOI: 10.1038/Sj.Bjp.0700914 |
0.387 |
|
1997 |
Vaz ZR, Mata LV, Calixto JB. Analgesic Effect of the Herbal Medicine Catuama in Thermal and Chemical Models of Nociception in Mice Phytotherapy Research. 11: 101-106. DOI: 10.1002/(Sici)1099-1573(199703)11:2<101::Aid-Ptr28>3.0.Co;2-U |
0.378 |
|
1997 |
Calixto JB, Cabrini DA. Herbal medicine Catuama induces endothelium-dependent and -independent vasorelaxant action on isolated vessels from rats, guinea-pigs and rabbits Phytotherapy Research. 11: 32-38. DOI: 10.1002/(Sici)1099-1573(199702)11:1<32::Aid-Ptr33>3.0.Co;2-C |
0.326 |
|
1996 |
Cechinel Filho V, Santos AR, De Campos RO, Miguel OG, Yunes RA, Ferrari F, Messana I, Calixto JB. Chemical and pharmacological studies of Phyllanthus caroliniensis in mice. The Journal of Pharmacy and Pharmacology. 48: 1231-6. PMID 9004183 DOI: 10.1111/J.2042-7158.1996.Tb03928.X |
0.383 |
|
1996 |
De Campos RO, Alves RV, Kyle DJ, Chakravarty S, Mavunkel BJ, Calixto JB. Antioedematogenic and antinociceptive actions of NPC 18521, a novel bradykinin B2 receptor antagonist. European Journal of Pharmacology. 316: 277-86. PMID 8982699 DOI: 10.1016/S0014-2999(96)00661-9 |
0.463 |
|
1996 |
Medeiros CL, Calixto JB. Effect of the hydroalcoholic extract of rauwolfia ligustrina on smooth and cardiac muscles in-vitro. The Journal of Pharmacy and Pharmacology. 48: 1210-4. PMID 8961175 DOI: 10.1111/J.2042-7158.1996.Tb03923.X |
0.374 |
|
1996 |
Paulino N, Cechinel-Filho V, Yunes RA, Calixto JB. The relaxant effect of extract of Phyllanthus urinaria in the guinea-pig isolated trachea. Evidence for involvement of ATP-sensitive potassium channels. The Journal of Pharmacy and Pharmacology. 48: 1158-63. PMID 8961165 DOI: 10.1111/J.2042-7158.1996.Tb03913.X |
0.379 |
|
1996 |
de Moraes VL, Rumjanek VM, Calixto JB. Jatrophone and 12-O-tetradecanoyl phorbol-13-acetate antagonism of stimulation of natural killer activity and lymphocyte proliferation. European Journal of Pharmacology. 312: 333-9. PMID 8894616 DOI: 10.1016/0014-2999(96)00488-8 |
0.342 |
|
1996 |
Teixeira RM, Santos AR, Ribeiro SJ, Calixto JB, Rae GA, De Lima TC. Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice. European Journal of Pharmacology. 311: 7-14. PMID 8884230 DOI: 10.1016/0014-2999(96)00390-1 |
0.361 |
|
1996 |
Campos MM, Souza GE, Calixto JB. Upregulation of B1 receptor mediating des-Arg9-BK-induced rat paw oedema by systemic treatment with bacterial endotoxin. British Journal of Pharmacology. 117: 793-8. PMID 8851492 DOI: 10.1111/J.1476-5381.1996.Tb15262.X |
0.423 |
|
1996 |
Paulino N, Cechinel Filho V, Pizzolatti MG, Yunes RA, Calixto JB. Mechanisms involved in the contractile responses induced by the hydroalcoholic extract of Phyllanthus urinaria on the guinea pig isolated trachea: evidence for participation of tachykinins and influx of extracellular Ca2+ sensitive to ruthenium red. General Pharmacology. 27: 795-802. PMID 8842681 DOI: 10.1016/0306-3623(95)02106-X |
0.4 |
|
1996 |
Corrêa CR, Kyle DJ, Chakraverty S, Calixto JB. Antinociceptive profile of the pseudopeptide B2 bradykinin receptor antagonist NPC 18688 in mice. British Journal of Pharmacology. 117: 552-558. PMID 8821548 DOI: 10.1111/J.1476-5381.1996.Tb15226.X |
0.477 |
|
1996 |
Saleh TS, Calixto JB, Medeiros YS. Anti-inflammatory effects of theophylline, cromolyn and salbutamol in a murine model of pleurisy. British Journal of Pharmacology. 118: 811-9. PMID 8762112 DOI: 10.1111/J.1476-5381.1996.Tb15472.X |
0.355 |
|
1996 |
Búrigo AC, Calixto JB, Medeiros YS. Pharmacological profile of rat pleurisy induced by Bothrops jararaca venom. The Journal of Pharmacy and Pharmacology. 48: 106-11. PMID 8722506 DOI: 10.1111/J.2042-7158.1996.Tb05887.X |
0.318 |
|
1996 |
Miguel OG, Calixto JB, Santos AR, Messana I, Ferrari F, Cechinel Filho V, Pizzolatti MG, Yunes RA. Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus. Planta Medica. 62: 146-9. PMID 8657748 DOI: 10.1055/S-2006-957838 |
0.363 |
|
1996 |
Filho VC, Vaz Z, Nunes RJ, Calixto JB, Yunes RA. Antinociceptive Activity of Phyllanthimide Analogues in Mice: Structure—activity Relationships Pharmacy and Pharmacology Communications. 2: 199-201. DOI: 10.1111/J.2042-7158.1996.Tb00594.X |
0.316 |
|
1996 |
Dutra FV, Calixto JB, Medeiros YS, Brum R. Jatrophone Inhibits Platelet Rich Plasma Aggregation from Man, Rat and Guinea-pig Induced by Different Agents Phytotherapy Research. 10: 271-273. DOI: 10.1002/(Sici)1099-1573(199605)10:3<271::Aid-Ptr821>3.0.Co;2-6 |
0.325 |
|
1995 |
Medeiros YS, Calixto JB. Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum. General Pharmacology. 26: 1507-11. PMID 8690237 DOI: 10.1016/0306-3623(95)00031-3 |
0.375 |
|
1995 |
Santos AR, Filho VC, Yunes RA, Calixto JB. Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus. General Pharmacology. 26: 1499-1506. PMID 8690236 DOI: 10.1016/0306-3623(95)00030-5 |
0.331 |
|
1995 |
Dias MA, Campos AH, Cechinel Filho V, Yunes RA, Calixto JB. Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea-pig urinary bladder in-vitro. The Journal of Pharmacy and Pharmacology. 47: 846-51. PMID 8583354 DOI: 10.1111/J.2042-7158.1995.Tb05752.X |
0.374 |
|
1995 |
Calixto JB. Multiple mechanisms of bradykinin-induced contraction in rat and guinea pig smooth muscles in vitro. European Journal of Pharmacology. 281: 279-88. PMID 8521911 DOI: 10.1016/0014-2999(95)00259-N |
0.359 |
|
1995 |
Santos AR, Filho VC, Niero R, Viana AM, Moreno FN, Campos MM, Yunes RA, Calixto JB. Analgesic effects of callus culture extracts from selected species of Phyllanthus in mice. The Journal of Pharmacy and Pharmacology. 46: 755-9. PMID 7837046 DOI: 10.1111/J.2042-7158.1994.Tb03897.X |
0.355 |
|
1995 |
Campos MM, Calixto JB. Involvement of B1 and B2 receptors in bradykinin-induced rat paw oedema. British Journal of Pharmacology. 114: 1005-13. PMID 7780633 DOI: 10.1111/J.1476-5381.1995.Tb13305.X |
0.429 |
|
1995 |
Silva AM, Brum RL, Calixto JB. The relaxant action of jatrophone in rat portal vein. A comparison with protein kinase C inhibitors. Life Sciences. 57: 863-71. PMID 7630315 DOI: 10.1016/0024-3205(95)02019-F |
0.349 |
|
1995 |
Maas J, Rae GA, Huidobro-Toro JP, Calixto JB. Characterization of kinin receptors modulating neurogenic contractions of the mouse isolated vas deferens. British Journal of Pharmacology. 114: 1471-7. PMID 7606350 DOI: 10.1111/J.1476-5381.1995.Tb13372.X |
0.372 |
|
1995 |
Cabrini DA, Silva AM, Calixto JB. Mechanisms of bradykinin-induced contraction of the guinea-pig gallbladder in vitro. British Journal of Pharmacology. 114: 1549-56. PMID 7599922 DOI: 10.1111/J.1476-5381.1995.Tb14938.X |
0.354 |
|
1995 |
Schlemper V, Calixto JB. Mechanisms involved in the relaxant response of bradykinin in epithelium intact strips of the guinea-pig trachea. European Journal of Pharmacology. 282: 177-84. PMID 7498273 DOI: 10.1016/0014-2999(95)00329-J |
0.364 |
|
1995 |
Santos ARS, Filho VC, Yunes RA, Calixto JB. Further Studies on the Antinociceptive Action of the Hydroalcoholic Extracts from Plants of the Genus, Phyllanthus Journal of Pharmacy and Pharmacology. 47: 66-71. DOI: 10.1111/J.2042-7158.1995.Tb05736.X |
0.333 |
|
1995 |
Filho VC, Nunes RJ, Calixto JB, Yunes RA. Inhibition of Guinea‐pig Ileum Contraction by Phyllanthimide Analogues: Structure‐activity Relationships Pharmacy and Pharmacology Communications. 1: 399-401. DOI: 10.1111/J.2042-7158.1995.Tb00450.X |
0.314 |
|
1994 |
Medeiros YS, Calixto JB. Analysis of the mechanisms underlying the biphasic responses to bradykinin in circular muscle from guinea pig ileum. European Journal of Pharmacology. 241: 157-63. PMID 8243551 DOI: 10.1016/0014-2999(93)90197-P |
0.333 |
|
1994 |
Rae GA, Calixto JB, D'Orléans-Juste P. Big-endothelin-1 contracts rat isolated uterus via a phosphoramidon-sensitive endothelin ETA receptor-mediated mechanism. European Journal of Pharmacology. 240: 113-9. PMID 8243532 DOI: 10.1016/0014-2999(93)90888-O |
0.34 |
|
1994 |
Schlemper V, Calixto JB. Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea. British Journal of Pharmacology. 111: 83-8. PMID 8012728 DOI: 10.1111/J.1476-5381.1994.Tb14027.X |
0.324 |
|
1994 |
Gorski F, Corrêa CR, Filho VC, Yunes RA, Calixto JB. Potent antinociceptive activity of a hydroalcoholic extract of Phyllanthus corcovadensis. The Journal of Pharmacy and Pharmacology. 45: 1046-9. PMID 7512649 DOI: 10.1111/J.2042-7158.1993.Tb07178.X |
0.372 |
|
1994 |
Rae GA, Calixto JB, D'Orléans-Juste P. Conversion of big endothelin-1 in rat uterus causes contraction mediated by ETA receptors. Journal of Cardiovascular Pharmacology. S192-5. PMID 7509942 DOI: 10.1097/00005344-199322008-00052 |
0.307 |
|
1993 |
Corrêa CR, Calixto JB. Evidence for participation of B1 and B2 kinin receptors in formalin-induced nociceptive response in the mouse. British Journal of Pharmacology. 110: 193-8. PMID 8220879 DOI: 10.1111/J.1476-5381.1993.Tb13791.X |
0.392 |
|
1993 |
Calixto JB, Messana I, Della Monache F, Ferrari F, Bisognin T, Yunes RA. Pharmacological analysis of the methanolic extract and sorocein A, a new Diels-Alder compound isolated from the roots of Sorocea bonplandii Bailon in the isolated rat uterus and guinea pig ileum. General Pharmacology. 24: 983-9. PMID 7901116 DOI: 10.1016/0306-3623(93)90177-Y |
0.374 |
|
1993 |
Neves MCA, Neves PCA, Zanini JC, Medeiros YS, Yunes RA, Calixto JB. Analgesic and anti-inflammatory activities of the crude hydroalcoholic extract obtained from the bark ofHymenaea martiana Phytotherapy Research. 7: 356-362. DOI: 10.1002/Ptr.2650070507 |
0.431 |
|
1992 |
Calixto JB, Yunes RA. Natural bradykinin antagonists. Memorias Do Instituto Oswaldo Cruz. 195-202. PMID 1842001 DOI: 10.1590/S0074-02761991000600045 |
0.385 |
|
1992 |
Calixto JB, Brum RL, Yunes RA. Action of pregnane compounds from Mandevilla illustris against contractions induced by kinins and other oxytocics in the rat isolated uterus. General Pharmacology. 22: 1071-5. PMID 1810805 DOI: 10.1016/0306-3623(91)90579-U |
0.34 |
|
1992 |
Guimarães CL, Calixto JB, Rae GA. Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein. Hypertension (Dallas, Tex. : 1979). 19: II79-86. PMID 1735599 DOI: 10.1161/01.Hyp.19.2_Suppl.Ii79 |
0.331 |
|
1992 |
Duarte DF, Sant'Ana AE, Calixto JB. Analysis of the vasorelaxant action of jatrophone in the isolated aorta of the rat: influence of potassium channel blockers. European Journal of Pharmacology. 215: 75-81. PMID 1516651 DOI: 10.1016/0014-2999(92)90611-7 |
0.333 |
|
1992 |
Donoso MV, Montes CG, Lewin J, Fournier A, Calixto JB, Huidobro-Toro JP. Endothelin-1 (ET)-induced mobilization of intracellular Ca2+ stores from the smooth muscle facilitates sympathetic cotransmission by potentiation of adenosine 5'-triphosphate (ATP) motor activity: studies in the rat vas deferens. Peptides. 13: 831-840. PMID 1332001 DOI: 10.1016/0196-9781(92)90193-7 |
0.301 |
|
1992 |
Calixto JB, Medeiros YS. Bradykinin-induced biphasic response in the rat isolated stomach fundus: functional evidence for a novel bradykinin receptor. Life Sciences. 50: PL47-52. PMID 1311792 DOI: 10.1016/0024-3205(92)90395-6 |
0.379 |
|
1992 |
Calixto JB, Medeiros YS. Effect of protein kinase C and calcium on bradykinin-mediated contractions of rabbit vessels. Hypertension (Dallas, Tex. : 1979). 19: II87-93. PMID 1310485 DOI: 10.1161/01.Hyp.19.2_Suppl.Ii87 |
0.315 |
|
1992 |
Calixto JB, Yunes RA, Medeiros YS. Vascular action of the crude hydroalcoholic extract fromHymenaea martiana on the isolated rat and rabbit aorta Phytotherapy Research. 6: 327-331. DOI: 10.1002/Ptr.2650060610 |
0.38 |
|
1992 |
Calixto JB, Yunes RA, Medeiros YS. Differential antagonistic effect of hydroalcoholic extract fromHymenaea martiana hayne arzeik on kinin and other agonist-induced contractions of the isolated rat uterus and Guinea-pig ileum Phytotherapy Research. 6: 322-326. DOI: 10.1002/Ptr.2650060609 |
0.394 |
|
1992 |
Zanini JC, Medeiros YS, Cruz AB, Yunes RRA, Calixto JB. Action of compounds fromMandevilla velutina on croton oil-induced ear oedema in mice. A comparative study with steroidal and nonsteroidal antiinflammatory drugs Phytotherapy Research. 6: 1-5. DOI: 10.1002/Ptr.2650060102 |
0.348 |
|
1991 |
Medeiros YS, Calixto JB. Inhibitory effect of diphenylhydantoin on myometrium from pregnant women in vitro. A comparative study with nicardipine and trifluoperazine. Pharmacological Research. 22: 597-603. PMID 2277800 DOI: 10.1016/S1043-6618(05)80051-9 |
0.321 |
|
1991 |
Calixto JB, Yunes RA. Antagonism of kinin-induced contraction of isolated rat uterus by the crude hydroalcoholic extract from Mandevilla illustris. General Pharmacology. 22: 99-101. PMID 2050294 DOI: 10.1016/0306-3623(91)90316-X |
0.369 |
|
1991 |
Calixto JB, Zanini Júnior JC, Cruz AB, Yunes RA, Medeiros YS. Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction. Prostaglandins. 41: 515-26. PMID 1907393 DOI: 10.1016/0090-6980(91)90057-M |
0.397 |
|
1991 |
Henriques MG, Fernandes PD, Weg VB, Yunes RA, Cordeiro RS, Calixto JB. Inhibition of rat paw oedema and pleurisy by the extract from Mandevilla velutina. Agents and Actions. 33: 272-8. PMID 1719783 DOI: 10.1007/Bf01986573 |
0.41 |
|
1991 |
Rae GA, Calixto JB. Effects of endothelins on nerve-mediated contractions of the mouse vas deferens. Life Sciences. 47: PL83-9. PMID 1701203 DOI: 10.1016/0024-3205(90)90191-S |
0.307 |
|
1991 |
Calixto JB, Yunes RA, Rae GA. Effect of crude extracts from Leonotis nepetaefolia (Labiatae) on rat and guinea-pig smooth muscle and rat cardiac muscle. The Journal of Pharmacy and Pharmacology. 43: 529-34. PMID 1681066 DOI: 10.1111/J.2042-7158.1991.Tb03531.X |
0.359 |
|
1991 |
Medeiros YS, Calixto JB. Influence of calcium entry blockers and calmodulin inhibitors on 5-hydroxytryptamine-, potassium- and calcium-induced contractions in human umbilical artery in-vitro. The Journal of Pharmacy and Pharmacology. 43: 411-6. PMID 1681054 DOI: 10.1111/J.2042-7158.1991.Tb03499.X |
0.306 |
|
1990 |
Strobel GH, Calixto JB, Ballejo G. Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine. Cellular and Molecular Neurobiology. 9: 469-73. PMID 2575931 DOI: 10.1007/Bf00712794 |
0.326 |
|
1990 |
Calixto JB, Miguel OG, Yunes RA, Rae GA. Action of 2-hydroxy-4,6-dimethoxyacetophenone isolated from Sebastiania schottiana. Planta Medica. 56: 31-5. PMID 2356240 DOI: 10.1055/S-2006-960878 |
0.346 |
|
1990 |
Calixto JB, Yunes RA. Blockade of kinin-induced responses of the guinea-pig isolated urinary bladder by the extract of Mandevilla velutina. General Pharmacology. 21: 285-90. PMID 2341013 DOI: 10.1016/0306-3623(90)90823-5 |
0.365 |
|
1990 |
Calixto JB, Sant'ana AE. Evidence for the mechanism of the inhibitory action of jatrophone in the isolated rat uterine muscle. General Pharmacology. 21: 117-22. PMID 1688818 DOI: 10.1016/0306-3623(90)90605-L |
0.368 |
|
1990 |
Calixto JB, Lima TCMd, Morato GS, Nicolau M, Takahashi RN, Valle RMR, Schmidt CC, Yunes RA. Chemical and pharmacological analysis of the crude aqueous/alcoholic extract from Cordyline dracaenoides Phytotherapy Research. 4: 167-171. DOI: 10.1002/Ptr.2650040502 |
0.382 |
|
1989 |
Calixto JB, Pizzolatti MG, Yunes RA. The competitive antagonistic effect of compounds from Mandevilla velutina on kinin-induced contractions of rat uterus and guinea-pig ileum in vitro. British Journal of Pharmacology. 94: 1133-42. PMID 3207977 DOI: 10.1111/J.1476-5381.1988.Tb11631.X |
0.375 |
|
1989 |
Medeiros YS, Calixto JB. Effect of induced thyroid dysfunction upon uterine responsiveness in strips from pregnant and nonpregnant rats. Pharmacology. 38: 235-42. PMID 2755963 DOI: 10.1159/000138542 |
0.314 |
|
1989 |
Trebien HA, Calixto JB. Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom. Agents and Actions. 26: 292-300. PMID 2660497 DOI: 10.1007/Bf01967293 |
0.394 |
|
1989 |
Rae GA, Calixto JB. Interactions of calcium antagonists and the calcium channel agonist Bay K 8644 on neurotransmission of the mouse isolated vas deferens. British Journal of Pharmacology. 96: 333-40. PMID 2466518 DOI: 10.1111/J.1476-5381.1989.Tb11822.X |
0.302 |
|
1988 |
Calixto JB, Nicolau M, Yunes RA. Antagonistic effect of Mandevilla velutina extract on kinin-induced contractions of guinea-pig and cat ileum longitudinal smooth muscle. General Pharmacology. 19: 595-9. PMID 3410281 DOI: 10.1016/0306-3623(88)90170-X |
0.353 |
|
1988 |
Medeiros YS, Calixto JB, Ballejo G. Inhibitory effect of GnRH on isolated rat uterine muscle contractility. Life Sciences. 42: 2055-62. PMID 3290605 DOI: 10.1016/0024-3205(88)90118-X |
0.335 |
|
1988 |
Trebien HA, Neves PCA, Yunes RA, Calixto JB. Evaluation of pharmacological activity of a crude hydroalcoholic extract fromJatropha elliptica Phytotherapy Research. 2: 115-118. DOI: 10.1002/Ptr.2650020303 |
0.383 |
|
1987 |
Ballejo G, Calixto JB, Medeiros YS. In vitro effects of calcium entry blockers, chlorpromazine and fenoterol upon human pregnant myometrium contractility. British Journal of Pharmacology. 89: 515-23. PMID 3801786 DOI: 10.1111/J.1476-5381.1986.Tb11151.X |
0.327 |
|
1987 |
Calixto JB, Nicolau M, Pizzolatti MG, Yunes RA. Kinin antagonist activity of compounds from Mandevilla velutina in the rat isolated uterus. British Journal of Pharmacology. 91: 199-204. PMID 3594076 DOI: 10.1111/J.1476-5381.1987.Tb08999.X |
0.364 |
|
1987 |
Calixto JB. Effect of diphenylhydantoin on drug and calcium induced contractions of isolated rat uterus: a comparative study with nifedipine. General Pharmacology. 18: 237-43. PMID 2436973 DOI: 10.1016/0306-3623(87)90005-X |
0.32 |
|
1987 |
Calixto JB, Sant'Ana AEG. Pharmacological analysis of the inhibitory effect of jatrophone, a diterpene isolated fromJatropha elliptica, on smooth and cardiac muscles Phytotherapy Research. 1: 122-126. DOI: 10.1002/Ptr.2650010306 |
0.332 |
|
1986 |
Calixto JB, Yunes RA. Effect of a crude extract of Mandevilla velutina on contractions induced by bradykinin and [des-Arg9]-bradykinin in isolated vessels of the rabbit. British Journal of Pharmacology. 88: 937-41. PMID 3742164 DOI: 10.1111/J.1476-5381.1986.Tb16269.X |
0.349 |
|
1986 |
Calixto JB, Nicolau M, Rae GA. Pharmacological actions of tannic acid. I. Effects on isolated smooth and cardiac muscles and on blood pressure. Planta Medica. 32-5. PMID 3703988 DOI: 10.1055/S-2007-969061 |
0.346 |
|
1986 |
Calixto JB, Antônio A. Effects of compound D600 (methoxyverapamil) on drug-induced contractions of isolated dog uterine muscle. General Pharmacology. 17: 203-9. PMID 3699446 DOI: 10.1016/0306-3623(86)90140-0 |
0.303 |
|
1986 |
Calixto J, Yunes R, Miguel O, Rae G. Effects ofSebastiana schottianaExtracts on Isolated Smooth Muscle Contraction Planta Medica. 52: 444-445. DOI: 10.1055/S-2007-969249 |
0.304 |
|
1985 |
Calixto JB, Nicolau M, Yunes RA. The selective antagonism of bradykinin action on rat isolated uterus by crude Mandevilla velutina extract. British Journal of Pharmacology. 85: 729-31. PMID 4041675 DOI: 10.1111/J.1476-5381.1985.Tb11069.X |
0.361 |
|
1985 |
Calixto JB, Loch S. Ketamine-inhibition of calcium-induced contractions in depolarized rat uterus: a comparison with other calcium antagonists. British Journal of Pharmacology. 85: 189-95. PMID 4027464 DOI: 10.1111/J.1476-5381.1985.Tb08846.X |
0.334 |
|
1985 |
Calixto JB, Antonio A. The effect of barium on the contractile mechanism of isolated dog uteri: Influence of the hormonal state Animal Reproduction Science. 8: 375-388. DOI: 10.1016/0378-4320(85)90052-1 |
0.312 |
|
1984 |
Calixto JB, Simas CM. Mechanism of action of isoprenaline, isoxuprine, terbutaline and orciprenaline on gravid human isolated myometrium. Influence of the neuronal uptake process. Biology of Reproduction. 30: 1117-23. PMID 6145456 DOI: 10.1095/Biolreprod30.5.1117 |
0.34 |
|
1982 |
Calixto JB, Rae GA. Influence of castration of the neonatal rat on the pharmacological reactivity of the isolated vas deferens. Biology of Reproduction. 25: 481-6. PMID 7030416 DOI: 10.1095/Biolreprod25.3.481 |
0.304 |
|
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