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Lit-Hsin Loo, Ph.D. - Publications

Affiliations: 
2004 Drexel University, Philadelphia, PA, United States 
Area:
Biostatistics Biology, Biomedical Engineering
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Miller JA, Loo LH. Optimum concentration-response curve metrics for supervised selection of discriminative cellular phenotypic endpoints for chemical hazard assessment. Archives of Toxicology. PMID 32601827 DOI: 10.1007/S00204-020-02813-3  0.367
2020 Hussain F, Basu S, Heng JJH, Loo LH, Zink D. Predicting direct hepatocyte toxicity in humans by combining high-throughput imaging of HepaRG cells and machine learning-based phenotypic profiling. Archives of Toxicology. PMID 32533217 DOI: 10.1007/S00204-020-02778-3  0.381
2020 Van Der Ven L, Rorije E, Sprong C, Zink D, Derr R, Hendriks G, Loo LH, Luijten M. A case study with triazole fungicides to explore practical application of next generation hazard assessment methods for human health. Chemical Research in Toxicology. PMID 32041405 DOI: 10.1021/Acs.Chemrestox.9B00484  0.312
2019 Friedman KP, Gagne M, Loo LH, Karamertzanis P, Netzeva T, Sobanski T, Franzosa J, Richard A, Lougee R, Gissi A, Lee JJ, Angrish M, Dorne JL, Foster S, Raffaele K, et al. Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31532525 DOI: 10.1093/Toxsci/Kfz201  0.326
2018 Lee JJ, Miller JA, Basu S, Kee TV, Loo LH. Building predictive in vitro pulmonary toxicity assays using high-throughput imaging and artificial intelligence. Archives of Toxicology. PMID 29705884 DOI: 10.1007/S00204-018-2213-0  0.366
2017 Loo LH, Zink D. High-throughput prediction of nephrotoxicity in humans. Alternatives to Laboratory Animals : Atla. 45: 241-252. PMID 29112452 DOI: 10.1177/026119291704500506  0.334
2015 Su R, Xiong S, Zink D, Loo LH. High-throughput imaging-based nephrotoxicity prediction for xenobiotics with diverse chemical structures. Archives of Toxicology. PMID 26612367 DOI: 10.1007/S00204-015-1638-Y  0.379
2015 Kandasamy K, Chuah JK, Su R, Huang P, Eng KG, Xiong S, Li Y, Chia CS, Loo LH, Zink D. Prediction of drug-induced nephrotoxicity and injury mechanisms with human induced pluripotent stem cell-derived cells and machine learning methods. Scientific Reports. 5: 12337. PMID 26212763 DOI: 10.1038/Srep12337  0.323
2014 Su R, Li Y, Zink D, Loo LH. Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and -8 expression levels. Bmc Bioinformatics. 15: S16. PMID 25521947 DOI: 10.1186/1471-2105-15-S16-S16  0.307
2013 Laksameethanasan D, Tan R, Toh G, Loo LH. cellXpress: a fast and user-friendly software platform for profiling cellular phenotypes. Bmc Bioinformatics. 14: S4. PMID 24564609 DOI: 10.1186/1471-2105-14-S16-S4  0.305
2009 Loo LH, Lin HJ, Steininger RJ, Wang Y, Wu LF, Altschuler SJ. An approach for extensibly profiling the molecular states of cellular subpopulations. Nature Methods. 6: 759-65. PMID 19767759 DOI: 10.1038/Nmeth.1375  0.345
2007 Loo LH, Roberts S, Hrebien L, Kam M. New criteria for selecting differentially expressed genes. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 26: 17-26. PMID 17441605 DOI: 10.1109/Memb.2007.335589  0.517
2007 Loo LH, Wu LF, Altschuler SJ. Image-based multivariate profiling of drug responses from single cells. Nature Methods. 4: 445-53. PMID 17401369 DOI: 10.1038/Nmeth1032  0.375
2005 Loo LH, Roberts S, Hrebien L, Kam M. New filter-based feature selection criteria for identifying differentially expressed genes Proceedings - Icmla 2005: Fourth International Conference On Machine Learning and Applications. 2005: 135-144. DOI: 10.1109/ICMLA.2005.48  0.499
2003 Loo LH, Quinn J, Cordingley H, Roberts S, Hrebien L, Kam M. Classification of SELDI-ToF mass spectra of ovarian cancer serum samples using a proteomic pattern recognizer Bioengineering, Proceedings of the Northeast Conference. 130-131. DOI: 10.1109/NEBC.2003.1216026  0.492
2003 Loo LH, Quinn J, Cordingley H, Roberts S, Hrebien L, Kam M. Common Characteristics and Noise Filtering and its Application in a Proteomic Pattern Recognition System for Cancer Detection Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 3: 2897-2900.  0.493
2003 Quinn J, Loo LH, Achuthanandam R, Bugelski P, Capocasale R, Kam M, Hrebien L. Determining Regions of Interest in Flow Cytometric Data Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 1307-1310.  0.456
2002 Quinn J, Loo LH, Armitage J, Cordingley H, Roberts S, Bugelski PJ, Kam M, Hrebien L. Classification of pharmaceutical toxicity by feature analysis Bioengineering, Proceedings of the Northeast Conference. 211-212. DOI: 10.1109/NEBC.2002.999540  0.493
2002 Loo LH, Quinn J, Armitage J, Cordingley H, Roberts S, Bugelski PJ, Hrebien L, Kam M. Classification of polypeptide spectra from rat liver samples Bioengineering, Proceedings of the Northeast Conference. 139-140. DOI: 10.1109/NEBC.2002.999504  0.451
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