Brendan D. Price - Publications

Affiliations: 
Biological Sciences in Public Health Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Serafim RB, Cardoso C, Storti CB, da Silva P, Qi H, Parasuram R, Navegante G, Peron JPS, Silva WA, Espreafico EM, Paçó-Larson ML, Price BD, Valente V. HJURP is recruited to double-strand break sites and facilitates DNA repair by promoting chromatin reorganization. Oncogene. PMID 38279062 DOI: 10.1038/s41388-024-02937-1  0.459
2022 Qi H, Grace Wright RH, Beato M, Price BD. The ADP-ribose hydrolase NUDT5 is important for DNA repair. Cell Reports. 41: 111866. PMID 36543120 DOI: 10.1016/j.celrep.2022.111866  0.413
2020 House NCM, Parasuram R, Layer JV, Price BD. Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage. Plos One. 15: e0237759. PMID 33332350 DOI: 10.1371/journal.pone.0237759  0.374
2020 Layer JV, Debaize L, Van Scoyk A, House NC, Brown AJ, Liu Y, Stevenson KE, Hemann M, Roberts SA, Price BD, Weinstock DM, Day TA. Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. PMID 33077594 DOI: 10.1073/pnas.2014176117  0.382
2019 Serafim RB, Cardoso C, Di Cristofaro LFM, Pienna Soares C, Araújo Silva W, Espreafico EM, Paçó-Larson ML, Price BD, Valente V. HJURP knockdown disrupts clonogenic capacity and increases radiation-induced cell death of glioblastoma cells. Cancer Gene Therapy. PMID 31138900 DOI: 10.1038/S41417-019-0103-0  0.356
2019 Qi H, Price BD, Day TA. Multiple Roles for Mono- and Poly(ADP-Ribose) in Regulating Stress Responses. Trends in Genetics : Tig. 35: 159-172. PMID 30595401 DOI: 10.1016/J.Tig.2018.12.002  0.313
2019 Pal S, Bian J, Price B, Chowdhury D, Haas-Kogan D. PDTM-41. INHIBITION OF DNA DOUBLE STRAND BREAK REPAIR PATHWAYS AS A PROMISING THERAPEUTIC TARGET IN DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs) Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.816  0.419
2018 Zhou J, Li J, Serafim RB, Ketchum S, Ferreira CG, Liu JC, Coe KA, Price BD, Yusufzai T. Human CHD1 is required for early DNA-damage signaling and is uniquely regulated by its N terminus. Nucleic Acids Research. PMID 29529298 DOI: 10.1093/Nar/Gky128  0.485
2017 Gursoy-Yuzugullu O, Carman C, Price BD. Spatially restricted loading of BRD2 at DNA double-strand breaks protects H4 acetylation domains and promotes DNA repair. Scientific Reports. 7: 12921. PMID 29018219 DOI: 10.1038/S41598-017-13036-5  0.466
2017 Ströbel T, Madlener S, Tuna S, Vose S, Lagerweij T, Wurdinger T, Vierlinger K, Wöhrer A, Price BD, Demple B, Saydam O, Saydam N. Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma. Scientific Reports. 7: 9674. PMID 28852018 DOI: 10.1038/S41598-017-10013-W  0.517
2017 Dhar S, Gursoy-Yuzugullu O, Parasuram R, Price BD. The tale of a tail: histone H4 acetylation and the repair of DNA breaks. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28847821 DOI: 10.1098/Rstb.2016.0284  0.456
2017 Day TA, Layer JV, Cleary JP, Guha S, Stevenson KE, Tivey T, Kim S, Schinzel AC, Izzo F, Doench J, Root DE, Hahn WC, Price BD, Weinstock DM. Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA. Nature Communications. 8: 15918. PMID 28607496 DOI: 10.1038/Ncomms15918  0.376
2017 Price BD. KDM5A demethylase: Erasing histone modifications to promote repair of DNA breaks. Journal of Cell Biology. 216: 1871-1873. PMID 28572116 DOI: 10.1083/Jcb.201705005  0.487
2017 Day TA, Layer JV, Cleary JP, Guha S, Stevenson KE, Tivey T, Kim S, Schinzel AC, Izzo F, Doench J, Root DE, Hahn WC, Price BD, Weinstock DM. PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA. Nature Communications. 8: 15110. PMID 28447610 DOI: 10.1038/Ncomms15110  0.487
2017 Gursoy-Yuzugullu O, Carman C, Serafim RB, Myronakis M, Valente V, Price BD. Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity. Oncotarget. 8: 24518-24532. PMID 28445939 DOI: 10.18632/Oncotarget.15543  0.456
2017 Vallaster C, Gharadaghi F, Cocozaki A, Jacques K, Price B, Guichard S. Abstract B14: A novel role for BRD9 in regulating cellular growth and DNA damage response pathways Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-B14  0.505
2015 Gursoy-Yuzugullu O, House N, Price BD. Patching broken DNA: Nucleosome dynamics and the repair of DNA breaks. Journal of Molecular Biology. PMID 26625977 DOI: 10.1016/J.Jmb.2015.11.021  0.507
2015 Gursoy-Yuzugullu O, Ayrapetov MK, Price BD. Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair. Proceedings of the National Academy of Sciences of the United States of America. 112: 7507-12. PMID 26034280 DOI: 10.1073/Pnas.1504868112  0.436
2015 Stroebel T, Madlener S, Tuna S, Vose S, Morse D, Tannous BA, Lagerweij T, Wurdinger T, Marosi C, Slavc I, Vierlinger K, Saydam O, Price BD, Demple B, Saydam N. Abstract B26: Ape1/Ref-1 directs DNA repair pathway choice, linked to Chk2 signaling, critical for glioblastoma response to chemotherapy Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B26  0.5
2015 Gursoy-Yuzugullu O, Ayrapetov MK, Price BD. Correction for "Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair" Proceedings of the National Academy of Sciences of the United States of America. 112: E3750. DOI: 10.1073/pnas.1511770112  0.397
2014 Du F, Zhang M, Li X, Yang C, Meng H, Wang D, Chang S, Xu Y, Price B, Sun Y. Dimer monomer transition and dimer re-formation play important role for ATM cellular function during DNA repair. Biochemical and Biophysical Research Communications. 452: 1034-9. PMID 25240135 DOI: 10.1016/J.Bbrc.2014.09.038  0.508
2014 Ayrapetov MK, Gursoy-Yuzugullu O, Xu C, Xu Y, Price BD. DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin. Proceedings of the National Academy of Sciences of the United States of America. 111: 9169-74. PMID 24927542 DOI: 10.1073/Pnas.1403565111  0.477
2013 Madlener S, Ströbel T, Vose S, Saydam O, Price BD, Demple B, Saydam N. Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance. Proceedings of the National Academy of Sciences of the United States of America. 110: 17844-9. PMID 24127576 DOI: 10.1073/Pnas.1304784110  0.504
2013 Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D'Andrea AD. FANCD2 activates transcription of TAp63 and suppresses tumorigenesis. Molecular Cell. 50: 908-18. PMID 23806336 DOI: 10.1016/J.Molcel.2013.05.017  0.38
2013 Price BD, D'Andrea AD. Chromatin remodeling at DNA double-strand breaks. Cell. 152: 1344-54. PMID 23498941 DOI: 10.1016/J.Cell.2013.02.011  0.508
2012 Berbeco RI, Korideck H, Ngwa W, Kumar R, Patel J, Sridhar S, Johnson S, Price BD, Kimmelman A, Makrigiorgos GM. DNA damage enhancement from gold nanoparticles for clinical MV photon beams. Radiation Research. 178: 604-8. PMID 23148509 DOI: 10.1667/Rr3001.1  0.371
2012 Xu Y, Ayrapetov MK, Xu C, Gursoy-Yuzugullu O, Hu Y, Price BD. Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair. Molecular Cell. 48: 723-33. PMID 23122415 DOI: 10.1016/J.Molcel.2012.09.026  0.441
2012 Xu C, Xu Y, Gursoy-Yuzugullu O, Price BD. The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1. Febs Letters. 586: 3920-5. PMID 23031826 DOI: 10.1016/J.Febslet.2012.09.030  0.485
2012 Xu Y, Xu C, Price BD. Mechanistic links between ATM and histone methylation codes during DNA repair. Progress in Molecular Biology and Translational Science. 110: 263-88. PMID 22749149 DOI: 10.1016/B978-0-12-387665-2.00010-9  0.518
2011 Ayrapetov MK, Xu C, Sun Y, Zhu K, Parmar K, D'Andrea AD, Price BD. Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. Plos One. 6: e26064. PMID 22016813 DOI: 10.1371/Journal.Pone.0026064  0.461
2011 Xu Y, Price BD. Chromatin dynamics and the repair of DNA double strand breaks. Cell Cycle (Georgetown, Tex.). 10: 261-7. PMID 21212734 DOI: 10.4161/Cc.10.2.14543  0.525
2011 Xu Y, Parmar K, Du F, Price BD, Sun Y. The radioprotective agent WR1065 protects cells from radiation damage by regulating the activity of the tip60 acetyltransferase International Journal of Biochemistry and Molecular Biology. 2: 295-302.  0.35
2010 Xu Y, Sun Y, Jiang X, Ayrapetov MK, Moskwa P, Yang S, Weinstock DM, Price BD. The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair. The Journal of Cell Biology. 191: 31-43. PMID 20876283 DOI: 10.1083/Jcb.201001160  0.518
2010 Weng D, Cunin MC, Song B, Price BD, Eller MS, Gilchrest BA, Calderwood SK, Gong J. Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment. Breast Cancer Research : Bcr. 12: R71. PMID 20846433 DOI: 10.1186/Bcr2639  0.305
2010 Lin CI, Whang EE, Donner DB, Du J, Lorch J, He F, Jiang X, Price BD, Moore FD, Ruan DT. Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer. Molecular Cancer Research : McR. 8: 1217-26. PMID 20736296 DOI: 10.1158/1541-7786.Mcr-10-0162  0.357
2010 Jiang X, Xu Y, Price BD. Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway. Febs Letters. 584: 2926-30. PMID 20488183 DOI: 10.1016/J.Febslet.2010.05.017  0.541
2010 Sun Y, Jiang X, Price BD. Tip60: connecting chromatin to DNA damage signaling. Cell Cycle (Georgetown, Tex.). 9: 930-6. PMID 20160506 DOI: 10.4161/Cc.9.5.10931  0.562
2010 Dutta C, Song F, Price B, Letai A, Weinstock DM. Abstract 1974: Nuclear BCL2 inhibits PARP1 enzymatic activity, DNA repair, and necrotic cell death Cancer Research. 70: 1974-1974. DOI: 10.1158/1538-7445.Am10-1974  0.463
2009 Lin CI, Whang EE, Donner DB, Jiang X, Price BD, Carothers AM, Delaine T, Leffler H, Nilsson UJ, Nose V, Moore FD, Ruan DT. Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer. Molecular Cancer Research : McR. 7: 1655-62. PMID 19825987 DOI: 10.1158/1541-7786.Mcr-09-0274  0.316
2009 Sun Y, Jiang X, Xu Y, Ayrapetov MK, Moreau LA, Whetstine JR, Price BD. Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nature Cell Biology. 11: 1376-82. PMID 19783983 DOI: 10.1038/Ncb1982  0.524
2009 Sun Y, Price B. Abstract B40: Histone H3 methylation couples DNA damage detection to activation of the Tip60 tumor suppressor Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B40  0.411
2007 Sun Y, Xu Y, Roy K, Price BD. DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity. Molecular and Cellular Biology. 27: 8502-9. PMID 17923702 DOI: 10.1128/Mcb.01382-07  0.472
2007 Fernandes ND, Sun Y, Price BD. Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells. The Journal of Biological Chemistry. 282: 16577-84. PMID 17426037 DOI: 10.1074/Jbc.M609628200  0.451
2006 Sun Y, Jiang X, Chen S, Price BD. Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. Febs Letters. 580: 4353-6. PMID 16844118 DOI: 10.1016/J.Febslet.2006.06.092  0.527
2006 Roy K, Wang L, Makrigiorgos GM, Price BD. Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity. Biochemical and Biophysical Research Communications. 344: 821-6. PMID 16631604 DOI: 10.1016/J.Bbrc.2006.03.222  0.364
2006 Jiang X, Sun Y, Chen S, Roy K, Price BD. The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM. The Journal of Biological Chemistry. 281: 15741-6. PMID 16603769 DOI: 10.1074/Jbc.M513172200  0.516
2005 Sun Y, Jiang X, Chen S, Fernandes N, Price BD. A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proceedings of the National Academy of Sciences of the United States of America. 102: 13182-7. PMID 16141325 DOI: 10.1073/Pnas.0504211102  0.548
2005 Fernandes N, Sun Y, Chen S, Paul P, Shaw RJ, Cantley LC, Price BD. DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. The Journal of Biological Chemistry. 280: 15158-64. PMID 15713674 DOI: 10.1074/Jbc.M412065200  0.495
2004 Wang G, Brennan C, Rook M, Wolfe JL, Leo C, Chin L, Pan H, Liu WH, Price B, Makrigiorgos GM. Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples. Nucleic Acids Research. 32: e76. PMID 15155823 DOI: 10.1093/Nar/Gnh070  0.41
2004 Chen S, Wang G, Makrigiorgos GM, Price BD. Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells. Biochemical and Biophysical Research Communications. 317: 1037-44. PMID 15094373 DOI: 10.1016/J.Bbrc.2004.03.149  0.433
2003 Chen S, Paul P, Price BD. ATM's leucine-rich domain and adjacent sequences are essential for ATM to regulate the DNA damage response. Oncogene. 22: 6332-9. PMID 14508513 DOI: 10.1038/Sj.Onc.1206760  0.491
2002 Kaur M, Zhang Y, Liu WH, Tetradis S, Price BD, Makrigiorgos GM. Ligation of a primer at a mutation: a method to detect low level mutations in DNA. Mutagenesis. 17: 365-74. PMID 12202623 DOI: 10.1093/Mutage/17.5.365  0.335
2002 Makrigiorgos GM, Chakrabarti S, Zhang Y, Kaur M, Price BD. A PCR-based amplification method retaining the quantitative difference between two complex genomes. Nature Biotechnology. 20: 936-9. PMID 12161758 DOI: 10.1038/Nbt724  0.39
2002 Zhang Y, Kaur M, Price BD, Tetradis S, Makrigiorgos GM. An amplification and ligation-based method to scan for unknown mutations in DNA. Human Mutation. 20: 139-47. PMID 12124995 DOI: 10.1002/Humu.10106  0.409
2001 Turenne GA, Paul P, Laflair L, Price BD. Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53. Oncogene. 20: 5100-10. PMID 11526498 DOI: 10.1038/Sj.Onc.1204665  0.467
2001 Turenne GA, Price BD. Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity. Bmc Cell Biology. 2: 12. PMID 11483158 DOI: 10.1186/1471-2121-2-12  0.346
2001 Zhang Y, Price BD, Tetradis S, Chakrabarti S, Maulik G, Makrigiorgos GM. Reproducible and inexpensive probe preparation for oligonucleotide arrays. Nucleic Acids Research. 29: E66-6. PMID 11433042 DOI: 10.1093/Nar/29.13.E66  0.334
1999 Palayoor ST, Youmell MY, Calderwood SK, Coleman CN, Price BD. Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene. 18: 7389-94. PMID 10602496 DOI: 10.1038/Sj.Onc.1203160  0.361
1999 Blasina A, Price BD, Turenne GA, McGowan CH. Caffeine inhibits the checkpoint kinase ATM. Current Biology : Cb. 9: 1135-8. PMID 10531013 DOI: 10.1016/S0960-9822(99)80486-2  0.504
1999 Maulik G, Botchway S, Chakrabarti S, Tetradis S, Price B, Makrigiorgos GM. Novel non-isotopic detection of MutY enzyme-recognized mismatches in DNA via ultrasensitive detection of aldehydes. Nucleic Acids Research. 27: 1316-22. PMID 9973620 DOI: 10.1093/Nar/27.5.1316  0.397
1998 Maulik N, Sato M, Price BD, Das DK. An essential role of NFkappaB in tyrosine kinase signaling of p38 MAP kinase regulation of myocardial adaptation to ischemia. Febs Letters. 429: 365-9. PMID 9662450 DOI: 10.1016/S0014-5793(98)00632-2  0.3
1998 Basu S, Rosenzweig KR, Youmell M, Price BD. The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage. Biochemical and Biophysical Research Communications. 247: 79-83. PMID 9636658 DOI: 10.1006/Bbrc.1998.8741  0.429
1998 Youmell M, Park SJ, Basu S, Price BD. Regulation of the p53 protein by protein kinase C alpha and protein kinase C zeta. Biochemical and Biophysical Research Communications. 245: 514-8. PMID 9571186 DOI: 10.1006/Bbrc.1998.8471  0.363
1997 Rosenzweig KE, Youmell MB, Palayoor ST, Price BD. Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 3: 1149-56. PMID 9815794  0.414
1997 Rosenzweig KE, Youmell MB, Price BD. 21 DNA-dependent protein kinase participates in the radiation activation of NF-kB International Journal of Radiation Oncology Biology Physics. 39: 145. DOI: 10.1016/S0360-3016(97)80578-0  0.455
1996 Chu B, Soncin F, Price BD, Stevenson MA, Calderwood SK. Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1. The Journal of Biological Chemistry. 271: 30847-57. PMID 8940068 DOI: 10.1074/Jbc.271.48.30847  0.347
1996 Price BD, Youmell MB. The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage. Cancer Research. 56: 246-50. PMID 8542574  0.365
1994 Price BD, Park SJ. DNA damage increases the levels of MDM2 messenger RNA in wtp53 human cells. Cancer Research. 54: 896-9. PMID 8313378  0.397
1993 Tishler RB, Calderwood SK, Coleman CN, Price BD. Increases in Sequence Specific DNA Binding by p53 following Treatment with Chemotherapeutic and DNA Damaging Agents1 Cancer Research. 53: 2212-2216. PMID 8485705  0.394
1993 Price BD, Calderwood SK. Increased sequence-specific p53-DNA binding activity after DNA damage is attenuated by phorbol esters Oncogene. 8: 3055-3062. PMID 8414506  0.422
1993 Calderwood SK, Stevenson MA, Price BD. Activation of phospholipase C by heat shock requires GTP analogs and is resistant to pertussis toxin Journal of Cellular Physiology. 156: 153-159. PMID 8314854 DOI: 10.1002/Jcp.1041560121  0.302
1993 Tishler RB, Calderwood SK, Coleman CN, Price BD. DNA damaging agents increase sequence specific dna binding by p53(astro fellowship) International Journal of Radiation Oncology Biology Physics. 27: 211-212. DOI: 10.1016/0360-3016(93)90765-N  0.439
1992 Price BD, Mannheim-Rodman LA, Calderwood SK. Brefeldin A, thapsigargin, and AlF4- stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis Journal of Cellular Physiology. 152: 545-552. PMID 1506413 DOI: 10.1002/Jcp.1041520314  0.321
1991 Price BD, Calderwood SK. Ca2+ is essential for multistep activation of the heat shock factor in permeabilized cells Molecular and Cellular Biology. 11: 3365-3368. PMID 2038338 DOI: 10.1128/Mcb.11.6.3365  0.3
1989 Price BD, Morris JD, Marshall CJ, Hall A. Scrape-loaded p21ras down-regulates agonist-stimulated inositol phosphate production by a mechanism involving protein kinase C. The Biochemical Journal. 260: 157-61. PMID 2549949 DOI: 10.1042/Bj2600157  0.313
Show low-probability matches.