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Zhenming Xu, Ph.D. - Publications

Affiliations: 
2002 University of Southern California, Los Angeles, CA, United States 
Area:
Microbiology Biology, Molecular Biology
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gan H, Shen T, Chupp DP, Taylor JR, Sanchez HN, Li X, Xu Z, Zan H, Casali P. B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response. Science Advances. 6: eaay2793. PMID 32270032 DOI: 10.1126/Sciadv.Aay2793  0.364
2020 Yan H, Fernandez M, Wang J, Wu S, Wang R, Lou Z, Moroney JB, Rivera CE, Taylor JR, Gan H, Zan H, Kolvaskyy D, Liu D, Casali P, Xu Z. B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching. Journal of Immunology (Baltimore, Md. : 1950). PMID 31932498 DOI: 10.4049/Jimmunol.1901170  0.338
2017 Lam T, Thomas LM, White CA, Li G, Pone EJ, Xu Z, Casali P. Correction: Scaffold Functions of 14-3-3 Adaptors in B Cell Immunoglobulin Class Switch DNA Recombination. Plos One. 12: e0174195. PMID 28296964 DOI: 10.1371/Journal.Pone.0174195  0.314
2016 Lam T, Kulp DV, Wang R, Lou Z, Taylor J, Rivera CE, Yan H, Zhang Q, Wang Z, Zan H, Ivanov DN, Zhong G, Casali P, Xu Z. Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus. Journal of Immunology (Baltimore, Md. : 1950). PMID 27742832 DOI: 10.4049/Jimmunol.1601427  0.339
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Xu ZX, ... ... Xu Z, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.438
2015 Lou Z, Casali P, Xu Z. Regulation of B Cell Differentiation by Intracellular Membrane-Associated Proteins and microRNAs: Role in the Antibody Response. Frontiers in Immunology. 6: 537. PMID 26579118 DOI: 10.3389/Fimmu.2015.00537  0.36
2015 Pone EJ, Lam T, Lou Z, Wang R, Chen Y, Liu D, Edinger AL, Xu Z, Casali P. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. Journal of Immunology (Baltimore, Md. : 1950). 194: 3065-78. PMID 25740947 DOI: 10.4049/Jimmunol.1401896  0.381
2015 Pone EJ, Lou Z, Lam T, Greenberg ML, Wang R, Xu Z, Casali P. B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses. Autoimmunity. 48: 1-12. PMID 25536171 DOI: 10.3109/08916934.2014.993027  0.333
2013 Lam T, Thomas LM, White CA, Li G, Pone EJ, Xu Z, Casali P. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. Plos One. 8: e80414. PMID 24282540 DOI: 10.1371/Journal.Pone.0080414  0.385
2013 Li G, White CA, Lam T, Pone EJ, Tran DC, Hayama KL, Zan H, Xu Z, Casali P. Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination. Cell Reports. 5: 702-14. PMID 24209747 DOI: 10.1016/J.Celrep.2013.09.031  0.304
2013 Mai T, Pone EJ, Li G, Lam TS, Moehlman J, Xu Z, Casali P. Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A. Journal of Immunology (Baltimore, Md. : 1950). 191: 1895-906. PMID 23851690 DOI: 10.4049/Jimmunol.1300922  0.369
2013 Li G, Zan H, Xu Z, Casali P. Epigenetics of the antibody response. Trends in Immunology. 34: 460-70. PMID 23643790 DOI: 10.1016/J.It.2013.03.006  0.354
2012 Zan H, White CA, Thomas LM, Mai T, Li G, Xu Z, Zhang J, Casali P. Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination. Cell Reports. 2: 1220-32. PMID 23140944 DOI: 10.1016/J.Celrep.2012.09.029  0.357
2012 Xu Z, Zan H, Pone EJ, Mai T, Casali P. Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nature Reviews. Immunology. 12: 517-31. PMID 22728528 DOI: 10.1038/Nri3216  0.34
2012 Pone EJ, Xu Z, White CA, Zan H, Casali P. B cell TLRs and induction of immunoglobulin class-switch DNA recombination. Frontiers in Bioscience (Landmark Edition). 17: 2594-615. PMID 22652800 DOI: 10.2741/4073  0.356
2012 Li G, Pone EJ, Tran DC, Patel PJ, Dao L, Xu Z, Casali P. Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination. The Journal of Biological Chemistry. 287: 21520-9. PMID 22556412 DOI: 10.1074/Jbc.M112.366732  0.35
2012 Pone EJ, Zhang J, Mai T, White CA, Li G, Sakakura JK, Patel PJ, Al-Qahtani A, Zan H, Xu Z, Casali P. BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway. Nature Communications. 3: 767. PMID 22473011 DOI: 10.1038/Ncomms1769  0.323
2010 Mai T, Zan H, Zhang J, Hawkins JS, Xu Z, Casali P. Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation. The Journal of Biological Chemistry. 285: 37797-810. PMID 20855884 DOI: 10.1074/Jbc.M110.169086  0.358
2010 Xu Z, Fulop Z, Wu G, Pone EJ, Zhang J, Mai T, Thomas LM, Al-Qahtani A, White CA, Park SR, Steinacker P, Li Z, Yates J, Herron B, Otto M, et al. 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nature Structural & Molecular Biology. 17: 1124-35. PMID 20729863 DOI: 10.1038/Nsmb.1884  0.363
2010 Pone EJ, Zan H, Zhang J, Al-Qahtani A, Xu Z, Casali P. Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses. Critical Reviews in Immunology. 30: 1-29. PMID 20370617 DOI: 10.1615/Critrevimmunol.V30.I1.10  0.341
2009 Park SR, Zan H, Pal Z, Zhang J, Al-Qahtani A, Pone EJ, Xu Z, Mai T, Casali P. HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nature Immunology. 10: 540-50. PMID 19363484 DOI: 10.1038/Ni.1725  0.36
2009 Zan H, Zhang J, Ardeshna S, Xu Z, Park SR, Casali P. Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination. Autoimmunity. 42: 89-103. PMID 19156553 DOI: 10.1080/08916930802629554  0.372
2008 Al-Qahtani A, Xu Z, Zan H, Walsh CM, Casali P. A role for DRAK2 in the germinal center reaction and the antibody response. Autoimmunity. 41: 341-52. PMID 18568639 DOI: 10.1080/08916930802170633  0.35
2007 Xu Z, Pone EJ, Al-Qahtani A, Park SR, Zan H, Casali P. Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Critical Reviews in Immunology. 27: 367-97. PMID 18197815 DOI: 10.1615/Critrevimmunol.V27.I4.60  0.39
2007 Xu Z, Zan H, Pal Z, Casali P. DNA replication to aid somatic hypermutation. Advances in Experimental Medicine and Biology. 596: 111-27. PMID 17338180 DOI: 10.1007/0-387-46530-8_10  0.352
2006 Casali P, Pal Z, Xu Z, Zan H. DNA repair in antibody somatic hypermutation. Trends in Immunology. 27: 313-21. PMID 16737852 DOI: 10.1016/J.It.2006.05.001  0.363
2006 Komori A, Xu Z, Wu X, Zan H, Casali P. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells. Molecular Immunology. 43: 1817-26. PMID 16412510 DOI: 10.1016/J.Molimm.2005.10.018  0.353
2005 Zan H, Shima N, Xu Z, Al-Qahtani A, Evinger Iii AJ, Zhong Y, Schimenti JC, Casali P. The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. The Embo Journal. 24: 3757-69. PMID 16222339 DOI: 10.1038/Sj.Emboj.7600833  0.349
2005 Xu Z, Fulop Z, Zhong Y, Evinger AJ, Zan H, Casali P. DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation. Annals of the New York Academy of Sciences. 1050: 146-62. PMID 16014529 DOI: 10.1196/Annals.1313.119  0.376
2004 Xu Z, Ou JH. Endogenous polymerase assay for the analysis of hepatitis B virus in transgenic mice. Methods in Molecular Medicine. 95: 295-302. PMID 14762312 DOI: 10.1385/1-59259-669-X:295  0.553
2003 Kojima H, Kaita KD, Xu Z, Ou JH, Gong Y, Zhang M, Minuk GY. The absence of up-regulation of telomerase activity during regeneration after partial hepatectomy in hepatitis B virus X gene transgenic mice. Journal of Hepatology. 39: 262-8. PMID 12873824 DOI: 10.1016/S0168-8278(03)00215-0  0.56
2003 Choi J, Xu Z, Ou JH. Triple decoding of hepatitis C virus RNA by programmed translational frameshifting. Molecular and Cellular Biology. 23: 1489-97. PMID 12588970 DOI: 10.1128/Mcb.23.5.1489-1497.2003  0.504
2003 Xu Z, Choi J, Lu W, Ou JH. Hepatitis C virus f protein is a short-lived protein associated with the endoplasmic reticulum. Journal of Virology. 77: 1578-83. PMID 12502871 DOI: 10.1128/Jvi.77.2.1578-1583.2003  0.501
2002 Li J, Xu Z, Zheng Y, Johnson DL, Ou JH. Regulation of hepatocyte nuclear factor 1 activity by wild-type and mutant hepatitis B virus X proteins. Journal of Virology. 76: 5875-81. PMID 12021320 DOI: 10.1128/Jvi.76.12.5875-5881.2002  0.552
2002 Xu Z, Yen TS, Wu L, Madden CR, Tan W, Slagle BL, Ou JH. Enhancement of hepatitis B virus replication by its X protein in transgenic mice. Journal of Virology. 76: 2579-84. PMID 11836439 DOI: 10.1128/Jvi.76.5.2579-2584.2002  0.559
2001 Xu Z, Choi J, Yen TS, Lu W, Strohecker A, Govindarajan S, Chien D, Selby MJ, Ou J. Synthesis of a novel hepatitis C virus protein by ribosomal frameshift. The Embo Journal. 20: 3840-8. PMID 11447125 DOI: 10.1093/Emboj/20.14.3840  0.34
1997 Buckwold VE, Xu Z, Yen TS, Ou JH. Effects of a frequent double-nucleotide basal core promoter mutation and its putative single-nucleotide precursor mutations on hepatitis B virus gene expression and replication. The Journal of General Virology. 78: 2055-65. PMID 9267007 DOI: 10.1099/0022-1317-78-8-2055  0.5
1996 Buckwold VE, Xu Z, Chen M, Yen TS, Ou JH. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. Journal of Virology. 70: 5845-51. PMID 8709203  0.51
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