Mariana Nikolova-Karakashian - Publications

Affiliations: 
Physiology University of Kentucky, Lexington, KY 
Area:
Biochemistry, Physiology Biology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Deevska G, Dotson PP, Mitov M, Butterfield DA, Nikolova-Karakashian M. Onset of Senescence and Steatosis in Hepatocytes as a Consequence of a Shift in the Diacylglycerol/Ceramide Balance at the Plasma Membrane. Cells. 10. PMID 34064003 DOI: 10.3390/cells10061278  0.31
2021 Nikolova-Karakashian M. Methods to Characterize Synthesis and Degradation of Sphingomyelin at the Plasma Membrane and Its Impact on Lipid Raft Dynamics. Methods in Molecular Biology (Clifton, N.J.). 2187: 113-129. PMID 32770504 DOI: 10.1007/978-1-0716-0814-2_7  0.307
2018 Zhong L, Kong JN, Dinkins MB, Leanhart S, Zhu Z, Spassieva SD, Qin H, Lin HP, Elsherbini A, Wang RR, Jiang X, Nikolova-Karakashian M, Wang G, Bieberich E. Increased liver tumor formation in neutral sphingomyelinase-2 deficient mice. Journal of Lipid Research. PMID 29567647 DOI: 10.1194/Jlr.M080879  0.328
2016 Shi L, Banerjee D, Dobierzewska A, Sabapathi S, Karakashian A, Giltiay N, Nikolova-Karakashian MN. Direct regulation of IGF Binding Protein 1 (IGFBP1) Promoter by Interleukin 1β via insulin- and FoxO-1 independent mechanism. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00289.2015. PMID 26884383 DOI: 10.1152/ajpendo.00289.2015  0.329
2016 Dobierzewska A, Astorga J, Limmer A, Palominos M, Deevska G, Nikolova-Karakashian M, Illanes SE. 37 Imbalance of bioactive sphingolipids rheostat in preeclampsia Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 6: 195-196. DOI: 10.1016/J.Preghy.2016.08.119  0.325
2015 Zhang LP, Kline RH, Deevska G, Ma F, Nikolova-Karakashian M, Westlund KN. Alcohol and high fat induced chronic pancreatitis: TRPV4 antagonist reduces hypersensitivity. Neuroscience. 311: 166-79. PMID 26480812 DOI: 10.1016/J.Neuroscience.2015.10.028  0.3
2014 Deevska G, Sunkara M, Karakashian C, Peppers B, Morris AJ, Nikolova-Karakashian MN. Effect of procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3. Journal of Lipid Research. 55: 2041-52. PMID 25047167 DOI: 10.1194/jlr.M048223  0.324
2014 Empinado HM, Deevska GM, Nikolova-Karakashian M, Yoo JK, Christou DD, Ferreira LF. Diaphragm dysfunction in heart failure is accompanied by increases in neutral sphingomyelinase activity and ceramide content. European Journal of Heart Failure. 16: 519-25. PMID 24596158 DOI: 10.1002/Ejhf.73  0.312
2014 Momchilova A, Petkova D, Staneva G, Markovska T, Pankov R, Skrobanska R, Nikolova-Karakashian M, Koumanov K. Resveratrol alters the lipid composition, metabolism and peroxide level in senescent rat hepatocytes. Chemico-Biological Interactions. 207: 74-80. PMID 24183824 DOI: 10.1016/J.Cbi.2013.10.016  0.376
2012 Dobierzewska A, Shi L, Karakashian AA, Nikolova-Karakashian MN. Interleukin 1β regulation of FoxO1 protein content and localization: evidence for a novel ceramide-dependent mechanism. The Journal of Biological Chemistry. 287: 44749-60. PMID 23105097 DOI: 10.1074/jbc.M112.378836  0.34
2011 Dobierzewska A, Giltiay NV, Sabapathi S, Karakashian AA, Nikolova-Karakashian MN. Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1beta. The Journal of Biological Chemistry. 286: 32064-73. PMID 21708940 DOI: 10.1074/jbc.M111.238030  0.347
2010 Nikolova-Karakashian MN, Rozenova KA. Ceramide in stress response. Advances in Experimental Medicine and Biology. 688: 86-108. PMID 20919648  0.748
2010 Rozenova KA, Deevska GM, Karakashian AA, Nikolova-Karakashian MN. Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor alpha (TNFalpha)-converting enzyme activity and TNFalpha secretion in macrophages. The Journal of Biological Chemistry. 285: 21103-13. PMID 20236926 DOI: 10.1074/jbc.M109.080671  0.722
2009 Deevska GM, Rozenova KA, Giltiay NV, Chambers MA, White J, Boyanovsky BB, Wei J, Daugherty A, Smart EJ, Reid MB, Merrill AH, Nikolova-Karakashian M. Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice. The Journal of Biological Chemistry. 284: 8359-68. PMID 19074137 DOI: 10.1074/Jbc.M807800200  0.712
2008 Nikolova-Karakashian M, Karakashian A, Rutkute K. Role of neutral sphingomyelinases in aging and inflammation. Sub-Cellular Biochemistry. 49: 469-86. PMID 18751923 DOI: 10.1007/978-1-4020-8831-5_18  0.743
2007 Rutkute K, Asmis RH, Nikolova-Karakashian MN. Regulation of neutral sphingomyelinase-2 by GSH: a new insight to the role of oxidative stress in aging-associated inflammation. Journal of Lipid Research. 48: 2443-52. PMID 17693623 DOI: 10.1194/Jlr.M700227-Jlr200  0.758
2007 Rutkute K, Karakashian AA, Giltiay NV, Dobierzewska A, Nikolova-Karakashian MN. Aging in rat causes hepatic hyperresposiveness to interleukin-1beta which is mediated by neutral sphingomyelinase-2. Hepatology (Baltimore, Md.). 46: 1166-76. PMID 17668873 DOI: 10.1002/Hep.21777  0.752
2007 Rutkute K, Nikolova-Karakashian MN. Regulation of insulin-like growth factor binding protein-1 expression during aging. Biochemical and Biophysical Research Communications. 361: 263-9. PMID 17645865 DOI: 10.1016/J.Bbrc.2007.06.079  0.746
2006 Li XA, Guo L, Asmis R, Nikolova-Karakashian M, Smart EJ. Scavenger receptor BI prevents nitric oxide-induced cytotoxicity and endotoxin-induced death. Circulation Research. 98: e60-5. PMID 16574909 DOI: 10.1161/01.Res.0000219310.00308.10  0.353
2005 Giltiay NV, Karakashian AA, Alimov AP, Ligthle S, Nikolova-Karakashian MN. Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1beta in hepatocytes. Journal of Lipid Research. 46: 2497-505. PMID 16106045 DOI: 10.1194/jlr.M500337-JLR200  0.451
2005 Sathishkumar S, Boyanovsky B, Karakashian AA, Rozenova K, Giltiay NV, Kudrimoti M, Mohiuddin M, Ahmed MM, Nikolova-Karakashian M. Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: implications for endothelial apoptosis. Cancer Biology & Therapy. 4: 979-86. PMID 16096366 DOI: 10.4161/Cbt.4.9.1915  0.711
2004 Karakashian AA, Giltiay NV, Smith GM, Nikolova-Karakashian MN. Expression of neutral sphingomyelinase-2 (NSMase-2) in primary rat hepatocytes modulates IL-β-induced JNK activation Faseb Journal. 18: 968-970. PMID 15059969 DOI: 10.1096/fj.03-0875fje  0.469
2003 Lightle S, Tosheva R, Lee A, Queen-Baker J, Boyanovsky B, Shedlofsky S, Nikolova-Karakashian M. Elevation of ceramide in serum lipoproteins during acute phase response in humans and mice: role of serine-palmitoyl transferase. Archives of Biochemistry and Biophysics. 419: 120-8. PMID 14592455 DOI: 10.1016/J.Abb.2003.08.031  0.368
2002 Deaciuc I, D'Souza N, Nikolova-Karakashian M, de Villiers W, Sarphie T, Hill D, McClain C. The regulation of Fas (CD95/Apo-1)-mediated liver apoptosis in Kupffer cell-depleted mice. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 24: 192. PMID 12270749 DOI: 10.1016/S1386-6346(02)00021-9  0.377
2002 Li XA, Titlow WB, Jackson BA, Giltiay N, Nikolova-Karakashian M, Uittenbogaard A, Smart EJ. High density lipoprotein binding to scavenger receptor, Class B, type I activates endothelial nitric-oxide synthase in a ceramide-dependent manner. The Journal of Biological Chemistry. 277: 11058-63. PMID 11792700 DOI: 10.1074/Jbc.M110985200  0.327
2001 Lightle SA, Oakley JI, Nikolova-Karakashian MN. Activation of sphingolipid turnover and chronic generation of ceramide and sphingosine in liver during aging. Mechanisms of Ageing and Development. 120: 111-25. PMID 11087909 DOI: 10.1016/S0047-6374(00)00191-3  0.391
2000 Yu ZF, Nikolova-Karakashian M, Zhou D, Cheng G, Schuchman EH, Mattson MP. Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis Journal of Molecular Neuroscience. 15: 85-97. PMID 11220788 DOI: 10.1385/Jmn:15:2:85  0.306
1999 Merrill AH, Nikolova-Karakashian M, Schmelz EM, Morgan ET, Stewart J. Regulation of cytochrome P450 expression by sphingolipids Chemistry and Physics of Lipids. 102: 131-139. PMID 11001567 DOI: 10.1016/S0009-3084(99)00081-X  0.388
1999 Nikolova-Karakashian M. Assays for the biosynthesis of sphingomyelin and ceramide phosphoethanolamine. Methods in Enzymology. 311: 31-42. PMID 10563308 DOI: 10.1016/S0076-6879(00)11064-X  0.326
1999 Augé N, Nikolova-Karakashian M, Carpentier S, Parthasarathy S, Nègre-Salvayre A, Salvayre R, Merrill AH, Levade T. Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase. The Journal of Biological Chemistry. 274: 21533-8. PMID 10419457 DOI: 10.1074/Jbc.274.31.21533  0.358
1997 Nikolova-Karakashian M, Morgan ET, Alexander C, Liotta DC, Merrill AH. Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome P450 2C11 (CYP2C11) Journal of Biological Chemistry. 272: 18718-18724. PMID 9228043 DOI: 10.1074/Jbc.272.30.18718  0.552
1996 Morgan ET, Nikolova-Karakashian M, Chen JQ, Merrill AH. Sphingolipid-dependent signaling in regulation of cytochrome P450 expression Methods in Enzymology. 272: 381-388. PMID 8791797 DOI: 10.1016/S0076-6879(96)72043-8  0.383
1995 Merrill AH, Lingrell S, Wang E, Nikolova-Karakashian M, Vales TR, Vance DE. Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein secretion. The Journal of Biological Chemistry. 270: 13834-41. PMID 7775441 DOI: 10.1074/Jbc.270.23.13834  0.355
1995 Chen J, Nikolova-Karakashian M, Merrill AH, Morgan ET. Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes Journal of Biological Chemistry. 270: 25233-25238. PMID 7559661 DOI: 10.1074/Jbc.270.42.25233  0.381
1993 Gavrilova NJ, Setchenska MS, Nikolova-Karakashian M, Petkova DH. Effect of a sunflower oil-supplemented diet on protein kinase activities of rat liver plasma membranes. The International Journal of Biochemistry. 24: 1953-8. PMID 1473608 DOI: 10.1016/0020-711X(92)90291-8  0.337
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