Frederick E. Domann - Publications

Affiliations: 
Free Radical and Radiation Biology University of Iowa, Iowa City, IA 
Area:
Molecular Biology, Biochemistry, Oncology

178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Steers GJ, O'Leary BR, Du J, Wagner BA, Carroll RS, Domann FE, Goswami PC, Buettner GR, Cullen JJ. Pharmacologic Ascorbate and DNMT Inhibitors Increase DUOX Expression and Peroxide-Mediated Toxicity in Pancreatic Cancer. Antioxidants (Basel, Switzerland). 12. PMID 37759986 DOI: 10.3390/antiox12091683  0.338
2021 O'Leary BR, Carroll RS, Steers GJ, Hrabe J, Domann FE, Cullen JJ. Impact of EcSOD Perturbations in Cancer Progression. Antioxidants (Basel, Switzerland). 10. PMID 34439467 DOI: 10.3390/antiox10081219  0.327
2021 Domann FE, Hitchler MJ. Aberrant redox biology and epigenetic reprogramming: Co-conspirators across multiple human diseases. Free Radical Biology & Medicine. PMID 33932538 DOI: 10.1016/j.freeradbiomed.2021.04.020  0.768
2021 Domann FE, Hitchler MJ. Introduction to the special issue on 'epigenetics and redox signaling'. Free Radical Biology & Medicine. PMID 33862159 DOI: 10.1016/j.freeradbiomed.2021.04.015  0.708
2021 Hitchler MJ, Domann FE. The epigenetic and morphogenetic effects of molecular oxygen and its derived reactive species in development. Free Radical Biology & Medicine. PMID 33450377 DOI: 10.1016/j.freeradbiomed.2021.01.008  0.763
2020 Cramer-Morales KL, Heer CD, Mapuskar KA, Domann FE. Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate. Journal of Experimental Pathology. 1: 60-70. PMID 33585836  0.317
2020 Place TL, Domann FE, Case AJ. Corrigendum to "Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research" [Free Radic. Biol. Med. 113 (2017) 311-322]. Free Radical Biology & Medicine. PMID 32736953 DOI: 10.1016/J.Freeradbiomed.2020.07.016  0.611
2017 Golden BO, Griess B, Mir S, Fitzgerald M, Kuperwasser C, Domann F, Teoh-Fitzgerald M. Extracellular superoxide dismutase inhibits hepatocyte growth factor-mediated breast cancer-fibroblast interactions. Oncotarget. 8: 107390-107408. PMID 29296173 DOI: 10.18632/Oncotarget.22379  0.396
2017 Place TL, Domann FE, Case AJ. Limitations of Oxygen Delivery to Cells in Culture: An Underappreciated Problem in Basic and Translational Research. Free Radical Biology & Medicine. PMID 29032224 DOI: 10.1016/J.Freeradbiomed.2017.10.003  0.627
2017 Griess B, Tom E, Domann F, Teoh-Fitzgerald M. Extracellular Superoxide Dismutase and its Role in Cancer. Free Radical Biology & Medicine. PMID 28842347 DOI: 10.1016/J.Freeradbiomed.2017.08.013  0.429
2017 Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, ... ... Domann FE, et al. O2(⋅-) and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer Cell. 32: 268. PMID 28810149 DOI: 10.1016/J.Ccell.2017.07.008  0.316
2017 Mapuskar KA, Flippo KH, Schoenfeld JD, Riley DP, Strack S, Abu-Hejleh T, Furqan M, Monga V, Domann FE, Buatti JM, Goswami PC, Spitz DR, Allen BG. Mitochondrial superoxide increases age-associated susceptibility of human dermal fibroblasts to radiation and chemotherapy. Cancer Research. PMID 28765155 DOI: 10.1158/0008-5472.Can-17-0106  0.327
2017 Ekoue DN, Bera S, Ansong E, Hart PC, Zaichick S, Domann FE, Bonini MG, Diamond AM. Allele specific interaction between glutathione peroxidase 1 and manganese superoxide dismutase affects the levels of Bcl-2, Sirt3 and E-Cadherin. Free Radical Research. 1-27. PMID 28587495 DOI: 10.1080/10715762.2017.1339303  0.405
2017 Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, ... ... Domann FE, et al. O2(⋅-) and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer Cell. PMID 28366679 DOI: 10.1016/J.Ccell.2017.02.018  0.371
2016 Gómez-Contreras P, Ramiro-Díaz JM, Sierra A, Stipp C, Domann FE, Weigel RJ, Lal G. Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPases. Clinical & Experimental Metastasis. 34: 37-49. PMID 27770373 DOI: 10.1007/S10585-016-9827-5  0.379
2016 Nozik-Grayck E, Woods C, Stearman RS, Venkataraman S, Ferguson BS, Swain K, Bowler RP, Geraci MW, Ihida-Stansbury K, Stenmark KR, McKinsey TA, Domann FE. Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00263.2015. PMID 27233998 DOI: 10.1152/Ajplung.00263.2015  0.405
2016 Christensen DK, Armaiz-Pena GN, Ramirez E, Matsuo K, Zimmerman B, Zand B, Shinn E, Goodheart MJ, Bender D, Thaker PH, Ahmed A, Penedo FJ, DeGeest K, Mendez L, Domann F, et al. SSRI use and clinical outcomes in epithelial ovarian cancer. Oncotarget. PMID 27121207 DOI: 10.18632/Oncotarget.8891  0.338
2016 Xiao W, Sarsour EH, Wagner BA, Doskey CM, Buettner GR, Domann FE, Goswami PC. Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes. Archives of Toxicology. 90: 319-32. PMID 25417049 DOI: 10.1007/S00204-014-1407-3  0.382
2016 Salinas E, Wernimont S, TenNapel M, Domann F, Neff T, Gonzalez-Bosquet J, Goodheart M. Association analysis of oxidative stress–related genes and endometrial cancer in The Cancer Genome Atlas Gynecologic Oncology. 141: 189. DOI: 10.1016/J.Ygyno.2016.04.488  0.33
2016 Cramer-Morales K, Mapuskar K, Heer C, Domann F. Succinate Is a Mitochondrial Retrograde Signal That Links MnSOD Depletion to Loss of Epigenetic Control and Aberrant Genomic DNA Methylation Free Radical Biology and Medicine. 100: S38. DOI: 10.1016/J.Freeradbiomed.2016.10.098  0.436
2015 Cramer-Morales K, Heer CD, Mapuskar KA, Domann FE. SOD2 targeted gene editing by CRISPR/Cas9 yields Human cells devoid of MnSOD. Free Radical Biology & Medicine. 89: 379-86. PMID 26208779 DOI: 10.1016/J.Freeradbiomed.2015.07.017  0.396
2015 Hrabe JE, O'Leary BR, Fath MA, Rodman SN, Button AM, Domann FE, Spitz DR, Mezhir JJ. Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells. Redox Biology. 5: 319-327. PMID 26114584 DOI: 10.1016/J.Redox.2015.06.004  0.383
2015 Jiménez-Chillarón JC, Nijland MJ, Ascensão AA, Sardão VA, Magalhães J, Hitchler MJ, Domann FE, Oliveira PJ. Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling. Epigenetics : Official Journal of the Dna Methylation Society. 10: 259-73. PMID 25774863 DOI: 10.1080/15592294.2015.1020267  0.763
2015 Park JM, Wu T, Cyr AR, Woodfield GW, De Andrade JP, Spanheimer PM, Li T, Sugg SL, Lal G, Domann FE, Zhang W, Weigel RJ. The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis. Oncogene. PMID 25772240 DOI: 10.1038/Onc.2015.59  0.769
2015 Duangmano S, Sae-Lim P, Suksamrarn A, Patmasiriwat P, Domann FE. Corrigendum to "Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest". Journal of Oncology. 2015: 486850. PMID 25722721 DOI: 10.1155/2015/486850  0.322
2015 Xiao W, Son J, Vorrink SU, Domann FE, Goswami PC. Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicology Letters. 233: 258-66. PMID 25668756 DOI: 10.1016/J.Toxlet.2015.02.005  0.783
2015 O'Leary BR, Fath MA, Bellizzi AM, Hrabe JE, Button AM, Allen BG, Case AJ, Altekruse S, Wagner BA, Buettner GR, Lynch CF, Hernandez BY, Cozen W, Beardsley RA, Keene J, ... ... Domann FE, et al. Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1741-51. PMID 25634994 DOI: 10.1158/1078-0432.Ccr-14-1959  0.667
2015 Cyr AR, Kulak MV, Park JM, Bogachek MV, Spanheimer PM, Woodfield GW, White-Baer LS, O'Malley YQ, Sugg SL, Olivier AK, Zhang W, Domann FE, Weigel RJ. TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis. Oncogene. 34: 436-44. PMID 24469049 DOI: 10.1038/Onc.2013.569  0.76
2015 Mezhir JJ, O'Leary BR, Bellizzi AM, Altekruse S, Lynch CF, Hernandez BY, Cozen W, Henry MD, Keene J, Beardsley RA, Spitz DR, Domann FE. Abstract B52: The role of extracellular superoxide dismutase activity in pancreatic cancer biology and therapy Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B52  0.423
2015 Cramer-Morales K, Schoenfeld J, Allen B, Domann F. Deletion of SOD2 Perturbs Iron Homeostasis and Induces Photosensitivity in a Human Erythroid Cell Line Free Radical Biology and Medicine. 87: S128. DOI: 10.1016/J.Freeradbiomed.2015.10.333  0.31
2014 Hallberg AR, Vorrink SU, Hudachek DR, Cramer-Morales K, Milhem MM, Cornell RA, Domann FE. Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma. Epigenetics. 9: 1641-7. PMID 25625848 DOI: 10.4161/15592294.2014.988062  0.779
2014 Yang S, Jia Y, Liu X, Winters C, Wang X, Zhang Y, Devor EJ, Hovey AM, Reyes HD, Xiao X, Xu Y, Dai D, Meng X, Thiel KW, Domann FE, et al. Systematic dissection of the mechanisms underlying progesterone receptor downregulation in endometrial cancer. Oncotarget. 5: 9783-97. PMID 25229191 DOI: 10.18632/Oncotarget.2392  0.399
2014 Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, et al. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environmental Health Perspectives. 122: 1271-8. PMID 25127496 DOI: 10.1289/Ehp.1408418  0.346
2014 Vorrink SU, Hudachek DR, Domann FE. Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). International Journal of Molecular Sciences. 15: 13916-31. PMID 25116688 DOI: 10.3390/Ijms150813916  0.794
2014 Wegman-Points LJ, Teoh-Fitzgerald ML, Mao G, Zhu Y, Fath MA, Spitz DR, Domann FE. Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population. Redox Biology. 2: 847-54. PMID 25009786 DOI: 10.1016/J.Redox.2014.06.006  0.405
2014 Vorrink SU, Sarsour EH, Olivier AK, Robertson LW, Goswami PC, Domann FE. PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 377-82. PMID 24916446 DOI: 10.1016/J.Etp.2014.05.005  0.761
2014 Vorrink SU, Domann FE. Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node. Chemico-Biological Interactions. 218: 82-8. PMID 24824450 DOI: 10.1016/J.Cbi.2014.05.001  0.754
2014 Hall DD, Wu Y, Domann FE, Spitz DR, Anderson ME. Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival. Plos One. 9: e96866. PMID 24802861 DOI: 10.1371/Journal.Pone.0096866  0.41
2014 Case AJ, Domann FE. Absence of manganese superoxide dismutase delays p53-induced tumor formation. Redox Biology. 2: 220-3. PMID 24494196 DOI: 10.1016/J.Redox.2014.01.001  0.668
2014 Gross TJ, Kremens K, Powers LS, Brink B, Knutson T, Domann FE, Philibert RA, Milhem MM, Monick MM. Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses. Journal of Immunology (Baltimore, Md. : 1950). 192: 2326-38. PMID 24477906 DOI: 10.4049/Jimmunol.1301758  0.355
2014 Vorrink SU, Severson PL, Kulak MV, Futscher BW, Domann FE. Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicology and Applied Pharmacology. 274: 408-16. PMID 24355420 DOI: 10.1016/J.Taap.2013.12.002  0.784
2014 Zhou B, Gibson-Corley KN, Herndon ME, Sun Y, Gustafson-Wagner E, Teoh-Fitzgerald M, Domann FE, Henry MD, Stipp CS. Integrin α3β1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma. Molecular Cancer Research : McR. 12: 143-54. PMID 24002891 DOI: 10.1158/1541-7786.Mcr-13-0184  0.347
2014 Hitchler MJ, Domann FE. Regulation of CuZnSOD and its redox signaling potential: implications for amyotrophic lateral sclerosis. Antioxidants & Redox Signaling. 20: 1590-8. PMID 23795822 DOI: 10.1089/Ars.2013.5385  0.729
2014 Teoh-Fitzgerald ML, Fitzgerald MP, Zhong W, Askeland RW, Domann FE. Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis. Oncogene. 33: 358-68. PMID 23318435 DOI: 10.1038/Onc.2012.582  0.445
2014 Park JM, Wu T, Woodfield G, Cyr A, Andrade JD, Zhang W, Domann F, Weigel RJ. Abstract 3914: Tcfap2c regulates growth and oncogenesis in neu-activated breast cancer Cancer Research. 74: 3914-3914. DOI: 10.1158/1538-7445.Am2014-3914  0.762
2014 Cyr AR, Kulak MV, Park JM, Bogachek MV, Spanheimer PM, Woodfield GW, White-Baer LS, O'Malley YQ, Sugg SL, Olivier AK, Zhang W, Domann FE, Weigel RJ. TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis Oncogene. DOI: 10.1038/onc.2013.569  0.746
2014 Heer C, Morales K, Hudachek D, Domann F. Direct and Complete Genetic Disruption of SOD2 in Human Cells Using the CRISPR/Cas9 System for Gene Editing Free Radical Biology and Medicine. 76: S32. DOI: 10.1016/J.Freeradbiomed.2014.10.445  0.347
2014 Woods C, Venkataraman S, Stearman R, Mouradian G, Villegas L, Bowler R, McKinsey T, Ferguson B, Ihida-Stansbury K, Geraci M, Stenmark K, Domann F, Nozik-Grayck E. Regulation of Aberrant Expression of EC-SOD in Human IPAH by Epigenetic Mechanisms Free Radical Biology and Medicine. 76: S165. DOI: 10.1016/J.Freeradbiomed.2014.10.052  0.402
2013 Place TL, Domann FE. Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein. Hypoxia. 2013: 13-17. PMID 24672806 DOI: 10.2147/Hp.S50091  0.397
2013 Place TL, Nauseef JT, Peterson MK, Henry MD, Mezhir JJ, Domann FE. Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition. Plos One. 8: e83021. PMID 24367580 DOI: 10.1371/Journal.Pone.0083021  0.46
2013 Cyr AR, Brown KE, McCormick ML, Coleman MC, Case AJ, Watts GS, Futscher BW, Spitz DR, Domann FE. Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes. Redox Biology. 1: 172-7. PMID 24024150 DOI: 10.1016/J.Redox.2013.01.001  0.789
2013 Khoo NK, Hebbar S, Zhao W, Moore SA, Domann FE, Robbins ME. Differential activation of catalase expression and activity by PPAR agonists: implications for astrocyte protection in anti-glioma therapy. Redox Biology. 1: 70-9. PMID 24024139 DOI: 10.1016/J.Redox.2012.12.006  0.372
2013 Lal G, Contreras PG, Kulak M, Woodfield G, Bair T, Domann FE, Weigel RJ. Human Melanoma cells over-express extracellular matrix 1 (ECM1) which is regulated by TFAP2C. Plos One. 8: e73953. PMID 24023917 DOI: 10.1371/Journal.Pone.0073953  0.393
2013 Sobhakumari A, Schickling BM, Love-Homan L, Raeburn A, Fletcher EV, Case AJ, Domann FE, Miller FJ, Simons AL. NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells. Toxicology and Applied Pharmacology. 272: 736-45. PMID 23917044 DOI: 10.1016/J.Taap.2013.07.013  0.676
2013 Case AJ, Madsen JM, Motto DG, Meyerholz DK, Domann FE. Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells. Free Radical Biology & Medicine. 56: 17-27. PMID 23219873 DOI: 10.1016/J.Freeradbiomed.2012.11.018  0.676
2013 Kulak MV, Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T, Price DH, Domann FE, Weigel RJ. Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer. Oncogene. 32: 4043-51. PMID 22964634 DOI: 10.1038/Onc.2012.400  0.78
2013 Cyr AR, Hitchler MJ, Domann FE. Regulation of SOD2 in cancer by histone modifications and CpG methylation: closing the loop between redox biology and epigenetics. Antioxidants & Redox Signaling. 18: 1946-55. PMID 22946823 DOI: 10.1089/Ars.2012.4850  0.804
2013 Gomez-Contreras P, Domann F, Weigel R, Lal G. Abstract P5-04-16: Extracellular matrix 1 (ECM1) knockdown alters cellular characteristics, CD44 expression and other metastasis associated genes in breast cancer cells Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P5-04-16  0.405
2013 Hrabe J, Domann F, Spitz D, Mezhir J. Inhibition of TAK1 Decreases Colon Cancer Cell Survival by Thiol-dependent Oxidative Stress Journal of Surgical Research. 179: 250. DOI: 10.1016/J.Jss.2012.10.471  0.33
2013 O'Leary B, Bellizzi A, Domann F, Mezhir J. Extracellular Superoxide Dismutase (EcSOD) Expression in Pancreatic Adenocarcinoma Journal of Surgical Research. 179: 241. DOI: 10.1016/J.Jss.2012.10.449  0.326
2013 O'Leary B, Hrabe JE, Henry MD, Domann FE, Mezhir JJ. Extracellular superoxide dismutase reduces pancreatic cancer invasion and metastasis Journal of the American College of Surgeons. 217: S128. DOI: 10.1016/J.Jamcollsurg.2013.07.296  0.317
2013 Case AJ, O'Leary BR, Stipp CS, Domann FE, Mezhir JJ. Catalytically Inactive Extracellular Superoxide Dismutase Reduces Pancreatic Tumor Cell Invasion Free Radical Biology and Medicine. 65: S16. DOI: 10.1016/J.Freeradbiomed.2013.10.417  0.634
2012 Case AJ, Mezhir JJ, O'Leary BR, Hrabe JE, Domann FE. Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase. Redox Report : Communications in Free Radical Research. 17: 239-45. PMID 23339859 DOI: 10.1179/1351000212Y.0000000028  0.627
2012 Duangmano S, Sae-Lim P, Suksamrarn A, Domann FE, Patmasiriwat P. Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation. Bmc Complementary and Alternative Medicine. 12: 185. PMID 23062075 DOI: 10.1186/1472-6882-12-185  0.316
2012 Hitchler MJ, Domann FE. Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome. Free Radical Biology & Medicine. 53: 2178-87. PMID 23022407 DOI: 10.1016/J.Freeradbiomed.2012.09.028  0.771
2012 Case AJ, Domann FE. Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland. Free Radical Research. 46: 1361-8. PMID 22834911 DOI: 10.3109/10715762.2012.715370  0.671
2012 Duangmano S, Sae-Lim P, Suksamrarn A, Patmasiriwat P, Domann FE. Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest. Journal of Oncology. 2012: 601682. PMID 22690217 DOI: 10.1155/2012/601682  0.356
2012 Teoh-Fitzgerald ML, Fitzgerald MP, Jensen TJ, Futscher BW, Domann FE. Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis. Molecular Cancer Research : McR. 10: 40-51. PMID 22064654 DOI: 10.1158/1541-7786.Mcr-11-0501  0.37
2012 Muniz VP, Zhang X, Reed SM, Tompkins VS, Smith T, Hagen JK, Fitzgerald M, Button A, Smith B, Zamba KD, Domann FE, Mezhir JJ, Weydert J, Askeland RA, Quelle DE. Abstract 712: Parf-1A (Partner of ARF isoform 1A) promotes oxaliplatin resistance and is a new prognostic marker of survival in pancreatic ductal adenocarcinoma Cancer Research. 72: 712-712. DOI: 10.1158/1538-7445.Am2012-712  0.305
2012 Hrabe JE, Case AJ, O'Leary BR, Place TL, Olivier AK, Henry MD, Domann FE, Mezhir JJ. Extracellular superoxide dismutase promotes pancreatic cancer liver metastasis Journal of the American College of Surgeons. 215: S131. DOI: 10.1016/J.Jamcollsurg.2012.06.338  0.637
2012 Diers AR, Fitzgerald MP, Keszler A, Domann FE, Hogg N. Modulation of Cellular Bioenergetics by INOSDerived Nitric Oxide in Breast Cancer: Effects on Epigenetic Control of maspin Expression Free Radical Biology and Medicine. 53: S41. DOI: 10.1016/J.Freeradbiomed.2012.10.105  0.368
2012 Case AJ, Madsen JM, Motto DG, Meyerholz DK, Domann FE. Disruption of Mitochondrial Superoxide Flux Causes Abnormal Heme Synthesis and Hemoglobin Gene Regulation in Erythroid Precursor Cells Free Radical Biology and Medicine. 53: S17. DOI: 10.1016/J.Freeradbiomed.2012.10.035  0.661
2011 Yue WY, Clark JJ, Fernando A, Domann F, Hansen MR. Contribution of persistent C-Jun N-terminal kinase activity to the survival of human vestibular schwannoma cells by suppression of accumulation of mitochondrial superoxides. Neuro-Oncology. 13: 961-73. PMID 21697181 DOI: 10.1093/Neuonc/Nor068  0.365
2011 Fitzgerald MP, Gourronc F, Teoh ML, Provenzano MJ, Case AJ, Martin JA, Domann FE. Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis. Sarcoma. 2011: 598218. PMID 21559267 DOI: 10.1155/2011/598218  0.695
2011 Tang X, Sun Z, Runne C, Madsen J, Domann F, Henry M, Lin F, Chen S. A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer. The Journal of Biological Chemistry. 286: 13244-54. PMID 21349837 DOI: 10.1074/Jbc.M110.206615  0.335
2011 Place TL, Fitzgerald MP, Venkataraman S, Vorrink SU, Case AJ, Teoh ML, Domann FE. Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. Plos One. 6: e14617. PMID 21297970 DOI: 10.1371/Journal.Pone.0014617  0.812
2011 Aykin-Burns N, Slane BG, Liu AT, Owens KM, O'Malley MS, Smith BJ, Domann FE, Spitz DR. Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species. Radiation Research. 175: 150-8. PMID 21268708 DOI: 10.1667/Rr2220.1  0.342
2011 Case AJ, McGill JL, Tygrett LT, Shirasawa T, Spitz DR, Waldschmidt TJ, Legge KL, Domann FE. Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge. Free Radical Biology & Medicine. 50: 448-58. PMID 21130157 DOI: 10.1016/J.Freeradbiomed.2010.11.025  0.64
2011 Cyr AR, Domann FE. The redox basis of epigenetic modifications: from mechanisms to functional consequences. Antioxidants & Redox Signaling. 15: 551-89. PMID 20919933 DOI: 10.1089/Ars.2010.3492  0.74
2011 Mao G, Jacobus J, Martin S, Case A, Aykin-Burns N, Mapuskar K, Coleman MC, Knudson MC, Gius D, Domann F, Spitz DR. Sirtuin 3−/−Thymocytes Demonstrate Increased Levels of Superoxide, a Diminished Radiation-Induced Adaptive Response, and Accelerated Bax-Induced Thymic Lymphoma in the C57BL/6 mice Free Radical Biology and Medicine. 51: S125-S126. DOI: 10.1016/J.Freeradbiomed.2011.10.328  0.607
2011 Fletcher EV, Sobhakumari A, Brown CO, Case AJ, Spitz DR, Domann FE, Goel A, Simons AL. EGFR Inhibition Induces IL6 Expression Via NOX4 in Head and Neck Cancer Cells Free Radical Biology and Medicine. 51: S133-S134. DOI: 10.1016/J.Freeradbiomed.2011.10.278  0.642
2010 Drake JM, Barnes JM, Madsen JM, Domann FE, Stipp CS, Henry MD. ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells. The Journal of Biological Chemistry. 285: 33940-8. PMID 20729552 DOI: 10.1074/Jbc.M110.136044  0.395
2010 Fitzgerald MP, Madsen JM, Coleman MC, Teoh ML, Westphal SG, Spitz DR, Radi R, Domann FE. Transgenic biosynthesis of trypanothione protects Escherichia coli from radiation-induced toxicity. Radiation Research. 174: 290-6. PMID 20726720 DOI: 10.1667/Rr2235.1  0.315
2010 Woodfield GW, Chen Y, Bair TB, Domann FE, Weigel RJ. Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes, Chromosomes & Cancer. 49: 948-62. PMID 20629094 DOI: 10.1002/Gcc.20807  0.39
2010 Teoh ML, Fitzgerald MP, Domann FE. Abstract 3373: Overexpression of EcSOD-ΔHBD suppresses breast cancer metastasis Cancer Research. 70: 3373-3373. DOI: 10.1158/1538-7445.Am10-3373  0.362
2010 Fitzgerald MP, Teoh ML, Madsen JM, Domann FE. Abstract 2285: Epigenetic silencing of SOD3 contributes to the malignant phenotype in human lung cancer Cancer Research. 70: 2285-2285. DOI: 10.1158/1538-7445.Am10-2285  0.42
2010 Cyr AR, Case AJ, Mao G, Domann FE. Conditional Knockout of Sod2 in Murine Hepatocytes Disrupts Epigenetic Control of Gene Expression Free Radical Biology and Medicine. 49: S128. DOI: 10.1016/J.Freeradbiomed.2010.10.351  0.795
2010 Case AJ, Domann FE. A Novel Role for Mitochondrial Superoxide in the Development of Erythropoietic Protoporphyria Free Radical Biology and Medicine. 49: S92. DOI: 10.1016/J.Freeradbiomed.2010.10.234  0.604
2010 Wegman LJ, Oberley LW, Domann FE. Overexpression of MnSOD Increases the Self-renewal Capacity of Human Breast Cancer Cells Free Radical Biology and Medicine. 49: S73. DOI: 10.1016/J.Freeradbiomed.2010.10.182  0.338
2010 Teoh M, Fitzgerald M, Zhong W, Domann F. Acinar Morphogenesis of Human Mammary Epithelial Cells in 3D Culture Induces EcSOD Expression via Epigenetic Reprogramming Free Radical Biology and Medicine. 49: S72. DOI: 10.1016/J.Freeradbiomed.2010.10.178  0.369
2010 Mao G, Jacobus JA, Martin SM, Case AJ, Aykin-Burns N, Mapuskar K, Coleman MC, Gius D, Domann FE, Spitz DR. Low Dose (10-100cGy) Whole Body Irradiation Increases Steady-state Levels of Superoxide in C57BL/6 Thymocytes Free Radical Biology and Medicine. 49: S66. DOI: 10.1016/J.Freeradbiomed.2010.10.158  0.585
2010 Aykin-Burns N, Zhu Y, Cyr AR, Klingelhutz AJ, Domann FE. Exploring the Role of Cancer Cell Mitochondria in Malignant Phenotype Free Radical Biology and Medicine. 49: S54. DOI: 10.1016/J.Freeradbiomed.2010.10.121  0.736
2010 Fitzgerald MP, Teoh-Fitzgerald LT, Jensen TJ, Domann FE. Epigenetic Silencing of EcSOD Promotes the Invasive Phenotype in Human Lung Cancer Free Radical Biology and Medicine. 49: S46. DOI: 10.1016/J.Freeradbiomed.2010.10.098  0.345
2009 Yu L, Hitchler MJ, Sun W, Sarsour EH, Goswami PC, Klingelhutz AJ, Domann FE. AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes. Journal of Oncology. 2009: 780874. PMID 20066163 DOI: 10.1155/2009/780874  0.758
2009 Dayal D, Martin SM, Owens KM, Aykin-Burns N, Zhu Y, Boominathan A, Pain D, Limoli CL, Goswami PC, Domann FE, Spitz DR. Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation. Radiation Research. 172: 737-45. PMID 19929420 DOI: 10.1667/Rr1617.1  0.327
2009 Sinthupibulyakit C, Grimes KR, Domann FE, Xu Y, Fang F, Ittarat W, St Clair DK, St Clair W. p53 is an important factor for the radiosensitization effect of 2-deoxy-D-glucose. International Journal of Oncology. 35: 609-15. PMID 19639181 DOI: 10.3892/Ijo_00000372  0.339
2009 Teoh ML, Fitzgerald MP, Oberley LW, Domann FE. Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion. Cancer Research. 69: 6355-63. PMID 19602586 DOI: 10.1158/0008-5472.Can-09-1195  0.412
2009 Woodfield GW, Hitchler MJ, Chen Y, Domann FE, Weigel RJ. Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3672-9. PMID 19458056 DOI: 10.1158/1078-0432.Ccr-08-2343  0.762
2009 Hitchler MJ, Domann FE. Metabolic defects provide a spark for the epigenetic switch in cancer. Free Radical Biology & Medicine. 47: 115-27. PMID 19362589 DOI: 10.1016/J.Freeradbiomed.2009.04.010  0.789
2009 Case AJ, Wagner BA, Buettner GR, Domann FE. Deficiency of MnSOD in Hematopoietic Stem Cells Causes a Sideroblastic Anemia-Like Phenotype. Blood. 114: 1991-1991. DOI: 10.1182/Blood.V114.22.1991.1991  0.652
2009 Case AJ, Mcgill JL, Sangster SC, Madsen JM, Tygrett LT, Johns AG, Takahashi T, Shirasawa T, Spitz DR, Meyerholz DK, Waldschmidt TJ, Legge KL, Domann FE. Heightened Susceptibility to Influenza Mortality in Immunodeficient Mice Caused by a T-Cell Specific Defect in SOD2. Blood. 114: 1655-1655. DOI: 10.1182/Blood.V114.22.1655.1655  0.622
2008 Hitchler MJ, Oberley LW, Domann FE. Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. Free Radical Biology & Medicine. 45: 1573-80. PMID 18845242 DOI: 10.1016/J.Freeradbiomed.2008.09.005  0.787
2008 Rahimov F, Marazita ML, Visel A, Cooper ME, Hitchler MJ, Rubini M, Domann FE, Govil M, Christensen K, Bille C, Melbye M, Jugessur A, Lie RT, Wilcox AJ, Fitzpatrick DR, et al. Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip. Nature Genetics. 40: 1341-7. PMID 18836445 DOI: 10.1038/Ng.242  0.726
2008 Watts GS, Futscher BW, Holtan N, Degeest K, Domann FE, Rose SL. DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage. Bmc Medical Genomics. 1: 47. PMID 18826610 DOI: 10.1186/1755-8794-1-47  0.386
2008 Lal G, Padmanabha L, Provenzano M, Fitzgerald M, Weydert J, Domann FE. Regulation of 14-3-3sigma expression in human thyroid carcinoma is epigenetically regulated by aberrant cytosine methylation. Cancer Letters. 267: 165-74. PMID 18440129 DOI: 10.1016/J.Canlet.2008.03.017  0.399
2008 Dong LF, Low P, Dyason JC, Wang XF, Prochazka L, Witting PK, Freeman R, Swettenham E, Valis K, Liu J, Zobalova R, Turanek J, Spitz DR, Domann FE, Scheffler IE, et al. α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II Oncogene. 27: 4324-4335. PMID 18372923 DOI: 10.1038/Onc.2008.69  0.309
2008 Ahmad IM, Abdalla MY, Aykin-Burns N, Simons AL, Oberley LW, Domann FE, Spitz DR. 2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress. Free Radical Biology & Medicine. 44: 826-34. PMID 18155176 DOI: 10.1016/J.Freeradbiomed.2007.11.007  0.413
2008 Domann FE, Niu G. Detection of Pulmonary Gene Transfer Using Iodide-124/Positron Emission Tomography Cancer Imaginglung and Breast Carcinomas. 281-293. DOI: 10.1016/B978-012374212-4.50032-8  0.54
2007 Provenzano MJ, Fitzgerald MP, Krager K, Domann FE. Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 137: 722-8. PMID 17967635 DOI: 10.1016/J.Otohns.2007.07.030  0.666
2007 Hitchler MJ, Domann FE. An epigenetic perspective on the free radical theory of development. Free Radical Biology & Medicine. 43: 1023-36. PMID 17761298 DOI: 10.1016/J.Freeradbiomed.2007.06.027  0.771
2007 Provenzano MJ, Domann FE. A role for epigenetics in hearing: Establishment and maintenance of auditory specific gene expression patterns. Hearing Research. 233: 1-13. PMID 17723285 DOI: 10.1016/J.Heares.2007.07.002  0.372
2007 Provenzano MJ, Yu L, Hitchler MJ, Fitzgerald MP, Robinson RA, Wayne S, Ver Meer M, Domann FE. AP-2 participates in the transcriptional control of the amyloid precursor protein (APP) gene in oral squamous cell carcinoma. Experimental and Molecular Pathology. 83: 277-82. PMID 17651731 DOI: 10.1016/J.Yexmp.2007.06.001  0.769
2007 Ianzini F, Domann FE, Kosmacek EA, Phillips SL, Mackey MA. Human glioblastoma U87MG cells transduced with a dominant negative p53 (TP53) adenovirus construct undergo radiation-induced mitotic catastrophe. Radiation Research. 168: 183-92. PMID 17638400 DOI: 10.1667/0033-7587(2007)168[183:Hguctw]2.0.Co;2  0.304
2007 Menon SG, Sarsour EH, Kalen AL, Venkataraman S, Hitchler MJ, Domann FE, Oberley LW, Goswami PC. Superoxide signaling mediates N-acetyl-L-cysteine-induced G1 arrest: regulatory role of cyclin D1 and manganese superoxide dismutase. Cancer Research. 67: 6392-9. PMID 17616699 DOI: 10.1158/0008-5472.Can-07-0225  0.745
2007 Bock JM, Menon SG, Sinclair LL, Bedford NS, Goswami PC, Domann FE, Trask DK. Celecoxib toxicity is cell cycle phase specific. Cancer Research. 67: 3801-8. PMID 17440094 DOI: 10.1158/0008-5472.Can-06-3780  0.344
2007 Bock JM, Menon SG, Goswami PC, Sinclair LL, Bedford NS, Domann FE, Trask DK. Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition. Molecular Carcinogenesis. 46: 857-64. PMID 17415779 DOI: 10.1002/Mc.20318  0.308
2007 Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE. A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. The Journal of Biological Chemistry. 282: 1322-33. PMID 17110379 DOI: 10.1074/Jbc.M609612200  0.361
2006 Hitchler MJ, Wikainapakul K, Yu L, Powers K, Attatippaholkun W, Domann FE. Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells. Epigenetics. 1: 163-71. PMID 17965603 DOI: 10.4161/Epi.1.4.3401  0.785
2006 Zhao R, Domann FE, Zhong W. Apoptosis induced by selenomethionine and methioninase is superoxide mediated and p53 dependent in human prostate cancer cells. Molecular Cancer Therapeutics. 5: 3275-84. PMID 17172431 DOI: 10.1158/1535-7163.Mct-06-0400  0.363
2006 Lal G, Padmanabha L, Smith BJ, Nicholson RM, Howe JR, O'Dorisio MS, Domann FE. RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma. Cancer. 107: 2752-9. PMID 17103461 DOI: 10.1002/Cncr.22325  0.368
2006 Yu L, Venkataraman S, Coleman MC, Spitz DR, Wertz PW, Domann FE. Glutathione peroxidase-1 inhibits UVA-induced AP-2alpha expression in human keratinocytes. Biochemical and Biophysical Research Communications. 351: 1066-71. PMID 17097614 DOI: 10.1016/J.Bbrc.2006.10.171  0.331
2006 Yu L, Domann FE. Rapid and direct quantitative RT-PCR method to measure promoter activity. Biotechnology Progress. 22: 1461-3. PMID 17022688 DOI: 10.1021/Bp060102E  0.311
2006 Luo J, Li L, Zhang Y, Spitz DR, Buettner GR, Oberley LW, Domann FE. Inactivation of primary antioxidant enzymes in mouse keratinocytes by photodynamically generated singlet oxygen. Antioxidants & Redox Signaling. 8: 1307-14. PMID 16910778 DOI: 10.1089/Ars.2006.8.1307  0.322
2006 Slane BG, Aykin-Burns N, Smith BJ, Kalen AL, Goswami PC, Domann FE, Spitz DR. Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability. Cancer Research. 66: 7615-20. PMID 16885361 DOI: 10.1158/0008-5472.Can-06-0833  0.364
2006 Li H, Goswami PC, Domann FE. AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells. Neoplasia (New York, N.Y.). 8: 568-77. PMID 16867219 DOI: 10.1593/Neo.06367  0.525
2006 Darbro BW, Lee KM, Nguyen NK, Domann FE, Klingelhutz AJ. Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells. Oncogene. 25: 7421-33. PMID 16767161 DOI: 10.1038/Sj.Onc.1209729  0.349
2006 Moussavi-Harami F, Mollano A, Martin JA, Ayoob A, Domann FE, Gitelis S, Buckwalter JA. Intrinsic radiation resistance in human chondrosarcoma cells. Biochemical and Biophysical Research Communications. 346: 379-85. PMID 16765318 DOI: 10.1016/J.Bbrc.2006.05.158  0.317
2006 Li H, Watts GS, Oshiro MM, Futscher BW, Domann FE. AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells. Oncogene. 25: 5405-15. PMID 16636674 DOI: 10.1038/Sj.Onc.1209534  0.501
2006 Niu G, Anderson RD, Madsen MT, Graham MM, Oberley LW, Domann FE. Dual-expressing adenoviral vectors encoding the sodium iodide symporter for use in noninvasive radiological imaging of therapeutic gene transfer. Nuclear Medicine and Biology. 33: 391-8. PMID 16631088 DOI: 10.1016/J.Nucmedbio.2006.01.003  0.551
2006 Zhao R, Xiang N, Domann FE, Zhong W. Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells. Cancer Research. 66: 2296-304. PMID 16489034 DOI: 10.1158/0008-5472.Can-05-2216  0.359
2006 Rose SL, Fitzgerald MP, White NO, Hitchler MJ, Futscher BW, De Geest K, Domann FE. Epigenetic regulation of maspin expression in human ovarian carcinoma cells. Gynecologic Oncology. 102: 319-24. PMID 16457875 DOI: 10.1016/J.Ygyno.2005.12.025  0.782
2006 Andringa KK, Coleman MC, Aykin-Burns N, Hitchler MJ, Walsh SA, Domann FE, Spitz DR. Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose. Cancer Research. 66: 1605-10. PMID 16452219 DOI: 10.1158/0008-5472.Can-05-3462  0.752
2006 Chen P, Cai Y, Yang ZG, Zhou R, Zhang GS, Domann F, Fang X. Involvement of PKC, p38 MAPK and AP-2 in IL-1beta-induced expression of cyclooxygenase-2 in human pulmonary epithelial cells. Respirology (Carlton, Vic.). 11: 18-23. PMID 16423197 DOI: 10.1111/J.1440-1843.2006.00779.X  0.303
2005 Oshiro MM, Futscher BW, Lisberg A, Wozniak RJ, Klimecki WT, Domann FE, Cress AE. Epigenetic regulation of the cell type-specific gene 14-3-3sigma. Neoplasia (New York, N.Y.). 7: 799-808. PMID 16229802 DOI: 10.1593/Neo.05274  0.456
2005 Wang M, Kirk JS, Venkataraman S, Domann FE, Zhang HJ, Schafer FQ, Flanagan SW, Weydert CJ, Spitz DR, Buettner GR, Oberley LW. Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Oncogene. 24: 8154-66. PMID 16170370 DOI: 10.1038/Sj.Onc.1208986  0.32
2005 Oshiro MM, Kim CJ, Wozniak RJ, Junk DJ, Muñoz-Rodríguez JL, Burr JA, Fitzgerald M, Pawar SC, Cress AE, Domann FE, Futscher BW. Epigenetic silencing of DSC3 is a common event in human breast cancer. Breast Cancer Research : Bcr. 7: R669-80. PMID 16168112 DOI: 10.1186/Bcr1273  0.401
2005 Devlin AM, Bottiglieri T, Domann FE, Lentz SR. Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia Journal of Biological Chemistry. 280: 25506-25511. PMID 15899898 DOI: 10.1074/Jbc.M504815200  0.312
2005 Niu G, Krager KJ, Graham MM, Hichwa RD, Domann FE. Noninvasive radiological imaging of pulmonary gene transfer and expression using the human sodium iodide symporter. European Journal of Nuclear Medicine and Molecular Imaging. 32: 534-40. PMID 15599523 DOI: 10.1007/S00259-004-1715-6  0.729
2004 Futscher BW, O'Meara MM, Kim CJ, Rennels MA, Lu D, Gruman LM, Seftor RE, Hendrix MJ, Domann FE. Aberrant methylation of the maspin promoter is an early event in human breast cancer. Neoplasia (New York, N.Y.). 6: 380-9. PMID 15256060 DOI: 10.1593/Neo.04115  0.415
2004 Domann FE, Futscher BW. Flipping the epigenetic switch. The American Journal of Pathology. 164: 1883-6. PMID 15161624 DOI: 10.1016/S0002-9440(10)63748-0  0.46
2004 Watts GS, Oshiro MM, Junk DJ, Wozniak RJ, Watterson S, Domann FE, Futscher BW. The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells. Neoplasia (New York, N.Y.). 6: 187-94. PMID 15153330 DOI: 10.1593/Neo.3292  0.334
2004 Niu G, Gaut AW, Ponto LL, Hichwa RD, Madsen MT, Graham MM, Domann FE. Multimodality noninvasive imaging of gene transfer using the human sodium iodide symporter. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 45: 445-9. PMID 15001685  0.447
2004 Gaut AW, Niu G, Krager KJ, Graham MM, Trask DK, Domann FE. Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS). Head & Neck. 26: 265-71. PMID 14999802 DOI: 10.1002/Hed.10369  0.733
2004 Gaut AW, Krager K, Domann FE. Genetically Targeted Radiotherapy of Head and Neck Squamous Cell Carcinoma Otolaryngology–Head and Neck Surgery. 131: P115-P115. DOI: 10.1016/J.Otohns.2004.06.165  0.692
2003 Fitzgerald M, Oshiro M, Holtan N, Krager K, Cullen JJ, Futscher BW, Domann FE. Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control. Neoplasia (New York, N.Y.). 5: 427-36. PMID 14670180 DOI: 10.1016/S1476-5586(03)80045-3  0.743
2003 Duan H, Zhang HJ, Yang JQ, Oberley LW, Futscher BW, Domann FE. MnSOD up-regulates maspin tumor suppressor gene expression in human breast and prostate cancer cells. Antioxidants & Redox Signaling. 5: 677-88. PMID 14580325 DOI: 10.1089/152308603770310356  0.633
2003 Nwankwo JO, Spector AA, Domann FE. A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency. Journal of Lipid Research. 44: 2311-9. PMID 12951357 DOI: 10.1194/Jlr.M300273-Jlr200  0.391
2003 Zhao L, Wang HP, Zhang HJ, Weydert CJ, Domann FE, Oberley LW, Buettner GR. L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides. Archives of Biochemistry and Biophysics. 417: 212-8. PMID 12941303 DOI: 10.1016/S0003-9861(03)00342-4  0.342
2003 Oshiro MM, Watts GS, Wozniak RJ, Junk DJ, Munoz-Rodriguez JL, Domann FE, Futscher BW. Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. Oncogene. 22: 3624-34. PMID 12789271 DOI: 10.1038/Sj.Onc.1206545  0.416
2003 He T, Weintraub NL, Goswami PC, Chatterjee P, Flaherty DM, Domann FE, Oberley LW. Redox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 285: H804-12. PMID 12730053 DOI: 10.1152/Ajpheart.01080.2002  0.375
2003 Cullen JJ, Weydert C, Hinkhouse MM, Ritchie J, Domann FE, Spitz D, Oberley LW. The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma. Cancer Research. 63: 1297-303. PMID 12649190  0.304
2003 Cullen J, Hinkhouse M, Gaut A, Liu J, Weydert C, Domann F, Oberley L. The role of NAD(P)H:quinone oxidoreductase (NQO1) in redox regulation of pancreatic cancer cell growth Gastroenterology. 124: A291. DOI: 10.1016/S0016-5085(03)81462-2  0.389
2002 Girnun GD, Domann FE, Moore SA, Robbins ME. Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Molecular Endocrinology (Baltimore, Md.). 16: 2793-801. PMID 12456800 DOI: 10.1210/Me.2002-0020  0.383
2002 Futscher BW, Oshiro MM, Wozniak RJ, Holtan N, Hanigan CL, Duan H, Domann FE. Role for DNA methylation in the control of cell type specific maspin expression. Nature Genetics. 31: 175-9. PMID 12021783 DOI: 10.1038/Ng886  0.622
2002 Timmons SR, Nwankwo JO, Domann FE. Acetaldehyde activates Jun/AP-1 expression and DNA binding activity in human oral keratinocytes. Oral Oncology. 38: 281-90. PMID 11978551 DOI: 10.1016/S1368-8375(01)00056-2  0.794
2002 Yang JQ, Buettner GR, Domann FE, Li Q, Engelhardt JF, Weydert CD, Oberley LW. v-Ha-ras mitogenic signaling through superoxide and derived reactive oxygen species. Molecular Carcinogenesis. 33: 206-18. PMID 11933074 DOI: 10.1002/Mc.10037  0.309
2002 Zhu CH, Domann FE. Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth. Breast Cancer Research and Treatment. 71: 47-57. PMID 11859873 DOI: 10.1023/A:1013378113916  0.701
2002 Zhang HJ, Drake VJ, Xu L, Hu J, Domann FE, Oberley LW, Kregel KC. Redox regulation of adenovirus-induced AP-1 activation by overexpression of manganese-containing superoxide dismutase. Journal of Virology. 76: 355-63. PMID 11739700 DOI: 10.1128/Jvi.76.1.355-363.2002  0.373
2001 Yang JQ, Li S, Huang Y, Zhang HJ, Domann FE, Buettner GR, Oberley LW. V-Ha-Ras overexpression induces superoxide production and alters levels of primary antioxidant enzymes. Antioxidants & Redox Signaling. 3: 697-709. PMID 11554455 DOI: 10.1089/15230860152543032  0.358
2001 Yang JQ, Zhao W, Duan H, Robbins ME, Buettner GR, Oberley LW, Domann FE. v-Ha-RaS oncogene upregulates the 92-kDa type IV collagenase (MMP-9) gene by increasing cellular superoxide production and activating NF-kappaB. Free Radical Biology & Medicine. 31: 520-9. PMID 11498285 DOI: 10.1016/S0891-5849(01)00613-X  0.542
2001 Zhu C, Huang Y, Weydert CJ, Oberley LW, Domann FE. Constitutive activation of transcription factor AP-2 is associated with decreased MnSOD expression in transformed human lung fibroblasts. Antioxidants & Redox Signaling. 3: 387-95. PMID 11491651 DOI: 10.1089/15230860152409031  0.728
2001 Zhu CH, Huang Y, Broman MT, Domann FE. Expression of AP-2 alpha in SV40 immortalized human lung fibroblasts is associated with a distinct pattern of cytosine methylation in the AP-2 alpha promoter. Biochimica Et Biophysica Acta. 1519: 85-91. PMID 11406275 DOI: 10.1016/S0167-4781(01)00227-5  0.695
2001 Wang HP, Qian SY, Schafer FQ, Domann FE, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy. Free Radical Biology & Medicine. 30: 825-35. PMID 11295525 DOI: 10.1016/S0891-5849(01)00469-5  0.373
2001 Zhu CH, Huang Y, Oberley LW, Domann FE. A Family of AP-2 Proteins Down-regulate Manganese Superoxide Dismutase Expression Journal of Biological Chemistry. 276: 14407-14413. PMID 11278550 DOI: 10.1074/Jbc.M009708200  0.71
2000 Sekhar KR, Soltaninassab SR, Borrelli MJ, Xu ZQ, Meredith MJ, Domann FE, Freeman ML. Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for gamma-glutamylcysteine synthetase. Biochemical and Biophysical Research Communications. 270: 311-7. PMID 10733945 DOI: 10.1006/Bbrc.2000.2419  0.382
2000 Domann FE, Rice JC, Hendrix MJC, Futscher BW. Epigenetic silencing of maspin gene expression in human breast cancers International Journal of Cancer. 85: 805-810. PMID 10709100 DOI: 10.1002/(Sici)1097-0215(20000315)85:6<805::Aid-Ijc12>3.0.Co;2-5  0.474
2000 Cody DT, Huang Y, Darby CJ, Johnson GK, Domann FE. Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes. Oral Oncology. 35: 516-22. PMID 10694953 DOI: 10.1016/S1368-8375(99)00026-3  0.423
1999 Yang JQ, Li S, Domann FE, Buettner GR, Oberley LW. Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells. Molecular Carcinogenesis. 26: 180-8. PMID 10559793 DOI: 10.1002/(Sici)1098-2744(199911)26:3<180::Aid-Mc7>3.0.Co;2-4  0.302
1999 Huang Y, He T, Domann FE. Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene. Dna and Cell Biology. 18: 643-652. PMID 10463060 DOI: 10.1089/104454999315051  0.423
1999 Huang Y, Domann FE. Transcription factor AP-2 mRNA and DNA binding activity are constitutively expressed in SV40-immortalized but not normal human lung fibroblasts. Archives of Biochemistry and Biophysics. 364: 241-6. PMID 10190980 DOI: 10.1006/Abbi.1999.1142  0.365
1998 Huang Y, Domann FE. Redox modulation of AP-2 DNA binding activity in vitro. Biochemical and Biophysical Research Communications. 249: 307-12. PMID 9712692 DOI: 10.1006/Bbrc.1998.9139  0.332
1997 Kelley EE, Domann FE, Buettner GR, Oberley LW, Burns CP. Increased efficacy of in vitro Photofrin photosensitization of human oral squamous cell carcinoma by iron and ascorbate. Journal of Photochemistry and Photobiology. B, Biology. 40: 273-7. PMID 9372616 DOI: 10.1016/S1011-1344(97)00068-7  0.31
1997 Huang Y, Peng J, Oberley LW, Domann FE. Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5' CpG island Free Radical Biology and Medicine. 23: 314-320. PMID 9199894 DOI: 10.1016/S0891-5849(97)00095-6  0.454
1997 Peng J, Bowden GT, Domann FE. Activation of AP-1 by okadaic acid in mouse keratinocytes associated with hyperphosphorylation of c-jun Molecular Carcinogenesis. 18: 37-43. PMID 9022811 DOI: 10.1002/(Sici)1098-2744(199701)18:1<37::Aid-Mc5>3.0.Co;2-O  0.327
1995 Li JJ, Domann F, Oberley LW. The Use of RT-PCR to Distinguish between Plasmid MnSOD Transcripts and Endogenous MnSOD mRNA Biochemical and Biophysical Research Communications. 216: 610-618. PMID 7488155 DOI: 10.1006/Bbrc.1995.2666  0.339
1994 Domann FE, Levy JP, Finch JS, Bowden GTm. Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells. Molecular Carcinogenesis. 9: 61-66. PMID 8142009 DOI: 10.1002/Mc.2940090202  0.399
1994 Domann FE, Freitas MA, Gould MN, Clifton KH. Quantifying the Frequency of Radiogenic Thyroid Cancer per Clonogenic Cell In Vivo Radiation Research. 137: 330. DOI: 10.2307/3578707  0.329
1991 Clifton KH, Domann FE, Groch KM. On the cells of origin of radiogenic thyroid cancer: new studies based on an old idea. Journal of Radiation Research. 32: 143-55. PMID 1840428 DOI: 10.1269/Jrr.32.Supplement2_143  0.317
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