| Year |
Citation |
Score |
| 2023 |
Kim EE, Shekhar A, Ramachandran J, Khodadadi-Jamayran A, Liu FY, Zhang J, Fishman GI. The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation. Development (Cambridge, England). 150. PMID 37787076 DOI: 10.1242/dev.202054 |
0.407 |
|
| 2022 |
Barefield DY, Yamakawa S, Tahtah I, Sell JJ, Broman M, Laforest B, Harris S, Alvarez-Arce A, Araujo KN, Puckelwartz MJ, Wasserstrom JA, Fishman GI, McNally EM. Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects. Journal of Molecular and Cellular Cardiology. 169: 28-40. PMID 35533732 DOI: 10.1016/j.yjmcc.2022.04.012 |
0.378 |
|
| 2022 |
Blackwell DJ, Faggioni M, Wleklinski MJ, Gomez-Hurtado N, Venkataraman R, Gibbs CE, Baudenbacher FJ, Gong S, Fishman GI, Boyle PM, Pfeifer K, Knollmann BC. The Purkinje-myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT. Jci Insight. 7. PMID 34990403 DOI: 10.1172/jci.insight.151893 |
0.386 |
|
| 2021 |
Delgado C, Bu L, Zhang J, Liu FY, Sall J, Liang FX, Furley AJ, Fishman GI. Neural cell adhesion molecule is required for ventricular conduction system development. Development (Cambridge, England). 148. PMID 34100064 DOI: 10.1242/dev.199431 |
0.391 |
|
| 2021 |
Delgado C, Bu L, Zhang J, Fang-Yu L, Sall J, Liang FX, Furley AJ, Fishman GI. Neural cell adhesion molecule (NCAM-1) is required for ventricular conduction system development. Development (Cambridge, England). PMID 33948634 DOI: 10.1242/dev.199431 |
0.393 |
|
| 2020 |
Park DS, Shekhar A, Santucci Iii J, Redel-Traub G, Solinas SM, Mintz S, Lin X, Chang EW, Narke D, Xia Y, Goldfarb M, Fishman GI. Ionic Mechanisms of Impulse Propagation Failure in the FHF2-Deficient Heart. Circulation Research. PMID 32962518 DOI: 10.1161/CIRCRESAHA.120.317349 |
0.345 |
|
| 2020 |
Shekhar A, Aristizabal O, Fishman GI, Phoon CKL, Ketterling JA. Characterization of vortex flow in a mouse model of ventricular dyssynchrony by plane-wave ultrasound using hexplex processing. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. PMID 32763851 DOI: 10.1109/Tuffc.2020.3014844 |
0.383 |
|
| 2020 |
Fishman GI. TRANSCRIPTIONAL REGULATION OF THE CARDIAC CONDUCTION SYSTEM. Transactions of the American Clinical and Climatological Association. 131: 48-54. PMID 32675842 |
0.412 |
|
| 2020 |
Himelman E, Lillo MA, Nouet J, Gonzalez JP, Zhao Q, Xie LH, Li H, Liu T, Wehrens XH, Lampe PD, Fishman GI, Shirokova N, Contreras JE, Fraidenraich D. Prevention of Connexin43 remodeling protects against duchenne muscular dystrophy cardiomyopathy. The Journal of Clinical Investigation. PMID 31910160 DOI: 10.1172/Jci128190 |
0.459 |
|
| 2019 |
Gando I, Williams N, Fishman GI, Sampson BA, Tang Y, Coetzee WA. Functional characterization of SCN10A variants in several cases of sudden unexplained death. Forensic Science International. 301: 289-298. PMID 31195250 DOI: 10.1016/J.Forsciint.2019.05.042 |
0.314 |
|
| 2019 |
Cappola AR, Desai AS, Medici M, Cooper LS, Egan D, Sopko G, Fishman GI, Goldman S, Cooper DS, Mora S, Kudenchuk PJ, Hollenberg AN, McDonald CL, Ladenson PW. Thyroid and Cardiovascular Disease: Research Agenda for Enhancing Knowledge, Prevention, and Treatment. Thyroid : Official Journal of the American Thyroid Association. PMID 31081722 DOI: 10.1089/Thy.2018.0416 |
0.312 |
|
| 2019 |
Cappola AR, Desai AS, Medici M, Cooper LS, Egan D, Sopko G, Fishman GI, Goldman S, Cooper DS, Mora S, Kudenchuk PJ, Hollenberg AN, McDonald CL, Ladenson PW. Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment. Circulation. PMID 31081673 DOI: 10.1161/Circulationaha.118.036859 |
0.312 |
|
| 2019 |
Barefield DY, Yamakawa S, Tahtah I, Sell JJ, Broman M, Laforest B, Pickelwartz MJ, Wilsbacher LD, Wasserstrom A, Fishman GI, McNally E. Abstract 331: Loss of Myosin Binding Protein H-Like Causes Cardiac Conduction Abnormalities Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.331 |
0.353 |
|
| 2019 |
Redel-Traub G, Shekhar A, Santucci J, Mintz S, Liu F, Zhang J, Park D, Goldfarb M, Fishman G. FHF2 SAFEGUARDS THE HEART AGAINST REDUCTIONS IN JUNCTIONAL CONDUCTANCE Journal of the American College of Cardiology. 73: 350. DOI: 10.1016/S0735-1097(19)30958-1 |
0.417 |
|
| 2018 |
Shekhar A, Lin X, Lin B, Liu FY, Zhang J, Khodadadi-Jamayran A, Tsirigos A, Bu L, Fishman GI, Park DS. ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes. Scientific Reports. 8: 9944. PMID 29967479 DOI: 10.1038/S41598-018-28239-7 |
0.501 |
|
| 2018 |
Park DS, Fishman GI. SCN5A: the greatest HITS collection. The Journal of Clinical Investigation. PMID 29457788 DOI: 10.1172/Jci99927 |
0.37 |
|
| 2018 |
Barefield DY, Sell JJ, Puckelwartz MJ, Wilsbacher LD, Fishman GI, McNally EM. Abstract 116:
Mybphl
is a Novel Myofilament Component Implicated in Arrhythmia and Dilated Cardiomyopathy Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.116 |
0.331 |
|
| 2017 |
Park DS, Fishman GI. Development and Function of the Cardiac Conduction System in Health and Disease. Journal of Cardiovascular Development and Disease. 4. PMID 29098150 DOI: 10.3390/Jcdd4020007 |
0.494 |
|
| 2016 |
Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS. Transcription factor ETV1 is essential for rapid conduction in the heart. The Journal of Clinical Investigation. PMID 27775552 DOI: 10.1172/Jci87968 |
0.526 |
|
| 2016 |
Park DS, Shekhar A, Marra C, Lin X, Vasquez C, Solinas S, Kelley K, Morley G, Goldfarb M, Fishman GI. Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure. Nature Communications. 7: 12966. PMID 27701382 DOI: 10.1038/Ncomms12966 |
0.428 |
|
| 2015 |
Iyer V, Roman-Campos D, Sampson KJ, Kang G, Fishman GI, Kass RS. Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3. Scientific Reports. 5: 13287. PMID 26289036 DOI: 10.1038/Srep13287 |
0.434 |
|
| 2015 |
Tsai SY, Maass K, Lu J, Fishman GI, Chen S, Evans T. Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling. Stem Cell Reports. 4: 1089-102. PMID 26028533 DOI: 10.1016/J.Stemcr.2015.04.015 |
0.465 |
|
| 2015 |
Lin X, O'Malley H, Chen C, Auerbach D, Foster M, Shekhar A, Zhang M, Coetzee W, Jalife J, Fishman GI, Isom L, Delmar M. Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts. The Journal of Physiology. 593: 1389-407. PMID 25772295 DOI: 10.1113/Jphysiol.2014.277699 |
0.375 |
|
| 2015 |
Maass K, Shekhar A, Lu J, Kang G, See F, Kim EE, Delgado C, Shen S, Cohen L, Fishman GI. Isolation and characterization of embryonic stem cell-derived cardiac Purkinje cells. Stem Cells (Dayton, Ohio). 33: 1102-12. PMID 25524238 DOI: 10.1002/Stem.1921 |
0.396 |
|
| 2015 |
Park DS, Cerrone M, Morley G, Vasquez C, Fowler S, Liu N, Bernstein SA, Liu FY, Zhang J, Rogers CS, Priori SG, Chinitz LA, Fishman GI. Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias. The Journal of Clinical Investigation. 125: 403-12. PMID 25500882 DOI: 10.1172/Jci76919 |
0.482 |
|
| 2014 |
Kim EE, Shekhar A, Lu J, Lin X, Liu FY, Zhang J, Delmar M, Fishman GI. PCP4 regulates Purkinje cell excitability and cardiac rhythmicity. The Journal of Clinical Investigation. 124: 5027-36. PMID 25295538 DOI: 10.1172/Jci77495 |
0.471 |
|
| 2014 |
Lin X, O'Malley H, Chen C, Auerbach D, Foster M, Shekhar A, Zhang M, Coetzee W, Jalife J, Fishman GI, Isom L, Delmar M. Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts. The Journal of Physiology. PMID 25128572 DOI: 10.1113/jphysiol.2014.277699 |
0.31 |
|
| 2014 |
Josowitz R, Lu J, Falce C, D'Souza SL, Wu M, Cohen N, Dubois NC, Zhao Y, Sobie EA, Fishman GI, Gelb BD. Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression. Plos One. 9: e101316. PMID 25010565 DOI: 10.1371/Journal.Pone.0101316 |
0.393 |
|
| 2014 |
Hartman ME, Liu Y, Zhu WZ, Chien WM, Weldy CS, Fishman GI, Laflamme MA, Chin MT. Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3007-15. PMID 24687990 DOI: 10.1096/Fj.14-251728 |
0.517 |
|
| 2014 |
Park DS, Fishman GI. Nav-igating through a complex landscape: SCN10A and cardiac conduction. The Journal of Clinical Investigation. 124: 1460-2. PMID 24642462 DOI: 10.1172/Jci75240 |
0.5 |
|
| 2014 |
Huang T, Shao Q, Barr K, Simek J, Fishman GI, Laird DW. Myogenic bladder defects in mouse models of human oculodentodigital dysplasia. The Biochemical Journal. 457: 441-9. PMID 24228978 DOI: 10.1042/Bj20130810 |
0.354 |
|
| 2013 |
Park DS, Tompkins RO, Liu F, Zhang J, Phoon CK, Zavadil J, Fishman GI. Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system. Biology Open. 2: 968-78. PMID 24143284 DOI: 10.1242/Bio.20135785 |
0.466 |
|
| 2013 |
Turbendian HK, Gordillo M, Tsai SY, Lu J, Kang G, Liu TC, Tang A, Liu S, Fishman GI, Evans T. GATA factors efficiently direct cardiac fate from embryonic stem cells. Development (Cambridge, England). 140: 1639-44. PMID 23487308 DOI: 10.1242/Dev.093260 |
0.422 |
|
| 2013 |
Danielson LS, Park DS, Rotllan N, Chamorro-Jorganes A, Guijarro MV, Fernandez-Hernando C, Fishman GI, Phoon CK, Hernando E. Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1460-7. PMID 23271053 DOI: 10.1096/Fj.12-221994 |
0.32 |
|
| 2013 |
Kim E, Fishman GI. Designer gap junctions that prevent cardiac arrhythmias. Trends in Cardiovascular Medicine. 23: 33-8. PMID 23245912 DOI: 10.1016/J.Tcm.2012.08.008 |
0.452 |
|
| 2013 |
Stewart MK, Gong XQ, Barr KJ, Bai D, Fishman GI, Laird DW. The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice. The Biochemical Journal. 449: 401-13. PMID 23075222 DOI: 10.1042/Bj20121070 |
0.388 |
|
| 2013 |
Maass K, Lu J, See F, D'Souza S, Fishman GI. Development of a Mouse ESC Reporter Line to Isolate Purkinje-Like Cardiac Conduction System Cells Heart Rhythm. 10: 1748. DOI: 10.1016/J.Hrthm.2013.09.036 |
0.391 |
|
| 2013 |
Kim EE, Shekhar A, Zhang J, Liu F, Fishman GI. PCP4 Is a Key Regulator of Cardiac Purkinje Cell Calcium Homeostasis and Suppresses Arrhythmogenic Calcium Waves Heart Rhythm. 10: 1746. DOI: 10.1016/J.Hrthm.2013.09.029 |
0.413 |
|
| 2012 |
Rentschler S, Yen AH, Lu J, Petrenko NB, Lu MM, Manderfield LJ, Patel VV, Fishman GI, Epstein JA. Myocardial Notch signaling reprograms cardiomyocytes to a conduction-like phenotype. Circulation. 126: 1058-66. PMID 22837163 DOI: 10.1161/Circulationaha.112.103390 |
0.689 |
|
| 2012 |
Lorentz R, Shao Q, Huang T, Fishman GI, Laird DW. Characterization of gap junction proteins in the bladder of Cx43 mutant mouse models of oculodentodigital dysplasia. The Journal of Membrane Biology. 245: 345-55. PMID 22752022 DOI: 10.1007/S00232-012-9455-1 |
0.348 |
|
| 2012 |
Remo BF, Giovannone S, Fishman GI. Connexin43 cardiac gap junction remodeling: lessons from genetically engineered murine models. The Journal of Membrane Biology. 245: 275-81. PMID 22722763 DOI: 10.1007/S00232-012-9448-0 |
0.455 |
|
| 2012 |
Park DS, Fishman GI. Forever young: induced pluripotent stem cells as models of inherited arrhythmias. Circulation. 125: 3055-6. PMID 22647977 DOI: 10.1161/Circulationaha.112.114165 |
0.353 |
|
| 2012 |
Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA. Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 9071-6. PMID 22611193 DOI: 10.1073/Pnas.1120358109 |
0.328 |
|
| 2012 |
Gonzalez-Nieto D, Li L, Kohler A, Ghiaur G, Ishikawa E, Sengupta A, Madhu M, Arnett JL, Santho RA, Dunn SK, Fishman GI, Gutstein DE, Civitelli R, Barrio LC, Gunzer M, et al. Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood. 119: 5144-54. PMID 22498741 DOI: 10.1182/Blood-2011-07-368506 |
0.331 |
|
| 2012 |
Giovannone S, Remo BF, Fishman GI. Channeling diversity: gap junction expression in the heart. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 1159-62. PMID 22120127 DOI: 10.1016/J.Hrthm.2011.11.040 |
0.409 |
|
| 2012 |
Kim E, Fishman GI. Chapter 40 – The Structural Basis of Arrhythmia Musclefundamental Biology and Mechanisms of Disease. 571-582. DOI: 10.1016/B978-0-12-381510-1.00040-5 |
0.427 |
|
| 2011 |
Albert CM, Chen PS, Anderson ME, Cain ME, Fishman GI, Narayan SM, Olgin JE, Spooner PM, Stevenson WG, Van Wagoner DR, Packer DL. Full report from the first annual Heart Rhythm Society Research Forum: a vision for our research future, "dream, discover, develop, deliver". Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: e1-12. PMID 22079558 DOI: 10.1016/J.Hrthm.2011.10.024 |
0.393 |
|
| 2011 |
Bao L, Kefaloyianni E, Lader J, Hong M, Morley G, Fishman GI, Sobie EA, Coetzee WA. Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system. Circulation. Arrhythmia and Electrophysiology. 4: 926-35. PMID 21984445 DOI: 10.1161/Circep.111.964643 |
0.374 |
|
| 2011 |
Lin X, Liu N, Lu J, Zhang J, Anumonwo JM, Isom LL, Fishman GI, Delmar M. Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 1923-30. PMID 21767519 DOI: 10.1016/J.Hrthm.2011.07.016 |
0.331 |
|
| 2011 |
Lader JM, Vasquez C, Bao L, Maass K, Qu J, Kefalogianni E, Fishman GI, Coetzee WA, Morley GE. Remodeling of atrial ATP-sensitive K⁺ channels in a model of salt-induced elevated blood pressure. American Journal of Physiology. Heart and Circulatory Physiology. 301: H964-74. PMID 21724863 DOI: 10.1152/Ajpheart.00410.2011 |
0.411 |
|
| 2011 |
Levin RI, Fishman GI. The power of Pasteur's quadrant: cardiovascular disease at the turn of the century. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1788-92. PMID 21622696 DOI: 10.1096/Fj.11-0604Ufm |
0.337 |
|
| 2011 |
Remo BF, Qu J, Volpicelli FM, Giovannone S, Shin D, Lader J, Liu FY, Zhang J, Lent DS, Morley GE, Fishman GI. Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias. Circulation Research. 108: 1459-66. PMID 21527737 DOI: 10.1161/Circresaha.111.244046 |
0.432 |
|
| 2011 |
Chin KT, Kang G, Qu J, Gardner LB, Coetzee WA, Zito E, Fishman GI, Ron D. The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2583-91. PMID 21507899 DOI: 10.1096/Fj.11-184622 |
0.38 |
|
| 2011 |
Park DS, Fishman GI. The cardiac conduction system. Circulation. 123: 904-15. PMID 21357845 DOI: 10.1161/Circulationaha.110.942284 |
0.468 |
|
| 2011 |
Albert CM, Chen P, Anderson ME, Cain ME, Fishman GI, Narayan SM, Olgin JE, Spooner PM, Stevenson WG, Wagoner DRV, Packer DL. Executive Summary from the First Annual Heart Rhythm Society Research Forum: A Vision for Our Research Future, “Dream, Discover, Develop, Deliver” Heart Rhythm. 8: 1992-1993. DOI: 10.1016/J.Hrthm.2011.11.015 |
0.312 |
|
| 2011 |
Bao L, Kefalogianni E, Hong M, Coetzee A, Morley G, Fishman G, Coetzee W. Properties and Molecular Composition of Mouse and Canine Cardiac Purkinje Fiber ATP-Sensitive K+ Channels Biophysical Journal. 100: 432a. DOI: 10.1016/J.Bpj.2010.12.2552 |
0.393 |
|
| 2011 |
Spray DC, Suadicani SO, Srinivas M, Gutstein DE, Fishman GI. Gap Junctions in the Cardiovascular System Comprehensive Physiology. 169-212. DOI: 10.1002/Cphy.Cp020104 |
0.445 |
|
| 2010 |
Fishman GI, Chugh SS, Dimarco JP, Albert CM, Anderson ME, Bonow RO, Buxton AE, Chen PS, Estes M, Jouven X, Kwong R, Lathrop DA, Mascette AM, Nerbonne JM, O'Rourke B, et al. Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation. 122: 2335-48. PMID 21147730 DOI: 10.1161/Circulationaha.110.976092 |
0.388 |
|
| 2010 |
Sotoodehnia N, Isaacs A, de Bakker PI, Dörr M, Newton-Cheh C, Nolte IM, van der Harst P, Müller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, ... ... Fishman GI, et al. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nature Genetics. 42: 1068-76. PMID 21076409 DOI: 10.1038/Ng.716 |
0.438 |
|
| 2010 |
Kang G, Giovannone SF, Liu N, Liu FY, Zhang J, Priori SG, Fishman GI. Purkinje cells from RyR2 mutant mice are highly arrhythmogenic but responsive to targeted therapy. Circulation Research. 107: 512-9. PMID 20595652 DOI: 10.1161/Circresaha.110.221481 |
0.316 |
|
| 2010 |
Pallante BA, Giovannone S, Fang-Yu L, Zhang J, Liu N, Kang G, Dun W, Boyden PA, Fishman GI. Contactin-2 expression in the cardiac Purkinje fiber network. Circulation. Arrhythmia and Electrophysiology. 3: 186-94. PMID 20110552 DOI: 10.1161/Circep.109.928820 |
0.37 |
|
| 2010 |
Remo BF, Fishman GI. A colorful explanation for atrial arrhythmias. Pigment Cell & Melanoma Research. 23: 3-4. PMID 19968821 DOI: 10.1111/J.1755-148X.2009.00658.X |
0.503 |
|
| 2009 |
Qu J, Volpicelli FM, Garcia LI, Sandeep N, Zhang J, Márquez-Rosado L, Lampe PD, Fishman GI. Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart. Circulation Research. 104: 365-71. PMID 19096029 DOI: 10.1161/Circresaha.108.184044 |
0.47 |
|
| 2009 |
Gonzalez-Nieto D, Chang K, Koehler A, Arnett J, Dunn S, Li L, Ghiaur G, Sengupta A, Fishman G, Gutstein D, Civitelli R, Barrio L, Gunzer M, Cancelas J. Connexin-43 Expression Regulates the Migration of Hematopoietic Stem Cells and Progenitors towards and From Bone Marrow. Blood. 114: 562-562. DOI: 10.1182/Blood.V114.22.562.562 |
0.366 |
|
| 2009 |
Gonzalez-Nieto D, Ghiaur G, Li L, Arnett J, Dunn S, Fishman G, Gutstein D, Civitelli R, Cancelas J. Connexin-43 Regulates the Cell Cycle Entry of Hematopoietic Stem Cells within the Stem Cell Niche. Blood. 114: 1500-1500. DOI: 10.1182/Blood.V114.22.1500.1500 |
0.349 |
|
| 2008 |
Mori Y, Fishman GI, Peskin CS. Ephaptic conduction in a cardiac strand model with 3D electrodiffusion. Proceedings of the National Academy of Sciences of the United States of America. 105: 6463-8. PMID 18434544 DOI: 10.1073/Pnas.0801089105 |
0.408 |
|
| 2008 |
Wolf CM, Wang L, Alcalai R, Pizard A, Burgon PG, Ahmad F, Sherwood M, Branco DM, Wakimoto H, Fishman GI, See V, Stewart CL, Conner DA, Berul CI, Seidman CE, et al. Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease. Journal of Molecular and Cellular Cardiology. 44: 293-303. PMID 18182166 DOI: 10.1016/J.Yjmcc.2007.11.008 |
0.457 |
|
| 2008 |
Danik SB, Rosner G, Lader J, Gutstein DE, Fishman GI, Morley GE. Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1204-12. PMID 17984180 DOI: 10.1096/Fj.07-8974Com |
0.49 |
|
| 2008 |
Stroud DM, Yu C, Fishman GI, Morley GE, Gaussin V, Burch JBE, Mishina Y, Schneider MD. Response to letters regarding article, "abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor" Circulation. 118: e107. DOI: 10.1161/Circulationaha.108.773457 |
0.307 |
|
| 2007 |
Kalcheva N, Qu J, Sandeep N, Garcia L, Zhang J, Wang Z, Lampe PD, Suadicani SO, Spray DC, Fishman GI. Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 20512-6. PMID 18077386 DOI: 10.1073/Pnas.0705472105 |
0.492 |
|
| 2007 |
Stroud DM, Gaussin V, Burch JB, Yu C, Mishina Y, Schneider MD, Fishman GI, Morley GE. Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Circulation. 116: 2535-43. PMID 17998461 DOI: 10.1161/Circulationaha.107.696583 |
0.373 |
|
| 2007 |
Viswanathan S, Burch JB, Fishman GI, Moskowitz IP, Benson DW. Characterization of sinoatrial node in four conduction system marker mice. Journal of Molecular and Cellular Cardiology. 42: 946-53. PMID 17459410 DOI: 10.1016/J.Yjmcc.2007.02.008 |
0.406 |
|
| 2007 |
Stroud DM, Darrow BJ, Kim SD, Zhang J, Jongbloed MR, Rentschler S, Moskowitz IP, Seidman J, Fishman GI. Complex genomic rearrangement in CCS-LacZ transgenic mice. Genesis (New York, N.Y. : 2000). 45: 76-82. PMID 17269130 DOI: 10.1002/Dvg.20267 |
0.708 |
|
| 2007 |
Sridharan S, Simon L, Meling DD, Cyr DG, Gutstein DE, Fishman GI, Guillou F, Cooke PS. Proliferation of adult sertoli cells following conditional knockout of the Gap junctional protein GJA1 (connexin 43) in mice. Biology of Reproduction. 76: 804-12. PMID 17229929 DOI: 10.1095/Biolreprod.106.059212 |
0.381 |
|
| 2007 |
Collis LP, Meyers MB, Zhang J, Phoon CK, Sobie EA, Coetzee WA, Fishman GI. Expression of a sorcin missense mutation in the heart modulates excitation-contraction coupling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 475-87. PMID 17130302 DOI: 10.1096/Fj.06-6292Com |
0.404 |
|
| 2006 |
Yang L, Cai CL, Lin L, Qyang Y, Chung C, Monteiro RM, Mummery CL, Fishman GI, Cogen A, Evans S. Isl1Cre reveals a common Bmp pathway in heart and limb development. Development (Cambridge, England). 133: 1575-85. PMID 16556916 DOI: 10.1242/Dev.02322 |
0.489 |
|
| 2006 |
Tong X, Porter LM, Liu G, Dhar-Chowdhury P, Srivastava S, Pountney DJ, Yoshida H, Artman M, Fishman GI, Yu C, Iyer R, Morley GE, Gutstein DE, Coetzee WA. Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. American Journal of Physiology. Heart and Circulatory Physiology. 291: H543-51. PMID 16501027 DOI: 10.1152/Ajpheart.00051.2006 |
0.432 |
|
| 2005 |
Presley CA, Lee AW, Kastl B, Igbinosa I, Yamada Y, Fishman GI, Gutstein DE, Cancelas JA. Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy. Cell Communication & Adhesion. 12: 307-17. PMID 16531325 DOI: 10.1080/15419060500514200 |
0.384 |
|
| 2005 |
Wolf CM, Moskowitz IP, Arno S, Branco DM, Semsarian C, Bernstein SA, Peterson M, Maida M, Morley GE, Fishman G, Berul CI, Seidman CE, Seidman JG. Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 102: 18123-8. PMID 16332958 DOI: 10.1073/Pnas.0509145102 |
0.457 |
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| 2005 |
Fishman GI. Gap junction remodeling and ventricular arrhythmias. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 2: 887-9. PMID 16051129 DOI: 10.1016/J.Hrthm.2005.05.001 |
0.398 |
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| 2005 |
Gaussin V, Morley GE, Cox L, Zwijsen A, Vance KM, Emile L, Tian Y, Liu J, Hong C, Myers D, Conway SJ, Depre C, Mishina Y, Behringer RR, Hanks MC, ... ... Fishman GI, et al. Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circulation Research. 97: 219-26. PMID 16037571 DOI: 10.1161/01.Res.0000177862.85474.63 |
0.435 |
|
| 2005 |
Ouvrard-Pascaud A, Sainte-Marie Y, Bénitah JP, Perrier R, Soukaseum C, Nguyen Dinh Cat A, Royer A, Le Quang K, Charpentier F, Demolombe S, Mechta-Grigoriou F, Beggah AT, Maison-Blanche P, Oblin ME, Delcayre C, ... Fishman GI, et al. Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. Circulation. 111: 3025-33. PMID 15939817 DOI: 10.1161/Circulationaha.104.503706 |
0.425 |
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| 2005 |
Gutstein DE, Danik SB, Lewitton S, France D, Liu F, Chen FL, Zhang J, Ghodsi N, Morley GE, Fishman GI. Focal gap junction uncoupling and spontaneous ventricular ectopy. American Journal of Physiology. Heart and Circulatory Physiology. 289: H1091-8. PMID 15894579 DOI: 10.1152/Ajpheart.00095.2005 |
0.471 |
|
| 2005 |
Fishman GI. Understanding conduction system development: a hop, skip and jump away? Circulation Research. 96: 809-11. PMID 15860760 DOI: 10.1161/01.Res.0000165653.83279.20 |
0.421 |
|
| 2005 |
Jongbloed MR, Wijffels MC, Schalij MJ, Blom NA, Poelmann RE, van der Laarse A, Mentink MM, Wang Z, Fishman GI, Gittenberger-de Groot AC. Development of the right ventricular inflow tract and moderator band: a possible morphological and functional explanation for Mahaim tachycardia. Circulation Research. 96: 776-83. PMID 15761198 DOI: 10.1161/01.Res.0000162000.03997.65 |
0.412 |
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| 2005 |
Morley GE, Danik SB, Bernstein S, Sun Y, Rosner G, Gutstein DE, Fishman GI. Reduced intercellular coupling leads to paradoxical propagation across the Purkinje-ventricular junction and aberrant myocardial activation. Proceedings of the National Academy of Sciences of the United States of America. 102: 4126-9. PMID 15753312 DOI: 10.1073/Pnas.0500881102 |
0.514 |
|
| 2004 |
Danik SB, Liu F, Zhang J, Suk HJ, Morley GE, Fishman GI, Gutstein DE. Modulation of cardiac gap junction expression and arrhythmic susceptibility. Circulation Research. 95: 1035-41. PMID 15499029 DOI: 10.1161/01.Res.0000148664.33695.2A |
0.496 |
|
| 2004 |
Myers DC, Fishman GI. Toward an understanding of the genetics of murine cardiac pacemaking and conduction system development. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 280: 1018-21. PMID 15368345 DOI: 10.1002/Ar.A.20077 |
0.46 |
|
| 2004 |
Poelmann RE, Jongbloed MR, Molin DG, Fekkes ML, Wang Z, Fishman GI, Doetschman T, Azhar M, Gittenberger-de Groot AC. The neural crest is contiguous with the cardiac conduction system in the mouse embryo: a role in induction? Anatomy and Embryology. 208: 389-93. PMID 15248063 DOI: 10.1007/S00429-004-0401-6 |
0.509 |
|
| 2004 |
Vink MJ, Suadicani SO, Vieira DM, Urban-Maldonado M, Gao Y, Fishman GI, Spray DC. Alterations of intercellular communication in neonatal cardiac myocytes from connexin43 null mice. Cardiovascular Research. 62: 397-406. PMID 15094359 DOI: 10.1016/J.Cardiores.2004.01.015 |
0.459 |
|
| 2004 |
Jongbloed MR, Schalij MJ, Poelmann RE, Blom NA, Fekkes ML, Wang Z, Fishman GI, Gittenberger-De Groot AC. Embryonic conduction tissue: a spatial correlation with adult arrhythmogenic areas. Journal of Cardiovascular Electrophysiology. 15: 349-55. PMID 15030427 DOI: 10.1046/J.1540-8167.2004.03487.X |
0.411 |
|
| 2004 |
Jongbloed MRm, Schalij MJ, Poelmann RE, Fishman GI, Wang Z, Groot ACG. 1001-17 Cardiac conduction system-L acZ expression in the atrioventricular ring and moderator band of transgenic murine embryos: A developmental substrate for Wolff-Parkinson-White syndrome and mahaim tachycardia? Journal of the American College of Cardiology. 43. DOI: 10.1016/S0735-1097(04)90016-2 |
0.387 |
|
| 2003 |
Myers DC, Fishman GI. Molecular and functional maturation of the murine cardiac conduction system. Trends in Cardiovascular Medicine. 13: 289-95. PMID 14522469 DOI: 10.1101/Sqb.2002.67.353 |
0.436 |
|
| 2003 |
Yao JA, Gutstein DE, Liu F, Fishman GI, Wit AL. Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts. Circulation Research. 93: 736-43. PMID 14500334 DOI: 10.1161/01.Res.0000095977.66660.86 |
0.467 |
|
| 2003 |
Rentschler S, Morley GE, Fishman GI. Patterning of the mouse conduction system. Novartis Foundation Symposium. 250: 194-205; discussion . PMID 12956331 DOI: 10.1002/0470868066.Ch12 |
0.746 |
|
| 2003 |
Meyers MB, Fischer A, Sun YJ, Lopes CM, Rohacs T, Nakamura TY, Zhou YY, Lee PC, Altschuld RA, McCune SA, Coetzee WA, Fishman GI. Sorcin regulates excitation-contraction coupling in the heart. The Journal of Biological Chemistry. 278: 28865-71. PMID 12754254 DOI: 10.1074/Jbc.M302009200 |
0.431 |
|
| 2003 |
Gutstein DE, Danik SB, Sereysky JB, Morley GE, Fishman GI. Subdiaphragmatic murine electrophysiological studies: sequential determination of ventricular refractoriness and arrhythmia induction. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1091-6. PMID 12750061 DOI: 10.1152/Ajpheart.00100.2003 |
0.357 |
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| 2003 |
Czubryt MP, McAnally J, Fishman GI, Olson EN. Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5. Proceedings of the National Academy of Sciences of the United States of America. 100: 1711-6. PMID 12578979 DOI: 10.1073/Pnas.0337639100 |
0.38 |
|
| 2003 |
Gutstein DE, Liu FY, Meyers MB, Choo A, Fishman GI. The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions. Journal of Cell Science. 116: 875-85. PMID 12571285 DOI: 10.1242/Jcs.00258 |
0.486 |
|
| 2002 |
Pennisi DJ, Rentschler S, Gourdie RG, Fishman GI, Mikawa T. Induction and patterning of the cardiac conduction system. The International Journal of Developmental Biology. 46: 765-75. PMID 12382942 DOI: 10.1387/Ijdb.12382942 |
0.736 |
|
| 2002 |
Rentschler S, Zander J, Meyers K, France D, Levine R, Porter G, Rivkees SA, Morley GE, Fishman GI. Neuregulin-1 promotes formation of the murine cardiac conduction system. Proceedings of the National Academy of Sciences of the United States of America. 99: 10464-9. PMID 12149465 DOI: 10.1073/Pnas.162301699 |
0.758 |
|
| 2002 |
Degenhardt K, Rentschler S, Fishman G, Sassoon DA. Cellular and cis-regulation of En-2 expression in the mandibular arch. Mechanisms of Development. 111: 125-36. PMID 11804784 DOI: 10.1016/S0925-4773(01)00618-9 |
0.676 |
|
| 2001 |
Gutstein DE, Morley GE, Fishman GI. Conditional gene targeting of connexin43: exploring the consequences of gap junction remodeling in the heart. Cell Communication and Adhesion. 8: 345-348. PMID 12064616 DOI: 10.3109/15419060109080751 |
0.529 |
|
| 2001 |
Gutstein DE, Morley GE, Vaidya D, Liu F, Chen FL, Stuhlmann H, Fishman GI. Heterogeneous Expression of Gap Junction Channels in the Heart Leads to Conduction Defects and Ventricular Dysfunction Circulation. 104: 1194-1199. PMID 11535579 DOI: 10.1161/Hc3601.093990 |
0.507 |
|
| 2001 |
Gutstein DE, Morley GE, Tamaddon H, Vaidya D, Schneider MD, Chen J, Chien KR, Stuhlmann H, Fishman GI. Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circulation Research. 88: 333-9. PMID 11179202 DOI: 10.1161/01.Res.88.3.333 |
0.516 |
|
| 2000 |
Cui J, Melman Y, Palma E, Fishman GI, McDonald TV. Cyclic AMP regulates the HERG K(+) channel by dual pathways. Current Biology. 10: 671-674. PMID 10837251 DOI: 10.1016/S0960-9822(00)00516-9 |
0.341 |
|
| 2000 |
Redfern CH, Degtyarev MY, Kwa AT, Salomonis N, Cotte N, Nanevicz T, Fidelman N, Desai K, Vranizan K, Lee EK, Coward P, Shah N, Warrington JA, Fishman GI, Bernstein D, et al. Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 97: 4826-31. PMID 10781088 DOI: 10.1073/Pnas.97.9.4826 |
0.432 |
|
| 2000 |
Kagan A, Yu Z, Fishman GI, McDonald TV. The Dominant Negative LQT2 Mutation A561V Reduces Wild-type HERG Expression Journal of Biological Chemistry. 275: 11241-11248. PMID 10753933 DOI: 10.1074/Jbc.275.15.11241 |
0.318 |
|
| 2000 |
Ai Z, Fischer A, Spray DC, Brown AM, Fishman GI. Wnt-1 regulation of connexin43 in cardiac myocytes. The Journal of Clinical Investigation. 105: 161-71. PMID 10642594 DOI: 10.1172/Jci7798 |
0.453 |
|
| 1999 |
Wickenden AD, Lee P, Sah R, Huang Q, Fishman GI, Backx PH. Targeted expression of a dominant-negative K(v)4.2 K(+) channel subunit in the mouse heart. Circulation Research. 85: 1067-76. PMID 10571538 DOI: 10.1161/01.Res.85.11.1067 |
0.442 |
|
| 1999 |
Redfern CH, Coward P, Degtyarev MY, Lee EK, Kwa AT, Hennighausen L, Bujard H, Fishman GI, Conklin BR. Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice. Nature Biotechnology. 17: 165-9. PMID 10052353 DOI: 10.1038/6165 |
0.382 |
|
| 1998 |
Lee P, Morley G, Huang Q, Fischer A, Seiler S, Horner JW, Factor S, Vaidya D, Jalife J, Fishman GI. Conditional lineage ablation to model human diseases Proceedings of the National Academy of Sciences of the United States of America. 95: 11371-11376. PMID 9736743 DOI: 10.1073/Pnas.95.19.11371 |
0.512 |
|
| 1998 |
Meyers MB, Puri TS, Chien AJ, Gao T, Hsu PH, Hosey MM, Fishman GI. Sorcin associates with the pore-forming subunit of voltage-dependent L- type Ca2+ channels Journal of Biological Chemistry. 273: 18930-18935. PMID 9668070 DOI: 10.1074/Jbc.273.30.18930 |
0.368 |
|
| 1998 |
Wickenden AD, Kaprielian R, Kassiri Z, Tsoporis JN, Tsushima R, Fishman GI, Backx PH. The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure. Cardiovascular Research. 37: 312-23. PMID 9614488 DOI: 10.1016/S0008-6363(97)00256-3 |
0.411 |
|
| 1998 |
Fishman GI. Timing Is Everything in Life: Conditional Transgene Expression in the Cardiovascular System Circulation Research. 82: 837-844. PMID 9576103 DOI: 10.1161/01.Res.82.8.837 |
0.37 |
|
| 1997 |
Bowman JC, Steinberg SF, Jiang T, Geenen DL, Fishman GI, Buttrick PM. Expression of Protein Kinase C Beta in the Heart Causes Hypertrophy in Adult Mice and Sudden Death in Neonates Journal of Clinical Investigation. 100: 2189-2195. PMID 9410895 DOI: 10.1172/Jci119755 |
0.434 |
|
| 1997 |
Sáez JC, Nairn AC, Czernik AJ, Fishman GI, Spray DC, Hertzberg EL. Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions. Journal of Molecular and Cellular Cardiology. 29: 2131-45. PMID 9281445 DOI: 10.1006/Jmcc.1997.0447 |
0.322 |
|
| 1997 |
McDonald TV, Yu Z, Ming Z, Palma E, Meyers MB, Wang KW, Goldstein SAN, Fishman GI. A minK–HERG complex regulates the cardiac potassium current I Kr Nature. 388: 289-292. PMID 9230439 DOI: 10.1038/40882 |
0.436 |
|
| 1996 |
Geimonen E, Jiang W, Ali M, Fishman GI, Garfield RE, Andersen J. Activation of protein kinase C in human uterine smooth muscle induces connexin-43 gene transcription through an AP-1 site in the promoter sequence. Journal of Biological Chemistry. 271: 23667-23674. PMID 8798588 DOI: 10.1074/Jbc.271.39.23667 |
0.309 |
|
| 1995 |
Fishman GI, Gao Y, Hertzberg EL, Spray DC. Reversible intercellular coupling by regulated expression of a gap junction channel gene. Cell Adhesion and Communication. 3: 353-65. PMID 8821036 DOI: 10.3109/15419069509081019 |
0.37 |
|
| 1995 |
Meyers MB, Pickel VM, Sheu SS, Sharma VK, Scotto KW, Fishman GI. Association of sorcin with the cardiac ryanodine receptor. The Journal of Biological Chemistry. 270: 26411-8. PMID 7592856 DOI: 10.1074/Jbc.270.44.26411 |
0.323 |
|
| 1995 |
Kwak BR, Sáez JC, Wilders R, Chanson M, Fishman GI, Hertzberg EL, Spray DC, Jongsma HJ. Effects of cGMP-dependent phosphorylation on rat and human connexin43 gap junction channels. Pflã¼Gers Archiv : European Journal of Physiology. 430: 770-8. PMID 7478932 DOI: 10.1007/Bf00386175 |
0.325 |
|
| 1995 |
Moreno AP, Fishman GI, Beyer EC, Spray DC. Voltage dependent gating and single channel analysis of heterotypic gap junction channels formed of Cx45 and Cx43 Progress in Cell Research. 4: 405-408. DOI: 10.1016/B978-0-444-81929-1.50083-6 |
0.32 |
|
| 1994 |
De Leon JR, Federoff HJ, Dickson DW, Vikstrom KL, Fishman GI. Cardiac and skeletal myopathy in beta myosin heavy-chain simian virus 40 tsA58 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 519-23. PMID 8290557 DOI: 10.1073/Pnas.91.2.519 |
0.414 |
|
| 1994 |
Fishman GI, Kaplan ML, Buttrick PM. Tetracycline-regulated cardiac gene expression in vivo. Journal of Clinical Investigation. 93: 1864-1868. PMID 8163686 DOI: 10.1172/Jci117174 |
0.387 |
|
| 1994 |
Leon JRD, Buttrick PM, Fishman GI. Functional analysis of the connexin43 gene promoter in vivo and in vitro. Journal of Molecular and Cellular Cardiology. 26: 379-389. PMID 8028021 DOI: 10.1006/Jmcc.1994.1047 |
0.423 |
|
| 1994 |
Passman RS, Fishman GI. Regulated expression of foreign genes in vivo after germline transfer. Journal of Clinical Investigation. 94: 2421-2425. PMID 7989599 DOI: 10.1172/Jci117609 |
0.4 |
|
| 1994 |
Moreno AP, Rook MB, Fishman GI, Spray DC. Gap junction channels: distinct voltage-sensitive and -insensitive conductance states. Biophysical Journal. 67: 113-9. PMID 7522596 DOI: 10.1016/S0006-3495(94)80460-6 |
0.326 |
|
| 1994 |
Moreno AP, Sáez JC, Fishman GI, Spray DC. Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation. Circulation Research. 74: 1050-7. PMID 7514508 DOI: 10.1161/01.Res.74.6.1050 |
0.364 |
|
| 1992 |
Fishman GI. Connexins and the heart Trends in Cardiovascular Medicine. 2: 50-55. PMID 21239274 DOI: 10.1016/1050-1738(92)90004-C |
0.425 |
|
| 1991 |
Fishman GI, Moreno AP, Spray DC, Leinwand LA. Functional analysis of human cardiac gap junction channel mutants. Proceedings of the National Academy of Sciences of the United States of America. 88: 3525-9. PMID 1850831 DOI: 10.1073/Pnas.88.9.3525 |
0.379 |
|
| 1991 |
Fishman GI, Hertzberg EL, Spray DC, Leinwand LA. Expression of connexin43 in the developing rat heart. Circulation Research. 68: 782-7. PMID 1660362 DOI: 10.1161/01.Res.68.3.782 |
0.459 |
|
| 1991 |
Fishman GI, Eddy RL, Shows TB, Rosenthal L, Leinwand LA. The human connexin gene family of gap junction proteins: Distinct chromosomal locations but similar structures Genomics. 10: 250-256. PMID 1646158 DOI: 10.1016/0888-7543(91)90507-B |
0.315 |
|
| 1990 |
Fishman GI, Spray DC, Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. The Journal of Cell Biology. 111: 589-98. PMID 1696265 DOI: 10.1083/Jcb.111.2.589 |
0.441 |
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