☰

Simon C. Johnson, Ph.D. - Publications

Affiliations: 
2013 Pathology University of Washington, Seattle, Seattle, WA 
Area:
Aging, Molecular Biology, Pathology
Tree Info Grants Similar researchers PubMed Report error

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bornstein R, Mulholland MT, Sedensky M, Morgan P, Johnson SC. Glutamine metabolism in diseases associated with mitochondrial dysfunction. Molecular and Cellular Neurosciences. 126: 103887. PMID 37586651 DOI: 10.1016/j.mcn.2023.103887  0.327
2022 Hanaford A, Johnson SC. The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence. Orphanet Journal of Rare Diseases. 17: 335. PMID 36056365 DOI: 10.1186/s13023-022-02495-3  0.314
2022 Gonzalez B, Tare A, Ryu S, Johnson SC, Atzmon G, Barzilai N, Kaeberlein M, Suh Y. High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity. Geroscience. PMID 35948858 DOI: 10.1007/s11357-022-00634-z  0.322
2021 Bornstein R, James K, Stokes J, Park KY, Kayser EB, Snell J, Bard A, Chen Y, Kalume F, Johnson SC. Differential effects of mTOR inhibition and dietary ketosis in a mouse model of subacute necrotizing encephalomyelopathy. Neurobiology of Disease. 105594. PMID 34933094 DOI: 10.1016/j.nbd.2021.105594  0.3
2020 Bornstein R, Gonzalez B, Johnson SC. Mitochondrial pathways in human health and aging. Mitochondrion. PMID 32738358 DOI: 10.1016/J.Mito.2020.07.007  0.489
2020 Johnson SC, Kayser EB, Bornstein R, Stokes J, Bitto A, Park KY, Pan A, Sun G, Raftery D, Kaeberlein M, Sedensky MM, Morgan PG. Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease. Molecular Genetics and Metabolism. PMID 32331968 DOI: 10.1016/J.Ymgme.2020.03.007  0.368
2019 Kahn-Kirby AH, Amagata A, Maeder CI, Mei JJ, Sideris S, Kosaka Y, Hinman A, Malone SA, Bruegger JJ, Wang L, Kim V, Shrader WD, Hoff KG, Latham JC, Ashley EA, ... ... Johnson SC, et al. Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy. Plos One. 14: e0214250. PMID 30921410 DOI: 10.1371/Journal.Pone.0214250  0.383
2018 Johnson SC. Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease. Sub-Cellular Biochemistry. 90: 49-97. PMID 30779006 DOI: 10.1007/978-981-13-2835-0_3  0.429
2018 Johnson SC, Pan A, Li L, Sedensky M, Morgan P. Neurotoxicity of anesthetics: Mechanisms and meaning from mouse intervention studies. Neurotoxicology and Teratology. PMID 30472095 DOI: 10.1016/J.Ntt.2018.11.004  0.327
2018 Johnson SC, Martinez F, Bitto A, Gonzalez B, Tazaerslan C, Cohen C, Delaval L, Timsit J, Knebelmann B, Terzi F, Mahal T, Zhu Y, Morgan PG, Sedensky MM, Kaeberlein M, et al. mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases. Kidney International. PMID 30471880 DOI: 10.1016/J.Kint.2018.08.038  0.436
2018 Venot Q, Blanc T, Rabia SH, Berteloot L, Ladraa S, Duong JP, Blanc E, Johnson SC, Hoguin C, Boccara O, Sarnacki S, Boddaert N, Pannier S, Martinez F, Magassa S, et al. Targeted therapy in patients with PIK3CA-related overgrowth syndrome. Nature. PMID 29899452 DOI: 10.1038/S41586-018-0217-9  0.335
2016 Johnson SC, Gonzalez B, Zhang Q, Milholland B, Zhang Z, Suh Y. Network analysis of mitonuclear GWAS reveals functional networks and tissue expression profiles of disease-associated genes. Human Genetics. PMID 27704213 DOI: 10.1007/S00439-016-1736-9  0.351
2016 Johnson SC, Kaeberlein M. Rapamycin in aging and disease: maximizing efficacy while minimizing side effects. Oncotarget. PMID 27384492 DOI: 10.18632/Oncotarget.10381  0.368
2015 McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, ... ... Johnson SC, et al. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metabolism. PMID 26456335 DOI: 10.1016/J.Cmet.2015.09.008  0.365
2015 Johnson SC, Yanos ME, Bitto A, Castanza A, Gagnidze A, Gonzalez B, Gupta K, Hui J, Jarvie C, Johnson BM, Letexier N, McCanta L, Sangesland M, Tamis O, Uhde L, et al. Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice. Frontiers in Genetics. 6: 247. PMID 26257774 DOI: 10.3389/Fgene.2015.00247  0.517
2015 Johnson SC, Dong X, Vijg J, Suh Y. Genetic evidence for common pathways in human age-related diseases. Aging Cell. PMID 26077337 DOI: 10.1111/Acel.12362  0.436
2015 Johnson SC, Sangesland M, Kaeberlein M, Rabinovitch PS. Modulating mTOR in aging and health. Interdisciplinary Topics in Gerontology. 40: 107-27. PMID 25341517 DOI: 10.1159/000364974  0.523
2014 Johnson SC. Translational Medicine. A target for pharmacological intervention in an untreatable human disease. Science (New York, N.Y.). 346: 1192. PMID 25477449 DOI: 10.1126/Science.Aaa1811  0.398
2013 Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, et al. mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science (New York, N.Y.). 342: 1524-8. PMID 24231806 DOI: 10.1126/Science.1244360  0.579
2013 Johnson SC, Martin GM, Rabinovitch PS, Kaeberlein M. Preserving youth: does rapamycin deliver? Science Translational Medicine. 5: 211fs40. PMID 24225941 DOI: 10.1126/Scitranslmed.3007316  0.486
2013 Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, et al. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell. 12: 1050-61. PMID 23837470 DOI: 10.1111/Acel.12130  0.551
2013 Johnson SC, Rabinovitch PS, Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature. 493: 338-45. PMID 23325216 DOI: 10.1038/Nature11861  0.559
2013 Kayser E, Johnson SC, Kaeberlein MR, Sedensky MM, Morgan PG. Capacity for oxidative phosphorylation does not decline with age in mitochondria from ndufs4 knockout mice Mitochondrion. 13: 915. DOI: 10.1016/J.Mito.2013.07.045  0.377
2012 Johnson S, Rabinovitch P. Ex Vivo Imaging of Excised Tissue Using Vital Dyes and Confocal Microscopy Current Protocols in Immunology. 61. PMID 22752953 DOI: 10.1002/0471142956.Cy0939S61  0.423
2012 Dai DF, Chen T, Johnson SC, Szeto H, Rabinovitch PS. Cardiac aging: from molecular mechanisms to significance in human health and disease. Antioxidants & Redox Signaling. 16: 1492-526. PMID 22229339 DOI: 10.1089/Ars.2011.4179  0.658
2011 Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS. Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circulation Research. 108: 837-46. PMID 21311045 DOI: 10.1161/Circresaha.110.232306  0.631
Show low-probability matches.