☰

Rubin M. Tuder - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology, Pathology
Tree Info Grants Similar researchers PubMed Report error

310 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Tuder RM, Gandjeva A, Williams S, Kumar S, Kheyfets VO, Hatton-Jones KM, Starr JR, Yun J, Hong J, West NP, Stenmark KR. Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 38568479 DOI: 10.1164/rccm.202307-1310OC  0.402
2023 Staquicini DI, Cardó-Vila M, Rotolo JA, Staquicini FI, Tang FHF, Smith TL, Ganju A, Schiavone C, Dogra P, Wang Z, Cristini V, Giordano RJ, Ozawa MG, Driessen WHP, Proneth B, ... ... Tuder RM, et al. Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220269120. PMID 37579172 DOI: 10.1073/pnas.2220269120  0.31
2023 Li M, Plecitá-Hlavatá L, Dobrinskikh E, McKeon BA, Gandjeva A, Riddle S, Laux A, Prasad RR, Kumar S, Tuder RM, Zhang H, Hu CJ, Stenmark KR. SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 37343939 DOI: 10.1165/rcmb.2022-0360OC  0.308
2023 Hu CJ, Laux A, Gandjeva A, Wang L, Li M, Brown D, Riddle S, Kheyfets VO, Tuder RM, Zhang H, Stenmark KR. The Effect of HIF Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 36944195 DOI: 10.1165/rcmb.2022-0114OC  0.311
2023 Hong J, Wong B, Rhodes CJ, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Montani D, Morrell NW, Wilkins MR, Nichols WC, ... ... Tuder RM, et al. Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension. Biorxiv : the Preprint Server For Biology. PMID 36712057 DOI: 10.1101/2023.01.12.523812  0.32
2022 Vohwinkel CU, Burns N, Coit E, Yuan X, Vladar EK, Sul C, Schmidt EP, Carmeliet P, Stenmark K, Nozik ES, Tuder RM, Eltzschig HK. HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury. Jci Insight. PMID 36326834 DOI: 10.1172/jci.insight.157855  0.314
2022 Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, ... ... Tuder RM, et al. Contribution of Fatty Acid Oxidation to the Pathogenesis of Pulmonary Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 35763400 DOI: 10.1152/ajplung.00039.2022  0.405
2022 Mickael C, Kheyfets VO, Langouët-Astrié C, Lee MH, Sanders LA, Trentin CO, Sweatt AJ, Zamanian RT, Bull TM, Stenmark K, Graham BB, Tuder RM. Peripheral Blood Inflammation Profile of Patients with Pulmonary Arterial Hypertension Using the High-Throughput Olink Proteomics Platform. American Journal of Respiratory Cell and Molecular Biology. 66: 580-581. PMID 35486078 DOI: 10.1165/rcmb.2021-0369LE  0.32
2022 Kassa B, Lee MH, Kumar R, Mickael C, Sanders L, Tuder RM, Mentink-Kane M, Graham BB. Experimental Schistosoma japonicum-induced pulmonary hypertension. Plos Neglected Tropical Diseases. 16: e0010343. PMID 35417453 DOI: 10.1371/journal.pntd.0010343  0.355
2021 Sitapara R, Lam TT, Gandjeva A, Tuder RM, Zisman LS. Phosphoproteomic analysis of lung tissue from patients with pulmonary arterial hypertension. Pulmonary Circulation. 11: 20458940211031109. PMID 34966541 DOI: 10.1177/20458940211031109  0.303
2021 Kassa B, Kumar R, Mickael C, Sanders L, Vohwinkel CU, Lee M, Gu S, Poth JM, Stenmark KR, Zhao YY, Tuder RM, Graham BB. Endothelial Cell PHD2-HIF1α-PFKFB3 Contributes to Right Ventricle Vascular Adaptation in Pulmonary Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 34346780 DOI: 10.1152/ajplung.00351.2020  0.354
2021 Vohwinkel CU, Coit EJ, Burns N, Elajaili H, Hernandez-Saavedra D, Yuan X, Eckle T, Nozik E, Tuder RM, Eltzschig HK. Targeting alveolar-specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21468. PMID 33687752 DOI: 10.1096/fj.202002778R  0.324
2021 Redente EF, Black BP, Backos DS, Bahadur AN, Humphries SM, Lynch DA, Tuder RM, Zemans RL, Riches DW. Persistent, Progressive Pulmonary Fibrosis and Epithelial Remodeling in Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 33406369 DOI: 10.1165/rcmb.2020-0542MA  0.404
2020 Delaney C, Davizon-Castillo P, Allawzi A, Posey J, Gandjeva A, Neeves K, Tuder RM, Di Paola J, Stenmark KR, Nozik ES. Platelet activation contributes to hypoxia-induced inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 33264579 DOI: 10.1152/ajplung.00519.2020  0.339
2020 Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, ... ... Tuder R, et al. Epithelial cell-specific loss of function of causes a spontaneous COPD-like phenotype and up-regulates expression in mice. Science Advances. 6: eabb7238. PMID 32851183 DOI: 10.1126/Sciadv.Abb7238  0.478
2020 Pasupneti S, Tian W, Tu AB, Dahms P, Granucci E, Gandjeva A, Xiang M, Butcher E, Semenza GL, Tuder R, Jiang X, Nicolls MR. Endothelial HIF-2α as a Key Endogenous Mediator Preventing Emphysema. American Journal of Respiratory and Critical Care Medicine. PMID 32515984 DOI: 10.1164/Rccm.202001-0078Oc  0.375
2020 Hume PS, Gibbings SL, Jakubzick CV, Tuder RM, Curran-Everett D, Henson PM, Smith BJ, Janssen WJ. Localization of Macrophages in the Human Lung via Design-Based Stereology. American Journal of Respiratory and Critical Care Medicine. PMID 32197050 DOI: 10.1164/Rccm.201911-2105Oc  0.407
2020 Tuder RM, Stenmark KR. Perspective: Pathobiological paradigms in pulmonary hypertension, time for reappraisal. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32186206 DOI: 10.1152/Ajplung.00067.2020  0.472
2020 Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB. Publisher Correction: Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Scientific Reports. 10: 4349. PMID 32132567 DOI: 10.1038/S41598-020-60500-W  0.451
2020 Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, Alessandro A, Stenmark KR, Tuder RM, Graham BB. Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Scientific Reports. 10: 413. PMID 31942023 DOI: 10.1038/S41598-019-57200-5  0.361
2020 Hashimoto R, Lanier GM, Dhagia V, Joshi S, Jordan A, Waddell I, Tuder RM, Stenmark KR, Wolin MS, McMurtry IF, Gupte SA. Pluripotent HSCs Augment a-Adrenergic Receptor-Mediated Contraction of Pulmonary Artery and Contribute to the Pathogenesis of Pulmonary Hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31913656 DOI: 10.1152/Ajplung.00327.2019  0.511
2020 Vohwinkel C, Roy R, Allawzi A, Burns N, Tuder RM, Grayck EN. Metabolic cross‐talk between alveolar type 2 cells and resident alveolar macrophages attenuates inflammation in acute lung injury The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01946  0.384
2019 Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Interstitial Macrophage-Derived Thrombospondin-1 Contributes to Hypoxia-Induced Pulmonary Hypertension. Cardiovascular Research. PMID 31710666 DOI: 10.1093/Cvr/Cvz304  0.379
2019 Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, et al. Immunoglobulin-Driven Complement Activation Regulates Pro-Inflammatory Remodeling in Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 31545648 DOI: 10.1164/Rccm.201903-0591Oc  0.424
2019 Zhang Y, Jiang M, Nouraie M, Roth MG, Tabib T, Winters S, Chen X, Sembrat J, Chu Y, Cardenes N, Tuder RM, Herzog EL, Ryu C, Rojas M, Lafyatis R, et al. GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31432710 DOI: 10.1152/Ajplung.00062.2019  0.51
2019 Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB. Th2 CD4 T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension. Journal of the American Heart Association. 8: e013111. PMID 31339057 DOI: 10.1161/Jaha.119.013111  0.348
2019 Tuder RM, Cool CD. Pulmonary Arteries and Microcirculation in COPD With Pulmonary Hypertension: Bystander or Culprit? Chest. 156: 4-6. PMID 31279376 DOI: 10.1016/J.Chest.2019.04.100  0.489
2019 Mickael C, Kumar R, Hernandez-Saavedra D, Kassa B, Sanders L, Koyanagi D, Gu S, Lee MH, Tuder RM, Graham BB. IL-6Ra in Smooth Muscle Cells Protects against - and Hypoxia-induced Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. 61: 123-126. PMID 31259624 DOI: 10.1165/Rcmb.2018-0277Le  0.383
2019 Atif SM, Mack DG, McKee AS, Rangel-Moreno J, Martin AK, Getahun A, Maier LA, Cambier JC, Tuder R, Fontenot AP. Protective role of B cells in sterile particulate-induced lung injury. Jci Insight. 5. PMID 31094704 DOI: 10.1172/Jci.Insight.125494  0.391
2019 Ebenezer DL, Berdyshev EV, Bronova IA, Liu Y, Tiruppathi C, Komarova Y, Benevolenskaya EV, Suryadevara V, Ha AW, Harijith A, Tuder RM, Natarajan V, Fu P. stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury. Thorax. PMID 30723184 DOI: 10.1136/Thoraxjnl-2018-212378  0.376
2018 Tuder RM. Bringing Light to Chronic Obstructive Pulmonary Disease Pathogenesis and Resilience. Annals of the American Thoracic Society. 15: S227-S233. PMID 30759011 DOI: 10.1513/Annalsats.201808-583Mg  0.449
2018 Stearman RS, Bui QM, Speyer G, Handen A, Cornelius AR, Graham BB, Kim S, Mickler EA, Tuder RM, Chan SY, Geraci MW. Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome. American Journal of Respiratory Cell and Molecular Biology. PMID 30562042 DOI: 10.1165/Rcmb.2018-0368Oc  0.497
2018 Kassa BG, Mickael C, Kumar R, Sanders L, Koyanagi D, Hernandez-Saavedra D, Tuder R, Graham B. EXPRESS: Paclitaxel Blocks Th2-Mediated TGF-β Activation in Schistosoma mansoni-Induced Pulmonary Hypertension. Pulmonary Circulation. 2045894018820813. PMID 30511588 DOI: 10.1177/2045894018820813  0.363
2018 Lin CR, Bahmed K, Criner GJ, Marchetti N, Tuder RM, Kelsen S, Bolla S, Mandapati C, Kosmider B. S100A8 Protects Human Primary Alveolar Type II Cells Against Injury and Emphysema. American Journal of Respiratory Cell and Molecular Biology. PMID 30277795 DOI: 10.1165/Rcmb.2018-0144Oc  0.368
2018 Krafsur GM, Neary J, Garry F, Timothy H, Gould D, Mason G, Thomas MG, Enns MR, Tuder R, Brown D, Stenmark KR. EXPRESS: Cardiopulmonary Remodeling in Fattened Beef Cattle: A Naturally Occurring Large Animal Model of Obesity-Associated Pulmonary Hypertension with Left Heart Disease. Pulmonary Circulation. 2045894018796804. PMID 30124135 DOI: 10.1177/2045894018796804  0.391
2018 Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, et al. Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement. American Journal of Respiratory and Critical Care Medicine. 198: e15-e43. PMID 30109950 DOI: 10.1164/Rccm.201806-1160St  0.329
2018 Gandjeva A, Tuder RM. Lung Histological Methods. Methods in Molecular Biology (Clifton, N.J.). 1809: 315-329. PMID 29987797 DOI: 10.1007/978-1-4939-8570-8_20  0.386
2018 Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, ... ... Tuder RM, et al. Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 29851508 DOI: 10.1165/Rcmb.2018-0095Oc  0.428
2018 Bamberg A, Redente EF, Groshong SD, Tuder RM, Cool CD, Keith RC, Edelman BL, Black BP, Cosgrove GP, Wynes MW, Curran-Everett D, De Langhe S, Ortiz LA, Thorburn A, Riches DWH. Protein Tyrosine Phosphatase-N13 (PTPN13) Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 29727583 DOI: 10.1164/Rccm.201707-1497Oc  0.486
2018 Stenmark KR, Tuder RM. Peroxisome Proliferator-activated Receptor γ and Mitochondria: Drivers or Passengers on the Road to Pulmonary Hypertension? American Journal of Respiratory Cell and Molecular Biology. 58: 555-557. PMID 29714631 DOI: 10.1165/Rcmb.2017-0318Ed  0.433
2018 Haeger SM, Liu X, Han X, McNeil JB, Oshima K, McMurtry SA, Yang Y, Ouyang Y, Zhang F, Nozik-Grayck E, Zemans RL, Tuder RM, Bastarache JA, Linhardt RJ, Schmidt EP. Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and is Shed During Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 29584451 DOI: 10.1165/Rcmb.2017-0428Oc  0.428
2018 Jansing NL, Patel N, McClendon J, Redente EF, Henson PM, Tuder RM, Hyde DM, Nyengaard JR, Zemans RL. Flow Cytometry Underestimates and Planimetry Overestimates Alveolar Epithelial Type 2 Cell Expansion after Lung Injury. American Journal of Respiratory and Critical Care Medicine. PMID 29533675 DOI: 10.1164/Rccm.201709-1838Le  0.369
2018 Stenmark KR, Frid MG, Graham BB, Tuder RM. Dynamic and Diverse Changes in the Functional Properties of Vascular Smooth Muscle Cells in Pulmonary Hypertension. Cardiovascular Research. PMID 29385432 DOI: 10.1093/Cvr/Cvy004  0.454
2017 Hernandez-Saavedra D, Swain K, Tuder R, Petersen SV, Nozik-Grayck E. Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation. Advances in Experimental Medicine and Biology. 967: 57-70. PMID 29047081 DOI: 10.1007/978-3-319-63245-2_5  0.374
2017 Zamanian RT, Hedlin H, Greuenwald P, Wilson DM, Segal JI, Jorden M, Kudelko K, Liu J, Hsi A, Rupp A, Sweatt AJ, Tuder R, Berry GJ, Rabinovitch M, Doyle RL, et al. Features and Outcomes of Methamphetamine Associated Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 28934596 DOI: 10.1164/Rccm.201705-0943Oc  0.42
2017 McClendon J, Jansing NL, Redente EF, Gandjeva A, Ito Y, Colgan SP, Ahmad A, Riches DWH, Chapman HA, Mason RJ, Tuder RM, Zemans RL. Hypoxia-Inducible Factor 1α Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury. The American Journal of Pathology. PMID 28618253 DOI: 10.1016/J.Ajpath.2017.04.012  0.422
2017 Jansing NL, McClendon J, Henson PM, Tuder RM, Hyde DM, Zemans RL. Unbiased Quantitation of ATII to ATI Cell Transdifferentiation During Repair After Lung Injury in Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 28586241 DOI: 10.1165/Rcmb.2017-0037Ma  0.381
2017 Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, ... ... Tuder RM, et al. TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. Nature Communications. 8: 15494. PMID 28555642 DOI: 10.1038/Ncomms15494  0.393
2017 Budinger GS, Kohanski RA, Gan W, Kobor MS, Amaral LA, Armanios M, Kelsey KT, Pardo A, Tuder R, Macian F, Chandel N, Vaughan D, Rojas M, Mora AL, Kovacs E, et al. The Intersection Of Aging Biology and The Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28498894 DOI: 10.1093/Gerona/Glx090  0.422
2017 Graham BB, Koyanagi D, Kandasamy B, Tuder RM. Right Ventricle Vasculature in Human Pulmonary Hypertension Assessed by Stereology. American Journal of Respiratory and Critical Care Medicine. PMID 28278380 DOI: 10.1164/Rccm.201702-0425Le  0.446
2016 Tuder RM. Pulmonary vascular remodeling in pulmonary hypertension. Cell and Tissue Research. PMID 28025704 DOI: 10.1007/S00441-016-2539-Y  0.525
2016 Hernández-Saavedra D, Sanders L, Perez MJ, Kosmider B, Smith LP, Mitchell JD, Yoshida T, Tuder RM. RTP801 Amplifies Nox-4-dependent Oxidative Stress Induced by Cigarette Smoke. American Journal of Respiratory Cell and Molecular Biology. PMID 27556956 DOI: 10.1165/Rcmb.2016-0144Oc  0.385
2016 Stenmark KR, Krafsur GM, Tuder RM. Pulmonary Veno-occlusive Disease and Pulmonary Hypertension in Dogs Striking Similarities to the Human Condition Veterinary Pathology. 53: 707-710. PMID 27298303 DOI: 10.1177/0300985816647454  0.495
2016 Xu W, Ghosh S, Comhair SA, Asosingh K, Janocha AJ, Mavrakis DA, Bennett CD, Gruca LL, Graham BB, Queisser KA, Kao CC, Wedes SH, Petrich JM, Tuder RM, Kalhan SC, et al. Increased mitochondrial arginine metabolism supports bioenergetics in asthma. The Journal of Clinical Investigation. PMID 27214549 DOI: 10.1172/Jci82925  0.327
2016 Wu D, Talbot CC, Liu Q, Jing ZC, Damico RL, Tuder R, Barnes KC, Hassoun PM, Gao L. Identifying microRNAs targeting Wnt/β-catenin pathway in end-stage idiopathic pulmonary arterial hypertension. Journal of Molecular Medicine (Berlin, Germany). PMID 27188753 DOI: 10.1007/S00109-016-1426-Z  0.315
2016 Kudryashova TV, Goncharov DA, Pena A, Kelly N, Vanderpool R, Baust J, Kobir A, Shufesky W, Mora AL, Morelli AE, Zhao J, Ihida-Stansbury K, Chang B, DeLisser H, Tuder RM, et al. HIPPO-integrin Linked Kinase Crosstalk Controls Self-sustaining Proliferation and Survival in Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 27119551 DOI: 10.1164/Rccm.201510-2003Oc  0.507
2016 Bahmed K, Messier EM, Zhou W, Tuder RM, Freed CR, Chu HW, Kelsen SG, Bowler RP, Mason RJ, Kosmider B. DJ-1 Modulates Nrf2-mediated Protection in Human Primary Alveolar Type II Cells in Smokers. American Journal of Respiratory Cell and Molecular Biology. PMID 27093578 DOI: 10.1165/Rcmb.2015-0304Oc  0.381
2015 Kumar R, Mickael C, Chabon J, Gebreab L, Rutebemberwa A, Rodriguez Garcia A, Koyanagi DE, Sanders L, Gandjeva A, Kearns MT, Barthel L, Janssen WJ, Mauad T, Bandeira A, Schmidt E, ... Tuder RM, et al. The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 26192556 DOI: 10.1164/Rccm.201410-1820Oc  0.448
2015 Stenmark KR, Tuder RM, El Kasmi KC. Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension. Journal of Applied Physiology (Bethesda, Md. : 1985). 119: 1164-72. PMID 25930027 DOI: 10.1152/Japplphysiol.00283.2015  0.401
2015 Alder JK, Barkauskas CE, Limjunyawong N, Stanley SE, Kembou F, Tuder RM, Hogan BL, Mitzner W, Armanios M. Telomere dysfunction causes alveolar stem cell failure. Proceedings of the National Academy of Sciences of the United States of America. 112: 5099-104. PMID 25840590 DOI: 10.1073/Pnas.1504780112  0.452
2015 Drake KM, Comhair SA, Erzurum SC, Tuder RM, Aldred MA. Endothelial chromosome 13 deletion in congenital heart disease-associated pulmonary arterial hypertension dysregulates SMAD9 signaling. American Journal of Respiratory and Critical Care Medicine. 191: 850-4. PMID 25830521 DOI: 10.1164/Rccm.201411-1985Le  0.352
2015 Thannickal VJ, Murthy M, Balch WE, Chandel NS, Meiners S, Eickelberg O, Selman M, Pardo A, White ES, Levy BD, Busse PJ, Tuder RM, Antony VB, Sznajder JI, Budinger GR. Blue journal conference. Aging and susceptibility to lung disease. American Journal of Respiratory and Critical Care Medicine. 191: 261-9. PMID 25590812 DOI: 10.1164/Rccm.201410-1876Pp  0.383
2015 McClendon J, Redente EF, Ito Y, Colgan SP, Ahmad A, Tuder R, Mason RJ, Henson PM, Zemans RL. Hypoxia-Inducible Factor–Dependent CXCR4/SDF1 Signaling Promotes Alveolar Type II Cell Spreading and the Resolution of Epithelial Permeability after Lung Injury Annals of the American Thoracic Society. 12: S72-S73. DOI: 10.1513/Annalsats.201411-545Mg  0.398
2014 Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. [Relevant issues in the pathology and pathobiology of pulmonary hypertension]. TüRk Kardiyoloji DerneğI ArşIvi : TüRk Kardiyoloji DerneğInin YayıN OrganıDıR. 42: 5-16. PMID 25697030  0.379
2014 Cavasin MA, Demos-Davies KM, Schuetze KB, Blakeslee WW, Stratton MS, Tuder RM, McKinsey TA. Reversal of severe angioproliferative pulmonary arterial hypertension and right ventricular hypertrophy by combined phosphodiesterase-5 and endothelin receptor inhibition. Journal of Translational Medicine. 12: 314. PMID 25425003 DOI: 10.1186/S12967-014-0314-Y  0.457
2014 Rutebemberwa A, Stevens MJ, Perez MJ, Smith LP, Sanders L, Cosgrove G, Robertson CE, Tuder RM, Harris JK. Novosphingobium and its potential role in chronic obstructive pulmonary diseases: insights from microbiome studies. Plos One. 9: e111150. PMID 25340840 DOI: 10.1371/Journal.Pone.0111150  0.444
2014 Yunt ZX, Mohning MP, Barthel L, Kearns MT, Tuder RM, Hyde DM, Henson PM, Janssen WJ. Kinetics of the angiogenic response in lung endothelium following acute inflammatory injury with bleomycin Experimental Lung Research. 40: 415-425. PMID 25153689 DOI: 10.3109/01902148.2014.938202  0.443
2014 Nadon AM, Perez MJ, Hernandez-Saavedra D, Smith LP, Yang Y, Sanders LA, Gandjeva A, Chabon J, Koyanagi DE, Graham BB, Tuder RM, Schmidt EP. Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation. The American Journal of Pathology. 184: 2382-9. PMID 25016184 DOI: 10.1016/J.Ajpath.2014.06.002  0.438
2014 Chabon JJ, Gebreab L, Kumar R, Debella E, Tanaka T, Koyanagi D, Rodriguez Garcia A, Sanders L, Perez M, Tuder RM, Graham BB. Role of vascular endothelial growth factor signaling in Schistosoma-induced experimental pulmonary hypertension. Pulmonary Circulation. 4: 289-99. PMID 25006448 DOI: 10.1086/675992  0.457
2014 Robinson JC, Graham BB, Rouault TC, Tuder RM. The crossroads of iron with hypoxia and cellular metabolism. Implications in the pathobiology of pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 51: 721-9. PMID 24988529 DOI: 10.1165/Rcmb.2014-0021Tr  0.428
2014 El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, et al. Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension. Journal of Immunology (Baltimore, Md. : 1950). 193: 597-609. PMID 24928992 DOI: 10.4049/Jimmunol.1303048  0.352
2014 Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proceedings of the National Academy of Sciences of the United States of America. 111: 8553-8. PMID 24912188 DOI: 10.1073/Pnas.1408048111  0.311
2014 Tuder RM. How do we measure pathology in PAH (lung and RV) and what does it tell us about the disease. Drug Discovery Today. 19: 1257-63. PMID 24881780 DOI: 10.1016/J.Drudis.2014.05.022  0.481
2014 Lahm T, Tuder RM, Petrache I. Progress in solving the sex hormone paradox in pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L7-26. PMID 24816487 DOI: 10.1152/Ajplung.00337.2013  0.387
2014 Dahlman JE, Barnes C, Khan OF, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, ... ... Tuder RM, et al. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nature Nanotechnology. 9: 648-55. PMID 24813696 DOI: 10.1038/Nnano.2014.84  0.314
2014 Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, et al. Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 189: 1110-20. PMID 24605778 DOI: 10.1164/Rccm.201309-1697Oc  0.432
2014 Dweik RA, Rounds S, Erzurum SC, Archer S, Fagan K, Hassoun PM, Hill NS, Humbert M, Kawut SM, Krowka M, Michelakis E, Morrell NW, Stenmark K, Tuder RM, Newman J, et al. An official American Thoracic Society Statement: pulmonary hypertension phenotypes. American Journal of Respiratory and Critical Care Medicine. 189: 345-55. PMID 24484330 DOI: 10.1164/Rccm.201311-1954St  0.335
2014 Tuder RM, Robinson JC, Graham BB. Fat and cardiotoxicity in hereditary pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 189: 247-9. PMID 24484329 DOI: 10.1164/Rccm.201312-2240Ed  0.502
2014 Goncharov DA, Kudryashova TV, Ziai H, Ihida-Stansbury K, DeLisser H, Krymskaya VP, Tuder RM, Kawut SM, Goncharova EA. Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension. Circulation. 129: 864-74. PMID 24270265 DOI: 10.1161/Circulationaha.113.004581  0.469
2014 Rutebemberwa A, Stevens M, Perez M, Smith L, Sanders L, Tuder R, Harris JK. Novosphingobiumspp. in Chronic Obstructive Pulmonary Disease in Humans and Subacute Lung Inflammation in Mice Annals of the American Thoracic Society. 11: S76-S77. DOI: 10.1513/Annalsats.201306-207Mg  0.482
2013 Lygizos MI, Yang Y, Altmann CJ, Okamura K, Hernando AA, Perez MJ, Smith LP, Koyanagi DE, Gandjeva A, Bhargava R, Tuder RM, Faubel S, Schmidt EP. Heparanase mediates renal dysfunction during early sepsis in mice. Physiological Reports. 1: e00153. PMID 24400155 DOI: 10.1002/Phy2.153  0.353
2013 Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. Relevant issues in the pathology and pathobiology of pulmonary hypertension. Journal of the American College of Cardiology. 62: D4-12. PMID 24355640 DOI: 10.1016/J.Jacc.2013.10.025  0.48
2013 Tuder RM, Stacher E, Robinson J, Kumar R, Graham BB. Pathology of pulmonary hypertension. Clinics in Chest Medicine. 34: 639-50. PMID 24267295 DOI: 10.1016/j.ccm.2013.08.009  0.463
2013 Hunt JM, Bethea B, Liu X, Gandjeva A, Mammen PP, Stacher E, Gandjeva MR, Parish E, Perez M, Smith L, Graham BB, Kuebler WM, Tuder RM. Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L725-36. PMID 24039255 DOI: 10.1152/Ajplung.00186.2013  0.547
2013 Graham BB, Chabon J, Gebreab L, Poole J, Debella E, Davis L, Tanaka T, Sanders L, Dropcho N, Bandeira A, Vandivier RW, Champion HC, Butrous G, Wang XJ, Wynn TA, ... Tuder RM, et al. Transforming growth factor-β signaling promotes pulmonary hypertension caused by Schistosoma mansoni. Circulation. 128: 1354-64. PMID 23958565 DOI: 10.1161/Circulationaha.113.003072  0.43
2013 Dengler V, Downey GP, Tuder RM, Eltzschig HK, Schmidt EP. Neutrophil intercellular communication in acute lung injury. Emerging roles of microparticles and gap junctions. American Journal of Respiratory Cell and Molecular Biology. 49: 1-5. PMID 23815257 DOI: 10.1165/Rcmb.2012-0472Tr  0.374
2013 Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM. Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 49: 951-9. PMID 23815102 DOI: 10.1165/Rcmb.2012-0532Oc  0.464
2013 Solomon JJ, Ryu JH, Tazelaar HD, Myers JL, Tuder R, Cool CD, Curran-Everett D, Fischer A, Swigris JJ, Brown KK. Fibrosing interstitial pneumonia predicts survival in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Respiratory Medicine. 107: 1247-52. PMID 23791462 DOI: 10.1016/J.Rmed.2013.05.002  0.334
2013 Messier EM, Bahmed K, Tuder RM, Chu HW, Bowler RP, Kosmider B. Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke. Cell Death & Disease. 4: e573. PMID 23559007 DOI: 10.1038/Cddis.2013.96  0.388
2013 Lockett AD, Kimani S, Ddungu G, Wrenger S, Tuder RM, Janciauskiene SM, Petrache I. α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α. American Journal of Respiratory Cell and Molecular Biology. 49: 143-50. PMID 23526215 DOI: 10.1165/Rcmb.2012-0515Oc  0.377
2013 Lundgrin EL, Park MM, Sharp J, Tang WH, Thomas JD, Asosingh K, Comhair SA, DiFilippo FP, Neumann DR, Davis L, Graham BB, Tuder RM, Dostanic I, Erzurum SC. Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year. Annals of the American Thoracic Society. 10: 1-9. PMID 23509326 DOI: 10.1513/Annalsats.201206-029Oc  0.336
2013 Messier EM, Day BJ, Bahmed K, Kleeberger SR, Tuder RM, Bowler RP, Chu HW, Mason RJ, Kosmider B. N-acetylcysteine protects murine alveolar type II cells from cigarette smoke injury in a nuclear erythroid 2-related factor-2-independent manner. American Journal of Respiratory Cell and Molecular Biology. 48: 559-67. PMID 23492188 DOI: 10.1165/Rcmb.2012-0295Oc  0.39
2013 Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, et al. Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. Cell Metabolism. 17: 271-81. PMID 23395173 DOI: 10.1016/J.Cmet.2012.12.016  0.373
2013 Kamocki K, Van Demark M, Fisher A, Rush NI, Presson RG, Hubbard W, Berdyshev EV, Adamsky S, Feinstein E, Gandjeva A, Tuder RM, Petrache I. RTP801 is required for ceramide-induced cell-specific death in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 48: 87-93. PMID 23024063 DOI: 10.1165/Rcmb.2012-0254Oc  0.45
2012 Tuder RM, Lara AR, Thannickal VJ. Lactate, a novel trigger of transforming growth factor-β activation in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 186: 701-3. PMID 23071184 DOI: 10.1164/Rccm.201208-1491Ed  0.379
2012 Tuder RM, Petrache I. Pathogenesis of chronic obstructive pulmonary disease. The Journal of Clinical Investigation. 122: 2749-55. PMID 22850885 DOI: 10.1172/Jci60324  0.44
2012 Schmidt EP, Yang Y, Janssen WJ, Gandjeva A, Perez MJ, Barthel L, Zemans RL, Bowman JC, Koyanagi DE, Yunt ZX, Smith LP, Cheng SS, Overdier KH, Thompson KR, Geraci MW, ... ... Tuder RM, et al. The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nature Medicine. 18: 1217-23. PMID 22820644 DOI: 10.1038/Nm.2843  0.474
2012 Lara AR, Cosgrove GP, Janssen WJ, Huie TJ, Burnham EL, Heinz DE, Curran-Everett D, Sahin H, Schwarz MI, Cool CD, Groshong SD, Geraci MW, Tuder RM, Hyde DM, Henson PM. Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia Chest. 142: 1569-1576. PMID 22797508 DOI: 10.1378/Chest.12-0029  0.338
2012 Asosingh K, Farha S, Lichtin A, Graham B, George D, Aldred M, Hazen SL, Loyd J, Tuder R, Erzurum SC. Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension. Blood. 120: 1218-27. PMID 22745307 DOI: 10.1182/Blood-2012-03-419275  0.473
2012 Hunt JM, Tuder R. Alpha 1 anti-trypsin: one protein, many functions. Current Molecular Medicine. 12: 827-35. PMID 22697349 DOI: 10.2174/156652412801318755  0.425
2012 Stacher E, Graham BB, Hunt JM, Gandjeva A, Groshong SD, McLaughlin VV, Jessup M, Grizzle WE, Aldred MA, Cool CD, Tuder RM. Modern age pathology of pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 186: 261-72. PMID 22679007 DOI: 10.1164/Rccm.201201-0164Oc  0.488
2012 Tuder RM, Kern JA, Miller YE. Senescence in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 9: 62-3. PMID 22550244 DOI: 10.1513/pats.201201-012MS  0.344
2012 Kearns MT, Dalal S, Horstmann SA, Richens TR, Tanaka T, Doe JM, Boe DM, Voelkel NF, Taraseviciene-Stewart L, Janssen WJ, Lee CG, Elias JA, Bratton D, Tuder RM, Henson PM, et al. Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L711-8. PMID 22307908 DOI: 10.1152/Ajplung.00116.2011  0.396
2012 Podowski M, Calvi C, Metzger S, Misono K, Poonyagariyagorn H, Lopez-Mercado A, Ku T, Lauer T, McGrath-Morrow S, Berger A, Cheadle C, Tuder R, Dietz HC, Mitzner W, Wise R, et al. Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice. The Journal of Clinical Investigation. 122: 229-40. PMID 22182843 DOI: 10.1172/Jci46215  0.437
2012 Tuder RM, Davis LA, Graham BB. Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 185: 260-6. PMID 22077069 DOI: 10.1164/Rccm.201108-1536Pp  0.499
2012 Heath A, Alvensleben I, Graham B, Albrecht E, Brockmann C, Tuder R. Project 5: Does High Altitude Protect Against Irreversible Pulmonary Hypertension? Pvri Review. 4: 52. DOI: 10.4103/0974-6013.104648  0.43
2012 Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AO, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice (Journal of Clinical Investigation (2011) 121, 6 (2470-2479) DOI: 10.1172/JCI43881) Journal of Clinical Investigation. 122: 2703. DOI: 10.1172/Jci64369  0.374
2011 Graham BB, Chabon J, Bandeira A, Espinheira L, Butrous G, Tuder RM. Significant intrapulmonary Schistosoma egg antigens are not present in schistosomiasis-associated pulmonary hypertension. Pulmonary Circulation. 1: 456-61. PMID 22530100 DOI: 10.4103/2045-8932.93544  0.496
2011 Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. The Journal of Clinical Investigation. 121: 4548-66. PMID 22005303 DOI: 10.1172/Jci57734  0.52
2011 Alder JK, Guo N, Kembou F, Parry EM, Anderson CJ, Gorgy AI, Walsh MF, Sussan T, Biswal S, Mitzner W, Tuder RM, Armanios M. Telomere length is a determinant of emphysema susceptibility. American Journal of Respiratory and Critical Care Medicine. 184: 904-12. PMID 21757622 DOI: 10.1164/Rccm.201103-0520Oc  0.42
2011 Pastukh VM, Zhang L, Ruchko MV, Gorodnya O, Bardwell GC, Tuder RM, Gillespie MN. Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences. International Journal of Chronic Obstructive Pulmonary Disease. 6: 209-17. PMID 21660298 DOI: 10.2147/Copd.S15922  0.377
2011 Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 121: 2470-9. PMID 21576822 DOI: 10.1172/Jci43881  0.476
2011 Winn RA, Tuder RM. "Un-slugging" resistance to epidermal growth factor receptor inhibition: A positive outlook for the future of lung cancer therapy American Journal of Respiratory and Critical Care Medicine. 183: 970-972. PMID 21498821 DOI: 10.1164/Rccm.201012-1970Ed  0.319
2011 Gebska MA, Stevenson BK, Hemnes AR, Bivalacqua TJ, Haile A, Hesketh GG, Murray CI, Zaiman AL, Halushka MK, Krongkaew N, Strong TD, Cooke CA, El-Haddad H, Tuder RM, Berkowitz DE, et al. Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity. Cardiovascular Research. 90: 353-63. PMID 21421555 DOI: 10.1093/Cvr/Cvq410  0.349
2011 Lee JE, Patel K, Almodóvar S, Tuder RM, Flores SC, Sehgal PB. Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1141-58. PMID 21217069 DOI: 10.1152/Ajpheart.00767.2010  0.459
2011 Meadows CA, Risbano MG, Zhang L, Geraci MW, Tuder RM, Collier DH, Bull TM. Increased expression of growth differentiation factor-15 in systemic sclerosis-associated pulmonary arterial hypertension. Chest. 139: 994-1002. PMID 20829333 DOI: 10.1378/Chest.10-0302  0.453
2011 Kolosionek E, Graham BB, Tuder RM, Butrous G. Pulmonary vascular disease associated with parasitic infection--the role of schistosomiasis. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 17: 15-24. PMID 20636425 DOI: 10.1111/J.1469-0691.2010.03308.X  0.484
2011 Filosto S, Castillo S, Danielson A, Franzi L, Khan E, Kenyon N, Last J, Pinkerton K, Tuder R, Goldkorn T. Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. American Journal of Respiratory Cell and Molecular Biology. 44: 350-60. PMID 20448054 DOI: 10.1165/Rcmb.2009-0422Oc  0.457
2010 Petrusca DN, Gu Y, Adamowicz JJ, Rush NI, Hubbard WC, Smith PA, Berdyshev EV, Birukov KG, Lee CH, Tuder RM, Twigg HL, Vandivier RW, Petrache I. Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. The Journal of Biological Chemistry. 285: 40322-32. PMID 20956540 DOI: 10.1074/Jbc.M110.137604  0.406
2010 Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, ... ... Tuder R, et al. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. American Journal of Respiratory and Critical Care Medicine. 182: 1554-62. PMID 20833821 DOI: 10.1164/Rccm.201006-0869Ws  0.461
2010 Graham BB, Mentink-Kane MM, El-Haddad H, Purnell S, Zhang L, Zaiman A, Redente EF, Riches DW, Hassoun PM, Bandeira A, Champion HC, Butrous G, Wynn TA, Tuder RM. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. The American Journal of Pathology. 177: 1549-61. PMID 20671265 DOI: 10.2353/Ajpath.2010.100063  0.35
2010 Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 182: 1153-60. PMID 20581168 DOI: 10.1164/Rccm.201003-0491Oc  0.476
2010 Graham BB, Bandeira AP, Morrell NW, Butrous G, Tuder RM. Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective. Chest. 137: 20S-29S. PMID 20522577 DOI: 10.1378/Chest.10-0048  0.444
2010 Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, Richter A, Brown E, Ashush H, Notkin N, Gelfand A, ... ... Tuder RM, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nature Medicine. 16: 767-73. PMID 20473305 DOI: 10.1038/Nm.2157  0.386
2010 Peng XQ, Damarla M, Skirball J, Nonas S, Wang XY, Han EJ, Hasan EJ, Cao X, Boueiz A, Damico R, Tuder RM, Sciuto AM, Anderson DR, Garcia JG, Kass DA, et al. Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogen-activated protein kinase in mouse lung. Acta Pharmacologica Sinica. 31: 175-83. PMID 20139900 DOI: 10.1038/Aps.2009.190  0.392
2010 Fijalkowska I, Xu W, Comhair SA, Janocha AJ, Mavrakis LA, Krishnamachary B, Zhen L, Mao T, Richter A, Erzurum SC, Tuder RM. Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells. The American Journal of Pathology. 176: 1130-8. PMID 20110409 DOI: 10.2353/Ajpath.2010.090832  0.423
2010 Geraci MW, Bull TM, Tuder RM. Genomics of pulmonary arterial hypertension: implications for therapy. Heart Failure Clinics. 6: 101-14. PMID 19945066 DOI: 10.1016/J.Hfc.2009.08.001  0.394
2010 Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation. American Journal of Respiratory Cell and Molecular Biology. 42: 524-36. PMID 19520915 DOI: 10.1165/Rcmb.2009-0054Oc  0.442
2009 Graham BB, Tuder RM. [Pathogenesis of pulmonary hypertension]. Zhonghua Yi Xue Za Zhi. 89: 2091-3. PMID 20058607  0.4
2009 Malhotra D, Thimmulappa R, Vij N, Navas-Acien A, Sussan T, Merali S, Zhang L, Kelsen SG, Myers A, Wise R, Tuder R, Biswal S. Expression of concern: Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. American Journal of Respiratory and Critical Care Medicine. 180: 1196-207. PMID 19797762 DOI: 10.1164/Rccm.200903-0324Oc  0.424
2009 D'Alessio FR, Tsushima K, Aggarwal NR, West EE, Willett MH, Britos MF, Pipeling MR, Brower RG, Tuder RM, McDyer JF, King LS. CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. The Journal of Clinical Investigation. 119: 2898-913. PMID 19770521 DOI: 10.1172/Jci36498  0.344
2009 MacNee W, Tuder RM. New paradigms in the pathogenesis of chronic obstructive pulmonary disease I. Proceedings of the American Thoracic Society. 6: 527-31. PMID 19741262 DOI: 10.1513/pats.200905-027DS  0.364
2009 Giordano RJ, Edwards JK, Tuder RM, Arap W, Pasqualini R. Combinatorial ligand-directed lung targeting. Proceedings of the American Thoracic Society. 6: 411-5. PMID 19687212 DOI: 10.1513/pats.200903-014AW  0.3
2009 Sehgal PB, Mukhopadhyay S, Patel K, Xu F, Almodóvar S, Tuder RM, Flores SC. Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L729-37. PMID 19648286 DOI: 10.1152/Ajplung.00087.2009  0.49
2009 Tuder RM. Pathology of pulmonary arterial hypertension. Seminars in Respiratory and Critical Care Medicine. 30: 376-85. PMID 19634077 DOI: 10.1055/S-0029-1233307  0.54
2009 Tuder RM, Abman SH, Braun T, Capron F, Stevens T, Thistlethwaite PA, Haworth SG. Development and pathology of pulmonary hypertension. Journal of the American College of Cardiology. 54: S3-9. PMID 19555856 DOI: 10.1016/J.Jacc.2009.04.009  0.532
2009 Podowski M, Calvi CL, Cheadle C, Tuder RM, Biswals S, Neptune ER. Complex integration of matrix, oxidative stress, and apoptosis in genetic emphysema. The American Journal of Pathology. 175: 84-96. PMID 19541933 DOI: 10.2353/Ajpath.2009.080870  0.352
2009 Le A, Zielinski R, He C, Crow MT, Biswal S, Tuder RM, Becker PM. Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema. American Journal of Respiratory and Critical Care Medicine. 180: 396-406. PMID 19520907 DOI: 10.1164/Rccm.200809-1483Oc  0.366
2009 Hassoun HT, Lie ML, Grigoryev DN, Liu M, Tuder RM, Rabb H. Kidney ischemia-reperfusion injury induces caspase-dependent pulmonary apoptosis. American Journal of Physiology. Renal Physiology. 297: F125-37. PMID 19403643 DOI: 10.1152/Ajprenal.90666.2008  0.476
2009 Rangasamy T, Misra V, Zhen L, Tankersley CG, Tuder RM, Biswal S. Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L888-900. PMID 19286929 DOI: 10.1152/Ajplung.90369.2008  0.428
2009 Asosingh K, Erzurum SC, Yoder MC, Tuder RM. Letter by asosingh et Al regarding article, "circulating endothelial progenitor cells in patients with eisenmenger syndrome and idiopathic pulmonary arterial hypertension". Circulation. 119: e230; author reply e. PMID 19273727 DOI: 10.1161/Circulationaha.108.800961  0.437
2009 Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA. Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 41: 553-61. PMID 19251945 DOI: 10.1165/Rcmb.2008-0271Oc  0.544
2009 Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 250-5. PMID 19104057 DOI: 10.1073/Pnas.0804333106  0.473
2009 Singh A, Ling G, Suhasini AN, Zhang P, Yamamoto M, Navas-Acien A, Cosgrove G, Tuder RM, Kensler TW, Watson WH, Biswal S. Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs. Free Radical Biology & Medicine. 46: 376-86. PMID 19027064 DOI: 10.1016/J.Freeradbiomed.2008.10.026  0.446
2009 Graham BB, Tuder RM. Pathogenesis of pulmonary hypertension National Medical Journal of China. 89: 2091-2093. DOI: 10.3760/Cma.J.Issn.0376-2491.2009.30.002  0.498
2008 Yun JH, Henson PM, Tuder RM. Phagocytic clearance of apoptotic cells: role in lung disease. Expert Review of Respiratory Medicine. 2: 753-65. PMID 20477237 DOI: 10.1586/17476348.2.6.753  0.459
2008 Franks TJ, Colby TV, Travis WD, Tuder RM, Reynolds HY, Brody AR, Cardoso WV, Crystal RG, Drake CJ, Engelhardt J, Frid M, Herzog E, Mason R, Phan SH, Randell SH, et al. Resident cellular components of the human lung: current knowledge and goals for research on cell phenotyping and function. Proceedings of the American Thoracic Society. 5: 763-6. PMID 18757314 DOI: 10.1513/pats.200803-025HR  0.324
2008 Alder JK, Chen JJ, Lancaster L, Danoff S, Su SC, Cogan JD, Vulto I, Xie M, Qi X, Tuder RM, Phillips JA, Lansdorp PM, Loyd JE, Armanios MY. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13051-6. PMID 18753630 DOI: 10.1073/Pnas.0804280105  0.383
2008 Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/Jbc.M804595200  0.489
2008 Le A, Damico R, Damarla M, Boueiz A, Pae HH, Skirball J, Hasan E, Peng X, Chesley A, Crow MT, Reddy SP, Tuder RM, Hassoun PM. Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 1282-90. PMID 18669934 DOI: 10.1152/Japplphysiol.90689.2008  0.339
2008 Tuder RM, Yun JH. It takes two to tango: Cigarette smoke partners with viruses to promote emphysema Journal of Clinical Investigation. 118: 2689-2693. PMID 18654673 DOI: 10.1172/Jci36536  0.394
2008 Malhotra D, Thimmulappa R, Navas-Acien A, Sandford A, Elliott M, Singh A, Chen L, Zhuang X, Hogg J, Pare P, Tuder RM, Biswal S. Expression of concern: Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. American Journal of Respiratory and Critical Care Medicine. 178: 592-604. PMID 18556627 DOI: 10.1164/Rccm.200803-380Oc  0.43
2008 Tuder RM, Yun JH. Vascular endothelial growth factor of the lung: friend or foe Current Opinion in Pharmacology. 8: 255-260. PMID 18468486 DOI: 10.1016/J.Coph.2008.03.003  0.413
2008 Petrache I, Diab K, Knox KS, Twigg HL, Stephens RS, Flores S, Tuder RM. HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism. Thorax. 63: 463-9. PMID 18443163 DOI: 10.1136/Thx.2007.079111  0.368
2008 Tuder RM, Yun JH, Graham BB. Cigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung American Journal of Respiratory Cell and Molecular Biology. 39: 1-6. PMID 18441278 DOI: 10.1165/Rcmb.2008-0117Tr  0.362
2008 Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, Berdyshev EV, Lungarella G, Tuder RM. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L44-53. PMID 18441093 DOI: 10.1152/Ajplung.00448.2007  0.412
2008 Grigoryev DN, Mathai SC, Fisher MR, Girgis RE, Zaiman AL, Housten-Harris T, Cheadle C, Gao L, Hummers LK, Champion HC, Garcia JG, Wigley FM, Tuder RM, Barnes KC, Hassoun PM. Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Translational Research : the Journal of Laboratory and Clinical Medicine. 151: 197-207. PMID 18355767 DOI: 10.1016/J.Trsl.2007.12.010  0.434
2008 Neptune ER, Podowski M, Calvi C, Cho JH, Garcia JG, Tuder R, Linnoila RI, Tsai MJ, Dietz HC. Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lung. The Journal of Biological Chemistry. 283: 21160-9. PMID 18339630 DOI: 10.1074/Jbc.M708692200  0.493
2008 Asosingh K, Aldred MA, Vasanji A, Drazba J, Sharp J, Farver C, Comhair SA, Xu W, Licina L, Huang L, Anand-Apte B, Yoder MC, Tuder RM, Erzurum SC. Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. The American Journal of Pathology. 172: 615-27. PMID 18258847 DOI: 10.2353/Ajpath.2008.070705  0.441
2008 Hoag JB, Liu M, Easley RB, Britos-Bray MF, Kesari P, Hassoun H, Haas M, Tuder RM, Rabb H, Simon BA. Effects of acid aspiration-induced acute lung injury on kidney function. American Journal of Physiology. Renal Physiology. 294: F900-8. PMID 18256314 DOI: 10.1152/Ajprenal.00357.2007  0.354
2008 Zaiman AL, Podowski M, Medicherla S, Gordy K, Xu F, Zhen L, Shimoda LA, Neptune E, Higgins L, Murphy A, Chakravarty S, Protter A, Sehgal PB, Champion HC, Tuder RM. Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 177: 896-905. PMID 18202349 DOI: 10.1164/Rccm.200707-1083Oc  0.457
2008 Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I. Apoptotic sphingolipid signaling by ceramides in lung endothelial cells. American Journal of Respiratory Cell and Molecular Biology. 38: 639-46. PMID 18192502 DOI: 10.1165/Rcmb.2007-0274Oc  0.41
2008 Henson PM, Tuder RM. Apoptosis in the lung: induction, clearance and detection. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L601-11. PMID 18178675 DOI: 10.1152/Ajplung.00320.2007  0.391
2008 Mukhopadhyay S, Shah M, Xu F, Patel K, Tuder RM, Sehgal PB. Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L449-68. PMID 18083767 DOI: 10.1152/Ajplung.00377.2007  0.506
2008 McGrath-Morrow S, Rangasamy T, Cho C, Sussan T, Neptune E, Wise R, Tuder RM, Biswal S. Impaired lung homeostasis in neonatal mice exposed to cigarette smoke. American Journal of Respiratory Cell and Molecular Biology. 38: 393-400. PMID 17975176 DOI: 10.1165/Rcmb.2007-0104Oc  0.43
2007 Tuder RM, Yun JH, Bhunia A, Fijalkowska I. Hypoxia and chronic lung disease. Journal of Molecular Medicine (Berlin, Germany). 85: 1317-24. PMID 18040654 DOI: 10.1007/S00109-007-0280-4  0.495
2007 Papaiahgari S, Yerrapureddy A, Reddy SR, Reddy NM, Dodd-O JM, Crow MT, Grigoryev DN, Barnes K, Tuder RM, Yamamoto M, Kensler TW, Biswal S, Mitzner W, Hassoun PM, Reddy SP. Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. American Journal of Respiratory and Critical Care Medicine. 176: 1222-35. PMID 17901416 DOI: 10.1164/Rccm.200701-060Oc  0.39
2007 Levine SM, Raben N, Xie D, Askin FB, Tuder R, Mullins M, Rosen A, Casciola-Rosen LA. Novel conformation of histidyl-transfer RNA synthetase in the lung: the target tissue in Jo-1 autoantibody-associated myositis. Arthritis and Rheumatism. 56: 2729-39. PMID 17665459 DOI: 10.1002/Art.22790  0.356
2007 Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiological Reviews. 87: 1047-82. PMID 17615396 DOI: 10.1152/Physrev.00048.2006  0.435
2007 Gao L, Flores C, Fan-Ma S, Miller EJ, Moitra J, Moreno L, Wadgaonkar R, Simon B, Brower R, Sevransky J, Tuder RM, Maloney JP, Moss M, Shanholtz C, Yates CR, et al. Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations. Translational Research : the Journal of Laboratory and Clinical Medicine. 150: 18-29. PMID 17585860 DOI: 10.1016/J.Trsl.2007.02.007  0.35
2007 Tuder RM, Petrache I. Molecular multitasking in the airspace: alpha1-antitrypsin takes on thrombin and plasmin. American Journal of Respiratory Cell and Molecular Biology. 37: 130-4. PMID 17541009 DOI: 10.1165/Rcmb.2007-0163Tr  0.454
2007 Tuder RM, Marecki JC, Richter A, Fijalkowska I, Flores S. Pathology of pulmonary hypertension. Clinics in Chest Medicine. 28: 23-42, vii. PMID 17338926 DOI: 10.1016/J.Ccm.2006.11.010  0.464
2007 Hassoun HT, Grigoryev DN, Lie ML, Liu M, Cheadle C, Tuder RM, Rabb H. Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy. American Journal of Physiology. Renal Physiology. 293: F30-40. PMID 17327501 DOI: 10.1152/Ajprenal.00023.2007  0.411
2007 Girgis RE, Mozammel S, Champion HC, Li D, Peng X, Shimoda L, Tuder RM, Johns RA, Hassoun PM. Regression of chronic hypoxic pulmonary hypertension by simvastatin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1105-10. PMID 17277047 DOI: 10.1152/Ajplung.00411.2006  0.444
2007 Nathan SD, Noble PW, Tuder RM. Idiopathic pulmonary fibrosis and pulmonary hypertension: connecting the dots. American Journal of Respiratory and Critical Care Medicine. 175: 875-80. PMID 17255562 DOI: 10.1164/Rccm.200608-1153Cc  0.507
2007 Xu W, Koeck T, Lara AR, Neumann D, DiFilippo FP, Koo M, Janocha AJ, Masri FA, Arroliga AC, Jennings C, Dweik RA, Tuder RM, Stuehr DJ, Erzurum SC. Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 1342-7. PMID 17227868 DOI: 10.1073/Pnas.0605080104  0.467
2007 Hassoun HT, Lie M, Grigoryev DN, Liu M, Tuder RM, Rabb H. 122: Ischemic acute kidney injury (AKI) induces pulmonary apoptosis: Potential mechanism underlying AKI-associated lung dysfunction Journal of Surgical Research. 137: 203. DOI: 10.1016/J.Jss.2006.12.135  0.427
2007 Hassoun H, Lie M, Grigoryev D, Liu M, Tuder R, Rabb H. Ischemic acute kidney injury (AKI) induces caspase-dependent pulmonary endothelial apoptosis which contributes to AKI-associated lung injury Journal of the American College of Surgeons. 205. DOI: 10.1016/J.Jamcollsurg.2007.06.058  0.404
2006 Taraseviciene-Stewart L, Douglas IS, Nana-Sinkam PS, Lee JD, Tuder RM, Nicolls MR, Voelkel NF. Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease? Proceedings of the American Thoracic Society. 3: 687-90. PMID 17065374 DOI: 10.1513/pats.200605-105SF  0.347
2006 Tuder RM, Yoshida T, Fijalkowka I, Biswal S, Petrache I. Role of lung maintenance program in the heterogeneity of lung destruction in emphysema. Proceedings of the American Thoracic Society. 3: 673-9. PMID 17065372 DOI: 10.1513/pats.200605-124SF  0.315
2006 Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM. alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis. The American Journal of Pathology. 169: 1155-66. PMID 17003475 DOI: 10.2353/Ajpath.2006.060058  0.421
2006 Petrache I, Natarajan V, Zhen L, Medler TR, Richter A, Berdyshev EV, Tuder RM. Ceramide causes pulmonary cell apoptosis and emphysema: a role for sphingolipid homeostasis in the maintenance of alveolar cells. Proceedings of the American Thoracic Society. 3: 510. PMID 16921130 DOI: 10.1513/pats.200603-071MS  0.341
2006 Tuder RM. [Pulmonary hypertension: characterization based on the experience of reference centers. ]. Revista Da Associacao Medica Brasileira (1992). 52: 127-9. PMID 16847512 DOI: 10.1590/s0104-42302006000300003  0.351
2006 Simon BA, Easley RB, Grigoryev DN, Ma SF, Ye SQ, Lavoie T, Tuder RM, Garcia JG. Microarray analysis of regional cellular responses to local mechanical stress in acute lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L851-61. PMID 16782753 DOI: 10.1152/Ajplung.00463.2005  0.39
2006 Marecki JC, Cool CD, Parr JE, Beckey VE, Luciw PA, Tarantal AF, Carville A, Shannon RP, Cota-Gomez A, Tuder RM, Voelkel NF, Flores SC. HIV-1 Nef is associated with complex pulmonary vascular lesions in SHIV-nef-infected macaques. American Journal of Respiratory and Critical Care Medicine. 174: 437-45. PMID 16728715 DOI: 10.1164/Rccm.200601-005Oc  0.398
2006 Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Cool C, Wood K, Tuder RM, Burns N, Kasper M, Voelkel NF. Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L668-76. PMID 16698853 DOI: 10.1152/Ajplung.00491.2005  0.494
2006 Abdulnour RE, Peng X, Finigan JH, Han EJ, Hasan EJ, Birukov KG, Reddy SP, Watkins JE, Kayyali US, Garcia JG, Tuder RM, Hassoun PM. Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L345-53. PMID 16632522 DOI: 10.1152/Ajplung.00453.2005  0.41
2006 McGrath-Morrow S, Cho C, Molls R, Burne-Taney M, Haas M, Hicklin DJ, Tuder R, Rabb H. VEGF receptor 2 blockade leads to renal cyst formation in mice. Kidney International. 69: 1741-8. PMID 16572116 DOI: 10.1038/Sj.Ki.5000314  0.317
2006 Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, Cruz P, Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Shapiro L, Zhang B, Song S, Hicklin D, Voelkel NF, Flotte T, ... Tuder RM, et al. A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema. American Journal of Respiratory and Critical Care Medicine. 173: 1222-8. PMID 16514110 DOI: 10.1164/Rccm.200512-1842Oc  0.416
2006 Voelkel NF, Vandivier RW, Tuder RM. Vascular endothelial growth factor in the lung American Journal of Physiology - Lung Cellular and Molecular Physiology. 290. PMID 16403941 DOI: 10.1152/Ajplung.00185.2005  0.482
2005 Girgis RE, Ma SF, Ye S, Grigoryev DN, Li D, Hassoun PM, Tuder RM, Johns RA, Garcia JG. Differential gene expression in chronic hypoxic pulmonary hypertension: effect of simvastatin treatment. Chest. 128: 579S. PMID 16373842 DOI: 10.1378/Chest.128.6_Suppl.579S  0.447
2005 West J, Tada Y, Fagan KA, Steudel W, Fouty BW, Harral JW, Miller M, Ozimek J, Tuder RM, Rodman DM. Suppression of type II bone morphogenic protein receptor in vascular smooth muscle induces pulmonary arterial hypertension in transgenic mice. Chest. 128: 553S. PMID 16373822 DOI: 10.1378/Chest.128.6_Suppl.553S  0.408
2005 Zaiman A, Fijalkowska I, Hassoun PM, Tuder RM. One hundred years of research in the pathogenesis of pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 33: 425-31. PMID 16234331 DOI: 10.1165/Rcmb.F307  0.471
2005 Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, Yamamoto M, Kensler TW, Tuder RM, Georas SN, Biswal S. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. The Journal of Experimental Medicine. 202: 47-59. PMID 15998787 DOI: 10.1084/Jem.20050538  0.334
2005 Peng X, Abdulnour RE, Sammani S, Ma SF, Han EJ, Hasan EJ, Tuder R, Garcia JG, Hassoun PM. Inducible nitric oxide synthase contributes to ventilator-induced lung injury. American Journal of Respiratory and Critical Care Medicine. 172: 470-9. PMID 15937288 DOI: 10.1164/Rccm.200411-1547Oc  0.396
2005 Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nature Medicine. 11: 491-8. PMID 15852018 DOI: 10.1038/Nm1238  0.449
2005 McGrath-Morrow SA, Cho C, Cho C, Zhen L, Hicklin DJ, Tuder RM. Vascular endothelial growth factor receptor 2 blockade disrupts postnatal lung development. American Journal of Respiratory Cell and Molecular Biology. 32: 420-7. PMID 15722510 DOI: 10.1165/Rcmb.2004-0287Oc  0.424
2005 Jacobson JR, Barnard JW, Grigoryev DN, Ma SF, Tuder RM, Garcia JG. Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L1026-32. PMID 15665042 DOI: 10.1152/Ajplung.00354.2004  0.419
2005 Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, Easley RB, McVerry BJ, Tuder RM, Standiford T, Brower RG, Barnes KC, Garcia JG. Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. American Journal of Respiratory and Critical Care Medicine. 171: 361-70. PMID 15579727 DOI: 10.1164/Rccm.200404-563Oc  0.387
2005 Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Moore M, Sullivan A, Nicolls MR, Fontenot AP, Tuder RM, Voelkel NF. An animal model of autoimmune emphysema. American Journal of Respiratory and Critical Care Medicine. 171: 734-42. PMID 15563631 DOI: 10.1164/Rccm.200409-1275Oc  0.349
2005 Tuder RM, Voelkel NF, Fagan KA. Cellular and Molecular Mechanisms of Pulmonary Hypertension Beyond Vasodilators Chest. 128: 1E-2E. DOI: 10.1378/Chest.128.6_Suppl.E1S  0.465
2004 Demura Y, Taraseviciene-Stewart L, Scerbavicius R, Tuder RM, Voelkel NF. N-acetylcysteine treatment protects against VEGF-receptor blockade-related emphysema. Copd. 1: 25-32. PMID 16997736 DOI: 10.1081/Copd-120030412  0.417
2004 Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. The Journal of Clinical Investigation. 114: 1248-59. PMID 15520857 DOI: 10.1172/Jci21146  0.423
2004 Richter A, Yeager ME, Zaiman A, Cool CD, Voelkel NF, Tuder RM. Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 170: 1340-8. PMID 15361368 DOI: 10.1164/Rccm.200311-1602Oc  0.771
2004 Golpon HA, Coldren CD, Zamora MR, Cosgrove GP, Moore MD, Tuder RM, Geraci MW, Voelkel NF. Emphysema lung tissue gene expression profiling American Journal of Respiratory Cell and Molecular Biology. 31: 595-600. PMID 15284076 DOI: 10.1165/Rcmb.2004-0008Oc  0.429
2004 Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, McGoon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, ... Tuder RM, et al. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 109: 2947-52. PMID 15210611 DOI: 10.1161/01.Cir.0000132476.87231.6F  0.494
2004 Pietra GG, Capron F, Stewart S, Leone O, Humbert M, Robbins IM, Reid LM, Tuder RM. Pathologic assessment of vasculopathies in pulmonary hypertension. Journal of the American College of Cardiology. 43: 25S-32S. PMID 15194175 DOI: 10.1016/J.Jacc.2004.02.033  0.515
2004 Vourlekis JS, Schwarz MI, Cherniack RM, Curran-Everett D, Cool CD, Tuder RM, King TE, Brown KK. The effect of pulmonary fibrosis on survival in patients with hypersensitivity pneumonitis American Journal of Medicine. 116: 662-668. PMID 15121492 DOI: 10.1016/J.Amjmed.2003.12.030  0.421
2004 Tuder RM, McGrath S, Voelkel NF, Geraci MW. Oxygen-Dependent Regulation of Pulmonary Circulation Methods in Enzymology. 381: 87-106. PMID 15063667 DOI: 10.1016/S0076-6879(04)81005-X  0.507
2004 West J, Fagan K, Steudel W, Fouty B, Lane K, Harral J, Hoedt-Miller M, Tada Y, Ozimek J, Tuder R, Rodman DM. Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circulation Research. 94: 1109-14. PMID 15031260 DOI: 10.1161/01.Res.0000126047.82846.20  0.445
2004 Peng X, Hassoun PM, Sammani S, McVerry BJ, Burne MJ, Rabb H, Pearse D, Tuder RM, Garcia JG. Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. American Journal of Respiratory and Critical Care Medicine. 169: 1245-51. PMID 15020292 DOI: 10.1164/Rccm.200309-1258Oc  0.406
2004 Budhiraja R, Tuder RM, Hassoun PM. Endothelial dysfunction in pulmonary hypertension. Circulation. 109: 159-65. PMID 14734504 DOI: 10.1161/01.Cir.0000102381.57477.50  0.536
2004 Jones JE, Walker JL, Song Y, Weiss N, Cardoso WV, Tuder RM, Loscalzo J, Zhang YY. Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1775-84. PMID 14726295 DOI: 10.1152/Ajpheart.00281.2003  0.503
2004 Bowers R, Cool C, Murphy RC, Tuder RM, Hopken MW, Flores SC, Voelkel NF. Oxidative stress in severe pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 169: 764-9. PMID 14701708 DOI: 10.1164/Rccm.200301-147Oc  0.452
2004 McGrath-Morrow SA, Cho C, Soutiere S, Mitzner W, Tuder R. The effect of neonatal hyperoxia on the lung of p21Waf1/Cip1/Sdi1-deficient mice. American Journal of Respiratory Cell and Molecular Biology. 30: 635-40. PMID 14607813 DOI: 10.1165/Rcmb.2003-0049Oc  0.382
2004 Voelkel NF, Taraseviciene-Stewart L, Tuder R. Emphysema - A vascular disease? Drug Discovery Today: Disease Mechanisms. 1: 145-149. DOI: 10.1016/J.Ddmec.2004.08.010  0.463
2003 Bull TM, Golpon H, Hebbel RP, Solovey A, Cool CD, Tuder RM, Geraci MW, Voelkel NF. Circulating endothelial cells in pulmonary hypertension. Thrombosis and Haemostasis. 90: 698-703. PMID 14515191 DOI: 10.1160/Th03-04-0251  0.537
2003 Cool CD, Rai PR, Yeager ME, Hernandez-Saavedra D, Serls AE, Bull TM, Geraci MW, Brown KK, Routes JM, Tuder RM, Voelkel NF. Expression of human herpesvirus 8 in primary pulmonary hypertension. The New England Journal of Medicine. 349: 1113-22. PMID 13679525 DOI: 10.1056/Nejmoa035115  0.74
2003 Girgis RE, Li D, Zhan X, Garcia JG, Tuder RM, Hassoun PM, Johns RA. Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. American Journal of Physiology. Heart and Circulatory Physiology. 285: H938-45. PMID 12750068 DOI: 10.1152/Ajpheart.01097.2002  0.487
2003 Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. American Journal of Respiratory Cell and Molecular Biology. 28: 551-4. PMID 12707010 DOI: 10.1165/Rcmb.F269  0.331
2003 Tuder RM, McGrath S, Neptune E. The pathobiological mechanisms of emphysema models: what do they have in common? Pulmonary Pharmacology & Therapeutics. 16: 67-78. PMID 12670776 DOI: 10.1016/S1094-5539(02)00099-8  0.379
2003 Tuder RM, Zhen L, Cho CY, Taraseviciene-Stewart L, Kasahara Y, Salvemini D, Voelkel NF, Flores SC. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. American Journal of Respiratory Cell and Molecular Biology. 29: 88-97. PMID 12600822 DOI: 10.1165/Rcmb.2002-0228Oc  0.414
2003 Gerhardt SG, Tuder RM, Girgis RE, Yang SC, Conte JV, Orens JB. Pulmonary eosinophilia following lung transplantation for sarcoidosis in two patients. Chest. 123: 629-32. PMID 12576393 DOI: 10.1378/Chest.123.2.629  0.491
2003 Choe KH, Taraseviciene-Stewart L, Scerbavicius R, Gera L, Tuder RM, Voelkel NF. Methylprednisolone causes matrix metalloproteinase-dependent emphysema in adult rats. American Journal of Respiratory and Critical Care Medicine. 167: 1516-21. PMID 12522028 DOI: 10.1164/Rccm.200210-1207Oc  0.405
2003 Hoshikawa Y, Nana-Sinkam P, Moore MD, Sotto-Santiago S, Phang T, Keith RL, Morris KG, Kondo T, Tuder RM, Voelkel NF, Geraci MW. Hypoxia induces different genes in the lungs of rats compared with mice. Physiological Genomics. 12: 209-19. PMID 12464684 DOI: 10.1152/Physiolgenomics.00081.2001  0.463
2003 Jones J, Walker J, Song Y, Cardoso W, Tuder R, Hayes A, Weiss N, Loscalzo J, Zhang Y. Effects of overexpression and inhibition of 5-lipoxygenase o on the development of pulmonary hypertension in a rat model Journal of the American College of Cardiology. 41: 223. DOI: 10.1016/S0735-1097(03)81620-0  0.393
2002 Tuder RM, Voelkel NF. Angiogenesis and pulmonary hypertension: A unique process in a unique disease Antioxidants and Redox Signaling. 4: 833-843. PMID 12470512 DOI: 10.1089/152308602760598990  0.542
2002 Le Cras TD, Markham NE, Tuder RM, Voelkel NF, Abman SH. Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure American Journal of Physiology - Lung Cellular and Molecular Physiology. 283: L555-L562. PMID 12169575 DOI: 10.1152/Ajplung.00408.2001  0.492
2002 Taraseviciene-Stewart L, Gera L, Hirth P, Voelkel NF, Tuder RM, Stewart JM. A bradykinin antagonist and a caspase inhibitor prevent severe pulmonary hypertension in a rat model. Canadian Journal of Physiology and Pharmacology. 80: 269-74. PMID 12025960 DOI: 10.1139/Y02-047  0.447
2002 Voelkel NF, Cool C, Taraceviene-Stewart L, Geraci MW, Yeager M, Bull T, Kasper M, Tuder RM. Janus face of vascular endothelial growth factor: the obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Critical Care Medicine. 30: S251-6. PMID 12004244 DOI: 10.1097/00003246-200205001-00013  0.768
2002 Vourlekis JS, Schwarz MI, Cool CD, Tuder RM, King TE, Brown KK. Nonspecific interstitial pneumonitis as the sole histologic expression of hypersensitivity pneumonitis American Journal of Medicine. 112: 490-493. PMID 11959061 DOI: 10.1016/S0002-9343(02)01046-X  0.3
2002 Geraci MW, Hoshikawa Y, Yeager M, Golpon H, Gesell T, Tuder RM, Voelkel NF. Gene expression profiles in pulmonary hypertension. Chest. 121: 104S-105S. PMID 11893725 DOI: 10.1378/Chest.121.3_Suppl.104S  0.739
2002 Yeager ME, Golpon HA, Voelkel NF, Tuder RM. Microsatellite mutational analysis of endothelial cells within plexiform lesions from patients with familial, pediatric, and sporadic pulmonary hypertension. Chest. 121: 61S. PMID 11893687 DOI: 10.1378/Chest.121.3_Suppl.61S  0.726
2002 Markopoulo KD, Cool CD, Elliot TL, Lync DA, Newell JD, Hale VA, Brown KK, Schwarz MI, Tuder RM. Obliterative bronchiolitis: varying presentations and clinicopathological correlation. The European Respiratory Journal. 19: 20-30. PMID 11843321 DOI: 10.1183/09031936.02.00282001  0.391
2002 Tuder RM, Zaiman AL. Prostacyclin analogs as the brakes for pulmonary artery smooth muscle cell proliferation: is it sufficient to treat severe pulmonary hypertension? American Journal of Respiratory Cell and Molecular Biology. 26: 171-4. PMID 11804866 DOI: 10.1165/Ajrcmb.26.2.F230  0.57
2002 Park JS, Brown KK, Tuder RM, Hale VA, King Jr TE, Lynch DA. Respiratory bronchiolitis-associated interstitial lung disease: radiologic features with clinical and pathologic correlation. Journal of Computer Assisted Tomography. 26: 13-20. PMID 11801899 DOI: 10.1097/00004728-200201000-00003  0.384
2002 Lee JH, Chun YG, Lee IC, Tuder RM, Hong SB, Shim TS, Lim CM, Koh Y, Kim WS, Kim DS, Kim WD, Lee SD. Pathogenic role of endothelin 1 in hemodynamic dysfunction in experimental acute pulmonary thromboembolism. American Journal of Respiratory and Critical Care Medicine. 164: 1282-7. PMID 11673223 DOI: 10.1164/Ajrccm.164.7.2011011  0.422
2002 Tuder RM, Cool CD, Yeager M, Taraseviciene-Stewart L, Bull TM, Voelkel NF. The pathobiology of pulmonary hypertension. Endothelium. Clinics in Chest Medicine. 22: 405-18. PMID 11590837 DOI: 10.1016/S0272-5231(05)70280-X  0.771
2002 Girgis RE, Li D, Tuder RM, Johns RA, Garcia JGN. Attenuation of hypoxic pulmonary hypertension in rats by the HMG-CoA reductase inhibitor, simvastatin Journal of Heart and Lung Transplantation. 21: 149. DOI: 10.1016/S1053-2498(01)00695-7  0.468
2001 Geraci MW, Gao B, Hoshikawa Y, Yeager ME, Tuder RM, Voelkel NF. Genomic approaches to research in pulmonary hypertension. Respiratory Research. 2: 210-5. PMID 11686886 DOI: 10.1186/Rr59  0.703
2001 Tuder RM, Chacon M, Alger L, Wang J, Taraseviciene-Stewart L, Kasahara Y, Cool CD, Bishop AE, Geraci M, Semenza GL, Yacoub M, Polak JM, Voelkel NF. Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis. The Journal of Pathology. 195: 367-74. PMID 11673836 DOI: 10.1002/Path.953  0.476
2001 Stevens T, Rosenberg R, Aird W, Quertermous T, Johnson FL, Garcia JG, Hebbel RP, Tuder RM, Garfinkel S. NHLBI workshop report: endothelial cell phenotypes in heart, lung, and blood diseases. American Journal of Physiology. Cell Physiology. 281: C1422-33. PMID 11600404 DOI: 10.1152/Ajpcell.2001.281.5.C1422  0.424
2001 Tuder RM, Yeager ME, Geraci M, Golpon HA, Voelkel NF. Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene. The European Respiratory Journal. 17: 1065-9. PMID 11491145 DOI: 10.1183/09031936.01.00202701  0.773
2001 Tuder RM, Voelkel NF. Plexiform lesion in severe pulmonary hypertension: association with glomeruloid lesion American Journal of Pathology. 159: 382-383. PMID 11438486 DOI: 10.1016/S0002-9440(10)61705-1  0.377
2001 Geraci MW, Moore M, Gesell T, Yeager ME, Alger L, Golpon H, Gao B, Loyd JE, Tuder RM, Voelkel NF. Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis. Circulation Research. 88: 555-62. PMID 11282888 DOI: 10.1161/01.Res.88.6.555  0.751
2001 Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. American Journal of Respiratory and Critical Care Medicine. 163: 737-44. PMID 11254533 DOI: 10.1164/Ajrccm.163.3.2002117  0.472
2001 Golpon HA, Geraci MW, Moore MD, Miller HL, Miller GJ, Tuder RM, Voelkel NF. HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema. The American Journal of Pathology. 158: 955-66. PMID 11238043 DOI: 10.1016/S0002-9440(10)64042-4  0.481
2001 Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 427-38. PMID 11156958 DOI: 10.1096/Fj.00-0343Com  0.552
2001 Yeager ME, Halley GR, Golpon HA, Voelkel NF, Tuder RM. Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension. Circulation Research. 88: E2-E11. PMID 11139485 DOI: 10.1161/01.Res.88.1.E2  0.716
2001 Lee SD, Lee DS, Chun YG, Paik SH, Kim WS, Kim DS, Kim WD, Tuder RM, Voelkel NF. Transforming growth factor-beta1 induces endothelin-1 in a bovine pulmonary artery endothelial cell line and rat lungs via cAMP. Pulmonary Pharmacology & Therapeutics. 13: 257-65. PMID 11061980 DOI: 10.1006/Pupt.2000.0252  0.337
2000 Kasahara Y, Tuder RM, Taraseviciene-Stewart L, Le Cras TD, Abman S, Hirth PK, Waltenberger J, Voelkel NF. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema Journal of Clinical Investigation. 106: 1311-1319. PMID 11104784 DOI: 10.1172/Jci10259  0.494
2000 Voelkel NF, Tuder RM. Hypoxia-induced pulmonary vascular remodeling: A model for what human disease? Journal of Clinical Investigation. 106: 733-738. PMID 10995781 DOI: 10.1172/Jci11144  0.508
2000 Jakkula M, Le Cras TD, Gebb S, Hirth KP, Tuder RM, Voelkel NF, Abman SH. Inhibition of angiogenesis decreases alveolarization in the developing rat lung American Journal of Physiology - Lung Cellular and Molecular Physiology. 279: L600-L607. PMID 10956636 DOI: 10.1152/Ajplung.2000.279.3.L600  0.47
2000 Tuder RM, Wood K, Taraseviciene L, Flores SC, Voekel NF. Cigarette smoke extract decreases the expression of vascular endothelial growth factor by cultured cells and triggers apoptosis of pulmonary endothelial cells Chest. 117: 241S-2S. PMID 10843927 DOI: 10.1378/Chest.117.5_Suppl_1.241S  0.409
2000 Kasahara Y, Tuder RM, Cool CD, Voelkel NF. Expression of 15-lipoxygenase and evidence for apoptosis in the lungs from patients with COPD Chest. 117. DOI: 10.1378/Chest.117.5_Suppl_1.260S  0.436
2000 Tuder RM, Kasahara Y, Voelkel NF. Inhibition of vascular endothelial growth factor receptors causes emphysema in rats Chest. 117. DOI: 10.1016/S0012-3692(15)51033-7  0.324
1999 le Cras TD, Kim DH, Gebb S, Markham NE, Shannon JM, Tuder RM, Abman SH. Abnormal lung growth and the development of pulmonary hypertension in the Fawn-Hooded rat. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L709-L718. PMID 29592132 DOI: 10.1152/ajplung.1999.277.4.L709  0.409
1999 Voelkel NF, Tuder RM. Severe pulmonary hypertensive diseases: A perspective European Respiratory Journal. 14: 1246-1250. PMID 10624750 DOI: 10.1183/09031936.99.14612469  0.477
1999 Le Cras TD, Kim DH, Gebb S, Markham NE, Shannon JM, Tuder RM, Abman SH. Abnormal lung growth and the development of pulmonary hypertension in the Fawn-Hooded rat American Journal of Physiology - Lung Cellular and Molecular Physiology. 277: L709-L718. PMID 10516211 DOI: 10.1152/Ajplung.1999.277.4.L709  0.505
1999 Cool CD, Stewart JS, Werahera P, Miller GJ, Williams RL, Voelkel NF, Tuder RM. Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth. The American Journal of Pathology. 155: 411-9. PMID 10433934 DOI: 10.1016/S0002-9440(10)65137-1  0.471
1999 Geraci MW, Gao B, Shepherd DC, Moore MD, Westcott JY, Fagan KA, Alger LA, Tuder RM, Voelkel NF. Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension. The Journal of Clinical Investigation. 103: 1509-15. PMID 10359560 DOI: 10.1172/Jci5911  0.495
1999 Tuder RM, Cool CD, Geraci MW, Wang J, Abman SH, Wright L, Badesch D, Voelkel NF. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension American Journal of Respiratory and Critical Care Medicine. 159: 1925-1932. PMID 10351941 DOI: 10.1164/Ajrccm.159.6.9804054  0.51
1999 Tuder RM, Radisavljevic Z, Shroyer KR, Polak JM, Voelkel NF. Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 158: 1999-2001. PMID 9847298 DOI: 10.1164/Ajrccm.158.6.9805002  0.478
1998 Donnelly TJ, Tuder RM, Vendegna TR. A 48-year-old woman with peripheral neuropathy, hypercalcemia, and pulmonary infiltrates. Chest. 114: 1205-9. PMID 9792597 DOI: 10.1378/Chest.114.4.1205  0.393
1998 Nicolls MR, Terada LS, Tuder RM, Prindiville SA, Schwarz MI. Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome. American Journal of Respiratory and Critical Care Medicine. 158: 1302-5. PMID 9769296 DOI: 10.1164/Ajrccm.158.4.9709085  0.416
1998 Voelkel NF, Cool C, Lee SD, Wright L, Geraci MW, Tuder RM. Primary pulmonary hypertension between inflammation and cancer. Chest. 114: 225S-230S. PMID 9741573 DOI: 10.1378/Chest.114.3_Supplement.225S  0.512
1998 Guldemeester HA, Stenmark KR, Brough G, Tuder RM, Stevens T. Role of adenylyl cyclase in proliferation of neonatal pulmonary artery smooth muscle cells. Chest. 114: 38S-39S. PMID 9676620 DOI: 10.1378/Chest.114.1_Supplement.38S  0.406
1998 Cohen AJ, Cool C, Gorg S, Gilman LB, Tuder RM, Miller YE, Voelkel NF. Low or absent peptidase expression in plexiform lesions of primary pulmonary hypertension. Chest. 114: 30S-31S. PMID 9676613 DOI: 10.1378/Chest.114.1_Supplement.30S  0.443
1998 Tuder RM, Lee S, Cool CC. Histopathology of Pulmonary Hypertension Chest. 114. PMID 9676599 DOI: 10.1378/Chest.114.1_Supplement.1S-A  0.492
1998 Tuder RM, Voelkel NF. Pulmonary hypertension and inflammation Journal of Laboratory and Clinical Medicine. 132: 16-24. PMID 9665367 DOI: 10.1016/S0022-2143(98)90020-8  0.498
1998 Schwarz MI, Zamora MR, Hodges TN, Chan ED, Bowler RP, Tuder RM. Isolated pulmonary capillaritis and diffuse alveolar hemorrhage in rheumatoid arthritis and mixed connective tissue disease. Chest. 113: 1609-15. PMID 9631801 DOI: 10.1378/Chest.113.6.1609  0.379
1998 Silliman CC, Voelkel NF, Allard JD, Elzi DJ, Tuder RM, Johnson JL, Ambruso DR. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. The Journal of Clinical Investigation. 101: 1458-67. PMID 9525989 DOI: 10.1172/Jci1841  0.37
1998 Lee SD, Shroyer KR, Markham NE, Cool CD, Voelkel NF, Tuder RM. Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. The Journal of Clinical Investigation. 101: 927-34. PMID 9486960 DOI: 10.1172/Jci1910  0.479
1998 Le Cras TD, Tyler RC, Horan MP, Morris KG, Tuder RM, McMurtry IF, Johns RA, Abman SH. Effects of chronic hypoxia and altered hemodynamics on endothelial nitric oxide synthase expression in the adult rat lung Journal of Clinical Investigation. 101: 795-801. PMID 9466974 DOI: 10.1172/Jci786  0.491
1998 Wright L, Tuder RM, Wang J, Cool CD, Lepley RA, Voelkel NF. 5-Lipoxygenase and 5-lipoxygenase activating protein (FLAP) immunoreactivity in lungs from patients with primary pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 157: 219-29. PMID 9445303 DOI: 10.1164/Ajrccm.157.1.9704003  0.526
1998 Höper MM, Voelkel NF, Bates TO, Allard JD, Horan M, Shepherd D, Tuder RM. Prostaglandins induce vascular endothelial growth factor in a human monocytic cell line and rat lungs via cAMP. American Journal of Respiratory Cell and Molecular Biology. 17: 748-56. PMID 9409562 DOI: 10.1165/Ajrcmb.17.6.2888  0.412
1998 Kim DH, Le Cras TD, Horan MP, Tuder RM, Abman SH. Impaired Developmental Expression of Lung Endothelial Nitric Oxide Synthase and Abnormal Alveolarization in the Fawn-Hooded Rat : Implications for the Risk of Developing Pulmonary Hypertension 1689 Pediatric Research. 43: 288-288. DOI: 10.1203/00006450-199804001-01711  0.481
1997 Voelkel NF, Tuder RM. Cellular and molecular biology of vascular smooth muscle cells in pulmonary hypertension Pulmonary Pharmacology and Therapeutics. 10: 231-241. PMID 9778486 DOI: 10.1006/Pupt.1998.0100  0.445
1997 Zamora MR, Warner ML, Tuder R, Schwarz MI. Diffuse alveolar hemorrhage and systemic lupus erythematosus. Clinical presentation, histology, survival, and outcome. Medicine. 76: 192-202. PMID 9193454 DOI: 10.1097/00005792-199705000-00005  0.341
1997 Villamor E, Le Cras TD, Horan MP, Halbower AC, Tuder RM, Abman SH. Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus. The American Journal of Physiology. 272: L1013-20. PMID 9176268 DOI: 10.1152/Ajplung.1997.272.5.L1013  0.535
1997 Tajchman UW, Tuder RM, Horan M, Parker TA, Abman SH. Persistent eNOS in lung hypoplasia caused by left pulmonary artery ligation in the ovine fetus. The American Journal of Physiology. 272: L969-78. PMID 9176263 DOI: 10.1152/Ajplung.1997.272.5.L969  0.519
1997 Jennings CA, King TE, Tuder R, Cherniack RM, Schwarz MI. Diffuse alveolar hemorrhage with underlying isolated, pauciimmune pulmonary capillaritis. American Journal of Respiratory and Critical Care Medicine. 155: 1101-1109. PMID 9116994 DOI: 10.1164/Ajrccm.155.3.9116994  0.435
1997 Cool CD, Kennedy D, Voelkel NF, Tuder RM. Pathogenesis and evolution of plexiform lesions in pulmonary hypertension associated with scleroderma and human immunodeficiency virus infection Human Pathology. 28: 434-442. PMID 9104943 DOI: 10.1016/S0046-8177(97)90032-0  0.403
1997 Ivy DD, Parker TA, Ziegler JW, Galan HL, Kinsella JP, Tuder RM, Abman SH. Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus. The Journal of Clinical Investigation. 99: 1179-86. PMID 9077525 DOI: 10.1172/Jci119274  0.46
1996 Tuder RM. A pathologist's approach to interstitial lung disease Current Opinion in Pulmonary Medicine. 2: 357-363. PMID 9363168 DOI: 10.1097/00063198-199609000-00003  0.443
1996 Garg K, Zamora MR, Tuder R, Armstrong JD, Lynch DA. Lung Transplantation: Indications, Donor and Recipient Selection, and Imaging of Complications Radiographics. 16: 355-367. PMID 8966293 DOI: 10.1148/Radiographics.16.2.8966293  0.384
1996 Voelkel NF, Hoeper M, Maloney J, Tuder RM. Vascular endothelial growth factor in pulmonary hypertension Annals of the New York Academy of Sciences. 796: 186-193. PMID 8906225 DOI: 10.1111/J.1749-6632.1996.Tb32580.X  0.481
1996 Fitzgerald JE, King TE, Lynch DA, Tuder RM, Schwarz MI. Diffuse panbronchiolitis in the United States American Journal of Respiratory and Critical Care Medicine. 154: 497-503. PMID 8756828 DOI: 10.1164/Ajrccm.154.2.8756828  0.422
1996 Voelkel NF, Tuder RM, Wade K, Höper M, Lepley RA, Goulet JL, Koller BH, Fitzpatrick F. Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats. The Journal of Clinical Investigation. 97: 2491-8. PMID 8647941 DOI: 10.1172/Jci118696  0.549
1996 Nick J, Tuder R, May R, Fisher J. Polyarteritis nodosa with pulmonary vasculitis. American Journal of Respiratory and Critical Care Medicine. 153: 450-3. PMID 8542157 DOI: 10.1164/Ajrccm.153.1.8542157  0.478
1996 Crausman RS, Jennings CA, Tuder RM, Ackerson LM, Irvin CG, King TE. Pulmonary histiocytosis X: pulmonary function and exercise pathophysiology. American Journal of Respiratory and Critical Care Medicine. 153: 426-35. PMID 8542154 DOI: 10.1164/Ajrccm.153.1.8542154  0.382
1996 Villamor E, Horan M, Tuder RM, Halbower AC, Abman SH. CHRONIC INTRAUTERINE PULMONARY HYPERTENSION IMPAIRS NORMAL DEVELOPMENT OF ENDOTHELIAL NITRIC OXIDE SYNTHASE PROTEIN AND ACTIVITY IN THE OVINE FETUS.• 2108 Pediatric Research. 39: 354-354. DOI: 10.1203/00006450-199604001-02132  0.487
1996 Taichman U, Horan M, Tuder R, Abman SH. PERSISTENT ENDOTHELIAL NITRIC OXIDE SYNTHASE CONTENT IN LUNG HYPOPLASIA DUE TO LEFT PULMONARY ARTERY LIGATION IN THE OVINE FETUS. † 2093 Pediatric Research. 39: 351-351. DOI: 10.1203/00006450-199604001-02117  0.491
1995 Voelkel NF, Tuder RM. Cellular and molecular mechanisms in the pathogenesis of severe pulmonary hypertension European Respiratory Journal. 8: 2129-2138. PMID 8666110 DOI: 10.1183/09031936.95.08122129  0.552
1995 Abraham E, Bursten S, Shenkar R, Allbee J, Tuder R, Woodson P, Guidot DM, Rice G, Singer JW, Repine JE. Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice. The Journal of Experimental Medicine. 181: 569-75. PMID 7836912 DOI: 10.1084/Jem.181.2.569  0.418
1995 Schwarz MI, Sutarik JM, Nick JA, Leff JA, Emlen JW, Tuder RM. Pulmonary capillaritis and diffuse alveolar hemorrhage. A primary manifestation of polymyositis. American Journal of Respiratory and Critical Care Medicine. 151: 2037-40. PMID 7767555 DOI: 10.1164/Ajrccm.151.6.7767555  0.411
1995 Tuder RM, Flook BE, Voelkel NF. Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia: Modulation of gene expression by nitric oxide Journal of Clinical Investigation. 95: 1798-1807. PMID 7706486 DOI: 10.1172/Jci117858  0.458
1995 Abraham E, Jesmok G, Tuder R, Allbee J, Chang YH. Contribution of tumor necrosis factor-alpha to pulmonary cytokine expression and lung injury after hemorrhage and resuscitation. Critical Care Medicine. 23: 1319-26. PMID 7634801 DOI: 10.1097/00003246-199508000-00004  0.351
1994 Voelkel NF, Tuder R. Interleukin-1 receptor antagonist inhibits pulmonary hypertension induced by inflammation Annals of the New York Academy of Sciences. 725: 104-109. PMID 8030981 DOI: 10.1111/J.1749-6632.1994.Tb39794.X  0.444
1994 Schwarz MI, Lynch DA, Tuder R. Bronchiolitis obliterans: The lone manifestation of rheumatoid arthritis? European Respiratory Journal. 7: 817-820. PMID 8005266 DOI: 10.1183/09031936.94.07040817  0.326
1994 Voelkel NF, Tuder RM, Bridges J, Arend WP. Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline American Journal of Respiratory Cell and Molecular Biology. 11: 664-675. PMID 7946395 DOI: 10.1165/Ajrcmb.11.6.7946395  0.408
1994 Kinnard WV, Tuder R, Papst P, Fisher JH. Regulation of alveolar type II cell differentiation and proliferation in adult rat lung explants. American Journal of Respiratory Cell and Molecular Biology. 11: 416-25. PMID 7917310 DOI: 10.1165/Ajrcmb.11.4.7917310  0.395
1994 Halbower AC, Tuder RM, Franklin WA, Pollock JS, Förstermann U, Abman SH. Maturation-related changes in endothelial nitric oxide synthase immunolocalization in developing ovine lung. The American Journal of Physiology. 267: L585-91. PMID 7526706 DOI: 10.1152/Ajplung.1994.267.5.L585  0.475
1994 Pfister S, Tuder R. Plexogenic Pulmonary Arteriopathy in a Case of Adenocarcinoma of the Prostate with Tumor Emboli to the Lungs Seminars in Respiratory and Critical Care Medicine. 15: 516-521. DOI: 10.1055/S-2007-1006398  0.398
1994 Tuder R. Plexiform Lesions in Primary Pulmonary Hypertension May Represent an Abnormal Form of Angiogenesis Seminars in Respiratory and Critical Care Medicine. 15: 207-214. DOI: 10.1055/S-2007-1006364  0.453
1992 Koike K, Moore FA, Moore EE, Poggetti RS, Tuder RM, Banerjee A. Endotoxin after gut ischemia/reperfusion causes irreversible lung injury. The Journal of Surgical Research. 52: 656-62. PMID 1326681 DOI: 10.1016/0022-4804(92)90145-P  0.327
1990 Tuder RM, Karasek MA, Bensch KG. Cyclic adenosine monophosphate levels and the function of skin microvascular endothelial cells. Journal of Cellular Physiology. 142: 272-283. PMID 1689317 DOI: 10.1002/Jcp.1041420209  0.313
1987 Tuder RM, Young R, Karasek M, Bensch K. Adult cutaneous hemangiomas are composed of nonreplicating endothelial cells. Journal of Investigative Dermatology. 89: 594-597. PMID 3680983 DOI: 10.1111/1523-1747.Ep12461306  0.344
1985 Tuder RM, el Ibrahim R, Godoy CE, De Brito T. Pathology of the human pulmonary paracoccidioidomycosis. Mycopathologia. 92: 179-88. PMID 4088291 DOI: 10.1007/Bf00437631  0.509
1985 Tuder RM. Myocardial infarct in disseminated mucormycosis: case report with special emphasis on the pathogenic mechanisms. Mycopathologia. 89: 81-8. PMID 3990762 DOI: 10.1007/Bf00431474  0.312
Show low-probability matches.