Maike Sander - Publications

Affiliations: 
Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Human Development, Genetics, Cell Biology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wortham M, Ramms B, Zeng C, Benthuysen JR, Sai S, Pollow DP, Liu F, Schlichting M, Harrington AR, Liu B, Prakash TP, Pirie EC, Zhu H, Baghdasarian S, Auwerx J, ... ... Sander M, et al. Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2. Biorxiv : the Preprint Server For Biology. PMID 38464227 DOI: 10.1101/2024.02.24.581864  0.338
2023 Bender RHF, O'Donnell BT, Shergill B, Pham BQ, Tahmouresie S, Sanchez CN, Juat DJ, Hatch MMS, Shirure VS, Wortham M, Nguyen-Ngoc KV, Jun Y, Gaetani R, Christman KL, Teyton L, ... ... Sander M, et al. A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction. Biofabrication. PMID 38128127 DOI: 10.1088/1758-5090/ad17d0  0.323
2023 Urizar AI, Prause M, Ingerslev LR, Wortham M, Sui Y, Sander M, Williams K, Barrès R, Larsen MR, Christensen GL, Billestrup N. Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding. Cell Death & Disease. 14: 399. PMID 37407581 DOI: 10.1038/s41419-023-05906-w  0.391
2023 Wang G, Chiou J, Zeng C, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, ... ... Sander M, et al. Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes. Nature Genetics. PMID 37231096 DOI: 10.1038/s41588-023-01397-9  0.346
2023 Zhu H, Wang G, Nguyen-Ngoc KV, Kim D, Miller M, Goss G, Kovsky J, Harrington AR, Saunders DC, Hopkirk AL, Melton R, Powers AC, Preissl S, Spagnoli FM, Gaulton KJ, ... Sander M, et al. Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. Developmental Cell. PMID 37040771 DOI: 10.1016/j.devcel.2023.03.011  0.511
2023 Magenheim J, Maestro MA, Sharon N, Herrera PL, Murtaugh LC, Kopp J, Sander M, Gu G, Melton DA, Ferrer J, Dor Y. Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors. Cell Stem Cell. 30: 488-497.e3. PMID 37028408 DOI: 10.1016/j.stem.2023.03.003  0.437
2023 Wang G, Chiou J, Zeng C, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, ... ... Sander M, et al. Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes. Biorxiv : the Preprint Server For Biology. PMID 36711922 DOI: 10.1101/2022.12.31.522386  0.334
2022 Nguyen-Ngoc KV, Wortham M, Sander M. Sizing up beta cells made from stem cells. Nature Biotechnology. PMID 35288669 DOI: 10.1038/s41587-022-01271-9  0.362
2021 Shum M, Segawa M, Gharakhanian R, Viñuela A, Wortham M, Baghdasarian S, Wolf DM, Sereda SB, Nocito L, Stiles L, Zhou Z, Gutierrez V, Sander M, Shirihai OS, Liesa M. Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance. Molecular Metabolism. 101403. PMID 34823065 DOI: 10.1016/j.molmet.2021.101403  0.316
2021 Heller S, Li Z, Lin Q, Geusz R, Breunig M, Hohwieler M, Zhang X, Nair GG, Seufferlein T, Hebrok M, Sander M, Julier C, Kleger A, Costa IG. Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation. Communications Biology. 4: 1298. PMID 34789845 DOI: 10.1038/s42003-021-02818-3  0.372
2021 Geusz RJ, Wang A, Lam DK, Vinckier NK, Alysandratos KD, Roberts DA, Wang J, Kefalopoulou S, Ramirez A, Qiu Y, Chiou J, Gaulton KJ, Ren B, Kotton DN, Sander M. Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors. Nature Communications. 12: 6636. PMID 34789735 DOI: 10.1038/s41467-021-26950-0  0.34
2021 Kaestner KH, Campbell-Thompson M, Dor Y, Gill RG, Glaser B, Kim SK, Sander M, Stabler C, Stewart AF, Powers AC. What is a β cell? - Chapter I in the Human Islet Research Network (HIRN) Review Series. Molecular Metabolism. 101323. PMID 34416394 DOI: 10.1016/j.molmet.2021.101323  0.372
2021 Wortham M, Sander M. Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation. Trends in Endocrinology and Metabolism: Tem. 32: 474-487. PMID 34030925 DOI: 10.1016/j.tem.2021.04.011  0.417
2021 Chiou J, Zeng C, Cheng Z, Han JY, Schlichting M, Miller M, Mendez R, Huang S, Wang J, Sui Y, Deogaygay A, Okino ML, Qiu Y, Sun Y, Kudtarkar P, ... ... Sander M, et al. Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk. Nature Genetics. PMID 33795864 DOI: 10.1038/s41588-021-00823-0  0.427
2021 Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qui Y, Yan J, Aylward A, Ren B, Dong PDS, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. Elife. 10. PMID 33544077 DOI: 10.7554/eLife.59067  0.354
2020 Gaertner B, van Heesch S, Schneider-Lunitz V, Schulz JF, Witte F, Blachut S, Nguyen S, Wong R, Matta I, Hübner N, Sander M. A human ESC-based screen identifies a role for the translated lncRNA in pancreatic endocrine differentiation. Elife. 9. PMID 32744504 DOI: 10.7554/Elife.58659  0.426
2020 Vinckier NK, Patel NA, Geusz RJ, Wang A, Wang J, Matta I, Harrington AR, Wortham M, Wetton N, Wang J, Jhala US, Rosenfeld MG, Benner CW, Shih HP, Sander M. LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. Nature Communications. 11: 2082. PMID 32350257 DOI: 10.1038/S41467-020-16017-X  0.447
2020 Ye J, Huang A, Wang H, Zhang AMY, Huang X, Lan Q, Sato T, Goyama S, Kurokawa M, Deng C, Sander M, Schaeffer DF, Li W, Kopp JL, Xie R. PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response. Cell Death & Disease. 11: 187. PMID 32179733 DOI: 10.1038/S41419-020-2371-X  0.505
2020 Gaertner B, Heesch Sv, Schneider-Lunitz V, Schulz JF, Witte F, Blachut S, Nguyen S, Wong R, Matta I, Hübner N, Sander M. Author response: A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation Elife. DOI: 10.7554/Elife.58659.Sa2  0.312
2019 Jun Y, Lee J, Choi S, Yang JH, Sander M, Chung S, Lee SH. In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids. Science Advances. 5: eaax4520. PMID 31807701 DOI: 10.1126/Sciadv.Aax4520  0.385
2019 Jin W, Mulas F, Gaertner B, Sui Y, Wang J, Matta I, Zeng C, Vinckier N, Wang A, Nguyen-Ngoc KV, Chiou J, Kaestner KH, Frazer KA, Carrano AC, Shih HP, ... Sander M, et al. A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells. Iscience. 21: 681-694. PMID 31733514 DOI: 10.1016/J.Isci.2019.10.063  0.389
2019 Gaertner B, Carrano AC, Sander M. Human stem cell models: lessons for pancreatic development and disease. Genes & Development. 33: 1475-1490. PMID 31676735 DOI: 10.1101/Gad.331397.119  0.485
2019 Mills JC, Stanger BZ, Sander M. Nomenclature for cellular plasticity: are the terms as plastic as the cells themselves? The Embo Journal. e103148. PMID 31475380 DOI: 10.15252/Embj.2019103148  0.413
2019 Ibarra Urizar A, Prause M, Wortham M, Sui Y, Thams P, Sander M, Christensen GL, Billestrup N. Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications. Molecular and Cellular Endocrinology. 110524. PMID 31362031 DOI: 10.1016/J.Mce.2019.110524  0.457
2019 Shi C, Pan FC, Kim JN, Washington MK, Padmanabhan C, Meyer CT, Kopp JL, Sander M, Gannon M, Beauchamp RD, Wright CV, Means AL. Differential cell susceptibilities to Kras in the setting of obstructive chronic pancreatitis. Cellular and Molecular Gastroenterology and Hepatology. PMID 31310834 DOI: 10.1016/J.Jcmgh.2019.07.001  0.323
2019 Greenwald WW, Chiou J, Yan J, Qiu Y, Dai N, Wang A, Nariai N, Aylward A, Han JY, Kadakia N, Regue L, Okino ML, Drees F, Kramer D, Vinckier N, ... ... Sander M, et al. Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk. Nature Communications. 10: 2078. PMID 31064983 DOI: 10.1038/S41467-019-09975-4  0.357
2019 WORTHAM M, LIU F, FLEISCHMAN J, WALLACE M, HARRINGTON AR, CHIOU J, GAULTON K, METALLO C, SANDER M. 4-LB: Feeding-Stimulated Regulation of the Epigenome Controls Adaptive Insulin Secretion Diabetes. 68: 4-LB. DOI: 10.2337/Db19-4-Lb  0.378
2019 Ferguson LP, Gatchalian J, Lytle NK, Rajbhandari N, Chambers K, Albini S, Bruneau B, Puri L, Sander M, Lowy A, Hargreaves D, Reya T. Abstract B18: Defining the role of chromatin remodeling complexes in pancreatic cancer stem cells Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-B18  0.413
2018 Wortham M, Benthuysen JR, Wallace M, Savas JN, Mulas F, Divakaruni AS, Liu F, Albert V, Taylor BL, Sui Y, Saez E, Murphy AN, Yates JR, Metallo CM, Sander M. Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function. Cell Reports. 25: 2904-2918.e8. PMID 30517875 DOI: 10.1016/J.Celrep.2018.11.031  0.364
2018 Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Oropeza D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright CEV, Thomas MK, Furuyama K, et al. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon α-cells. Nature Cell Biology. 20: 1267-1277. PMID 30361701 DOI: 10.1038/S41556-018-0216-Y  0.477
2018 Serrill JD, Sander M, Shih HP. Pancreatic Exocrine Tissue Architecture and Integrity are Maintained by E-cadherin During Postnatal Development. Scientific Reports. 8: 13451. PMID 30194315 DOI: 10.1038/S41598-018-31603-2  0.44
2018 Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 29532564 DOI: 10.1002/Dvdy.24626  0.482
2018 Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut. PMID 29363536 DOI: 10.1136/Gutjnl-2017-314426  0.448
2017 Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. PMID 29273451 DOI: 10.1053/J.Gastro.2017.12.007  0.387
2017 Carrano AC, Mulas F, Zeng C, Sander M. Interrogating islets in health and disease with single-cell technologies. Molecular Metabolism. 6: 991-1001. PMID 28951823 DOI: 10.1016/J.Molmet.2017.04.012  0.448
2017 Zeng C, Mulas F, Sui Y, Guan T, Miller N, Tan Y, Liu F, Jin W, Carrano AC, Huising MO, Shirihai OS, Yeo GW, Sander M. Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation. Cell Metabolism. 25: 1160-1175.e11. PMID 28467932 DOI: 10.1016/J.Cmet.2017.04.014  0.481
2017 Wortham M, Sander M. Mechanisms of β-cell functional adaptation to changes in workload. Diabetes, Obesity & Metabolism. 78-86. PMID 27615135 DOI: 10.1111/Dom.12729  0.402
2016 Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, ... ... Sander M, et al. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells. The Journal of Clinical Investigation. PMID 27941246 DOI: 10.1172/Jci88016  0.527
2016 Benthuysen JR, Carrano AC, Sander M. Advances in β cell replacement and regeneration strategies for treating diabetes. The Journal of Clinical Investigation. 126: 3651-3660. PMID 27694741 DOI: 10.1172/Jci87439  0.473
2016 Barrionuevo FJ, Hurtado A, Kim GJ, Real FM, Bakkali M, Kopp JL, Sander M, Scherer G, Burgos M, Jiménez R. Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. Elife. 5. PMID 27328324 DOI: 10.7554/Elife.15635  0.417
2016 Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp JL, Kritzik M, Sicklick JK, Sander M, Grandgenett PM, Hollingsworth MA, et al. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. PMID 27281208 DOI: 10.1038/Nature17988  0.399
2016 Wortham M, Sander M. High T Gives β Cells a Boost. Cell Metabolism. 23: 761-3. PMID 27166938 DOI: 10.1016/J.Cmet.2016.04.015  0.395
2016 Kopp JL, Grompe M, Sander M. Stem cells versus plasticity in liver and pancreas regeneration. Nature Cell Biology. 18: 238-45. PMID 26911907 DOI: 10.1038/Ncb3309  0.466
2016 Shih HP, Panlasigui D, Cirulli V, Sander M. ECM Signaling Regulates Collective Cellular Dynamics to Control Pancreas Branching Morphogenesis. Cell Reports. 14: 169-79. PMID 26748698 DOI: 10.1016/J.Celrep.2015.12.027  0.488
2016 Pan FC, Kim JN, Shi C, Washington MK, Sander M, Gannon M, Beauchamp RD, Wright CV, Means AL. Abstract B19: Kras mutation imparts neoplastic potential on duct cells but not acinar cells in a mouse model of obstructive chronic pancreatitis Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B19  0.408
2016 Lee A, Dubois C, Schaeffer D, Sander M, Kopp J. Abstract A84: PDAC initiation and progression occurs more rapidly from KrasG12D-expressing ductal cells than KrasG12D-expressing acinar cells in the absence of Trp53 Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A84  0.498
2015 Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, et al. Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development (Cambridge, England). 142: 3416-28. PMID 26443638 DOI: 10.1242/Dev.121871  0.363
2015 Shih HP, Seymour PA, Patel NA, Xie R, Wang A, Liu PP, Yeo GW, Magnuson MA, Sander M. A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Reports. PMID 26440894 DOI: 10.1016/J.Celrep.2015.08.082  0.424
2015 Font-Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A, Taniguchi K, Nakagawa H, Valasek MA, Ye L, Kopp JL, Sander M, Carter H, Deisseroth K, Verma IM, et al. Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell. 162: 766-79. PMID 26276631 DOI: 10.1016/J.Cell.2015.07.026  0.32
2015 Jörs S, Jeliazkova P, Ringelhan M, Thalhammer J, Dürl S, Ferrer J, Sander M, Heikenwalder M, Schmid RM, Siveke JT, Geisler F. Lineage fate of ductular reactions in liver injury and carcinogenesis. The Journal of Clinical Investigation. 125: 2445-57. PMID 25915586 DOI: 10.1172/JCI78585  0.318
2015 Wang A, Yue F, Li Y, Xie R, Harper T, Patel NA, Muth K, Palmer J, Qiu Y, Wang J, Lam DK, Raum JC, Stoffers DA, Ren B, Sander M. Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates. Cell Stem Cell. 16: 386-99. PMID 25842977 DOI: 10.1016/J.Stem.2015.02.013  0.475
2015 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C. Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development (Cambridge, England). 142: 871-82. PMID 25715395 DOI: 10.1242/dev.110759  0.437
2015 Xie R, Carrano AC, Sander M. A systems view of epigenetic networks regulating pancreas development and β-cell function. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 7: 1-11. PMID 25644779 DOI: 10.1002/Wsbm.1287  0.443
2015 Taylor BL, Benthuysen J, Sander M. Postnatal β-cell proliferation and mass expansion is dependent on the transcription factor Nkx6.1. Diabetes. 64: 897-903. PMID 25277396 DOI: 10.2337/Db14-0684  0.46
2015 Zeng N, Kassa A, Kopp J, He L, Sander M, Stiles B. Abstract LB-145: Pten deletion in SOX9+ cells synergizes with hepatic injury to drive tumor development in mouse liver Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-145  0.313
2014 Malhotra GK, Zhao X, Edwards E, Kopp JL, Naramura M, Sander M, Band H, Band V. The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. Bmc Developmental Biology. 14: 47. PMID 25527186 DOI: 10.1186/S12861-014-0047-4  0.456
2014 Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M. Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. Plos One. 9: e109171. PMID 25285789 DOI: 10.1371/Journal.Pone.0109171  0.345
2014 Shih HP, Sander M. Pancreas development ex vivo: culturing embryonic pancreas explants on permeable culture inserts, with fibronectin-coated glass microwells, or embedded in three-dimensional Matrigel™. Methods in Molecular Biology (Clifton, N.J.). 1210: 229-37. PMID 25173172 DOI: 10.1007/978-1-4939-1435-7_17  0.352
2014 Benitah SA, Bracken A, Dou Y, Huangfu D, Ivanova N, Koseki H, Laurent L, Lim DA, Meshorer E, Pombo A, Sander M, Xu GL. Stem cell epigenetics: looking forward. Cell Stem Cell. 14: 706-9. PMID 25032261 DOI: 10.1016/J.Stem.2014.05.011  0.399
2014 Kanda S, Tanigawa S, Ohmori T, Taguchi A, Kudo K, Suzuki Y, Sato Y, Hino S, Sander M, Perantoni AO, Sugano S, Nakao M, Nishinakamura R. Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor. Journal of the American Society of Nephrology : Jasn. 25: 2584-95. PMID 24744442 DOI: 10.1681/Asn.2013080896  0.407
2014 Kopp JL, Sander M. New insights into the cell lineage of pancreatic ductal adenocarcinoma: evidence for tumor stem cells in premalignant lesions? Gastroenterology. 146: 24-6. PMID 24275238 DOI: 10.1053/J.Gastro.2013.11.023  0.441
2014 Zeng N, Kopp J, He L, Sander M, Stiles B. Abstract 3900: Pten deletion in SOX9+ cells leads to tumor initiating cell expansion and tumor development in mouse liver Cancer Research. 74: 3900-3900. DOI: 10.1158/1538-7445.Am2014-3900  0.368
2013 Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR. Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: E4456-64. PMID 24191021 DOI: 10.1073/Pnas.1311847110  0.369
2013 Taylor BL, Liu FF, Sander M. Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells. Cell Reports. 4: 1262-75. PMID 24035389 DOI: 10.1016/J.Celrep.2013.08.010  0.473
2013 Shih HP, Wang A, Sander M. Pancreas organogenesis: from lineage determination to morphogenesis. Annual Review of Cell and Developmental Biology. 29: 81-105. PMID 23909279 DOI: 10.1146/Annurev-Cellbio-101512-122405  0.437
2013 Guo S, Dai C, Guo M, Taylor B, Harmon JS, Sander M, Robertson RP, Powers AC, Stein R. Inactivation of specific β cell transcription factors in type 2 diabetes. The Journal of Clinical Investigation. 123: 3305-16. PMID 23863625 DOI: 10.1172/Jci65390  0.482
2013 Jin L, Feng T, Shih HP, Zerda R, Luo A, Hsu J, Mahdavi A, Sander M, Tirrell DA, Riggs AD, Ku HT. Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. Proceedings of the National Academy of Sciences of the United States of America. 110: 3907-12. PMID 23431132 DOI: 10.1073/Pnas.1301889110  0.53
2013 Schaffer AE, Taylor BL, Benthuysen JR, Liu J, Thorel F, Yuan W, Jiao Y, Kaestner KH, Herrera PL, Magnuson MA, May CL, Sander M. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. Plos Genetics. 9: e1003274. PMID 23382704 DOI: 10.1371/Journal.Pgen.1003274  0.755
2013 Xie R, Everett LJ, Lim HW, Patel NA, Schug J, Kroon E, Kelly OG, Wang A, D'Amour KA, Robins AJ, Won KJ, Kaestner KH, Sander M. Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell Stem Cell. 12: 224-37. PMID 23318056 DOI: 10.1016/J.Stem.2012.11.023  0.489
2012 van der Meulen T, Xie R, Kelly OG, Vale WW, Sander M, Huising MO. Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells. Plos One. 7: e52181. PMID 23251699 DOI: 10.1371/Journal.Pone.0052181  0.506
2012 Kopp JL, von Figura G, Mayes E, Liu FF, Dubois CL, Morris JP, Pan FC, Akiyama H, Wright CV, Jensen K, Hebrok M, Sander M. Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell. 22: 737-50. PMID 23201164 DOI: 10.1016/J.Ccr.2012.10.025  0.455
2012 Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, ... ... Sander M, et al. Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metabolism. 16: 435-48. PMID 23040067 DOI: 10.1016/J.Cmet.2012.08.010  0.469
2012 Seymour PA, Shih HP, Patel NA, Freude KK, Xie R, Lim CJ, Sander M. A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. Development (Cambridge, England). 139: 3363-72. PMID 22874919 DOI: 10.1242/Dev.078733  0.513
2012 Wang A, Sander M. Generating cells of the gastrointestinal system: current approaches and applications for the differentiation of human pluripotent stem cells. Journal of Molecular Medicine (Berlin, Germany). 90: 763-71. PMID 22714642 DOI: 10.1007/S00109-012-0923-Y  0.495
2012 Shih HP, Kopp JL, Sandhu M, Dubois CL, Seymour PA, Grapin-Botton A, Sander M. A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development (Cambridge, England). 139: 2488-99. PMID 22675211 DOI: 10.1242/Dev.078634  0.495
2011 Schaffer AE, Yang AJ, Thorel F, Herrera PL, Sander M. Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance. Molecular Endocrinology (Baltimore, Md.). 25: 1904-14. PMID 21964593 DOI: 10.1210/Me.2011-1010  0.726
2011 Dubois CL, Shih HP, Seymour PA, Patel NA, Behrmann JM, Ngo V, Sander M. Sox9-haploinsufficiency causes glucose intolerance in mice. Plos One. 6: e23131. PMID 21829703 DOI: 10.1371/Journal.Pone.0023131  0.525
2011 Carpentier R, Suñer RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 141: 1432-8, 1438.e1-4. PMID 21708104 DOI: 10.1053/J.Gastro.2011.06.049  0.474
2011 Dorrell C, Erker L, Schug J, Kopp JL, Canaday PS, Fox AJ, Smirnova O, Duncan AW, Finegold MJ, Sander M, Kaestner KH, Grompe M. Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes & Development. 25: 1193-203. PMID 21632826 DOI: 10.1101/Gad.2029411  0.435
2011 Kopp JL, Dubois CL, Hao E, Thorel F, Herrera PL, Sander M. Progenitor cell domains in the developing and adult pancreas. Cell Cycle (Georgetown, Tex.). 10: 1921-7. PMID 21558806 DOI: 10.4161/Cc.10.12.16010  0.524
2011 Seymour PA, Sander M. Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development. Diabetes. 60: 364-76. PMID 21270248 DOI: 10.2337/Db10-1068  0.565
2011 Kopp JL, Dubois CL, Schaffer AE, Hao E, Shih HP, Seymour PA, Ma J, Sander M. Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development (Cambridge, England). 138: 653-65. PMID 21266405 DOI: 10.1242/Dev.056499  0.766
2010 Schaffer AE, Freude KK, Nelson SB, Sander M. Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Developmental Cell. 18: 1022-9. PMID 20627083 DOI: 10.1016/J.Devcel.2010.05.015  0.751
2009 Wang S, Jensen JN, Seymour PA, Hsu W, Dor Y, Sander M, Magnuson MA, Serup P, Gu G. Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proceedings of the National Academy of Sciences of the United States of America. 106: 9715-20. PMID 19487660 DOI: 10.1073/Pnas.0904247106  0.537
2008 Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M. A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Developmental Biology. 323: 19-30. PMID 18723011 DOI: 10.1016/J.Ydbio.2008.07.034  0.502
2008 Jonckheere N, Mayes E, Shih HP, Li B, Lioubinski O, Dai X, Sander M. Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. Developmental Biology. 318: 224-35. PMID 18452912 DOI: 10.1016/J.Ydbio.2008.03.014  0.505
2007 Nelson SB, Schaffer AE, Sander M. The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells. Development (Cambridge, England). 134: 2491-500. PMID 17537793 DOI: 10.1242/Dev.002691  0.754
2007 Seymour PA, Freude KK, Tran MN, Mayes EE, Jensen J, Kist R, Scherer G, Sander M. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proceedings of the National Academy of Sciences of the United States of America. 104: 1865-70. PMID 17267606 DOI: 10.1073/Pnas.0609217104  0.547
2005 Pedersen JK, Nelson SB, Jorgensen MC, Henseleit KD, Fujitani Y, Wright CV, Sander M, Serup P. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Developmental Biology. 288: 487-501. PMID 16297379 DOI: 10.1016/J.Ydbio.2005.10.001  0.367
2005 Henseleit KD, Nelson SB, Kuhlbrodt K, Hennings JC, Ericson J, Sander M. NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas. Development (Cambridge, England). 132: 3139-49. PMID 15944193 DOI: 10.1242/Dev.01875  0.544
2005 Nelson SB, Janiesch C, Sander M. Expression of Nkx6 genes in the hindbrain and gut of the developing mouse. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 787-90. PMID 15928328 DOI: 10.1369/Jhc.5B6619.2005  0.317
2005 Cai J, Qi Y, Hu X, Tan M, Liu Z, Zhang J, Li Q, Sander M, Qiu M. Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron. 45: 41-53. PMID 15629701 DOI: 10.1016/J.Neuron.2004.12.028  0.343
2004 Mellitzer G, Martín M, Sidhoum-Jenny M, Orvain C, Barths J, Seymour PA, Sander M, Gradwohl G. Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Molecular Endocrinology (Baltimore, Md.). 18: 2765-76. PMID 15297605 DOI: 10.1210/Me.2004-0243  0.557
2004 Matsuoka TA, Artner I, Henderson E, Means A, Sander M, Stein R. The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proceedings of the National Academy of Sciences of the United States of America. 101: 2930-3. PMID 14973194 DOI: 10.1073/Pnas.0306233101  0.464
2003 Liu R, Cai J, Hu X, Tan M, Qi Y, German M, Rubenstein J, Sander M, Qiu M. Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Development (Cambridge, England). 130: 6221-31. PMID 14602683 DOI: 10.1242/Dev.00868  0.313
2003 Müller M, Jabs N, Lorke DE, Fritzsch B, Sander M. Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons. Development (Cambridge, England). 130: 5815-26. PMID 14534138 DOI: 10.1242/Dev.00815  0.352
2003 Pattyn A, Vallstedt A, Dias JM, Sander M, Ericson J. Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Development (Cambridge, England). 130: 4149-59. PMID 12874134 DOI: 10.1242/Dev.00641  0.389
2003 Lioubinski O, Müller M, Wegner M, Sander M. Expression of Sox transcription factors in the developing mouse pancreas. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 227: 402-8. PMID 12815626 DOI: 10.1002/Dvdy.10311  0.466
2001 Vallstedt A, Muhr J, Pattyn A, Pierani A, Mendelsohn M, Sander M, Jessell TM, Ericson J. Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification. Neuron. 31: 743-55. PMID 11567614 DOI: 10.1016/S0896-6273(01)00412-3  0.38
1998 Sander M, Griffen SC, Huang J, German MS. A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets. Proceedings of the National Academy of Sciences of the United States of America. 95: 11572-7. PMID 9751707 DOI: 10.1073/Pnas.95.20.11572  0.417
1997 Sander M, Neubüser A, Kalamaras J, Ee HC, Martin GR, German MS. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes & Development. 11: 1662-73. PMID 9224716 DOI: 10.1101/Gad.11.13.1662  0.429
1997 Sander M, German MS. The β cell transcription factors and development of the pancreas Journal of Molecular Medicine. 75: 327-340. PMID 9181474 DOI: 10.1007/S001090050118  0.514
1995 Mellon SH, Compagnone N, Sander M, Cover C, Ganten D, Djavidani B. Rodent models for studying steroids and hypertension: from fetal development to cells in culture. Steroids. 60: 59-64. PMID 7792817 DOI: 10.1016/0039-128X(94)00020-D  0.422
1994 Sander M, Ganten D, Mellon SH. Role of adrenal renin in the regulation of adrenal steroidogenesis by corticotropin. Proceedings of the National Academy of Sciences of the United States of America. 91: 148-52. PMID 8278356 DOI: 10.1073/Pnas.91.1.148  0.337
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