Pran K. Datta - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Cell Biology, Molecular Biology, Oncology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang BH, Wang C, Dong W, Chen X, Leng C, Luo X, Dong SL, Yin P, Zhang BX, Datta PK, Chen XP. A Novel Approach for Monitoring TGF-ß Signaling in vivo in Colon Cancer. Carcinogenesis. PMID 33367515 DOI: 10.1093/carcin/bgaa142  0.43
2020 Agarwal S, Behring M, Kim HG, Chandrashekar DS, Chakravarthi BVSK, Gupta N, Bajpai P, Elkholy A, Al Diffalha S, Datta PK, Heslin MJ, Varambally S, Manne U. TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status. Molecular Oncology. PMID 33037736 DOI: 10.1002/1878-0261.12821  0.375
2020 Vu T, Yang S, Datta PK. MiR-216b/Smad3/BCL-2 Axis Is Involved in Smoking-Mediated Drug Resistance in Non-Small Cell Lung Cancer. Cancers. 12. PMID 32668597 DOI: 10.3390/Cancers12071879  0.417
2020 Liao Z, Chen L, Zhang X, Zhang H, Tan X, Dong K, Lu X, Zhu H, Liu Q, Zhang Z, Ding Z, Dong W, Zhu P, Chu L, Liang H, ... Datta PK, et al. PTPRε Acts as a Metastatic Promoter in Hepatocellular Carcinoma by Facilitating Recruitment of SMAD3 to TGF-β Receptor 1. Hepatology (Baltimore, Md.). PMID 31903610 DOI: 10.1002/Hep.31104  0.496
2018 Jin L, Chang C, Pawlik KM, Datta A, Johnson LM, Vu T, Napoli JL, Datta PK. STRAP Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis. Stem Cells (Dayton, Ohio). PMID 29781215 DOI: 10.1002/Stem.2854  0.36
2018 Vu T, Datta A, Jin L, Datta PK. Abstract 5058: STRAP-induced Wnt/ß-catenin signaling is important in inactivated Apc-mediated tumorigenicity and stemness of colorectal cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-5058  0.417
2017 Vu T, Datta PK. Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis. Cancers. 9. PMID 29258163 DOI: 10.3390/Cancers9120171  0.474
2017 Zhang W, Zhang B, Vu T, Yuan G, Zhang B, Chen X, Manne U, Datta PK. Molecular characterization of pro-metastatic functions of β4-integrin in colorectal cancer. Oncotarget. 8: 92333-92345. PMID 29190919 DOI: 10.18632/Oncotarget.21290  0.458
2017 Jin L, Vu T, Yuan G, Datta PK. STRAP promotes stemness of human colorectal cancer via epigenetic regulation of the NOTCH pathway. Cancer Research. PMID 28827371 DOI: 10.1158/0008-5472.Can-17-0286  0.469
2016 Rachakonda G, Vu T, Jin L, Samanta D, Datta PK. Role of TGF-β-induced Claudin-4 expression through c-Jun signaling in non-small cell lung cancer. Cellular Signalling. PMID 27424491 DOI: 10.1016/J.Cellsig.2016.07.006  0.546
2016 Vu T, Jin L, Datta PK. Effect of Cigarette Smoking on Epithelial to Mesenchymal Transition (EMT) in Lung Cancer. Journal of Clinical Medicine. 5. PMID 27077888 DOI: 10.3390/Jcm5040044  0.308
2016 Ding ZY, Jin GN, Wang W, Sun YM, Chen WX, Chen L, Liang HF, Datta PK, Zhang MZ, Zhang B, Chen XP. Activin A-Smad Signaling Mediates Connective Tissue Growth Factor Synthesis in Liver Progenitor Cells. International Journal of Molecular Sciences. 17. PMID 27011166 DOI: 10.3390/Ijms17030408  0.349
2016 Yuan G, Zhang B, Yang S, Jin L, Datta A, Bae S, Chen X, Datta PK. Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling. Oncotarget. PMID 26910283 DOI: 10.18632/Oncotarget.7532  0.534
2016 Jin L, Vu TT, Datta PK. Abstract 1709: STRAP mediates the stemness of human colorectal cancer cells by epigenetic regulation of Notch pathway Cancer Research. 76: 1709-1709. DOI: 10.1158/1538-7445.Am2016-1709  0.373
2015 Yang S, Cho YJ, Jin L, Yuan G, Datta A, Buckhaults P, Datta PK. An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC. Oncotarget. PMID 26356817 DOI: 10.18632/Oncotarget.4893  0.465
2014 Jin L, Datta PK. Oncogenic STRAP functions as a novel negative regulator of E-cadherin and p21(Cip1) by modulating the transcription factor Sp1. Cell Cycle (Georgetown, Tex.). 13: 3909-20. PMID 25483064 DOI: 10.4161/15384101.2014.973310  0.402
2014 Ding ZY, Jin GN, Wang W, Chen WX, Wu YH, Ai X, Chen L, Zhang WG, Liang HF, Laurence A, Zhang MZ, Datta PK, Zhang B, Chen XP. Reduced expression of transcriptional intermediary factor 1 gamma promotes metastasis and indicates poor prognosis of hepatocellular carcinoma. Hepatology (Baltimore, Md.). 60: 1620-36. PMID 24954480 DOI: 10.1002/Hep.27273  0.432
2014 Ding ZY, Liang HF, Jin GN, Chen WX, Wang W, Datta PK, Zhang MZ, Zhang B, Chen XP. Smad6 suppresses the growth and self-renewal of hepatic progenitor cells. Journal of Cellular Physiology. 229: 651-60. PMID 24446200 DOI: 10.1002/Jcp.24488  0.496
2014 Zhang B, Zhang B, Chen X, Bae S, Singh K, Washington MK, Datta PK. Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway. British Journal of Cancer. 110: 946-57. PMID 24384683 DOI: 10.1038/Bjc.2013.789  0.412
2013 Ai X, Wu Y, Zhang W, Zhang Z, Jin G, Zhao J, Yu J, Lin Y, Zhang W, Liang H, Datta PK, Zhang M, Zhang B, Chen X. Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer. Cancer Biology & Therapy. 14: 1059-67. PMID 24025354 DOI: 10.4161/Cbt.26427  0.51
2013 Ding ZY, Jin GN, Liang HF, Wang W, Chen WX, Datta PK, Zhang MZ, Zhang B, Chen XP. Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling. Cellular Signalling. 25: 1981-92. PMID 23727026 DOI: 10.1016/J.Cellsig.2013.05.027  0.466
2012 Nagathihalli NS, Massion PP, Gonzalez AL, Lu P, Datta PK. Smoking induces epithelial-to-mesenchymal transition in non-small cell lung cancer through HDAC-mediated downregulation of E-cadherin. Molecular Cancer Therapeutics. 11: 2362-72. PMID 22933707 DOI: 10.1158/1535-7163.Mct-12-0107  0.354
2012 Samanta D, Kaufman J, Carbone DP, Datta PK. Long-term smoking mediated down-regulation of Smad3 induces resistance to carboplatin in non-small cell lung cancer. Neoplasia (New York, N.Y.). 14: 644-55. PMID 22904681 DOI: 10.1593/Neo.12548  0.437
2012 Samanta D, Gonzalez AL, Nagathihalli N, Ye F, Carbone DP, Datta PK. Smoking attenuates transforming growth factor-β-mediated tumor suppression function through downregulation of Smad3 in lung cancer. Cancer Prevention Research (Philadelphia, Pa.). 5: 453-63. PMID 22232600 DOI: 10.1158/1940-6207.Capr-11-0313  0.475
2012 Samanta D, Datta PK. Alterations in the Smad pathway in human cancers. Frontiers in Bioscience (Landmark Edition). 17: 1281-93. PMID 22201803 DOI: 10.2741/3986  0.551
2012 Samanta D, Datta PK. Abstract 819: Chronic smoking increases tumorigenicity and imparts resistance to platinum-based chemotherapy partly by down-regulating Smad3 in non-small cell lung cancer Cancer Research. 72: 819-819. DOI: 10.1158/1538-7445.Am2012-819  0.476
2011 Halder SK, Cho YJ, Datta A, Anumanthan G, Ham AJ, Carbone DP, Datta PK. Elucidating the mechanism of regulation of transforming growth factor β Type II receptor expression in human lung cancer cell lines. Neoplasia (New York, N.Y.). 13: 912-22. PMID 22028617 DOI: 10.1593/Neo.11576  0.53
2011 Kashikar ND, Zhang W, Massion PP, Gonzalez AL, Datta PK. Role of STRAP in regulating GSK3β function and Notch3 stabilization. Cell Cycle (Georgetown, Tex.). 10: 1639-54. PMID 21502811 DOI: 10.4161/Cc.10.10.15630  0.716
2011 Reiner J, Ye F, Kashikar ND, Datta PK. STRAP regulates c-Jun ubiquitin-mediated proteolysis and cellular proliferation. Biochemical and Biophysical Research Communications. 407: 372-7. PMID 21397588 DOI: 10.1016/J.Bbrc.2011.03.028  0.696
2011 Reiner JE, Datta PK. TGF-beta-dependent and -independent roles of STRAP in cancer. Frontiers in Bioscience (Landmark Edition). 16: 105-15. PMID 21196161 DOI: 10.2741/3678  0.559
2011 Samanta D, Gonzalez A, Datta PK. Abstract 1332: Cigarette smoking attenuates TGF-β-mediated tumor suppression function through down-regulation of Smad3 in lung cancer Cancer Research. 71: 1332-1332. DOI: 10.1158/1538-7445.Am2011-1332  0.467
2010 Rachakonda G, Sekhar KR, Jowhar D, Samson PC, Wikswo JP, Beauchamp RD, Datta PK, Freeman ML. Increased cell migration and plasticity in Nrf2-deficient cancer cell lines. Oncogene. 29: 3703-14. PMID 20440267 DOI: 10.1038/Onc.2010.118  0.558
2010 Nagaraj NS, Datta PK. Targeting the transforming growth factor-beta signaling pathway in human cancer. Expert Opinion On Investigational Drugs. 19: 77-91. PMID 20001556 DOI: 10.1517/13543780903382609  0.541
2010 Zhang B, Halder SK, Kashikar ND, Cho YJ, Datta A, Gorden DL, Datta PK. Antimetastatic role of Smad4 signaling in colorectal cancer. Gastroenterology. 138: 969-80.e1-3. PMID 19909744 DOI: 10.1053/J.Gastro.2009.11.004  0.74
2010 Kashikar ND, Reiner J, Datta A, Datta PK. Serine threonine receptor-associated protein (STRAP) plays a role in the maintenance of mesenchymal morphology. Cellular Signalling. 22: 138-49. PMID 19781628 DOI: 10.1016/J.Cellsig.2009.09.024  0.746
2009 Zhang B, Halder SK, Zhang S, Datta PK. Targeting transforming growth factor-beta signaling in liver metastasis of colon cancer. Cancer Letters. 277: 114-20. PMID 19147275 DOI: 10.1016/J.Canlet.2008.11.035  0.539
2008 Halder SK, Rachakonda G, Deane NG, Datta PK. Smad7 induces hepatic metastasis in colorectal cancer. British Journal of Cancer. 99: 957-65. PMID 18781153 DOI: 10.1038/Sj.Bjc.6604562  0.521
2007 Shiou SR, Singh AB, Moorthy K, Datta PK, Washington MK, Beauchamp RD, Dhawan P. Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. Cancer Research. 67: 1571-9. PMID 17308096 DOI: 10.1158/0008-5472.Can-06-1680  0.592
2006 Anumanthan G, Halder SK, Friedman DB, Datta PK. Oncogenic serine-threonine kinase receptor-associated protein modulates the function of Ewing sarcoma protein through a novel mechanism. Cancer Research. 66: 10824-32. PMID 17108118 DOI: 10.1158/0008-5472.Can-06-1599  0.537
2006 Shiou SR, Datta PK, Dhawan P, Law BK, Yingling JM, Dixon DA, Beauchamp RD. Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-beta. The Journal of Biological Chemistry. 281: 33971-81. PMID 16959768 DOI: 10.1074/Jbc.M607010200  0.568
2006 Halder SK, Anumanthan G, Maddula R, Mann J, Chytil A, Gonzalez AL, Washington MK, Moses HL, Beauchamp RD, Datta PK. Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis. Cancer Research. 66: 6156-66. PMID 16778189 DOI: 10.1158/0008-5472.Can-05-3261  0.601
2006 Grau AM, Datta PK, Zi J, Halder SK, Beauchamp RD. Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells. Cellular Signalling. 18: 1041-50. PMID 16288847 DOI: 10.1016/J.Cellsig.2005.08.021  0.509
2005 Anumanthan G, Halder SK, Osada H, Takahashi T, Massion PP, Carbone DP, Datta PK. Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. British Journal of Cancer. 93: 1157-67. PMID 16251876 DOI: 10.1038/Sj.Bjc.6602831  0.552
2005 Halder SK, Beauchamp RD, Datta PK. A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia (New York, N.Y.). 7: 509-21. PMID 15967103 DOI: 10.1593/Neo.04640  0.543
2005 Halder SK, Beauchamp RD, Datta PK. Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis. Experimental Cell Research. 307: 231-46. PMID 15922743 DOI: 10.1016/J.Yexcr.2005.03.009  0.556
2004 Mithani SK, Balch GC, Shiou SR, Whitehead RH, Datta PK, Beauchamp RD. Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells. The Journal of Surgical Research. 117: 296-305. PMID 15047135 DOI: 10.1016/S0022-4804(03)00335-4  0.549
2003 Parker MA, Deane NG, Thompson EA, Whitehead RH, Mithani SK, Washington MK, Datta PK, Dixon DA, Beauchamp RD. Over-expression of cyclin D1 regulates Cdk4 protein synthesis. Cell Proliferation. 36: 347-60. PMID 14710852 DOI: 10.1046/J.1365-2184.2003.00290.X  0.351
2001 Saha D, Datta PK, Beauchamp RD. Oncogenic ras represses transforming growth factor-beta /Smad signaling by degrading tumor suppressor Smad4. The Journal of Biological Chemistry. 276: 29531-7. PMID 11371552 DOI: 10.1074/Jbc.M100069200  0.529
2000 Datta PK, Blake MC, Moses HL. Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1. The Journal of Biological Chemistry. 275: 40014-9. PMID 11054406 DOI: 10.1074/Jbc.C000508200  0.499
2000 Datta PK, Moses HL. STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling. Molecular and Cellular Biology. 20: 3157-67. PMID 10757800 DOI: 10.1128/Mcb.20.9.3157-3167.2000  0.534
1999 Saha D, Datta PK, Sheng H, Morrow JD, Wada M, Moses HL, Beauchamp RD. Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. Neoplasia (New York, N.Y.). 1: 508-17. PMID 10935498 DOI: 10.1038/Sj.Neo.7900051  0.526
1999 Datta PK, Chytil A, Gorska AE, Moses HL. Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling. The Journal of Biological Chemistry. 273: 34671-4. PMID 9856985 DOI: 10.1074/Jbc.273.52.34671  0.536
1998 Engel ME, Datta PK, Moses HL. Signal transduction by transforming growth factor-β: A cooperative paradigm with extensive negative regulation. Journal of Cellular Biochemistry. 72: 111-122. PMID 29345828 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<111::Aid-Jcb15>3.0.Co;2-5  0.51
1998 Engel ME, Datta PK, Moses HL. RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation. The Journal of Biological Chemistry. 273: 9921-6. PMID 9545335 DOI: 10.1074/Jbc.273.16.9921  0.517
1995 Datta PK, Raychaudhuri P, Bagchi S. Association of p107 with Sp1: Genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcription Molecular and Cellular Biology. 15: 5444-5452. PMID 7565695 DOI: 10.1128/Mcb.15.10.5444  0.301
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