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Narcis I. Popescu, Ph.D. - Publications

Affiliations: 
2010 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Pathology, Cell Biology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Keshari RS, Popescu NI, Silasi R, Regmi G, Lupu C, Simmons JH, Ricardo A, Coggeshall KM, Lupu F. Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34507997 DOI: 10.1073/pnas.2104347118  0.592
2021 Popescu NI, Lupu C, Lupu F. Disseminated intravascular coagulation and its immune mechanisms. Blood. PMID 34428280 DOI: 10.1182/blood.2020007208  0.57
2020 Keshari RS, Silasi R, Popescu NI, Regmi G, Chaaban H, Lambris JD, Lupu C, Mollnes TE, Lupu F. CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis. Journal of Thrombosis and Haemostasis : Jth. PMID 33174372 DOI: 10.1111/jth.15162  0.526
2020 Popescu NI, Keshari RS, Cochran J, Coggeshall KM, Lupu F. C3 Opsonization of Anthrax Bacterium and Peptidoglycan Supports Recognition and Activation of Neutrophils. Microorganisms. 8. PMID 32668703 DOI: 10.3390/microorganisms8071039  0.53
2019 Keshari RS, Silasi R, Popescu NI, Georgescu C, Chaaban H, Lupu C, McCarty OJT, Esmon CT, Lupu F. Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of E. coli sepsis. Journal of Thrombosis and Haemostasis : Jth. PMID 31549765 DOI: 10.1111/Jth.14642  0.589
2019 Popescu NI, Girton A, Burgett T, Lovelady K, Coggeshall KM. Monocyte procoagulant responses to anthrax peptidoglycan are reinforced by proinflammatory cytokine signaling. Blood Advances. 3: 2436-2447. PMID 31416821 DOI: 10.1182/Bloodadvances.2019000513  0.416
2018 Popescu NI, Silasi R, Keshari RS, Girton A, Burgett T, Zeerleder SS, Gailani D, Gruber A, Lupu F, Coggeshall KM. Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways. Blood. PMID 29921614 DOI: 10.1182/Blood-2017-10-813618  0.649
2018 Girton AW, Popescu NI, Keshari RS, Burgett T, Lupu F, Coggeshall KM. Serum amyloid P and IgG exhibit differential capabilities in the activation of the innate immune system in response topeptidoglycan. Infection and Immunity. PMID 29531132 DOI: 10.1128/Iai.00076-18  0.576
2018 Langer M, Girton AW, Popescu NI, Burgett T, Metcalf JP, Coggeshall KM. Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2. Plos One. 13: e0193207. PMID 29474374 DOI: 10.1371/Journal.Pone.0193207  0.331
2017 Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F. Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28720697 DOI: 10.1073/Pnas.1706818114  0.621
2016 Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell. PMID 27374331 DOI: 10.1016/J.Cell.2016.05.076  0.359
2015 Silasi-Mansat R, Zhu H, Georgescu C, Popescu N, Keshari RS, Peer G, Lupu C, Taylor FB, Pereira HA, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases early fibrogenic events in the lung of septic baboons. Journal of Cellular and Molecular Medicine. PMID 26337158 DOI: 10.1111/Jcmm.12667  0.634
2015 Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D'Souza P, Lim YP, Lupu F. Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury. Blood. 125: 2286-96. PMID 25631771 DOI: 10.1182/Blood-2014-06-582759  0.574
2015 Keshari RS, Silasi-Mansat R, Popescu NI, Langer M, Chaaban H, Lupu C, Coggeshall MK, DeMarco S, Lupu F. Complement C5 Inhibition Blocks the Cytokine Storm and Consumptive Coagulopathy By Decreasing Lipopolysaccharide (LPS) Release in E. coli Sepsis Blood. 126: 765-765. DOI: 10.1182/Blood.V126.23.765.765  0.628
2014 Keshari RS, Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Chaaban H, Lambris JD, Polf H, Lupu C, Kinasewitz G, Lupu F. Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis. American Journal of Respiratory Cell and Molecular Biology. 50: 439-50. PMID 24066737 DOI: 10.1165/Rcmb.2013-0219Oc  0.606
2014 Keshari R, Silasi-Mansat R, Popescu NI, Chaaban H, Lupu C, DeMarco SJ, Lupu F. A Novel C5 Complement Inhibitor Protects Against Sepsis-Induced Activation of Complement, Coagulation and Inflammation and Provides Survival Benefit in E. coli Sepsis Blood. 124: 112-112. DOI: 10.1182/Blood.V124.21.112.112  0.622
2013 Sun D, Popescu NI, Raisley B, Keshari RS, Dale GL, Lupu F, Coggeshall KM. Bacillus anthracis peptidoglycan activates human platelets through FcγRII and complement. Blood. 122: 571-9. PMID 23733338 DOI: 10.1182/Blood-2013-02-486613  0.605
2013 Chaaban H, Keshari R, Mehta-D'Souza P, Silasi-Mansat R, Popescu NI, Lupu F. Protective Mechanisms Of Inter-Alpha Inhibitor Protein On Extracellular Histone Toxicity Blood. 122: 19-19. DOI: 10.1182/Blood.V122.21.19.19  0.566
2012 Popescu NI, Merrill JT, Lupu F. Inhibitory Autoantibodies to Protein Disulfide Isomerase From Systemic Lupus Erythematosus Patients Are Prothrombotic Blood. 120: 392-392. DOI: 10.1182/Blood.V120.21.392.392  0.581
2011 Lupu C, Zhu H, Popescu NI, Wren JD, Lupu F. Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen. Blood. 118: 4463-71. PMID 21868574 DOI: 10.1182/blood-2011-05-355370  0.56
2011 Zhang X, Yu H, Lou JR, Zheng J, Zhu H, Popescu NI, Lupu F, Lind SE, Ding WQ. MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells. The Journal of Biological Chemistry. 286: 1429-35. PMID 21059650 DOI: 10.1074/Jbc.M110.146530  0.528
2011 Lupu F, Zhu H, Silasi-Mansat R, Georgescu C, Popescu N, Peer G, Lupu C, Taylor F, Kinasewitz G, Lambris J. Sepsis-induced lung fibrosis in baboons is reduced by the treatment with a complement inhibitor Critical Care. 15: 34. DOI: 10.1186/Cc10403  0.575
2010 Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE, Taylor FB, Kinasewitz G, Lambris JD, Lupu F. Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis Blood. 116: 1002-1010. PMID 20466856 DOI: 10.1182/Blood-2010-02-269746  0.636
2010 Popescu NI, Lupu C, Lupu F. Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood. 116: 993-1001. PMID 20448108 DOI: 10.1182/Blood-2009-10-249607  0.567
2010 Popescu NI, Lupu C, Lupu F. Role of PDI in regulating tissue factor: FVIIa activity. Thrombosis Research. 125: S38-41. PMID 20163832 DOI: 10.1016/J.Thromres.2010.01.034  0.552
2010 Popescu NI, Lupu C, Lupu F. Calcium Ionophore-Induced Tissue Factor (TF) Decryption Induces TF Immobilization Into Lipid Rafts and Negative Regulation of TF Procoagulant Activity. Blood. 116: 1131-1131. DOI: 10.1182/Blood.V116.21.1131.1131  0.569
2010 Lupu F, Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE. Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of E. coli sepsis Molecular Immunology. 47: 2289-2289. DOI: 10.1016/J.Molimm.2010.05.269  0.582
2007 Tang H, Ivanciu L, Popescu N, Peer G, Hack E, Lupu C, Taylor FB, Lupu F. Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor American Journal of Pathology. 171: 1066-1077. PMID 17640967 DOI: 10.2353/Ajpath.2007.070104  0.623
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