Matthew B. Soellner - Publications

Affiliations: 
Medicinal Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Selective Protease Substrates, Substrate-competitive Kinase Inhibitors, Peptidomimetics for Disruption of Protein-Protein Interactions
Website:
http://sitemaker.umich.edu/medchemfaculty/Matthew_Soellner

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Agius MP, Ko KS, Johnson TK, Kwarcinski FE, Phadke S, Lachacz EJ, Soellner MB. Selective Proteolysis to Study the Global Conformation and Regulatory Mechanisms of c-Src Kinase. Acs Chemical Biology. PMID 31287657 DOI: 10.1021/Acschembio.9B00306  0.341
2016 Johnson TK, Soellner MB. Bivalent inhibitors of c-Src tyrosine kinase that bind a regulatory domain. Bioconjugate Chemistry. PMID 27266260 DOI: 10.1021/Acs.Bioconjchem.6B00243  0.352
2016 Gilani R, Phadke S, Bao LW, Lachacz E, Dziubinski M, Brandvold K, Steffey M, Kwarcinski F, Graveel CR, Kidwell KM, Merajver SD, Soellner MB. UM-164: a potent c-Src/p38 kinase inhibitor with in vivo activity against triple negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27154914 DOI: 10.1158/1078-0432.Ccr-15-2158  0.35
2016 Kwarcinski FE, Brandvold KR, Phadke S, Beleh OM, Johnson TK, Meagher JL, Seeliger MA, Stuckey JA, Soellner MB. Conformation-selective analogs of dasatinib reveal insight into kinase inhibitor binding and selectivity. Acs Chemical Biology. PMID 26895387 DOI: 10.1021/Acschembio.5B01018  0.358
2015 Larsen BJ, Sun Z, Lachacz E, Khomutnyk Y, Soellner MB, Nagorny P. Synthesis and Biological Evaluation of Lactimidomycin and Its Analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26577990 DOI: 10.1002/Chem.201503527  0.333
2015 Kwarcinski FE, Steffey ME, Fox CC, Soellner MB. Discovery of Bivalent Kinase Inhibitors via Enzyme-Templated Fragment Elaboration. Acs Medicinal Chemistry Letters. 6: 898-901. PMID 26286460 DOI: 10.1021/Acsmedchemlett.5B00167  0.416
2015 Brandvold KR, Santos SM, Breen ME, Lachacz EJ, Steffey ME, Soellner MB. Exquisitely Specific Bisubstrate Inhibitors of c-Src Kinase. Acs Chemical Biology. 10: 1387-91. PMID 25793938 DOI: 10.1021/Cb501048B  0.632
2015 Breen ME, Soellner MB. Small molecule substrate phosphorylation site inhibitors of protein kinases: approaches and challenges. Acs Chemical Biology. 10: 175-89. PMID 25494294 DOI: 10.1021/Cb5008376  0.388
2015 Gilani RA, Brandvold KR, Bao LW, Phadke S, Steffey ME, Soellner MB, Merajver SD. Abstract 5536: KB-164, a novel and highly potent Src family kinase inhibitor, reduces cancer cell invasion and abrogates downstream oncogenic pathways in triple negative breast cancer Cancer Research. 75: 5536-5536. DOI: 10.1158/1538-7445.Am2015-5536  0.304
2014 Agius MP, Soellner MB. Modulating noncatalytic function with kinase inhibitors. Chemistry & Biology. 21: 569-71. PMID 24856138 DOI: 10.1016/J.Chembiol.2014.05.005  0.393
2014 Breen ME, Steffey ME, Lachacz EJ, Kwarcinski FE, Fox CC, Soellner MB. Substrate activity screening with kinases: discovery of small-molecule substrate-competitive c-Src inhibitors. Angewandte Chemie (International Ed. in English). 53: 7010-3. PMID 24797781 DOI: 10.1002/Anie.201311096  0.386
2014 Bremmer SC, McNeil AJ, Soellner MB. Enzyme-triggered gelation: targeting proteases with internal cleavage sites. Chemical Communications (Cambridge, England). 50: 1691-3. PMID 24394494 DOI: 10.1039/C3Cc48132H  0.345
2013 Ko KS, Steffey ME, Brandvold KR, Soellner MB. Development of a chimeric c-Src kinase and HDAC inhibitor. Acs Medicinal Chemistry Letters. 4: 779-783. PMID 24015327 DOI: 10.1021/Ml400175D  0.354
2013 Rabuck JN, Hyung SJ, Ko KS, Fox CC, Soellner MB, Ruotolo BT. Activation state-selective kinase inhibitor assay based on ion mobility-mass spectrometry. Analytical Chemistry. 85: 6995-7002. PMID 23845095 DOI: 10.1021/Ac4012655  0.412
2012 Kwarcinski FE, Fox CC, Steffey ME, Soellner MB. Irreversible inhibitors of c-Src kinase that target a nonconserved cysteine. Acs Chemical Biology. 7: 1910-7. PMID 22928736 DOI: 10.1021/Cb300337U  0.376
2012 Brandvold KR, Steffey ME, Fox CC, Soellner MB. Development of a highly selective c-Src kinase inhibitor. Acs Chemical Biology. 7: 1393-8. PMID 22594480 DOI: 10.1021/Cb300172E  0.372
2008 Tam A, Soellner MB, Raines RT. Electronic and steric effects on the rate of the traceless Staudinger ligation. Organic & Biomolecular Chemistry. 6: 1173-5. PMID 18362954 DOI: 10.1039/B802336K  0.625
2007 Tam A, Arnold U, Soellner MB, Raines RT. Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. Journal of the American Chemical Society. 129: 12670-1. PMID 17914828 DOI: 10.1021/Ja075865S  0.722
2007 Tam A, Soellner MB, Raines RT. Water-soluble phosphinothiols for traceless staudinger ligation and integration with expressed protein ligation. Journal of the American Chemical Society. 129: 11421-30. PMID 17713909 DOI: 10.1021/Ja073204P  0.666
2007 Soellner MB, Rawls KA, Grundner C, Alber T, Ellman JA. Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB. Journal of the American Chemical Society. 129: 9613-5. PMID 17636914 DOI: 10.1021/Ja0727520  0.662
2006 Soellner MB, Tam A, Raines RT. Staudinger ligation of peptides at non-glycyl residues. The Journal of Organic Chemistry. 71: 9824-30. PMID 17168602 DOI: 10.1021/Jo0620056  0.686
2006 Soellner MB, Nilsson BL, Raines RT. Reaction mechanism and kinetics of the traceless Staudinger ligation. Journal of the American Chemical Society. 128: 8820-8. PMID 16819875 DOI: 10.1021/Ja060484K  0.641
2005 Nilsson BL, Soellner MB, Raines RT. Chemical synthesis of proteins. Annual Review of Biophysics and Biomolecular Structure. 34: 91-118. PMID 15869385 DOI: 10.1146/Annurev.Biophys.34.040204.144700  0.688
2005 Smith BD, Soellner MB, Raines RT. Synthetic surfaces for ribonuclease adsorption. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 187-90. PMID 15620301 DOI: 10.1021/La0480686  0.562
2003 Soellner MB, Dickson KA, Nilsson BL, Raines RT. Site-specific protein immobilization by Staudinger ligation. Journal of the American Chemical Society. 125: 11790-1. PMID 14505380 DOI: 10.1021/Ja036712H  0.743
2003 Nilsson BL, Hondal RJ, Soellner MB, Raines RT. Protein assembly by orthogonal chemical ligation methods. Journal of the American Chemical Society. 125: 5268-9. PMID 12720426 DOI: 10.1021/Ja029752E  0.75
2003 Smith BD, Soellner MB, Raines RT. Potent inhibition of ribonuclease A by oligo(vinylsulfonic acid). The Journal of Biological Chemistry. 278: 20934-8. PMID 12649287 DOI: 10.1074/Jbc.M301852200  0.616
2002 Soellner MB, Nilsson BL, Raines RT. Staudinger ligation of alpha-azido acids retains stereochemistry. The Journal of Organic Chemistry. 67: 4993-6. PMID 12098322 DOI: 10.1021/Jo025631L  0.686
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