| Year |
Citation |
Score |
| 2024 |
Liu Q, Zhang J, Guo C, Wang M, Wang C, Yan Y, Sun L, Wang D, Zhang L, Yu H, Hou L, Wu C, Zhu Y, Jiang G, Zhu H, ... ... Ding L, et al. Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies. Cell. 187: 184-203.e28. PMID 38181741 DOI: 10.1016/j.cell.2023.12.004 |
0.331 |
|
| 2023 |
Iglesia MD, Jayasinghe RG, Chen S, Terekhanova NV, Herndon JM, Storrs E, Karpova A, Zhou DC, Al Deen NN, Shinkle AT, Lu RJ, Caravan W, Houston A, Zhao Y, Sato K, ... ... Ding L, et al. Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages. Biorxiv : the Preprint Server For Biology. PMID 37961519 DOI: 10.1101/2023.10.31.565031 |
0.614 |
|
| 2023 |
Terekhanova NV, Karpova A, Liang WW, Strzalkowski A, Chen S, Li Y, Southard-Smith AN, Iglesia MD, Wendl MC, Jayasinghe RG, Liu J, Song Y, Cao S, Houston A, Liu X, ... ... Ding L, et al. Epigenetic regulation during cancer transitions across 11 tumour types. Nature. PMID 37914932 DOI: 10.1038/s41586-023-06682-5 |
0.624 |
|
| 2023 |
Liang WW, Lu RJ, Jayasinghe RG, Foltz SM, Porta-Pardo E, Geffen Y, Wendl MC, Lazcano R, Kolodziejczak I, Song Y, Govindan A, Demicco EG, Li X, Li Y, Sethuraman S, ... ... Ding L, et al. Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin. Cancer Cell. PMID 37582362 DOI: 10.1016/j.ccell.2023.07.013 |
0.608 |
|
| 2023 |
Geffen Y, Anand S, Akiyama Y, Yaron TM, Song Y, Johnson JL, Govindan A, Babur Ö, Li Y, Huntsman E, Wang LB, Birger C, Heiman DI, Zhang Q, Miller M, ... ... Ding L, et al. Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation. Cell. PMID 37582358 DOI: 10.1016/j.cell.2023.07.013 |
0.308 |
|
| 2023 |
Li Y, Porta-Pardo E, Tokheim C, Bailey MH, Yaron TM, Stathias V, Geffen Y, Imbach KJ, Cao S, Anand S, Akiyama Y, Liu W, Wyczalkowski MA, Song Y, Storrs EP, ... ... Ding L, et al. Pan-cancer proteogenomics connects oncogenic drivers to functional states. Cell. PMID 37582357 DOI: 10.1016/j.cell.2023.07.014 |
0.658 |
|
| 2023 |
Li Y, Dou Y, Da Veiga Leprevost F, Geffen Y, Calinawan AP, Aguet F, Akiyama Y, Anand S, Birger C, Cao S, Chaudhary R, Chilappagari P, Cieslik M, Colaprico A, Zhou DC, ... ... Ding L, et al. Proteogenomic data and resources for pan-cancer analysis. Cancer Cell. 41: 1397-1406. PMID 37582339 DOI: 10.1016/j.ccell.2023.06.009 |
0.343 |
|
| 2023 |
Wu Y, Terekhanova NV, Caravan W, Naser Al Deen N, Lal P, Chen S, Mo CK, Cao S, Li Y, Karpova A, Liu R, Zhao Y, Shinkle A, Strunilin I, Weimholt C, ... ... Ding L, et al. Author Correction: Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma. Nature Communications. 14: 2817. PMID 37198186 DOI: 10.1038/s41467-023-38561-y |
0.535 |
|
| 2023 |
Wu Y, Terekhanova NV, Caravan W, Naser Al Deen N, Lal P, Chen S, Mo CK, Cao S, Li Y, Karpova A, Liu R, Zhao Y, Shinkle A, Strunilin I, Weimholt C, ... ... Ding L, et al. Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma. Nature Communications. 14: 1681. PMID 36973268 DOI: 10.1038/s41467-023-37211-7 |
0.622 |
|
| 2023 |
Yao L, Wang JT, Jayasinghe RG, O'Neal J, Tsai CF, Rettig MP, Song Y, Liu R, Zhao Y, Ibrahim OM, Fiala MA, Fortier JM, Chen S, Gehrs L, Martins Rodrigues F, ... ... Ding L, et al. Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma. Cancer Research. PMID 36779841 DOI: 10.1158/0008-5472.CAN-22-1769 |
0.623 |
|
| 2022 |
Yao L, Jayasinghe RG, Lee BH, Bhasin SS, Pilcher W, Doxie DB, Gonzalez-Kozlova E, Dasari S, Fiala MA, Pita-Juarez Y, Strausbauch M, Kelly G, Thomas BE, Kumar SK, Cho HJ, ... ... Ding L, et al. Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis. Cancer Research Communications. 2: 1255-1265. PMID 36969740 DOI: 10.1158/2767-9764.CRC-22-0022 |
0.571 |
|
| 2022 |
Li Y, Lih TM, Dhanasekaran SM, Mannan R, Chen L, Cieslik M, Wu Y, Lu RJ, Clark DJ, Kołodziejczak I, Hong R, Chen S, Zhao Y, Chugh S, Caravan W, ... ... Ding L, et al. Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness. Cancer Cell. PMID 36563681 DOI: 10.1016/j.ccell.2022.12.001 |
0.617 |
|
| 2022 |
Li QK, Hu Y, Chen L, Schnaubelt M, Cui Zhou D, Li Y, Lu RJ, Thiagarajan M, Hostetter G, Newton CJ, Jewell SD, Omenn G, Robles AI, Mesri M, Bathe OF, ... ... Ding L, et al. Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma. Clinical Proteomics. 19: 36. PMID 36266629 DOI: 10.1186/s12014-022-09373-x |
0.325 |
|
| 2022 |
Cui Zhou D, Jayasinghe RG, Chen S, Herndon JM, Iglesia MD, Navale P, Wendl MC, Caravan W, Sato K, Storrs E, Mo CK, Liu J, Southard-Smith AN, Wu Y, Naser Al Deen N, ... ... Ding L, et al. Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer. Nature Genetics. PMID 35995947 DOI: 10.1038/s41588-022-01157-1 |
0.602 |
|
| 2022 |
Storrs EP, Zhou DC, Wendl MC, Wyczalkowski MA, Karpova A, Wang LB, Li Y, Southard-Smith A, Jayasinghe RG, Yao L, Liu R, Wu Y, Terekhanova NV, Zhu H, Herndon JM, ... ... Ding L, et al. Pollock: fishing for cell states. Bioinformatics Advances. 2: vbac028. PMID 35603231 DOI: 10.1093/bioadv/vbac028 |
0.569 |
|
| 2022 |
Mani DR, Krug K, Zhang B, Satpathy S, Clauser KR, Ding L, Ellis M, Gillette MA, Carr SA. Cancer proteogenomics: current impact and future prospects. Nature Reviews. Cancer. PMID 35236940 DOI: 10.1038/s41568-022-00446-5 |
0.356 |
|
| 2022 |
Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA, Patidar R, Chen L, Wyczalkowski MA, ... ... Ding L, et al. Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nature Communications. 13: 294. PMID 34996889 DOI: 10.1038/s41467-021-27678-7 |
0.531 |
|
| 2021 |
Chen F, Wendl MC, Wyczalkowski MA, Bailey MH, Li Y, Ding L. Moving pan-cancer studies from basic research toward the clinic. Nature Cancer. 2: 879-890. PMID 35121865 DOI: 10.1038/s43018-021-00250-4 |
0.653 |
|
| 2021 |
Qing T, Wang X, Jun T, Ding L, Pusztai L, Huang K. Genomic Determinants of Homologous Recombination Deficiency across Human Cancers. Cancers. 13. PMID 34572800 DOI: 10.3390/cancers13184572 |
0.429 |
|
| 2021 |
Cao L, Huang C, Cui Zhou D, Hu Y, Lih TM, Savage SR, Krug K, Clark DJ, Schnaubelt M, Chen L, da Veiga Leprevost F, Eguez RV, Yang W, Pan J, Wen B, ... ... Ding L, et al. Proteogenomic characterization of pancreatic ductal adenocarcinoma. Cell. 184: 5031-5052.e26. PMID 34534465 DOI: 10.1016/j.cell.2021.08.023 |
0.305 |
|
| 2021 |
Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA, Patidar R, Chen L, Wyczalkowski MA, ... ... Ding L, et al. Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment. Nature Communications. 12: 5086. PMID 34429404 DOI: 10.1038/s41467-021-25177-3 |
0.657 |
|
| 2021 |
Liu R, Gao Q, Foltz SM, Fowles JS, Yao L, Wang JT, Cao S, Sun H, Wendl MC, Sethuraman S, Weerasinghe A, Rettig MP, Storrs EP, Yoon CJ, Wyczalkowski MA, ... ... Ding L, et al. Co-evolution of tumor and immune cells during progression of multiple myeloma. Nature Communications. 12: 2559. PMID 33963182 DOI: 10.1038/s41467-021-22804-x |
0.571 |
|
| 2021 |
Huang KL, Scott AD, Zhou DC, Wang LB, Weerasinghe A, Elmas A, Liu R, Wu Y, Wendl MC, Wyczalkowski MA, Baral J, Sengupta S, Lai CW, Ruggles K, Payne SH, ... ... Ding L, et al. Spatially interacting phosphorylation sites and mutations in cancer. Nature Communications. 12: 2313. PMID 33875650 DOI: 10.1038/s41467-021-22481-w |
0.73 |
|
| 2021 |
Dong G, Wendl MC, Zhang B, Ding L, Huang KL. AeQTL: eQTL analysis using region-based aggregation of rare genomic variants. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 26: 172-183. PMID 33691015 |
0.656 |
|
| 2021 |
Wang LB, Karpova A, Gritsenko MA, Kyle JE, Cao S, Li Y, Rykunov D, Colaprico A, Rothstein JH, Hong R, Stathias V, Cornwell M, Petralia F, Wu Y, Reva B, ... ... Ding L, et al. Proteogenomic and metabolomic characterization of human glioblastoma. Cancer Cell. PMID 33577785 DOI: 10.1016/j.ccell.2021.01.006 |
0.633 |
|
| 2021 |
Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, ... ... Ding L, et al. Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. Cell Reports. 34: 108707. PMID 33535033 DOI: 10.1016/j.celrep.2021.108707 |
0.317 |
|
| 2021 |
Han X, Zhang S, Zhou DC, Wang D, He X, Yuan D, Li R, He J, Duan X, Wendl MC, Ding L, Niu B. MSIsensor-ct: microsatellite instability detection using cfDNA sequencing data. Briefings in Bioinformatics. PMID 33461213 DOI: 10.1093/bib/bbaa402 |
0.594 |
|
| 2021 |
Huang C, Chen L, Savage SR, Eguez RV, Dou Y, Li Y, da Veiga Leprevost F, Jaehnig EJ, Lei JT, Wen B, Schnaubelt M, Krug K, Song X, Cieślik M, Chang HY, ... ... Ding L, et al. Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma. Cancer Cell. PMID 33417831 DOI: 10.1016/j.ccell.2020.12.007 |
0.585 |
|
| 2020 |
Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S, Li Y, Kelso S, Saksena G, Ellrott K, Wendl MC, ... ... Ding L, et al. Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature Communications. 11: 6232. PMID 33257764 DOI: 10.1038/s41467-020-20128-w |
0.647 |
|
| 2020 |
Petralia F, Tignor N, Reva B, Koptyra M, Chowdhury S, Rykunov D, Krek A, Ma W, Zhu Y, Ji J, Calinawan A, Whiteaker JR, Colaprico A, Stathias V, Omelchenko T, ... ... Ding L, et al. Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer. Cell. PMID 33242424 DOI: 10.1016/j.cell.2020.10.044 |
0.319 |
|
| 2020 |
Cao S, Zhou DC, Oh C, Jayasinghe RG, Zhao Y, Yoon CJ, Wyczalkowski MA, Bailey MH, Tsou T, Gao Q, Malone A, Reynolds S, Shmulevich I, Wendl MC, Chen F, ... Ding L, et al. Discovery of driver non-coding splice-site-creating mutations in cancer. Nature Communications. 11: 5573. PMID 33149122 DOI: 10.1038/s41467-020-19307-6 |
0.631 |
|
| 2020 |
Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S, Kelso S, Saksena G, Ellrott K, Wendl MC, Wheeler DA, ... ... Ding L, et al. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature Communications. 11: 4748. PMID 32958763 DOI: 10.1038/S41467-020-18151-Y |
0.712 |
|
| 2020 |
Lu X, Wang X, Ding L, Li J, Gao Y, He K. frDriver: A functional region driver identification for protein sequence. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 32870797 DOI: 10.1109/TCBB.2020.3020096 |
0.368 |
|
| 2020 |
Gillette MA, Satpathy S, Cao S, Dhanasekaran SM, Vasaikar SV, Krug K, Petralia F, Li Y, Liang WW, Reva B, Krek A, Ji J, Song X, Liu W, Hong R, ... ... Ding L, et al. Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma. Cell. 182: 200-225.e35. PMID 32649874 DOI: 10.1016/J.Cell.2020.06.013 |
0.651 |
|
| 2020 |
Foltz SM, Gao Q, Yoon CJ, Sun H, Yao L, Li Y, Jayasinghe RG, Cao S, King J, Kohnen DR, Fiala MA, Ding L, Vij R. Evolution and structure of clinically relevant gene fusions in multiple myeloma. Nature Communications. 11: 2666. PMID 32471990 DOI: 10.1038/S41467-020-16434-Y |
0.352 |
|
| 2020 |
Oak N, Cherniack AD, Mashl RJ, Hirsch FR, Ding L, Beroukhim R, Gümüş ZH, Plon SE, Huang KL. Ancestry-specific predisposing germline variants in cancer. Genome Medicine. 12: 51. PMID 32471518 DOI: 10.1186/S13073-020-00744-3 |
0.391 |
|
| 2020 |
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, et al. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell. 181: 236-249. PMID 32302568 DOI: 10.1016/J.Cell.2020.03.053 |
0.437 |
|
| 2020 |
Dou Y, Kawaler EA, Cui Zhou D, Gritsenko MA, Huang C, Blumenberg L, Karpova A, Petyuk VA, Savage SR, Satpathy S, Liu W, Wu Y, Tsai CF, Wen B, Li Z, ... ... Ding L, et al. Proteogenomic Characterization of Endometrial Carcinoma. Cell. PMID 32059776 DOI: 10.1016/J.Cell.2020.01.026 |
0.408 |
|
| 2020 |
Gillette M, Krug K, Satpathy S, Jaehnig E, Karpova A, Clauser K, Tang L, Blumenberg L, Kothadia R, Ruggles K, Zhang B, Ding L, Mertins P, Mani, Ellis M, et al. Abstract TS1-2: Proteogenomic Landscape of Prospectively Collected Breast Cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Ts1-2 |
0.418 |
|
| 2020 |
Kawaler EA, Dou Y, Zhou DC, Gritsenko MA, Rodland KD, Ding L, Zhang B, Liu T, Fenyö D. Abstract 6580: Proteogenomic characterization of endometrial carcinoma Cancer Research. 80: 6580-6580. DOI: 10.1158/1538-7445.Am2020-6580 |
0.517 |
|
| 2020 |
Petralia F, Tignor N, Reva B, Raman P, Chowdhury S, Rykunov D, Krek A, Ma W, Ji J, Song X, Zhu Y, Rokita JL, Colaprico A, Calinawan A, Whiteaker JR, ... ... Ding L, et al. Abstract 445: Integrated proteogenomic characterization across seven histological types of pediatric brain tumors Cancer Research. 80: 445-445. DOI: 10.1158/1538-7445.Am2020-445 |
0.349 |
|
| 2020 |
Woo XY, Giordano J, Srivastava A, Zhao Z, Lloyd MW, Bruijn Rd, Suh Y, Kim J, Yang H, Lee C, Dean DA, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, ... ... Ding L, et al. Abstract 1673: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts Cancer Research. 80: 1673-1673. DOI: 10.1158/1538-7445.Am2020-1673 |
0.426 |
|
| 2019 |
Clark DJ, Dhanasekaran SM, Petralia F, Pan J, Song X, Hu Y, da Veiga Leprevost F, Reva B, Lih TM, Chang HY, Ma W, Huang C, Ricketts CJ, Chen L, Krek A, ... ... Ding L, et al. Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. Cell. 179: 964-983.e31. PMID 31675502 DOI: 10.1016/J.Cell.2019.10.007 |
0.385 |
|
| 2019 |
Gao Q, Zhu H, Dong L, Shi W, Chen R, Song Z, Huang C, Li J, Dong X, Zhou Y, Liu Q, Ma L, Wang X, Zhou J, Liu Y, ... ... Ding L, et al. Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell. 179: 561-577.e22. PMID 31585088 DOI: 10.1016/J.Cell.2019.08.052 |
0.303 |
|
| 2019 |
Gao GF, Parker JS, Reynolds SM, Silva TC, Wang LB, Zhou W, Akbani R, Bailey M, Balu S, Berman BP, Brooks D, Chen H, Cherniack AD, Demchok JA, Ding L, et al. Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data. Cell Systems. 9: 24-34.e10. PMID 31344359 DOI: 10.1016/J.Cels.2019.06.006 |
0.391 |
|
| 2019 |
Huang KL, Wu Y, Primeau T, Wang YT, Gao Y, McMichael JF, Scott AD, Cao S, Wendl MC, Johnson KJ, Ruggles K, Held J, Payne SH, Davies SR, Dar A, ... ... Ding L, et al. Regulated Phosphosignaling Associated with Breast Cancer Subtypes and Druggability. Molecular & Cellular Proteomics : McP. PMID 31196969 DOI: 10.1074/Mcp.Ra118.001243 |
0.717 |
|
| 2019 |
Vasaikar S, Huang C, Wang X, Petyuk VA, Savage SR, Wen B, Dou Y, Zhang Y, Shi Z, Arshad OA, Gritsenko MA, Zimmerman LJ, McDermott JE, Clauss TR, Moore RJ, ... ... Ding L, et al. Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities. Cell. PMID 31031003 DOI: 10.1016/J.Cell.2019.03.030 |
0.451 |
|
| 2019 |
Chaisson MJP, Sanders AD, Zhao X, Malhotra A, Porubsky D, Rausch T, Gardner EJ, Rodriguez OL, Guo L, Collins RL, Fan X, Wen J, Handsaker RE, Fairley S, Kronenberg ZN, ... ... Ding L, et al. Multi-platform discovery of haplotype-resolved structural variation in human genomes. Nature Communications. 10: 1784. PMID 30992455 DOI: 10.1038/S41467-018-08148-Z |
0.382 |
|
| 2019 |
Wang F, Zhang S, Kim TB, Lin YY, Iqbal R, Wang Z, Mohanty V, Sircar K, Karam JA, Wendl MC, Meric-Bernstam F, Weinstein JN, Ding L, Mills GB, Chen K. Integrated transcriptomic-genomic tool Texomer profiles cancer tissues. Nature Methods. PMID 30988467 DOI: 10.1038/S41592-019-0388-9 |
0.66 |
|
| 2019 |
Adamovich AI, Banerjee T, Wingo M, Duncan K, Ning J, Martins Rodrigues F, Huang KL, Lee C, Chen F, Ding L, Parvin JD. Functional analysis of BARD1 missense variants in homology-directed repair and damage sensitivity. Plos Genetics. 15: e1008049. PMID 30925164 DOI: 10.1371/Journal.Pgen.1008049 |
0.405 |
|
| 2019 |
Wang T, Sun H, Cui Zhou D, Liu R, Yao L, Fiala MA, Kohnen DR, O'Neal J, Rettig MP, Fowles JS, Oh ST, Jayasinghe RG, Vij R, DiPersio JF, Ding L. Single-Cell Pathway Enrichment and Regulatory Profiling of Multiple Myeloma across Disease Stages Blood. 134: 364-364. DOI: 10.1182/Blood-2019-131361 |
0.38 |
|
| 2019 |
Jayasinghe RG, Wu Y, Zhu Y, Liu R, Fiala MA, Kohnen DR, Tsai C, Mani S, King J, Rettig MP, O'Neal J, Wang T, Foltz SM, Yao L, Sun H, ... ... Ding L, et al. Single-Cell Transcriptomic and Proteomic Diversity in Multiple Myeloma Blood. 134: 5531-5531. DOI: 10.1182/Blood-2019-131005 |
0.311 |
|
| 2019 |
Cho KC, Hruban R, Zhang H, Huang C, Zhang B, Zhou DC, Ding L, Boja E. Abstract A60: Integrated proteogenomic characterization of pancreatic ductal adenocarcinoma Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A60 |
0.475 |
|
| 2019 |
Zhang B, Vasaikar S, Huang C, Wang X, Petyuk VA, Savage SR, Wen B, Dou Y, Zhang Y, Shi Z, Arshad OA, Gritsenko MA, Zimmerman LJ, McDermott JE, Clauss TR, ... ... Ding L, et al. Abstract LB-006: Proteogenomic characterization of human colon cancer reveals new therapeutic opportunities Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-006 |
0.477 |
|
| 2018 |
Sun SQ, Mashl RJ, Sengupta S, Scott AD, Wang W, Batra P, Wang LB, Wyczalkowski MA, Ding L. Database of evidence for precision oncology portal. Bioinformatics (Oxford, England). 34: 4315-4317. PMID 30535306 DOI: 10.1093/Bioinformatics/Bty531 |
0.656 |
|
| 2018 |
Scott AD, Huang KL, Weerasinghe A, Mashl RJ, Gao Q, Martins Rodrigues F, Wyczalkowski M, Ding L. CharGer: Clinical Characterization of Germline Variants. Bioinformatics (Oxford, England). PMID 30102335 DOI: 10.1093/Bioinformatics/Bty649 |
0.583 |
|
| 2018 |
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, ... ... Ding L, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 174: 1034-1035. PMID 30096302 DOI: 10.1016/J.Cell.2018.07.034 |
0.69 |
|
| 2018 |
Sengupta S, Sun SQ, Huang KL, Oh C, Bailey MH, Varghese R, Wyczalkowski MA, Ning J, Tripathi P, McMichael JF, Johnson KJ, Kandoth C, Welch J, Ma C, Wendl MC, ... ... Ding L, et al. Integrative omics analyses broaden treatment targets in human cancer. Genome Medicine. 10: 60. PMID 30053901 DOI: 10.1186/S13073-018-0564-Z |
0.657 |
|
| 2018 |
Alberti MO, Srivatsan SN, Shao J, McNulty SN, Chang GS, Miller CA, Dunlap JB, Yang F, Press RD, Gao Q, Ding L, Heusel JW, Duncavage EJ, Walter MJ. Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS. Leukemia. PMID 29959414 DOI: 10.1038/S41375-018-0193-Y |
0.348 |
|
| 2018 |
Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, ... ... Ding L, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 173: 371-385.e18. PMID 29625053 DOI: 10.1016/J.Cell.2018.02.060 |
0.714 |
|
| 2018 |
Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, ... ... Ding L, et al. Pathogenic Germline Variants in 10,389 Adult Cancers. Cell. 173: 355-370.e14. PMID 29625052 DOI: 10.1016/J.Cell.2018.03.039 |
0.775 |
|
| 2018 |
Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, ... ... Ding L, et al. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 173: 321-337.e10. PMID 29625050 DOI: 10.1016/J.Cell.2018.03.035 |
0.433 |
|
| 2018 |
Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortés-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, et al. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell. 173: 305-320.e10. PMID 29625049 DOI: 10.1016/J.Cell.2018.03.033 |
0.695 |
|
| 2018 |
Jayasinghe RG, Cao S, Gao Q, Wendl MC, Vo NS, Reynolds SM, Zhao Y, Climente-González H, Chai S, Wang F, Varghese R, Huang M, Liang WW, Wyczalkowski MA, Sengupta S, ... ... Ding L, et al. Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports. 23: 270-281.e3. PMID 29617666 DOI: 10.1016/J.Celrep.2018.03.052 |
0.684 |
|
| 2018 |
Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, ... ... Ding L, et al. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports. 23: 239-254.e6. PMID 29617664 DOI: 10.1016/J.Celrep.2018.03.076 |
0.483 |
|
| 2018 |
Gao Q, Liang WW, Foltz SM, Mutharasu G, Jayasinghe RG, Cao S, Liao WW, Reynolds SM, Wyczalkowski MA, Yao L, Yu L, Sun SQ, Chen K, ... ... Ding L, et al. Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Reports. 23: 227-238.e3. PMID 29617662 DOI: 10.1016/J.Celrep.2018.03.050 |
0.671 |
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| 2018 |
Ellrott K, Bailey MH, Saksena G, Covington KR, Kandoth C, Stewart C, Hess J, Ma S, Chiotti KE, McLellan M, Sofia HJ, Hutter C, Getz G, Wheeler D, Ding L, et al. Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems. 6: 271-281.e7. PMID 29596782 DOI: 10.1016/J.Cels.2018.03.002 |
0.504 |
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| 2018 |
Ng PK, Li J, Jeong KJ, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, ... ... Ding L, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 33: 450-462.e10. PMID 29533785 DOI: 10.1016/J.Ccell.2018.01.021 |
0.486 |
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| 2018 |
Cao Y, Zhou W, Li L, Wang J, Gao Z, Jiang Y, Jiang X, Shan A, Bailey MH, Huang KL, Sun SQ, McLellan MD, Niu B, Wang W, Ding L, et al. Pan-cancer analysis of somatic mutations across 21 neuroendocrine tumor types. Cell Research. PMID 29507395 DOI: 10.1038/S41422-018-0019-5 |
0.461 |
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| 2018 |
Mundt F, Rajput S, Li S, Ruggles KV, Mooradian AD, Mertins P, Gillette MA, Krug K, Guo Z, Hoog J, Erdmann-Gilmore P, Primeau T, Huang S, Edwards DP, Wang X, ... ... Ding L, et al. Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers. Cancer Research. PMID 29472518 DOI: 10.1158/0008-5472.Can-17-1990 |
0.305 |
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| 2018 |
Martins Rodrigues F, Gao Q, Huang K, Scott AD, Foltz SM, King J, Fiala MA, Kohnen DR, DiPersio JF, Vij R, Ding L. Characterization of Germline Variants in Multiple Myeloma Blood. 132: 4499-4499. DOI: 10.1182/Blood-2018-99-118673 |
0.683 |
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| 2018 |
Foltz SM, Gao Q, Yoon CJ, Weerasinghe A, Sun H, Yao L, Fiala MA, Kohnen DR, King J, Ju YS, DiPersio JF, Vij R, Ding L. Comprehensive Multi-Omics Analysis of Gene Fusions in a Large Multiple Myeloma Cohort Blood. 132: 1898-1898. DOI: 10.1182/Blood-2018-99-117245 |
0.373 |
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| 2018 |
Wyczalkowski MA, Bailey MH, Lou C, Hu F, Chen JY, Batra P, McLellan MD, Ding L, Wendl MC. Abstract B11: The MuSiC2 system for discovery and visualization of coding and noncoding cancer drivers Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-B11 |
0.688 |
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| 2018 |
Ellrott K, Bailey M, Saksena G, Covington K, Kandoth C, Stewart C, McLellan M, Sofia H, Hutter C, Getz G, Wheeler D, Ding L. Abstract 926: Multi-Center Mutation Calling in Multiple Cancers: The MC3 Project Cancer Research. 78: 926-926. DOI: 10.1158/1538-7445.Am2018-926 |
0.451 |
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| 2018 |
Bailey MH, Wang L, Liang W, Foltz S, Dong G, Wendl MC, McLellan M, Hirbe AC, Simpson J, Gerstein M, Ding L. Abstract 419: Reproducibility assessment of mutations calls in exome- and whole-genome sequencing using consensus calling from TCGA and ICGC Cancer Research. 78: 419-419. DOI: 10.1158/1538-7445.Am2018-419 |
0.716 |
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| 2018 |
Bailey MH, Zhou DC, Wu Y, Wyczalkowski MA, Wang L, Rodrigues FM, Mills G, Payne S, Fenyo D, Ding L. Abstract 2706: Effects of germline and somatic mutations on protein expression in tumor and adjacent normal tissues in breast, ovarian, and colorectal tumors Cancer Research. 78: 2706-2706. DOI: 10.1158/1538-7445.Am2018-2706 |
0.456 |
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| 2018 |
Jayasinghe RG, Cao S, Gao Q, Wyczalkowski MA, Sengupta S, Walter MJ, Maher C, Wendl MC, Chen F, Eyras E, Lazar AJ, Chen K, Shmulevich I, Ding L. Abstract 2362: Comprehensive portrait of canonical and non-canonical splicing in cancer Cancer Research. 78: 2362-2362. DOI: 10.1158/1538-7445.Am2018-2362 |
0.702 |
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| 2017 |
Foltz S, Liang WW, Xie M, Ding L. MIRMMR: binary classification of microsatellite instability using methylation and mutations. Bioinformatics (Oxford, England). PMID 28961932 DOI: 10.1093/Bioinformatics/Btx507 |
0.404 |
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| 2017 |
Wang X, Mooradian AD, Erdmann-Gilmore P, Zhang Q, Viner R, Davies SR, Huang KL, Bomgarden R, Van Tine BA, Shao J, Ding L, Li S, Ellis MJ, Rogers JC, Townsend RR, et al. Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner. Science Signaling. 10. PMID 28790197 DOI: 10.1126/Scisignal.Aam8065 |
0.351 |
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| 2017 |
Niu B, Scott AD, Sengupta S, Bailey MH, Batra P, Ning J, Wyczalkowski MA, Liang WW, Zhang Q, D McLellan M, Sun SQ, Tripathi P, Lou C, Ye K, Jay Mashl R, ... ... Ding L, et al. Corrigendum: Protein-structure-guided discovery of functional mutations across 19 cancer types. Nature Genetics. 49: 1286. PMID 28747753 DOI: 10.1038/Ng0817-1286A |
0.611 |
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| 2017 |
Wyczalkowski MA, Wylie KM, Cao S, McLellan MD, Flynn J, Huang M, Ye K, Fan X, Chen K, Wendl MC, Ding L. BreakPoint Surveyor: A Pipeline for Structural Variant Visualization. Bioinformatics (Oxford, England). PMID 28582538 DOI: 10.1093/Bioinformatics/Btx362 |
0.623 |
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| 2017 |
Mashl RJ, Scott AD, Huang KL, Wyczalkowski MA, Yoon CJ, Niu B, DeNardo E, Yellapantula VD, Handsaker RE, Chen K, Koboldt DC, Ye K, Fenyö D, Raphael B, Wendl MC, ... Ding L, et al. GenomeVIP: a cloud platform for genomic variant discovery and interpretation. Genome Research. PMID 28522612 DOI: 10.1101/Gr.211656.116 |
0.731 |
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| 2017 |
Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR, Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, ... ... Ding L, et al. Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nature Communications. 8: 15479. PMID 28440318 DOI: 10.1038/Ncomms15479 |
0.709 |
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| 2017 |
Huang KL, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, Mani DR, Clauser KR, Tanioka M, Usary J, Kavuri SM, Xie L, Yoon C, Qiao JW, Wrobel J, ... ... Ding L, et al. Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nature Communications. 8: 14864. PMID 28348404 DOI: 10.1038/Ncomms14864 |
0.742 |
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| 2017 |
Marshall AD, Bailey CG, Champ K, Vellozzi M, O'Young P, Metierre C, Feng Y, Thoeng A, Richards AM, Schmitz U, Biro M, Jayasinghe R, Ding L, Anderson L, Mardis ER, et al. CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic. Oncogene. PMID 28319062 DOI: 10.1038/Onc.2017.25 |
0.474 |
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| 2017 |
Hoadley KA, Siegel MB, Kanchi KL, Miller CA, Ding L, Zhao W, He X, Parker JS, Wendl MC, Fulton RS, Demeter RT, Wilson RK, Carey LA, Perou CM, Mardis ER. Correction: Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases. Plos Medicine. 14: e1002222. PMID 28068332 DOI: 10.1371/journal.pmed.1002222 |
0.618 |
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| 2016 |
Troester MA, Hoadley KA, D'Arcy M, Cherniack AD, Stewart C, Koboldt DC, Robertson AG, Mahurkar S, Shen H, Wilkerson MD, Sandhu R, Johnson NB, Allison KH, Beck AH, Yau C, ... ... Ding L, et al. DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas. Npj Breast Cancer. 2: 16007. PMID 28721375 DOI: 10.1038/npjbcancer.2016.7 |
0.319 |
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| 2016 |
Hoadley KA, Siegel MB, Kanchi KL, Miller CA, Ding L, Zhao W, He X, Parker JS, Wendl MC, Fulton RS, Demeter RT, Wilson RK, Carey LA, Perou CM, Mardis ER. Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases. Plos Medicine. 13: e1002174. PMID 27923045 DOI: 10.1371/Journal.Pmed.1002174 |
0.648 |
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| 2016 |
Chong Z, Ruan J, Gao M, Zhou W, Chen T, Fan X, Ding L, Lee AY, Boutros P, Chen J, Chen K. novoBreak: local assembly for breakpoint detection in cancer genomes. Nature Methods. PMID 27892959 DOI: 10.1038/Nmeth.4084 |
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| 2016 |
Miller CA, McMichael J, Dang HX, Maher CA, Ding L, Ley TJ, Mardis ER, Wilson RK. Visualizing tumor evolution with the fishplot package for R. Bmc Genomics. 17: 880. PMID 27821060 DOI: 10.1186/S12864-016-3195-Z |
0.304 |
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| 2016 |
Faber ZJ, Chen X, Gedman AL, Boggs K, Cheng J, Ma J, Radtke I, Chao JR, Walsh MP, Song G, Andersson AK, Dang J, Dong L, Liu Y, Huether R, ... ... Ding L, et al. The genomic landscape of core-binding factor acute myeloid leukemias. Nature Genetics. PMID 27798625 DOI: 10.1038/Ng.3709 |
0.428 |
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| 2016 |
Cao S, Wendl MC, Wyczalkowski MA, Wylie K, Ye K, Jayasinghe R, Xie M, Wu S, Niu B, Grubb R, Johnson KJ, Gay H, Chen K, Rader JS, Dipersio JF, ... ... Ding L, et al. Divergent viral presentation among human tumors and adjacent normal tissues. Scientific Reports. 6: 28294. PMID 27339696 DOI: 10.1038/Srep28294 |
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| 2016 |
Niu B, Scott AD, Sengupta S, Bailey MH, Batra P, Ning J, Wyczalkowski MA, Liang WW, Zhang Q, McLellan MD, Sun SQ, Tripathi P, Lou C, Ye K, Mashl RJ, ... ... Ding L, et al. Protein-structure-guided discovery of functional mutations across 19 cancer types. Nature Genetics. PMID 27294619 DOI: 10.1038/Ng.3586 |
0.766 |
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| 2016 |
Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, ... ... Ding L, et al. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 534: 55-62. PMID 27251275 DOI: 10.1038/Nature18003 |
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| 2016 |
Sung H, Kanchi KL, Wang X, Hill KS, Messina JL, Lee JH, Kim Y, Dees ND, Ding L, Teer JK, Yang S, Sarnaik AA, Sondak VK, Mulé JJ, Wilson RK, et al. Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation. Oncotarget. PMID 26993606 DOI: 10.18632/Oncotarget.8127 |
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| 2016 |
Shen W, Zhao GQ, Liang Z, Yellapantula V, Sun S, Tang LFP, Lin S, Ying K, Fields RC, Ding L. Retrospective analysis of circulating tumor DNA of archived plasma samples. Journal of Clinical Oncology. 34: e23175-e23175. DOI: 10.1200/Jco.2016.34.15_Suppl.E23175 |
0.356 |
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| 2016 |
Scott AD, Yellapantula VD, Yoon CJ, Wendl M, Tomasson MH, Fiala MA, DiPersio JF, Vij R, Ding L. Uncovering Clonal and Subclonal Druggable Targets in Multiple Myeloma Using Omic Data Blood. 128: 2084-2084. DOI: 10.1182/Blood.V128.22.2084.2084 |
0.759 |
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| 2016 |
Mertins P, Mani, Ruggles K, Gillette M, Clauser K, Wang P, Wang X, Qiao J, Cao S, Petralia F, Mundt F, Tu Z, Lei J, Gatza M, Wilkerson M, ... ... Ding L, et al. Abstract IA29: Proteogenomic and phosphoproteomic analysis of breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-Ia29 |
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| 2016 |
Wang X, Erdmann-Gilmore P, Viner R, Meyer M, Stuhlmiller T, Davies S, Li S, Zhang Q, Mooradian A, Huang K, Bomgarden R, Ding L, Ellis M, Rogers J, Johnson G, et al. Abstract LB-267: The proteomic landscape of patient-derived breast cancer xenografts reveals tumor-specific differences in the breast tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-267 |
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| 2016 |
Hill KS, Sung H, Kanchi KL, Messina JL, Lee J, Kim Y, Ding L, Wilson RK, Weber JS, Kim M. Abstract 1863: Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation Cancer Research. 76: 1863-1863. DOI: 10.1158/1538-7445.Am2016-1863 |
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| 2015 |
Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, ... ... Ding L, et al. Patterns and functional implications of rare germline variants across 12 cancer types. Nature Communications. 6: 10086. PMID 26689913 DOI: 10.1038/Ncomms10086 |
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| 2015 |
Ye K, Wang J, Jayasinghe R, Lameijer EW, McMichael JF, Ning J, McLellan MD, Xie M, Cao S, Yellapantula V, Huang KL, Scott A, Foltz S, Niu B, Johnson KJ, ... ... Ding L, et al. Systematic discovery of complex insertions and deletions in human cancers. Nature Medicine. PMID 26657142 DOI: 10.1038/Nm.4002 |
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| 2015 |
Griffith M, Miller CA, Griffith OL, Krysiak K, Skidmore ZL, Ramu A, Walker JR, Dang HX, Trani L, Larson DE, Demeter RT, Wendl MC, McMichael JF, Austin RE, Magrini V, ... ... Ding L, et al. Optimizing cancer genome sequencing and analysis. Cell Systems. 1: 210-223. PMID 26645048 DOI: 10.7490/F1000Research.1110088.1 |
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| 2015 |
Ruggles KV, Tang Z, Wang X, Grover H, Askenazi M, Teubl J, Cao S, McLellan MD, Clauser KR, Tabb DL, Mertins P, Slebos R, Erdmann-Gilmore P, Li S, Gunawardena HP, ... ... Ding L, et al. An analysis of the sensitivity of proteogenomic mapping of somatic mutations and novel splicing events in cancer. Molecular & Cellular Proteomics : McP. PMID 26631509 DOI: 10.1074/Mcp.M115.056226 |
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| 2015 |
Zhang J, Walsh MF, Wu G, Edmonson MN, Gruber TA, Easton J, Hedges D, Ma X, Zhou X, Yergeau DA, Wilkinson MR, Vadodaria B, Chen X, McGee RB, Hines-Dowell S, ... ... Ding L, et al. Germline Mutations in Predisposition Genes in Pediatric Cancer. The New England Journal of Medicine. PMID 26580448 DOI: 10.1056/Nejmoa1508054 |
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| 2015 |
Muñoz JF, Gauthier GM, Desjardins CA, Gallo JE, Holder J, Sullivan TD, Marty AJ, Carmen JC, Chen Z, Ding L, Gujja S, Magrini V, Misas E, Mitreva M, Priest M, et al. The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia. Plos Genetics. 11: e1005493. PMID 26439490 DOI: 10.1371/Journal.Pgen.1005493 |
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| 2015 |
Sudmant PH, Rausch T, Gardner EJ, Handsaker RE, Abyzov A, Huddleston J, Zhang Y, Ye K, Jun G, Hsi-Yang Fritz M, Konkel MK, Malhotra A, Stütz AM, Shi X, Paolo Casale F, ... ... Ding L, et al. An integrated map of structural variation in 2,504 human genomes. Nature. 526: 75-81. PMID 26432246 DOI: 10.1038/Nature15394 |
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| 2015 |
Liu Y, Yasukawa M, Chen K, Hu L, Broaddus RR, Ding L, Mardis ER, Spellman P, Levine DA, Mills GB, Shmulevich I, Sood AK, Zhang W. Association of Somatic Mutations of ADAMTS Genes With Chemotherapy Sensitivity and Survival in High-Grade Serous Ovarian Carcinoma. Jama Oncology. 1: 486-94. PMID 26181259 DOI: 10.1001/Jamaoncol.2015.1432 |
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| 2015 |
Griffith M, Griffith OL, Smith SM, Ramu A, Callaway MB, Brummett AM, Kiwala MJ, Coffman AC, Regier AA, Oberkfell BJ, Sanderson GE, Mooney TP, Nutter NG, Belter EA, Du F, ... ... Ding L, et al. Genome Modeling System: A Knowledge Management Platform for Genomics. Plos Computational Biology. 11: e1004274. PMID 26158448 DOI: 10.1371/Journal.Pcbi.1004274 |
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Andersson AK, Ma J, Wang J, Chen X, Gedman AL, Dang J, Nakitandwe J, Holmfeldt L, Parker M, Easton J, Huether R, Kriwacki R, Rusch M, Wu G, Li Y, ... ... Ding L, et al. The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias. Nature Genetics. 47: 330-7. PMID 25730765 DOI: 10.1038/Ng.3230 |
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| 2015 |
Leiserson MD, Vandin F, Wu HT, Dobson JR, Eldridge JV, Thomas JL, Papoutsaki A, Kim Y, Niu B, McLellan M, Lawrence MS, Gonzalez-Perez A, Tamborero D, Cheng Y, Ryslik GA, ... ... Ding L, et al. Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes. Nature Genetics. 47: 106-14. PMID 25501392 DOI: 10.1038/Ng.3168 |
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| 2015 |
Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature. 518: 552-5. PMID 25487151 DOI: 10.1038/Nature13968 |
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| 2015 |
Okeyo-Owuor T, White BS, Chatrikhi R, Mohan DR, Kim S, Griffith M, Ding L, Ketkar-Kulkarni S, Hundal J, Laird KM, Kielkopf CL, Ley TJ, Walter MJ, Graubert TA. U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing. Leukemia. 29: 909-17. PMID 25311244 DOI: 10.1038/Leu.2014.303 |
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| 2015 |
Lu C, Zhang J, Nagahawatte P, Easton J, Lee S, Liu Z, Ding L, Wyczalkowski MA, Valentine M, Navid F, Mulder H, Tatevossian RG, Dalton J, Davenport J, Yin Z, et al. The genomic landscape of childhood and adolescent melanoma. The Journal of Investigative Dermatology. 135: 816-23. PMID 25268584 DOI: 10.1038/Jid.2014.425 |
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| 2015 |
Zhang J, McCastlain K, Qu C, Wu G, Edmonson M, Li Y, Wei L, Payne-Turner D, Yoshihara H, Churchman ML, Waanders E, Ntziachristos P, Aifantis I, Roberts KG, Ma J, ... ... Ding L, et al. Expression of an Oncogenic ERG isoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia Blood. 126: 693-693. DOI: 10.1182/Blood.V126.23.693.693 |
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| 2015 |
Sung H, Kanchi KL, Messina J, Lee J, Ding L, Wilson RK, Weber JS, Kim M. Abstract A05: Identification of RASA1 as a novel melanoma tumor suppressor gene Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-A05 |
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| 2015 |
Mertins P, Mani, Clauser K, Gillette M, Wang P, Qiao J, Fenyo D, Ruggles K, Davies S, Zhang B, Gatza M, Wang S, Yan P, Lin C, McLellan M, ... ... Ding L, et al. Abstract SY44-02: Proteogenomic and phosphoproteomic analysis of breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy44-02 |
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| 2015 |
Sengupta S, Ye K, Scott AD, Niu B, Bailey MH, McLellan MD, Wendl MC, Wyczalkowski MA, Ding L. Abstract 61: Sequence and structure-guided approach to identify functional mutations in G-protein coupled receptors Cancer Research. 75: 61-61. DOI: 10.1158/1538-7445.Am2015-61 |
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| 2015 |
Gunawardena HP, Wrobel JA, O'Brien J, Xie L, Erdmann-Gilmore P, Davies SR, Li S, Cao S, McLellan M, Ruggles KV, Fenyo D, Townsend RR, Ding L, Qaqish BF, Ellis MJ, et al. Abstract 1999: Proteogenomic characterization of breast cancer sub-types in patient derived xenografts Cancer Research. 75: 1999-1999. DOI: 10.1158/1538-7445.Am2015-1999 |
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Huang K, Wang J, Cao S, Xie M, Jayasinghe R, Ning J, McLellan M, Wendl M, Scott A, Johnson K, Davies S, Fenyö D, Townsend R, Chen F, Parvin J, ... ... Ding L, et al. Abstract 1939: Discovery and proteogenomic investigation of genetic variants in human cancers Cancer Research. 75: 1939-1939. DOI: 10.1158/1538-7445.Am2015-1939 |
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Jayasinghe RG, Huang K, Ning J, Wyczalkowski M, Lu C, Xie M, Wendl M, McLellan M, Ye K, Ding L. Abstract 1929: Pan-Cancer analysis of the effects of splice-altering variants on mRNA splicing and stability Cancer Research. 75: 1929-1929. DOI: 10.1158/1538-7445.Am2015-1929 |
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Mundt FO, Ma C, Mertins P, Guo Z, Meyer M, Qiao J, Mani, Clauser K, Li S, Huang K, Held J, Davies S, Ruggles K, Ding L, Gillette M, et al. Abstract C200: Effects of PI3K/Akt pathway inhibition on global proteome levels and phosphorylation signaling in patient-derived xenograft models of triple negative breast cancer Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C200 |
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| 2014 |
Ding L, Kim M, Kanchi KL, Dees ND, Lu C, Griffith M, Fenstermacher D, Sung H, Miller CA, Goetz B, Wendl MC, Griffith O, Cornelius LA, Linette GP, McMichael JF, et al. Clonal architectures and driver mutations in metastatic melanomas. Plos One. 9: e111153. PMID 25393105 DOI: 10.1371/Journal.Pone.0111153 |
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Xie M, Lu C, Wang J, McLellan MD, Johnson KJ, Wendl MC, McMichael JF, Schmidt HK, Yellapantula V, Miller CA, Ozenberger BA, Welch JS, Link DC, Walter MJ, Mardis ER, ... ... Ding L, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nature Medicine. 20: 1472-8. PMID 25326804 DOI: 10.1038/Nm.3733 |
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| 2014 |
Tirode F, Surdez D, Ma X, Parker M, Le Deley MC, Bahrami A, Zhang Z, Lapouble E, Grossetête-Lalami S, Rusch M, Reynaud S, Rio-Frio T, Hedlund E, Wu G, Chen X, ... ... Ding L, et al. Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations. Cancer Discovery. 4: 1342-53. PMID 25223734 DOI: 10.1158/2159-8290.Cd-14-0622 |
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| 2014 |
Liu Y, Patel L, Mills GB, Lu KH, Sood AK, Ding L, Kucherlapati R, Mardis ER, Levine DA, Shmulevich I, Broaddus RR, Zhang W. Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma. Journal of the National Cancer Institute. 106. PMID 25214561 DOI: 10.1093/Jnci/Dju245 |
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Roberts KG, Li Y, Payne-Turner D, Harvey RC, Yang YL, Pei D, McCastlain K, Ding L, Lu C, Song G, Ma J, Becksfort J, Rusch M, Chen SC, Easton J, et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. The New England Journal of Medicine. 371: 1005-15. PMID 25207766 DOI: 10.1056/Nejmoa1403088 |
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| 2014 |
Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MD, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, ... ... Ding L, et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell. 158: 929-44. PMID 25109877 DOI: 10.1016/J.Cell.2014.06.049 |
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Miller CA, White BS, Dees ND, Griffith M, Welch JS, Griffith OL, Vij R, Tomasson MH, Graubert TA, Walter MJ, Ellis MJ, Schierding W, DiPersio JF, Ley TJ, Mardis ER, ... ... Ding L, et al. SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution. Plos Computational Biology. 10: e1003665. PMID 25102416 DOI: 10.1371/Journal.Pcbi.1003665 |
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| 2014 |
Hughes AE, Magrini V, Demeter R, Miller CA, Fulton R, Fulton LL, Eades WC, Elliott K, Heath S, Westervelt P, Ding L, Conrad DF, White BS, Shao J, Link DC, et al. Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing. Plos Genetics. 10: e1004462. PMID 25010716 DOI: 10.1371/Journal.Pgen.1004462 |
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Ding L, Wendl MC, McMichael JF, Raphael BJ. Expanding the computational toolbox for mining cancer genomes. Nature Reviews. Genetics. 15: 556-70. PMID 25001846 DOI: 10.1038/Nrg3767 |
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| 2014 |
Huether R, Dong L, Chen X, Wu G, Parker M, Wei L, Ma J, Edmonson MN, Hedlund EK, Rusch MC, Shurtleff SA, Mulder HL, Boggs K, Vadordaria B, Cheng J, ... ... Ding L, et al. The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes. Nature Communications. 5: 3630. PMID 24710217 DOI: 10.1038/Ncomms4630 |
0.484 |
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| 2014 |
Wu G, Diaz AK, Paugh BS, Rankin SL, Ju B, Li Y, Zhu X, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Ma X, Lu C, Nagahawatte P, ... ... Ding L, et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nature Genetics. 46: 444-50. PMID 24705251 DOI: 10.1038/ng.2938 |
0.308 |
|
| 2014 |
Chen X, Bahrami A, Pappo A, Easton J, Dalton J, Hedlund E, Ellison D, Shurtleff S, Wu G, Wei L, Parker M, Rusch M, Nagahawatte P, Wu J, Mao S, ... ... Ding L, et al. Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. Cell Reports. 7: 104-12. PMID 24703847 DOI: 10.1016/J.Celrep.2014.03.003 |
0.459 |
|
| 2014 |
Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R, White E, Tang B, Orisme W, Gupta K, Rusch M, ... ... Ding L, et al. C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma. Nature. 506: 451-5. PMID 24553141 DOI: 10.1038/Nature13109 |
0.329 |
|
| 2014 |
Service SK, Teslovich TM, Fuchsberger C, Ramensky V, Yajnik P, Koboldt DC, Larson DE, Zhang Q, Lin L, Welch R, Ding L, McLellan MD, O'Laughlin M, Fronick C, Fulton LL, et al. Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci. Plos Genetics. 10: e1004147. PMID 24497850 DOI: 10.1371/Journal.Pgen.1004147 |
0.344 |
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| 2014 |
Kanchi KL, Johnson KJ, Lu C, McLellan MD, Leiserson MD, Wendl MC, Zhang Q, Koboldt DC, Xie M, Kandoth C, McMichael JF, Wyczalkowski MA, Larson DE, Schmidt HK, Miller CA, ... ... Ding L, et al. Integrated analysis of germline and somatic variants in ovarian cancer. Nature Communications. 5: 3156. PMID 24448499 DOI: 10.1038/Ncomms4156 |
0.69 |
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| 2014 |
Niu B, Ye K, Zhang Q, Lu C, Xie M, McLellan MD, Wendl MC, Ding L. MSIsensor: microsatellite instability detection using paired tumor-normal sequence data. Bioinformatics (Oxford, England). 30: 1015-6. PMID 24371154 DOI: 10.1093/Bioinformatics/Btt755 |
0.651 |
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| 2014 |
Chen K, Chen L, Fan X, Wallis J, Ding L, Weinstock G. TIGRA: a targeted iterative graph routing assembler for breakpoint assembly. Genome Research. 24: 310-7. PMID 24307552 DOI: 10.1101/Gr.162883.113 |
0.365 |
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| 2014 |
Zighelboim I, Mutch DG, Knapp A, Ding L, Xie M, Cohn DE, Goodfellow PJ. High Frequency Strand Slippage Mutations in CTCF in MSI-Positive Endometrial Cancers Human Mutation. 35: 63-65. PMID 24130125 DOI: 10.1002/Humu.22463 |
0.476 |
|
| 2014 |
Tripathi P, Wang Y, Coussens M, Manda KR, Casey AM, Lin C, Poyo E, Pfeifer JD, Basappa N, Bates CM, Ma L, Zhang H, Pan M, Ding L, Chen F. Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms. Oncogene. 33: 1840-9. PMID 23624921 DOI: 10.1038/Onc.2013.132 |
0.315 |
|
| 2014 |
Diaz AK, Wu G, Paugh BS, Li Y, Zhu X, Rankin S, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Lu C, Nagahawatte P, Hedlund E, Rusch M, ... ... Ding L, et al. Abstract PR03: The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Pr03 |
0.465 |
|
| 2014 |
Sung H, Ding L, Kanchi KL, Messina JL, Sondak VK, James MJ, Wilson RK, Weber JS, Kim M. Abstract 442:RASA1alteration promotes melanoma tumorigenesis Cancer Research. 74: 442-442. DOI: 10.1158/1538-7445.Am2014-442 |
0.431 |
|
| 2014 |
Wang J, Lu C, Xie M, Tripathi P, McLellan M, Chen F, Johnson KJ, Ding L. Abstract 3438: Integrated analysis of germline and somatic variants in renal clear cell carcinoma Cancer Research. 74: 3438-3438. DOI: 10.1158/1538-7445.Am2014-3438 |
0.516 |
|
| 2014 |
Gilbertson R, Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R, White E, Tang B, Orisme W, Gupta K, ... ... Ding L, et al. C11ORF95-RELA FUSIONS DRIVE ONCOGENIC NF-KB SIGNALING IN EPENDYMOMA Neuro-Oncology. 16: iii16-iii16. DOI: 10.1093/Neuonc/Nou206.57 |
0.395 |
|
| 2013 |
Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, ... ... Ding L, et al. Targeting oxidative stress in embryonal rhabdomyosarcoma. Cancer Cell. 24: 710-24. PMID 24332040 DOI: 10.1016/J.Ccr.2013.11.002 |
0.427 |
|
| 2013 |
Hamilton MP, Rajapakshe K, Hartig SM, Reva B, McLellan MD, Kandoth C, Ding L, Zack TI, Gunaratne PH, Wheeler DA, Coarfa C, McGuire SE. Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. Nature Communications. 4: 2730. PMID 24220575 DOI: 10.1038/Ncomms3730 |
0.31 |
|
| 2013 |
Kandoth C, McLellan MD, Vandin F, Ye K, Niu B, Lu C, Xie M, Zhang Q, McMichael JF, Wyczalkowski MA, Leiserson MD, Miller CA, Welch JS, Walter MJ, Wendl MC, ... ... Ding L, et al. Mutational landscape and significance across 12 major cancer types. Nature. 502: 333-9. PMID 24132290 DOI: 10.1038/Nature12634 |
0.705 |
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| 2013 |
Griffith M, Griffith OL, Coffman AC, Weible JV, McMichael JF, Spies NC, Koval J, Das I, Callaway MB, Eldred JM, Miller CA, Subramanian J, Govindan R, Kumar RD, Bose R, ... Ding L, et al. DGIdb: mining the druggable genome. Nature Methods. 10: 1209-10. PMID 24122041 DOI: 10.1038/Nmeth.2689 |
0.328 |
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| 2013 |
Ding L, Wendl MC. Differences that matter in cancer genomics. Nature Biotechnology. 31: 892-3. PMID 24104755 DOI: 10.1038/Nbt.2715 |
0.705 |
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| 2013 |
Tamborero D, Gonzalez-Perez A, Perez-Llamas C, Deu-Pons J, Kandoth C, Reimand J, Lawrence MS, Getz G, Bader GD, Ding L, Lopez-Bigas N. Comprehensive identification of mutational cancer driver genes across 12 tumor types. Scientific Reports. 3: 2650. PMID 24084849 DOI: 10.1038/Srep02650 |
0.481 |
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| 2013 |
Li S, Shen D, Shao J, Crowder R, Liu W, Prat A, He X, Liu S, Hoog J, Lu C, Ding L, Griffith OL, Miller C, Larson D, Fulton RS, et al. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Reports. 4: 1116-30. PMID 24055055 DOI: 10.1016/J.Celrep.2013.08.022 |
0.461 |
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| 2013 |
Chen K, Navin NE, Wang Y, Schmidt HK, Wallis JW, Niu B, Fan X, Zhao H, McLellan MD, Hoadley KA, Mardis ER, Ley TJ, Perou CM, Wilson RK, Ding L. BreakTrans: uncovering the genomic architecture of gene fusions. Genome Biology. 14: R87. PMID 23972288 DOI: 10.1186/Gb-2013-14-8-R87 |
0.444 |
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| 2013 |
Gonzalez-Perez A, Mustonen V, Reva B, Ritchie GR, Creixell P, Karchin R, Vazquez M, Fink JL, Kassahn KS, Pearson JV, Bader GD, Boutros PC, Muthuswamy L, Ouellette BF, Reimand J, ... ... Ding L, et al. Computational approaches to identify functional genetic variants in cancer genomes. Nature Methods. 10: 723-9. PMID 23900255 DOI: 10.1038/Nmeth.2562 |
0.503 |
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| 2013 |
Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I, Shen R, Benz CC, Yau C, Laird PW, Ding L, Zhang W, et al. Integrated genomic characterization of endometrial carcinoma. Nature. 497: 67-73. PMID 23636398 DOI: 10.1038/Nature12113 |
0.452 |
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| 2013 |
Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson G, Hoadley K, Triche TJ, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, et al. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia New England Journal of Medicine. 368: 2059-2074. PMID 23634996 DOI: 10.1056/Nejmoa1301689 |
0.634 |
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| 2013 |
Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop FA, Lu C, Kandoth C, Ding L, Lee R, et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nature Genetics. 45: 602-12. PMID 23583981 DOI: 10.1038/Ng.2611 |
0.391 |
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| 2013 |
Ewing AD, Ballinger TJ, Earl D, Harris CC, Ding L, Wilson RK, Haussler D. Retrotransposition of gene transcripts leads to structural variation in mammalian genomes. Genome Biology. 14: R22. PMID 23497673 DOI: 10.1186/Gb-2013-14-3-R22 |
0.387 |
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| 2013 |
Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, et al. Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia. 27: 1275-82. PMID 23443460 DOI: 10.1038/Leu.2013.58 |
0.443 |
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| 2013 |
Ding L, Raphael BJ, Chen F, Wendl MC. Advances for studying clonal evolution in cancer. Cancer Letters. 340: 212-9. PMID 23353056 DOI: 10.1016/J.Canlet.2012.12.028 |
0.68 |
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| 2013 |
Holmfeldt L, Wei L, Diaz-Flores E, Walsh M, Zhang J, Ding L, Payne-Turner D, Churchman M, Andersson A, Chen SC, McCastlain K, Becksfort J, Ma J, Wu G, Patel SN, et al. The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nature Genetics. 45: 242-52. PMID 23334668 DOI: 10.1038/Ng.2532 |
0.364 |
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| 2013 |
Gutmann DH, McLellan MD, Hussain I, Wallis JW, Fulton LL, Fulton RS, Magrini V, Demeter R, Wylie T, Kandoth C, Leonard JR, Guha A, Miller CA, Ding L, Mardis ER. Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma. Genome Research. 23: 431-9. PMID 23222849 DOI: 10.1101/Gr.142604.112 |
0.402 |
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| 2013 |
Bose R, Kavuri SM, Searleman AC, Shen W, Shen D, Koboldt DC, Monsey J, Goel N, Aronson AB, Li S, Ma CX, Ding L, Mardis ER, Ellis MJ. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discovery. 3: 224-37. PMID 23220880 DOI: 10.1158/2159-8290.Cd-12-0349 |
0.461 |
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| 2013 |
Neal Wong T, Ramsingh G, Young A, Shen D, Miller C, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch J, Walter MJ, Graubert T, DiPersio JF, et al. The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML Blood. 122: 5-5. DOI: 10.1182/Blood.V122.21.5.5 |
0.388 |
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| 2013 |
Ellis MJ, Li S, Shen D, Ding L, Crowder R, Shao J, Goncalves R, Tao Y, Luo J, Prat A, Liu W, Gonzalez-Angulo AM, Liu S, McMichael JF, Miller C, et al. Abstract LB-265: Patient-derived xenografts from advanced luminal-type breast cancer: insights into endocrine therapy resistance. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-265 |
0.391 |
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| 2013 |
Kandoth C, McLellan MD, Miller CA, Lu C, Dees N, Ye K, Niu B, Wendl MC, Wilson RK, Ding L. Abstract LB-239: Mutational and clonal analyses across TCGA cancer types using the MuSiC suite of tools. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-239 |
0.736 |
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| 2013 |
Dees ND, Miller CA, White BS, Schierding W, Vij R, Tomasson MH, Welch JS, Graubert TA, Walter MJ, Ley TJ, DiPersio JF, Mardis ER, Wilson RK, Ding L. Abstract LB-232: Tumor clonality detection using next generation sequencing data. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-232 |
0.431 |
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| 2013 |
Kim M, Ding L, Dees N, Kanchi KL, Sung H, Fenstermacher D, Griffith M, Linette G, Cornelius L, Sondak VK, Mulé JJ, Wilson RK, Weber JS. Abstract 3170: Identification of novel genetic alterations driving melanoma tumorigenesis. Cancer Research. 73: 3170-3170. DOI: 10.1158/1538-7445.Am2013-3170 |
0.539 |
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| 2013 |
Gonzalez-Perez A, Tamborero D, Lopez-Bigas N, Margolin A, Ding L, Gordenin D, Axton M. Thread 1: Mutational drivers Nature Genetics. 1-1. DOI: 10.1038/Ng.2786 |
0.367 |
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| 2013 |
Ding L, Wendl MC. Erratum: Differences that matter in cancer genomics Nature Biotechnology. 31: 1148-1148. DOI: 10.1038/Nbt1213-1148D |
0.609 |
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| 2012 |
Quayle SN, Lee JY, Cheung LW, Ding L, Wiedemeyer R, Dewan RW, Huang-Hobbs E, Zhuang L, Wilson RK, Ligon KL, Mills GB, Cantley LC, Chin L. Somatic mutations of PIK3R1 promote gliomagenesis. Plos One. 7: e49466. PMID 23166678 DOI: 10.1371/Journal.Pone.0049466 |
0.449 |
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| 2012 |
Gruber TA, Larson Gedman A, Zhang J, Koss CS, Marada S, Ta HQ, Chen SC, Su X, Ogden SK, Dang J, Wu G, Gupta V, Andersson AK, Pounds S, Shi L, ... ... Ding L, et al. An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell. 22: 683-97. PMID 23153540 DOI: 10.1016/J.Ccr.2012.10.007 |
0.331 |
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| 2012 |
Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell. 150: 1121-34. PMID 22980976 DOI: 10.1016/J.Cell.2012.08.024 |
0.474 |
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| 2012 |
Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, ... ... Ding L, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 150: 264-78. PMID 22817890 DOI: 10.1016/J.Cell.2012.06.023 |
0.463 |
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| 2012 |
Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, Reid JG, Santibanez J, Shinbrot E, Trevino LR, Wu YQ, ... ... Ding L, et al. Comprehensive molecular characterization of human colon and rectal cancer Nature. 487: 330-337. PMID 22810696 DOI: 10.1038/Nature11252 |
0.511 |
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| 2012 |
Dees ND, Zhang Q, Kandoth C, Wendl MC, Schierding W, Koboldt DC, Mooney TB, Callaway MB, Dooling D, Mardis ER, Wilson RK, Ding L. MuSiC: Identifying mutational significance in cancer genomes Genome Research. 22: 1589-1598. PMID 22759861 DOI: 10.1101/Gr.134635.111 |
0.72 |
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| 2012 |
Lee E, Iskow R, Yang L, Gokcumen O, Haseley P, Luquette LJ, Lohr JG, Harris CC, Ding L, Wilson RK, Wheeler DA, Gibbs RA, Kucherlapati R, Lee C, Kharchenko PV, et al. Landscape of somatic retrotransposition in human cancers. Science (New York, N.Y.). 337: 967-71. PMID 22745252 DOI: 10.1126/Science.1222077 |
0.5 |
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| 2012 |
Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, et al. Novel mutations target distinct subgroups of medulloblastoma. Nature. 488: 43-8. PMID 22722829 DOI: 10.1038/Nature11213 |
0.452 |
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| 2012 |
Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 486: 353-60. PMID 22722193 DOI: 10.1038/Nature11143 |
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| 2012 |
Downing JR, Wilson RK, Zhang J, Mardis ER, Pui CH, Ding L, Ley TJ, Evans WE. The Pediatric Cancer Genome Project. Nature Genetics. 44: 619-22. PMID 22641210 DOI: 10.1038/Ng.2287 |
0.482 |
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| 2012 |
Chen K, Wallis JW, Kandoth C, Kalicki-Veizer JM, Mungall KL, Mungall AJ, Jones SJ, Marra MA, Ley TJ, Mardis ER, Wilson RK, Weinstein JN, Ding L. BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data. Bioinformatics (Oxford, England). 28: 1923-4. PMID 22563071 DOI: 10.1093/Bioinformatics/Bts272 |
0.34 |
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| 2012 |
Young MA, Larson DE, Sun CW, George DR, Ding L, Miller CA, Lin L, Pawlik KM, Chen K, Fan X, Schmidt H, Kalicki-Veizer J, Cook LL, Swift GW, Demeter RT, et al. Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells. Cell Stem Cell. 10: 570-82. PMID 22542160 DOI: 10.1016/J.Stem.2012.03.002 |
0.632 |
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| 2012 |
Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, et al. Clonal architecture of secondary acute myeloid leukemia. The New England Journal of Medicine. 366: 1090-8. PMID 22417201 DOI: 10.1056/Nejmoa1106968 |
0.397 |
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| 2012 |
Cheung NK, Zhang J, Lu C, Parker M, Bahrami A, Tickoo SK, Heguy A, Pappo AS, Federico S, Dalton J, Cheung IY, Ding L, Fulton R, Wang J, Chen X, et al. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. Jama. 307: 1062-71. PMID 22416102 DOI: 10.1001/Jama.2012.228 |
0.369 |
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| 2012 |
Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L, Miller CA, Mardis ER, Ding L, Wilson RK. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Research. 22: 568-76. PMID 22300766 DOI: 10.1101/Gr.129684.111 |
0.511 |
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| 2012 |
Chen F, Ding L. Co-survival of the fittest few: mosaic amplification of receptor tyrosine kinases in glioblastoma. Genome Biology. 13: 141. PMID 22289423 DOI: 10.1186/Gb-2012-13-1-141 |
0.336 |
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| 2012 |
Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, Zhang J, Gajjar A, Dyer MA, Mullighan CG, Gilbertson RJ, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nature Genetics. 44: 251-3. PMID 22286216 DOI: 10.1038/Ng.1102 |
0.38 |
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| 2012 |
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 481: 157-63. PMID 22237106 DOI: 10.1038/Nature10725 |
0.417 |
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| 2012 |
Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 481: 506-10. PMID 22237025 DOI: 10.1038/Nature10738 |
0.663 |
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| 2012 |
Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, et al. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature. 481: 329-34. PMID 22237022 DOI: 10.1038/Nature10733 |
0.504 |
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| 2012 |
Koboldt DC, Larson DE, Chen K, Ding L, Wilson RK. Massively parallel sequencing approaches for characterization of structural variation. Methods in Molecular Biology (Clifton, N.J.). 838: 369-84. PMID 22228022 DOI: 10.1007/978-1-61779-507-7_18 |
0.373 |
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| 2012 |
Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nature Genetics. 44: 53-7. PMID 22158538 DOI: 10.1038/Ng.1031 |
0.422 |
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| 2012 |
Larson DE, Harris CC, Chen K, Koboldt DC, Abbott TE, Dooling DJ, Ley TJ, Mardis ER, Wilson RK, Ding L. SomaticSniper: identification of somatic point mutations in whole genome sequencing data. Bioinformatics (Oxford, England). 28: 311-7. PMID 22155872 DOI: 10.1093/Bioinformatics/Btr665 |
0.457 |
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| 2012 |
Robinson GW, Parker M, Kranenburg T, Lu C, Chen X, Ding L, Phoenix T, Huether R, Thiruvenkatam R, Wang J, Easton J, Onar-Thomas A, Gajjar AJ, Ellison DW, Mardis E, et al. Use of whole genome sequencing to identify novel mutations in distinct subgroups of medulloblastoma. Journal of Clinical Oncology. 30: 9518-9518. DOI: 10.1200/Jco.2012.30.15_Suppl.9518 |
0.475 |
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| 2012 |
Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Goiffon RJ, Wallis JW, Goldstein TC, Chen K, Allred DC, Leitch AM, Olson JA, Ota DM, Watson M, Piwnica-Worms D, et al. Whole genome sequencing to characterize luminal-type breast cancer. Journal of Clinical Oncology. 30: 503-503. DOI: 10.1200/Jco.2012.30.15_Suppl.503 |
0.489 |
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| 2012 |
Lee E, Iskow R, Yang L, Gokcumen O, Haseley P, Luquette LJ, Lohr JG, Harris CC, Ding L, Wilson RK, Wheeler DA, Gibbs RA, Kucherlapati R, Lee C, Kharchenko PV, et al. Analysis of somatic retrotransposition in human cancers Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-O23 |
0.393 |
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| 2012 |
Mardis ER, Ding L, Westervelt P, Welch JS, Klco JM, DiPersio JF, Wilson RK, Ley TJ. Next-Generation Sequencing: A Discovery Tool for Blood Disorders Blood. 120: SCI-10-SCI-10. DOI: 10.1182/Blood.V120.21.Sci-10.Sci-10 |
0.498 |
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| 2012 |
Ramsingh G, Shen D, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch JS, Walter MJ, Graubert T, DiPersio JF, Ley TJ, Wilson RK, Link DC. Whole Genome Sequencing of Therapy-Related Acute Myeloid Leukemia Blood. 120: 784-784. DOI: 10.1182/Blood.V120.21.784.784 |
0.412 |
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| 2012 |
Klco JM, Spencer DH, Miller C, Lamprecht T, Fulton RS, Welch JS, Ding L, Wilson RK, Ley TJ. Deep Digital Sequencing Identifies an AML Subclone with Enhanced in Vitro and in Vivo Growth Properties Associated with Disease Relapse Blood. 120: 407-407. DOI: 10.1182/Blood.V120.21.407.407 |
0.382 |
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| 2012 |
Tomasson MH, Shen D, Hucthagowder V, Schierding W, Mullins CD, Fiala M, Hall IM, Wallis J, Fulton RS, Fulton LA, Kulkarni S, Mardis ER, Wilson RK, Ley TJ, DiPersio JF, ... ... Ding L, et al. Whole Genome Sequencing Reveals Novel Recurring Somatic Mutations Affecting HUWE1 and DIAPH2 Genes in Multiple Myeloma Blood. 120: 320-320. DOI: 10.1182/Blood.V120.21.320.320 |
0.47 |
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| 2012 |
Mardis ER, Humphrey P, McGrath S, Demeter R, Magrini V, Dees N, Kanthi K, Maher C, Ding L, Kibel A. Abstract IA2: Genomic comparisons of coincident prostate cancer foci Cancer Research. 72: IA2-IA2. DOI: 10.1158/1538-7445.Prca2012-Ia2 |
0.403 |
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| 2012 |
Parker MD, Wu G, Chen X, Rusch M, Bahrami A, Ding L, Mardis E, Mullighan C, Gilbertson R, Dyer MA, Wilson RK, Downing J, Zhang J. Abstract 4873: Comprehensive analysis of 160 whole-genome sequences reveals striking telomere alteration patterns in 9 pediatric cancers Cancer Research. 72: 4873-4873. DOI: 10.1158/1538-7445.Am2012-4873 |
0.478 |
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| 2012 |
Andersson A, Ma J, Wang J, Chen X, Rusch M, Wu G, Easton J, Parker M, Raimondi S, Holmfeldt L, Becksfort J, Gupta P, Gedman A, Nakitandwe J, Payne-Turner D, ... ... Ding L, et al. Abstract 4869: Whole genome sequence analysis of MLL rearranged infant acute lymphoblastic leukemias reveals remarkably few somatic mutations: A Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project Cancer Research. 72: 4869-4869. DOI: 10.1158/1538-7445.Am2012-4869 |
0.446 |
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| 2012 |
Gruber TA, Gedman AL, Ta H, Zhang J, Koss C, Marada S, Chen S, Su X, Ogden S, Gupta V, Andersson A, Pounds S, Shi L, Easton J, Wang J, ... ... Ding L, et al. Abstract 4867: Identification of an inv(16)-encodedCBFA2T3-GLIS2fusion protein in 34% of non-infant acute megkaryoblastic leukemias: A report from the Pediatric Cancer Genome Project Cancer Research. 72: 4867-4867. DOI: 10.1158/1538-7445.Am2012-4867 |
0.346 |
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| 2012 |
Bose R, Kavuri S, Searleman A, Shen W, Shen D, Koboldt D, Monsey J, Li S, Ding L, Mardis E, Ellis M. Abstract S5-6: Activating HER2 mutations in HER2 gene amplification negative breast cancers. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-S5-6 |
0.488 |
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| 2012 |
Downing JR, Wilson RK, Zhang J, Mardis ER, Pui C, Ding L, Ley TJ, Evans WE. Erratum: The Pediatric Cancer Genome Project Nature Genetics. 44: 1072-1072. DOI: 10.1038/Ng0912-1072C |
0.34 |
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| 2012 |
Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YSN, Carlsen R, et al. Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70. DOI: 10.1038/Nature11412 |
0.451 |
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| 2011 |
Bell D, Berchuck A, Birrer M, Chien J, Cramer DW, Dao F, Dhir R, Disaia P, Gabra H, Glenn P, Godwin AK, Gross J, Hartmann L, Huang M, Huntsman DG, ... ... Ding L, et al. Integrated genomic analyses of ovarian carcinoma Nature. 474: 609-615. PMID 21720365 DOI: 10.1038/Nature10166 |
0.688 |
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| 2011 |
Wang J, Mullighan CG, Easton J, Roberts S, Heatley SL, Ma J, Rusch MC, Chen K, Harris CC, Ding L, Holmfeldt L, Payne-Turner D, Fan X, Wei L, Zhao D, et al. CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nature Methods. 8: 652-4. PMID 21666668 DOI: 10.1038/Nmeth.1628 |
0.371 |
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| 2011 |
Bowne SJ, Humphries MM, Sullivan LS, Kenna PF, Tam LC, Kiang AS, Campbell M, Weinstock GM, Koboldt DC, Ding L, Fulton RS, Sodergren EJ, Allman D, Millington-Ward S, Palfi A, et al. A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement. European Journal of Human Genetics : Ejhg. 19: 1074-81. PMID 21654732 DOI: 10.1038/Ejhg.2011.86 |
0.422 |
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| 2011 |
Welch JS, Westervelt P, Ding L, Larson DE, Klco JM, Kulkarni S, Wallis J, Chen K, Payton JE, Fulton RS, Veizer J, Schmidt H, Vickery TL, Heath S, Watson MA, et al. Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. Jama. 305: 1577-84. PMID 21505136 DOI: 10.1001/Jama.2011.497 |
0.387 |
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| 2011 |
Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, ... ... Ding L, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/Jama.2011.473 |
0.51 |
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| 2011 |
Wendl MC, Wallis JW, Lin L, Kandoth C, Mardis ER, Wilson RK, Ding L. PathScan: a tool for discerning mutational significance in groups of putative cancer genes. Bioinformatics (Oxford, England). 27: 1595-602. PMID 21498403 DOI: 10.1093/Bioinformatics/Btr193 |
0.7 |
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| 2011 |
Wartman LD, Larson DE, Xiang Z, Ding L, Chen K, Lin L, Cahan P, Klco JM, Welch JS, Li C, Payton JE, Uy GL, Varghese N, Ries RE, Hoock M, et al. Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. The Journal of Clinical Investigation. 121: 1445-55. PMID 21436584 DOI: 10.1172/Jci45284 |
0.44 |
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| 2011 |
Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Kandoth C, Baty J, Westervelt P, Dipersio JF, Mardis ER, et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes Leukemia. 25: 1153-1158. PMID 21415852 DOI: 10.1182/Blood.V116.21.608.608 |
0.406 |
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| 2011 |
Mills RE, Walter K, Stewart C, Handsaker RE, Chen K, Alkan C, Abyzov A, Yoon SC, Ye K, Cheetham RK, Chinwalla A, Conrad DF, Fu Y, Grubert F, Hajirasouliha I, ... ... Ding L, et al. Mapping copy number variation by population-scale genome sequencing. Nature. 470: 59-65. PMID 21293372 DOI: 10.1038/Nature09708 |
0.368 |
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| 2011 |
Bowne SJ, Sullivan LS, Koboldt DC, Ding L, Fulton R, Abbott RM, Sodergren EJ, Birch DG, Wheaton DH, Heckenlively JR, Liu Q, Pierce EA, Weinstock GM, Daiger SP. Identification of disease-causing mutations in autosomal dominant retinitis pigmentosa (adRP) using next-generation DNA sequencing. Investigative Ophthalmology & Visual Science. 52: 494-503. PMID 20861475 DOI: 10.1167/Iovs.10-6180 |
0.376 |
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| 2011 |
Gruber TA, Gedman AL, Ta HQ, Zhang J, Koss C, Chen S, Su X, Gupta V, Ogden S, Andersson AK, Easton J, Wang J, Rusch M, Ding L, Cazzaniga G, et al. Transcriptome Sequence Analysis of Pediatric Acute Megakaryoblastic Leukemia Identifies An Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases: A Report From the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project Blood. 118: 757-757. DOI: 10.1182/Blood.V118.21.757.757 |
0.407 |
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| 2011 |
Andersson AK, Ma J, Wang J, Chen X, Rusch M, Wu G, Easton J, Parker M, Raimondi SC, Holmfeldt L, Gedman AL, Song G, Becksfort J, Gupta P, Ulyanov A, ... ... Ding L, et al. Whole Genome Sequence Analysis of 22 MLL Rearranged Infant Acute Lymphoblastic Leukemias Reveals Remarkably Few Somatic Mutations: A Report From the St Jude Children‘s Research Hospital - Washington University Pediatric Cancer Genome Project Blood. 118: 69-69. DOI: 10.1182/Blood.V118.21.69.69 |
0.451 |
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| 2011 |
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen S, Collins-Underwood R, Ma J, Roberts KG, et al. Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project Blood. 118: 68-68. DOI: 10.1182/Blood.V118.21.68.68 |
0.468 |
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| 2011 |
Welch JS, Larson D, Ding L, McLellan MD, Lamprecht T, Kandoth C, Payton JE, Baty J, Harris CC, Lichti CF, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, et al. Complete Sequencing and Comparison of 12 Normal Karyotype M1 AML Genomes with 12 t(15;17) Positive M3-APL Genomes Blood. 118: 404-404. DOI: 10.1182/Blood.V118.21.404.404 |
0.461 |
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| 2011 |
Ellis MJ, Ding L, Shen D, Wallis J, Suman V, Luo J, Tao Y, Hoog J, Davies S, Lin L, Perou C, Tine BV, Bose R, Chang LW, Chen K, et al. Abstract LB-87: Analysis of luminal-type breast cancer by massively parallel sequencing Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-87 |
0.504 |
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| 2011 |
Bowne SJ, Humphries MM, Sullivan LS, Kenna PF, Tam LC, Kiang AS, Campbell M, Weinstock GM, Koboldt DC, Ding L, Fulton RS, Sodergren EJ, Allman D, Millington-Ward S, Palfi A, et al. Erratum: A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement European Journal of Human Genetics. 19: 1109-1109. DOI: 10.1038/Ejhg.2011.132 |
0.369 |
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| 2010 |
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, et al. DNMT3A mutations in acute myeloid leukemia. The New England Journal of Medicine. 363: 2424-33. PMID 21067377 DOI: 10.1056/Nejmoa1005143 |
0.397 |
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| 2010 |
Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, Chang LW, Nagarajan R, Fehniger TA, Goodfellow P, Magrini V, Wilson RK, Ding L, Ley TJ, Mardis ER, et al. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood. 116: 5316-26. PMID 20876853 DOI: 10.1182/Blood-2010-05-285395 |
0.351 |
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| 2010 |
Ding L, Wendl MC, Koboldt DC, Mardis ER. Analysis of next-generation genomic data in cancer: Accomplishments and challenges Human Molecular Genetics. 19: R188-R196. PMID 20843826 DOI: 10.1093/Hmg/Ddq391 |
0.702 |
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| 2010 |
Koboldt DC, Ding L, Mardis ER, Wilson RK. Challenges of sequencing human genomes Briefings in Bioinformatics. 11: 484-498. PMID 20519329 DOI: 10.1093/Bib/Bbq016 |
0.332 |
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| 2010 |
Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, ... Ding L, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 17: 510-22. PMID 20399149 DOI: 10.1016/J.Ccr.2010.03.017 |
0.379 |
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| 2010 |
Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, Harris CC, McLellan MD, Fulton RS, Fulton LL, Abbott RM, Hoog J, Dooling DJ, Koboldt DC, Schmidt H, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature. 464: 999-1005. PMID 20393555 DOI: 10.1038/Nature08989 |
0.679 |
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| 2010 |
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 17: 98-110. PMID 20129251 DOI: 10.1016/J.Ccr.2009.12.020 |
0.448 |
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| 2010 |
Zhang Q, Ding L, Larson DE, Koboldt DC, McLellan MD, Chen K, Shi X, Kraja A, Mardis ER, Wilson RK, Borecki IB, Province MA. CMDS: a population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data. Bioinformatics (Oxford, England). 26: 464-9. PMID 20031968 DOI: 10.1093/Bioinformatics/Btp708 |
0.362 |
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| 2010 |
Mardis E, Ding L, Li S, Larson DE, Chen K, Wallis J, Hoog J, Deshryver K, Wilson R, Ellis MJ. Massive parallel sequencing of an African-American basal-like breast cancer: Comparison of primary tumor, metastasis, and xenograft. Journal of Clinical Oncology. 28: 10500-10500. DOI: 10.1200/Jco.2010.28.15_Suppl.10500 |
0.469 |
|
| 2010 |
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch JS, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, et al. Mutations In the DNA Methyltransferase Gene DNMT3A Are Highly Recurrent In Patients with Intermediate Risk Acute Myeloid Leukemia, and Predict Poor Outcomes Blood. 116: 99-99. DOI: 10.1182/Blood.V116.21.99.99 |
0.455 |
|
| 2010 |
Schuettpelz L, Link DC, Shen D, Walter MJ, Koboldt DC, Dooling DJ, Fulton RS, Schmidt H, Maupin R, O'Laughlin M, Chen K, McLellan MD, Kulkarni S, Ivanovich J, Lebeau M, ... ... Ding L, et al. DNA Sequence of the Cancer Genome of a Patient with Therapy-Related Acute Myeloid Leukemia Blood. 116: 580-580. DOI: 10.1182/Blood.V116.21.580.580 |
0.459 |
|
| 2010 |
Walter MJ, Shen D, Ding L, Shao J, Witowski S, Chen K, Koboldt DC, Dooling DJ, Maupin R, Fulton RS, Schmidt H, O'Laughlin M, McLellan MD, Frater J, Westervelt P, et al. Detection of Novel Mutations In MDS/AML by Whole Genome Sequencing Blood. 116: 299-299. DOI: 10.1182/Blood.V116.21.299.299 |
0.465 |
|
| 2010 |
Welch JS, Ding L, Chen K, Larson DE, Kulkarni S, Payton JE, Wallis J, Veizer J, McLellan MD, Vickery TL, Reed JP, Koboldt DC, Klco J, DiPersio JF, Mardis ER, et al. Resolution of a Clinical Dilemma with Whole Genome Sequencing, and Discovery of a New Mechanism for Generating PML-Rara: Insertional Fusion Blood. 116: 2755-2755. DOI: 10.1182/Blood.V116.21.2755.2755 |
0.374 |
|
| 2010 |
Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, Chang L, Nagarajan R, Fehniger TA, Goodfellow P, Magrini V, Wilson RK, Ding L, Ley TJ, Mardis ER, et al. Abstract B12: Complete characterization of the “microRNAome” of a human acute myeloid leukemia Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-B12 |
0.332 |
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| 2010 |
Mardis E, Ding L, Shen D, Wallis J, Chen K, Watson M, Hoog J, Ellis M, Rk W. Abstract ES7-1: Next Generation Sequencing for the Clinician: A Breast Cancer Study Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Es7-1 |
0.433 |
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| 2010 |
Zhang J, Finney R, Edmonson M, Schaefer C, Rowe W, Yan C, Clifford R, Greenblum S, Wu G, Zhang H, Liu H, Nguyen C, Hu Y, Madhavan S, Ding L, et al. The Cancer Genome Workbench: Identifying and Visualizing Complex Genetic Alterations in Tumors Nci Nature Pathway Interaction Database. DOI: 10.1038/Pid.2010.1 |
0.403 |
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| 2009 |
Chen K, Wallis JW, McLellan MD, Larson DE, Kalicki JM, Pohl CS, McGrath SD, Wendl MC, Zhang Q, Locke DP, Shi X, Fulton RS, Ley TJ, Wilson RK, Ding L, et al. BreakDancer: an algorithm for high-resolution mapping of genomic structural variation. Nature Methods. 6: 677-81. PMID 19668202 DOI: 10.1038/Nmeth.1363 |
0.631 |
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| 2009 |
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, Fulton LA, Locke DP, Magrini VJ, Abbott RM, Vickery TL, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. The New England Journal of Medicine. 361: 1058-66. PMID 19657110 DOI: 10.1056/Nejmoa0903840 |
0.477 |
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| 2009 |
Koboldt DC, Chen K, Wylie T, Larson DE, McLellan MD, Mardis ER, Weinstock GM, Wilson RK, Ding L. VarScan: variant detection in massively parallel sequencing of individual and pooled samples. Bioinformatics (Oxford, England). 25: 2283-5. PMID 19542151 DOI: 10.1093/Bioinformatics/Btp373 |
0.34 |
|
| 2009 |
Wartman LD, Ding L, Larson DE, McLellan MD, Schmidt H, Xiang Z, Tomasson M, Mardis E, Wilson RK, Ley TJ. DNA Sequencing of a Murine Acute Promyelocytic Leukemia (APL) Genome Using Next Generation Technology. Blood. 114: 3965-3965. DOI: 10.1182/Blood.V114.22.3965.3965 |
0.481 |
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| 2008 |
Sharp TV, Al-Attar A, Foxler DE, Ding L, de A Vallim TQ, Zhang Y, Nijmeh HS, Webb TM, Nicholson AG, Zhang Q, Kraja A, Spendlove I, Osborne J, Mardis E, Longmore GD. The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development. Proceedings of the National Academy of Sciences of the United States of America. 105: 19932-7. PMID 19060205 DOI: 10.1073/Pnas.0805003105 |
0.389 |
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| 2008 |
Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, Cook L, Abbott R, Larson DE, Koboldt DC, Pohl C, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature. 456: 66-72. PMID 18987736 DOI: 10.1038/Nature07485 |
0.48 |
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| 2008 |
Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 455: 1069-75. PMID 18948947 DOI: 10.1038/Nature07423 |
0.681 |
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| 2008 |
McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis GM, Olson JJ, Mikkelsen T, Lehman N, Aldape K, Yung WKA, Bogler O, Weinstein JN, VandenBerg S, Berger M, ... ... Ding L, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature. 455: 1061-1068. PMID 18772890 DOI: 10.1038/Nature07385 |
0.702 |
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| 2008 |
Marks JL, Gong Y, Chitale D, Golas B, McLellan MD, Kasai Y, Ding L, Mardis ER, Wilson RK, Solit D, Levine R, Michel K, Thomas RK, Rusch VW, Ladanyi M, et al. Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma. Cancer Research. 68: 5524-8. PMID 18632602 DOI: 10.1158/0008-5472.Can-08-0099 |
0.394 |
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| 2007 |
Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 450: 893-8. PMID 17982442 DOI: 10.1038/Nature06358 |
0.417 |
|
| 2007 |
Chen K, McLellan MD, Ding L, Wendl MC, Kasai Y, Wilson RK, Mardis ER. PolyScan: an automatic indel and SNP detection approach to the analysis of human resequencing data. Genome Research. 17: 659-66. PMID 17416743 DOI: 10.1101/Gr.6151507 |
0.659 |
|
| 2007 |
Ley TJ, DiPersio J, Ding L, Ries R, Magrini V, Payton J, McGrath S, Walter M, Wylie T, Dunford-Shore B, Chen K, McLellan M, Wendl M, Dooling D, Cook L, et al. Sequencing an Acute Myeloid Leukemia (AML) Genome with “Next Generation” Technologies. Blood. 110: 205-205. DOI: 10.1182/Blood.V110.11.205.205 |
0.682 |
|
| 2006 |
Ma XJ, Hilsenbeck SG, Wang W, Ding L, Sgroi DC, Bender RA, Osborne CK, Allred DC, Erlander MG. The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4611-9. PMID 17008703 DOI: 10.1200/Jco.2006.06.6944 |
0.342 |
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| 2006 |
McDill BW, Li SZ, Kovach PA, Ding L, Chen F. Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation. Proceedings of the National Academy of Sciences of the United States of America. 103: 6952-7. PMID 16641094 DOI: 10.1073/Pnas.0602087103 |
0.37 |
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| 2005 |
Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, ... ... Ding L, et al. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature. 434: 724-31. PMID 15815621 DOI: 10.1038/Nature03466 |
0.589 |
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| 2004 |
Ding L, Sabo A, Berkowicz N, Meyer RR, Shotland Y, Johnson MR, Pepin KH, Wilson RK, Spieth J. EAnnot: a genome annotation tool using experimental evidence. Genome Research. 14: 2503-9. PMID 15574829 DOI: 10.1101/Gr.3152604 |
0.372 |
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| 2003 |
Sincock PM, Ganley IG, Krise JP, Diederichs S, Sivars U, O'Connor B, Ding L, Pfeffer SR. Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport. Traffic (Copenhagen, Denmark). 4: 18-25. PMID 12535272 DOI: 10.1034/J.1600-0854.2003.40104.X |
0.698 |
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| 1997 |
Ding L, Bunting M, Topham MK, McIntyre TM, Zimmerman GA, Prescott SM. Alternative splicing of the human diacylglycerol kinase zeta gene in muscle. Proceedings of the National Academy of Sciences of the United States of America. 94: 5519-24. PMID 9159104 DOI: 10.1073/Pnas.94.11.5519 |
0.353 |
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