William MacNee - Publications

Affiliations: 
Pulmonology University of Edinburgh, Edinburgh, Scotland, United Kingdom 
Area:
Pulmonology
Website:
https://www.ed.ac.uk/inflammation-research/people/associate-members/professor-william-macnee

329 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Fermont JM, Mohan D, Fisk M, Bolton CE, Macnee W, Cockcroft JR, McEniery C, Fuld J, Cheriyan J, Tal-Singer R, Müllerova H, Wood AM, Wilkinson IB, Polkey MI. Short physical performance battery as a practical tool to assess mortality risk in chronic obstructive pulmonary disease. Age and Ageing. PMID 32894757 DOI: 10.1093/Ageing/Afaa138  0.363
2020 Fermont JM, Bolton CE, Fisk M, Mohan D, Macnee W, Cockcroft JR, McEniery C, Fuld J, Cheriyan J, Tal-Singer R, Wilkinson IB, Wood AM, Polkey MI, Müllerova H. Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study. Plos One. 15: e0228940. PMID 32040531 DOI: 10.1371/Journal.Pone.0228940  0.301
2020 Mohan D, Benson VS, Allinder M, Galwey N, Bolton CE, Cockcroft JR, MacNee W, Wilkinson IB, Tal-Singer R, Polkey MI. Short Physical Performance Battery: What Does Each Sub-Test Measure in Patients with Chronic Obstructive Pulmonary Disease? Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 7: 13-25. PMID 31999899 DOI: 10.15326/Jcopdf.7.1.2019.0144  0.32
2019 MacNee W. Beta-Blockers in COPD - A Controversy Resolved? The New England Journal of Medicine. PMID 31633892 DOI: 10.1056/Nejme1912664  0.382
2019 Stolk J, Tov N, Chapman KR, Fernandez P, MacNee W, Hopkinson NS, Piitulainen E, Seersholm N, Vogelmeier CF, Bals R, McElvaney G, Stockley RA. Efficacy and safety of inhaled alpha-1-antitrypsin in patients with severe alpha-1-antitrypsin deficiency and frequent exacerbations of Chronic Obstructive Pulmonary Disease. The European Respiratory Journal. PMID 31467115 DOI: 10.1183/13993003.00673-2019  0.347
2018 MacNee W, Fahy JV, Nicod LP, Kolls J. Purpose of the Conference: The 2018 Transatlantic Conference on Lung Diseases. Annals of the American Thoracic Society. 15: S139. PMID 30431342 DOI: 10.1513/Annalsats.201810-675Aw  0.358
2018 Mohan D, Forman JR, Allinder M, McEniery CM, Bolton CE, Cockcroft JR, MacNee W, Fuld J, Marchong M, Gale NS, Fisk M, Nagarajan S, Cheriyan J, Lomas DA, Calverley PMA, et al. Fibrinogen does not relate to cardiovascular or muscle manifestations in COPD: cross-sectional data from the ERICA study. Thorax. PMID 29618495 DOI: 10.1136/Thoraxjnl-2018-211556  0.375
2018 Wilkinson T, Schembri S, Brightling C, Bakerly ND, Macnee W, Rombo L, Hedner J, Allen M, Walker P, Ryck ID, Tasciotti A, Casula D, Testa M, Arora AK. Late Breaking Abstract - Safety and immunogenicity of non-typeable H. influenzae (NTHi) adjuvanted vaccine in older adults with chronic obstructive pulmonary disease (COPD) European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa4089  0.318
2017 MacNee W, Fahy JV, Nicod LP, Kolls J. Purpose of the Conference: The 2017 Transatlantic Conference on Lung Diseases. Annals of the American Thoracic Society. 14: S313. PMID 29161085 DOI: 10.1513/Annalsats.201711-858Aw  0.358
2017 Mantoani LC, Dell'Era S, MacNee W, Rabinovich RA. Physical activity in patients with COPD: the impact of comorbidities. Expert Review of Respiratory Medicine. 11: 685-698. PMID 28699821 DOI: 10.1080/17476348.2017.1354699  0.358
2017 Lakhdar R, Drost EM, MacNee W, Bastos R, Rabinovich RA. 2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls. Respiratory Research. 18: 81. PMID 28468631 DOI: 10.1186/S12931-017-0525-X  0.338
2017 Rubio N, Parker RA, Drost EM, Pinnock H, Weir CJ, Hanley J, Mantoani LC, MacNee W, McKinstry B, Rabinovich RA. Home monitoring of breathing rate in people with chronic obstructive pulmonary disease: observational study of feasibility, acceptability, and change after exacerbation. International Journal of Chronic Obstructive Pulmonary Disease. 12: 1221-1231. PMID 28458534 DOI: 10.2147/Copd.S120706  0.38
2017 Martin M, Almeras N, Després JP, Coxson HO, Washko GR, Vivodtzev I, Wouters EF, Rutten E, Williams MC, Murchison JT, MacNee W, Sin DD, Maltais F. Ectopic fat accumulation in patients with COPD: an ECLIPSE substudy. International Journal of Chronic Obstructive Pulmonary Disease. 12: 451-460. PMID 28203068 DOI: 10.2147/Copd.S124750  0.328
2017 Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, ... ... MacNee W, et al. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics. PMID 28166215 DOI: 10.1038/Ng.3752  0.399
2017 Chen DL, Cheriyan J, Chilvers E, Choudoury G, Coello C, Connell M, Fisk M, Groves AM, Gunn RN, Holman BF, Hutton BF, Lee S, MacNee W, Mohan D, Parr D, et al. Quantification of Lung PET Images: Challenges and Opportunities. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28082432 DOI: 10.2967/Jnumed.116.184796  0.368
2017 Mohan D, Allinder M, Forman J, Mceniery C, Bolton C, Cockcroft J, Macnee W, Fuld J, Gale N, Fisk M, Cheriyan J, Lomas D, Calverley P, Miller B, Wilkinson I, et al. Late Breaking Abstract - Co-morbid disease clusters in chronic obstructive pulmonary disease: the ERICA study European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Oa4664  0.307
2017 Buss L, McKeever T, Mohan D, Maki-Petaja K, Forman J, McEniery C, Cheryian J, Gale N, Cockcroft J, Calverley P, MacNee W, Tal-Singer R, Polkey M, Wilkinson I, Bolton C. P94 Cardiorespiratory physiology in patients with copd according to blood eosinophilia: data from the erica cohort Thorax. 72. DOI: 10.1136/Thoraxjnl-2017-210983.236  0.384
2016 MacNee W. Is Chronic Obstructive Pulmonary Disease an Accelerated Aging Disease? Annals of the American Thoracic Society. 13: S429-S437. PMID 28005421 DOI: 10.1513/Annalsats.201602-124Aw  0.412
2016 Parker RA, Weir CJ, Rubio N, Rabinovich R, Pinnock H, Hanley J, McCloughan L, Drost EM, Mantoani LC, MacNee W, McKinstry B. Application of Mixed Effects Limits of Agreement in the Presence of Multiple Sources of Variability: Exemplar from the Comparison of Several Devices to Measure Respiratory Rate in COPD Patients. Plos One. 11: e0168321. PMID 27973556 DOI: 10.1371/Journal.Pone.0168321  0.322
2016 Andrianopoulos V, Celli BR, Franssen FM, Pinto-Plata VM, Calverley PM, Vanfleteren LE, Vogiatzis I, Vestbo J, Agusti A, Bakke PS, Rennard SI, MacNee W, Tal-Singer R, Yates JC, Wouters EF, et al. Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study. Respiratory Medicine. 119: 87-95. PMID 27692154 DOI: 10.1016/J.Rmed.2016.08.023  0.372
2016 Mirsadraee S, Reid JH, Connell M, MacNee W, Hirani N, Murchison JT, van Beek EJ. Dynamic (4D) CT perfusion offers simultaneous functional and anatomical insights into pulmonary embolism resolution. European Journal of Radiology. 85: 1883-90. PMID 27666631 DOI: 10.1016/J.Ejrad.2016.08.018  0.341
2016 Choudhury G, MacNee W. Role of Inflammation and Oxidative Stress in the Pathology of Ageing in COPD: Potential Therapeutic Interventions. Copd. 1-14. PMID 27624918 DOI: 10.1080/15412555.2016.1214948  0.38
2016 Huang JT, Bolton CE, Miller BE, Tal-Singer R, Rabinovich RA, Palmer CN, Thomson NC, MacNee W. Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease. The European Respiratory Journal. PMID 27587547 DOI: 10.1183/13993003.01125-2016  0.338
2016 Bousquet J, Farrell J, Crooks G, Hellings P, Bel EH, Bewick M, Chavannes NH, de Sousa JC, Cruz AA, Haahtela T, Joos G, Khaltaev N, Malva J, Muraro A, Nogues M, ... ... MacNee W, et al. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5). Clinical and Translational Allergy. 6: 29. PMID 27478588 DOI: 10.1186/S13601-016-0116-9  0.319
2016 MacNee W, Murchison JT. Small Airway Disease or Emphysema: Which Is More Important in Lung Function and FEV1 Decline? An Old Story with a New Twist. American Journal of Respiratory and Critical Care Medicine. 194: 129-30. PMID 27420355 DOI: 10.1164/Rccm.201602-0197Ed  0.369
2016 Mantoani LC, Rubio N, McKinstry B, MacNee W, Rabinovich RA. Interventions to modify physical activity in patients with COPD: a systematic review. The European Respiratory Journal. 48: 69-81. PMID 27103381 DOI: 10.1183/13993003.01744-2015  0.329
2016 Rabinovich RA, Miller BE, Wrobel K, Ranjit K, Williams MC, Drost E, Edwards LD, Lomas DA, Rennard SI, Agustí A, Tal-Singer R, Vestbo J, Wouters EF, John M, van Beek EJ, ... ... MacNee W, et al. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD. The European Respiratory Journal. PMID 27009168 DOI: 10.1183/13993003.01824-2015  0.368
2016 Lange P, Halpin DM, O'Donnell DE, MacNee W. Diagnosis, assessment, and phenotyping of COPD: beyond FEV1. International Journal of Chronic Obstructive Pulmonary Disease. 11: 3-12. PMID 26937185 DOI: 10.2147/Copd.S85976  0.37
2016 Putman RK, Hatabu H, Araki T, Gudmundsson G, Gao W, Nishino M, Okajima Y, Dupuis J, Latourelle JC, Cho MH, El-Chemaly S, Coxson HO, Celli BR, Fernandez IE, Zazueta OE, ... ... MacNee W, et al. Association Between Interstitial Lung Abnormalities and All-Cause Mortality. Jama. 315: 672-81. PMID 26881370 DOI: 10.1001/Jama.2016.0518  0.326
2016 Mantoani L, Priori R, Barretto C, Saini P, Klee M, McNarry S, Mullen S, McKinstry B, MacNee W, Rabinovich R. Acceptability and suitability of the use of TracmorD activity monitor in patients with COPD for home coaching – A pilot study European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1894  0.312
2016 Andrianopoulos V, Celli BR, Franssen FME, Pinto-Plata VM, Calverley PMA, Vanfleteren LEGW, Vogiatzis I, Vestbo J, Agusti A, Bakke PS, Rennard SI, MacNee W, Tal-Singer R, Yates JC, Wouters EFM, et al. Exercise-induced oxygen desaturation determinants including pulmonary emphysema in COPD: ECLIPSE data European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1564  0.376
2016 li f, Zhang A, Mills R, Marwick J, Nicol L, Pound J, MacKinnon A, Howie S, Macnee W, Rossi A, Hirani N. P130 Reduced exosomes expression in BAL fluid from fibrotic interstitial lung disease due to blockage of autophagy in alveolar macrophages Qjm: An International Journal of Medicine. 109. DOI: 10.1093/Qjmed/Hcw120.031  0.35
2016 Li F, Zhang A, Mills R, Marwick J, Nicol L, Pound J, MacKinnon A, Howie S, Macnee W, Rossi A, Hirani N. P113 Reduced exosomes expression in BAL fluid from fibrotic interstitial lung disease due to blockage of autophagy in alveolar macrophages Qjm: An International Journal of Medicine. 109. DOI: 10.1093/Qjmed/Hcw120.014  0.363
2015 MacNee W, Fahy J, Nicod L, Kolls J. Purpose of the Conference: 2015 Transatlantic Airway Conference. Annals of the American Thoracic Society. 12: S111. PMID 26595725 DOI: 10.1513/Annalsats.201505-264Aw  0.401
2015 Hardin M, Cho MH, McDonald ML, Wan E, Lomas DA, Coxson HO, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, et al. A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease. The Pharmacogenomics Journal. PMID 26503814 DOI: 10.1038/Tpj.2015.65  0.334
2015 Kendall M, Buckingham S, Ferguson S, MacNee W, Sheikh A, White P, Worth A, Boyd K, Murray SA, Pinnock H. Exploring the concept of need in people with very severe chronic obstructive pulmonary disease: a qualitative study. Bmj Supportive & Palliative Care. PMID 26310525 DOI: 10.1136/Bmjspcare-2015-000904  0.315
2015 Rabinovich RA, MacNee W. Should we treat chronic obstructive pulmonary disease as a cardiovascular disease? Expert Review of Respiratory Medicine. 9: 459-72. PMID 26190174 DOI: 10.1586/17476348.2015.1070099  0.395
2015 Agustí A, Rennard S, Edwards LD, MacNee W, Wouters E, Miller B, Tal-Singer R, Mullerova H, Celli B. Clinical and prognostic heterogeneity of C and D GOLD groups. The European Respiratory Journal. 46: 250-4. PMID 26130780 DOI: 10.1183/09031936.00012215  0.338
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 159-72. PMID 26028628 DOI: 10.1183/16000617.00000315  0.316
2015 Buckingham S, Kendall M, Ferguson S, MacNee W, Sheikh A, White P, Worth A, Boyd K, Murray SA, Pinnock H. HELPing older people with very severe chronic obstructive pulmonary disease (HELP-COPD): mixed-method feasibility pilot randomised controlled trial of a novel intervention. Npj Primary Care Respiratory Medicine. 25: 15020. PMID 26028347 DOI: 10.1038/Npjpcrm.2015.20  0.354
2015 Sun XJ, Li ZH, Zhang Y, Zhou G, Zhang JQ, Deng JM, Bai J, Liu GN, Li MH, MacNee W, Zhong XN, He ZY. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR protein. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00292.2014. PMID 25957293 DOI: 10.1152/Ajplung.00292.2014  0.382
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 191: e4-e27. PMID 25830527 DOI: 10.1164/Rccm.201501-0044St  0.35
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. The European Respiratory Journal. 45: 879-905. PMID 25829431 DOI: 10.1183/09031936.00009015  0.316
2015 Rennard SI, Locantore N, Delafont B, Tal-Singer R, Silverman EK, Vestbo J, Miller BE, Bakke P, Celli B, Calverley PM, Coxson H, Crim C, Edwards LD, Lomas DA, MacNee W, et al. Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Annals of the American Thoracic Society. 12: 303-12. PMID 25642832 DOI: 10.1513/Annalsats.201403-125Oc  0.396
2015 Rabinovich RA, Drost E, Manning JR, Dunbar DR, Díaz-Ramos M, Lakhdar R, Bastos R, MacNee W. Genome-wide mRNA expression profiling in vastus lateralis of COPD patients with low and normal fat free mass index and healthy controls. Respiratory Research. 16: 1. PMID 25567521 DOI: 10.1186/S12931-014-0139-5  0.325
2015 Lakhdar R, Drost E, MacNee W, Rabinovich R. Apoptosis invastus lateralismuscle of patients with COPD European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa4895  0.315
2015 Wong J, Vesey A, Ferguson S, Fletcher A, Clark T, Connell M, Whitcher B, Kilty I, Vennart W, Beek EJRV, MacNee W, Choudhury G. 18F-Fluorodeoxyglucose (18FDG) PET pulmonary imaging: Role in detecting vascular inflammation European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Oa4989  0.39
2015 Fisk M, Gale N, Mohan D, McEniery C, Forman J, Bolton C, MacNee W, Cockcroft J, Fuld J, Calverley P, Cheriyan J, Tal-Singer R, Polkey M, Wilkinson I. S124 The BODE Index is an independent determinant of arterial stiffness in Chronic Obstructive Pulmonary Disease (COPD) Thorax. 70. DOI: 10.1136/Thoraxjnl-2015-207770.130  0.373
2015 Fisk M, Gale N, Mohan D, McEniery CM, Forman J, Bolton CE, MacNee W, Cockcroft JR, Cheriyan J, Tal-Singer R, Polkey MI, Wilkinson IB. The BODE Index prognostic score is an independent determinant of arterial stiffness in Chronic Obstructive Pulmonary Disease (COPD) Artery Research. 12: 40-40. DOI: 10.1016/J.Artres.2015.10.007  0.385
2014 Hanson C, Sayles H, Rutten EEPA, Wouters EFM, MacNee W, Calverley P, Meza JL, Rennard S. The Association Between Dietary Intake and Phenotypical Characteristics of COPD in the ECLIPSE Cohort. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 1: 115-124. PMID 28848815 DOI: 10.15326/Jcopdf.1.1.2014.0113  0.324
2014 MacNee W, Rabinovich RA, Choudhury G. Ageing and the border between health and disease. The European Respiratory Journal. 44: 1332-52. PMID 25323246 DOI: 10.1183/09031936.00134014  0.38
2014 Diaz AA, Zhou L, Young TP, McDonald ML, Harmouche R, Ross JC, San Jose Estepar R, Wouters EF, Coxson HO, MacNee W, Rennard S, Maltais F, Kinney GL, Hokanson JE, Washko GR, et al. Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers. Academic Radiology. 21: 1255-61. PMID 25088837 DOI: 10.1016/J.Acra.2014.05.013  0.323
2014 Chaudhuri R, McSharry C, Brady J, Grierson C, Messow CM, Spears M, Miele G, Nocka K, MacNee W, Connell M, Murchison JT, Sproule M, Hilmi OJ, Miller DK, Thomson NC. Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma. The European Respiratory Journal. 44: 895-904. PMID 24993912 DOI: 10.1183/09031936.00047014  0.324
2014 Bousquet J, Addis A, Adcock I, Agache I, Agusti A, Alonso A, Annesi-Maesano I, Anto JM, Bachert C, Baena-Cagnani CE, Bai C, Baigenzhin A, ... ... MacNee W, et al. Integrated care pathways for airway diseases (AIRWAYS-ICPs). The European Respiratory Journal. 44: 304-23. PMID 24925919 DOI: 10.1183/09031936.00014614  0.327
2014 Mohan D, Gale NS, McEniery CM, Bolton CE, Cockcroft JR, MacNee W, Fuld J, Lomas DA, Calverley PM, Shale DJ, Miller BE, Wilkinson IB, Tal-Singer R, Polkey MI. Evaluating the role of inflammation in chronic airways disease: the ERICA study. Copd. 11: 552-9. PMID 24832197 DOI: 10.3109/15412555.2014.898031  0.358
2014 McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, et al. Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 51: 678-87. PMID 24825563 DOI: 10.1165/Rcmb.2014-0135Oc  0.339
2014 McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, ... Macnee W, et al. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Annals of the American Thoracic Society. 11: 326-34. PMID 24558953 DOI: 10.1513/Annalsats.201307-229Oc  0.316
2014 Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, et al. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. American Journal of Respiratory and Critical Care Medicine. 189: 1022-30. PMID 24552242 DOI: 10.1164/Rccm.201311-2006Pp  0.4
2014 Choudhury G, Rabinovich R, MacNee W. Comorbidities and systemic effects of chronic obstructive pulmonary disease. Clinics in Chest Medicine. 35: 101-30. PMID 24507840 DOI: 10.1016/J.Ccm.2013.10.007  0.416
2014 Williams MC, Murchison JT, Edwards LD, Agustí A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Vestbo J, ... ... MacNee W, et al. Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality. Thorax. 69: 718-23. PMID 24473329 DOI: 10.1136/Thoraxjnl-2012-203151  0.304
2014 Faner R, Tal-Singer R, Riley JH, Celli B, Vestbo J, MacNee W, Bakke P, Calverley PM, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, Miller BE, Rennard SI, et al. Lessons from ECLIPSE: a review of COPD biomarkers. Thorax. 69: 666-72. PMID 24310110 DOI: 10.1136/Thoraxjnl-2013-204778  0.367
2014 Rabinovich RA, Miller BE, Wrobel K, Choudhury G, Ranjit K, Drost EM, Edwards LD, Lomas DA, Rennard SI, Agusti A, Tal-Singer R, Vestbo J, Wouters E, Beek EV, Murchison JT, ... MacNee W, et al. S51 Circulating Desmosine Relates To Cardiovascular Comorbidity, Coronary Artery Calcification Score (cacs), Systemic Inflammation And Mortality In Patients With Copd Thorax. 69: A28-A29. DOI: 10.1136/Thoraxjnl-2014-206260.57  0.349
2014 Rabinovich RA, Choudhury G, Lahkdar R, Drost EM, McGlynn L, Bai J, Shiels PG, Miller BE, Tal-Singer R, Agusti A, MacNee W. S49 Telomere Attrition In Circulating White Blood Cells In Copd Relates To Lung Function And Outcomes Thorax. 69: A28-A28. DOI: 10.1136/Thoraxjnl-2014-206260.55  0.315
2014 Choudhury G, Fletcher A, Connell M, Whitcher B, Fergusson S, Clark T, Vennart B, Kilty I, VanBeek E, MacNee W. S20 18f-fluorodeoxyglucose (18fdg) Pet Pulmonary Imaging: Comparative Methodology In Copd Patients Thorax. 69: A13-A13. DOI: 10.1136/Thoraxjnl-2014-206260.26  0.312
2014 Kendall M, Buckingham S, Ferguson S, Sheikh A, Murray S, MacNee W, White P, Worth A, Boyd K, Pinnock H. HELPING PEOPLE WITH VERY SEVERE COPD: FEASIBILITY STUDY OF A NOVEL HOLISTIC INTERVENTION Bmj Supportive & Palliative Care. 4: A9.1-A9. DOI: 10.1136/Bmjspcare-2014-000654.23  0.308
2014 Kendall M, Buckingham S, Ferguson S, Sheikh A, Murray S, Boyd K, Pinnock H, MacNee W, Worth A, White P. Helping People With Very Severe Copd: Feasibility Study Of A Novel Community-Based Holistic Intervention Bmj. 4: 106-107. DOI: 10.1136/Bmjspcare-2014-000653.5  0.316
2014 Fisk M, Mohan D, Bolton C, Cockcroft J, MacNee W, McEniery C, Tal-Singer R, Polkey M, Wilkinson I. Aortic stiffness is associated with functional limitation (or six minute walk distance) in chronic obstructive pulmonary disease: the ERICA study Artery Research. 8: 149-149. DOI: 10.1016/J.Artres.2014.09.166  0.383
2013 Coxson HO, Dirksen A, Edwards LD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Crim C, Duvoix A, Fauerbach PN, Lomas DA, Macnee W, Mayer RJ, Miller BE, et al. The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study. The Lancet. Respiratory Medicine. 1: 129-36. PMID 24429093 DOI: 10.1016/S2213-2600(13)70006-7  0.373
2013 MacNee W, Fahy J, Nicod L, Wanner A. Purpose of the conference. Annals of the American Thoracic Society. 10: S107. PMID 24313758 DOI: 10.1513/Annalsats.201307-233Aw  0.303
2013 Romme EA, McAllister DA, Murchison JT, Van Beek EJ, Petrides GS, Price CO, Rutten EP, Smeenk FW, Wouters EF, MacNee W. Associations between COPD related manifestations: a cross-sectional study. Respiratory Research. 14: 129. PMID 24251912 DOI: 10.1186/1465-9921-14-129  0.316
2013 Rutten EP, Calverley PM, Casaburi R, Agusti A, Bakke P, Celli B, Coxson HO, Crim C, Lomas DA, Macnee W, Miller BE, Rennard SI, Scanlon PD, Silverman EK, Tal-Singer R, et al. Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes? Annals of Nutrition & Metabolism. 63: 239-47. PMID 24216978 DOI: 10.1159/000353211  0.383
2013 Dirksen A, MacNee W. The search for distinct and clinically useful phenotypes in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 1045-6. PMID 24180437 DOI: 10.1164/Rccm.201309-1649Ed  0.383
2013 Brittan M, Hoogenboom MM, Padfield GJ, Tura O, Fujisawa T, Maclay JD, Macnee W, Mills NL. Endothelial progenitor cells in patients with chronic obstructive pulmonary disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L964-9. PMID 24142520 DOI: 10.1152/Ajplung.00183.2013  0.357
2013 Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustí A, Fabbri LM, ... ... MacNee W, et al. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 948-57. PMID 23947473 DOI: 10.1164/Rccm.201302-0247Oc  0.396
2013 Thomson NC, Chaudhuri R, Messow CM, Spears M, MacNee W, Connell M, Murchison JT, Sproule M, McSharry C. Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma. Respiratory Medicine. 107: 1501-8. PMID 23927851 DOI: 10.1016/J.Rmed.2013.07.017  0.311
2013 McAllister DA, Morling JR, Fischbacher CM, MacNee W, Wild SH. Socioeconomic deprivation increases the effect of winter on admissions to hospital with COPD: retrospective analysis of 10 years of national hospitalisation data. Primary Care Respiratory Journal : Journal of the General Practice Airways Group. 22: 296-9. PMID 23820514 DOI: 10.4104/Pcrj.2013.00066  0.325
2013 Miller J, Edwards LD, Agustí A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Vestbo J, Wouters E, ... ... Macnee W, et al. Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. Respiratory Medicine. 107: 1376-84. PMID 23791463 DOI: 10.1016/J.Rmed.2013.05.001  0.32
2013 Agusti A, Edwards LD, Celli B, Macnee W, Calverley PM, Müllerova H, Lomas DA, Wouters E, Bakke P, Rennard S, Crim C, Miller BE, Coxson HO, Yates JC, Tal-Singer R, et al. Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort. The European Respiratory Journal. 42: 636-46. PMID 23766334 DOI: 10.1183/09031936.00195212  0.325
2013 Agusti A, MacNee W. Authors response. The chronic obstructive pulmonary disease (COPD) control panel: towards personalised medicine in COPD. Thorax. 68: 389-90. PMID 23593649 DOI: 10.1136/Thoraxjnl-2012-203090  0.339
2013 MacNee W, Allan RJ, Jones I, De Salvo MC, Tan LF. Efficacy and safety of the oral p38 inhibitor PH-797804 in chronic obstructive pulmonary disease: a randomised clinical trial. Thorax. 68: 738-45. PMID 23539534 DOI: 10.1136/Thoraxjnl-2012-202744  0.422
2013 Maclay JD, MacNee W. Cardiovascular disease in COPD: mechanisms. Chest. 143: 798-807. PMID 23460157 DOI: 10.1378/Chest.12-0938  0.342
2013 Rabinovich RA, Louvaris Z, Raste Y, Langer D, Van Remoortel H, Giavedoni S, Burtin C, Regueiro EM, Vogiatzis I, Hopkinson NS, Polkey MI, Wilson FJ, Macnee W, Westerterp KR, Troosters T, et al. Validity of physical activity monitors during daily life in patients with COPD. The European Respiratory Journal. 42: 1205-15. PMID 23397303 DOI: 10.1183/09031936.00134312  0.345
2013 Romme EA, Murchison JT, Edwards LD, van Beek E, Murchison DM, Rutten EP, Smeenk FW, Williams MC, Wouters EF, MacNee W. CT-measured bone attenuation in patients with chronic obstructive pulmonary disease: relation to clinical features and outcomes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1369-77. PMID 23361992 DOI: 10.1002/Jbmr.1873  0.327
2013 Sin DD, MacNee W. Chronic obstructive pulmonary disease and cardiovascular diseases: a "vulnerable" relationship. American Journal of Respiratory and Critical Care Medicine. 187: 2-4. PMID 23281347 DOI: 10.1164/Rccm.201210-1953Ed  0.378
2013 Polkey MI, Spruit MA, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agustí A, Bakke PS, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, et al. Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. American Journal of Respiratory and Critical Care Medicine. 187: 382-6. PMID 23262518 DOI: 10.1164/Rccm.201209-1596Oc  0.375
2013 Agusti A, MacNee W. The COPD control panel: towards personalised medicine in COPD. Thorax. 68: 687-90. PMID 23117977 DOI: 10.1136/Thoraxjnl-2012-202772  0.409
2013 MacNee W. Systemic inflammatory biomarkers and co-morbidities of chronic obstructive pulmonary disease. Annals of Medicine. 45: 291-300. PMID 23110517 DOI: 10.3109/07853890.2012.732703  0.422
2013 Pinnock H, McCloughan L, Todd A, Hanley J, Lewis S, Krishan A, MacNee W, Plagiari C, Sheikh A, McKinstry B. Clinical effectiveness and service implications of telemonitoring for chronic obstructive pulmonary disease: the TELESCOT COPD randomised controlled trial International Journal of Integrated Care. 13. DOI: 10.5334/Ijic.1420  0.364
2013 Fisk M, Gale N, Mohan D, Marchong MN, Forman J, Lomas DA, Cockcroft JR, Bolton CE, MacNee W, Fuld J, Calverley CM, McEniery CM, Tal-Singer R, Wilkinson IB, Polkey MI. Skeletal Muscle Weakness, Not Arterial Stiffness, Differs According to Gold Group in Copd Thorax. 68. DOI: 10.1136/Thoraxjnl-2013-204457.279  0.308
2012 Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustí A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, et al. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 186: 1238-47. PMID 23144326 DOI: 10.1164/Rccm.201206-1013Oc  0.38
2012 Ubhi BK, Cheng KK, Dong J, Janowitz T, Jodrell D, Tal-Singer R, MacNee W, Lomas DA, Riley JH, Griffin JL, Connor SC. Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Molecular Biosystems. 8: 3125-33. PMID 23051772 DOI: 10.1039/C2Mb25194A  0.374
2012 Albert P, Agusti A, Edwards L, Tal-Singer R, Yates J, Bakke P, Celli BR, Coxson HO, Crim C, Lomas DA, Macnee W, Miller B, Rennard S, Silverman EK, Vestbo J, et al. Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax. 67: 701-8. PMID 22696176 DOI: 10.1136/Thoraxjnl-2011-201458  0.426
2012 Romme EA, Murchison JT, Phang KF, Jansen FH, Rutten EP, Wouters EF, Smeenk FW, Van Beek EJ, Macnee W. Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 2338-43. PMID 22692725 DOI: 10.1002/Jbmr.1678  0.327
2012 Agustí A, Edwards LD, Rennard SI, MacNee W, Tal-Singer R, Miller BE, Vestbo J, Lomas DA, Calverley PM, Wouters E, Crim C, Yates JC, Silverman EK, Coxson HO, Bakke P, et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. Plos One. 7: e37483. PMID 22624038 DOI: 10.1371/Journal.Pone.0037483  0.367
2012 Faner R, Rojas M, Macnee W, Agustí A. Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 186: 306-13. PMID 22582162 DOI: 10.1164/Rccm.201202-0282Pp  0.424
2012 Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, ... ... MacNee W, et al. A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. Copd. 9: 151-9. PMID 22429093 DOI: 10.3109/15412555.2012.654923  0.319
2012 Celli BR, Locantore N, Yates J, Tal-Singer R, Miller BE, Bakke P, Calverley P, Coxson H, Crim C, Edwards LD, Lomas DA, Duvoix A, MacNee W, Rennard S, Silverman E, et al. Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 185: 1065-72. PMID 22427534 DOI: 10.1164/Rccm.201110-1792Oc  0.329
2012 Maclay JD, McAllister DA, Rabinovich R, Haq I, Maxwell S, Hartland S, Connell M, Murchison JT, van Beek EJ, Gray RD, Mills NL, Macnee W. Systemic elastin degradation in chronic obstructive pulmonary disease. Thorax. 67: 606-12. PMID 22374923 DOI: 10.1136/Thoraxjnl-2011-200949  0.404
2012 Rahman I, MacNee W. Antioxidant pharmacological therapies for COPD. Current Opinion in Pharmacology. 12: 256-65. PMID 22349417 DOI: 10.1016/J.Coph.2012.01.015  0.575
2012 McAllister DA, Maclay JD, Mills NL, Leitch A, Reid P, Carruthers R, O'Connor J, McAlpine L, Chalmers G, Newby DE, Clark E, Macfarlane PW, Macnee W. Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD. The European Respiratory Journal. 39: 1097-103. PMID 22323574 DOI: 10.1183/09031936.00124811  0.315
2012 Chaudhuri R, McSharry C, Brady J, Donnelly I, Grierson C, McGuinness S, Jolly L, Weir CJ, Messow CM, Spears M, Miele G, Nocka K, Crowther D, Thompson J, Brannigan M, ... ... Macnee W, et al. Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity. The Journal of Allergy and Clinical Immunology. 129: 655-663.e8. PMID 22305682 DOI: 10.1016/J.Jaci.2011.12.996  0.365
2012 Maio S, Sherrill DL, MacNee W, Lange P, Costabel U, Dahlén SE, Sybrecht GW, Burghuber OC, Stevenson R, Tønnesen P, Haeussinger K, Hedlin G, Bauer TT, Riedler J, Nicod L, et al. The European Respiratory Society spirometry tent: a unique form of screening for airway obstruction. The European Respiratory Journal. 39: 1458-67. PMID 22267757 DOI: 10.1183/09031936.00111910  0.392
2012 Ubhi BK, Riley JH, Shaw PA, Lomas DA, Tal-Singer R, MacNee W, Griffin JL, Connor SC. Metabolic profiling detects biomarkers of protein degradation in COPD patients. The European Respiratory Journal. 40: 345-55. PMID 22183483 DOI: 10.1183/09031936.00112411  0.352
2012 Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, ... ... MacNee W, et al. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Human Molecular Genetics. 21: 947-57. PMID 22080838 DOI: 10.1093/Hmg/Ddr524  0.312
2012 Doehner W, Haeusler KG, Endres M, Anker SD, MacNee W, Lainscak M. Neurological and endocrinological disorders: orphans in chronic obstructive pulmonary disease. Respiratory Medicine. S12-9. PMID 22015080 DOI: 10.1016/S0954-6111(11)70005-1  0.363
2012 Cho WS, Duffin R, Bradley M, Megson IL, Macnee W, Howie SE, Donaldson K. NiO and Co3O4 nanoparticles induce lung DTH-like responses and alveolar lipoproteinosis. The European Respiratory Journal. 39: 546-57. PMID 21828028 DOI: 10.1183/09031936.00047111  0.334
2012 Spruit MA, Polkey MI, Celli B, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agusti A, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, et al. Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. Journal of the American Medical Directors Association. 13: 291-7. PMID 21778120 DOI: 10.1016/J.Jamda.2011.06.009  0.374
2012 Cho WS, Duffin R, Poland CA, Duschl A, Oostingh GJ, Macnee W, Bradley M, Megson IL, Donaldson K. Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs. Nanotoxicology. 6: 22-35. PMID 21332300 DOI: 10.3109/17435390.2011.552810  0.331
2011 Vestbo J, Edwards LD, Scanlon PD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, MacNee W, Miller BE, Silverman EK, Tal-Singer R, et al. Changes in forced expiratory volume in 1 second over time in COPD. The New England Journal of Medicine. 365: 1184-92. PMID 21991892 DOI: 10.1056/Nejmoa1105482  0.373
2011 Cho WS, Duffin R, Howie SE, Scotton CJ, Wallace WA, Macnee W, Bradley M, Megson IL, Donaldson K. Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes. Particle and Fibre Toxicology. 8: 27. PMID 21896169 DOI: 10.1186/1743-8977-8-27  0.311
2011 Bathoorn E, Daly P, Gaiser B, Sternad K, Poland C, Macnee W, Drost EM. Cytotoxicity and induction of inflammation by pepsin in Acid in bronchial epithelial cells International Journal of Inflammation. 2011: 569416-569416. PMID 21785693 DOI: 10.4061/2011/569416  0.344
2011 Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK, Coxson H, Edwards L, Knobil K, ... MacNee W, et al. Genome-wide association study of smoking behaviours in patients with COPD Thorax. 66: 894-902. PMID 21685187 DOI: 10.1136/Thoraxjnl-2011-200154  0.334
2011 Maclay JD, McAllister DA, Johnston S, Raftis J, McGuinnes C, Deans A, Newby DE, Mills NL, MacNee W. Increased platelet activation in patients with stable and acute exacerbation of COPD. Thorax. 66: 769-74. PMID 21507906 DOI: 10.1136/Thx.2010.157529  0.405
2011 McAllister DA, MacNee W, Duprez D, Hoffman EA, Vogel-Claussen J, Criqui MH, Budoff M, Jiang R, Bluemke DA, Barr RG. Pulmonary function is associated with distal aortic calcium, not proximal aortic distensibility. MESA lung study. Copd. 8: 71-8. PMID 21495835 DOI: 10.3109/15412555.2011.558543  0.312
2011 Rabinovich RA, MacNee W. Chronic obstructive pulmonary disease and its comorbidities. British Journal of Hospital Medicine. 72: 137-145. PMID 21475093 DOI: 10.12968/Hmed.2011.72.3.137  0.392
2011 MacNee W, Rennard SI, Hunt JF, Edwards LD, Miller BE, Locantore NW, Tal-Singer R. Evaluation of exhaled breath condensate pH as a biomarker for COPD Respiratory Medicine. 105: 1037-1045. PMID 21377342 DOI: 10.1016/J.Rmed.2011.02.009  0.318
2011 Pinnock H, Kendall M, Murray SA, Worth A, Levack P, Porter M, MacNee W, Sheikh A. Living and dying with severe chronic obstructive pulmonary disease: Multi-perspective longitudinal qualitative study Bmj. 342: 268. PMID 21262897 DOI: 10.1136/Bmj.D142  0.315
2011 Sin DD, Miller BE, Duvoix A, Man SF, Zhang X, Silverman EK, Connett JE, Anthonisen NA, Wise RA, Tashkin D, Celli BR, Edwards LD, Locantore N, Macnee W, Tal-Singer R, et al. Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 183: 1187-92. PMID 21216880 DOI: 10.1164/Rccm.201008-1220Oc  0.429
2010 He Z, Ou L, Zhang J, Bai J, Liu G, Li M, Deng J, MacNee W, Zhong X. Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease. Respiration. 80: 445-452. PMID 20881376 DOI: 10.1159/000321374  0.431
2010 Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA. Susceptibility to exacerbation in chronic obstructive pulmonary disease. The New England Journal of Medicine. 363: 1128-38. PMID 20843247 DOI: 10.1056/Nejmoa0909883  0.41
2010 Agusti A, Calverley PM, Celli B, Coxson HO, Edwards LD, Lomas DA, MacNee W, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Wouters E, Yates JC, Vestbo J. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respiratory Research. 11: 122. PMID 20831787 DOI: 10.1186/1465-9921-11-122  0.41
2010 Mair G, Maclay J, Miller JJ, McAllister D, Connell M, Murchison JT, MacNee W. Airway dimensions in COPD: relationships with clinical variables. Respiratory Medicine. 104: 1683-90. PMID 20541384 DOI: 10.1016/J.Rmed.2010.04.021  0.346
2010 Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, MacNee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, et al. Chronic obstructive pulmonary disease phenotypes: The future of COPD American Journal of Respiratory and Critical Care Medicine. 182: 598-604. PMID 20522794 DOI: 10.1164/Rccm.200912-1843Cc  0.361
2010 MacNee W. Right heart function in COPD. Seminars in Respiratory and Critical Care Medicine. 31: 295-312. PMID 20496299 DOI: 10.1055/S-0030-1254070  0.392
2010 Marwick JA, Edirisinghe I, Arunachalam G, Stevenson CS, Macnee W, Kirkham PA, Rahman I. Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs. Journal of Inflammation (London, England). 7: 11. PMID 20205917 DOI: 10.1186/1476-9255-7-11  0.528
2010 Haq I, Chappell S, Johnson SR, Lotya J, Daly L, Morgan K, Guetta-Baranes T, Roca J, Rabinovich R, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, et al. Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population. Bmc Medical Genetics. 11: 7. PMID 20078883 DOI: 10.1186/1471-2350-11-7  0.311
2009 MacNee W. Premature vascular ageing in cystic fibrosis. European Respiratory Journal. 34: 1217-1218. PMID 19948908 DOI: 10.1183/09031936.00155209  0.378
2009 Behr J, Demedts M, Buhl R, Costabel U, Dekhuijzen RP, Jansen HM, MacNee W, Thomeer M, Wallaert B, Laurent F, Nicholson AG, Verbeken EK, Verschakelen J, Flower CD, Petruzzelli S, et al. Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial. Respiratory Research. 10: 101. PMID 19860915 DOI: 10.1186/1465-9921-10-101  0.357
2009 Anderson D, MacNee W. Targeted treatment in COPD: a multi-system approach for a multi-system disease. International Journal of Chronic Obstructive Pulmonary Disease. 4: 321-335. PMID 19750192 DOI: 10.2147/Copd.S2999  0.349
2009 MacNee W, Tuder RM. New paradigms in the pathogenesis of chronic obstructive pulmonary disease I. Proceedings of the American Thoracic Society. 6: 527-31. PMID 19741262 DOI: 10.1513/pats.200905-027DS  0.328
2009 MacNee W. Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD) Biochemical Society Transactions. 37: 819-823. PMID 19614601 DOI: 10.1042/Bst0370819  0.452
2009 Maclay JD, McAllister DA, Mills NL, Paterson FP, Ludlam CA, Drost EM, Newby DE, Macnee W. Vascular dysfunction in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 180: 513-20. PMID 19542477 DOI: 10.1164/Rccm.200903-0414Oc  0.417
2009 Maclay JD, Rabinovich RA, MacNee W. Update in chronic obstructive pulmonary disease 2008. American Journal of Respiratory and Critical Care Medicine. 179: 533-41. PMID 19318543 DOI: 10.1164/Rccm.200901-0134Up  0.412
2009 Lu S, Duffin R, Poland C, Daly P, Murphy F, Drost E, MacNee W, Stone V, Donaldson K. Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environmental Health Perspectives. 117: 241-247. PMID 19270794 DOI: 10.1289/Ehp.11811  0.332
2009 Mills NL, Donaldson K, Hadoke PW, Boon NA, MacNee W, Cassee FR, Sandström T, Blomberg A, Newby DE. Adverse cardiovascular effects of air pollution Nature Reviews Cardiology. 6: 36-44. PMID 19029991 DOI: 10.1038/Ncpcardio1399  0.341
2009 Macnee W, Maclay J, McAllister D. Cardiovascular injury and repair in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 5: 824-33. PMID 19017737 DOI: 10.1513/pats.200807-071TH  0.321
2009 Schünemann HJ, Woodhead M, Anzueto A, Buist S, MacNee W, Rabe KF, Heffner J. A vision statement on guideline development for respiratory disease: the example of COPD The Lancet. 373: 774-779. PMID 18835641 DOI: 10.1016/S0140-6736(08)61347-1  0.329
2009 Mair G, Miller JJ, McAllister D, Maclay J, Connell M, Murchison JT, MacNee W. Computed tomographic emphysema distribution: relationship to clinical features in a cohort of smokers European Respiratory Journal. 33: 536-542. PMID 18829675 DOI: 10.1183/09031936.00111808  0.339
2008 Bathoorn E, Kerstjens H, Postma D, Timens W, MacNee W. Airways inflammation and treatment during acute exacerbations of COPD. International Journal of Chronic Obstructive Pulmonary Disease. 3: 217-229. PMID 18686731 DOI: 10.2147/Copd.S1210  0.405
2008 Chappell S, Daly L, Morgan K, Guetta-Baranes T, Roca J, Rabinovich R, Lotya J, Millar AB, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, et al. Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD European Respiratory Journal. 32: 931-937. PMID 18614560 DOI: 10.1183/09031936.00065308  0.407
2008 MacNee W. Update in chronic obstructive pulmonary disease 2007. American Journal of Respiratory and Critical Care Medicine. 177: 820-829. PMID 18390963 DOI: 10.1164/Rccm.200801-167Up  0.4
2008 Cazzola M, MacNee W, Martinez FJ, Rabe KF, Franciosi LG, Barnes PJ, Brusasco V, Burge PS, Calverley PM, Celli BR, Jones PW, Mahler DA, Make B, Miravitlles M, Page CP, et al. Outcomes for COPD pharmacological trials: from lung function to biomarkers. The European Respiratory Journal. 31: 416-69. PMID 18238951 DOI: 10.1183/09031936.00099306  0.348
2008 Vestbo J, Anderson W, Coxson HO, Crim C, Dawber F, Edwards L, Hagan G, Knobil K, Lomas DA, MacNee W, Silverman EK, Tal-Singer R. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE). European Respiratory Journal. 31: 869-873. PMID 18216052 DOI: 10.1183/09031936.00111707  0.409
2008 Mills NL, Miller JJ, Anand A, Robinson SD, Frazer GA, Anderson D, Breen L, Wilkinson IB, McEniery CM, Donaldson K, Newby DE, Macnee W. Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk. Thorax. 63: 306-11. PMID 18024535 DOI: 10.1136/Thx.2007.083493  0.373
2008 Arestis NJ, MacNee W, Wightman AJA, Murchison JT. Takayasu Arteritis with predominantly pulmonary involvement diagnosed by CT angiography Respiratory Medicine Cme. 1: 278-280. DOI: 10.1016/J.Rmedc.2008.07.002  0.308
2008 MacNee W. Oxidants/antioxidants and chronic obstructive pulmonary disease: pathogenesis to therapy. Novartis Foundation Symposium. 234: 169-188. DOI: 10.1002/0470868678.Ch11  0.422
2007 Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra PS, Miniati M, Monti S, O'Connor CM, et al. Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD. European Respiratory Journal. 30: 810-812. PMID 17906092 DOI: 10.1183/09031936.00057107  0.374
2007 McAllister DA, Maclay JD, Mills NL, Mair G, Miller J, Anderson D, Newby DE, Murchison JT, Macnee W. Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 176: 1208-14. PMID 17885263 DOI: 10.1164/Rccm.200707-1080Oc  0.39
2007 Maclay JD, McAllister DA, Macnee W. Cardiovascular risk in chronic obstructive pulmonary disease. Respirology (Carlton, Vic.). 12: 634-41. PMID 17875049 DOI: 10.1111/J.1440-1843.2007.01136.X  0.4
2007 MacNee W. Pathogenesis of chronic obstructive pulmonary disease. Clinics in Chest Medicine. 28: 479-513. PMID 17720039 DOI: 10.1016/J.Ccm.2007.06.008  0.454
2006 MacNee W, Viegi G, Kamel N. New opportunities for respiratory research in Europe: FP7 European Respiratory Journal. 29: 223-225. PMID 17264318 DOI: 10.1183/09031936.00159006  0.347
2006 Morrison D, Rahman I, MacNee W. Permeability, inflammation and oxidant status in airspace epithelium exposed to ozone. Respiratory Medicine. 100: 2227-34. PMID 17023150 DOI: 10.1016/J.Rmed.2005.10.005  0.531
2006 Roghanian A, Drost EM, MacNee W, Howie SEM, Sallenave J. Inflammatory Lung Secretions Inhibit Dendritic Cell Maturation and Function via Neutrophil Elastase American Journal of Respiratory and Critical Care Medicine. 174: 1189-1198. PMID 16959917 DOI: 10.1164/Rccm.200605-632Oc  0.361
2006 Szulakowski P, Mróz RM, Pierzchała W, Chyczewska E, MacNee W. [Pathogenesis of chronic obstructive pulmonary disease. Molecular mechanisms (part II)]. Wiadomosci Lekarskie (Warsaw, Poland : 1960). 59: 250-4. PMID 16813274  0.32
2006 Szulakowski P, Crowther AJ, Jiménez LA, Donaldson K, Mayer R, Leonard TB, MacNee W, Drost EM. The effect of smoking on the transcriptional regulation of lung inflammation in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 174: 41-50. PMID 16574938 DOI: 10.1164/Rccm.200505-725Oc  0.437
2006 Morlá M, Busquets X, Pons J, Sauleda J, MacNee W, Agustí AGN. Telomere shortening in smokers with and without COPD. European Respiratory Journal. 27: 525-528. PMID 16507852 DOI: 10.1183/09031936.06.00087005  0.386
2006 Similowski T, Agustí A, MacNee W, Schönhofer B. The potential impact of anaemia of chronic disease in COPD European Respiratory Journal. 27: 390-396. PMID 16452598 DOI: 10.1183/09031936.06.00143704  0.42
2006 Marwick JA, Stevenson CS, Giddings J, MacNee W, Butler K, Rahman I, Kirkham PA. Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L897-908. PMID 16361360 DOI: 10.1152/Ajplung.00116.2005  0.548
2006 Chappell S, Daly L, Morgan K, Guetta Baranes T, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, MacNee W, Stolk J, Hiemstra P, Miniati M, Monti S, O'Connor CM, et al. Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease. Human Mutation. 27: 103-9. PMID 16278826 DOI: 10.1002/Humu.20275  0.379
2006 MacNee W. Pathogenesis of chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 2: 258-66; discussion 2. PMID 16267346 DOI: 10.1513/pats.200504-045SR  0.336
2006 Drost EM, Poland CA, Donaldson K, MacNee W. Diminished peroxisome proliferator-activated receptor (PPAR) regulation as a potential mechanism for the persistent inflammation in chronic obstructive pulmonary disease European Respiratory Review. 15: 211-212. DOI: 10.1183/09059180.00010124  0.414
2006 MacNee W. Pathology, pathogenesis, and pathophysiology Bmj. 332: 1202-1204. DOI: 10.1136/Bmj.332.7551.1202  0.466
2006 Morla M, Busquets X, Pons J, Sauleda J, Macnee W, Agusti AG. Telomere shortening in smokers with and without COPD: Eur Respir J 2006;27:525–8 Respiratory Medicine: Copd Update. 1: 140. DOI: 10.1016/J.Rmedu.2006.03.022  0.338
2006 Celli B, Calverley P, Rennard S, Wouters E, Agusti A, Anthonisen N, Macnee W, Jones P, Pride N, Rodriguez-Roisin R, Rossi A, Wanner A. Proposal for a multidimensional staging system for chronic obstructive pulmonary disease Respiratory Medicine: Copd Update. 1: 139. DOI: 10.1016/J.Rmedu.2006.03.018  0.373
2006 Chappell S, Daly L, Morgan K, Baranes TG, Roca J, Rabinovich R, Millar A, Donnelly SC, Keatings V, Macnee W, Stolk J, Hiemstra P, Miniati M, Monti S, O’connor M, et al. Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease: Hum Mutat 2005;27:103–9 Respiratory Medicine: Copd Update. 1: 103-106. DOI: 10.1016/J.Rmedu.2006.01.018  0.362
2005 MacNee W. Oxidants and COPD. Current Drug Targets - Inflammation & Allergy. 4: 627-641. PMID 17305519 DOI: 10.2174/156801005774912815  0.448
2005 Demedts M, Behr J, Buhl R, Costabel U, Dekhuijzen R, Jansen HM, MacNee W, Thomeer M, Wallaert B, Laurent F, Nicholson AG, Verbeken EK, Verschakelen J, Flower CD, Capron F, et al. High-dose acetylcysteine in idiopathic pulmonary fibrosis. The New England Journal of Medicine. 353: 2229-42. PMID 16306520 DOI: 10.1056/Nejmoa042976  0.369
2005 Celli BR, Calverley PM, Rennard SI, Wouters EF, Agusti A, Anthonisen N, Macnee W, Jones P, Pride N, Rodriguez-Roisin R, Rossi A, Wanner A. Proposal for a multidimensional staging system for chronic obstructive pulmonary disease. Respiratory Medicine. 99: 1546-54. PMID 16291077 DOI: 10.1016/J.Rmed.2005.03.019  0.376
2005 Donaldson K, Tran L, Jimenez LA, Duffin R, Newby DE, Mills N, MacNee W, Stone V. Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure. Particle and Fibre Toxicology. 2: 10. PMID 16242040 DOI: 10.1186/1743-8977-2-10  0.336
2005 MacNee W. Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 2: 50-60. PMID 16113469 DOI: 10.1513/pats.200411-056SF  0.337
2005 McNeilly JD, Jiménez LA, Clay MF, MacNee W, Howe A, Heal MR, Beverland IJ, Donaldson K. Soluble transition metals in welding fumes cause inflammation via activation of NF-kappaB and AP-1. Toxicology Letters. 158: 152-7. PMID 16039403 DOI: 10.1016/J.Toxlet.2005.03.005  0.306
2005 Donaldson K, Mills N, MacNee W, Robinson S, Newby D. Role of inflammation in cardiopulmonary health effects of PM. Toxicology and Applied Pharmacology. 207: 483-488. PMID 15979665 DOI: 10.1016/J.Taap.2005.02.020  0.365
2005 Echazarreta AL, Rahman I, Peinado V, Barberà JA, Roca J, MacNee W, Rodríguez-Roisin R. Lack of systemic oxidative stress during PAF challenge in mild asthma. Respiratory Medicine. 99: 519-23. PMID 15823446 DOI: 10.1016/J.Rmed.2004.10.013  0.526
2005 Drost EM, Skwarski KM, Sauleda J, Soler N, Roca J, Agusti A, Macnee W. Oxidative stress and airway inflammation in severe exacerbations of COPD Thorax. 60: 293-300. PMID 15790984 DOI: 10.1136/Thx.2004.027946  0.453
2005 Fabbri L, Peters SP, Pavord I, Wenzel SE, Lazarus SC, MacNee W, Lemaire F, Abraham E. Allergic Rhinitis, Asthma, Airway Biology, and Chronic Obstructive Pulmonary Disease in AJRCCM in 2004 American Journal of Respiratory and Critical Care Medicine. 171: 686-698. PMID 15790866 DOI: 10.1164/Rccm.2412006  0.317
2005 Bradley TD, Miller YE, Martinez FJ, Angus DC, Macnee W, Abraham E. Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders, and sleep-disordered breathing in AJRCCM in 2004. American Journal of Respiratory and Critical Care Medicine. 171: 675-85. PMID 15790865 DOI: 10.1164/Rccm.2412008  0.326
2005 Nemery B, Yew WW, Albert R, Brun-Buisson C, Macnee W, Martinez FJ, Angus DC, Abraham E. Tuberculosis, nontuberculous lung infection, pleural disorders, pulmonary function, respiratory muscles, occupational lung disease, pulmonary infections, and social issues in AJRCCM in 2004. American Journal of Respiratory and Critical Care Medicine. 171: 554-62. PMID 15753485 DOI: 10.1164/Rccm.2412009  0.32
2005 Bush A, Accurso F, Macnee W, Lazarus SC, Abraham E. Cystic fibrosis, pediatrics, control of breathing, pulmonary physiology and anatomy, and surfactant biology in AJRCCM in 2004. American Journal of Respiratory and Critical Care Medicine. 171: 545-53. PMID 15753484 DOI: 10.1164/Rccm.2412007  0.317
2005 Gilmour PS, Morrison ER, Vickers MA, Ford I, Ludlam CA, Greaves M, Donaldson K, Macnee W. The procoagulant potential of environmental particles (PM10) Occupational and Environmental Medicine. 62: 164-171. PMID 15723881 DOI: 10.1136/Oem.2004.014951  0.334
2004 Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, Rahman I. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. American Journal of Respiratory Cell and Molecular Biology. 31: 633-42. PMID 15333327 DOI: 10.1165/Rcmb.2004-0006Oc  0.566
2004 MacNee W. Guidelines for chronic obstructive pulmonary disease. Bmj. 329: 361-363. PMID 15310589 DOI: 10.1136/Bmj.329.7462.361  0.406
2004 Celli BR, MacNee W, Agusti A, Anzueto AR, Berg B, Buist AS, Calverley PMA, Chavannes N, Dillard T, Fahy B, Fein A, Heffner J, Lareau S, Meek P, Martinez F, et al. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper European Respiratory Journal. 23: 932-946. PMID 15219010 DOI: 10.1183/09031936.04.00014304  0.4
2004 Noguera A, Sala E, Pons AR, Iglesias J, MacNee W, Agustí AGN. Expression of Adhesion Molecules During Apoptosis of Circulating Neutrophils in COPD Chest. 125: 1837-1842. PMID 15136398 DOI: 10.1378/Chest.125.5.1837  0.379
2004 Antonicelli F, Brown D, Parmentier M, Drost EM, Hirani N, Rahman I, Donaldson K, MacNee W. Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L1319-27. PMID 15136298 DOI: 10.1152/Ajplung.00329.2003  0.526
2003 Agustí A, MacNee W, Donaldson K, Cosio M. Hypothesis: Does COPD have an autoimmune component? Thorax. 58: 832-834. PMID 14514931 DOI: 10.1136/Thorax.58.10.832  0.456
2003 MacNee W, Donaldson K. Mechanism of lung injury caused by PM10 and ultrafine particles with special reference to COPD The European Respiratory Journal. Supplement. 21. PMID 12762574 DOI: 10.1183/09031936.03.00403203  0.39
2003 Donaldson K, Stone V, Borm PJ, Jimenez LA, Gilmour PS, Schins RP, Knaapen AM, Rahman I, Faux SP, Brown DM, MacNee W. Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radical Biology & Medicine. 34: 1369-82. PMID 12757847 DOI: 10.1016/S0891-5849(03)00150-3  0.546
2003 Wickenden JA, Clarke MC, Rossi AG, Rahman I, Faux SP, Donaldson K, MacNee W. Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis. American Journal of Respiratory Cell and Molecular Biology. 29: 562-70. PMID 12748058 DOI: 10.1165/Rcmb.2002-0235Oc  0.528
2003 MacNee W, Calverley PMA. Chronic obstructive pulmonary disease • 7: Management of COPD Thorax. 58: 261-265. PMID 12612309 DOI: 10.1136/Thorax.58.3.261  0.335
2003 Gilmour PS, Rahman I, Donaldson K, MacNee W. Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L533-40. PMID 12573991 DOI: 10.1152/Ajplung.00277.2002  0.513
2003 Kim H, Liu X, Kobayashi T, Kohyama T, Wen FQ, Romberger DJ, Conner H, Gilmour PS, Donaldson K, MacNee W, Rennard SI. Ultrafine carbon black particles inhibit human lung fibroblast-mediated collagen gel contraction. American Journal of Respiratory Cell and Molecular Biology. 28: 111-21. PMID 12495939 DOI: 10.1165/Rcmb.4796  0.327
2003 MacNee W. COPD: causes and pathology Medicine. 31: 71-75. DOI: 10.1383/Medc.31.12.71.27170  0.42
2002 Marwick JA, Kirkham P, Gilmour PS, Donaldson K, MacNEE W, Rahman I. Cigarette smoke-induced oxidative stress and TGF-beta1 increase p21waf1/cip1 expression in alveolar epithelial cells. Annals of the New York Academy of Sciences. 973: 278-83. PMID 12485877 DOI: 10.1111/J.1749-6632.2002.Tb04649.X  0.535
2002 Rahman I, van Schadewijk AA, Crowther AJ, Hiemstra PS, Stolk J, MacNee W, De Boer WI. 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 166: 490-5. PMID 12186826 DOI: 10.1164/Rccm.2110101  0.614
2002 Rahman I, Gilmour PS, Jimenez LA, MacNee W. Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. Molecular and Cellular Biochemistry. 234: 239-48. PMID 12162440 DOI: 10.1007/978-1-4615-1087-1_28  0.519
2002 Kim HJ, Liu X, Wang H, Kohyama T, Kobayashi T, Wen FQ, Romberger DJ, Abe S, MacNee W, Rahman I, Rennard SI. Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L409-17. PMID 12114203 DOI: 10.1152/Ajplung.00059.2002  0.544
2002 Rahman I, MacNee W. Oxidative stress and adaptive response of glutathione in bronchial epithelial cells. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 32: 486-8. PMID 11972591 DOI: 10.1046/J.0954-7894.2002.01368.X  0.498
2002 Antonicelli F, Parmentier M, Drost EM, Hirani N, Rahman I, Donaldson K, MacNee W. Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells. Free Radical Biology & Medicine. 32: 492-502. PMID 11958950 DOI: 10.1016/S0891-5849(01)00820-6  0.525
2002 Jardine H, MacNee W, Donaldson K, Rahman I. Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. The Journal of Biological Chemistry. 277: 21158-66. PMID 11912197 DOI: 10.1074/Jbc.M112145200  0.512
2002 Drost EM, MacNee W. Potential role of IL-8, platelet-activating factor and TNF-α in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis European Journal of Immunology. 32: 393-403. PMID 11813158 DOI: 10.1002/1521-4141(200202)32:2<393::Aid-Immu393>3.0.Co;2-5  0.365
2002 Jiménez LA, Drost EM, Gilmour PS, Rahman I, Antonicelli F, Ritchie H, MacNee W, Donaldson K. PM(10)-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-alpha. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L237-48. PMID 11792628 DOI: 10.1152/Ajplung.00024.2001  0.51
2002 Gilmour PS, Rahman I, Stone V, Donaldson K, MacNee W. PM 10 -mediated IL-8 Release from Epithelial Cells Involves Histone Acetylation Annals of Occupational Hygiene. 46: 436-439. DOI: 10.1093/Annhyg/46.Suppl_1.436  0.522
2002 Duffin R, Tran CL, Clouter A, Brown DM, MacNee W, Stone V, Donaldson K. The Importance of Surface Area and Specific Reactivity in the Acute Pulmonary Inflammatory Response to Particles Annals of Occupational Hygiene. 46: 242-245. DOI: 10.1093/Annhyg/46.Suppl_1.242  0.307
2001 MacNee W. Airway infection does not accelerate decline in lung function in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 164: 1758-1759. PMID 11734419 DOI: 10.1164/Ajrccm.164.10.2108049B  0.417
2001 MacNee W. Oxidative stress and lung inflammation in airways disease. European Journal of Pharmacology. 429: 195-207. PMID 11698041 DOI: 10.1016/S0014-2999(01)01320-6  0.376
2001 Duffin R, Gilmour PS, Schins RPF, Clouter A, Guy K, Brown DM, MacNee W, Borm PJ, Donaldson K, Stone V. Aluminium Lactate Treatment of DQ12 Quartz Inhibits Its Ability to Cause Inflammation, Chemokine Expression, and Nuclear Factor-κB Activation Toxicology and Applied Pharmacology. 176: 10-17. PMID 11578144 DOI: 10.1006/Taap.2001.9268  0.337
2001 Rahman I, Mulier B, Gilmour PS, Watchorn T, Donaldson K, Jeffery PK, MacNee W. Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB. Biochemical Pharmacology. 62: 787-94. PMID 11551525 DOI: 10.1016/S0006-2952(01)00702-X  0.544
2001 Donaldson K, Stone V, Seaton A, MacNee W. Ambient particle inhalation and the cardiovascular system: potential mechanisms. Environmental Health Perspectives. 109: 523-527. PMID 11544157 DOI: 10.1289/Ehp.01109S4523  0.305
2001 Horváth I, MacNee W, Kelly FJ, Dekhuijzen PNR, Phillips M, Döring G, Choi AMK, Yamaya M, Bach FH, Willis D, Donnelly LE, Chung KF, Barnes PJ. “Haemoxygenase-1 induction and exhaled markers of oxidative stress in lung diseases”, summary of the ERS Research Seminar in Budapest, Hungary, September, 1999 European Respiratory Journal. 18: 420-430. PMID 11529303 DOI: 10.1183/09031936.01.00231201  0.365
2001 Gilmour PS, Rahman I, Hayashi S, Hogg JC, Donaldson K, MacNee W. Adenoviral E1A primes alveolar epithelial cells to PM(10)-induced transcription of interleukin-8. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L598-606. PMID 11504686 DOI: 10.1152/Ajplung.2001.281.3.L598  0.547
2001 Noguera A, Batle S, Miralles C, Iglesias J, Busquets X, MacNee W, Agustí AGN. Enhanced neutrophil response in chronic obstructive pulmonary disease Thorax. 56: 432-437. PMID 11359957 DOI: 10.1136/Thorax.56.6.432  0.442
2001 MacNee W, Rahman I. Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease? Trends in Molecular Medicine. 7: 55-62. PMID 11286755 DOI: 10.1016/S1471-4914(01)01912-8  0.608
2000 MacNee W, Li XY, Gilmour P, Donaldson K. Systemic Effect of Particulate Air Pollution. Inhalation Toxicology. 12: 233-244. PMID 26368621 DOI: 10.1080/08958378.2000.11463218  0.352
2000 Parmentier M, Hirani N, Rahman I, Donaldson K, MacNee W, Antonicelli F. Regulation of lipopolysaccharide-mediated interleukin-1beta release by N-acetylcysteine in THP-1 cells. The European Respiratory Journal. 16: 933-9. PMID 11153595 DOI: 10.1183/09031936.00.16593300  0.498
2000 Skwarska E, Cohen G, Skwarski KM, Lamb C, Bushell D, Parker S, MacNee W. Randomised controlled trial of supported discharge in patients with exacerbations of chronic obstructive pulmonary disease Thorax. 55: 907-912. PMID 11050258 DOI: 10.1136/Thorax.55.11.907  0.345
2000 Rahman I, MacNee W. Oxidative stress and regulation of glutathione in lung inflammation. The European Respiratory Journal. 16: 534-54. PMID 11028671 DOI: 10.1034/J.1399-3003.2000.016003534.X  0.581
2000 Schins RP, McAlinden A, MacNee W, Jimenez LA, Ross JA, Guy K, Faux SP, Donaldson K. Persistent depletion of I kappa B alpha and interleukin-8 expression in human pulmonary epithelial cells exposed to quartz particles. Toxicology and Applied Pharmacology. 167: 107-17. PMID 10964761 DOI: 10.1006/Taap.2000.8982  0.302
2000 Rahman I, MacNee W. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radical Biology & Medicine. 28: 1405-20. PMID 10924859 DOI: 10.1016/S0891-5849(00)00215-X  0.54
2000 Miralles C, Busquets X, Santos C, Togores B, Hussain S, Rahman I, MacNee W, Agustí AG. Regulation of iNOS expression and glutathione levels in rat liver by oxygen tension. Febs Letters. 476: 253-7. PMID 10913623 DOI: 10.1016/S0014-5793(00)01748-8  0.483
2000 Mantle D, Patel VB, Why HJ, Ahmed S, Rahman I, MacNee W, Wassif WS, Richardson PJ, Preedy VR. Effects of lisinopril and amlodipine on antioxidant status in experimental hypertension. Clinica Chimica Acta; International Journal of Clinical Chemistry. 299: 1-10. PMID 10900288 DOI: 10.1016/S0009-8981(00)00270-9  0.475
2000 Jiménez LA, Thompson J, Brown DA, Rahman I, Antonicelli F, Duffin R, Drost EM, Hay RT, Donaldson K, MacNee W. Activation of NF-kappaB by PM(10) occurs via an iron-mediated mechanism in the absence of IkappaB degradation. Toxicology and Applied Pharmacology. 166: 101-10. PMID 10896851 DOI: 10.1006/Taap.2000.8957  0.505
2000 MacNee W. Oxidants/antioxidants and COPD. Chest. 117: 3-3. PMID 10843965 DOI: 10.1378/Chest.117.5_Suppl_1.303S-A  0.382
2000 Rahman I, van Schadewijk AA, Hiemstra PS, Stolk J, van Krieken JH, MacNee W, de Boer WI. Localization of gamma-glutamylcysteine synthetase messenger rna expression in lungs of smokers and patients with chronic obstructive pulmonary disease. Free Radical Biology & Medicine. 28: 920-5. PMID 10802223 DOI: 10.1016/S0891-5849(00)00179-9  0.61
2000 Rahman I, Swarska E, Henry M, Stolk J, MacNee W. Is there any relationship between plasma antioxidant capacity and lung function in smokers and in patients with chronic obstructive pulmonary disease? Thorax. 55: 189-93. PMID 10679536 DOI: 10.1136/Thorax.55.3.189  0.618
1999 Rahman I, MacNee W. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L1067-L1088. PMID 29592056 DOI: 10.1152/ajplung.1999.277.6.L1067  0.568
1999 Rahman I, MacNee W. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. The American Journal of Physiology. 277: L1067-88. PMID 10600876 DOI: 10.1152/Ajplung.1999.277.6.L1067  0.615
1999 Macnee W, Rahman I. Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 160: S58-65. PMID 10556172 DOI: 10.1164/Ajrccm.160.Supplement_1.15  0.59
1999 Li XY, Brown D, Smith S, MacNee W, Donaldson K. Short-Term Inflammatory Responses Following Intratracheal Instillation Of Fine And Ultrafine Carbon Black In Rats Inhalation Toxicology. 11: 709-731. PMID 10477444 DOI: 10.1080/089583799196826  0.304
1999 Rahman I, Skwarska E, Henry M, Davis M, O'Connor CM, FitzGerald MX, Greening A, MacNee W. Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis. Free Radical Biology & Medicine. 27: 60-8. PMID 10443920 DOI: 10.1016/S0891-5849(99)00035-0  0.557
1999 Lapperre TS, Jimenez LA, Antonicelli F, Drost EM, Hiemstra PS, Stolk J, MacNee W, Rahman I. Apocynin increases glutathione synthesis and activates AP-1 in alveolar epithelial cells. Febs Letters. 443: 235-9. PMID 9989612 DOI: 10.1016/S0014-5793(98)01723-2  0.507
1999 Rahman I, Antonicelli F, MacNee W. Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells. The Journal of Biological Chemistry. 274: 5088-96. PMID 9988757 DOI: 10.1074/Jbc.274.8.5088  0.513
1999 Morrison D, Rahman I, Lannan S, MacNee W. Epithelial permeability, inflammation, and oxidant stress in the air spaces of smokers. American Journal of Respiratory and Critical Care Medicine. 159: 473-9. PMID 9927360 DOI: 10.1164/Ajrccm.159.2.9804080  0.553
1999 Morrison D, Strieter RM, Donnelly SC, Burdick MD, Kunkel SL, MacNee W. Neutrophil chemokines in bronchoalveolar lavage fluid and leukocyte-conditioned medium from nonsmokers and smokers. The European Respiratory Journal. 12: 1067-72. PMID 9863998 DOI: 10.1183/09031936.98.12051067  0.335
1999 MacNee W, Donaldson K. Particulate Air Pollution: Injurious and Protective Mechanisms in the Lungs Air Pollution and Health. 653-672. DOI: 10.1016/B978-012352335-8/50105-8  0.356
1998 Rahman I, Bel A, Mulier B, Donaldson K, MacNee W. Differential regulation of glutathione by oxidants and dexamethasone in alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 275: L80-L86. PMID 29592037 DOI: 10.1152/ajplung.1998.275.1.L80  0.456
1998 Stone V, Shaw J, Brown DM, MacNee W, Faux SP, Donaldson K. The role of oxidative stress in the prolonged inhibitory effect of ultrafine carbon black on epithelial cell function. Toxicology in Vitro. 12: 649-659. PMID 20654455 DOI: 10.1016/S0887-2333(98)00050-2  0.318
1998 Skwarski KM, Morrison D, Barratt A, Lee M, MacNee W. Effects of hypoxia on renal hormonal balance in normal subjects and in patients with COPD. Respiratory Medicine. 92: 1331-1336. PMID 10197226 DOI: 10.1016/S0954-6111(98)90138-X  0.335
1998 Noguera A, Busquets X, Sauleda J, Villaverde JM, MacNEE W, Agustí AGN. Expression of Adhesion Molecules and G Proteins in Circulating Neutrophils in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. 158: 1664-1668. PMID 9817722 DOI: 10.1164/Ajrccm.158.5.9712092  0.35
1998 Rahman I, MacNee W. Role of transcription factors in inflammatory lung diseases. Thorax. 53: 601-12. PMID 9797762 DOI: 10.1136/Thx.53.7.601  0.575
1998 Macnee W, Walden IM. Lung research funding in the UK: the British Lung Foundation perspective. Thorax. 53: 239-240. PMID 9741363 DOI: 10.1136/Thx.53.4.239  0.341
1998 Rahman I, Bel A, Mulier B, Donaldson K, MacNee W. Differential regulation of glutathione by oxidants and dexamethasone in alveolar epithelial cells. The American Journal of Physiology. 275: L80-6. PMID 9688938 DOI: 10.1152/Ajplung.1998.275.1.L80  0.531
1998 Morrison D, Skwarski K, Millar A, Adams W, MacNee W. A comparison of three methods of measuring 99mTc-DTPA lung clearance and their repeatability European Respiratory Journal. 11: 1141-1146. PMID 9648969 DOI: 10.1183/09031936.98.11051141  0.347
1998 Rahman I, Smith CA, Antonicelli F, MacNee W. Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1. Febs Letters. 427: 129-33. PMID 9613613 DOI: 10.1016/S0014-5793(98)00410-4  0.478
1998 Mulier B, Rahman I, Watchorn T, Donaldson K, MacNee W, Jeffery PK. Hydrogen peroxide-induced epithelial injury: the protective role of intracellular nonprotein thiols (NPSH). The European Respiratory Journal. 11: 384-91. PMID 9551743 DOI: 10.1183/09031936.98.11020384  0.511
1997 Biernacki W, Redpath AT, Best JJK, Macnee W. Measurement of CT lung density in patients with chronic asthma European Respiratory Journal. 10: 2455-2459. PMID 9426078 DOI: 10.1183/09031936.97.10112455  0.376
1997 Gilmour PS, Brown DM, Beswick PH, MacNee W, Rahman I, Donaldson K. Free radical activity of industrial fibers: role of iron in oxidative stress and activation of transcription factors. Environmental Health Perspectives. 105: 1313-7. PMID 9400744 DOI: 10.1289/Ehp.97105S51313  0.477
1997 Marrades RM, Roca J, Barberà JA, Jover Ld, MacNee W, Rodriguez-Roisin R. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. American Journal of Respiratory and Critical Care Medicine. 156: 425-430. PMID 9279219 DOI: 10.1164/Ajrccm.156.2.9611001  0.333
1997 Rahman I, Skwarska E, MacNee W. Attenuation of oxidant/antioxidant imbalance during treatment of exacerbations of chronic obstructive pulmonary disease. Thorax. 52: 565-8. PMID 9227727 DOI: 10.1136/Thx.52.6.565  0.6
1997 Morrison D, Skwarski KM, MacNee W. The adequacy of oxygenation in patients with hypoxic chronic obstructive pulmonary disease treated with long-term domiciliary oxygen. Respiratory Medicine. 91: 287-291. PMID 9176647 DOI: 10.1016/S0954-6111(97)90032-9  0.332
1997 MacNee W, Skwarski K. The Pathogenesis of Peripheral Edema in Chronic Obstructive Pulmonary Disease Clinical Pulmonary Medicine. 4: 309-315. DOI: 10.1097/00045413-199711000-00001  0.406
1997 MacNee W, Rahman I, Li XY, Morrison D, Donaldsont K. Cigarette smoke-induced oxidant/antioxidant imbalance and its role in increased epithelial permeability Annals of Occupational Hygiene. 41: 728-735. DOI: 10.1093/Annhyg/41.Inhaled_Particles_Viii.728  0.554
1997 Gilmour P, Brown DM, Beswick PH, Benton E, MacNee W, Donaldson K. Surface Free Radical Activity of PM10 and Ultrafine Titanium Dioxide: A Unifying Factor in Their Toxicity? Annals of Occupational Hygiene. 41: 32-38. DOI: 10.1093/Annhyg/41.Inhaled_Particles_Viii.32  0.302
1996 Li XY, Gilmour PS, Donaldson K, MacNee W. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax. 51: 1216-1222. PMID 8994518 DOI: 10.1136/Thx.51.12.1216  0.359
1996 Rahman I, Bel A, Mulier B, Lawson MF, Harrison DJ, Macnee W, Smith CA. Transcriptional regulation of gamma-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells. Biochemical and Biophysical Research Communications. 229: 832-7. PMID 8954980 DOI: 10.1006/Bbrc.1996.1888  0.515
1996 Rahman I, Smith CA, Lawson MF, Harrison DJ, MacNee W. Induction of gamma-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells. Febs Letters. 396: 21-5. PMID 8906859 DOI: 10.1016/0014-5793(96)01027-7  0.538
1996 Rahman I, MacNee W. Role of oxidants/antioxidants in smoking-induced lung diseases. Free Radical Biology & Medicine. 21: 669-81. PMID 8891669 DOI: 10.1016/0891-5849(96)00155-4  0.617
1996 Rahman I, Morrison D, Donaldson K, MacNee W. Systemic oxidative stress in asthma, COPD, and smokers. American Journal of Respiratory and Critical Care Medicine. 154: 1055-60. PMID 8887607 DOI: 10.1164/Ajrccm.154.4.8887607  0.576
1996 Masclans JR, Barberà JA, MacNee W, Pavia J, Piera C, Lomeña F, Chung KF, Roca J, Rodriguez-Roisin R. Salbutamol reduces pulmonary neutrophil sequestration of platelet-activating factor in humans. American Journal of Respiratory and Critical Care Medicine. 154: 529-532. PMID 8756833 DOI: 10.1164/Ajrccm.154.2.8756833  0.351
1996 Rahman I, MacNee W. Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease. Thorax. 51: 348-50. PMID 8733482 DOI: 10.1136/Thx.51.4.348  0.604
1996 Li XY, Rahman I, Donaldson K, MacNee W. Mechanisms of cigarette smoke induced increased airspace permeability. Thorax. 51: 465-71. PMID 8711672 DOI: 10.1136/Thx.51.5.465  0.565
1996 MacNee W, Morrison D, Rahman I, Li XY, Donaldson K. Cigarette smoke and ozone-induced epithelial perturbation in vivo and in vitro. The role of glutathione. Chest. 109: 39S. PMID 8598146 DOI: 10.1378/Chest.109.3_Supplement.39S  0.517
1995 Hogg JC, Coxson HO, Brumwell ML, Beyers N, Doerschuk CM, MacNee W, Wiggs BR. Erythrocyte and polymorphonuclear cell transit time and concentration in human pulmonary capillaries. Journal of Applied Physiology (Bethesda, Md. : 1985). 77: 1795-800. PMID 7836202 DOI: 10.1152/Jappl.1994.77.4.1795  0.302
1995 Seaton A, MacNee W, Donaldson K, Godden D. Particulate air pollution and acute health effects. Lancet. 345: 176-8. PMID 7741860 DOI: 10.1016/S0140-6736(95)90173-6  0.348
1995 Rahman I, Li XY, Donaldson K, Macnee W. Cigarette smoke, glutathione metabolism and epithelial permeability in rat lungs. Biochemical Society Transactions. 23: 235S. PMID 7672256 DOI: 10.1042/Bst023235S  0.536
1995 Brown GM, Brown DM, Donaldson K, Drost E, MacNee W. Neutrophil sequestration in rat lungs. Thorax. 50: 661-667. PMID 7638810 DOI: 10.1136/Thx.50.6.661  0.396
1995 Li XY, Donaldson K, Brown D, MacNee W. The role of tumor necrosis factor in increased airspace epithelial permeability in acute lung inflammation. American Journal of Respiratory Cell and Molecular Biology. 13: 185-195. PMID 7626286 DOI: 10.1165/Ajrcmb.13.2.7626286  0.355
1995 Brown DM, Drost E, Donaldson K, MacNee W. Deformability and CD11/CD18 expression of sequestered neutrophils in normal and inflamed lungs. American Journal of Respiratory Cell and Molecular Biology. 13: 531-539. PMID 7576688 DOI: 10.1165/Ajrcmb.13.5.7576688  0.394
1995 Rahman I, Li XY, Donaldson K, Harrison DJ, MacNee W. Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress. The American Journal of Physiology. 269: L285-92. PMID 7573460 DOI: 10.1152/Ajplung.1995.269.3.L285  0.543
1995 MacNee W, Rahman I. Oxidants/antioxidants in idiopathic pulmonary fibrosis. Thorax. 50: S53-8. PMID 7570466 DOI: 10.1136/Thx.50.Suppl_1.S53  0.556
1995 Morrison D, Skwarski K, MacNee W. Review of the prescription of domiciliary long term oxygen therapy in Scotland. Thorax. 50: 1103-1105. PMID 7491562 DOI: 10.1136/Thx.50.10.1103  0.346
1994 Lannan S, Donaldson K, Brown D, MacNee W. Effect of cigarette smoke and its condensates on alveolar epithelial cell injury in vitro American Journal of Physiology-Lung Cellular and Molecular Physiology. 266. PMID 8304473 DOI: 10.1152/Ajplung.1994.266.1.L92  0.357
1994 MacNee W. Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One. American Journal of Respiratory and Critical Care Medicine. 150: 1158-1168. PMID 8087359 DOI: 10.1164/Ajrccm.150.3.8087359  0.408
1994 Bridgeman MME, Marsden M, Selby C, Morrison D, MacNee W. Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue Thorax. 49: 670-675. PMID 8066561 DOI: 10.1136/Thx.49.7.670  0.362
1994 Böllert FGE, Sime PJ, Macnee W, Crompton GK. Pulmonary Mycobacterium malmoense and aspergillus infection: a fatal combination? Thorax. 49: 521-522. PMID 8016779 DOI: 10.1136/Thx.49.5.521  0.387
1994 Selby C, Drost E, Gillooly M, Cameron E, Lamb D, MacNee W. Neutrophil sequestration in lungs removed at surgery. The effect of microscopic emphysema. American Journal of Respiratory and Critical Care Medicine. 149: 1526-33. PMID 8004309 DOI: 10.1164/Ajrccm.149.6.8004309  0.366
1994 Li XY, Donaldson K, Rahman I, MacNee W. An investigation of the role of glutathione in increased epithelial permeability induced by cigarette smoke in vivo and in vitro. American Journal of Respiratory and Critical Care Medicine. 149: 1518-25. PMID 8004308 DOI: 10.1164/Ajrccm.149.6.8004308  0.554
1994 Buttrum SM, Drost EM, MacNee W, Goffin E, Lockwood CM, Hatton R, Nash GB. Rheological response of neutrophils to different types of stimulation Journal of Applied Physiology. 77: 1801-1810. PMID 7836203 DOI: 10.1152/Jappl.1994.77.4.1801  0.314
1994 Rahman I, Wehbe L, Morrison D, Macnee W. Antioxidant Capacity in Copd, Smokers and Asthmatic Plasma Clinical Science. 87: 17P-17P. DOI: 10.1042/Cs045017P_Pt2  0.533
1994 Rahman I, Lawson M, Harrison D, MacNee W. γ-Glutamylcysteine synthetase induction by cigarette smoke exposure in alveolar epithelial cells Respiratory Medicine. 88: 809-810. DOI: 10.1016/S0954-6111(05)80224-0  0.517
1993 Gould GA, Redpath AT, Ryan M, Warren PM, Best JJK, Cameron EJW, MacNee W. Parenchymal emphysema measured by CT lung density correlates with lung function in patients with bullous disease European Respiratory Journal. 6: 698-704. PMID 8519381 DOI: 10.1016/S0012-3692(16)47462-3  0.37
1993 MacNee W, Selby C. Neutrophil traffic in the lungs: Role of haemodynamics, cell adhesion, and deformability Thorax. 48: 79-88. PMID 8434360 DOI: 10.1136/Thx.48.1.79  0.325
1993 Selby C, Macnee W. Factors affecting neutrophil transit during acute pulmonary inflammation: Minireview Experimental Lung Research. 19: 407-428. PMID 8370343 DOI: 10.3109/01902149309064355  0.398
1993 Skwarski KM, Morrison D, MacNee W. Reversal of hypoxia in a patient with chronic obstructive pulmonary disease, pulmonary hypertension, and oedema during treatment with long term domiciliary oxygen Thorax. 48: 576-577. PMID 8322252 DOI: 10.1136/Thx.48.5.576  0.384
1993 Lamb D, McLean A, Gillooly M, Warren PM, Gould GA, MacNee W. Relation between distal airspace size, bronchiolar attachments, and lung function Thorax. 48: 1012-1017. PMID 8256230 DOI: 10.1136/Thx.48.10.1012  0.378
1993 Drost EM, Selby C, Bridgeman MME, MacNee W. Decreased leukocyte deformability after acute cigarette smoking in humans American Review of Respiratory Disease. 148: 1277-1283. PMID 8239165 DOI: 10.1164/Ajrccm/148.5.1277  0.352
1993 Skwarski K, Lee M, Turnbull L, MacNee W. Atrial natriuretic peptide in stable and decompensated chronic obstructive pulmonary disease. Thorax. 48: 730-735. PMID 8153922 DOI: 10.1136/Thx.48.7.730  0.348
1993 Skwarski KM, Gorecka D, Sliwinski P, Hogg JC, MacNee W. The effects of cigarette smoking on pulmonary hemodynamics Chest. 103: 1166-1172. PMID 8131459 DOI: 10.1378/Chest.103.4.1166  0.396
1992 MacNee W. Predictors of Survival in Patients Treated with Long-Term Oxygen Therapy Respiration. 59: 5-7. PMID 1513973 DOI: 10.1159/000196112  0.302
1992 Selby C, Drost E, Brown D, Howie S, Macnee W. Inhibition of neutrophil adherence and movement by acute cigarette smoke exposure Experimental Lung Research. 18: 813-827. PMID 1468412 DOI: 10.3109/01902149209031709  0.325
1992 Skwarski K, Barratt A, MacNee W. Hemodynamic effects of ibopamine on the pulmonary circulation and right ventricular performance in patients with chronic obstructive pulmonary disease. The Cardiology. 80: 349-355. PMID 1451122 DOI: 10.1159/000175025  0.38
1992 Drost EM, Selby C, Lannan S, Lowe GD, MacNee W. Changes in neutrophil deformability following in vitro smoke exposure: mechanism and protection American Journal of Respiratory Cell and Molecular Biology. 6: 287-295. PMID 1311595 DOI: 10.1165/Ajrcmb/6.3.287  0.332
1992 Drost E, Selby C, Bridgeman M, Dawkes R, Macnee W. Acute Cigarette Smoking Decreases Whole Blood Filterability in vivo without Evidence of Intravascular Oxidant Stress Clinical Science. 83. DOI: 10.1042/Cs083020P  0.306
1991 Selby C, Drost E, Wraith PK, MacNee W. Neutrophil traffic through the lungs in man Annals of the New York Academy of Sciences. 624: 353-354. PMID 2064244 DOI: 10.1111/J.1749-6632.1991.Tb17046.X  0.324
1991 Brown GM, Drost E, Selby C, Donaldson K, MacNee W. Neutrophil sequestration in rat lungs Annals of the New York Academy of Sciences. 624: 316-317. PMID 2064233 DOI: 10.1111/J.1749-6632.1991.Tb17031.X  0.317
1991 Brumwell ML, MacNee W, Doerschuk CM, Wiggs B, Hogg JC. Neutrophil kinetics in normal and emphysematous regions of human lungs. Annals of the New York Academy of Sciences. 624: 30-9. PMID 2064230 DOI: 10.1111/J.1749-6632.1991.Tb17003.X  0.313
1991 Selby C, Drost E, Lannan S, Wraith PK, Macnee W. Neutrophil retention in the lungs of patients with chronic obstructive pulmonary disease American Review of Respiratory Disease. 143: 1359-1364. PMID 2048825 DOI: 10.1164/Ajrccm/143.6.1359  0.437
1991 Brown GM, Drost E, Donaldson K, Macgregor I, Macnee W. Reduction of the proteolytic activity of neutrophils by exposure to cigarette smoke in vitro. Experimental Lung Research. 17: 923-937. PMID 1959503 DOI: 10.3109/01902149109064326  0.317
1991 Skwarski K, MacNee W, Wraith PK, Sliwinski P, Zielinski J. Predictors of survival in patients with chronic obstructive pulmonary disease treated with long-term oxygen therapy Chest. 100: 1522-1527. PMID 1959390 DOI: 10.1378/Chest.100.6.1522  0.312
1991 MacNee W, Bridgeman MM, Marsden M, Drost E, Lannan S, Selby C, Donaldson K. The effects of N-acetylcysteine and glutathione on smoke-induced changes in lung phagocytes and epithelial cells. The American Journal of Medicine. 91: 60S-66S. PMID 1928213 DOI: 10.1016/0002-9343(91)90285-6  0.412
1991 Gugger M, Gould G, Sudlow MF, Wraith PK, MaCnee W. Extent of pulmonary emphysema in man and its relation to the loss of elastic recoil. Clinical Science. 80: 353-358. PMID 1851072 DOI: 10.1042/Cs0800353  0.36
1991 Selby C, Drost E, Wraith PK, MacNee W. In vivo neutrophil sequestration within lungs of humans is determined by in vitro 'filterability' Journal of Applied Physiology. 71: 1996-2003. PMID 1761502 DOI: 10.1152/Jappl.1991.71.5.1996  0.407
1990 Turnbull LW, Ridgway JP, Biernacki W, Mcritchie H, Muir AL, Best JJK, Macnee W. Assessment of the right ventricle by magnetic resonance imaging in chronic obstructive lung disease. Thorax. 45: 597-601. PMID 2402721 DOI: 10.1136/Thx.45.8.597  0.319
1990 MacNee W. Pulmonary neutrophil kinetics. Clinical Physics and Physiological Measurement. 11: 133-139. PMID 2286043 DOI: 10.1088/0143-0815/11/4A/319  0.396
1990 MacNee W, Selby C. Neutrophil kinetics in the lungs Clinical Science. 79: 97-107. PMID 2167809 DOI: 10.1042/Cs0790097  0.333
1990 MacNee W. Should patients have cardiac catheterization prior to long-term oxygen treatment? Lung. 168: 800-808. PMID 2117195 DOI: 10.1007/Bf02718211  0.327
1989 MacNee W, Wiggs B, Belzberg AS, Hogg JC. The effect of cigarette smoking on neutrophil kinetics in human lungs. The New England Journal of Medicine. 321: 924-928. PMID 2779614 DOI: 10.1056/Nejm198910053211402  0.373
1989 MacNee W, Martin BA, Wiggs BR, Belzberg AS, Hogg JC. Regional pulmonary transit times in humans Journal of Applied Physiology. 66: 844-850. PMID 2708213 DOI: 10.1152/Jappl.1989.66.2.844  0.314
1989 Biernacki W, Prince K, Whyte K, MacNee W, Flenley DC. The effect of six months of daily treatment with the beta-2 agonist oral pirbuterol on pulmonary hemodynamics in patients with chronic hypoxic cor pulmonale receiving long-term oxygen therapy American Review of Respiratory Disease. 139: 492-497. PMID 2563321 DOI: 10.1164/Ajrccm/139.2.492  0.319
1989 MacNee W, Lannan S, Lennie S, Drost E, Lowe G. A Mechanism for Neutrophil Sequestration in the Lungs' during Cigarette Smoking Clinical Science. 76. DOI: 10.1042/Cs076021Pc  0.353
1989 Skwarski K, Biernacki W, Sankaran R, Lannan S, Flenley DC, Lee MR, MacNee W. The Effect of Oxygen Therapy on Atrial Natriuretic Peptide (ANP) and Pulmonary Haemodynamics in Patients with Hypoxic Chronic Obstructive Pulmonary Disease (COPD) Clinical Science. 76. DOI: 10.1042/Cs076003Pa  0.386
1988 Gould GA, MacNee W, McLean A, Warren PM, Redpath A, Best JJK, Lamb D, Flenley DC. CT measurements of lung density in life can quantitate distal airspace enlargement - an essential defining feature of human emphysema American Review of Respiratory Disease. 137: 380-392. PMID 3341629 DOI: 10.1164/Ajrccm/137.2.380  0.314
1988 Macnee W, Wathen CG, Flenley DC, Muir AD. The Effects of Controlled Oxygen Therapy on Ventricular function in Patients with Stable and Decompensated Cor Pulmonale The American Review of Respiratory Disease. 137: 1289-1295. PMID 3202369 DOI: 10.1164/Ajrccm/137.6.1289  0.333
1988 Biernacki W, Flenley DC, Muir AL, MacNee W. Pulmonary hypertension and right ventricular function in patients with COPD. Chest. 94: 1169-1175. PMID 3191757 DOI: 10.1378/Chest.94.6.1169  0.328
1988 Prescott RJ, Biernacki W, Muir AL, Macnee W. Does right ventricular function predict survival in patients with chronic obstructive lung disease Thorax. 43: 621-626. PMID 3175974 DOI: 10.1136/Thx.43.8.621  0.376
1988 MacNee W. Right ventricular function in cor pulmonale. The Cardiology. 75: 30-40. PMID 3069214 DOI: 10.1159/000174443  0.368
1988 Turnbull L, Ridgway J, Biernacki W, MacRitchie H, Muir A, Best J, MacNee W. Measurement of Right Ventricular Dimensions in Chronic Obstructive Pulmonary Disease (COPD) Using Magnetic Resonance Imaging (MRI) Clinical Science. 75. DOI: 10.1042/Cs075006P  0.338
1988 Biernacki W, Flenley DC, Muir AL, Macnee W. Does the Presence of Pulmonary Hypertension Depress Right Ventricular Performance in Patients with Stable Chronic Obstructive Pulmonary Disease (COPD) Clinical Science. 74. DOI: 10.1042/Cs074039P  0.385
1988 Macnee W, Lannan S, Biernacki W, Wraith P. The Determinants of Pulmonary Transit Time in Chronic Obstructive Pulmonary Disease (COPD) Clinical Science. 74. DOI: 10.1042/Cs074028P  0.403
1986 MacNee W, Connaughton JJ, Rhind GB, Hayhurst MD, Douglas NJ, Muir AL, Flenley DC. A comparison of the effects of almitrine or oxygen breathing on pulmonary arterial pressure and right ventricular ejection fraction in hypoxic chronic bronchitis and emphysema. The American Review of Respiratory Disease. 134: 559-65. PMID 3752712 DOI: 10.1164/Arrd.1986.134.3.559  0.316
1986 Flenley DC, MacNee W, Gould G, Redpath A, Best JJK, McLean A, Lamb D. Quantitative Computerised Tomography Scan Can Diagnose, Quantitate and Locate Pulmonary Emphysema Non-Invasively in Humans Respiration. 50: 3-4. DOI: 10.1159/000195081  0.325
1985 MacNee W, Morgan AD, Wathen CG, Muir AL, Flenley DC. Right ventricular performance during exercise in chronic obstructive pulmonary disease. The effects of oxygen. Respiration; International Review of Thoracic Diseases. 48: 206-15. PMID 4070799 DOI: 10.1159/000194831  0.319
1985 MacNee W, Buist TA, Finlayson ND, Lamb D, Miller HC, Muir AL, Douglas AC. Multiple microscopic pulmonary arteriovenous connections in the lungs presenting as cyanosis. Thorax. 40: 316-8. PMID 4023984 DOI: 10.1136/Thx.40.4.316  0.371
1984 Hayhurst MD, MacNee W, Flenley DC, Wright D, McLean A, Lamb D, Wightman AJ, Best J. Diagnosis of pulmonary emphysema by computerised tomography. Lancet (London, England). 2: 320-2. PMID 6146866 DOI: 10.1016/S0140-6736(84)92689-8  0.338
1983 MacNee W, Power J, Innes A, Douglas NJ, Sudlow MF. The Dependence of Maximal Flow in Man on the Airway Gas Physical Properties Clinical Science. 65: 273-279. PMID 6872461 DOI: 10.1042/Cs0650273  0.334
1983 MacNee W, Xue QF, Hannan WJ, Flenley DC, Adie CJ, Muir AL. Assessment by radionuclide angiography of right and left ventricular function in chronic bronchitis and emphysema. Thorax. 38: 494-500. PMID 6612636 DOI: 10.1136/Thx.38.7.494  0.339
1983 MacNee W, Wathen CG, Hannan WJ, Flenley DC, Muir AL. Effects of pirbuterol and sodium nitroprusside on pulmonary haemodynamics in hypoxic cor pulmonale. British Medical Journal (Clinical Research Ed.). 287: 1169-72. PMID 6138118 DOI: 10.1136/Bmj.287.6400.1169  0.353
1983 MacNee W, Morgan A, Wathen C, Hannan W, Flenley D, Muir A. The Acute Effects of Oxygen on Right Ventricular Performance in Patients with Chronic Hypoxic Bronchitis and Emphysema Clinical Science. 64. DOI: 10.1042/Cs064033P  0.312
1982 Macnee W, Wathen GG, Xue QF, Hannan WJ, Flenley DC, Muir AL. The Effects of Pirbuterol on the Pulmonary Circulation and Right Ventricular Performance in Chronic Hypoxic, Bronchitis and Emphysema Clinical Science. 63. DOI: 10.1042/Cs063051P  0.367
1982 MacNee W, Douglas C, Nj D, Sudlow M. Effects of Breathing Gases of Different Physical Properties in Patients with Chronic Airflow Obstruction Clinical Science. 62. DOI: 10.1042/Cs062054Pa  0.324
Show low-probability matches.