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Xiao-chen Bai - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liu S, Chen H, Yin Y, Lu D, Gao G, Li J, Bai XC, Zhang X. Inhibition of FAM46/TENT5 activity by BCCIPα adopting a unique fold. Science Advances. 9: eadf5583. PMID 37018411 DOI: 10.1126/sciadv.adf5583  0.302
2022 Cai K, Zhang X, Bai XC. Cryo-electron Microscopic Analysis of Single-Pass Transmembrane Receptors. Chemical Reviews. PMID 35715229 DOI: 10.1021/acs.chemrev.1c01035  0.338
2020 Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y. Structural insights into the Ca-dependent gating of the human mitochondrial calcium uniporter. Elife. 9. PMID 32762847 DOI: 10.7554/Elife.60513  0.329
2020 Xue J, Xie T, Zeng W, Jiang Y, Bai XC. Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations. Elife. 9. PMID 32723473 DOI: 10.7554/Elife.58823  0.425
2020 Zhang X, Bai XC, Chen ZJ. Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway. Immunity. 53: 43-53. PMID 32668227 DOI: 10.1016/J.Immuni.2020.05.013  0.3
2020 Shi Z, Gao H, Bai XC, Yu H. Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science (New York, N.Y.). PMID 32409525 DOI: 10.1126/Science.Abb0981  0.339
2020 Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai X, Jiang Y. Author response: Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter Elife. DOI: 10.7554/Elife.60513.Sa2  0.315
2020 Xue J, Xie T, Zeng W, Jiang Y, Bai X. Author response: Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations Elife. DOI: 10.7554/Elife.58823.Sa2  0.339
2019 Li J, Shang G, Chen YJ, Brautigam CA, Liou J, Zhang X, Bai XC. Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. Elife. 8. PMID 31535977 DOI: 10.7554/Elife.47650  0.36
2019 Uchikawa E, Choi E, Shang G, Yu H, Bai XC. Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife. 8. PMID 31436533 DOI: 10.7554/Elife.48630  0.315
2019 Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y. Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell. PMID 31080062 DOI: 10.1016/J.Cell.2019.03.050  0.398
2019 Chen Q, Zeng W, She J, Bai X, Jiang Y. Structural and functional characterization of an otopetrin family proton channel. Elife. 8. PMID 30973323 DOI: 10.7554/Elife.46710  0.366
2019 She J, Zeng W, Guo J, Chen Q, Bai X, Jiang Y. Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife. 8. PMID 30860481 DOI: 10.2210/Pdb6Nq2/Pdb  0.401
2019 Shang G, Zhang C, Chen ZJ, Bai XC, Zhang X. Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature. PMID 30842659 DOI: 10.2210/Pdb6Nt5/Pdb  0.409
2019 Uchikawa E, Choi E, Shang G, Yu H, Bai X. Author response: Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor–ligand complex Elife. DOI: 10.7554/Elife.48630.030  0.335
2019 Chen Q, Zeng W, She J, Bai X, Jiang Y. Author response: Structural and functional characterization of an otopetrin family proton channel Elife. DOI: 10.7554/Elife.46710.024  0.301
2019 She J, Zeng W, Guo J, Chen Q, Bai X, Jiang Y. Author response: Structural mechanisms of phospholipid activation of the human TPC2 channel Elife. DOI: 10.7554/Elife.45222.030  0.333
2018 Nguyen NX, Armache JP, Lee C, Yang Y, Zeng W, Mootha VK, Cheng Y, Bai XC, Jiang Y. Author Correction: Cryo-EM structure of a fungal mitochondrial calcium uniporter. Nature. PMID 30108362 DOI: 10.1038/S41586-018-0427-1  0.32
2018 Nguyen NX, Armache JP, Lee C, Yang Y, Zeng W, Mootha VK, Cheng Y, Bai XC, Jiang Y. Cryo-EM structure of a fungal mitochondrial calcium uniporter. Nature. PMID 29995855 DOI: 10.1038/S41586-018-0333-6  0.303
2018 García-Nafría J, Lee Y, Bai X, Carpenter B, Tate CG. Cryo-EM structure of the adenosine A receptor coupled to an engineered heterotrimeric G protein. Elife. 7. PMID 29726815 DOI: 10.7554/Elife.35946  0.333
2017 Brown A, Rathore S, Kimanius D, Aibara S, Bai XC, Rorbach J, Amunts A, Ramakrishnan V. Structures of the human mitochondrial ribosome in native states of assembly. Nature Structural & Molecular Biology. PMID 28892042 DOI: 10.1038/Nsmb.3464  0.35
2017 Fitzpatrick AWP, Llabrés S, Neuberger A, Blaza JN, Bai XC, Okada U, Murakami S, van Veen HW, Zachariae U, Scheres SHW, Luisi BF, Du D. Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump. Nature Microbiology. 2: 17070. PMID 28504659 DOI: 10.1038/Nmicrobiol.2017.70  0.63
2017 Wong W, Bai XC, Sleebs BE, Triglia T, Brown A, Thompson JK, Jackson KE, Hanssen E, Marapana DS, Fernandez IS, Ralph SA, Cowman AF, Scheres SH, Baum J. Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nature Microbiology. 2: 17031. PMID 28288098 DOI: 10.1038/nmicrobiol.2017.31  0.552
2017 Boland A, Martin TG, Zhang Z, Yang J, Bai XC, Chang L, Scheres SH, Barford D. Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution. Nature Structural & Molecular Biology. PMID 28263324 DOI: 10.1038/Nsmb.3386  0.629
2017 Li Y, Zhou M, Hu Q, Bai XC, Huang W, Scheres SH, Shi Y. Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme. Proceedings of the National Academy of Sciences of the United States of America. PMID 28143931 DOI: 10.1073/Pnas.1620626114  0.586
2017 Fica SM, Oubridge C, Galej WP, Wilkinson ME, Bai XC, Newman AJ, Nagai K. Structure of a spliceosome remodelled for exon ligation. Nature. PMID 28076345 DOI: 10.1038/nature21078  0.335
2016 Martin TG, Bharat TA, Joerger AC, Bai XC, Praetorius F, Fersht AR, Dietz H, Scheres SH. Design of a molecular support for cryo-EM structure determination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821763 DOI: 10.1073/Pnas.1612720113  0.602
2016 Nguyen TH, Galej WP, Bai XC, Oubridge C, Newman AJ, Scheres SH, Nagai K. Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution. Nature. PMID 26829225 DOI: 10.1038/nature16940  0.594
2016 Bai X, Rajendra E, Yang G, Shi Y, Scheres S. EC-01-02: Structure of Γ-Secretases and Implications for Drug Development Alzheimer's & Dementia. 12: P161-P161. DOI: 10.1016/J.Jalz.2016.06.288  0.584
2015 Bai XC, Rajendra E, Yang G, Shi Y, Scheres SH. Sampling the conformational space of the catalytic subunit of human γ-secretase. Elife. 4. PMID 26623517 DOI: 10.7554/Elife.11182  0.638
2015 Zhou M, Li Y, Hu Q, Bai XC, Huang W, Yan C, Scheres SH, Shi Y. Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1. Genes & Development. PMID 26543158 DOI: 10.1101/Gad.272278.115  0.628
2015 Bai XC, Yan C, Yang G, Lu P, Ma D, Sun L, Zhou R, Scheres SH, Shi Y. An atomic structure of human γ-secretase. Nature. 525: 212-7. PMID 26280335 DOI: 10.1038/Nature14892  0.614
2015 Nguyen TH, Galej WP, Bai XC, Savva CG, Newman AJ, Scheres SH, Nagai K. The architecture of the spliceosomal U4/U6.U5 tri-snRNP. Nature. 523: 47-52. PMID 26106855 DOI: 10.1038/nature14548  0.559
2015 Pang Y, Bai XC, Yan C, Hao Q, Chen Z, Wang JW, Scheres SH, Shi Y. Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila. Genes & Development. 29: 277-87. PMID 25644603 DOI: 10.1101/Gad.255877.114  0.629
2015 Bai XC, McMullan G, Scheres SH. How cryo-EM is revolutionizing structural biology. Trends in Biochemical Sciences. 40: 49-57. PMID 25544475 DOI: 10.1016/j.tibs.2014.10.005  0.605
2014 Brown A, Amunts A, Bai XC, Sugimoto Y, Edwards PC, Murshudov G, Scheres SH, Ramakrishnan V. Structure of the large ribosomal subunit from human mitochondria. Science (New York, N.Y.). 346: 718-22. PMID 25278503 DOI: 10.1126/Science.1258026  0.611
2014 Lu P, Bai XC, Ma D, Xie T, Yan C, Sun L, Yang G, Zhao Y, Zhou R, Scheres SH, Shi Y. Three-dimensional structure of human γ-secretase. Nature. 512: 166-70. PMID 25043039 DOI: 10.1038/Nature13567  0.618
2014 Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH. Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife. 3. PMID 24913268 DOI: 10.7554/eLife.03080  0.56
2014 Fernández IS, Bai XC, Murshudov G, Scheres SH, Ramakrishnan V. Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome. Cell. 157: 823-31. PMID 24792965 DOI: 10.1016/J.Cell.2014.04.015  0.603
2014 Amunts A, Brown A, Bai XC, Llácer JL, Hussain T, Emsley P, Long F, Murshudov G, Scheres SH, Ramakrishnan V. Structure of the yeast mitochondrial large ribosomal subunit. Science (New York, N.Y.). 343: 1485-9. PMID 24675956 DOI: 10.1126/Science.1249410  0.659
2014 Wong W, Bai X, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH. Author response: Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine Elife. DOI: 10.7554/Elife.03080.019  0.353
2014 Brown A, Amunts A, Bai X, Llácer J, Hussain T, Emsley P, Long F, Murshudov G, Scheres S, Ramakrishnan V. The Structure of the Yeast Mitochondrial Large Ribosomal Subunit Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314089487  0.611
2013 Fernández IS, Bai XC, Hussain T, Kelley AC, Lorsch JR, Ramakrishnan V, Scheres SH. Molecular architecture of a eukaryotic translational initiation complex. Science (New York, N.Y.). 342: 1240585. PMID 24200810 DOI: 10.1126/science.1240585  0.611
2013 Bai XC, Fernandez IS, McMullan G, Scheres SH. Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles. Elife. 2: e00461. PMID 23427024 DOI: 10.7554/eLife.00461  0.557
2013 Bai X, Fernandez IS, McMullan G, Scheres SH. Author response: Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles Elife. DOI: 10.7554/Elife.00461.011  0.372
2012 Bai XC, Martin TG, Scheres SH, Dietz H. Cryo-EM structure of a 3D DNA-origami object. Proceedings of the National Academy of Sciences of the United States of America. 109: 20012-7. PMID 23169645 DOI: 10.1073/Pnas.1215713109  0.548
2012 Chang LF, Chen S, Liu CC, Pan X, Jiang J, Bai XC, Xie X, Wang HW, Sui SF. Structural characterization of full-length NSF and 20S particles. Nature Structural & Molecular Biology. 19: 268-75. PMID 22307055 DOI: 10.1038/nsmb.2237  0.3
2007 Liu J, Guo T, Wu J, Bai X, Zhou Q, Sui SF. Overexpression of complexin in PC12 cells inhibits exocytosis by preventing SNARE complex recycling. Biochemistry. Biokhimii︠a︡. 72: 439-44. PMID 17511609 DOI: 10.1134/S0006297907040116  0.306
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