Year |
Citation |
Score |
2024 |
Zilberg G, Parpounas AK, Warren AL, Yang S, Wacker D. Molecular basis of human trace amine-associated receptor 1 activation. Nature Communications. 15: 108. PMID 38168118 DOI: 10.1038/s41467-023-44601-4 |
0.513 |
|
2023 |
Zilberg G, Parpounas AK, Warren AL, Yang S, Wacker D. Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation. Biorxiv : the Preprint Server For Biology. PMID 37986760 DOI: 10.1101/2023.09.06.556555 |
0.513 |
|
2023 |
Sanchez-Reyes OB, Zilberg G, McCorvy JD, Wacker D. Molecular Insights into GPCR Mechanisms for Drugs of Abuse. The Journal of Biological Chemistry. 105176. PMID 37599003 DOI: 10.1016/j.jbc.2023.105176 |
0.316 |
|
2020 |
Kim K, Che T, Panova O, DiBerto JF, Lyu J, Krumm BE, Wacker D, Robertson MJ, Seven AB, Nichols DE, Shoichet BK, Skiniotis G, Roth BL. Structure of a Hallucinogen-Activated Gq-Coupled 5-HT Serotonin Receptor. Cell. 182: 1574-1588.e19. PMID 32946782 DOI: 10.1016/J.Cell.2020.08.024 |
0.524 |
|
2020 |
Zilberg G, Wacker D. A Novel Cryo-EM Structure Enables Development of Selective Cannabinoid Receptor Drugs. Biochemistry. PMID 32324378 DOI: 10.1021/acs.biochem.0c00263 |
0.448 |
|
2020 |
Che T, English J, Krumm BE, Kim K, Pardon E, Olsen RHJ, Wang S, Zhang S, Diberto JF, Sciaky N, Carroll FI, Steyaert J, Wacker D, Roth BL. Nanobody-enabled monitoring of kappa opioid receptor states. Nature Communications. 11: 1145. PMID 32123179 DOI: 10.1038/S41467-020-14889-7 |
0.472 |
|
2018 |
McCorvy JD, Wacker D, Wang S, Agegnehu B, Liu J, Lansu K, Tribo AR, Olsen RHJ, Che T, Jin J, Roth BL. Structural determinants of 5-HT receptor activation and biased agonism. Nature Structural & Molecular Biology. PMID 30127358 DOI: 10.1038/S41594-018-0116-7 |
0.522 |
|
2018 |
Capper MJ, Wacker D. How the ubiquitous GPCR receptor family selectively activates signalling pathways. Nature. 558: 529-530. PMID 29946098 DOI: 10.1038/D41586-018-05503-4 |
0.504 |
|
2018 |
Wang S, Che T, Levit A, Shoichet BK, Wacker D, Roth BL. Structure of the Ddopamine receptor bound to the atypical antipsychotic drug risperidone. Nature. PMID 29466326 DOI: 10.1038/Nature25758 |
0.468 |
|
2018 |
Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, ... Wacker D, et al. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell. PMID 29398112 DOI: 10.1016/J.Cell.2018.01.001 |
0.801 |
|
2018 |
Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, ... ... Wacker D, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011 |
0.753 |
|
2017 |
Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science (New York, N.Y.). 358: 381-386. PMID 29051383 DOI: 10.1126/Science.Aan5468 |
0.571 |
|
2017 |
Wacker D, Stevens RC, Roth BL. How Ligands Illuminate GPCR Molecular Pharmacology. Cell. 170: 414-427. PMID 28753422 DOI: 10.1016/J.Cell.2017.07.009 |
0.671 |
|
2017 |
Ishchenko A, Wacker D, Kapoor M, Zhang A, Han GW, Basu S, Patel N, Messerschmidt M, Weierstall U, Liu W, Katritch V, Roth BL, Stevens RC, Cherezov V. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716900 DOI: 10.1073/Pnas.1700891114 |
0.757 |
|
2017 |
Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell. 168: 377-389.e12. PMID 28129538 DOI: 10.1016/J.Cell.2016.12.033 |
0.593 |
|
2016 |
Wacker D, Roth BL. An alerting structure: human orexin receptor 1. Nature Structural & Molecular Biology. 23: 265-6. PMID 27045444 DOI: 10.1038/Nsmb.3198 |
0.611 |
|
2014 |
Liu W, Wacker D, Wang C, Abola E, Cherezov V. Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130314. PMID 24914147 DOI: 10.1098/Rstb.2013.0314 |
0.598 |
|
2014 |
Weierstall U, James D, Wang C, White TA, Wang D, Liu W, Spence JC, Bruce Doak R, Nelson G, Fromme P, Fromme R, Grotjohann I, Kupitz C, Zatsepin NA, Liu H, ... ... Wacker D, et al. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature Communications. 5: 3309. PMID 24525480 DOI: 10.1038/Ncomms4309 |
0.728 |
|
2013 |
Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, et al. Serial femtosecond crystallography of G protein-coupled receptors. Science (New York, N.Y.). 342: 1521-4. PMID 24357322 DOI: 10.1126/Science.1244142 |
0.763 |
|
2013 |
Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, et al. Structure of the human glucagon class B G-protein-coupled receptor. Nature. 499: 444-9. PMID 23863937 DOI: 10.1038/Nature12393 |
0.759 |
|
2013 |
Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC. Structural features for functional selectivity at serotonin receptors. Science (New York, N.Y.). 340: 615-9. PMID 23519215 DOI: 10.1126/Science.1232808 |
0.76 |
|
2013 |
Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, et al. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). 340: 610-4. PMID 23519210 DOI: 10.1126/Science.1232807 |
0.805 |
|
2012 |
Ferrero DM, Wacker D, Roque MA, Baldwin MW, Stevens RC, Liberles SD. Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. Acs Chemical Biology. 7: 1184-9. PMID 22545963 DOI: 10.1021/Cb300111E |
0.689 |
|
2012 |
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, et al. Structure of the human κ-opioid receptor in complex with JDTic. Nature. 485: 327-32. PMID 22437504 DOI: 10.1038/Nature10939 |
0.75 |
|
2011 |
Thompson AA, Liu JJ, Chun E, Wacker D, Wu H, Cherezov V, Stevens RC. GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Methods (San Diego, Calif.). 55: 310-7. PMID 22041719 DOI: 10.1016/J.Ymeth.2011.10.011 |
0.733 |
|
2010 |
Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC. Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. Journal of the American Chemical Society. 132: 11443-5. PMID 20669948 DOI: 10.1021/Ja105108Q |
0.751 |
|
2009 |
Seo HS, Ma Y, Debler EW, Wacker D, Kutik S, Blobel G, Hoelz A. Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 14281-6. PMID 19706512 DOI: 10.1073/Pnas.0907453106 |
0.361 |
|
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