Malu G Tansey - Publications

Affiliations: 
Physiology Emory University, Atlanta, GA 

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Boles JS, Holt J, Cole CL, Neighbarger NK, Urs NM, Huarte OU, Tansey MG. Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis. Biorxiv : the Preprint Server For Biology. PMID 38405709 DOI: 10.1101/2024.02.12.580010  0.334
2024 Imomnazarov K, Lopez-Scarim J, Bagheri I, Joers V, Tansey MG, Martín-Peña A. Biochemical fractionation of human α-Synuclein in a model of synucleinopathies. Biorxiv : the Preprint Server For Biology. PMID 38370694 DOI: 10.1101/2024.02.05.579034  0.71
2023 Martín-Peña A, Tansey MG. Calcium influx into astrocytes plays a pivotal role in inflammation-driven behaviors. Cell Calcium. 117: 102838. PMID 38070458 DOI: 10.1016/j.ceca.2023.102838  0.771
2023 Gillett DA, Wallings RL, Uriarte Huarte O, Tansey MG. Progranulin and GPNMB: interactions in endo-lysosome function and inflammation in neurodegenerative disease. Journal of Neuroinflammation. 20: 286. PMID 38037070 DOI: 10.1186/s12974-023-02965-w  0.807
2023 Wallings RL, Mark JR, Staley HA, Gillett DA, Neighbarger N, Kordasiewicz H, Hirst WD, Tansey MG. ASO-mediated knockdown or kinase inhibition of -Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages. Molecular Therapy. Nucleic Acids. 34: 102064. PMID 38028198 DOI: 10.1016/j.omtn.2023.102064  0.81
2023 Harms AS, Yang YT, Tansey MG. Central and peripheral innate and adaptive immunity in Parkinson's disease. Science Translational Medicine. 15: eadk3225. PMID 37939158 DOI: 10.1126/scitranslmed.adk3225  0.699
2023 Wallings RL, McFarland K, Staley HA, Neighbarger N, Schaake S, Brüggemann N, Zittel S, Usnich T, Klein C, Sammler EM, Tansey MG. The mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner. Biorxiv : the Preprint Server For Biology. PMID 37905053 DOI: 10.1101/2023.10.12.562063  0.802
2023 Wallings RL, Mark JR, Staley HA, Gillett DA, Neighbarger N, Kordasiewicz H, Hirst WD, Tansey MG. Totally tubular: ASO-mediated knock-down of -Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages. Biorxiv : the Preprint Server For Biology. PMID 37503274 DOI: 10.1101/2023.07.14.549028  0.81
2023 Anderson A, Tansey MG. Loss of Progranulin Results in Increased Pan-Cathepsin Activity and Reduced LAMP1 Lysosomal Protein. Biorxiv : the Preprint Server For Biology. PMID 37503267 DOI: 10.1101/2023.07.15.549151  0.349
2023 Tansey MG, Harms AS. Editorial: Glial-targeted therapeutics for CNS disease: getting there from here. Frontiers in Cellular Neuroscience. 17: 1231648. PMID 37465212 DOI: 10.3389/fncel.2023.1231648  0.604
2023 MacPherson KP, Eidson LN, Houser MC, Weiss BE, Gollihue JL, Herrick MK, de Sousa Rodrigues ME, Sniffen L, Weekman EM, Hamilton AM, Kelly SD, Oliver DL, Yang Y, Chang J, Sampson TR, ... ... Tansey MG, et al. Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer's disease mouse model. Frontiers in Cellular Neuroscience. 17: 895017. PMID 37006470 DOI: 10.3389/fncel.2023.895017  0.823
2023 Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, ... ... Tansey MG, et al. APOE and immunity: Research highlights. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36975090 DOI: 10.1002/alz.13020  0.81
2023 Martín-Peña A, Tansey MG. The Alzheimer's risk gene APOE modulates the gut-brain axis. Nature. PMID 36747101 DOI: 10.1038/d41586-023-00261-4  0.786
2022 Houser MC, Uriarte Huarte O, Wallings RL, Keating CE, MacPherson KP, Herrick MK, Kannarkat GT, Kelly SD, Chang J, Varvel NH, Rexach JE, Tansey MG. Progranulin loss results in sex-dependent dysregulation of the peripheral and central immune system. Frontiers in Immunology. 13: 1056417. PMID 36618392 DOI: 10.3389/fimmu.2022.1056417  0.791
2022 Vecchiarelli HA, Joers V, Tansey MG, Starowicz K. Editorial: Cannabinoids in neuroinflammation, neurodegeneration and pain: Focus on non-neuronal cells. Frontiers in Neuroscience. 16: 1114775. PMID 36605549 DOI: 10.3389/fnins.2022.1114775  0.691
2022 Houser MC, Smith DJ, Rhodes D, Glick-Smith JL, Chovan P, Ferranti E, Dunbar SB, Tansey MG, Hertzberg V, Mac VV. Inflammatory profiles, gut microbiome, and kidney function are impacted after high-fidelity firefighter training. International Journal of Hygiene and Environmental Health. 248: 114107. PMID 36577282 DOI: 10.1016/j.ijheh.2022.114107  0.696
2022 Gopinath A, Mackie PM, Phan LT, Tansey MG, Khoshbouei H. The complex role of inflammation and gliotransmitters in Parkinson's disease. Neurobiology of Disease. 105940. PMID 36470499 DOI: 10.1016/j.nbd.2022.105940  0.41
2022 Menees KB, Otero BA, Tansey MG. Microbiome influences on neuro-immune interactions in neurodegenerative disease. International Review of Neurobiology. 167: 25-57. PMID 36427957 DOI: 10.1016/bs.irn.2022.07.006  0.819
2022 Wallings RL, Hughes LP, Staley HA, Simon ZD, McFarland NR, Alcalay RN, Garrido A, Martí MJ, Sarró ET, Dzamko N, Tansey MG. WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and Glucocerebrosidase Enzymatic Activity in Parkinson's Disease Monocytes. Frontiers in Cellular Neuroscience. 16: 892899. PMID 35755775 DOI: 10.3389/fncel.2022.892899  0.805
2022 Xie A, Ensink E, Li P, Gordevičius J, Marshall LL, George S, Pospisilik JA, Aho VTE, Houser MC, Pereira PAB, Rudi K, Paulin L, Tansey MG, Auvinen P, Brundin P, et al. Bacterial Butyrate in Parkinson's Disease Is Linked to Epigenetic Changes and Depressive Symptoms. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35723531 DOI: 10.1002/mds.29128  0.766
2022 Tansey MG, Wallings RL, Houser MC, Herrick MK, Keating CE, Joers V. Inflammation and immune dysfunction in Parkinson disease. Nature Reviews. Immunology. PMID 35246670 DOI: 10.1038/s41577-022-00684-6  0.83
2021 Houser MC, Caudle WM, Chang J, Kannarkat GT, Yang Y, Kelly SD, Oliver D, Joers V, Shannon KM, Keshavarzian A, Tansey MG. Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. Acta Neuropathologica Communications. 9: 139. PMID 34412704 DOI: 10.1186/s40478-021-01240-4  0.838
2021 Gopinath A, Badov M, Francis M, Shaw G, Collins A, Miller DR, Hansen CA, Mackie P, Tansey MG, Dagra A, Madorsky I, Ramirez-Zamora A, Okun MS, Streit WJ, Khoshbouei H. TNFα increases tyrosine hydroxylase expression in human monocytes. Npj Parkinson's Disease. 7: 62. PMID 34285243 DOI: 10.1038/s41531-021-00201-x  0.336
2021 Houser MC, Mac V, Smith DJ, Chicas RC, Xiuhtecutli N, Flocks JD, Elon L, Tansey MG, Sands JM, McCauley L, Hertzberg VS. Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers. Biological Research For Nursing. 10998004211016070. PMID 34018403 DOI: 10.1177/10998004211016070  0.701
2021 Herrick MK, Tansey MG. Is LRRK2 the missing link between inflammatory bowel disease and Parkinson's disease? Npj Parkinson's Disease. 7: 26. PMID 33750819 DOI: 10.1038/s41531-021-00170-1  0.824
2021 Aho VTE, Houser MC, Pereira PAB, Chang J, Rudi K, Paulin L, Hertzberg V, Auvinen P, Tansey MG, Scheperjans F. Relationships of gut microbiota, short-chain fatty acids, inflammation, and the gut barrier in Parkinson's disease. Molecular Neurodegeneration. 16: 6. PMID 33557896 DOI: 10.1186/s13024-021-00427-6  0.773
2020 Kline EM, Houser MC, Herrick MK, Seibler P, Klein C, West A, Tansey MG. Genetic and Environmental Factors in Parkinson's Disease Converge on Immune Function and Inflammation. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33314312 DOI: 10.1002/mds.28411  0.825
2020 Hollville E, Joers V, Nakamura A, Swahari V, Tansey MG, Moy SS, Deshmukh M. Characterization of a Cul9-Parkin double knockout mouse model for Parkinson's disease. Scientific Reports. 10: 16886. PMID 33037272 DOI: 10.1038/s41598-020-73854-y  0.784
2020 Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, ... ... Tansey MG, et al. Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32868457 DOI: 10.1523/Jneurosci.1468-19.2020  0.827
2020 Joers V, Masilamoni G, Kempf D, Weiss AR, Rotterman TM, Murray B, Yalcin-Cakmakli G, Voll RJ, Goodman MM, Howell L, Bachevalier J, Green S, Naqib A, Shaikh M, Engen P, ... ... Tansey MG, et al. Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series. Neurobiology of Disease. 105027. PMID 32712266 DOI: 10.1016/J.Nbd.2020.105027  0.83
2020 Wallings RL, Herrick MK, Tansey MG. LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson's. Frontiers in Neuroscience. 14: 443. PMID 32508566 DOI: 10.3389/Fnins.2020.00443  0.835
2020 Cable J, Holtzman DM, Hyman BT, Tansey MG, Colonna M, Kellis M, Brinton RD, Albert M, Wellington CL, Sisodia SS, Tanzi RE. Alternatives to amyloid for Alzheimer's disease therapies-a symposium report. Annals of the New York Academy of Sciences. PMID 32472577 DOI: 10.1111/Nyas.14371  0.367
2020 Wallings RL, Herrick MK, Tansey MG. Linking mitochondria to the immune response. Elife. 9. PMID 32293561 DOI: 10.7554/Elife.56214  0.807
2020 Sarkar S, Dammer EB, Malovic E, Olsen AL, Raza SA, Gao T, Xiao H, Oliver DL, Duong D, Joers V, Seyfried N, Huang M, Kukar T, Tansey MG, Kanthasamy AG, et al. Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Frontiers in Immunology. 11: 33. PMID 32082315 DOI: 10.1096/Fasebj.2020.34.S1.00630  0.785
2020 Sanyal A, DeAndrade MP, Novis HS, Lin S, Chang J, Lengacher N, Tomlinson JJ, Tansey MG, LaVoie MJ. Lysosome and Inflammatory Defects in GBA1-Mutant Astrocytes Are Normalized by LRRK2 Inhibition. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32034799 DOI: 10.1002/Mds.27994  0.401
2020 Kelly R, Joers V, Tansey MG, McKernan DP, Dowd E. Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson's Disease. Molecules (Basel, Switzerland). 25. PMID 31973235 DOI: 10.3390/Molecules25030453  0.788
2019 De Sousa Rodrigues ME, Houser MC, Walker DI, Jones DP, Chang J, Barnum CJ, Tansey MG. Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer's disease associated with obesity, metabolic syndrome, and type 2 diabetes. Alzheimer's Research & Therapy. 12: 1. PMID 31892368 DOI: 10.1186/S13195-019-0546-4  0.797
2019 Tansey MG. Editorial for Special issue on Microbiome in neurological and psychiatric disease. Neurobiology of Disease. 135: 104699. PMID 31786369 DOI: 10.1016/J.Nbd.2019.104699  0.335
2019 Wallings RL, Tansey MG. LRRK2 regulation of immune-pathways and inflammatory disease. Biochemical Society Transactions. PMID 31769472 DOI: 10.1042/Bst20180463  0.819
2019 Herrick MK, Tansey MG. Infection triggers symptoms similar to those of Parkinson's disease in mice lacking PINK1 protein. Nature. 571: 481-482. PMID 31337898 DOI: 10.1038/D41586-019-02094-6  0.798
2019 Eidson LN, Rodrigues MED, Johnson MA, Barnum CJ, Duke BJ, Yang Y, Chang J, Kelly SD, Wildner M, Tesi RJ, Tansey MG. Chronic psychological stress during adolescence induces sex-dependent adulthood inflammation, increased adiposity, and abnormal behaviors that are ameliorated by selective inhibition of soluble Tumor Necrosis Factor with XPro1595. Brain, Behavior, and Immunity. PMID 31251975 DOI: 10.1016/J.Bbi.2019.06.027  0.735
2019 Kline EM, Butkovich LM, Bradner JM, Chang J, Gelbard H, Goodfellow V, Caudle WM, Tansey MG. The second generation mixed-lineage kinase-3 (MLK3) inhibitor CLFB-1134 protects against neurotoxin-induced nigral dopaminergic neuron loss. Experimental Neurology. PMID 31077715 DOI: 10.1016/J.Expneurol.2019.05.002  0.802
2019 Chandrasekharan B, Saeedi BJ, Alam A, Houser M, Srinivasan S, Tansey M, Jones R, Nusrat A, Neish AS. Interactions Between Commensal Bacteria and Enteric Neurons, via FPR1 Induction of ROS, Increase Gastrointestinal Motility in Mice. Gastroenterology. PMID 30930024 DOI: 10.1053/J.Gastro.2019.03.045  0.731
2019 Rotterman TM, Akhter ET, Lane AR, MacPherson KP, Garcia VV, Tansey MG, Alvarez FJ. Spinal motor circuit synaptic plasticity after peripheral nerve injury depends on microglia activation and a CCR2 mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30833511 DOI: 10.1523/Jneurosci.2945-17.2019  0.74
2019 Barnum C, Tansey MG, Tesi R. P4-662: PHASE 1B OPEN-LABEL, BIOMARKER-DIRECTED STUDY OF THE BRAIN PENETRANT, SOLUBLE SELECTIVE INHIBITOR OF SOLUBLE TUMOR NECROSIS FACTOR XPRO1595 IN PATIENTS WITH MILD TO MODERATE ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1585-P1585. DOI: 10.1016/J.Jalz.2019.09.028  0.321
2019 Elizabeth de Sousa Rodrigues M, Houser MC, Walker DI, Jones D, Chang J, Barnum C, Tansey MG. P4-480: WESTERN DIET PROMOTES CENTRAL INSULIN IMPAIRMENT AND THE DYSREGULATION OF METABOLITES ASSOCIATED WITH ALZHEIMER'S DISEASE: THE ROLE OF SOLUBLE TNF Alzheimer's & Dementia. 15: P1496-P1497. DOI: 10.1016/J.Jalz.2019.08.026  0.75
2019 Eidson LN, Sandor K, Hertzberg V, Cintron AF, Chang J, Kumar V, Verble DD, Tharwani S, Pak H, Brown A, Shin R, Wharton W, Tansey MG. P3-264: PERIPHERAL AND CENTRAL INFLAMMATION DIFFER BY RACE AND ASSOCIATE WITH COGNITIVE PERFORMANCE IN A POPULATION AT RISK FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1037-P1038. DOI: 10.1016/J.Jalz.2019.06.3295  0.343
2019 Tansey MG, Eidson LN, Sandor K, Hertzberg V, Cintron AF, Chang J, Kumar V, Verble DD, Golchani S, Tharwani S, Pak H, Brown A, Shin R, Wharton W. P3-263: PERIPHERAL AND CENTRAL INFLAMMATION ASSOCIATE WITH PHOSPHO-TAU IN A POPULATION AT RISK FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P1037-P1037. DOI: 10.1016/J.Jalz.2019.06.3294  0.368
2019 Eidson LN, MacPherson KP, Herrick MK, Elizabeth de Sousa Rodrigues M, Sniffen LJ, Kelly SD, Hamilton AM, Oliver D, Yang Y, Chang J, Tansey MG. P2-190: SOLUBLE TNF MEDIATES HIGH-FAT-HIGH-CARBOHYDRATE DIET-INDUCED ALTERATIONS IN PERIPHERAL AND BRAIN IMMUNOPHENOTYPE IN A MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P649-P650. DOI: 10.1016/J.Jalz.2019.06.2597  0.777
2018 Bekhbat M, Howell PA, Rowson SA, Kelly SD, Tansey MG, Neigh GN. Chronic adolescent stress sex-specifically alters central and peripheral neuro-immune reactivity in rats. Brain, Behavior, and Immunity. PMID 30550932 DOI: 10.1016/J.Bbi.2018.12.005  0.307
2018 Tansey MG, Romero-Ramos M. Immune system responses in Parkinson's Disease: early and dynamic. The European Journal of Neuroscience. PMID 30474172 DOI: 10.1111/Ejn.14290  0.521
2018 Fournier CN, Houser M, Tansey MG, Glass JD, Hertzberg VS. The gut microbiome and neuroinflammation in amyotrophic lateral sclerosis? Emerging clinical evidence. Neurobiology of Disease. PMID 30321601 DOI: 10.1016/J.Nbd.2018.10.007  0.712
2018 Butkovich LM, Houser MC, Tansey MG. α-Synuclein and Noradrenergic Modulation of Immune Cells in Parkinson's Disease Pathogenesis. Frontiers in Neuroscience. 12: 626. PMID 30258347 DOI: 10.3389/Fnins.2018.00626  0.841
2018 Wright ML, Fournier C, Houser MC, Tansey M, Glass J, Hertzberg VS. Potential Role of the Gut Microbiome in ALS: A Systematic Review. Biological Research For Nursing. 1099800418784202. PMID 29925252 DOI: 10.1177/1099800418784202  0.717
2018 Manfredsson FP, Tansey MG, Golde TE. Challenges in Passive Immunization Strategies to Treat Parkinson Disease. Jama Neurology. PMID 29913004 DOI: 10.1001/Jamaneurol.2018.0346  0.428
2018 Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer LD, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, et al. Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. Journal of Neuroinflammation. 15: 129. PMID 29716614 DOI: 10.1186/S12974-018-1171-Z  0.436
2018 Houser MC, Chang J, Factor SA, Molho ES, Zabetian CP, Hill-Burns EM, Payami H, Hertzberg VS, Tansey MG. Stool immune profiles evince gastrointestinal inflammation in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29572994 DOI: 10.1002/Mds.27326  0.796
2017 Wharton W, Goldstein FC, Tansey MG, Brown AL, Tharwani SD, Verble DD, Cintron A, Kehoe PG. Rationale and Design of the Mechanistic Potential of Antihypertensives in Preclinical Alzheimer's (HEART) Trial. Journal of Alzheimer's Disease : Jad. PMID 29254080 DOI: 10.3233/Jad-161198  0.778
2017 Rose SJ, Harrast P, Donsante C, Fan X, Joers V, Tansey MG, Jinnah HA, Hess EJ. Parkinsonism without dopamine neuron degeneration in aged l-dopa-responsive dystonia knockin mice. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 28949038 DOI: 10.1002/Mds.27169  0.71
2017 Eidson LN, Kannarkat GT, Barnum CJ, Chang J, Chung J, Caspell-Garcia C, Taylor P, Mollenhauer B, Schlossmacher MG, Ereshefsky L, Yen M, Kopil C, Frasier M, Marek K, Hertzberg VS, ... Tansey MG, et al. Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease. Journal of Neuroinflammation. 14: 164. PMID 28821274 DOI: 10.1186/S12974-017-0935-1  0.835
2017 Rangaraju S, Raza SA, Pennati A, Deng Q, Dammer EB, Duong D, Pennington MW, Tansey MG, Lah JJ, Betarbet R, Seyfried NT, Levey AI. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation. Journal of Neuroinflammation. 14: 128. PMID 28651603 DOI: 10.1186/S12974-017-0906-6  0.311
2017 Cook DA, Kannarkat GT, Cintron AF, Butkovich LM, Fraser KB, Chang J, Grigoryan N, Factor SA, West AB, Boss JM, Tansey MG. LRRK2 levels in immune cells are increased in Parkinson's disease. Npj Parkinson's Disease. 3: 11. PMID 28649611 DOI: 10.1038/S41531-017-0010-8  0.819
2017 Houser MC, Tansey MG. The gut-brain axis: is intestinal inflammation a silent driver of Parkinson's disease pathogenesis? Npj Parkinson's Disease. 3: 3. PMID 28649603 DOI: 10.1038/s41531-016-0002-0  0.786
2017 Karamita M, Barnum C, Möbius W, Tansey MG, Szymkowski DE, Lassmann H, Probert L. Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia. Jci Insight. 2. PMID 28422748 DOI: 10.1172/Jci.Insight.87455  0.747
2017 MacPherson KP, Sompol P, Kannarkat GT, Chang J, Sniffen L, Wildner ME, Norris CM, Tansey MG. Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice. Neurobiology of Disease. PMID 28237313 DOI: 10.1016/J.Nbd.2017.02.010  0.812
2017 Greenamyre JT, De Miranda BR, Bucher ML, Singleton AB, Tansey MG. The Gordon Research Seminar & Conference on Parkinson’s disease: state of the Science 200 years after James Parkinson’s essay on the Shaking Palsy Npj Parkinson's Disease. 3. DOI: 10.1038/S41531-017-0028-Y  0.469
2017 Tansey MG, Cintron AF, MacPherson KP, Eidson LN, Goldstein FC, Wharton W. ELEVATED CENTRAL AND PERIPHERAL INFLAMMATORY PROFILES IN A POPULATION AT RISK FOR ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P594. DOI: 10.1016/J.Jalz.2017.07.231  0.796
2017 Tansey MG, MacPherson KP, Eidson LN, Herrick MK, Elizabeth de Sousa Rodrigues M, Oliver D, Kelly SD, Yang Y, Chang J, Sniffen L. [P2-090]: ROLE OF SOLUBLE TNF IN DIET-INDUCED PERIPHERAL AND CENTRAL INFLAMMATION IN A MOUSE MODEL OF ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P641-P641. DOI: 10.1016/J.Jalz.2017.06.739  0.808
2016 de Sousa Rodrigues ME, Bekhbat M, Houser MC, Chang J, Walker DI, Jones DP, Oller do Nascimento CM, Barnum CJ, Tansey MG. Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice. Brain, Behavior, and Immunity. PMID 27592562 DOI: 10.1016/J.Bbi.2016.08.021  0.783
2016 Eidson LN, Inoue K, Young LJ, Tansey MG, Murphy AZ. Toll-Like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27461080 DOI: 10.1038/Npp.2016.131  0.787
2016 Joers V, Tansey MG, Mulas G, Carta AR. Microglial phenotypes in Parkinson's disease and animal models of the disease. Progress in Neurobiology. PMID 27107797 DOI: 10.1016/J.Pneurobio.2016.04.006  0.801
2016 Lee JK, Kannarkat GT, Chung J, Joon Lee H, Graham KL, Tansey MG. RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 13: 24. PMID 26831924 DOI: 10.1186/s12974-016-0491-0  0.788
2016 Nemeth CL, Miller AH, Tansey MG, Neigh GN. Inflammatory mechanisms contribute to microembolism-induced anxiety-like and depressive-like behaviors. Behavioural Brain Research. PMID 26826540 DOI: 10.1016/J.Bbr.2016.01.057  0.32
2016 Kannarkat GT, Tansey MG. Pesticide-induced Immunotoxicity May Underlie Synergistic Gene-environment Interactions that Increase Parkinson's Disease Risk for High-risk Genotype Individuals at rs3129882 in the HLA-DRA Gene Journal of Clinical & Cellular Immunology. 7. DOI: 10.4172/2155-9899.1000474  0.773
2016 Chalermpalanupap T, Bradner J, Chen T, Jerome C, Schroeder J, Lah JJ, Tansey MG, Levey AI, Weinshenker D. P3-069: Elucidating the Relationship Between Hyperphosphorylated TAU and Locus Coeruleus Degeneration in Alzheimer’s Disease Alzheimer's & Dementia. 12: P844-P844. DOI: 10.1016/J.Jalz.2016.06.1727  0.323
2015 Kannarkat GT, Cook DA, Lee JK, Chang J, Chung J, Sandy E, Paul KC, Ritz B, Bronstein J, Factor SA, Boss JM, Tansey MG. Common Genetic Variant Association with Altered HLA Expression, Synergy with Pyrethroid Exposure, and Risk for Parkinson's Disease: An Observational and Case-Control Study. Npj Parkinson's Disease. 1. PMID 27148593 DOI: 10.1038/Npjparkd.2015.2  0.802
2015 Lee JK, Tansey MG. Physiology of RGS10 in Neurons and Immune Cells. Progress in Molecular Biology and Translational Science. 133: 153-67. PMID 26123306 DOI: 10.1016/Bs.Pmbts.2015.01.005  0.662
2015 Moehle MS, Daher JP, Hull TD, Boddu R, Abdelmotilib HA, Mobley J, Kannarkat GT, Tansey MG, West AB. The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins. Human Molecular Genetics. 24: 4250-67. PMID 25926623 DOI: 10.1093/Hmg/Ddv157  0.757
2015 Kannarkat GT, Lee JK, Ramsey CP, Chung J, Chang J, Porter I, Oliver D, Shepherd K, Tansey MG. Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration. Neurobiology of Aging. 36: 1982-93. PMID 25784210 DOI: 10.1016/J.Neurobiolaging.2015.02.006  0.819
2015 Norris CM, Sompol P, MacPherson KP, Tansey MG. P4-205: Peripheral administration of the novel tnf inhibitor xpro1595 improves synaptic function in the 5XFAD model of Alzheimer's disease Alzheimer's & Dementia. 11: P859-P859. DOI: 10.1016/J.Jalz.2015.08.033  0.348
2014 Burgado J, Harrell CS, Eacret D, Reddy R, Barnum CJ, Tansey MG, Miller AH, Wang H, Neigh GN. Two weeks of predatory stress induces anxiety-like behavior with co-morbid depressive-like behavior in adult male mice. Behavioural Brain Research. 275: 120-5. PMID 25200517 DOI: 10.1016/j.bbr.2014.08.060  0.681
2014 Barnum CJ, Chen X, Chung J, Chang J, Williams M, Grigoryan N, Tesi RJ, Tansey MG. Peripheral administration of the selective inhibitor of soluble tumor necrosis factor (TNF) XPro®1595 attenuates nigral cell loss and glial activation in 6-OHDA hemiparkinsonian rats. Journal of Parkinson's Disease. 4: 349-60. PMID 25061061 DOI: 10.3233/JPD-140410  0.776
2014 Alto LT, Chen X, Ruhn KA, Treviño I, Tansey MG. AAV-dominant negative tumor necrosis factor (DN-TNF) gene transfer to the striatum does not rescue medium spiny neurons in the YAC128 mouse model of Huntington's disease. Plos One. 9: e96544. PMID 24824433 DOI: 10.1371/Journal.Pone.0096544  0.843
2014 Ramsey CP, Tansey MG. A survey from 2012 of evidence for the role of neuroinflammation in neurotoxin animal models of Parkinson's disease and potential molecular targets. Experimental Neurology. 256: 126-32. PMID 23726958 DOI: 10.1016/J.Expneurol.2013.05.014  0.495
2014 Karamita M, Barnum C, Tesi R, Szymkowski D, Tansey M, Probert L. Inhibition of soluble TNF protects mice against brain inflammation and demyelination in a cuprizone model for multiple sclerosis Journal of Neuroimmunology. 275: 182. DOI: 10.1016/J.Jneuroim.2014.08.489  0.331
2013 Lee JK, Chung J, Kannarkat GT, Tansey MG. Critical role of regulator G-protein signaling 10 (RGS10) in modulating macrophage M1/M2 activation. Plos One. 8: e81785. PMID 24278459 DOI: 10.1371/Journal.Pone.0081785  0.786
2013 Kannarkat GT, Boss JM, Tansey MG. The role of innate and adaptive immunity in Parkinson's disease. Journal of Parkinson's Disease. 3: 493-514. PMID 24275605 DOI: 10.3233/Jpd-130250  0.807
2013 Chandrasekharan B, Jeppsson S, Pienkowski S, Belsham DD, Sitaraman SV, Merlin D, Kokkotou E, Nusrat A, Tansey MG, Srinivasan S. Tumor necrosis factor-neuropeptide Y cross talk regulates inflammation, epithelial barrier functions, and colonic motility. Inflammatory Bowel Diseases. 19: 2535-46. PMID 24108115 DOI: 10.1097/01.Mib.0000437042.59208.9F  0.38
2013 Harms AS, Tansey MG. Isolation of murine postnatal brain microglia for phenotypic characterization using magnetic cell separation technology. Methods in Molecular Biology (Clifton, N.J.). 1041: 33-9. PMID 23813367 DOI: 10.1007/978-1-62703-520-0_5  0.615
2013 Lee JK, Tansey MG. Microglia isolation from adult mouse brain. Methods in Molecular Biology (Clifton, N.J.). 1041: 17-23. PMID 23813365 DOI: 10.1007/978-1-62703-520-0_3  0.619
2013 Chen X, Chang J, Deng Q, Xu J, Nguyen TA, Martens LH, Cenik B, Taylor G, Hudson KF, Chung J, Yu K, Yu P, Herz J, Farese RV, Kukar T, ... Tansey MG, et al. Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9202-13. PMID 23699531 DOI: 10.1523/Jneurosci.5336-12.2013  0.423
2013 Herzog CD, Brown L, Kruegel BR, Wilson A, Tansey MG, Gage FH, Johnson EM, Bartus RT. Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120). Neurobiology of Disease. 58: 38-48. PMID 23631873 DOI: 10.1016/J.Nbd.2013.04.011  0.567
2013 Nguyen TA, Frank-Cannon T, Martinez TN, Ruhn KA, Marvin M, Casey B, Treviño I, Hong JJ, Goldberg MS, Tansey MG. Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice. Journal of Neuroinflammation. 10: 50. PMID 23622116 DOI: 10.1186/1742-2094-10-50  0.825
2013 Sanchez-Guajardo V, Barnum CJ, Tansey MG, Romero-Ramos M. Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity. Asn Neuro. 5: 113-39. PMID 23506036 DOI: 10.1042/An20120066  0.803
2013 MacPherson K, Tansey M. P1-022: Modulation of peripheral immune cell traffic to the CNS by XPro1595 in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 9: P160-P161. DOI: 10.1016/J.Jalz.2013.05.242  0.792
2012 Dalal NV, Pranski EL, Tansey MG, Lah JJ, Levey AI, Betarbet RS. RNF11 modulates microglia activation through NF-κB signalling cascade. Neuroscience Letters. 528: 174-9. PMID 22975135 DOI: 10.1016/J.Neulet.2012.08.060  0.387
2012 Martinez TN, Chen X, Bandyopadhyay S, Merrill AH, Tansey MG. Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons. Molecular Neurodegeneration. 7: 45. PMID 22973882 DOI: 10.1186/1750-1326-7-45  0.795
2012 Barnum CJ, Tansey MG. Neuroinflammation and non-motor symptoms: the dark passenger of Parkinson's disease? Current Neurology and Neuroscience Reports. 12: 350-8. PMID 22580742 DOI: 10.1007/S11910-012-0283-6  0.781
2012 Lee JK, Chung J, Druey KM, Tansey MG. RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells. Journal of Neurochemistry. 122: 333-43. PMID 22564151 DOI: 10.1111/J.1471-4159.2012.07780.X  0.695
2012 Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, et al. Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. Journal of Proteome Research. 11: 2721-38. PMID 22416763 DOI: 10.1021/Pr2010814  0.31
2012 Barnum CJ, Pace TW, Hu F, Neigh GN, Tansey MG. Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge. Journal of Neuroinflammation. 9: 9. PMID 22248083 DOI: 10.1186/1742-2094-9-9  0.744
2012 Harms AS, Lee JK, Nguyen TA, Chang J, Ruhn KM, Treviño I, Tansey MG. Regulation of microglia effector functions by tumor necrosis factor signaling. Glia. 60: 189-202. PMID 21989628 DOI: 10.1002/Glia.21254  0.766
2012 Chandrasekharan B, Kokkotou E, Tansey M, Srinivasan S. TNF-α Inhibitors Attenuate Neuropeptide Y (NPY) Expression in the Murine Enteric Nervous System: Implications in Inflammation and Colonic Motility Inflammatory Bowel Diseases. 18: S93. DOI: 10.1097/00054725-201212001-00229  0.314
2011 Tran TA, Nguyen AD, Chang J, Goldberg MS, Lee JK, Tansey MG. Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B. Plos One. 6: e23660. PMID 21858193 DOI: 10.1371/Journal.Pone.0023660  0.733
2011 Lee JK, Chung J, McAlpine FE, Tansey MG. Regulator of G-protein signaling-10 negatively regulates NF-κB in microglia and neuroprotects dopaminergic neurons in hemiparkinsonian rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11879-88. PMID 21849548 DOI: 10.1523/Jneurosci.1002-11.2011  0.838
2011 Barnum CJ, Tansey MG. The duality of TNF signaling outcomes in the brain: potential mechanisms? Experimental Neurology. 229: 198-200. PMID 21377463 DOI: 10.1016/J.Expneurol.2011.02.016  0.71
2011 McCoy MK, Ruhn KA, Blesch A, Tansey MG. TNF: a key neuroinflammatory mediator of neurotoxicity and neurodegeneration in models of Parkinson's disease. Advances in Experimental Medicine and Biology. 691: 539-40. PMID 21153359 DOI: 10.1007/978-1-4419-6612-4_56  0.816
2011 Tansey MG, Wyss-Coray T. Workshop summary: roles of the TNF family in neuronal development, function and pathology. Advances in Experimental Medicine and Biology. 691: 537-8. PMID 21153358 DOI: 10.1007/978-1-4419-6612-4_55  0.465
2011 Harms AS, Barnum CJ, Ruhn KA, Varghese S, Treviño I, Blesch A, Tansey MG. Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 46-52. PMID 20959812 DOI: 10.1038/Mt.2010.217  0.84
2011 Barnum C, Tansey MG. Do microglial glucocorticoid receptors protect against loss of dopaminergic neurons in Parkinson's disease? Movement Disorders. 26: 1196. DOI: 10.1002/Mds.23812  0.423
2010 Barnum CJ, Tansey MG. Modeling neuroinflammatory pathogenesis of Parkinson's disease. Progress in Brain Research. 184: 113-32. PMID 20887872 DOI: 10.1016/S0079-6123(10)84006-3  0.802
2010 Tansey MG. Inflammation in neuropsychiatric disease. Neurobiology of Disease. 37: 491-2. PMID 20005951 DOI: 10.1016/J.Nbd.2009.12.004  0.506
2010 Tansey MG, Goldberg MS. Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention. Neurobiology of Disease. 37: 510-8. PMID 19913097 DOI: 10.1016/J.Nbd.2009.11.004  0.555
2010 Tansey MG, Kernie SG. Inflammation in Neurodegenerative Disease and Injury Encyclopedia of Neuroscience. 131-136. DOI: 10.1016/B978-008045046-9.00504-0  0.339
2009 Frank-Cannon TC, Alto LT, McAlpine FE, Tansey MG. Does neuroinflammation fan the flame in neurodegenerative diseases? Molecular Neurodegeneration. 4: 47. PMID 19917131 DOI: 10.1186/1750-1326-4-47  0.821
2009 Tansey MG, Szymkowski DE. The TNF superfamily in 2009: new pathways, new indications, and new drugs. Drug Discovery Today. 14: 1082-8. PMID 19837186 DOI: 10.1016/J.Drudis.2009.10.002  0.358
2009 Lee JK, Tran T, Tansey MG. Neuroinflammation in Parkinson's disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 419-29. PMID 19821032 DOI: 10.1007/S11481-009-9176-0  0.755
2009 McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG. Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Disease. 34: 163-77. PMID 19320056 DOI: 10.1016/J.Nbd.2009.01.006  0.811
2009 Harms A, Varghese S, Ruhn K, Trevino I, Blesch A, Tansey M. P3.050 Role of tumor necrosis factor in the progressive phase of dopaminergic neuron death in a rat model of Parkinson's disease Parkinsonism & Related Disorders. 15: S161. DOI: 10.1016/S1353-8020(09)70614-5  0.635
2008 McAlpine FE, Tansey MG. Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer's disease. Journal of Inflammation Research. 1: 29-39. PMID 22096345 DOI: 10.2147/Jir.S4397  0.804
2008 Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, Hartley M, Treviño I, O'Brien DE, Casey B, Goldberg MS, Tansey MG. Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10825-34. PMID 18945890 DOI: 10.1523/Jneurosci.3001-08.2008  0.833
2008 McCoy MK, Tansey MG. TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease. Journal of Neuroinflammation. 5: 45. PMID 18925972 DOI: 10.1186/1742-2094-5-45  0.804
2008 Lee JK, McCoy MK, Harms AS, Ruhn KA, Gold SJ, Tansey MG. Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8517-28. PMID 18716210 DOI: 10.1523/Jneurosci.1806-08.2008  0.842
2008 McCoy MK, Ruhn KA, Martinez TN, McAlpine FE, Blesch A, Tansey MG. Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1572-9. PMID 18628756 DOI: 10.1038/Mt.2008.146  0.818
2008 Tran TA, McCoy MK, Sporn MB, Tansey MG. The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection. Journal of Neuroinflammation. 5: 14. PMID 18474101 DOI: 10.1186/1742-2094-5-14  0.775
2008 Wrage PC, Tran T, To K, Keefer EW, Ruhn KA, Hong J, Hattangadi S, Treviño I, Tansey MG. The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage. Plos One. 3: e1453. PMID 18197263 DOI: 10.1371/Journal.Pone.0001453  0.779
2008 McCoy MK, Martinez TN, Ruhn KA, Wrage PC, Keefer EW, Botterman BR, Tansey KE, Tansey MG. Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease. Experimental Neurology. 210: 14-29. PMID 18061169 DOI: 10.1016/J.Expneurol.2007.10.011  0.79
2008 Tansey MG, Frank-Cannon TC, McCoy MK, Lee JK, Martinez TN, McAlpine FE, Ruhn KA, Tran TA. Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy? Frontiers in Bioscience : a Journal and Virtual Library. 13: 709-17. PMID 17981581 DOI: 10.2741/2713  0.828
2008 Lee JK, McCoy MK, Harms AS, Ruhn KA, Gold SJ, Tansey MG. Regulator of G-protein signaling (RGS10) regulates microglial response to chronic inflammatory stimuli and impacts dopaminergic neuron survival. The Faseb Journal. 22. DOI: 10.1096/Fasebj.22.1_Supplement.1072.5  0.439
2008 Tansey MG, Wyss-Coray T. Cytokines in CNS inflammation and disease Central Nervous System Diseases and Inflammation. 59-106. DOI: 10.1007/978-0-387-73894-9_5  0.309
2007 Repa JJ, Li H, Frank-Cannon TC, Valasek MA, Turley SD, Tansey MG, Dietschy JM. Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14470-80. PMID 18160655 DOI: 10.1523/Jneurosci.4823-07.2007  0.79
2007 Tansey MG, McCoy MK, Frank-Cannon TC. Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention. Experimental Neurology. 208: 1-25. PMID 17720159 DOI: 10.1016/J.Expneurol.2007.07.004  0.84
2006 McCoy MK, Martinez TN, Ruhn KA, Szymkowski DE, Smith CG, Botterman BR, Tansey KE, Tansey MG. Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9365-75. PMID 16971520 DOI: 10.1523/Jneurosci.1504-06.2006  0.839
2006 Tansey MG, McCoy MK, Frank-Cannon T, McAlpine FE, Botterman BR, Tansey KE. The role of TNF in in vitro and in vivo models of neurodegeneration The Faseb Journal. 20. DOI: 10.1096/Fasebj.20.4.A505-B  0.445
2006 Kukar TG, MacPherson KP, Kannarkat GT, Kline EM, Holler CM, Johnson MA, Taylor GL, Oliver D, Blanchfield JL, Joers VL, Tansey MG. O2-11-03: PROGRANULIN LOSS DYSREGULATES SPLENIC AND PERIPHERAL BLOOD IMMUNE CELL POPULATIONS AND MAY CONTRIBUTE TO NEUROINFLAMMATION AND NEURODEGENERATION IN FRONTOTEMPORAL DEMENTIA Alzheimer's & Dementia. 14: P647-P648. DOI: 10.1016/J.Jalz.2018.06.2702  0.778
2006 Tansey MG, MacPherson KP, Eidson LN, Herrick MK, Elizabeth de Sousa Rodrigues M, Oliver D, Kelly SD, Yang Y, Chang J, Sniffen L. O2-11-02: THE ROLE OF SOLUBLE TNF IN METABOLIC DYSFUNCTION AND BBB ALTERATIONS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P647-P647. DOI: 10.1016/J.Jalz.2018.06.2701  0.797
2006 Tansey MG, McAlpine FE, McCoy MK, Frank-Cannon TC, Meinert KA, Botterman BR, Tansey KE. P3-265: In vivo and in vitro validation of TNF as a key neuroinflammatory mediator of neurotoxicity and neurodegeneration in models of PD and AD Alzheimer's & Dementia. 2: S453-S453. DOI: 10.1016/J.Jalz.2006.05.1534  0.398
2003 Steed PM, Tansey MG, Zalevsky J, Zhukovsky EA, Desjarlais JR, Szymkowski DE, Abbott C, Carmichael D, Chan C, Cherry L, Cheung P, Chirino AJ, Chung HH, Doberstein SK, Eivazi A, et al. Inactivation of TNF signaling by rationally designed dominant-negative TNF variants. Science (New York, N.Y.). 301: 1895-8. PMID 14512626 DOI: 10.1126/Science.1081297  0.334
2001 Encinas M, Tansey MG, Tsui-Pierchala BA, Comella JX, Milbrandt J, Johnson EM. c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1464-72. PMID 11222636 DOI: 10.1523/Jneurosci.21-05-01464.2001  0.511
2001 Encinas M, Tansey MG, Tsui-Pierchala BA, Comella JX, Milbrandt J, Johnson EM. c-Src Is Required for Glial Cell Line-Derived Neurotrophic Factor (GDNF) Family Ligand-Mediated Neuronal Survival via a Phosphatidylinositol-3 Kinase (PI-3K)-Dependent Pathway The Journal of Neuroscience. 21: 1464-1472. DOI: 10.1523/JNEUROSCI.21-05-01464.2001  0.412
2000 Tansey MG, Baloh RH, Milbrandt J, Johnson EM. GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival. Neuron. 25: 611-23. PMID 10774729 DOI: 10.1016/S0896-6273(00)81064-8  0.485
2000 Baloh RH, Tansey MG, Johnson EM, Milbrandt J. Functional mapping of receptor specificity domains of glial cell line-derived neurotrophic factor (GDNF) family ligands and production of GFRalpha1 RET-specific agonists. The Journal of Biological Chemistry. 275: 3412-20. PMID 10652334 DOI: 10.1074/Jbc.275.5.3412  0.499
2000 Tansey MG, Baloh RH, Milbrandt J, Johnson EM. GFRα-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival Neuron. 25: 611-623.  0.412
1998 Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, Leitner ML, Araki T, Johnson EM, Milbrandt J. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron. 21: 1291-302. PMID 9883723 DOI: 10.1016/S0896-6273(00)80649-2  0.487
1998 Baloh RH, Gorodinsky A, Golden JP, Tansey MG, Keck CL, Popescu NC, Johnson EM, Milbrandt J. GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family. Proceedings of the National Academy of Sciences of the United States of America. 95: 5801-6. PMID 9576965 DOI: 10.1073/Pnas.95.10.5801  0.463
1998 Milbrandt J, de Sauvage FJ, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kato AC, Hynes M, et al. Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron. 20: 245-53. PMID 9491986 DOI: 10.1016/S0896-6273(00)80453-5  0.514
1997 Creedon DJ, Tansey MG, Baloh RH, Osborne PA, Lampe PA, Fahrner TJ, Heuckeroth RO, Milbrandt J, Johnson EM. Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 7018-23. PMID 9192684 DOI: 10.1073/Pnas.94.13.7018  0.52
1997 Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM, Milbrandt J. TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron. 18: 793-802. PMID 9182803 DOI: 10.1016/S0896-6273(00)80318-9  0.504
1997 Miller TM, Tansey MG, Johnson EM, Creedon DJ. Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells Journal of Biological Chemistry. 272: 9847-9853. PMID 9092520 DOI: 10.1074/Jbc.272.15.9847  0.483
1996 Tansey MG, Chu GC, Merlie JP. ARIA/HRG regulates AChR epsilon subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway. The Journal of Cell Biology. 134: 465-76. PMID 8707830 DOI: 10.1083/jcb.134.2.465  0.519
1993 Stull JT, Tansey MG, Tang DC, Word RA, Kamm KE. Phosphorylation of myosin light chain kinase: a cellular mechanism for Ca2+ desensitization. Molecular and Cellular Biochemistry. 127: 229-37. PMID 7935354 DOI: 10.1007/Bf01076774  0.503
1992 Stull JT, Tansey MG, Word RA, Kubota Y, Kamm KE. Myosin light chain kinase phosphorylation: regulation of the Ca2+ sensitivity of contractile elements. Advances in Experimental Medicine and Biology. 304: 129-38. PMID 1803895 DOI: 10.1007/978-1-4684-6003-2_12  0.498
1990 Tansey MG, Hori M, Karaki H, Kamm KE, Stull JT. Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle. Febs Letters. 270: 219-21. PMID 2171992 DOI: 10.1016/0014-5793(90)81272-P  0.486
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