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Fadi Jacob - Publications

Affiliations: 
Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
Human stem cells, neural development, brain tumors
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lin X, Wang W, Yang M, Damseh N, de Sousa MML, Jacob F, Lång A, Kristiansen E, Pannone M, Kissova M, Almaas R, Kuśnierczyk A, Siller R, Shahrour M, Al-Ashhab M, et al. A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment. Genome Biology. 24: 216. PMID 37773136 DOI: 10.1186/s13059-023-03037-1  0.483
2023 Jgamadze D, Lim JT, Zhang Z, Harary PM, Germi J, Mensah-Brown K, Adam CD, Mirzakhalili E, Singh S, Gu JB, Blue R, Dedhia M, Fu M, Jacob F, Qian X, et al. Structural and functional integration of human forebrain organoids with the injured adult rat visual system. Cell Stem Cell. 30: 137-152.e7. PMID 36736289 DOI: 10.1016/j.stem.2023.01.004  0.52
2022 Zhou Y, Su Y, Li S, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaene AN, Helbig I, Kessler SK, Lucas T, Salinas RD, et al. Molecular landscapes of human hippocampal immature neurons across lifespan. Nature. PMID 35794479 DOI: 10.1038/s41586-022-04912-w  0.573
2021 Jacob F, Schnoll JG, Song H, Ming GL. Building the brain from scratch: Engineering region-specific brain organoids from human stem cells to study neural development and disease. Current Topics in Developmental Biology. 142: 477-530. PMID 33706925 DOI: 10.1016/bs.ctdb.2020.12.011  0.588
2020 Jacob F, Ming GL, Song H. Generation and biobanking of patient-derived glioblastoma organoids and their application in CAR T cell testing. Nature Protocols. PMID 33169003 DOI: 10.1038/s41596-020-0402-9  0.492
2020 Jacob F, Pather SR, Huang WK, Zhang F, Wong SZH, Zhou H, Cubitt B, Fan W, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, et al. Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium. Cell Stem Cell. PMID 33010822 DOI: 10.1016/J.Stem.2020.09.016  0.621
2020 Jacob F, Pather SR, Huang WK, Wong SZH, Zhou H, Zhang F, Cubitt B, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, de A Torre JC, et al. Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism. Biorxiv : the Preprint Server For Biology. PMID 32766575 DOI: 10.1101/2020.07.28.225151  0.595
2020 Qian X, Su Y, Adam CD, Deutschmann AU, Pather SR, Goldberg EM, Su K, Li S, Lu L, Jacob F, Nguyen PTT, Huh S, Hoke A, Swinford-Jackson SE, Wen Z, et al. Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation. Cell Stem Cell. PMID 32142682 DOI: 10.1016/J.Stem.2020.02.002  0.613
2020 Jacob F, Bennett ML. Modeling neurological disease using human stem cell-derived microglia-like cells transplanted into rodent brains. Lab Animal. PMID 31932736 DOI: 10.1038/S41684-019-0465-9  0.468
2019 Jacob F, Salinas RD, Zhang DY, Nguyen PTT, Schnoll JG, Wong SZH, Thokala R, Sheikh S, Saxena D, Prokop S, Liu DA, Qian X, Petrov D, Lucas T, Chen HI, et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell. PMID 31883794 DOI: 10.1016/J.Cell.2019.11.036  0.54
2019 Makhlin I, Salinas RD, Zhang D, Jacob F, Ming GL, Song H, Saxena D, Dorsey JF, Nasrallah MP, Morrissette JJ, Binder ZA, O'Rourke DM, Desai AS, Brem S, Bagley SJ. Clinical activity of the tyrosine kinase inhibitor osimertinib in -mutant glioblastoma. Cns Oncology. 8: CNS43. PMID 31769726 DOI: 10.2217/Cns-2019-0014  0.5
2019 Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, et al. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nature Genetics. 51: 1252-1262. PMID 31367015 DOI: 10.1038/S41588-019-0472-1  0.551
2019 Salinas R, Zhang D, Jacob F, Nguyen P, Sheikh S, Prokop S, Dorsey JF, Nasrallah M, Brem S, O’Rourke DM, Ming G, Song H. A Patient-Derived Glioblastoma Organoid Model Maintains Intertumoral and Intratumoral Heterogeneity for Therapeutic Testing Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_640  0.505
2019 Nguyen P, Jacob F, Salinas R, Zhang D, Song H, Ming G. Tmod-26. Modeling Glioblastoma By Implantation Of Intact Patient-Derived Organoids Into Rodent Brains Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.1125  0.514
2019 Salinas R, Zhang D, Jacob F, Nguyen P, Sheikh S, Prokop S, Dorsey J, Nasrallah M, Brem S, O’Rourke D, Ming G, Song H. TMOD-25. GLIOBLASTOMA ORGANOIDS: A MODEL SYSTEM FOR PATIENT-SPECIFIC THERAPEUTIC TESTING Neuro-Oncology. 21: vi268-vi268. DOI: 10.1093/Neuonc/Noz175.1124  0.506
2019 Zhang D, Jacob F, Salinas R, Nguyen P, Ming G, Song H. Tmod-13. Modeling The Genetic, Transcriptomic, And Cellular Heterogeneity Of Glioblastoma Using Tumor Organoids Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.1112  0.468
2018 Qian X, Jacob F, Song MM, Nguyen HN, Song H, Ming GL. Generation of human brain region-specific organoids using a miniaturized spinning bioreactor. Nature Protocols. 13: 565-580. PMID 29470464 DOI: 10.1038/Nprot.2017.152  0.595
2017 Ye F, Kang E, Yu C, Qian X, Jacob F, Yu C, Mao M, Poon RYC, Kim J, Song H, Ming GL, Zhang M. DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. Neuron. 96: 1204. PMID 29216452 DOI: 10.1016/J.Neuron.2017.11.034  0.601
2017 Ye F, Kang E, Yu C, Qian X, Jacob F, Yu C, Mao M, Poon RYC, Kim J, Song H, Ming GL, Zhang M. DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. Neuron. PMID 29103808 DOI: 10.1016/J.Neuron.2017.10.010  0.68
2017 Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Doré LC, Jin P, Regot S, et al. Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation. Cell. PMID 28965759 DOI: 10.1016/J.Cell.2017.09.003  0.639
2017 Yoon KJ, Song G, Qian X, Pan J, Xu D, Rho HS, Kim NS, Habela C, Zheng L, Jacob F, Zhang F, Lee EM, Huang WK, Ringeling FR, Vissers C, et al. Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins. Cell Stem Cell. PMID 28826723 DOI: 10.1016/J.Stem.2017.07.014  0.691
2017 Qian X, Nguyen HN, Jacob F, Song H, Ming GL. Using brain organoids to understand Zika virus-induced microcephaly. Development (Cambridge, England). 144: 952-957. PMID 28292840 DOI: 10.1242/Dev.140707  0.599
2017 Sada A, Jacob F, Leung E, Wang S, White BS, Shalloway D, Tumbar T. Defining the stem cell lineages in the mouse inter-follicular epidermis Journal of Dermatological Science. 86: e54. DOI: 10.1016/J.Jdermsci.2017.02.159  0.669
2016 Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, et al. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nature Medicine. PMID 27571349 DOI: 10.1038/Nm.4184  0.506
2016 Sada A, Jacob F, Leung E, Wang S, White BS, Shalloway D, Tumbar T. Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin. Nature Cell Biology. PMID 27183471 DOI: 10.1038/Ncb3359  0.658
2016 Qian X, Nguyen HN, Song MM, Hadiono C, Ogden SC, Hammack C, Yao B, Hamersky GR, Jacob F, Zhong C, Yoon KJ, Jeang W, Lin L, Li Y, Thakor J, et al. Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure. Cell. PMID 27118425 DOI: 10.1016/J.Cell.2016.04.032  0.734
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