Emiel F.M. Wouters, MD, PhD - Publications

Affiliations: 
Maastricht University, Maastricht, Limburg, Netherlands 

254 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Schiffers C, van de Wetering C, Bauer RA, Habibovic A, Hristova M, Dustin CM, Lambrichts S, Vacek PM, Wouters EF, Reynaert NL, van der Vliet A. Downregulation of epithelial DUOX1 in Chronic Obstructive Pulmonary Disease contributes to disease pathogenesis. Jci Insight. PMID 33301419 DOI: 10.1172/jci.insight.142189  0.334
2020 Wouters EF, Posthuma R, Koopman M, Liu WY, Sillen MJ, Hajian B, Sastry M, Spruit MA, Franssen FM. An update on pulmonary rehabilitation techniques for patients with chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine. 14: 149-161. PMID 31931636 DOI: 10.1080/17476348.2020.1700796  0.343
2020 Auffray C, Balling R, Blomberg N, Bonaldo MC, Boutron B, Brahmachari S, Bréchot C, Cesario A, Chen S, Clément K, Danilenko D, Di Meglio A, Gelemanović A, Goble C, Gojobori T, ... ... Wouters E, et al. COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight F1000research. 9: 1130. DOI: 10.12688/F1000Research.26098.1  0.302
2019 Janssen R, Wouters EF, Janssens W, Daamen WF, Hagedoorn P, de Wit HA, Serré J, Gayan-Ramirez G, Franssen FM, Reynaert NL, von der Thüsen JH, Frijlink HW. Copper-Heparin Inhalation Therapy To Repair Emphysema: A Scientific Rationale. International Journal of Chronic Obstructive Pulmonary Disease. 14: 2587-2602. PMID 32063701 DOI: 10.2147/Copd.S228411  0.39
2019 Franssen FM, Alter P, Bar N, Benedikter BJ, Iurato S, Maier D, Maxheim M, Roessler FK, Spruit MA, Vogelmeier CF, Wouters EF, Schmeck B. Personalized medicine for patients with COPD: where are we? International Journal of Chronic Obstructive Pulmonary Disease. 14: 1465-1484. PMID 31371934 DOI: 10.2147/Copd.S175706  0.459
2019 Liu WY, Meijer K, Delbressine J, Willems P, Wouters E, Spruit M. Effects of Pulmonary Rehabilitation on Gait Characteristics in Patients with COPD. Journal of Clinical Medicine. 8. PMID 30959769 DOI: 10.3390/Jcm8040459  0.435
2019 Spruit MA, Rochester C, Pitta F, Kenn K, Schols AMWJ, Hart N, Wouters E, Nava S, Dreher M, Janssen DJA, Johnson MJ, Curtis JR, Sastry M, Franssen F. Pulmonary rehabilitation, physical activity, respiratory failure and palliative respiratory care. Thorax. PMID 30872364 DOI: 10.1136/Thoraxjnl-2018-212044  0.364
2019 Topalovic M, Das N, Burgel PR, Daenen M, Derom E, Haenebalcke C, Janssen R, Kerstjens HAM, Liistro G, Louis R, Ninane V, Pison C, Schlesser M, Vercauter P, Vogelmeier CF, ... Wouters E, et al. Artificial intelligence outperforms pulmonologists in the interpretation of pulmonary function tests. The European Respiratory Journal. PMID 30765505 DOI: 10.1183/13993003.01660-2018  0.307
2019 Breyer-Kohansal R, Hartl S, Burghuber OC, Urban M, Schrott A, Agusti A, Sigsgaard T, Vogelmeier C, Wouters E, Studnicka M, Breyer M. The LEAD (Lung, Heart, Social, Body) Study: Objectives, Methodology, and External Validity of the Population-Based Cohort Study. Journal of Epidemiology. 29: 315-324. PMID 30344197 DOI: 10.2188/Jea.Je20180039  0.332
2019 Herck MV, Antons J, Vercoulen J, Goërtz Y, Ebadi Z, Burtin C, Janssen D, Thong M, Otker J, Coors A, Sprangers M, Muris J, Wouters E, Prins J, Spruit M, et al. Pulmonary rehabilitation reduces fatigue in COPD: a responder analysis European Respiratory Journal. 54: 1. DOI: 10.1183/13993003.Congress-2019.Pa573  0.41
2019 Houben C, Spruit M, Luyten H, Pennings H, Boogaart Vvd, Creemers J, Wesseling G, Wouters E, Janssen D. OP68 A cluster-randomized trial of a nurse-led advance care planning session in patients with COPD and their loved ones Bmj. 9. DOI: 10.1136/Spcare-2019-Acpicongressabs.68  0.349
2018 Janssen R, Piscaer I, Wouters EF. Inhalation therapy for repairing damaged elastin fibers and decelerating elastinolysis in chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine. 1-12. PMID 29600734 DOI: 10.1080/17476348.2018.1460206  0.317
2018 Kahnert K, Alter P, Young D, Lucke T, Heinrich J, Huber RM, Behr J, Wacker M, Biertz F, Watz H, Bals R, Welte T, Wirtz H, Herth F, Vestbo J, ... Wouters EF, et al. The revised GOLD 2017 COPD categorization in relation to comorbidities. Respiratory Medicine. 134: 79-85. PMID 29413512 DOI: 10.1055/S-0037-1619396  0.374
2018 De Brouwer B, Piscaer I, Von Der Thusen JH, Grutters JC, Schutgens RE, Wouters EF, Janssen R. Should vitamin K be supplemented instead of antagonised in patients with idiopathic pulmonary fibrosis? Expert Review of Respiratory Medicine. 1-7. PMID 29303380 DOI: 10.1080/17476348.2018.1424544  0.308
2018 Topalovic M, Das N, Burgel P, Daenen M, Derom E, Haenebalcke C, Janssen R, Kerstjens H, Liistro G, Louis R, Ninane V, Pison C, Schlesser M, Vercauter P, Vogelmeier C, ... Wouters E, et al. Artificial intelligence improves experts in reading pulmonary function tests European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Pa5290  0.335
2018 Buekers J, Aerts J, Theunis J, Vaes A, Wouters E, Spruit M, Boever PD. Multi-night continuous nocturnal oxygen saturation measurements in patients with COPD European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa4054  0.318
2018 Goërtz Y, Spruit M, Hul AV', Peters J, Herck MV, Nakken N, Djamin R, Burtin C, Thong M, Coors A, Meertens-Kerris Y, Wouters E, Prins J, Franssen F, Muris J, et al. Late Breaking Abstract - Fatigue is highly prevalent in patients with COPD and correlates poorly with the airflow limitation European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa3823  0.416
2018 Conemans L, Agterhuis D, Franssen F, Spruit M, Wouters E, Vanfleteren L. Effects of pulmonary rehabilitation in patients with asthma European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Pa2043  0.396
2018 Wetering Cvd, Aboushousha R, Chia SB, Manuel A, Bates J, Velden Jvd, Reynaert N, Vliet Avd, Wouters E, Janssen-Heininger Y. Glutathione-S-transferase π promotes interleukin-1β induced pulmonary inflammation in association with S-glutathionylation of the glycolysis regulator, pyruvate kinase M2 Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.067  0.331
2017 Houben-Wilke S, Augustin IM, Wouters BB, Stevens R, Janssen DJA, Spruit MA, Vanfleteren LE, Franssen FM, Wouters EF. The patient with a complex chronic respiratory disease: a specialist of his own life? Expert Review of Respiratory Medicine. PMID 29025350 DOI: 10.1080/17476348.2017.1392242  0.422
2017 Braeken DC, Rohde GG, Franssen FM, Driessen JH, van Staa TP, Souverein PC, Wouters EF, de Vries F. Risk of community-acquired pneumonia in chronic obstructive pulmonary disease stratified by smoking status: a population-based cohort study in the United Kingdom. International Journal of Chronic Obstructive Pulmonary Disease. 12: 2425-2432. PMID 28860737 DOI: 10.2147/Copd.S138435  0.359
2017 Mesquita R, Spina G, Pitta F, Donaire-Gonzalez D, Deering BM, Patel MS, Mitchell KE, Alison J, van Gestel AJ, Zogg S, Gagnon P, Abascal-Bolado B, Vagaggini B, Garcia-Aymerich J, Jenkins SC, ... ... Wouters EF, et al. Physical activity patterns and clusters in 1001 patients with COPD. Chronic Respiratory Disease. 14: 256-269. PMID 28774199 DOI: 10.1177/1479972316687207  0.342
2017 Uszko-Lencer NH, Mesquita R, Janssen E, Werter C, Brunner-La Rocca HP, Pitta F, Wouters EF, Spruit MA. Reliability, construct validity and determinants of 6-minute walk test performance in patients with chronic heart failure. International Journal of Cardiology. PMID 28377186 DOI: 10.1016/J.Ijcard.2017.02.109  0.33
2017 Kuklisova Z, Tkacova R, Joppa P, Wouters E, Sastry M. Severity of nocturnal hypoxia and daytime hypercapnia predicts CPAP failure in patients with COPD and obstructive sleep apnea overlap syndrome Sleep Medicine. 30: 139-145. PMID 28215237 DOI: 10.1016/J.Sleep.2016.02.012  0.419
2017 Martin M, Almeras N, Després JP, Coxson HO, Washko GR, Vivodtzev I, Wouters EF, Rutten E, Williams MC, Murchison JT, MacNee W, Sin DD, Maltais F. Ectopic fat accumulation in patients with COPD: an ECLIPSE substudy. International Journal of Chronic Obstructive Pulmonary Disease. 12: 451-460. PMID 28203068 DOI: 10.2147/Copd.S124750  0.384
2017 Cleutjens FA, Spruit MA, Ponds RW, Vanfleteren LE, Franssen FM, Dijkstra JB, Gijsen C, Wouters EF, Janssen DJ. The Impact of Cognitive Impairment on Efficacy of Pulmonary Rehabilitation in Patients With COPD. Journal of the American Medical Directors Association. PMID 28108209 DOI: 10.1016/J.Jamda.2016.11.016  0.435
2017 Nakken N, Janssen DJ, van Vliet M, de Vries GJ, Clappers-Gielen GA, Michels AJ, Muris JW, Vercoulen JH, Wouters EF, Spruit MA. Gender differences in partners of patients with COPD and their perceptions about the patients. International Journal of Chronic Obstructive Pulmonary Disease. 12: 95-104. PMID 28096665 DOI: 10.2147/Copd.S118871  0.432
2017 Mesquita R, Nakken N, Janssen DJ, van den Bogaart EH, Delbressine JM, Essers JM, Meijer K, van Vliet M, de Vries GJ, Muris JW, Pitta F, Wouters EF, Spruit MA. Activity levels and exercise motivation in COPD patients and their resident loved ones. Chest. PMID 28087303 DOI: 10.1016/J.Chest.2016.12.021  0.352
2017 Kahnert K, Lucke T, Biertz F, Lechner A, Watz H, Alter P, Bals R, Behr J, Holle R, Huber RM, Karrasch S, Stubbe B, Wacker M, Söhler S, Wouters EF, et al. Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort. Respiratory Research. 18: 14. PMID 28086884 DOI: 10.1186/S12931-016-0499-0  0.319
2017 Spina G, Spruit MA, Alison J, Benzo RP, Calverley PM, Clarenbach CF, Costello RW, Donaire-Gonzalez D, Dürr S, Garcia-Aymerich J, van Gestel AJ, Gramm M, Hernandes NA, Hill K, Hopkinson NS, ... ... Wouters EF, et al. Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity. Thorax. PMID 28082529 DOI: 10.1136/Thoraxjnl-2016-208900  0.32
2017 McDonald MN, Won S, Mattheisen M, Castaldi PJ, Cho MH, Rutten E, Hardin M, Yip WK, Rennard SI, Lomas DA, Wouters EF, Agusti A, Casaburi R, Lange CP, O'Connor G, et al. Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Journal of Cachexia, Sarcopenia and Muscle. PMID 28044437 DOI: 10.1002/Jcsm.12171  0.344
2017 Vaes A, Spruit M, Wouters E, Theunis J, Boever PD, Standaert A, Elen B. Retinal image analysis in patients with COPD European Respiratory Journal. DOI: 10.1183/1393003.Congress-2017.Oa4869  0.301
2017 Wouters E, Magnussen H, Rodríguez-Roisin R, Tetzlaff K, Bell S, Calverley P. Lung-Function Profile Before and After the First Moderate to Severe Exacerbation During the WISDOM Study Pneumologie. 71: 243. DOI: 10.1055/S-0037-1598314  0.323
2016 Houben CH, Spruit MA, Schols JM, Wouters EF, Janssen DJ. Instability of willingness to accept life-sustaining treatments of patients with advanced chronic organ failure during one year. Chest. PMID 28007621 DOI: 10.1016/J.Chest.2016.12.003  0.325
2016 Houben-Wilke S, Spruit MA, Uszko-Lencer NH, Otkinska G, Vanfleteren LE, Jones PW, Wouters EF, Franssen FM. Echocardiographic abnormalities and their impact on health status in patients with COPD referred for pulmonary rehabilitation. Respirology (Carlton, Vic.). PMID 28001000 DOI: 10.1111/Resp.12968  0.422
2016 Cleutjens FA, Pedone C, Janssen DJ, Wouters EF, Incalzi RA. Sleep quality disturbances and cognitive functioning in elderly patients with COPD. Erj Open Research. 2. PMID 27957482 DOI: 10.1183/23120541.00054-2016  0.328
2016 Bellinghausen C, Rohde GG, Savelkoul PH, Wouters EF, Stassen FR. Viral-Bacterial interactions in the respiratory tract. The Journal of General Virology. PMID 27902340 DOI: 10.1099/Jgv.0.000627  0.305
2016 Kayyali R, Odeh B, Frerichs I, Davies N, Perantoni E, D'arcy S, Vaes AW, Chang J, Spruit MA, Deering B, Philip N, Siva R, Kaimakamis E, Chouvarda I, Pierscionek B, ... ... Wouters EF, et al. COPD care delivery pathways in five European Union countries: mapping and health care professionals' perceptions. International Journal of Chronic Obstructive Pulmonary Disease. 11: 2831-2838. PMID 27881915 DOI: 10.2147/Copd.S104136  0.314
2016 Eurlings IM, Reynaert NL, van de Wetering C, Aesif SW, Mercken EM, de Cabo R, van der Velden JL, Janssen-Heininger YM, Wouters EF, Dentener MA. Involvement of JNK in TNFα Driven Remodelling. American Journal of Respiratory Cell and Molecular Biology. PMID 27875656 DOI: 10.1183/13993003.Congress-2015.Pa5058  0.346
2016 Nakken N, Janssen DJ, van den Bogaart EH, van Vliet M, de Vries GJ, Bootsma GP, Gronenschild MH, Delbressine JM, Muris JW, Wouters EF, Spruit MA. Patient versus proxy-reported problematic activities of daily life in patients with COPD. Respirology (Carlton, Vic.). PMID 27731530 DOI: 10.1111/Resp.12915  0.382
2016 Andrianopoulos V, Celli BR, Franssen FM, Pinto-Plata VM, Calverley PM, Vanfleteren LE, Vogiatzis I, Vestbo J, Agusti A, Bakke PS, Rennard SI, MacNee W, Tal-Singer R, Yates JC, Wouters EF, et al. Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study. Respiratory Medicine. 119: 87-95. PMID 27692154 DOI: 10.1016/J.Rmed.2016.08.023  0.453
2016 Smid DE, Franssen FM, Houben-Wilke S, Vanfleteren LE, Janssen DJ, Wouters EF, Spruit MA. Responsiveness and MCID Estimates for CAT, CCQ, and HADS in Patients With COPD Undergoing Pulmonary Rehabilitation: A Prospective Analysis. Journal of the American Medical Directors Association. PMID 27624705 DOI: 10.1016/J.Jamda.2016.08.002  0.472
2016 Liu WY, Meijer K, Delbressine JM, Willems PJ, Franssen FM, Wouters EF, Spruit MA. Reproducibility and Validity of the 6-Minute Walk Test Using the Gait Real-Time Analysis Interactive Lab in Patients with COPD and Healthy Elderly. Plos One. 11: e0162444. PMID 27607426 DOI: 10.1371/Journal.Pone.0162444  0.423
2016 Franssen FM, Wouters EF, Vanfleteren LE. Indacaterol-Glycopyrronium for COPD. The New England Journal of Medicine. 375: 898-9. PMID 27579650 DOI: 10.1056/NEJMc1609305  0.319
2016 Stolz D, Leeming DJ, Edfort Kristensen JH, Karsdal MA, Boersma W, Louis R, Milenkovic B, Kostikas K, Blasi F, Aerts J, Sand JM, Wouters EF, Rohde G, Prat C, Torres A, et al. Systemic biomarkers of collagen and elastin turnover are associated with clinically relevant outcomes in COPD. Chest. PMID 27575358 DOI: 10.1016/J.Chest.2016.08.1440  0.416
2016 Houben-Wilke S, Jörres RA, Bals R, Franssen FM, Gläser S, Holle R, Karch A, Koch A, Magnussen H, Obst A, Schulz H, Spruit MA, Wacker ME, Welte T, Wouters EF, et al. Peripheral Artery Disease and its Clinical Relevance in Patients with COPD in the COSYCONET Study. American Journal of Respiratory and Critical Care Medicine. PMID 27532739 DOI: 10.1164/Rccm.201602-0354Oc  0.377
2016 Janssen DJ, Wilke S, Smid DE, Franssen FM, Augustin IM, Wouters EF, Spruit MA. Relationship between pulmonary rehabilitation and care dependency in COPD. Thorax. PMID 27402003 DOI: 10.1136/Thoraxjnl-2016-208836  0.368
2016 Reynaert NL, Gopal P, Rutten EP, Wouters EF, Schalkwijk CG. Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease. The International Journal of Biochemistry & Cell Biology. PMID 27373680 DOI: 10.1016/J.Biocel.2016.06.016  0.341
2016 Ubags ND, Stapleton RD, Vernooy JH, Burg E, Bement J, Hayes CM, Ventrone S, Zabeau L, Tavernier J, Poynter ME, Parsons PE, Dixon AE, Wargo MJ, Littenberg B, Wouters EF, et al. Hyperleptinemia is associated with impaired pulmonary host defense. Jci Insight. 1. PMID 27347561 DOI: 10.1172/Jci.Insight.82101  0.337
2016 Bellinghausen C, Gulraiz F, Heinzmann AC, Dentener MA, Savelkoul PH, Wouters EF, Rohde GG, Stassen FR. Exposure to common respiratory bacteria alters the airway epithelial response to subsequent viral infection. Respiratory Research. 17: 68. PMID 27259950 DOI: 10.1186/S12931-016-0382-Z  0.343
2016 Van den Heuvel LA, Spruit MA, Schols JM, Hoving C, Wouters EF, Janssen DJ. Barriers and facilitators to end-of-life communication in advanced chronic organ failure. International Journal of Palliative Nursing. 22: 222-229. PMID 27233009 DOI: 10.12968/Ijpn.2016.22.5.222  0.304
2016 Mesquita R, Wilke S, Smid DE, Janssen DJ, Franssen FM, Probst VS, Wouters EF, Muris JW, Pitta F, Spruit MA. Measurement properties of the Timed Up & Go test in patients with COPD. Chronic Respiratory Disease. PMID 27165963 DOI: 10.1177/1479972316647178  0.403
2016 Joppa P, Tkacova R, Franssen FM, Hanson C, Rennard SI, Silverman EK, McDonald MN, Calverley PM, Tal-Singer R, Spruit MA, Kenn K, Wouters EF, Rutten EP. Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease. Journal of the American Medical Directors Association. PMID 27161848 DOI: 10.1016/J.Jamda.2016.03.020  0.392
2016 Perkins TN, Dentener MA, Stassen FR, Rohde GG, Mossman BT, Wouters EF, Reynaert NL. Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells. Toxicology and Applied Pharmacology. 301: 61-70. PMID 27095093 DOI: 10.1016/J.Taap.2016.04.003  0.306
2016 Watz H, Tetzlaff K, Wouters EF, Kirsten A, Magnussen H, Rodriguez-Roisin R, Vogelmeier C, Fabbri LM, Chanez P, Dahl R, Disse B, Finnigan H, Calverley PM. Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial. The Lancet. Respiratory Medicine. PMID 27066739 DOI: 10.1016/S2213-2600(16)00100-4  0.436
2016 Janssen DJ, Wouters EF, Parra YL, Stakenborg K, Franssen FM. Prevalence of thoracic pain in patients with chronic obstructive pulmonary disease and relationship with patient characteristics: a cross-sectional observational study. Bmc Pulmonary Medicine. 16: 47. PMID 27052199 DOI: 10.1186/S12890-016-0210-8  0.444
2016 Rabinovich RA, Miller BE, Wrobel K, Ranjit K, Williams MC, Drost E, Edwards LD, Lomas DA, Rennard SI, Agustí A, Tal-Singer R, Vestbo J, Wouters EF, John M, van Beek EJ, et al. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD. The European Respiratory Journal. PMID 27009168 DOI: 10.1183/13993003.01824-2015  0.402
2016 Jones PW, Watz H, Wouters EF, Cazzola M. COPD: the patient perspective. International Journal of Chronic Obstructive Pulmonary Disease. 11: 13-20. PMID 26937186 DOI: 10.2147/Copd.S85977  0.446
2016 Verberkt CA, van den Beuken-van Everdingen MH, Franssen FM, Dirksen CD, Schols JM, Wouters EF, Janssen DJ. A randomized controlled trial on the benefits and respiratory adverse effects of morphine for refractory dyspnea in patients with COPD: Protocol of the MORDYC study. Contemporary Clinical Trials. 47: 228-34. PMID 26825021 DOI: 10.1016/J.Cct.2016.01.007  0.417
2016 Nakken N, Spruit MA, van den Bogaart EH, van Vliet M, de Vries GJ, Custers FL, Vercoulen JH, Asijee GM, Muris JW, Vanfleteren LE, Franssen FM, Wouters EF, Janssen DJ. Health Status and Morbidities in Resident Relatives of Patients With COPD. Journal of the American Medical Directors Association. PMID 26805754 DOI: 10.1016/J.Jamda.2015.12.012  0.444
2016 Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, ... ... Wouters EF, et al. Exome Array Analysis Identifies A Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 26771213 DOI: 10.1164/Rccm.201510-2053Oc  0.38
2016 Rutten EP, Gopal P, Wouters EF, Franssen FM, Hageman GJ, Vanfleteren LE, Spruit MA, Reynaert NL. Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD. Chest. 149: 53-61. PMID 26066545 DOI: 10.1378/Chest.15-0645  0.326
2016 Cleutjens F, Spruit M, Ponds R, Vanfleteren L, Franssen F, Gijsen C, Dijkstra J, Wouters E, Janssen D. Cognitive impairment and clinical characteristics in patients with COPD European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa3746  0.425
2016 Cleutjens F, Franssen F, Spruit M, Vanfleteren L, Gijsen C, Dijkstra J, Ponds R, Wouters E, Janssen D. Domain-specific cognitive impairment in patients with COPD and control subjects European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa3742  0.349
2016 Beijers R, Bool Cvd, Borst Bvd, Franssen F, Wouters E, Schols A. Cardiometabolic risk profile in muscle wasted COPD patients with abdominal obesity and the effect of pulmonary rehabilitation European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa3590  0.382
2016 Houben C, Spruit M, Wouters E, Pennings H, Creemers J, Wesseling G, Boogaart VKd, Janssen D. Preferences for end-of-life care in patients with COPD European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1620  0.348
2016 Liu W, Spruit M, Delbressine J, Willems P, Franssen F, Wouters E, Meijer K. Gait pattern in patients with COPD and controls during the 6-minute walk test European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1571  0.322
2016 Braeken D, Wilke S, Smid D, Rohde G, Drijkoningen J, Wouters E, Spruit M, Franssen F. The impact of exacerbations on adherence and outcomes of pulmonary rehabilitation in patients with COPD European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa4812  0.39
2016 Houben C, Spruit M, Wouters E, Pennings H, Creemers J, Wesseling G, Boogaart VKd, Janssen D. Preferences for death and dying in patients with COPD European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa293  0.373
2016 Bool CVd, Ruten E, Helvoort Av, Franssen F, Wouters E, Schols A. Physiological effects of nutritional supplementation as adjunct to exercise training in COPD patients with low muscle mass. The double blind, placebo controlled multi-centre NUTRAIN-trial European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa266  0.334
2016 Braeken D, Rohde G, Franssen F, Driessen J, Staa Tv, Souverein P, Wouters E, Vries Fd. Risk of CAP in COPD stratified by smoking status: A population-based cohort study in the UK European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa1504  0.357
2016 Wouters E, Magnussen H, Rodriguez-Roisin R, Tetzlaff K, Bell S, Calverley PA. Lung-Function Profile Before And After The First Moderate To Severe Exacerbation During The Wisdom Study Thorax. 71. DOI: 10.1136/Thoraxjnl-2016-209333.440  0.371
2015 Barnes PJ, Burney PG, Silverman EK, Celli BR, Vestbo J, Wedzicha JA, Wouters EF. Chronic obstructive pulmonary disease. Nature Reviews. Disease Primers. 1: 15076. PMID 27189863 DOI: 10.1038/nrdp.2015.76  0.351
2015 Maatman RC, Spruit MA, VAN Melick PP, Peeters JP, Rutten EP, Vanfleteren LE, Wouters EF, Franssen FM. Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD. Respirology (Carlton, Vic.). PMID 26647921 DOI: 10.1111/Resp.12700  0.327
2015 Stoilkova-Hartmann A, Janssen DJ, Franssen FM, Wouters EF. Differences in change in coping styles between good responders, moderate responders and non-responders to pulmonary rehabilitation. Respiratory Medicine. 109: 1540-5. PMID 26603339 DOI: 10.1016/J.Rmed.2015.10.008  0.439
2015 Hardin M, Cho MH, McDonald ML, Wan E, Lomas DA, Coxson HO, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, et al. A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease. The Pharmacogenomics Journal. PMID 26503814 DOI: 10.1038/Tpj.2015.65  0.354
2015 Spruit MA, Augustin IM, Vanfleteren LE, Janssen DJ, Gaffron S, Pennings HJ, Smeenk F, Pieters W, van den Bergh JJ, Michels AJ, Groenen MT, Rutten EP, Wouters EF, Franssen FM. Differential response to pulmonary rehabilitation in COPD: multidimensional profiling. The European Respiratory Journal. 46: 1625-35. PMID 26453626 DOI: 10.1183/13993003.00350-2015  0.433
2015 Nakken N, Janssen DJ, van den Bogaart EH, Wouters EF, Franssen FM, Vercoulen JH, Spruit MA. Informal caregivers of patients with COPD: Home Sweet Home? European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 498-504. PMID 26324811 DOI: 10.1183/16000617.00010114  0.385
2015 Smid DE, Wilke S, Jones PW, Muris JW, Wouters EF, Franssen FM, Spruit MA. Impact of cardiovascular comorbidities on COPD Assessment Test (CAT) and its responsiveness to pulmonary rehabilitation in patients with moderate to very severe COPD: protocol of the Chance study. Bmj Open. 5: e007536. PMID 26198426 DOI: 10.1136/Bmjopen-2014-007536  0.462
2015 Vaes AW, Meijer K, Delbressine JM, Wiechert J, Willems P, Wouters EF, Franssen FM, Spruit MA. Efficacy of walking aids on self-paced outdoor walking in individuals with COPD: A randomized cross-over trial. Respirology (Carlton, Vic.). 20: 932-9. PMID 26150231 DOI: 10.1111/Resp.12570  0.375
2015 Andrianopoulos V, Wouters EF, Pinto-Plata VM, Vanfleteren LE, Bakke PS, Franssen FM, Agusti A, MacNee W, Rennard SI, Tal-Singer R, Vogiatzis I, Vestbo J, Celli BR, Spruit MA. Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study. Respiratory Medicine. 109: 1138-46. PMID 26143282 DOI: 10.1016/J.Rmed.2015.06.013  0.351
2015 Agustí A, Rennard S, Edwards LD, MacNee W, Wouters E, Miller B, Tal-Singer R, Mullerova H, Celli B. Clinical and prognostic heterogeneity of C and D GOLD groups. The European Respiratory Journal. 46: 250-4. PMID 26130780 DOI: 10.1183/09031936.00012215  0.397
2015 Janssen DJ, Wouters EF, Spruit MA. Psychosocial consequences of living with breathlessness due to advanced disease. Current Opinion in Supportive and Palliative Care. 9: 232-7. PMID 26125305 DOI: 10.1097/Spc.0000000000000146  0.417
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, ... ... Wouters EF, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 159-72. PMID 26028628 DOI: 10.1183/16000617.00000315  0.366
2015 Stoilkova-Hartmann A, Janssen DJ, Franssen FM, Spruit MA, Wouters EF. Attitudes of healthcare professionals providing pulmonary rehabilitation toward partnership in care. Heart & Lung : the Journal of Critical Care. 44: 347-52. PMID 26025762 DOI: 10.1016/J.Hrtlng.2015.05.003  0.377
2015 Cleutjens F, Triest F, Wilke S, Vanfleteren LE, Franssen FM, Janssen DJ, Rutten EP, Spruit MA, Wouters EF. New insights in chronic obstructive pulmonary disease and comorbidity. American Journal of Respiratory and Critical Care Medicine. 191: 1081-2. PMID 25932764 DOI: 10.1164/Rccm.201412-2296Rr  0.341
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, ... ... Wouters EF, et al. An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 191: e4-e27. PMID 25830527 DOI: 10.1164/Rccm.201501-0044St  0.389
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, ... ... Wouters EF, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. The European Respiratory Journal. 45: 879-905. PMID 25829431 DOI: 10.1183/09031936.00009015  0.366
2015 Wilke S, Jones PW, Müllerova H, Vestbo J, Tal-Singer R, Franssen FM, Agusti A, Bakke P, Calverley PM, Coxson HO, Crim C, Edwards LD, Lomas DA, MacNee W, Rennard SI, ... ... Wouters EF, et al. One-year change in health status and subsequent outcomes in COPD. Thorax. 70: 420-5. PMID 25782757 DOI: 10.1136/Thoraxjnl-2014-205697  0.304
2015 Andrianopoulos V, Holland AE, Singh SJ, Franssen FM, Pennings HJ, Michels AJ, Smeenk FW, Vogiatzis I, Wouters EF, Spruit MA. Six-minute walk distance in patients with chronic obstructive pulmonary disease: Which reference equations should we use? Chronic Respiratory Disease. 12: 111-9. PMID 25754856 DOI: 10.1177/1479972315575201  0.317
2015 Nakken N, Spruit MA, Wouters EF, Schols JM, Janssen DJ. Family caregiving during 1-year follow-up in individuals with advanced chronic organ failure. Scandinavian Journal of Caring Sciences. 29: 734-44. PMID 25648714 DOI: 10.1111/Scs.12204  0.369
2015 Rennard SI, Locantore N, Delafont B, Tal-Singer R, Silverman EK, Vestbo J, Miller BE, Bakke P, Celli B, Calverley PM, Coxson H, Crim C, Edwards LD, Lomas DA, MacNee W, ... Wouters EF, et al. Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Annals of the American Thoracic Society. 12: 303-12. PMID 25642832 DOI: 10.1513/Annalsats.201403-125Oc  0.442
2015 Houben CH, Spruit MA, Schols JM, Wouters EF, Janssen DJ. Patient-Clinician Communication About End-of-Life Care in Patients With Advanced Chronic Organ Failure During One Year. Journal of Pain and Symptom Management. 49: 1109-15. PMID 25623920 DOI: 10.1016/J.Jpainsymman.2014.12.008  0.336
2015 Hoffman S, Nolin J, McMillan D, Wouters E, Janssen-Heininger Y, Reynaert N. Thiol redox chemistry: role of protein cysteine oxidation and altered redox homeostasis in allergic inflammation and asthma. Journal of Cellular Biochemistry. 116: 884-92. PMID 25565397 DOI: 10.1002/Jcb.25017  0.305
2015 Engel M, Nowacki RM, Boden P, Reiss LK, Uhlig S, Reynaert NL, Gopal P, Wouters EF, Willems CH, Kloosterboer N, Wolfs TG, Zimmermann LJ, Vos GD, Kramer BW. The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome. Lung. 193: 97-103. PMID 25503749 DOI: 10.1007/S00408-014-9670-X  0.323
2015 Wilke S, Spruit MA, Wouters EF, Schols JM, Franssen FM, Janssen DJ. Determinants of 1-year changes in disease-specific health status in patients with advanced chronic obstructive pulmonary disease: A 1-year observational study. International Journal of Nursing Practice. 21: 239-48. PMID 24666609 DOI: 10.1111/Ijn.12265  0.44
2015 Konings G, Reynaert N, Romano A, Wouters E, Vernooy J. Distinct localization of estrogen receptors in lungs of severe COPD patients European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa869  0.387
2015 Konings G, Reynaert N, Romano A, Bracke K, Brusselle G, Wouters E, Vernooy J. Expression of estrogen receptors and estrogen metabolism genes in lungs of COPD patients European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa3921  0.346
2015 Smid D, Franssen F, Wilke S, Muris J, Rohde G, Jones P, Wouters E, Spruit M. Characterization of patients with COPD GOLD stage I and II referred for pulmonary rehabilitation European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa3696  0.382
2015 Wilke S, Bals R, Franssen F, Karch A, Koch A, Schulz H, Spruit M, Welte T, Wouters E, Jörres R, Vogelmeier C, Watz H. Impact of peripheral artery disease on functional capacity in patients with COPD: Results of the COSYCONET study European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa2069  0.452
2015 Vanfleteren M, Spruit M, Franssen F, Wouters E, Groenen M, Vanfleteren L. Differential response between cycling and walking test following pulmonary rehabilitation in patients with COPD depends on degree of lung hyperinflation European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Oa1758  0.382
2015 Magnussen H, Chanez P, Dahl R, Decramer M, Disse B, Finnigan H, Kirsten A, Rodriguez-Roisin R, Tetzlaff K, Towse L, Watz H, Wouters E, Calverley P. The impact of stepwise withdrawal of inhaled corticosteroids on exacerbations in COPD patients receiving dual bronchodilation: WISDOM study Pneumologie. 69: 67. DOI: 10.1055/S-0035-1544631  0.433
2014 Nakken N, Janssen DJ, van den Bogaart EH, Vercoulen JH, Wouters EF, Spruit MA. An observational, longitudinal study on the home environment of people with chronic obstructive pulmonary disease: the research protocol of the Home Sweet Home study. Bmj Open. 4: e006098. PMID 25384686 DOI: 10.1136/Bmjopen-2014-006098  0.478
2014 Watz H, Pitta F, Rochester CL, Garcia-Aymerich J, ZuWallack R, Troosters T, Vaes AW, Puhan MA, Jehn M, Polkey MI, Vogiatzis I, Clini EM, Toth M, Gimeno-Santos E, Waschki B, ... ... Wouters EF, et al. An official European Respiratory Society statement on physical activity in COPD. The European Respiratory Journal. 44: 1521-37. PMID 25359358 DOI: 10.1183/09031936.00046814  0.367
2014 Magnussen H, Disse B, Rodriguez-Roisin R, Kirsten A, Watz H, Tetzlaff K, Towse L, Finnigan H, Dahl R, Decramer M, Chanez P, Wouters EF, Calverley PM. Withdrawal of inhaled glucocorticoids and exacerbations of COPD. The New England Journal of Medicine. 371: 1285-94. PMID 25196117 DOI: 10.1056/NEJMoa1407154  0.361
2014 Sillen MJ, Franssen FM, Vaes AW, Delbressine JM, Wouters EF, Spruit MA. Metabolic load during strength training or NMES in individuals with COPD: results from the DICES trial. Bmc Pulmonary Medicine. 14: 146. PMID 25182377 DOI: 10.1186/1471-2466-14-146  0.306
2014 Janssen DJ, Müllerova H, Agusti A, Yates JC, Tal-Singer R, Rennard SI, Vestbo J, Wouters EF. Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort. Respiratory Medicine. 108: 1647-54. PMID 25135745 DOI: 10.1016/J.Rmed.2014.07.013  0.392
2014 Diaz AA, Zhou L, Young TP, McDonald ML, Harmouche R, Ross JC, San Jose Estepar R, Wouters EF, Coxson HO, MacNee W, Rennard S, Maltais F, Kinney GL, Hokanson JE, Washko GR, et al. Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers. Academic Radiology. 21: 1255-61. PMID 25088837 DOI: 10.1016/J.Acra.2014.05.013  0.339
2014 Vaes AW, Garcia-Aymerich J, Marott JL, Benet M, Groenen MT, Schnohr P, Franssen FM, Vestbo J, Wouters EF, Lange P, Spruit MA. Changes in physical activity and all-cause mortality in COPD. The European Respiratory Journal. 44: 1199-209. PMID 25063247 DOI: 10.1183/09031936.00023214  0.337
2014 Breyer MK, Spruit MA, Hanson CK, Franssen FM, Vanfleteren LE, Groenen MT, Bruijnzeel PL, Wouters EF, Rutten EP. Prevalence of metabolic syndrome in COPD patients and its consequences. Plos One. 9: e98013. PMID 24950070 DOI: 10.1371/Journal.Pone.0098013  0.34
2014 McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, ... ... Wouters EF, et al. Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 51: 678-87. PMID 24825563 DOI: 10.1165/Rcmb.2014-0135Oc  0.371
2014 Cleutjens FA, Janssen DJ, Ponds RW, Dijkstra JB, Wouters EF. COgnitive-pulmonary disease. Biomed Research International. 2014: 697825. PMID 24738069 DOI: 10.1155/2014/697825  0.341
2014 Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V, Cazzola M, Dall'Armi V, Daraselia N, Ros LD, Bufalo AD, ... ... Wouters EF, et al. A systems medicine clinical platform for understanding and managing non- communicable diseases. Current Pharmaceutical Design. 20: 5945-56. PMID 24641232 DOI: 10.2174/1381612820666140314130449  0.31
2014 Cleutjens FA, Wouters EF, Dijkstra JB, Spruit MA, Franssen FM, Vanfleteren LE, Ponds RW, Janssen DJ. The COgnitive-Pulmonary Disease (COgnitive-PD) study: protocol of a longitudinal observational comparative study on neuropsychological functioning of patients with COPD. Bmj Open. 4: e004495. PMID 24589828 DOI: 10.1136/Bmjopen-2013-004495  0.357
2014 McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, et al. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Annals of the American Thoracic Society. 11: 326-34. PMID 24558953 DOI: 10.1513/Annalsats.201307-229Oc  0.351
2014 Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, et al. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. American Journal of Respiratory and Critical Care Medicine. 189: 1022-30. PMID 24552242 DOI: 10.1164/Rccm.201311-2006Pp  0.448
2014 Cleutjens FA, Spruit MA, Ponds RW, Dijkstra JB, Franssen FM, Wouters EF, Janssen DJ. Cognitive functioning in obstructive lung disease: results from the United Kingdom biobank. Journal of the American Medical Directors Association. 15: 214-9. PMID 24513227 DOI: 10.1016/J.Jamda.2013.12.007  0.305
2014 Williams MC, Murchison JT, Edwards LD, Agustí A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Vestbo J, ... Wouters E, et al. Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality. Thorax. 69: 718-23. PMID 24473329 DOI: 10.1136/Thoraxjnl-2012-203151  0.342
2014 Sillen MJ, Franssen FM, Delbressine JM, Vaes AW, Wouters EF, Spruit MA. Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: results from the DICES trial. Thorax. 69: 525-31. PMID 24399630 DOI: 10.1136/Thoraxjnl-2013-204388  0.337
2014 Houben CH, Spruit MA, Wouters EF, Janssen DJ. A randomised controlled trial on the efficacy of advance care planning on the quality of end-of-life care and communication in patients with COPD: the research protocol. Bmj Open. 4: e004465. PMID 24384905 DOI: 10.1136/Bmjopen-2013-004465  0.416
2014 Spruit MA, Pitta F, Garvey C, ZuWallack RL, Roberts CM, Collins EG, Goldstein R, McNamara R, Surpas P, Atsuyoshi K, López-Campos JL, Vogiatzis I, Williams JE, Lareau S, Brooks D, ... ... Wouters EF, et al. Differences in content and organisational aspects of pulmonary rehabilitation programmes. The European Respiratory Journal. 43: 1326-37. PMID 24337043 DOI: 10.1183/09031936.00145613  0.424
2014 Janssen DJ, Schols JM, Wouters EF, Spruit MA. One-year stability of care dependency in patients with advanced chronic organ failure. Journal of the American Medical Directors Association. 15: 127-32. PMID 24314701 DOI: 10.1016/J.Jamda.2013.10.002  0.401
2014 Faner R, Tal-Singer R, Riley JH, Celli B, Vestbo J, MacNee W, Bakke P, Calverley PM, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, Miller BE, Rennard SI, ... Wouters EF, et al. Lessons from ECLIPSE: a review of COPD biomarkers. Thorax. 69: 666-72. PMID 24310110 DOI: 10.1136/Thoraxjnl-2013-204778  0.407
2014 Meis JJ, Bosma CB, Spruit MA, Franssen FM, Janssen DJ, Teixeira PJ, Augustin IM, Wouters EF, de Vries NK, Schols AM, Kremers SP. A qualitative assessment of COPD patients' experiences of pulmonary rehabilitation and guidance by healthcare professionals. Respiratory Medicine. 108: 500-10. PMID 24280544 DOI: 10.1016/J.Rmed.2013.11.001  0.418
2014 Cleutjens FA, Janssen DJ, Gijsen C, Dijkstra JB, Ponds RW, Wouters EF. [Cognitive impairment in patients with COPD: a review]. Tijdschrift Voor Gerontologie En Geriatrie. 45: 1-9. PMID 24254988 DOI: 10.1007/S12439-013-0053-1  0.376
2014 Ubags ND, Vernooy JH, Burg E, Hayes C, Bement J, Dilli E, Zabeau L, Abraham E, Poch KR, Nick JA, Dienz O, Zuñiga J, Wargo MJ, Mizgerd JP, Tavernier J, ... ... Wouters EF, et al. The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. Critical Care Medicine. 42: e143-51. PMID 24231757 DOI: 10.1097/Ccm.0000000000000048  0.331
2014 Andrianopoulos V, Franssen FM, Peeters JP, Ubachs TJ, Bukari H, Groenen M, Burtin C, Vogiatzis I, Wouters EF, Spruit MA. Exercise-induced oxygen desaturation in COPD patients without resting hypoxemia. Respiratory Physiology & Neurobiology. 190: 40-6. PMID 24121092 DOI: 10.1016/J.Resp.2013.10.002  0.4
2014 Hilmarsen CW, Wilke S, Engan H, Spruit MA, Rodenburg J, Janssen DJ, Steinshamn S, Jones PW, Wouters EF, Oldervoll L, Franssen FM. Impact of symptoms of anxiety and depression on COPD Assessment Test scores. The European Respiratory Journal. 43: 898-900. PMID 24114965 DOI: 10.1183/09031936.00163913  0.407
2014 Vanfleteren LE, Kocks JW, Stone IS, Breyer-Kohansal R, Greulich T, Lacedonia D, Buhl R, Fabbri LM, Pavord ID, Barnes N, Wouters EF, Agusti A. Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms? Thorax. 69: 72-9. PMID 23794191 DOI: 10.1136/Thoraxjnl-2013-203602  0.391
2014 Magnussen H, Disse B, Rodriguez-Roisin R, Kirsten A, Watz H, Tetzlaff K, Towse L, Finnigan H, Dahl R, Decramer M, Chanez P, Wouters E, Calverley P. The Impact of Stepwise Withdrawal of ICS on FEV1, mMRC, and SQRQ in Severe to Very Severe COPD Patients Treated With LAMA+LABA: The WISDOM Study Chest. 146. DOI: 10.1378/Chest.1994402  0.358
2014 Magnussen H, Disse B, Rodriguez-Roisin R, Kirsten A, Watz H, Tetzlaff K, Towse L, Finnigan H, Dahl R, Decramer M, Chanez P, Wouters E, Calverley P. Exacerbation Risk Is Not Worse When ICS Are Withdrawn in a Stepwise Manner in Severe to Very Severe COPD Patients Receiving LAMA+LABA: The WISDOM Study Chest. 146. DOI: 10.1378/Chest.1994339  0.347
2014 Yohannes A, Mülerova H, Li H, Hanania N, Lavoie K, Tal-Singer R, Vestbo J, Wouters E. Persistence of Depressive Symptoms in Patients With COPD: A 3-Year Longitudinal Follow-up Analysis of the ECLIPSE Study Cohort Chest. 146. DOI: 10.1378/Chest.1978679  0.319
2014 Rabinovich RA, Miller BE, Wrobel K, Choudhury G, Ranjit K, Drost EM, Edwards LD, Lomas DA, Rennard SI, Agusti A, Tal-Singer R, Vestbo J, Wouters E, Beek EV, Murchison JT, et al. S51 Circulating Desmosine Relates To Cardiovascular Comorbidity, Coronary Artery Calcification Score (cacs), Systemic Inflammation And Mortality In Patients With Copd Thorax. 69: A28-A29. DOI: 10.1136/Thoraxjnl-2014-206260.57  0.384
2014 Joppa P, Franssen F, Tkacova R, Hanson C, Rennard S, Silverman E, McDonald M, Calverley P, Wouters E, Rutten E. OP011: The Combination of Low Fat-Free Mass and High Fat Mass is Related to Functional Outcome and Systemic Inflammation in Patients with COPD Clinical Nutrition. 33: S5. DOI: 10.1016/S0261-5614(14)50011-8  0.305
2013 Romme EA, McAllister DA, Murchison JT, Van Beek EJ, Petrides GS, Price CO, Rutten EP, Smeenk FW, Wouters EF, MacNee W. Associations between COPD related manifestations: a cross-sectional study. Respiratory Research. 14: 129. PMID 24251912 DOI: 10.1186/1465-9921-14-129  0.341
2013 Rutten EP, Calverley PM, Casaburi R, Agusti A, Bakke P, Celli B, Coxson HO, Crim C, Lomas DA, Macnee W, Miller BE, Rennard SI, Scanlon PD, Silverman EK, Tal-Singer R, ... ... Wouters EF, et al. Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes? Annals of Nutrition & Metabolism. 63: 239-47. PMID 24216978 DOI: 10.1159/000353211  0.454
2013 Agustí A, Barberà JA, Wouters EF, Peinado VI, Jeffery PK. Lungs, bone marrow, and adipose tissue. A network approach to the pathobiology of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 1396-406. PMID 24175885 DOI: 10.1164/Rccm.201308-1404Pp  0.4
2013 Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, Hill K, Holland AE, Lareau SC, Man WD, Pitta F, Sewell L, Raskin J, Bourbeau J, Crouch R, ... ... Wouters EF, et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. American Journal of Respiratory and Critical Care Medicine. 188: e13-64. PMID 24127811 DOI: 10.1164/Rccm.201309-1634St  0.449
2013 Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustí A, Fabbri LM, et al. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 948-57. PMID 23947473 DOI: 10.1164/Rccm.201302-0247Oc  0.435
2013 Miller J, Edwards LD, Agustí A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Vestbo J, Wouters E, et al. Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. Respiratory Medicine. 107: 1376-84. PMID 23791463 DOI: 10.1016/J.Rmed.2013.05.001  0.349
2013 Agusti A, Edwards LD, Celli B, Macnee W, Calverley PM, Müllerova H, Lomas DA, Wouters E, Bakke P, Rennard S, Crim C, Miller BE, Coxson HO, Yates JC, Tal-Singer R, et al. Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort. The European Respiratory Journal. 42: 636-46. PMID 23766334 DOI: 10.1183/09031936.00195212  0.373
2013 Stoilkova A, Wouters EF, Spruit MA, Franssen FM, Janssen DJ. The relationship between coping styles and clinical outcomes in patients with COPD entering pulmonary rehabilitation. Copd. 10: 316-23. PMID 23713594 DOI: 10.3109/15412555.2012.744389  0.421
2013 Sillen MJ, Franssen FM, Delbressine JM, Uszko-Lencer NH, Vanfleteren LE, Rutten EP, Wouters EF, Spruit MA. Heterogeneity in clinical characteristics and co-morbidities in dyspneic individuals with COPD GOLD D: findings of the DICES trial. Respiratory Medicine. 107: 1186-94. PMID 23706780 DOI: 10.1016/J.Rmed.2013.04.020  0.434
2013 Hanson C, Rutten EP, Wouters EF, Rennard S. Diet and vitamin D as risk factors for lung impairment and COPD. Translational Research : the Journal of Laboratory and Clinical Medicine. 162: 219-36. PMID 23685188 DOI: 10.1016/J.Trsl.2013.04.004  0.379
2013 Mesquita R, Janssen DJ, Wouters EF, Schols JM, Pitta F, Spruit MA. Within-day test-retest reliability of the Timed Up & Go test in patients with advanced chronic organ failure. Archives of Physical Medicine and Rehabilitation. 94: 2131-8. PMID 23583345 DOI: 10.1016/J.Apmr.2013.03.024  0.369
2013 Janssen DJ, Spruit MA, Schols JM, Wouters EF. Dynamic preferences for site of death among patients with advanced chronic obstructive pulmonary disease, chronic heart failure, or chronic renal failure. Journal of Pain and Symptom Management. 46: 826-36. PMID 23571204 DOI: 10.1016/J.Jpainsymman.2013.01.007  0.361
2013 Stoilkova A, Janssen DJ, Franssen FM, Spruit MA, Wouters EF. Coping styles in patients with COPD before and after pulmonary rehabilitation. Respiratory Medicine. 107: 825-33. PMID 23541485 DOI: 10.1016/J.Rmed.2013.03.001  0.438
2013 Romme EA, Murchison JT, Edwards LD, van Beek E, Murchison DM, Rutten EP, Smeenk FW, Williams MC, Wouters EF, MacNee W. CT-measured bone attenuation in patients with chronic obstructive pulmonary disease: relation to clinical features and outcomes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1369-77. PMID 23361992 DOI: 10.1002/Jbmr.1873  0.335
2013 Sillen MJ, Vercoulen JH, van 't Hul AJ, Klijn PH, Wouters EF, van Ranst D, Peters JB, van Keimpema AR, Franssen FM, Otten HJ, Molema J, Jansen JJ, Spruit MA. The use of regression equations to estimate peak work rate in people with COPD -reply from the authors. Copd. 10: 120-1. PMID 23272669 DOI: 10.3109/15412555.2012.736310  0.331
2013 Polkey MI, Spruit MA, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agustí A, Bakke PS, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, ... ... Wouters EF, et al. Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. American Journal of Respiratory and Critical Care Medicine. 187: 382-6. PMID 23262518 DOI: 10.1164/Rccm.201209-1596Oc  0.424
2013 Janssen DJ, Wouters EF, Schols JM, Spruit MA. Care dependency independently predicts two-year survival in outpatients with advanced chronic organ failure. Journal of the American Medical Directors Association. 14: 194-8. PMID 23141207 DOI: 10.1016/J.Jamda.2012.09.022  0.316
2013 Rutten E, Lenaerts K, Buurman W, Wouters E. Pp124-Mon Disturbed Intestinal Integrity In Copd Patients; Effects Of Activities Of Daily Living Clinical Nutrition. 32. DOI: 10.1016/S0261-5614(13)60435-5  0.365
2012 Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustí A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, et al. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 186: 1238-47. PMID 23144326 DOI: 10.1164/Rccm.201206-1013Oc  0.412
2012 Vanspauwen MJ, Franssen FM, Raoult D, Wouters EF, Bruggeman CA, Linssen CF. Infections with mimivirus in patients with chronic obstructive pulmonary disease. Respiratory Medicine. 106: 1690-4. PMID 22990040 DOI: 10.1016/J.Rmed.2012.08.019  0.419
2012 Al-shair K, Muellerova H, Yorke J, Rennard SI, Wouters EF, Hanania NA, Sharafkhaneh A, Vestbo J. Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale. Health and Quality of Life Outcomes. 10: 100. PMID 22913289 DOI: 10.1186/1477-7525-10-100  0.311
2012 Wilke S, Janssen DJ, Wouters EF, Schols JM, Franssen FM, Spruit MA. Correlations between disease-specific and generic health status questionnaires in patients with advanced COPD: a one-year observational study. Health and Quality of Life Outcomes. 10: 98. PMID 22909154 DOI: 10.1186/1477-7525-10-98  0.365
2012 Vaes AW, Franssen FM, Meijer K, Cuijpers MW, Wouters EF, Rutten EP, Spruit MA. Effects of body mass index on task-related oxygen uptake and dyspnea during activities of daily life in COPD. Plos One. 7: e41078. PMID 22815922 DOI: 10.1371/Journal.Pone.0041078  0.361
2012 Breyer MK, Rutten EP, Locantore NW, Watkins ML, Miller BE, Wouters EF. Dysregulated adipokine metabolism in chronic obstructive pulmonary disease. European Journal of Clinical Investigation. 42: 983-91. PMID 22703238 DOI: 10.1111/J.1365-2362.2012.02686.X  0.406
2012 Albert P, Agusti A, Edwards L, Tal-Singer R, Yates J, Bakke P, Celli BR, Coxson HO, Crim C, Lomas DA, Macnee W, Miller B, Rennard S, Silverman EK, Vestbo J, ... Wouters E, et al. Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax. 67: 701-8. PMID 22696176 DOI: 10.1136/Thoraxjnl-2011-201458  0.461
2012 Romme EA, Murchison JT, Phang KF, Jansen FH, Rutten EP, Wouters EF, Smeenk FW, Van Beek EJ, Macnee W. Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 2338-43. PMID 22692725 DOI: 10.1002/Jbmr.1678  0.377
2012 Engelen MP, De Castro CL, Rutten EP, Wouters EF, Schols AM, Deutz NE. Enhanced anabolic response to milk protein sip feeding in elderly subjects with COPD is associated with a reduced splanchnic extraction of multiple amino acids. Clinical Nutrition (Edinburgh, Scotland). 31: 616-24. PMID 22682082 DOI: 10.1016/J.Clnu.2012.04.006  0.35
2012 Agustí A, Edwards LD, Rennard SI, MacNee W, Tal-Singer R, Miller BE, Vestbo J, Lomas DA, Calverley PM, Wouters E, Crim C, Yates JC, Silverman EK, Coxson HO, Bakke P, et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. Plos One. 7: e37483. PMID 22624038 DOI: 10.1371/Journal.Pone.0037483  0.418
2012 Annegarn J, Spruit MA, Savelberg HH, Willems PJ, van de Bool C, Schols AM, Wouters EF, Meijer K. Differences in walking pattern during 6-min walk test between patients with COPD and healthy subjects. Plos One. 7: e37329. PMID 22624017 DOI: 10.1371/Journal.Pone.0037329  0.427
2012 Engelen MP, Rutten EP, De Castro CL, Wouters EF, Schols AM, Deutz NE. Casein protein results in higher prandial and exercise induced whole body protein anabolism than whey protein in chronic obstructive pulmonary disease. Metabolism: Clinical and Experimental. 61: 1289-300. PMID 22512824 DOI: 10.1016/J.Metabol.2012.03.001  0.329
2012 Janssen DJ, Spruit MA, Wouters EF, Schols JM. Symptom distress in advanced chronic organ failure: disagreement among patients and family caregivers. Journal of Palliative Medicine. 15: 447-56. PMID 22475192 DOI: 10.1089/Jpm.2011.0394  0.378
2012 Celli BR, Locantore N, Yates J, Tal-Singer R, Miller BE, Bakke P, Calverley P, Coxson H, Crim C, Edwards LD, Lomas DA, Duvoix A, MacNee W, Rennard S, Silverman E, ... ... Wouters E, et al. Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 185: 1065-72. PMID 22427534 DOI: 10.1164/Rccm.201110-1792Oc  0.377
2012 Waschki B, Spruit MA, Watz H, Albert PS, Shrikrishna D, Groenen M, Smith C, Man WD, Tal-Singer R, Edwards LD, Calverley PM, Magnussen H, Polkey MI, Wouters EF. Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study. Respiratory Medicine. 106: 522-30. PMID 22118987 DOI: 10.1016/J.Rmed.2011.10.022  0.316
2012 Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, ... ... Wouters E, et al. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Human Molecular Genetics. 21: 947-57. PMID 22080838 DOI: 10.1093/Hmg/Ddr524  0.33
2012 Janssen DJ, Spruit MA, Schols JM, Cox B, Nawrot TS, Curtis JR, Wouters EF. Predicting changes in preferences for life-sustaining treatment among patients with advanced chronic organ failure. Chest. 141: 1251-9. PMID 22016488 DOI: 10.1378/Chest.11-1472  0.354
2012 Spruit MA, Polkey MI, Celli B, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agusti A, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, ... ... Wouters EF, et al. Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. Journal of the American Medical Directors Association. 13: 291-7. PMID 21778120 DOI: 10.1016/J.Jamda.2011.06.009  0.452
2012 Janssen DJ, Spruit MA, Wouters EF, Schols JM. Family caregiving in advanced chronic organ failure. Journal of the American Medical Directors Association. 13: 394-9. PMID 21621478 DOI: 10.1016/J.Jamda.2011.04.017  0.351
2012 Annegarn J, Meijer K, Passos VL, Stute K, Wiechert J, Savelberg HH, Schols AM, Wouters EF, Spruit MA. Problematic activities of daily life are weakly associated with clinical characteristics in COPD. Journal of the American Medical Directors Association. 13: 284-90. PMID 21450242 DOI: 10.1016/J.Jamda.2011.01.002  0.462
2012 Janssen DJ, Engelberg RA, Wouters EF, Curtis JR. Advance care planning for patients with COPD: past, present and future. Patient Education and Counseling. 86: 19-24. PMID 21316899 DOI: 10.1016/J.Pec.2011.01.007  0.405
2011 Annegarn J, Spruit MA, Uszko-Lencer NH, Vanbelle S, Savelberg HH, Schols AM, Wouters EF, Meijer K. Objective physical activity assessment in patients with chronic organ failure: a validation study of a new single-unit activity monitor. Archives of Physical Medicine and Rehabilitation. 92: 1852-1857.e1. PMID 22032218 DOI: 10.1016/J.Apmr.2011.06.021  0.325
2011 Vestbo J, Edwards LD, Scanlon PD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, MacNee W, Miller BE, Silverman EK, Tal-Singer R, ... Wouters E, et al. Changes in forced expiratory volume in 1 second over time in COPD. The New England Journal of Medicine. 365: 1184-92. PMID 21991892 DOI: 10.1056/Nejmoa1105482  0.419
2011 Vogelmeier CF, Wouters EF. Treating the systemic effects of chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 8: 376-9. PMID 21816995 DOI: 10.1513/pats.201102-020RM  0.352
2011 Rutten EP, Grydeland TB, Pillai SG, Wagers S, Dirksen A, Coxson HO, Gulsvik A, Wouters EF, Bakke PS. Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD. Pulmonary Medicine. 2011: 419328. PMID 21647214 DOI: 10.1155/2011/419328  0.351
2011 Janssen DJ, Spruit MA, Uszko-Lencer NH, Schols JM, Wouters EF. Symptoms, comorbidities, and health care in advanced chronic obstructive pulmonary disease or chronic heart failure. Journal of Palliative Medicine. 14: 735-43. PMID 21510771 DOI: 10.1089/Jpm.2010.0479  0.404
2011 Crim C, Celli B, Edwards LD, Wouters E, Coxson HO, Tal-Singer R, Calverley PMA. Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results Respiratory Medicine. 105: 1069-1078. PMID 21481577 DOI: 10.1016/J.Rmed.2011.01.010  0.407
2011 Janssen DJ, Franssen FM, Wouters EF, Schols JM, Spruit MA. Impaired health status and care dependency in patients with advanced COPD or chronic heart failure. Quality of Life Research : An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. 20: 1679-88. PMID 21442430 DOI: 10.1007/S11136-011-9892-9  0.404
2011 Vaes AW, Wouters EF, Franssen FM, Uszko-Lencer NH, Stakenborg KH, Westra M, Meijer K, Schols AM, Janssen PP, Spruit MA. Task-related oxygen uptake during domestic activities of daily life in patients with COPD and healthy elderly subjects. Chest. 140: 970-9. PMID 21415128 DOI: 10.1378/Chest.10-3005  0.414
2011 Janssen DJ, Curtis JR, Au DH, Spruit MA, Downey L, Schols JM, Wouters EF, Engelberg RA. Patient-clinician communication about end-of-life care for Dutch and US patients with COPD. The European Respiratory Journal. 38: 268-76. PMID 21233263 DOI: 10.1183/09031936.00157710  0.344
2011 Spruit MA, Wouters EF, Eterman RM, Meijer K, Wagers SS, Stakenborg KH, Uszko-Lencer NH. Task-related oxygen uptake and symptoms during activities of daily life in CHF patients and healthy subjects. European Journal of Applied Physiology. 111: 1679-86. PMID 21210281 DOI: 10.1007/S00421-010-1794-Y  0.335
2011 Sillen MJ, Wouters EF, Franssen FM, Meijer K, Stakenborg KH, Spruit MA. Oxygen uptake, ventilation, and symptoms during low-frequency versus high-frequency NMES in COPD: a pilot study. Lung. 189: 21-6. PMID 21080183 DOI: 10.1007/S00408-010-9265-0  0.362
2011 Wan ES, Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Won S, Lange C, Pillai SG, Anderson WH, Kong X, Lomas DA, Bakke PS, Gulsvik A, Regan EA, ... ... Wouters EF, et al. Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 45: 304-10. PMID 21037115 DOI: 10.1165/Rcmb.2010-0294Oc  0.319
2011 Hanania NA, Müllerova H, Locantore NW, Vestbo J, Watkins ML, Wouters EF, Rennard SI, Sharafkhaneh A. Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort. American Journal of Respiratory and Critical Care Medicine. 183: 604-11. PMID 20889909 DOI: 10.1164/Rccm.201003-0472Oc  0.442
2011 Janssen DJ, Spruit MA, Schols JM, Wouters EF. A call for high-quality advance care planning in outpatients with severe COPD or chronic heart failure. Chest. 139: 1081-8. PMID 20829337 DOI: 10.1378/Chest.10-1753  0.355
2011 Bakke PS, Zhu G, Gulsvik A, Kong X, Agusti AG, Calverley PM, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EF, Anderson W, Lomas DA, et al. Candidate genes for COPD in two large data sets. The European Respiratory Journal. 37: 255-63. PMID 20562129 DOI: 10.1183/09031936.00091709  0.347
2010 Hernandes NA, Wouters EF, Meijer K, Annegarn J, Pitta F, Spruit MA. Reproducibility of 6-minute walking test in patients with COPD. The European Respiratory Journal. 38: 261-7. PMID 21177838 DOI: 10.1183/09031936.00142010  0.351
2010 Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA. Susceptibility to exacerbation in chronic obstructive pulmonary disease. The New England Journal of Medicine. 363: 1128-38. PMID 20843247 DOI: 10.1056/Nejmoa0909883  0.455
2010 Agusti A, Calverley PM, Celli B, Coxson HO, Edwards LD, Lomas DA, MacNee W, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Wouters E, Yates JC, Vestbo J. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respiratory Research. 11: 122. PMID 20831787 DOI: 10.1186/1465-9921-11-122  0.451
2010 Janssen DJ, Spruit MA, Leue C, Gijsen C, Hameleers H, Schols JM, Wouters EF. Symptoms of anxiety and depression in COPD patients entering pulmonary rehabilitation. Chronic Respiratory Disease. 7: 147-57. PMID 20688892 DOI: 10.1177/1479972310369285  0.372
2010 Sørheim IC, Bakke P, Gulsvik A, Pillai SG, Johannessen A, Gaarder PI, Campbell EJ, Agustí A, Calverley PM, Donner CF, Make BJ, Rennard SI, Vestbo J, Wouters EF, Paré PD, et al. α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest. 138: 1125-32. PMID 20595457 DOI: 10.1378/Chest.10-0746  0.303
2010 Janssen DJ, Spruit MA, Alsemgeest TP, Does JD, Schols JM, Wouters EF. A patient-centred interdisciplinary palliative care programme for end-stage chronic respiratory diseases. International Journal of Palliative Nursing. 16: 189-94. PMID 20559181 DOI: 10.12968/Ijpn.2010.16.4.47785  0.404
2010 Vernooy JH, Bracke KR, Drummen NE, Pauwels NS, Zabeau L, van Suylen RJ, Tavernier J, Joos GF, Wouters EF, Brusselle GG. Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 7169-77. PMID 20488786 DOI: 10.4049/Jimmunol.0900963  0.314
2010 Spruit MA, Watkins ML, Edwards LD, Vestbo J, Calverley PM, Pinto-Plata V, Celli BR, Tal-Singer R, Wouters EF. Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort. Respiratory Medicine. 104: 849-57. PMID 20471236 DOI: 10.1016/J.Rmed.2009.12.007  0.47
2010 Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, ... ... Wouters EF, et al. Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. American Journal of Respiratory and Critical Care Medicine. 182: 605-13. PMID 20463177 DOI: 10.1164/Rccm.200910-1586Oc  0.324
2010 Van Pottelberge GR, Bracke KR, Van den Broeck S, Reinartz SM, van Drunen CM, Wouters EF, Verleden GM, Vermassen FE, Joos GF, Brusselle GG. Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD. The European Respiratory Journal. 36: 781-91. PMID 20351031 DOI: 10.1183/09031936.00140409  0.431
2010 Koning CJM, Jonkers D, Smidt H, Rombouts F, Pennings HJ, Wouters E, Stobberingh E, Stockbrügger R. The effect of a multispecies probiotic on the composition of the faecal microbiota and bowel habits in chronic obstructive pulmonary disease patients treated with antibiotics British Journal of Nutrition. 103: 1452-1460. PMID 20021703 DOI: 10.1017/S0007114509993497  0.364
2010 Van Berkel JJ, Dallinga JW, Möller GM, Godschalk RW, Moonen EJ, Wouters EF, Van Schooten FJ. A profile of volatile organic compounds in breath discriminates COPD patients from controls. Respiratory Medicine. 104: 557-63. PMID 19906520 DOI: 10.1016/J.Rmed.2009.10.018  0.44
2010 Bracke KR, Dentener MA, Papakonstantinou E, Vernooy JH, Demoor T, Pauwels NS, Cleutjens J, van Suylen RJ, Joos GF, Brusselle GG, Wouters EF. Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice. American Journal of Respiratory Cell and Molecular Biology. 42: 753-61. PMID 19675307 DOI: 10.1165/Rcmb.2008-0424Oc  0.353
2009 Spruit MA, Janssen DJ, Franssen FM, Wouters EF. Rehabilitation and palliative care in lung fibrosis. Respirology (Carlton, Vic.). 14: 781-7. PMID 19703060 DOI: 10.1111/J.1440-1843.2009.01599.X  0.431
2009 Breyer MK, Spruit MA, Celis AP, Rutten EP, Janssen PP, Wouters EF. Highly elevated C-reactive protein levels in obese patients with COPD: a fat chance? Clinical Nutrition (Edinburgh, Scotland). 28: 642-7. PMID 19540024 DOI: 10.1016/J.Clnu.2009.05.005  0.421
2009 Sillen MJ, Speksnijder CM, Eterman RM, Janssen PP, Wagers SS, Wouters EF, Uszko-Lencer NH, Spruit MA. Effects of neuromuscular electrical stimulation of muscles of ambulation in patients with chronic heart failure or COPD: a systematic review of the English-language literature. Chest. 136: 44-61. PMID 19363213 DOI: 10.1378/Chest.08-2481  0.373
2009 Graat-Verboom L, Spruit MA, van den Borne BE, Smeenk FW, Martens EJ, Lunde R, Wouters EF. Correlates of osteoporosis in chronic obstructive pulmonary disease: An underestimated systemic component. Respiratory Medicine. 103: 1143-51. PMID 19304474 DOI: 10.1016/J.Rmed.2009.02.014  0.441
2009 Schermer TRJ, Chavannes N, Dekhuijzen R, Wouters E, Muris J, Akkermans R, Schayck Ov, Weel Cv. Fluticasone and N-acetylcysteine in primary care patients with COPD or chronic bronchitis Respiratory Medicine. 103: 542-551. PMID 19138505 DOI: 10.1016/J.Rmed.2008.11.003  0.403
2009 Pitta F, Breyer MK, Hernandes NA, Teixeira D, Sant'Anna TJ, Fontana AD, Probst VS, Brunetto AF, Spruit MA, Wouters EF, Burghuber OC, Hartl S. Comparison of daily physical activity between COPD patients from Central Europe and South America. Respiratory Medicine. 103: 421-6. PMID 19006659 DOI: 10.1016/J.Rmed.2008.09.019  0.399
2009 Gosker HR, Langen RC, Bracke KR, Joos GF, Brusselle GG, Steele C, Ward KA, Wouters EF, Schols AM. Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure. American Journal of Respiratory Cell and Molecular Biology. 40: 710-6. PMID 18988919 DOI: 10.1165/Rcmb.2008-0312Oc  0.387
2009 Vernooy JH, Drummen NE, van Suylen RJ, Cloots RH, Möller GM, Bracke KR, Zuyderduyn S, Dentener MA, Brusselle GG, Hiemstra PS, Wouters EF. Enhanced pulmonary leptin expression in patients with severe COPD and asymptomatic smokers. Thorax. 64: 26-32. PMID 18835960 DOI: 10.1136/Thx.2007.085423  0.453
2008 Janssen DJ, Alsemgeest TP, Widdershoven GA, Wouters EF, Schols JM, Spruit MA. The last wish of a patient with end stage chronic obstructive pulmonary disease. Bmj (Clinical Research Ed.). 337: a2701. PMID 19064602 DOI: 10.1136/Bmj.A2701  0.435
2008 Houben JM, Mercken EM, Ketelslegers HB, Bast A, Wouters EF, Hageman GJ, Schols AM. Telomere shortening in chronic obstructive pulmonary disease. Respiratory Medicine. 103: 230-6. PMID 18945604 DOI: 10.1016/j.rmed.2008.09.003  0.354
2008 Janssen DJ, Spruit MA, Wouters EF, Schols JM. Daily symptom burden in end-stage chronic organ failure: a systematic review. Palliative Medicine. 22: 938-48. PMID 18801874 DOI: 10.1177/0269216308096906  0.409
2008 Decramer M, Rennard S, Troosters T, Mapel DW, Giardino N, Mannino D, Wouters E, Sethi S, Cooper CB. COPD as a lung disease with systemic consequences--clinical impact, mechanisms, and potential for early intervention. Copd. 5: 235-56. PMID 18671149 DOI: 10.1080/15412550802237531  0.445
2008 Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, et al. Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 178: 500-5. PMID 18565956 DOI: 10.1164/Rccm.200801-059Oc  0.425
2008 Janssen DJ, Wouters EF, Schols JM, Spruit MA. Self-perceived symptoms and care needs of patients with severe to very severe chronic obstructive pulmonary disease, congestive heart failure or chronic renal failure and its consequences for their closest relatives: the research protocol. Bmc Palliative Care. 7: 5. PMID 18460203 DOI: 10.1186/1472-684X-7-5  0.419
2008 Spruit MA, Pennings HJ, Does JD, Möller GM, Janssen PP, Wouters EF. Serum LDH and exercise capacity in COPD. Thorax. 63: 472. PMID 18443166 DOI: 10.1136/Thx.2007.086363  0.375
2008 Cazzola M, MacNee W, Martinez FJ, Rabe KF, Franciosi LG, Barnes PJ, Brusasco V, Burge PS, Calverley PM, Celli BR, Jones PW, Mahler DA, Make B, Miravitlles M, Page CP, ... ... Wouters EF, et al. Outcomes for COPD pharmacological trials: from lung function to biomarkers. The European Respiratory Journal. 31: 416-69. PMID 18238951 DOI: 10.1183/09031936.00099306  0.368
2008 Derom E, Weel Cv, Liistro G, Buffels J, Schermer T, Lammers E, Wouters E, Decramer M. Primary care spirometry. European Respiratory Journal. 31: 197-203. PMID 18166597 DOI: 10.1183/09031936.00066607  0.395
2008 Koning C, Jonkers D, Tijsseling L, Pennings H, Wouters E, Stobberingh E, Stockbrugger R. W1386 The Effect of a Multispecies Probiotic On the Composition of the Fecal Microbiota and Bowel Habits in COPD Patients Treated with Antibiotics Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63236-9  0.333
2008 Koning C, Jonkers D, Smidt H, Pennings H, Wouters E, Stobberingh E, Stockbrugger R. W1385 The Composition of the Dominant Fecal Microbiota in COPD Patients Receiving Multispecies Probiotics During and After Antibiotic Intake Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63235-7  0.328
2007 Engelen MP, Rutten EP, De Castro CL, Wouters EF, Schols AM, Deutz NE. Supplementation of soy protein with branched-chain amino acids alters protein metabolism in healthy elderly and even more in patients with chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition. 85: 431-9. PMID 17284740 DOI: 10.1093/Ajcn/85.2.431  0.403
2007 Vernooy JH, Möller GM, van Suylen RJ, van Spijk MP, Cloots RH, Hoet PH, Pennings HJ, Wouters EF. Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 175: 464-72. PMID 17138956 DOI: 10.1164/Rccm.200602-169Oc  0.445
2007 Bolton CE, Broekhuizen R, Ionescu AA, Nixon LS, Wouters EF, Shale DJ, Schols AM. Cellular protein breakdown and systemic inflammation are unaffected by pulmonary rehabilitation in COPD. Thorax. 62: 109-14. PMID 16928709 DOI: 10.1136/Thx.2006.060368  0.453
2006 Nici L, ZuWallack R, Wouters E, Donner CF. On pulmonary rehabilitation and the flight of the bumblebee: the ATS/ERS Statement on Pulmonary Rehabilitation European Respiratory Journal. 28: 461-462. PMID 16946088 DOI: 10.1183/09031936.06.00075106  0.472
2006 Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, Carone M, Celli B, Engelen M, Fahy B, Garvey C, Goldstein R, Gosselink R, Lareau S, MacIntyre N, et al. American thoracic society/European respiratory society statement on pulmonary rehabilitation American Journal of Respiratory and Critical Care Medicine. 173: 1390-1413. PMID 16760357 DOI: 10.1164/Rccm.200508-1211St  0.36
2006 Dentener M, Louis R, Cloots R, Henket M, Wouters E. Differences in local versus systemic TNFalpha production in COPD: inhibitory effect of hyaluronan on LPS induced blood cell TNFalpha release. Thorax. 61: 478-484. PMID 16517575 DOI: 10.1136/Thx.2005.053330  0.341
2005 Celli BR, Calverley PM, Rennard SI, Wouters EF, Agusti A, Anthonisen N, Macnee W, Jones P, Pride N, Rodriguez-Roisin R, Rossi A, Wanner A. Proposal for a multidimensional staging system for chronic obstructive pulmonary disease. Respiratory Medicine. 99: 1546-54. PMID 16291077 DOI: 10.1016/J.Rmed.2005.03.019  0.442
2005 Rutten EP, Engelen MP, Castro CL, Wouters EF, Schols AM, Deutz NE. Decreased whole-body and splanchnic glutamate metabolism in healthy elderly men and patients with chronic obstructive pulmonary disease in the postabsorptive state and in response to feeding. The Journal of Nutrition. 135: 2166-70. PMID 16140893 DOI: 10.1093/Jn/135.9.2166  0.358
2005 Wouters EF. Local and systemic inflammation in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 2: 26-33. PMID 16113466 DOI: 10.1513/pats.200408-039MS  0.304
2005 Engelen MP, Rutten EP, De Castro CL, Wouters EF, Schols AM, Deutz NE. Altered interorgan response to feeding in patients with chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition. 82: 366-72. PMID 16087980 DOI: 10.1093/Ajcn.82.2.366  0.474
2005 Schols AM, Broekhuizen R, Weling-Scheepers CA, Wouters EF. Body composition and mortality in chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition. 82: 53-9. PMID 16002800 DOI: 10.1093/ajcn.82.1.53  0.344
2005 Wouters E, Postma D, Fokkens B, Hop W, Prins J, Kuipers A, Pasma H, Hensing CAJ, Creutzberg E. Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a randomised controlled trial Thorax. 60: 480-487. PMID 15923248 DOI: 10.1136/Thx.2004.034280  0.412
2005 Reynaert NL, Ckless K, Wouters EF, van der Vliet A, Janssen-Heininger YM. Nitric oxide and redox signaling in allergic airway inflammation. Antioxidants & Redox Signaling. 7: 129-43. PMID 15650402 DOI: 10.1089/Ars.2005.7.129  0.318
2004 Reid J, Price D, van der Molen T, Housset B, Jardim J, Jones P, Kardos P, Muir JF, Paggiaro P, Rennard S, Wouters E. Development of a primary-care tool to assess treatment success in COPD: consensus report from a closed meeting of respiratory and primary-care specialists. Primary Care Respiratory Journal : Journal of the General Practice Airways Group. 13: 99-104. PMID 16701649 DOI: 10.1016/J.Pcrj.2004.03.002  0.408
2004 Wagena EJ, Kant I, van Amelsvoort LG, Wouters EF, van Schayck CP, Swaen GM. Risk of depression and anxiety in employees with chronic bronchitis: the modifying effect of cigarette smoking. Psychosomatic Medicine. 66: 729-34. PMID 15385698 DOI: 10.1097/01.Psy.0000138127.00991.Cf  0.32
2004 Wagena EJ, Kant I, Huibers MJ, van Amelsvoort LG, Swaen GM, Wouters EF, van Schayck CP. Psychological distress and depressed mood in employees with asthma, chronic bronchitis or emphysema: a population-based observational study on prevalence and the relationship with smoking cigarettes. European Journal of Epidemiology. 19: 147-53. PMID 15080082 DOI: 10.1023/B:Ejep.0000017825.07470.41  0.336
2002 van der Pouw Kraan TC, Küçükaycan M, Bakker AM, Baggen JM, van der Zee JS, Dentener MA, Wouters EF, Verweij CL. Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism. Genes and Immunity. 3: 436-9. PMID 12424628 DOI: 10.1038/Sj.Gene.6363896  0.381
2002 Vernooy JH, Küçükaycan M, Jacobs JA, Chavannes NH, Buurman WA, Dentener MA, Wouters EF. Local and systemic inflammation in patients with chronic obstructive pulmonary disease: soluble tumor necrosis factor receptors are increased in sputum. American Journal of Respiratory and Critical Care Medicine. 166: 1218-24. PMID 12403691 DOI: 10.1164/rccm.2202023  0.301
2002 Langendijk JA, Aaronson NK, de Jong JM, ten Velde GP, Muller MJ, Slotman BJ, Wouters EF. Quality of life after curative radiotherapy in Stage I non-small-cell lung cancer. International Journal of Radiation Oncology, Biology, Physics. 53: 847-53. PMID 12095549 DOI: 10.1016/S0360-3016(02)02847-X  0.522
2002 Gosker HR, Engelen MP, van Mameren H, van Dijk PJ, van der Vusse GJ, Wouters EF, Schols AM. Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition. 76: 113-9. PMID 12081824 DOI: 10.1093/Ajcn/76.1.113  0.329
2002 Gosker HR, van Mameren H, van Dijk PJ, Engelen MP, van der Vusse GJ, Wouters EF, Schols AM. Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease. The European Respiratory Journal. 19: 617-25. PMID 11998989 DOI: 10.1183/09031936.02.00762001  0.396
2001 Drent M, Jacobs J, Cobben N, Costabel U, Wouters E, Mulder P. Computer program supporting the diagnostic accuracy of cellular BALF analysis: a new release Respiratory Medicine. 95: 781-786. PMID 11601741 DOI: 10.1053/Rmed.2001.1153  0.325
2001 van Belle AF, Lamers RJ, ten Velde GP, Wouters EF. Diagnostic yield of computed tomography and densitometric measurements of the lung in thoracoscopically-defined idiopathic spontaneous pneumothorax. Respiratory Medicine. 95: 292-6. PMID 11316112 DOI: 10.1053/Rmed.2001.1037  0.35
2001 Langendijk JA, Aaronson NK, de Jong JM, ten Velde GP, Muller MJ, Lamers RJ, Slotman BJ, Wouters EF. Prospective study on quality of life before and after radical radiotherapy in non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 2123-33. PMID 11304764 DOI: 10.1200/Jco.2001.19.8.2123  0.496
2000 Langendijk JA, Aaronson NK, ten Velde GP, de Jong JM, Muller MJ, Wouters EF. Pretreatment quality of life of inoperable non-small cell lung cancer patients referred for primary radiotherapy. Acta Oncologica (Stockholm, Sweden). 39: 949-58. PMID 11207002 DOI: 10.1080/02841860050215936  0.333
2000 Drent M, Verbraecken J, Grinten Cvd, Wouters E. Fatigue associated with obstructive sleep apnea in a patient with sarcoidosis. Respiration. 67: 337-340. PMID 10867608 DOI: 10.1159/000029523  0.333
2000 Gosker H, Wouters E, Vusse GJvd, Schols A. Skeletal muscle dysfunction in chronic obstructive pulmonary disease and chronic heart failure: underlying mechanisms and therapy perspectives The American Journal of Clinical Nutrition. 71: 1033-1047. PMID 10799364 DOI: 10.1093/Ajcn/71.5.1033  0.351
2000 Langendijk JA, ten Velde GP, Aaronson NK, de Jong JM, Muller MJ, Wouters EF. Quality of life after palliative radiotherapy in non-small cell lung cancer: a prospective study. International Journal of Radiation Oncology, Biology, Physics. 47: 149-55. PMID 10758317 DOI: 10.1016/S0360-3016(99)00540-4  0.486
1998 Baarends EM, van Marken Lichtenbelt WD, Wouters EF, Schols AM. Body-water compartments measured by bio-electrical impedance spectroscopy in patients with chronic obstructive pulmonary disease. Clinical Nutrition (Edinburgh, Scotland). 17: 15-22. PMID 10205310 DOI: 10.1016/S0261-5614(98)80038-1  0.358
1998 Langendijk JA, Tjwa MK, de Jong JM, ten Velde GP, Wouters EF. Massive haemoptysis after radiotherapy in inoperable non-small cell lung carcinoma: is endobronchial brachytherapy really a risk factor? Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 49: 175-83. PMID 10052884 DOI: 10.1016/S0167-8140(98)00103-0  0.46
1998 Wirnsberger RM, de Vries J, Breteler MH, van Heck GL, Wouters EF, Drent M. Evaluation of quality of life in sarcoidosis patients. Respiratory Medicine. 92: 750-6. PMID 9713635 DOI: 10.1016/S0954-6111(98)90007-5  0.348
1997 Baarends EM, Schols AM, van Marken Lichtenbelt WD, Wouters EF. Analysis of body water compartments in relation to tissue depletion in clinically stable patients with chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition. 65: 88-94. PMID 8988918 DOI: 10.1093/Ajcn/65.1.88  0.409
1997 Abenhaim L, Moride Y, Brenot F, Rich S, Benichou J, Kurz X, Higenbottam T, Oaldey C, Wouters E, Aubier M, Simonneau G, Begaud B. Appetite-suppressant drugs and the risk of primary pulmonary hypertension Acc Current Journal Review. 6: 81-82. DOI: 10.1016/S1062-1458(97)89579-7  0.314
1996 Abenhaim L, Moride Y, Brenot F, Rich S, Benichou J, Kurz X, Higenbottam T, Oakley C, Wouters E, Aubier M, Simonneau G, Bégaud B. Appetite-Suppressant Drugs and the Risk of Primary Pulmonary Hypertension The New England Journal of Medicine. 335: 609-616. PMID 8692238 DOI: 10.1056/Nejm199608293350901  0.362
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