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J. L. Kiappes - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 
Area:
Medicinal Chemistry, Organic Synthesis, Virology
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC, Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, ... ... Kiappes JL, et al. Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science (New York, N.Y.). 382: eabo7201. PMID 37943932 DOI: 10.1126/science.abo7201  0.672
2023 Guay KP, Ibba R, Kiappes JL, Vasiljević S, Bonì F, De Benedictis M, Zeni I, Le Cornu JD, Hensen M, Chandran AV, Kantsadi AL, Caputo AT, Blanco Capurro JI, Bayo Y, Hill JC, et al. A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint. Iscience. 26: 107919. PMID 37822503 DOI: 10.1016/j.isci.2023.107919  0.646
2021 Karade SS, Hill ML, Kiappes JL, Manne R, Aakula B, Zitzmann N, Warfield KL, Treston AM, Mariuzza RA. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. Journal of Medicinal Chemistry. 64: 18010-18024. PMID 34870992 DOI: 10.1021/acs.jmedchem.1c01377  0.729
2021 Brun J, Vasiljevic S, Gangadharan B, Hensen M, V Chandran A, Hill ML, Kiappes JL, Dwek RA, Alonzi DS, Struwe WB, Zitzmann N. Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike. Acs Central Science. 7: 586-593. PMID 34056088 DOI: 10.1021/acscentsci.1c00058  0.673
2021 Brun J, Vasiljevic S, Gangadharan B, Hensen M, V. Chandran A, Hill ML, Kiappes J, Dwek RA, Alonzi DS, Struwe WB, Zitzmann N. Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike Acs Central Science. 7: 586-593. DOI: 10.1021/acscentsci.1c00058  0.651
2020 Warfield K, Alonzi DS, Hill J, Caputo A, Roversi P, Kiappes JL, Sheets N, Duchars M, Dwek R, Biggins J, Barnard DL, Shresta S, Treston A, Zitzmann N. Targeting ER α-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections. Journal of Medicinal Chemistry. PMID 32227946 DOI: 10.1021/Acs.Jmedchem.0C00067  0.718
2019 Wai Haan Y, M. Al-Bajalan H, Eukun Sage E, Elangovan D, Mat Yajit NL, Sarizan NM, Zitzmann N, Kiappes JL, Hasbullah SA, Ismail NH, Mackeen MM. α-GLUCOSIDASE INHIBITION OF LACTONE INTERMEDIATES OF THE IMINOSUGAR DEOXYNOJIRIMYCIN Jurnal Teknologi. 81. DOI: 10.11113/JT.V81.13079  0.686
2018 Caputo AT, Alonzi DS, Kiappes JL, Struwe WB, Cross A, Basu S, Darlot B, Roversi P, Zitzmann N. Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II. Advances in Experimental Medicine and Biology. 1062: 265-276. PMID 29845539 DOI: 10.1007/978-981-10-8727-1_19  0.721
2017 Kiappes JL, Hill ML, Alonzi DS, Miller JL, Iwaki R, Sayce AC, Caputo AT, Kato A, Zitzmann N. ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II exhibiting anti-flaviviral activity. Acs Chemical Biology. PMID 29161006 DOI: 10.1021/Acschembio.7B00870  0.703
2016 Caputo AT, Alonzi DS, Marti L, Reca IB, Kiappes JL, Struwe WB, Cross A, Basu S, Lowe ED, Darlot B, Santino A, Roversi P, Zitzmann N. Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proceedings of the National Academy of Sciences of the United States of America. PMID 27462106 DOI: 10.1073/Pnas.1604463113  0.732
2016 Sayce AC, Alonzi DS, Killingbeck SS, Tyrrell BE, Hill ML, Caputo AT, Iwaki R, Kinami K, Ide D, Kiappes JL, Beatty PR, Kato A, Harris E, Dwek RA, Miller JL, et al. Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases-Not Glycolipid Processing Enzymes. Plos Neglected Tropical Diseases. 10: e0004524. PMID 26974655 DOI: 10.1371/Journal.Pntd.0004524  0.734
2016 Warfield KL, Plummer EM, Sayce AC, Alonzi DS, Tang W, Tyrrell BE, Hill ML, Caputo AT, Killingbeck SS, Beatty PR, Harris E, Iwaki R, Kinami K, Ide D, Kiappes JL, et al. Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4. Antiviral Research. PMID 26946111 DOI: 10.1016/J.Antiviral.2016.03.001  0.715
2015 Kato A, Hirokami Y, Kinami K, Tsuji Y, Miyawaki S, Adachi I, Hollinshead J, Nash RJ, Kiappes JL, Zitzmann N, Cha JK, Molyneux RJ, Fleet GW, Asano N. Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors. Phytochemistry. 111: 124-31. PMID 25583438 DOI: 10.1016/J.Phytochem.2014.12.011  0.712
2011 Nicolaou KC, Kiappes JL, Tian W, Gondi VB, Becker J. Synthesis of the carboline disaccharide domain of shishijimicin A. Organic Letters. 13: 3924-7. PMID 21711032 DOI: 10.1021/Ol201444T  0.681
2008 Sasaki T, Osgood AJ, Kiappes JL, Kelly KF, Tour JM. Synthesis of a porphyrin-fullerene pinwheel. Organic Letters. 10: 1377-80. PMID 18314994 DOI: 10.1021/Ol7029917  0.319
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