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Peiyu Xu - Publications

Affiliations: 
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, Shanghai Shi, China 
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu H, Guo S, Dai A, Xu P, Li X, Huang S, He X, Wu K, Zhang X, Yang D, Xie X, Xu HE. Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Research. PMID 38744981 DOI: 10.1038/s41422-024-00963-y  0.441
2024 Chen Z, Yu J, Wang H, Xu P, Fan L, Sun F, Huang S, Zhang P, Huang H, Gu S, Zhang B, Zhou Y, Wan X, Pei G, Xu HE, et al. Flexible scaffold-based cheminformatics approach for polypharmacological drug design. Cell. PMID 38552625 DOI: 10.1016/j.cell.2024.02.034  0.432
2023 Liu H, Zheng Y, Wang Y, Wang Y, He X, Xu P, Huang S, Yuan Q, Zhang X, Wang L, Jiang K, Chen H, Li Z, Liu W, Wang S, et al. Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature. PMID 37935377 DOI: 10.1038/s41586-023-06775-1  0.502
2023 Guo L, Zhang Y, Fang G, Tie L, Zhuang Y, Xue C, Liu Q, Zhang M, Zhu K, You C, Xu P, Yuan Q, Zhang C, Liu L, Rong N, et al. Ligand recognition and G protein coupling of the human itch receptor MRGPRX1. Nature Communications. 14: 5004. PMID 37591889 DOI: 10.1038/s41467-023-40705-z  0.447
2023 Xu P, Huang S, Krumm BE, Zhuang Y, Mao C, Zhang Y, Wang Y, Huang XP, Liu YF, He X, Li H, Yin W, Jiang Y, Zhang Y, Roth BL, et al. Structural genomics of the human dopamine receptor system. Cell Research. PMID 37221270 DOI: 10.1038/s41422-023-00808-0  0.517
2023 You C, Zhang Y, Xu Y, Xu P, Li Z, Li H, Huang S, Chen Z, Li J, Xu HE, Jiang Y. Structural basis for motilin and erythromycin recognition by motilin receptor. Science Advances. 9: eade9020. PMID 36921049 DOI: 10.1126/sciadv.ade9020  0.527
2023 Duan J, Xu P, Zhang H, Luan X, Yang J, He X, Mao C, Shen DD, Ji Y, Cheng X, Jiang H, Jiang Y, Zhang S, Zhang Y, Xu HE. Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nature Communications. 14: 519. PMID 36720854 DOI: 10.1038/s41467-023-36170-3  0.456
2022 Xu P, Huang S, Guo S, Yun Y, Cheng X, He X, Cai P, Lan Y, Zhou H, Jiang H, Jiang Y, Xie X, Xu HE. Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119. Nature Structural & Molecular Biology. PMID 35970999 DOI: 10.1038/s41594-022-00816-5  0.527
2022 Duan J, Xu P, Luan X, Ji Y, He X, Song N, Yuan Q, Jin Y, Cheng X, Jiang H, Zheng J, Zhang S, Jiang Y, Xu HE. Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature. PMID 35940204 DOI: 10.1038/s41586-022-05173-3  0.42
2022 Huang S, Xu P, Shen DD, Simon IA, Mao C, Tan Y, Zhang H, Harpsøe K, Li H, Zhang Y, You C, Yu X, Jiang Y, Zhang Y, Gloriam DE, et al. GPCRs steer G and G selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors. Molecular Cell. PMID 35714614 DOI: 10.1016/j.molcel.2022.05.031  0.412
2022 Tan Y, Xu P, Huang S, Yang G, Zhou F, He X, Ma H, Xu HE, Jiang Y. Structural insights into the ligand binding and G coupling of serotonin receptor 5-HT. Cell Discovery. 8: 50. PMID 35610220 DOI: 10.1038/s41421-022-00412-3  0.411
2022 Shao Z, Tan Y, Shen Q, Hou L, Yao B, Qin J, Xu P, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, et al. Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell Discovery. 8: 44. PMID 35570218 DOI: 10.1038/s41421-022-00403-4  0.532
2022 You C, Zhang Y, Xu P, Huang S, Yin W, Eric Xu H, Jiang Y. Structural insights into the peptide selectivity and activation of human neuromedin U receptors. Nature Communications. 13: 2045. PMID 35440625 DOI: 10.1038/s41467-022-29683-w  0.458
2022 Duan J, Shen DD, Zhao T, Guo S, He X, Yin W, Xu P, Ji Y, Chen LN, Liu J, Zhang H, Liu Q, Shi Y, Cheng X, Jiang H, et al. Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors. Nature Communications. 13: 1364. PMID 35292680 DOI: 10.1038/s41467-022-29072-3  0.46
2021 Duan J, Xu P, Cheng X, Mao C, Croll T, He X, Shi J, Luan X, Yin W, You E, Liu Q, Zhang S, Jiang H, Zhang Y, Jiang Y, et al. Structures of full-length glycoprotein hormone receptor signalling complexes. Nature. PMID 34552239 DOI: 10.1038/s41586-021-03924-2  0.493
2021 Wang Y, Guo S, Zhuang Y, Yun Y, Xu P, He X, Guo J, Yin W, Xu HE, Xie X, Jiang Y. Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor. Nature Communications. 12: 5064. PMID 34417468 DOI: 10.1038/s41467-021-25364-2  0.512
2021 Huang S, Xu P, Tan Y, You C, Zhang Y, Jiang Y, Xu HE. Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT-G protein complex. Cell Research. PMID 34239069 DOI: 10.1038/s41422-021-00527-4  0.422
2021 Cong Z, Chen LN, Ma H, Zhou Q, Zou X, Ye C, Dai A, Liu Q, Huang W, Sun X, Wang X, Xu P, Zhao L, Xia T, Zhong W, et al. Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nature Communications. 12: 3763. PMID 34145245 DOI: 10.1038/s41467-021-24058-z  0.399
2021 Xu P, Huang S, Zhang H, Mao C, Zhou XE, Cheng X, Simon IA, Shen DD, Yen HY, Robinson CV, Harpsøe K, Svensson B, Guo J, Jiang H, Gloriam DE, et al. Structural insights into the lipid and ligand regulation of serotonin receptors. Nature. PMID 33762731 DOI: 10.1038/s41586-021-03376-8  0.339
2021 Zhuang Y, Xu P, Mao C, Wang L, Krumm B, Zhou XE, Huang S, Liu H, Cheng X, Huang XP, Shen DD, Xu T, Liu YF, Wang Y, Guo J, et al. Structural insights into the human D1 and D2 dopamine receptor signaling complexes. Cell. PMID 33571431 DOI: 10.1016/j.cell.2021.01.027  0.48
2021 Xu P, Huang S, Mao C, Krumm BE, Zhou XE, Tan Y, Huang XP, Liu Y, Shen DD, Jiang Y, Yu X, Jiang H, Melcher K, Roth BL, Cheng X, et al. Structures of the human dopamine D3 receptor-G complexes. Molecular Cell. PMID 33548201 DOI: 10.1016/j.molcel.2021.01.003  0.542
2020 Duan J, Shen DD, Zhou XE, Bi P, Liu QF, Tan YX, Zhuang YW, Zhang HB, Xu PY, Huang SJ, Ma SS, He XH, Melcher K, Zhang Y, Xu HE, et al. Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy. Nature Communications. 11: 4121. PMID 32807782 DOI: 10.1038/S41467-020-17933-8  0.556
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