Daniel T. Chiu - Publications

Affiliations: 
2000- Chemistry University of Washington, Seattle, Seattle, WA 
Area:
Analytical, Biological, Materials, and Physical Chemistry, Nanotechnology
Website:
http://depts.washington.edu/chem/people/faculty/chiu.html

209 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Qin Y, Wu L, Chiu DT. Dielectrophoresis-Assisted Self-Digitization Chip for High-Efficiency Single-Cell Analysis. Methods in Molecular Biology (Clifton, N.J.). 2689: 27-38. PMID 37430044 DOI: 10.1007/978-1-0716-3323-6_3  0.369
2022 Jiang Y, Zhang J, Jung SR, Chen H, Xu S, Chiu DT. High-Precision Mapping of Membrane Proteins on Synaptic Vesicles using Spectrally Encoded Super-Resolution Imaging. Angewandte Chemie (International Ed. in English). e202217889. PMID 36581589 DOI: 10.1002/anie.202217889  0.716
2022 Qin Y, Kreutz JE, Schneider T, Yen GS, Shah ES, Wu L, Chiu DT. A reinforced PDMS mold for hot embossing of cyclic olefin polymer in the fabrication of microfluidic chips. Lab On a Chip. 22: 4729-4734. PMID 36367074 DOI: 10.1039/d2lc00857b  0.503
2022 Liu S, Liu Y, Zhang Z, Wang X, Yang Y, Sun K, Yu J, Chiu DT, Wu C. Near-Infrared Optical Transducer for Dynamic Imaging of Cerebrospinal Fluid Glucose in Brain Tumor. Analytical Chemistry. PMID 36206033 DOI: 10.1021/acs.analchem.2c02600  0.632
2022 Liu J, Fang X, Zhang Z, Liu Z, Liu J, Sun K, Yuan Z, Yu J, Chiu DT, Wu C. Long-Term Glucose Monitoring by Polymer-Dot Transducer in an Injectable Hydrogel Implant. Analytical Chemistry. PMID 35034435 DOI: 10.1021/acs.analchem.1c04730  0.636
2021 Wu L, Xu S, Wang J, Paguirigan AL, Radich JP, Qin Y, Chiu DT. Capillary-Mediated Single-Cell Dispenser. Analytical Chemistry. PMID 34319086 DOI: 10.1021/acs.analchem.1c01879  0.382
2021 Chen H, Yu J, Zhang J, Sun K, Ding Z, Jiang Y, Hu Q, Wu C, Chiu DT. Monitoring Metabolites Using an NAD(P)H-sensitive Polymer Dot and a Metabolite-specific Enzyme. Angewandte Chemie (International Ed. in English). PMID 34146440 DOI: 10.1002/anie.202106156  0.781
2021 Jiang Y, Andronico LA, Jung SR, Chen H, Fujimoto B, Vojtech L, Chiu DT. High-Throughput Counting and Superresolution Mapping of Tetraspanins on Exosomes using a Single-Molecule Sensitive Flow Technique and Transistor-like Semiconducting Polymer Dots. Angewandte Chemie (International Ed. in English). PMID 33797851 DOI: 10.1002/anie.202103282  0.737
2021 Jiang Y, Chen H, Men X, Sun Z, Yuan Z, Zhang X, Chiu DT, Wu C, McNeill J. Multimode Time-Resolved Superresolution Microscopy Revealing Chain Packing and Anisotropic Single Carrier Transport in Conjugated Polymer Nanowires. Nano Letters. PMID 33733782 DOI: 10.1021/acs.nanolett.1c00405  0.778
2021 Chen H, Yu J, Men X, Zhang J, Ding Z, Jiang Y, Wu C, Chiu DT. Reversible Ratiometric NADH Sensing Using Semiconducting Polymer Dots. Angewandte Chemie (International Ed. in English). PMID 33730372 DOI: 10.1002/anie.202100774  0.798
2021 Wang J, Staheli JP, Wu A, Kreutz JE, Hu Q, Wang J, Schneider T, Fujimoto BS, Qin Y, Yen GS, Weng B, Shibley K, Haynes H, Winer RL, Feng Q, ... Chiu DT, et al. Detection of 14 High-Risk Human Papillomaviruses Using Digital LAMP Assays on a Self-Digitization Chip. Analytical Chemistry. PMID 33534543 DOI: 10.1021/acs.analchem.0c04973  0.323
2021 Xu S, Wu L, Qin Y, Jiang Y, Sun K, Holcomb C, Gravett MG, Vojtech L, Schiro PG, Chiu DT. Sequential Ensemble-Decision Aliquot Ranking Isolation and Fluorescence Hybridization Identification of Rare Cells from Blood by Using Concentrated Peripheral Blood Mononuclear Cells. Analytical Chemistry. PMID 33528996 DOI: 10.1021/acs.analchem.0c04629  0.735
2021 Sun K, Liu S, Liu J, Ding Z, Jiang Y, Zhang J, Chen H, Yu J, Wu C, Chiu DT. Improving the Accuracy of Pdot-Based Continuous Glucose Monitoring by Using External Ratiometric Calibration. Analytical Chemistry. PMID 33417430 DOI: 10.1021/acs.analchem.0c04223  0.768
2020 Sun K, Ding Z, Zhang J, Chen H, Qin Y, Xu S, Wu C, Yu J, Chiu DT. Enhancing the Long-Term Stability of a Polymer Dot Glucose Transducer by Using an Enzymatic Cascade Reaction System. Advanced Healthcare Materials. e2001019. PMID 33094566 DOI: 10.1002/adhm.202001019  0.765
2020 Jiang Y, Hu Q, Chen H, Zhang J, Chiu DT, McNeill JD. Dual-Mode Superresolution Imaging using Charge Transfer Dynamics in Semiconducting Polymer Dots. Angewandte Chemie (International Ed. in English). PMID 32521111 DOI: 10.1002/Anie.202006348  0.788
2020 Wu MH, Lin CN, Chiu DT, Chen ST. Kynurenine/Tryptophan Ratio Predicts Angiotensin Receptor Blocker Responsiveness in Patients with Diabetic Kidney Disease. Diagnostics (Basel, Switzerland). 10. PMID 32283658 DOI: 10.3390/diagnostics10040207  0.43
2020 Liu Z, Liu J, Zhang Z, Sun Z, Shao X, Guo J, Xi L, Yuan Z, Zhang X, Chiu DT, Wu C. Narrow-band polymer dots with pronounced fluorescence fluctuations for dual-color super-resolution imaging. Nanoscale. PMID 32215435 DOI: 10.1039/D0Nr00347F  0.704
2019 Johnson ES, Xu S, Yu HM, Fang WF, Qin YL, Wu L, Wang J, Zhao M, Schiro PG, Fujimoto B, Chen JL, Chiu DT. Isolating Rare Cells and Circulating Tumor Cells with High Purity by Sequential eDAR. Analytical Chemistry. PMID 31646861 DOI: 10.1021/Acs.Analchem.9B03690  0.751
2019 Qin YL, Wu L, Wang J, Han R, Shen J, Wang J, Xu S, Paguirigan AL, Smith JL, Radich JP, Chiu DT. A Fluorescence-Activated Single-Droplet Dispenser for High Accuracy Single-Droplet and Single-Cell Sorting and Dispensing. Analytical Chemistry. PMID 31050286 DOI: 10.1021/Acs.Analchem.9B01017  0.483
2019 Chen L, Chen D, Jiang Y, Zhang J, Yu J, DuFort CC, Hingorani SR, Zhang X, Wu C, Chiu DT. BODIPY-Based Donor/Donor-Acceptor System: Towards Highly Efficient Long Wavelength-Excitable Near-IR Polymer Dots with Narrow and Strong Absorption Features. Angewandte Chemie (International Ed. in English). PMID 30912228 DOI: 10.1002/Anie.201902077  0.687
2019 Hassan AM, Wu X, Jarrett JW, Xu S, Yu J, Miller DR, Perillo EP, Liu YL, Chiu DT, Yeh HC, Dunn AK. Polymer dots enable deep multiphoton fluorescence imaging of microvasculature. Biomedical Optics Express. 10: 584-599. PMID 30800501 DOI: 10.1364/Boe.10.000584  0.318
2019 Yen GS, Fujimoto BS, Schneider T, Kreutz JE, Chiu DT. Statistical Analysis of Non-Uniform Volume Distributions for Droplet-based Digital PCR Assays. Journal of the American Chemical Society. PMID 30605325 DOI: 10.1021/Jacs.8B09073  0.45
2018 Wang J, Kreutz JE, Thompson AM, Qin Y, Sheen AM, Wang J, Wu L, Xu S, Chang M, Raugi DN, Smith RA, Gottlieb GS, Chiu DT. SD-chip enabled quantitative detection of HIV RNA using digital nucleic acid sequence-based amplification (dNASBA). Lab On a Chip. PMID 30351338 DOI: 10.1039/C8Lc00956B  0.378
2018 Kuo CT, Wu IC, Chen L, Yu J, Wu L, Chiu DT. Improving the Photostability of Semiconducting Polymer Dots Using Buffers. Analytical Chemistry. PMID 30277754 DOI: 10.1021/Acs.Analchem.8B03104  0.47
2018 Wu X, DeGottardi Q, Wu IC, Wu L, Yu J, Kwok WW, Chiu DT. Ratiometric Barcoding for Mass Cytometry. Analytical Chemistry. PMID 30139253 DOI: 10.1021/Acs.Analchem.8B03201  0.42
2018 Qin Y, Wu L, Schneider T, Yen G, Wang J, Xu S, Li M, Paguirigan AL, Smith JL, Radich JP, Anand RK, Chiu DT. Self-Digitization Dielectrophoretic (SD-DEP) Chip for High Efficiency Single-Cell Capture, On-Demand Compartmentalization, and Downstream Nucleic-Acid Analysis. Angewandte Chemie (International Ed. in English). PMID 30003660 DOI: 10.1002/Anie.201807314  0.56
2018 Andronico LA, Chen L, Mirasoli M, Guardigli M, Quintavalla A, Lombardo M, Trombini C, Chiu DT, Roda A. Thermochemiluminescent semiconducting polymer dots as sensitive nanoprobes for reagentless immunoassay. Nanoscale. PMID 29995031 DOI: 10.1039/C8Nr03092H  0.355
2018 Thompson AM, Smith JL, Monroe LD, Kreutz JE, Schneider T, Fujimoto BS, Chiu DT, Radich JP, Paguirigan AL. Self-digitization chip for single-cell genotyping of cancer-related mutations. Plos One. 13: e0196801. PMID 29718986 DOI: 10.1371/Journal.Pone.0196801  0.452
2018 Sun K, Yang Y, Zhou H, Yin S, Qin W, Yu J, Chiu DT, Yuan Z, Zhang X, Wu C. Ultrabright Polymer-Dot Transducer Enabled Wireless Glucose Monitoring via a Smartphone. Acs Nano. PMID 29694016 DOI: 10.1021/Acsnano.8B02188  0.682
2018 Chen H, Fang X, Jin Y, Hu X, Yin M, Men X, Chen N, Fan C, Chiu DT, Wan Y, Wu C. Semiconducting Polymer Nanocavities: Porogenic Synthesis, Tunable Host-Guest Interactions, and Enhanced Drug/siRNA Delivery. Small (Weinheim An Der Bergstrasse, Germany). e1800239. PMID 29682859 DOI: 10.1002/Smll.201800239  0.791
2018 Jung SR, Han R, Sun W, Jiang Y, Fujimoto BS, Yu J, Kuo CT, Rong Y, Zhou XH, Chiu DT. A single-molecule flow platform for the quantification of biomolecules attached to single nanoparticles. Analytical Chemistry. PMID 29672026 DOI: 10.1021/Acs.Analchem.8B00024  0.437
2018 Chen D, Yuan Y, Yu J, Chiu DT, Wu C. Purification of Semiconducting Polymer Dots by Size Exclusion Chromatography Prior to Cytotoxicity Assay and Stem Cell Labeling. Analytical Chemistry. PMID 29569904 DOI: 10.1021/Acs.Analchem.8B00095  0.717
2017 Chiu DT, Wu X, Degottardi Q, Wu IC, Yu J, Wu L, Ye F, Kuo CT, Kwok WW. Lanthanide-Coordinated Semiconducting Polymer Dots that Function for both Flow Cytometry and Mass Cytometry. Angewandte Chemie (International Ed. in English). PMID 28941061 DOI: 10.1002/Anie.201708463  0.451
2017 Jung SR, Fujimoto BS, Chiu DT. Quantitative microscopy based on single-molecule fluorescence. Current Opinion in Chemical Biology. 39: 64-73. PMID 28623730 DOI: 10.1016/J.Cbpa.2017.06.004  0.356
2017 Chen D, Wu IC, Liu Z, Tang Y, Chen H, Yu J, Wu C, Chiu DT. Semiconducting polymer dots with bright narrow-band emission at 800 nm for biological applications. Chemical Science. 8: 3390-3398. PMID 28507710 DOI: 10.1039/C7Sc00441A  0.8
2017 Kuo CT, Peng HS, Rong Y, Yu J, Sun W, Fujimoto BS, Chiu DT. Optically Encoded Semiconducting Polymer Dots with Single-Wavelength Excitation for Barcoding and Tracking of Single Cells. Analytical Chemistry. PMID 28499337 DOI: 10.1021/Acs.Analchem.7B01214  0.456
2017 Wu L, Wu IC, DuFort CC, Carlson MA, Wu X, Chen L, Kuo CT, Qin Y, Yu J, Hingorani SR, Chiu DT. A Photostable Ratiometric Pdot Probe for In Vitro and In Vivo Imaging of Hypochlorous Acid. Journal of the American Chemical Society. PMID 28459559 DOI: 10.1021/Jacs.7B01545  0.478
2017 Yu J, Rong Y, Kuo CT, Zhou XH, Chiu DT. Recent Advances in the Development of Highly Luminescent Semiconducting Polymer Dots and Nanoparticles for Biological Imaging and Medicine. Analytical Chemistry. 89: 42-56. PMID 28105818 DOI: 10.1021/Acs.Analchem.6B04672  0.311
2016 Wu X, Wu L, Wu IC, Chiu DT. Copper (II)-doped semiconducting polymer dots for nitroxyl imaging in live cells. Rsc Advances. 6: 103618-103621. PMID 28529727 DOI: 10.1039/C6Ra20439B  0.468
2016 Sun K, Tang Y, Li Q, Yin S, Qin W, Yu J, Chiu DT, Liu Y, Yuan Z, Zhang X, Wu C. In Vivo Dynamic Monitoring of Small Molecules with Implantable Polymer-Dot Transducer. Acs Nano. PMID 27303785 DOI: 10.1021/Acsnano.6B02386  0.697
2016 Kuo CT, Thompson AM, Gallina ME, Ye F, Johnson ES, Sun W, Zhao M, Yu J, Wu IC, Fujimoto B, DuFort CC, Carlson MA, Hingorani SR, Paguirigan AL, Radich JP, ... Chiu DT, et al. Optical painting and fluorescence activated sorting of single adherent cells labelled with photoswitchable Pdots. Nature Communications. 7: 11468. PMID 27118210 DOI: 10.1038/Ncomms11468  0.444
2016 Yen GS, Edgar JS, Yoon SH, Huang Y, Heron SR, Chiu DT, Goodlett DR. Polydimethylsiloxane microchannel coupled to surface acoustic wave nebulization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 30: 1096-100. PMID 27003047 DOI: 10.1002/Rcm.7531  0.701
2015 Zhao M, Wei B, Nelson WC, Schiro PG, Chiu DT. Simultaneous and selective isolation of multiple subpopulations of rare cells from peripheral blood using ensemble-decision aliquot ranking (eDAR). Lab On a Chip. PMID 26160592 DOI: 10.1039/C5Lc00384A  0.727
2015 Ye F, Smith PB, Chiu DT. Ultrasensitive Protein Detection on Dot Blots and Western Blots with Semiconducting Polymer Dots. Methods in Molecular Biology (Clifton, N.J.). 1314: 131-7. PMID 26139261 DOI: 10.1007/978-1-4939-2718-0_14  0.595
2015 Ye F, White CC, Jin Y, Hu X, Hayden S, Zhang X, Gao X, Kavanagh TJ, Chiu DT. Toxicity and oxidative stress induced by semiconducting polymer dots in RAW264.7 mouse macrophages. Nanoscale. 7: 10085-93. PMID 25978523 DOI: 10.1039/C5Nr01857A  0.303
2015 Zhang Y, Ye F, Sun W, Yu J, Wu IC, Rong Y, Zhang Y, Chiu DT. Light-induced Crosslinkable Semiconducting Polymer Dots. Chemical Science (Royal Society of Chemistry : 2010). 6: 2102-2109. PMID 25709806 DOI: 10.1039/C4Sc03959A  0.461
2015 Anand RK, Johnson ES, Chiu DT. Negative dielectrophoretic capture and repulsion of single cells at a bipolar electrode: the impact of faradaic ion enrichment and depletion. Journal of the American Chemical Society. 137: 776-83. PMID 25562315 DOI: 10.1021/Ja5102689  0.301
2015 Peng HS, Chiu DT. Soft fluorescent nanomaterials for biological and biomedical imaging. Chemical Society Reviews. 44: 4699-722. PMID 25531691 DOI: 10.1039/C4Cs00294F  0.332
2015 Ye F, Sun W, Zhang Y, Wu C, Zhang X, Yu J, Rong Y, Zhang M, Chiu DT. Single-chain semiconducting polymer dots. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 499-505. PMID 25521606 DOI: 10.1021/La5038684  0.693
2015 Wu IC, Yu J, Ye F, Rong Y, Gallina ME, Fujimoto BS, Zhang Y, Chan YH, Sun W, Zhou XH, Wu C, Chiu DT. Squaraine-based polymer dots with narrow, bright near-infrared fluorescence for biological applications. Journal of the American Chemical Society. 137: 173-8. PMID 25494172 DOI: 10.1021/Ja5123045  0.734
2014 Rong Y, Yu J, Zhang X, Sun W, Ye F, Wu IC, Zhang Y, Hayden S, Zhang Y, Wu C, Chiu DT. Yellow Fluorescent Semiconducting Polymer Dots with High Brightness, Small Size, and Narrow Emission for Biological Applications. Acs Macro Letters. 3: 1051-1054. PMID 25419486 DOI: 10.1021/Mz500383C  0.72
2014 Thompson AM, Gansen A, Paguirigan AL, Kreutz JE, Radich JP, Chiu DT. Self-digitization microfluidic chip for absolute quantification of mRNA in single cells. Analytical Chemistry. 86: 12308-14. PMID 25390242 DOI: 10.1021/Ac5035924  0.303
2014 Liu D, Hakimi B, Volny M, Rolfs J, Anand RK, Turecek F, Chiu DT. Modulating patterns of two-phase flow with electric fields. Biomicrofluidics. 8: 044106. PMID 25379091 DOI: 10.1063/1.4891099  0.469
2014 Chang K, Liu Z, Chen H, Sheng L, Zhang SX, Chiu DT, Yin S, Wu C, Qin W. Conjugated polymer dots for ultra-stable full-color fluorescence patterning. Small (Weinheim An Der Bergstrasse, Germany). 10: 4270-5. PMID 25048985 DOI: 10.1002/Smll.201401436  0.795
2014 Li Q, Zhang J, Sun W, Yu J, Wu C, Qin W, Chiu DT. Europium-complex-grafted polymer dots for amplified quenching and cellular imaging applications. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 8607-14. PMID 24976495 DOI: 10.1021/La501876M  0.716
2014 Thompson AM, Paguirigan AL, Kreutz JE, Radich JP, Chiu DT. Microfluidics for single-cell genetic analysis. Lab On a Chip. 14: 3135-42. PMID 24789374 DOI: 10.1039/C4Lc00175C  0.307
2014 Ye F, Wu C, Sun W, Yu J, Zhang X, Rong Y, Zhang Y, Wu IC, Chan YH, Chiu DT. Semiconducting polymer dots with monofunctional groups. Chemical Communications (Cambridge, England). 50: 5604-7. PMID 24728589 DOI: 10.1039/C4Cc01689K  0.698
2014 Chiu DT, Shapiro NI, Sun BC, Mottley JL, Grossman SA. Are echocardiography, telemetry, ambulatory electrocardiography monitoring, and cardiac enzymes in emergency department patients presenting with syncope useful tests? A preliminary investigation. The Journal of Emergency Medicine. 47: 113-8. PMID 24698512 DOI: 10.1016/j.jemermed.2014.01.018  0.378
2014 Volný M, Rolfs J, Hakimi B, Fry?ák P, Schneider T, Liu D, Yen G, Chiu DT, Ture?ek F. Nanoliter segmented-flow sampling mass spectrometry with online compartmentalization. Analytical Chemistry. 86: 3647-52. PMID 24625074 DOI: 10.1021/Ac500365R  0.448
2013 Zhang X, Yu J, Rong Y, Ye F, Chiu DT, Uvdal K. High-intensity near-IR fluorescence in semiconducting polymer dots achieved by cascade FRET strategy. Chemical Science. 4: 2143-2151. PMID 28959389 DOI: 10.1039/C3Sc50222H  0.38
2013 Schneider T, Yen GS, Thompson AM, Burnham DR, Chiu DT. Self-digitization of samples into a high-density microfluidic bottom-well array. Analytical Chemistry. 85: 10417-23. PMID 24099270 DOI: 10.1021/Ac402383N  0.441
2013 Zhao M, Nelson WC, Wei B, Schiro PG, Hakimi BM, Johnson ES, Anand RK, Gyurkey GS, White LM, Whiting SH, Coveler AL, Chiu DT. New generation of ensemble-decision aliquot ranking based on simplified microfluidic components for large-capacity trapping of circulating tumor cells. Analytical Chemistry. 85: 9671-7. PMID 24087951 DOI: 10.1021/Ac401985R  0.733
2013 Sun W, Yu J, Deng R, Rong Y, Fujimoto B, Wu C, Zhang H, Chiu DT. Semiconducting polymer dots doped with europium complexes showing ultranarrow emission and long luminescence lifetime for time-gated cellular imaging. Angewandte Chemie (International Ed. in English). 52: 11294-7. PMID 24030955 DOI: 10.1002/Anie.201304822  0.721
2013 Li Q, Sun K, Chang K, Yu J, Chiu DT, Wu C, Qin W. Ratiometric luminescent detection of bacterial spores with terbium chelated semiconducting polymer dots. Analytical Chemistry. 85: 9087-91. PMID 23964730 DOI: 10.1021/Ac4016616  0.692
2013 Zhang Y, Yu J, Gallina ME, Sun W, Rong Y, Chiu DT. Highly luminescent, fluorinated semiconducting polymer dots for cellular imaging and analysis. Chemical Communications (Cambridge, England). 49: 8256-8. PMID 23925590 DOI: 10.1039/C3Cc44048F  0.459
2013 Zeigler MB, Sun W, Rong Y, Chiu DT. Hybrid semiconducting polymer nanoparticles as polarization-sensitive fluorescent probes. Journal of the American Chemical Society. 135: 11453-6. PMID 23895535 DOI: 10.1021/ja404719f  0.324
2013 Liu D, Hakimi B, Volny M, Rolfs J, Chen X, Turecek F, Chiu DT. Controlled generation of double emulsions in air. Analytical Chemistry. 85: 6190-4. PMID 23767768 DOI: 10.1021/Ac400844P  0.474
2013 Ye F, Smith PB, Wu C, Chiu DT. Ultrasensitive detection of proteins on Western blots with semiconducting polymer dots. Macromolecular Rapid Communications. 34: 785-90. PMID 23637077 DOI: 10.1002/Marc.201200809  0.776
2013 Neupane B, Chen F, Sun W, Chiu DT, Wang G. Tuning donut profile for spatial resolution in stimulated emission depletion microscopy. The Review of Scientific Instruments. 84: 043701. PMID 23635197 DOI: 10.1063/1.4799665  0.356
2013 Sun W, Ye F, Gallina ME, Yu J, Wu C, Chiu DT. Lyophilization of semiconducting polymer dot bioconjugates. Analytical Chemistry. 85: 4316-20. PMID 23600767 DOI: 10.1021/Ac4007123  0.732
2013 Zeigler MB, Chiu DT. Single-cell nanosurgery. Methods in Molecular Biology (Clifton, N.J.). 991: 139-48. PMID 23546666 DOI: 10.1007/978-1-62703-336-7_14  0.308
2013 Schneider T, Kreutz J, Chiu DT. The potential impact of droplet microfluidics in biology. Analytical Chemistry. 85: 3476-82. PMID 23495853 DOI: 10.1021/Ac400257C  0.467
2013 Sgro AE, Bajjalieh SM, Chiu DT. Single-axonal organelle analysis method reveals new protein-motor associations. Acs Chemical Neuroscience. 4: 277-84. PMID 23421679 DOI: 10.1021/Cn300136Y  0.728
2013 Zhao M, Schiro PG, Kuo JS, Koehler KM, Sabath DE, Popov V, Feng Q, Chiu DT. An automated high-throughput counting method for screening circulating tumor cells in peripheral blood. Analytical Chemistry. 85: 2465-71. PMID 23387387 DOI: 10.1021/Ac400193B  0.725
2013 Wu C, Chiu DT. Highly fluorescent semiconducting polymer dots for biology and medicine. Angewandte Chemie (International Ed. in English). 52: 3086-109. PMID 23307291 DOI: 10.1002/Anie.201205133  0.696
2013 Rong Y, Wu C, Yu J, Zhang X, Ye F, Zeigler M, Gallina ME, Wu IC, Zhang Y, Chan YH, Sun W, Uvdal K, Chiu DT. Multicolor fluorescent semiconducting polymer dots with narrow emissions and high brightness. Acs Nano. 7: 376-84. PMID 23282278 DOI: 10.1021/Nn304376Z  0.733
2013 Sun W, Yu J, Ye F, Rong Y, Chiu DT. Highly fluorescent semiconducting polymer dots for single-molecule imaging and biosensing Proceedings of Spie - the International Society For Optical Engineering. 8812. DOI: 10.1117/12.2028187  0.374
2013 Wu C, Chiu DT. Stark fluoreszierende halbleitende Polymerpunkte für Biologie und Medizin Angewandte Chemie. 125: 3164-3190. DOI: 10.1002/Ange.201205133  0.632
2012 Gadd JC, Budzinski KL, Chan YH, Ye F, Chiu DT. Probing the interior of synaptic vesicles with internalized nanoparticles. Proceedings of Spie--the International Society For Optical Engineering. 8232. PMID 31693003 DOI: 10.1117/12.905091  0.778
2012 Gadd JC, Fujimoto BS, Bajjalieh SM, Chiu DT. Single-molecule fluorescence quantification with a photobleached internal standard. Analytical Chemistry. 84: 10522-5. PMID 23210507 DOI: 10.1021/Ac303032M  0.797
2012 Sun W, Hayden S, Jin Y, Rong Y, Yu J, Ye F, Chan YH, Zeigler M, Wu C, Chiu DT. A versatile method for generating semiconducting polymer dot nanocomposites. Nanoscale. 4: 7246-9. PMID 23072832 DOI: 10.1039/C2Nr32055J  0.707
2012 Chan YH, Gallina ME, Zhang X, Wu IC, Jin Y, Sun W, Chiu DT. Reversible photoswitching of spiropyran-conjugated semiconducting polymer dots. Analytical Chemistry. 84: 9431-8. PMID 23033991 DOI: 10.1021/Ac302245T  0.45
2012 Anand RK, Chiu DT. Analytical tools for characterizing heterogeneity in organelle content. Current Opinion in Chemical Biology. 16: 391-9. PMID 22694875 DOI: 10.1016/J.Cbpa.2012.05.187  0.341
2012 Yu J, Wu C, Zhang X, Ye F, Gallina ME, Rong Y, Wu IC, Sun W, Chan YH, Chiu DT. Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for specific cellular imaging. Advanced Materials (Deerfield Beach, Fla.). 24: 3498-504. PMID 22684783 DOI: 10.1002/Adma.201201245  0.72
2012 Zhang X, Yu J, Wu C, Jin Y, Rong Y, Ye F, Chiu DT. Importance of having low-density functional groups for generating high-performance semiconducting polymer dots. Acs Nano. 6: 5429-39. PMID 22607220 DOI: 10.1021/Nn301308W  0.708
2012 Schiro PG, Gadd JC, Yen GS, Chiu DT. High-throughput fluorescence-activated nanoscale subcellular sorter with single-molecule sensitivity. The Journal of Physical Chemistry. B. 116: 10490-5. PMID 22574902 DOI: 10.1021/Jp3019233  0.803
2012 Chan YH, Ye F, Gallina ME, Zhang X, Jin Y, Wu IC, Chiu DT. Hybrid semiconducting polymer dot-quantum dot with narrow-band emission, near-infrared fluorescence, and high brightness. Journal of the American Chemical Society. 134: 7309-12. PMID 22515545 DOI: 10.1021/Ja3022973  0.346
2012 Schiro PG, Zhao M, Kuo JS, Koehler KM, Sabath DE, Chiu DT. Sensitive and high-throughput isolation of rare cells from peripheral blood with ensemble-decision aliquot ranking. Angewandte Chemie (International Ed. in English). 51: 4618-22. PMID 22359315 DOI: 10.1002/Anie.201108695  0.721
2012 Jin Y, Ye F, Wu C, Chan YH, Chiu DT. Generation of functionalized and robust semiconducting polymer dots with polyelectrolytes. Chemical Communications (Cambridge, England). 48: 3161-3. PMID 22349364 DOI: 10.1039/C2Cc17703J  0.691
2012 Ye F, Wu C, Jin Y, Wang M, Chan YH, Yu J, Sun W, Hayden S, Chiu DT. A compact and highly fluorescent orange-emitting polymer dot for specific subcellular imaging. Chemical Communications (Cambridge, England). 48: 1778-80. PMID 22218705 DOI: 10.1039/C2Cc16486H  0.726
2012 Gadd JC, Budzinski KL, Chan YH, Ye F, Chiu DT. Probing the interior of synaptic vesicles with internalized nanoparticles Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8232. DOI: 10.1117/12.905091  0.773
2012 Schiro PG, Zhao M, Kuo JS, Koehler KM, Sabath DE, Chiu DT. Back Cover: Sensitive and High-Throughput Isolation of Rare Cells from Peripheral Blood with Ensemble-Decision Aliquot Ranking (Angew. Chem. Int. Ed. 19/2012) Angewandte Chemie International Edition. 51: 4754-4754. DOI: 10.1002/Anie.201201432  0.713
2012 Schiro PG, Zhao M, Kuo JS, Koehler KM, Sabath DE, Chiu DT. Rücktitelbild: Sensitive and High-Throughput Isolation of Rare Cells from Peripheral Blood with Ensemble-Decision Aliquot Ranking (Angew. Chem. 19/2012) Angewandte Chemie. 124: 4836-4836. DOI: 10.1002/Ange.201201432  0.712
2012 Yu J, Wu C, Zhang X, Ye F, Gallina ME, Rong Y, Wu I, Sun W, Chan Y, Chiu DT. Covalent Cross-Linking: Stable Functionalization of Small Semiconducting Polymer Dots via Covalent Cross-Linking and Their Application for Specific Cellular Imaging (Adv. Mater. 26/2012) Advanced Materials. 24: 3577-3577. DOI: 10.1002/Adma.201290160  0.677
2011 Mutch SA, Gadd JC, Fujimoto BS, Kensel-Hammes P, Schiro PG, Bajjalieh SM, Chiu DT. Determining the number of specific proteins in cellular compartments by quantitative microscopy. Nature Protocols. 6: 1953-68. PMID 22094731 DOI: 10.1038/Nprot.2011.414  0.783
2011 Budzinski KL, Zeigler M, Fujimoto BS, Bajjalieh SM, Chiu DT. Measurements of the acidification kinetics of single SynaptopHluorin vesicles. Biophysical Journal. 101: 1580-9. PMID 21961583 DOI: 10.1016/J.Bpj.2011.08.032  0.78
2011 Burnham DR, Schneider T, Chiu DT. Effects of aliasing on the fidelity of a two dimensional array of foci generated with a kinoform. Optics Express. 19: 17121-6. PMID 21935073 DOI: 10.1364/Oe.19.017121  0.427
2011 Budzinski KL, Sgro AE, Fujimoto BS, Gadd JC, Shuart NG, Gonen T, Bajjaleih SM, Chiu DT. Synaptosomes as a platform for loading nanoparticles into synaptic vesicles. Acs Chemical Neuroscience. 2: 236-241. PMID 21666849 DOI: 10.1021/Cn200009N  0.775
2011 Zeigler MB, Allen PB, Chiu DT. Probing rotational viscosity in synaptic vesicles. Biophysical Journal. 100: 2846-51. PMID 21641331 DOI: 10.1016/J.Bpj.2011.04.042  0.302
2011 Schneider T, Burnham DR, VanOrden J, Chiu DT. Systematic investigation of droplet generation at T-junctions. Lab On a Chip. 11: 2055-9. PMID 21589961 DOI: 10.1039/C1Lc20259F  0.438
2011 Ye F, Wu C, Jin Y, Chan YH, Zhang X, Chiu DT. Ratiometric temperature sensing with semiconducting polymer dots. Journal of the American Chemical Society. 133: 8146-9. PMID 21548583 DOI: 10.1021/Ja202945G  0.684
2011 Sgro AE, Nowak AL, Austin NS, Custer KL, Allen PB, Chiu DT, Bajjalieh SM. A high-throughput method for generating uniform microislands for autaptic neuronal cultures. Journal of Neuroscience Methods. 198: 230-5. PMID 21515305 DOI: 10.1016/J.Jneumeth.2011.04.012  0.728
2011 Wu C, Hansen SJ, Hou Q, Yu J, Zeigler M, Jin Y, Burnham DR, McNeill JD, Olson JM, Chiu DT. Design of highly emissive polymer dot bioconjugates for in vivo tumor targeting. Angewandte Chemie (International Ed. in English). 50: 3430-4. PMID 21381164 DOI: 10.1002/Anie.201007461  0.789
2011 Jin Y, Ye F, Zeigler M, Wu C, Chiu DT. Near-infrared fluorescent dye-doped semiconducting polymer dots. Acs Nano. 5: 1468-75. PMID 21280613 DOI: 10.1021/Nn103304M  0.715
2011 Mutch SA, Kensel-Hammes P, Gadd JC, Fujimoto BS, Allen RW, Schiro PG, Lorenz RM, Kuyper CL, Kuo JS, Bajjalieh SM, Chiu DT. Protein quantification at the single vesicle level reveals that a subset of synaptic vesicle proteins are trafficked with high precision. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1461-70. PMID 21273430 DOI: 10.1523/Jneurosci.3805-10.2011  0.763
2011 Chan YH, Wu C, Ye F, Jin Y, Smith PB, Chiu DT. Development of ultrabright semiconducting polymer dots for ratiometric pH sensing. Analytical Chemistry. 83: 1448-55. PMID 21244093 DOI: 10.1021/Ac103140X  0.739
2011 Chan YH, Jin Y, Wu C, Chiu DT. Copper(II) and iron(II) ion sensing with semiconducting polymer dots. Chemical Communications (Cambridge, England). 47: 2820-2. PMID 21240410 DOI: 10.1039/C0Cc04929H  0.69
2011 Yen GS, Fujimoto BS, Schneider T, Huynh DT, Jeffries GD, Chiu DT. A rapid and economical method for profiling feature heights during microfabrication. Lab On a Chip. 11: 974-7. PMID 21229183 DOI: 10.1039/C0Lc00470G  0.72
2010 Burnham DR, Schneider T, Chiu DT. Optical Trapping Enabled Parallel Delivery of Biological Stimuli with High Spatial and Temporal Resolution. Proceedings of Spie--the International Society For Optical Engineering. 7762: 77621T. PMID 24465114 DOI: 10.1117/12.862519  0.482
2010 Gregersen KA, Hill ZB, Gadd JC, Fujimoto BS, Maly DJ, Chiu DT. Intracellular delivery of bioactive molecules using light-addressable nanocapsules. Acs Nano. 4: 7603-11. PMID 21117640 DOI: 10.1021/Nn102345F  0.782
2010 Jeffries GD, Lorenz RM, Chiu DT. Ultrasensitive and high-throughput fluorescence analysis of droplet contents with orthogonal line confocal excitation. Analytical Chemistry. 82: 9948-54. PMID 21062029 DOI: 10.1021/Ac102173M  0.716
2010 Wu C, Jin Y, Schneider T, Burnham DR, Smith PB, Chiu DT. Ultrabright and bioorthogonal labeling of cellular targets using semiconducting polymer dots and click chemistry. Angewandte Chemie (International Ed. in English). 49: 9436-40. PMID 20979060 DOI: 10.1002/Anie.201004260  0.794
2010 Wu C, Schneider T, Zeigler M, Yu J, Schiro PG, Burnham DR, McNeill JD, Chiu DT. Bioconjugation of ultrabright semiconducting polymer dots for specific cellular targeting. Journal of the American Chemical Society. 132: 15410-7. PMID 20929226 DOI: 10.1021/Ja107196S  0.806
2010 Cohen DE, Schneider T, Wang M, Chiu DT. Self-digitization of sample volumes. Analytical Chemistry. 82: 5707-17. PMID 20550137 DOI: 10.1021/ac100713u  0.604
2010 Sgro AE, Chiu DT. Droplet freezing, docking, and the exchange of immiscible phase and surfactant around frozen droplets. Lab On a Chip. 10: 1873-7. PMID 20467690 DOI: 10.1039/C001108H  0.747
2010 Kuo JS, Zhao Y, Schiro PG, Ng L, Lim DS, Shelby JP, Chiu DT. Deformability considerations in filtration of biological cells. Lab On a Chip. 10: 837-42. PMID 20379567 DOI: 10.1039/B922301K  0.772
2010 Smith PB, Dendramis KA, Chiu DT. Investigating lyophilization of lipid nanocapsules with fluorescence correlation spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 10218-22. PMID 20302335 DOI: 10.1021/La1003808  0.575
2009 Jeffries GD, Milne G, Zhao Y, Lopez-Mariscal C, Chiu DT. Optofluidic generation of Laguerre-Gaussian beams. Optics Express. 17: 17555-62. PMID 19907539 DOI: 10.1364/Oe.17.017555  0.682
2009 Budzinski KL, Allen RW, Fujimoto BS, Kensel-Hammes P, Belnap DM, Bajjalieh SM, Chiu DT. Large structural change in isolated synaptic vesicles upon loading with neurotransmitter. Biophysical Journal. 97: 2577-84. PMID 19883601 DOI: 10.1016/J.Bpj.2009.08.032  0.775
2009 Kuo JS, Zhao Y, Ng L, Yen GS, Lorenz RM, Lim DS, Chiu DT. Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices. Lab On a Chip. 9: 1951-6. PMID 19532971 DOI: 10.1039/B902124H  0.309
2009 Chiu DT, Lorenz RM, Jeffries GD. Droplets for ultrasmall-volume analysis. Analytical Chemistry. 81: 5111-8. PMID 19507850 DOI: 10.1021/Ac900306Q  0.677
2009 Allen PB, Doepker BR, Chiu DT. High-throughput capillary-electrophoresis analysis of the contents of a single mitochondria. Analytical Chemistry. 81: 3784-91. PMID 19344146 DOI: 10.1021/Ac900099Y  0.338
2009 Kuo JS, Ng L, Yen GS, Lorenz RM, Schiro PG, Edgar JS, Zhao Y, Lim DS, Allen PB, Jeffries GD, Chiu DT. A new USP Class VI-compliant substrate for manufacturing disposable microfluidic devices. Lab On a Chip. 9: 870-6. PMID 19294296 DOI: 10.1039/B818873D  0.776
2009 Chiu DT, Lorenz RM. Chemistry and biology in femtoliter and picoliter volume droplets. Accounts of Chemical Research. 42: 649-58. PMID 19260732 DOI: 10.1021/Ar8002464  0.379
2009 Edgar JS, Milne G, Zhao Y, Pabbati CP, Lim DS, Chiu DT. Compartmentalization of chemically separated components into droplets. Angewandte Chemie (International Ed. in English). 48: 2719-22. PMID 19142923 DOI: 10.1002/Anie.200805396  0.681
2009 Zhao Y, Schiro PG, Kuo JS, Ng L, Chiu DT. Method for the accurate preparation of cell-spiking standards. Analytical Chemistry. 81: 1285-90. PMID 19115959 DOI: 10.1021/Ac802250D  0.737
2009 Chiu DT, Mutch SA, Fujimoto B, Gadd J, Bajjalieh SM. Quantitative TIRF microscopy for counting protein copy numbers in isolated Sub-cellular structures Microscopy and Microanalysis. 15: 72-73. DOI: 10.1017/S1431927609093593  0.767
2009 Puchades M, Hurtig J, Chiu DT, Ewing AG. Multi-detection Device For Studying Neuronal Cell Networks Biophysical Journal. 96: 479a. DOI: 10.1016/J.Bpj.2008.12.2468  0.346
2009 Edgar J, Milne G, Zhao Y, Pabbati C, Lim D, Chiu D. Cover Picture: Compartmentalization of Chemically Separated Components into Droplets (Angew. Chem. Int. Ed. 15/2009) Angewandte Chemie International Edition. 48: 2615-2615. DOI: 10.1002/Anie.200990072  0.679
2009 Edgar J, Milne G, Zhao Y, Pabbati C, Lim D, Chiu D. Titelbild: Compartmentalization of Chemically Separated Components into Droplets (Angew. Chem. 15/2009) Angewandte Chemie. 121: 2653-2653. DOI: 10.1002/Ange.200990074  0.649
2008 Milne G, Jeffries GD, Chiu DT. Tunable generation of Bessel beams with a fluidic axicon. Applied Physics Letters. 92: 261101. PMID 19529839 DOI: 10.1063/1.2952833  0.671
2008 Zhao Y, Milne G, Edgar JS, Jeffries GD, McGloin D, Chiu DT. Quantitative force mapping of an optical vortex trap. Applied Physics Letters. 92: 161111-1611113. PMID 19479042 DOI: 10.1063/1.2912031  0.772
2008 Lorenz RM, Fiorini GS, Jeffries GD, Lim DS, He M, Chiu DT. Simultaneous generation of multiple aqueous droplets in a microfluidic device. Analytica Chimica Acta. 630: 124-30. PMID 19012823 DOI: 10.1016/J.Aca.2008.10.009  0.793
2008 Allen PB, Sgro AE, Chao DL, Doepker BE, Scott Edgar J, Shen K, Chiu DT. Single-synapse ablation and long-term imaging in live C. elegans. Journal of Neuroscience Methods. 173: 20-6. PMID 18579213 DOI: 10.1016/J.Jneumeth.2008.05.007  0.732
2008 Gadd JC, Kuyper CL, Fujimoto BS, Allen RW, Chiu DT. Sizing subcellular organelles and nanoparticles confined within aqueous droplets. Analytical Chemistry. 80: 3450-7. PMID 18363409 DOI: 10.1021/Ac8000385  0.795
2007 Zhao Y, Fujimoto BS, Jeffries GD, Schiro PG, Chiu DT. Optical gradient flow focusing. Optics Express. 15: 6167-76. PMID 19546921 DOI: 10.1364/Oe.15.006167  0.783
2007 Zhao Y, Edgar JS, Jeffries GD, McGloin D, Chiu DT. Spin-to-orbital angular momentum conversion in a strongly focused optical beam. Physical Review Letters. 99: 073901. PMID 17930896 DOI: 10.1103/Physrevlett.99.073901  0.766
2007 Allen PB, Doepker BR, Chiu DT. Fourier transform capillary electrophoresis with laminar-flow gated pressure injection. Analytical Chemistry. 79: 6807-15. PMID 17676758 DOI: 10.1021/Ac0710026  0.304
2007 Pan T, Fiorini GS, Chiu DT, Woolley AT. In-channel atom-transfer radical polymerization of thermoset polyester microfluidic devices for bioanalytical applications. Electrophoresis. 28: 2904-11. PMID 17640094 DOI: 10.1002/Elps.200600817  0.786
2007 Fiorini GS, Yim M, Jeffries GD, Schiro PG, Mutch SA, Lorenz RM, Chiu DT. Fabrication improvements for thermoset polyester (TPE) microfluidic devices. Lab On a Chip. 7: 923-6. PMID 17594014 DOI: 10.1039/B702548C  0.778
2007 Schiro PG, Kuyper CL, Chiu DT. Continuous-flow single-molecule CE with high detection efficiency. Electrophoresis. 28: 2430-8. PMID 17577880 DOI: 10.1002/Elps.200600730  0.801
2007 Sgro AE, Allen PB, Chiu DT. Thermoelectric manipulation of aqueous droplets in microfluidic devices. Analytical Chemistry. 79: 4845-51. PMID 17542555 DOI: 10.1021/Ac062458A  0.75
2007 Jeffries GD, Kuo JS, Chiu DT. Controlled shrinkage and re-expansion of a single aqueous droplet inside an optical vortex trap. The Journal of Physical Chemistry. B. 111: 2806-12. PMID 17388431 DOI: 10.1021/Jp068902V  0.693
2007 Jeffries GD, Edgar JS, Zhao Y, Shelby JP, Fong C, Chiu DT. Using polarization-shaped optical vortex traps for single-cell nanosurgery. Nano Letters. 7: 415-20. PMID 17298009 DOI: 10.1021/Nl0626784  0.784
2007 Mutch SA, Fujimoto BS, Kuyper CL, Kuo JS, Bajjalieh SM, Chiu DT. Deconvolving single-molecule intensity distributions for quantitative microscopy measurements. Biophysical Journal. 92: 2926-43. PMID 17259276 DOI: 10.1529/Biophysj.106.101428  0.787
2007 Jeffries GD, Kuo JS, Chiu DT. Dynamic modulation of chemical concentration in an aqueous droplet. Angewandte Chemie (International Ed. in English). 46: 1326-8. PMID 17203495 DOI: 10.1002/Anie.200603072  0.669
2007 Lorenz RM, Edgar JS, Jeffries GD, Zhao Y, McGloin D, Chiu DT. Vortex-trap-induced fusion of femtoliter-volume aqueous droplets. Analytical Chemistry. 79: 224-8. PMID 17194143 DOI: 10.1021/Ac061586W  0.785
2007 McGloin D, Buchanan J, Burnham DR, Lorenz RM, Edgar JS, Jeffries GDM, Zhao Y, Chiu DT. Controlled fusion of femtoliter-volume aqueous droplets using holographic optical tweezers Conference On Lasers and Electro-Optics Europe - Technical Digest. DOI: 10.1109/CLEOE-IQEC.2007.4386646  0.65
2007 Cohen DE, Benedict JB, Morlan B, Chiu DT, Kahr B. Dyeing polymorphs: The MALDI host 2,5-dihydroxybenzoic acid Crystal Growth and Design. 7: 492-495. DOI: 10.1021/Cg060887W  0.536
2007 Fiorini GS, Chiu DT. Nanoscale chemical analysis of individual subcellular compartments Chemical Analysis. 172: 119-140. DOI: 10.1002/9780470119501.ch6  0.773
2006 Kuyper CL, Fujimoto BS, Zhao Y, Schiro PG, Chiu DT. Accurate sizing of nanoparticles using confocal correlation spectroscopy. The Journal of Physical Chemistry. B. 110: 24433-41. PMID 17134198 DOI: 10.1021/Jp064865W  0.789
2006 Edgar JS, Pabbati CP, Lorenz RM, He M, Fiorini GS, Chiu DT. Capillary electrophoresis separation in the presence of an immiscible boundary for droplet analysis. Analytical Chemistry. 78: 6948-54. PMID 17007519 DOI: 10.1021/Ac0613131  0.79
2006 Lorenz RM, Edgar JS, Jeffries GD, Chiu DT. Microfluidic and optical systems for the on-demand generation and manipulation of single femtoliter-volume aqueous droplets. Analytical Chemistry. 78: 6433-9. PMID 16970318 DOI: 10.1021/Ac060748L  0.789
2006 Kuyper CL, Kuo JS, Mutch SA, Chiu DT. Proton permeation into single vesicles occurs via a sequential two-step mechanism and is heterogeneous. Journal of the American Chemical Society. 128: 3233-40. PMID 16522104 DOI: 10.1021/Ja057349C  0.789
2006 Kuyper CL, Budzinski KL, Lorenz RM, Chiu DT. Real-time sizing of nanoparticles in microfluidic channels using confocal correlation spectroscopy. Journal of the American Chemical Society. 128: 730-1. PMID 16417357 DOI: 10.1021/Ja0569252  0.787
2006 Chiu DT, Zare RN. Optical Detection and Manipulation of Single Molecules in Room-Temperature Solutions Chemistry: a European Journal. 3: 335-339. DOI: 10.1002/Chem.19970030304  0.463
2005 Sun B, Mutch SA, Lorenz RM, Chiu DT. Layered polyelectrolyte-silica coating for nanocapsules. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 10763-9. PMID 16262349 DOI: 10.1021/La0513297  0.772
2005 Sun B, Chiu DT. Determination of the encapsulation efficiency of individual vesicles using single-vesicle photolysis and confocal single-molecule detection. Analytical Chemistry. 77: 2770-6. PMID 15859592 DOI: 10.1021/Ac048439N  0.547
2005 Shelby JP, Edgar JS, Chiu DT. Monitoring cell survival after extraction of a single subcellular organelle using optical trapping and pulsed-nitrogen laser ablation. Photochemistry and Photobiology. 81: 994-1001. PMID 15850426 DOI: 10.1562/2005-02-02-Ra-431R1.1  0.776
2005 Fiorini GS, Chiu DT. Disposable microfluidic devices: fabrication, function, and application. Biotechniques. 38: 429-46. PMID 15786809 DOI: 10.2144/05383Rv02  0.796
2005 He M, Edgar JS, Jeffries GD, Lorenz RM, Shelby JP, Chiu DT. Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets. Analytical Chemistry. 77: 1539-44. PMID 15762555 DOI: 10.1021/Ac0480850  0.789
2005 Kuyper CL, Jeffries GDM, Lorenz RM, Chiu DT. Single-Molecule Detection and Manipulation in Nanotechnology and Biology Nanofabrication Towards Biomedical Applications: Techniques, Tools, Applications, and Impact. 197-225. DOI: 10.1002/3527603476.ch8  0.731
2005 Shelby JP, Lim DSW, Kuo JS, Chiu DT. The generation, characterization, and application of microvortices in microfluidic systems Proceedings of the 3rd International Conference On Microchannels and Minichannels, 2005. 203-210.  0.76
2004 Sun B, Chiu DT. Synthesis, loading, and application of individual nanocapsules for probing single-cell signaling. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 4614-20. PMID 15969173 DOI: 10.1021/La0364340  0.546
2004 Kuo JS, Kuyper CL, Allen PB, Fiorini GS, Chiu DT. High-power blue/UV light-emitting diodes as excitation sources for sensitive detection. Electrophoresis. 25: 3796-804. PMID 15565689 DOI: 10.1002/Elps.200406118  0.796
2004 Sun B, Lim DS, Kuo JS, Kuyper CL, Chiu DT. Fast initiation of chemical reactions with laser-induced breakdown of a nanoscale partition. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 9437-40. PMID 15491172 DOI: 10.1021/La048444M  0.775
2004 Fiorini GS, Lorenz RM, Kuo JS, Chiu DT. Rapid prototyping of thermoset polyester microfluidic devices. Analytical Chemistry. 76: 4697-704. PMID 15307779 DOI: 10.1021/Ac0498922  0.784
2004 Shelby JP, Chiu DT. Controlled rotation of biological micro- and nano-particles in microvortices. Lab On a Chip. 4: 168-70. PMID 15159772 DOI: 10.1039/B402479F  0.779
2004 Shelby JP, Mutch SA, Chiu DT. Direct manipulation and observation of the rotational motion of single optically trapped microparticles and biological cells in microvortices. Analytical Chemistry. 76: 2492-7. PMID 15117188 DOI: 10.1021/Ac035531V  0.788
2004 Lorenz RM, Kuyper CL, Allen PB, Lee LP, Chiu DT. Direct laser writing on electrolessly deposited thin metal films for applications in micro- and nanofluidics Langmuir. 20: 1833-1837. DOI: 10.1021/La036047Q  0.734
2003 Fiorini GS, Jeffries GD, Lim DS, Kuyper CL, Chiu DT. Fabrication of thermoset polyester microfluidic devices and embossing masters using rapid prototyped polydimethylsiloxane molds. Lab On a Chip. 3: 158-63. PMID 15100767 DOI: 10.1039/B305074M  0.776
2003 Shelby JP, White J, Ganesan K, Rathod PK, Chiu DT. A microfluidic model for single-cell capillary obstruction by Plasmodium falciparum-infected erythrocytes. Proceedings of the National Academy of Sciences of the United States of America. 100: 14618-22. PMID 14638939 DOI: 10.1073/Pnas.2433968100  0.779
2003 Shelby JP, Lim DS, Kuo JS, Chiu DT. Microfluidic systems: high radial acceleration in microvortices. Nature. 425: 38. PMID 12955132 DOI: 10.1038/425038A  0.778
2003 Lundqvist A, Chiu DT, Orwar O. Electrophoretic separation and confocal laser-induced fluorescence detection at ultralow concentrations in constricted fused-silica capillaries. Electrophoresis. 24: 1737-44. PMID 12783450 DOI: 10.1002/Elps.200305429  0.347
2003 Allen PB, Rodriguez I, Kuyper CL, Lorenz RM, Spicar-Mihalic P, Kuo JS, Chiu DT. Selective electroless and electrolytic deposition of metal for applications in microfluidics: fabrication of a microthermocouple. Analytical Chemistry. 75: 1578-83. PMID 12705588 DOI: 10.1021/Ac020498I  0.74
2003 Shelby JP, Chiu DT. Mapping fast flows over micrometer-length scales using flow-tagging velocimetry and single-molecule detection. Analytical Chemistry. 75: 1387-92. PMID 12659200 DOI: 10.1021/Ac026275+  0.793
2003 Sun B, Chiu DT. Spatially and temporally resolved delivery of stimuli to single cells. Journal of the American Chemical Society. 125: 3702-3. PMID 12656592 DOI: 10.1021/Ja029942P  0.527
2003 Wu H, Odom TW, Chiu DT, Whitesides GM. Fabrication of complex three-dimensional microchannel systems in PDMS. Journal of the American Chemical Society. 125: 554-9. PMID 12517171 DOI: 10.1021/Ja021045Y  0.618
2003 Sun B, Chiu DT. Functional Mapping of Cell Surface Proteins with Localized Stimulation of Single Cells Proceedings of Spie - the International Society For Optical Engineering. 5222: 118-125. DOI: 10.1117/12.506906  0.483
2003 Lim DSW, Shelby JP, Kuo JS, Chiu DT. Dynamic formation of ring-shaped patterns of colloidal particles in microfluidic systems Applied Physics Letters. 83: 1145-1147. DOI: 10.1063/1.1600532  0.78
2003 Kuyper CL, Brewood GP, Chiu DT. Initiating Conformation Transitions of Individual YOYO-Intercalated DNA Molecules with Optical Trapping Nano Letters. 3: 1387-1389. DOI: 10.1021/Nl0345668  0.743
2003 Rodriguez I, Spicar-Mihalic P, Kuyper CL, Fiorini GS, Chiu DT. Rapid prototyping of glass microchannels Analytica Chimica Acta. 496: 205-215. DOI: 10.1016/S0003-2670(03)01000-6  0.771
2002 Kuyper CL, Chiu DT. Optical Trapping: A Versatile Technique for Biomanipulation Applied Spectroscopy. 56: 300A-312A. DOI: 10.1366/00037020260377652  0.753
2002 Seo J, Kuyper CL, Chiu DT, Lee LP. Biophotonic MEMS for single molecule detection and manipulation 2nd Annual International Ieee-Embs Special Topic Conference On Microtechnologies in Medicine and Biology - Proceedings. 363-368. DOI: 10.1109/MMB.2002.1002347  0.756
2002 Jeon NL, Chiu DT, Wargo CJ, Wu H, Choi IS, Anderson JR, Whitesides GM. Design and fabrication of integrated passive valves and pumps for flexible polymer 3-dimensional microfluidic systems Biomedical Microdevices. 4: 117-121. DOI: 10.1023/A:1014683114796  0.729
2001 Ismagilov RF, Rosmarin TD, Kenis JA, Chiu DT, Zhang W, Stone HA, Whitesides GM. Pressure-driven laminar flow in tangential microchannels: an elastomeric microfluidic switch. Analytical Chemistry. 73: 4682-7. PMID 11605847 DOI: 10.1021/Ac010374Q  0.592
2001 Chabinyc ML, Chiu DT, McDonald JC, Stroock AD, Christian JF, Karger AM, Whitesides GM. An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications. Analytical Chemistry. 73: 4491-8. PMID 11575798 DOI: 10.1021/Ac010423Z  0.762
2001 Wilson CF, Simpson GJ, Chiu DT, Strömberg A, Orwar O, Rodriguez N, Zare RN. Nanoengineered structures for holding and manipulating liposomes and cells. Analytical Chemistry. 73: 787-91. PMID 11248893 DOI: 10.1021/Ac001020M  0.793
2001 Chiu DT, Pezzoli E, Wu H, Stroock AD, Whitesides GM. Using three-dimensional microfluidic networks for solving computationally hard problems. Proceedings of the National Academy of Sciences of the United States of America. 98: 2961-6. PMID 11248014 DOI: 10.1073/Pnas.061014198  0.664
2001 Strömberg A, Karlsson A, Ryttsén F, Davidson M, Chiu DT, Orwar O. Microfluidic device for combinatorial fusion of liposomes and cells. Analytical Chemistry. 73: 126-30. PMID 11195496 DOI: 10.1021/Ac000528M  0.333
2001 Stroock AD, Weck M, Chiu DT, Huck WTS, Kenis PJA, Ismagilov RF, Whitesides GM. Erratum: Patterning Electro-osmotic Flow with Patterned Surface Charge [Phys. Rev. Lett. 84, 3314 (2000)] Physical Review Letters. 86: 6050-6050. DOI: 10.1103/Physrevlett.86.6050  0.741
2001 Dertinger SKW, Chiu DT, Jeon NL, Whitesides GM. Generation of Gradients Having Complex Shapes Using Microfluidic Networks Analytical Chemistry. 73: 1240-1246. DOI: 10.1021/Ac001132D  0.411
2000 Ryttsén F, Farre C, Brennan C, Weber SG, Nolkrantz K, Jardemark K, Chiu DT, Orwar O. Characterization of single-cell electroporation by using patch-clamp and fluorescence microscopy. Biophysical Journal. 79: 1993-2001. PMID 11023903 DOI: 10.1016/S0006-3495(00)76447-2  0.313
2000 Stroock AD, Weck M, Chiu DT, Huck WT, Kenis PJ, Ismagilov RF, Whitesides GM. Patterning electro-osmotic flow with patterned surface charge. Physical Review Letters. 84: 3314-7. PMID 11019078 DOI: 10.1103/Physrevlett.84.3314  0.767
2000 Anderson JR, Chiu DT, Jackman RJ, Cherniavskaya O, McDonald JC, Wu H, Whitesides SH, Whitesides GM. Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping. Analytical Chemistry. 72: 3158-64. PMID 10939381 DOI: 10.1021/Ac9912294  0.698
2000 Chiu DT, Jeon NL, Huang S, Kane RS, Wargo CJ, Choi IS, Ingber DE, Whitesides GM. Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proceedings of the National Academy of Sciences of the United States of America. 97: 2408-13. PMID 10681460 DOI: 10.1073/Pnas.040562297  0.722
2000 McDonald JC, Duffy DC, Anderson JR, Chiu DT, Wu H, Schueller OJ, Whitesides GM. Fabrication of microfluidic systems in poly(dimethylsiloxane). Electrophoresis. 21: 27-40. PMID 10634468 DOI: 10.1002/(Sici)1522-2683(20000101)21:1<27::Aid-Elps27>3.0.Co;2-C  0.705
2000 Strömberg A, Ryttsén F, Chiu DT, Davidson M, Eriksson PS, Wilson CF, Orwar O, Zare RN. Manipulating the genetic identity and biochemical surface properties of individual cells with electric-field-induced fusion. Proceedings of the National Academy of Sciences of the United States of America. 97: 7-11. PMID 10618361 DOI: 10.1073/Pnas.97.1.7  0.653
2000 Jeon NL, Dertinger SKW, Chiu DT, Choi IS, Stroock AD, Whitesides GM. Generation of solution and surface gradients using microfluidic systems Langmuir. 16: 8311-8316. DOI: 10.1021/La000600B  0.703
1999 Chiu DT, Wilson CF, Ryttsén F, Strömberg A, Farre C, Karlsson A, Nordholm S, Gaggar A, Modi BP, Moscho A, Garza-López RA, Orwar O, Zare RN. Chemical transformations in individual ultrasmall biomimetic containers. Science (New York, N.Y.). 283: 1892-5. PMID 10082457 DOI: 10.1126/Science.283.5409.1892  0.666
1999 Chiu DT, Wilson CF, Karlsson A, Danielsson A, Lundqvist A, Strömberg A, Ryttsén F, Davidson M, Nordholm S, Orwar O, Zare RN. Manipulating the biochemical nanoenvironment around single molecules contained within vesicles Chemical Physics. 247: 133-139. DOI: 10.1016/S0301-0104(99)00154-8  0.615
1998 Lillard SJ, Chiu DT, Scheller RH, Zare RN, Rodríguez-Cruz SE, Williams ER, Orwar O, Sandberg M, Lundqvist JA. Separation and characterization of amines from individual atrial gland vesicles of Aplysia californica. Analytical Chemistry. 70: 3517-24. PMID 9737203 DOI: 10.1021/ac980462j  0.355
1998 Chiu DT, Zare RN. Assaying for peptides in individual Aplysia neurons with mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 95: 3338-40. PMID 9520363 DOI: 10.1073/Pnas.95.7.3338  0.476
1998 Chiu DT, Lillard SJ, Scheller RH, Zare RN, Rodriguez-Cruz SE, Williams ER, Orwar O, Sandberg M, Lundqvist JA. Probing single secretory vesicles with capillary electrophoresis. Science (New York, N.Y.). 279: 1190-3. PMID 9469805 DOI: 10.1126/Science.279.5354.1190  0.497
1997 Chiu DT, Hsiao A, Gaggar A, Garza-López RA, Orwar O, Zare RN. Injection of ultrasmall samples and single molecules into tapered capillaries. Analytical Chemistry. 69: 1801-7. PMID 9164157 DOI: 10.1021/Ac961226G  0.416
1996 Moscho A, Orwar O, Chiu DT, Modi BP, Zare RN. Rapid preparation of giant unilamellar vesicles. Proceedings of the National Academy of Sciences of the United States of America. 93: 11443-7. PMID 8876154 DOI: 10.1073/Pnas.93.21.11443  0.41
1996 Chiu DT, Zare RN. Biased Diffusion, Optical Trapping, and Manipulation of Single Molecules in Solution Journal of the American Chemical Society. 118: 6512-6513. DOI: 10.1021/Ja960978P  0.472
1995 Nie S, Chiu DT, Zare RN. Real-Time Detection of Single Molecules in Solution by Confocal Fluorescence Microscopy Analytical Chemistry. 67: 2849-2857. DOI: 10.1021/Ac00113A019  0.605
1994 Nie S, Chiu DT, Zare RN. Probing individual molecules with confocal fluorescence microscopy. Science (New York, N.Y.). 266: 1018-21. PMID 7973650 DOI: 10.1126/Science.7973650  0.602
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