Jane A. Little, M.D.

Affiliations: 
1990-2000 University of Minnesota, Twin Cities, Minneapolis, MN 
 2001-2006 National Institutes of Health, Bethesda, MD 
 2006-2011 Albert Einstein College of Medicine, New York, New York, United States 
 2011-2018 Case Western Reserve University, Cleveland Heights, OH, United States 
 2018- University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
hematology
Website:
https://www.med.unc.edu/medicine/directory/jane-little/
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"Jane A. Little"
Bio:

https://www.ashclinicalnews.org/spotlight/pulling-back-the-curtain/pulling-back-curtain-jane-little-md/

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Publications

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Farrell AT, Panepinto J, Desai AA, et al. (2019) End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Advances. 3: 4002-4020
Nouraie M, Little JA, Hildesheim M, et al. (2019) Validation of a composite vascular high risk profile for adult patients with sickle cell disease. American Journal of Hematology
Sinha AA, Adusumilli T, Cohen HW, et al. (2019) Splenectomy is not associated with a higher tricuspid regurgitant jet velocity in people with sickle cell anemia. Pediatric Blood & Cancer. e27928
Advani A, Cooper BW, Visconte V, et al. (2019) A Phase 1/2 Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib for Relapsed/ Refractory Acute Myeloid Leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Hambley BC, Abdul Rahman R, Reback M, et al. (2018) Intracardiac or intrapulmonary shunts were present in at least 35% of adults with homozygous sickle cell disease followed in an outpatient clinic. Haematologica
Rotz SJ, O'Riordan MA, Kim C, et al. (2016) Nocturnal hemoglobin desaturation is associated with reticulocytosis in adults with sickle cell disease and is independent of obstructive sleep apnea. American Journal of Hematology
Alapan Y, Kim C, Adhikari A, et al. (2016) Sickle cell disease biochip: a functional red blood cell adhesion assay for monitoring sickle cell disease. Translational Research : the Journal of Laboratory and Clinical Medicine
Drawz P, Ayyappan S, Nouraie M, et al. (2016) Kidney Disease among Patients with Sickle Cell Disease, Hemoglobin SS and SC. Clinical Journal of the American Society of Nephrology : Cjasn. 11: 207-15
Karkashon S, Raghupathy R, Bhatia H, et al. (2015) Intermediaries of branched chain amino acid metabolism induce fetal hemoglobin, and repress SOX6 and BCL11A, in definitive erythroid cells. Blood Cells, Molecules & Diseases. 55: 161-7
Rotz SJ, O'Riordan MA, Kim C, et al. (2015) Traffic Light: prognosis-based eligibility for clinical trials of hematopoietic SCT in adults with sickle cell anemia. Bone Marrow Transplantation. 50: 918-23
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