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Rolf Martin Zinkernagel - Publications

Affiliations: 
Institute of Experimental Immunology Universität Zürich, Zürich, ZH, Switzerland 
Area:
Immunology
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1996/zinkernagel-bio.html

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Year Citation  Score
2018 Zinkernagel RM. What if protective immunity is antigen-driven and not due to so-called "memory" B and T cells? Immunological Reviews. 283: 238-246. PMID 29664570 DOI: 10.1111/imr.12648  0.485
2018 Tullius SG, Kumamoto Y, Zinkernagel RM, Utku N. Anti-TIRC7 Antibody Treatment Prevents Rejection of Mice Cardiac Allografts while Immune Competency to Viral and Bacterial Antigens Remain Normal Transplantation. 102: S451. DOI: 10.1097/01.tp.0000543242.77554.84  0.502
2016 Farber DL, Netea MG, Radbruch A, Rajewsky K, Zinkernagel RM. Immunological memory: lessons from the past and a look to the future. Nature Reviews. Immunology. 16: 124-8. PMID 26831526 DOI: 10.1038/Nri.2016.13  0.396
2014 Zinkernagel R. On plasma cell longevity or brevity Expert Review of Vaccines. 13: 821-823. PMID 24909054 DOI: 10.1586/14760584.2014.924402  0.521
2014 Zinkernagel RM. On the Role of Dendritic Cells Versus Other Cells in Inducing Protective CD8+ T Cell Responses. Frontiers in Immunology. 5: 30. PMID 24575091 DOI: 10.3389/fimmu.2014.00030  0.554
2013 Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, ... ... Zinkernagel RM, et al. Reactive oxygen species delay control of lymphocytic choriomeningitis virus. Cell Death and Differentiation. 20: 649-58. PMID 23328631 DOI: 10.1038/Cdd.2012.167  0.704
2012 Zinkernagel RM. Immunological memory ≠ protective immunity. Cellular and Molecular Life Sciences : Cmls. 69: 1635-40. PMID 22481438 DOI: 10.1007/s00018-012-0972-y  0.531
2012 Zinkernagel RM. Activation or suppression of bactericidal activity of macrophages during a graft-versus-host reaction against I-A and I-J-region differences, respectively. Immunogenetics. 10: 373-82. PMID 22457929 DOI: 10.1007/BF01561587  0.326
2011 Verschoor A, Neuenhahn M, Navarini AA, Graef P, Plaumann A, Seidlmeier A, Nieswandt B, Massberg S, Zinkernagel RM, Hengartner H, Busch DH. A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3. Nature Immunology. 12: 1194-201. PMID 22037602 DOI: 10.1038/ni.2140  0.606
2010 Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, ... ... Zinkernagel RM, et al. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology (Baltimore, Md.). 52: 25-32. PMID 20578253 DOI: 10.1002/Hep.23640  0.675
2010 Navarini AA, Krzyzowska M, Lang KS, Horvath E, Hengartner H, Niemialtowski MG, Zinkernagel RM. Long-lasting immunity by early infection of maternal-antibody-protected infants. European Journal of Immunology. 40: 113-6. PMID 19877011 DOI: 10.1002/eji.200939371  0.611
2010 ZINKERNAGEL RM. ChemInform Abstract: Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens (Nobel Lecture) Cheminform. 28: no-no. DOI: 10.1002/CHIN.199750335  0.351
2009 Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proceedings of the National Academy of Sciences of the United States of America. 106: 7107-12. PMID 19351895 DOI: 10.1073/Pnas.0901162106  0.585
2009 Geuking MB, Weber J, Dewannieux M, Gorelik E, Heidmann T, Hengartner H, Zinkernagel RM, Hangartner L. Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration. Science (New York, N.Y.). 323: 393-6. PMID 19150848 DOI: 10.1126/science.1167375  0.561
2008 McCoy KD, Stoel M, Stettler R, Merky P, Fink K, Senn BM, Schaer C, Massacand J, Odermatt B, Oettgen HC, Zinkernagel RM, Bos NA, Hengartner H, Macpherson AJ, Harris NL. Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection. Cell Host & Microbe. 4: 362-73. PMID 18854240 DOI: 10.1016/j.chom.2008.08.014  0.634
2008 Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, ... ... Zinkernagel RM, et al. Aggravation of viral hepatitis by platelet-derived serotonin. Nature Medicine. 14: 756-61. PMID 18516052 DOI: 10.1038/Nm1780  0.638
2008 Kranich J, Krautler NJ, Heinen E, Polymenidou M, Bridel C, Schildknecht A, Huber C, Kosco-Vilbois MH, Zinkernagel R, Miele G, Aguzzi A. Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8 Journal of Experimental Medicine. 205: 1293-1302. PMID 18490487 DOI: 10.1084/Jem.20071019  0.487
2008 Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Höfer T, Radbruch A, Zinkernagel RM, Hengartner H. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. The Journal of Experimental Medicine. 205: 53-61. PMID 18195073 DOI: 10.1084/Jem.20071855  0.683
2008 Fink K, Zellweger R, Weber J, Manjarrez-Orduno N, Holdener M, Senn BM, Hengartner H, Zinkernagel RM, Macpherson AJ. Long-term maternal imprinting of the specific B cell repertoire by maternal antibodies. European Journal of Immunology. 38: 90-101. PMID 18081043 DOI: 10.1002/eji.200737872  0.645
2007 Zinkernagel RM. Science and sensibility: an interview with Professor Rolf M. Zinkernagel, Nobel Prize Winner for Medicine 1996. Interview by Hrishikesh Satish Kulkarni and Ajit H. Goenka. Medgenmed : Medscape General Medicine. 9: 28. PMID 18311378  0.187
2007 Lang KS, Hegazy AN, Lang PA, Eschli B, Löhning M, Hengartner H, Zinkernagel RM, Recher M. "Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses. Plos One. 2: e1162. PMID 18000535 DOI: 10.1371/Journal.Pone.0001162  0.706
2007 Lötscher M, Recher M, Lang KS, Navarini A, Hunziker L, Santimaria R, Glatzel M, Schwarz P, Böni J, Zinkernagel RM. Induced prion protein controls immune-activated retroviruses in the mouse spleen. Plos One. 2: e1158. PMID 17987132 DOI: 10.1371/Journal.Pone.0001158  0.435
2007 Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, ... ... Zinkernagel RM, et al. Extralymphatic virus sanctuaries as a consequence of potent T-cell activation. Nature Medicine. 13: 1316-23. PMID 17982463 DOI: 10.1038/Nm1670  0.73
2007 Fink K, Manjarrez-Orduño N, Schildknecht A, Weber J, Senn BM, Zinkernagel RM, Hengartner H. B cell activation state-governed formation of germinal centers following viral infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 5877-85. PMID 17947661 DOI: 10.4049/Jimmunol.179.9.5877  0.673
2007 Eschli B, Zellweger RM, Wepf A, Lang KS, Quirin K, Weber J, Zinkernagel RM, Hengartner H. Early antibodies specific for the neutralizing epitope on the receptor binding subunit of the lymphocytic choriomeningitis virus glycoprotein fail to neutralize the virus. Journal of Virology. 81: 11650-7. PMID 17699567 DOI: 10.1128/JVI.00955-07  0.66
2007 Freigang S, Eschli B, Harris N, Geuking M, Quirin K, Schrempf S, Zellweger R, Weber J, Hengartner H, Zinkernagel RM. A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses. Proceedings of the National Academy of Sciences of the United States of America. 104: 13426-31. PMID 17686978 DOI: 10.1073/pnas.0704423104  0.681
2007 Lang KS, Navarini AA, Recher M, Lang PA, Heikenwalder M, Stecher B, Bergthaler A, Odermatt B, Akira S, Honda K, Hengartner H, Zinkernagel RM. MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus. European Journal of Immunology. 37: 2434-40. PMID 17668900 DOI: 10.1002/Eji.200737310  0.645
2007 Pochanke V, Koller S, Dayer R, Hatak S, Ludewig B, Zinkernagel RM, Hengartner H, McCoy KD. Identification and characterization of a novel antigen from the nematode Nippostrongylus brasiliensis recognized by specific IgE. European Journal of Immunology. 37: 1275-84. PMID 17429848 DOI: 10.1002/eji.200737135  0.638
2007 Zinkernagel R. On observing and analyzing disease versus signals Nature Immunology. 8: 8-10. PMID 17179962 DOI: 10.1038/ni0107-8  0.416
2007 Brent L, Cohen IR, Doherty PC, Feldmann M, Matzinger P, Ghost Lab, Holgate ST, Lachmann P, Mitchison NA, Nossal G, Rose NR, Zinkernagel R. Crystal-ball gazing--the future of immunological research viewed from the cutting edge. Clinical and Experimental Immunology. 147: 1-10. PMID 17177957 DOI: 10.1111/J.1365-2249.2006.03234.X  0.563
2007 Zinkernagel R. Editorial European Journal of Immunology. 37: 1-3. DOI: 10.1002/eji.200690051  0.277
2007 Kulkarni HS, Goenka AH, Zinkernagel RM. Science and sensibility: An interview with professor Rolf M. Zinkernagel, Novel Prize winner for medicine 1996 Medgenmed Medscape General Medicine. 9.  0.171
2006 Zellweger RM, Hangartner L, Weber J, Zinkernagel RM, Hengartner H. Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection. European Journal of Immunology. 36: 3175-85. PMID 17125146 DOI: 10.1002/eji.200636087  0.688
2006 Harris NL, Spoerri I, Schopfer JF, Nembrini C, Merky P, Massacand J, Urban JF, Lamarre A, Burki K, Odermatt B, Zinkernagel RM, Macpherson AJ. Mechanisms of neonatal mucosal antibody protection. Journal of Immunology (Baltimore, Md. : 1950). 177: 6256-62. PMID 17056555 DOI: 10.4049/Jimmunol.177.9.6256  0.419
2006 Navarini AA, Recher M, Lang KS, Georgiev P, Meury S, Bergthaler A, Flatz L, Bille J, Landmann R, Odermatt B, Hengartner H, Zinkernagel RM. Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 15535-9. PMID 17030789 DOI: 10.1073/pnas.0607325103  0.622
2006 Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM. Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC. Proceedings of the National Academy of Sciences of the United States of America. 103: 14435-40. PMID 16983067 DOI: 10.1073/pnas.0606707103  0.681
2006 Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM. Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling. The Journal of Clinical Investigation. 116: 2456-63. PMID 16955143 DOI: 10.1172/JCI28349  0.621
2006 Pochanke V, Hatak S, Hengartner H, Zinkernagel RM, McCoy KD. Induction of IgE and allergic-type responses in fur mite-infested mice. European Journal of Immunology. 36: 2434-45. PMID 16909433 DOI: 10.1002/eji.200635949  0.643
2006 Hangartner L, Zellweger RM, Giobbi M, Weber J, Eschli B, McCoy KD, Harris N, Recher M, Zinkernagel RM, Hengartner H. Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread. The Journal of Experimental Medicine. 203: 2033-42. PMID 16880253 DOI: 10.1084/jem.20051557  0.646
2006 Junt T, Tumanov AV, Harris N, Heikenwalder M, Zeller N, Kuprash DV, Aguzzi A, Ludewig B, Nedospasov SA, Zinkernagel RM. Expression of lymphotoxin beta governs immunity at two distinct levels. European Journal of Immunology. 36: 2061-75. PMID 16841297 DOI: 10.1002/Eji.200626255  0.603
2006 Zinkernagel RM, Hengartner H. Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'. Immunological Reviews. 211: 310-9. PMID 16824138 DOI: 10.1111/j.0105-2896.2006.00402.x  0.678
2006 Fink K, Lang KS, Manjarrez-Orduno N, Junt T, Senn BM, Holdener M, Akira S, Zinkernagel RM, Hengartner H. Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses. European Journal of Immunology. 36: 2094-105. PMID 16810635 DOI: 10.1002/eji.200635993  0.674
2006 Eschli B, Quirin K, Wepf A, Weber J, Zinkernagel R, Hengartner H. Identification of an N-terminal trimeric coiled-coil core within arenavirus glycoprotein 2 permits assignment to class I viral fusion proteins. Journal of Virology. 80: 5897-907. PMID 16731928 DOI: 10.1128/JVI.00008-06  0.554
2006 Merkler D, Horvath E, Bruck W, Zinkernagel RM, Del la Torre JC, Pinschewer DD. "Viral déjà vu" elicits organ-specific immune disease independent of reactivity to self. The Journal of Clinical Investigation. 116: 1254-63. PMID 16604192 DOI: 10.1172/JCI27372  0.555
2006 McCoy KD, Harris NL, Diener P, Hatak S, Odermatt B, Hangartner L, Senn BM, Marsland BJ, Geuking MB, Hengartner H, Macpherson AJ, Zinkernagel RM. Natural IgE production in the absence of MHC Class II cognate help. Immunity. 24: 329-39. PMID 16546101 DOI: 10.1016/j.immuni.2006.01.013  0.664
2006 Hangartner L, Zinkernagel RM, Hengartner H. Antiviral antibody responses: the two extremes of a wide spectrum. Nature Reviews. Immunology. 6: 231-43. PMID 16498452 DOI: 10.1038/nri1783  0.649
2006 Bonilla WV, Geuking MB, Aichele P, Ludewig B, Hengartner H, Zinkernagel RM. Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoire. The Journal of Clinical Investigation. 116: 156-62. PMID 16395404 DOI: 10.1172/JCI26565  0.67
2006 Zinkernagel RM, Hengartner H. Infections, Immunity, and Autoimmunity The Autoimmune Diseases. 289-295. DOI: 10.1016/B978-012595961-2/50025-1  0.567
2006 Ng Mah Lee M, Rice C, Fairlie D, Zinkernagel R, Young P, Neyts J, Hibberd M, Holmes E, Heinz FX, Stephenson J. Final discussion Novartis Foundation Symposium. 277: 251-253.  0.185
2006 Canard B, Stephenson J, Hombach J, Keller T, Halstead S, Heinz FX, Evans TG, Gubler DJ, Farrar J, Zinkernagel R. Discussion Novartis Foundation Symposium. 277: 201-205.  0.182
2005 Junt T, Fink K, Förster R, Senn B, Lipp M, Muramatsu M, Zinkernagel RM, Ludewig B, Hengartner H. CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses. Journal of Immunology (Baltimore, Md. : 1950). 175: 7109-16. PMID 16301613 DOI: 10.4049/Jimmunol.175.11.7109  0.66
2005 Lang KS, Recher M, Navarini AA, Freigang S, Harris NL, van den Broek M, Odermatt B, Hengartner H, Zinkernagel RM. Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology. Journal of Immunology (Baltimore, Md. : 1950). 175: 5524-31. PMID 16210661 DOI: 10.4049/Jimmunol.175.8.5524  0.659
2005 Zinkernagel R, Hengartner H. Responses to Cohn's discussion on the Zinkernagel-Hengartner 'Credo 2004'. Scandinavian Journal of Immunology. 62: 195-201. PMID 16179005 DOI: 10.1111/j.1365-3083.2005.01628.x  0.461
2005 Probst HC, Tschannen K, Odermatt B, Schwendener R, Zinkernagel RM, Van Den Broek M. Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells. Clinical and Experimental Immunology. 141: 398-404. PMID 16045728 DOI: 10.1111/j.1365-2249.2005.02868.x  0.429
2005 Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM. Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation. European Journal of Immunology. 35: 738-45. PMID 15724249 DOI: 10.1002/eji.200425828  0.694
2005 Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nature Medicine. 11: 138-45. PMID 15654326 DOI: 10.1038/nm1176  0.675
2005 Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM. Erratum: Corrigendum: Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease Nature Medicine. 11: 1256-1256. DOI: 10.1038/NM1105-1256  0.622
2005 Zinkernagel RM. Immunology and immunity against infection: General rules Journal of Computational and Applied Mathematics. 184: 4-9. DOI: 10.1016/j.cam.2005.02.005  0.614
2005 Zinkernagel R. Dear readers and authors of the European Journal of Immunology European Journal of Immunology. 35: 2015. DOI: 10.1002/eji.255590575  0.32
2004 Pinschewer DD, Perez M, Jeetendra E, Bächi T, Horvath E, Hengartner H, Whitt MA, de la Torre JC, Zinkernagel RM. Kinetics of protective antibodies are determined by the viral surface antigen. The Journal of Clinical Investigation. 114: 988-93. PMID 15467838 DOI: 10.1172/Jci200422374  0.663
2004 Recher M, Lang KS, Hunziker L, Freigang S, Eschli B, Harris NL, Navarini A, Senn BM, Fink K, Lötscher M, Hangartner L, Zellweger R, Hersberger M, Theocharides A, Hengartner H, ... Zinkernagel RM, et al. Deliberate removal of T cell help improves virus-neutralizing antibody production. Nature Immunology. 5: 934-42. PMID 15300247 DOI: 10.1038/ni1102  0.731
2004 Zinkernagel RM. On 'reactivity' versus 'tolerance'. Immunology and Cell Biology. 82: 343-52. PMID 15283843 DOI: 10.1111/j.0818-9641.2004.01255.x  0.495
2004 Zinkernagel RM, Hengartner H. On immunity against infections and vaccines: credo 2004. Scandinavian Journal of Immunology. 60: 9-13. PMID 15238068 DOI: 10.1111/j.0300-9475.2004.01460.x  0.713
2004 Blais ME, Gérard G, Martinic MM, Roy-Proulx G, Zinkernagel RM, Perreault C. Do thymically and strictly extrathymically developing T cells generate similar immune responses? Blood. 103: 3102-10. PMID 15070691 DOI: 10.1182/Blood-2003-09-3311  0.599
2004 Martinic MM, Rocha B, McCoy KD, Hengartner H, Zinkernagel RM. Role of TCR-restricting MHC density and thymic environment on selection and survival of cells expressing low-affinity T cell receptors. European Journal of Immunology. 34: 1041-9. PMID 15048714 DOI: 10.1002/eji.200424920  0.614
2004 Zinkernagel RM. The challenges of an HIV vaccine enterprise. Science (New York, N.Y.). 303: 1294-7; author reply. PMID 14988536 DOI: 10.1126/science.303.5662.1294  0.324
2004 Bachmann MF, Hunziker L, Zinkernagel RM, Storni T, Kopf M. Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key. European Journal of Immunology. 34: 317-26. PMID 14768036 DOI: 10.1002/eji.200324717  0.574
2004 Heikenwalder M, Polymenidou M, Junt T, Sigurdson C, Wagner H, Akira S, Zinkernagel R, Aguzzi A. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration Nature Medicine. 10: 187-192. PMID 14745443 DOI: 10.1038/Nm987  0.484
2003 Planz O, Seiler P, Hengartner H, Zinkernagel RM. Specific cytotoxic T cells eliminate cells producing neutralizing antibodies. Nature. 426: 474. PMID 14647387 DOI: 10.1038/nature02146  0.707
2003 Freigang S, Egger D, Bienz K, Hengartner H, Zinkernagel RM. Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming. Proceedings of the National Academy of Sciences of the United States of America. 100: 13477-82. PMID 14595029 DOI: 10.1073/pnas.1835685100  0.684
2003 Hangartner L, Senn BM, Ledermann B, Kalinke U, Seiler P, Bucher E, Zellweger RM, Fink K, Odermatt B, Bürki K, Zinkernagel RM, Hengartner H. Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies. Proceedings of the National Academy of Sciences of the United States of America. 100: 12883-8. PMID 14569006 DOI: 10.1073/Pnas.2135542100  0.708
2003 Silverstein AM, Rose NR, Hunziker L, Recher M, Macpherson AJ, Hengartner H, Zinkernagel RM. On the implications of polyclonal B cell activation (multiple letters) Nature Immunology. 4: 931-932. PMID 14515119 DOI: 10.1038/Ni1003-931  0.538
2003 Kadry Z, Mullhaupt B, Renner EL, Bauerfeind P, Schanz U, Pestalozzi BC, Studer G, Zinkernagel R, Clavien PA. Living donor liver transplantation and tolerance: A potential strategy in cholangiocarcinoma Transplantation. 76: 1003-1006. PMID 14508370 DOI: 10.1097/01.TP.0000083981.82522.13  0.33
2003 Hunziker L, Ciurea A, Recher M, Hengartner H, Zinkernagel RM. Public versus personal serotypes of a viral quasispecies. Proceedings of the National Academy of Sciences of the United States of America. 100: 6015-20. PMID 12730366 DOI: 10.1073/pnas.1031671100  0.656
2003 Senn BM, López-Macías C, Kalinke U, Lamarre A, Isibasi A, Zinkernagel RM, Hengartner H. Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections. European Journal of Immunology. 33: 950-61. PMID 12672061 DOI: 10.1002/eji.200323340  0.685
2003 Hunziker L, Recher M, Macpherson AJ, Ciurea A, Freigang S, Hengartner H, Zinkernagel RM. Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections. Nature Immunology. 4: 343-9. PMID 12627229 DOI: 10.1038/ni911  0.727
2003 Martinic MM, Rülicke T, Althage A, Odermatt B, Höchli M, Lamarre A, Dumrese T, Speiser DE, Kyburz D, Hengartner H, Zinkernagel RM. Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC. Proceedings of the National Academy of Sciences of the United States of America. 100: 1861-6. PMID 12574503 DOI: 10.1073/pnas.252641399  0.712
2003 Zinkernagel RM. On natural and artificial vaccinations. Annual Review of Immunology. 21: 515-46. PMID 12500980 DOI: 10.1146/annurev.immunol.21.120601.141045  0.447
2003 Hunziker L, Recher M, Macpherson AJ, Hengartner H, Zinkernagel RM. Reply to 'On the implications of polyclonal B cell activation' Nature Immunology. 4: 932-932. DOI: 10.1038/NI1003-932  0.586
2003 Zinkernagel RM. Immunological Memory and Vaccines against Acute Cytopathic and Noncytopathic Infections The Vaccine Book. 149-163. DOI: 10.1016/B978-012107258-2/50013-5  0.289
2002 Hunziker L, Recher M, Ciurea A, Martinic MM, Odermatt B, Hengartner H, Zinkernagel RM. Antagonistic variant virus prevents wild-type virus-induced lethal immunopathology. The Journal of Experimental Medicine. 196: 1039-46. PMID 12391015 DOI: 10.1084/jem.20012045  0.713
2002 Zinkernagel RM. On cross-priming of MHC class I-specific CTL: rule or exception? European Journal of Immunology. 32: 2385-92. PMID 12207322 DOI: 10.1002/1521-4141(200209)32:9<2385::AID-IMMU2385>3.0.CO;2-V  0.498
2002 Zinkernagel RM. Uncertainties - discrepancies in immunology. Immunological Reviews. 185: 103-25. PMID 12190926 DOI: 10.1034/j.1600-065X.2002.18511.x  0.521
2002 Oehen S, Odermatt B, Karrer U, Hengartner H, Zinkernagel R, López-Macías C. Marginal zone macrophages and immune responses against viruses. Journal of Immunology (Baltimore, Md. : 1950). 169: 1453-8. PMID 12133971 DOI: 10.4049/Jimmunol.169.3.1453  0.65
2002 Zinkernagel RM. On differences between immunity and immunological memory. Current Opinion in Immunology. 14: 523-36. PMID 12088689 DOI: 10.1016/S0952-7915(02)00367-9  0.475
2002 Pan Q, Matamoros N, Björkander J, Conley ME, Hammarström L, Macpherson AJ, Lamarre A, Hengartner H, Zinkernagel RM. Lack of IgA in Cμ-deficient patients (multiple letters) Nature Immunology. 3: 595-596. PMID 12087410 DOI: 10.1038/ni0702-595  0.46
2002 Ludewig B, Zinkernagel RM, Hengartner H. Arterial inflammation and atherosclerosis. Trends in Cardiovascular Medicine. 12: 154-9. PMID 12069754 DOI: 10.1016/S1050-1738(01)00166-9  0.566
2002 Pericin M, Althage A, Freigang S, Hengartner H, Rolland E, Dupraz P, Thorens B, Aebischer P, Zinkernagel RM. Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proceedings of the National Academy of Sciences of the United States of America. 99: 8203-6. PMID 12060765 DOI: 10.1073/pnas.122241299  0.59
2002 Junt T, Nakano H, Dumrese T, Kakiuchi T, Odermatt B, Zinkernagel RM, Hengartner H, Ludewig B. Antiviral immune responses in the absence of organized lymphoid T cell zones in plt/plt mice. Journal of Immunology (Baltimore, Md. : 1950). 168: 6032-40. PMID 12055211 DOI: 10.4049/Jimmunol.168.12.6032  0.722
2002 Vento S, Cainelli F, Lemke H, Lange H, Zinkernagel RM. Childhood infections and autoimmune diseases [4] (multiple letters) New England Journal of Medicine. 346: 1749-1750. PMID 12041529 DOI: 10.1056/NEJM200205303462216  0.306
2002 Zinkernagel RM. Antiinfection immunity and autoimmunity. Annals of the New York Academy of Sciences. 958: 3-6. PMID 12021079 DOI: 10.1111/J.1749-6632.2002.Tb02942.X  0.552
2002 Zinkernagel RM. Lymphocytic choriomeningitis virus and immunology. Current Topics in Microbiology and Immunology. 263: 1-5. PMID 11987811 DOI: 10.1007/978-3-642-56055-2_1  0.523
2002 Zinkernagel RM. Immunity, immunopathology and vaccines against HIV? Vaccine. 20: 1913-7. PMID 11983244 DOI: 10.1016/S0264-410X(02)00066-X  0.517
2002 Zinkernagel R. Novartis prizes for immunology 2001, Stockholm Scandinavian Journal of Immunology. 55: 220. PMID 11940226 DOI: 10.1046/j.1365-3083.2002.01060.x  0.439
2002 Bonilla WV, Pinschewer DD, Klenerman P, Rousson V, Gaboli M, Pandolfi PP, Zinkernagel RM, Salvato MS, Hengartner H. Effects of promyelocytic leukemia protein on virus-host balance. Journal of Virology. 76: 3810-8. PMID 11907221 DOI: 10.1128/Jvi.76.8.3810-3818.2002  0.703
2002 Müller S, Hunziker L, Enzler S, Bühler-Jungo M, Di Santo JP, Zinkernagel RM, Mueller C. Role of an intact splenic microarchitecture in early lymphocytic choriomeningitis virus production. Journal of Virology. 76: 2375-83. PMID 11836415 DOI: 10.1128/Jvi.76.5.2375-2383.2002  0.562
2002 Hunziker L, Klenerman P, Zinkernagel RM, Ehl S. Exhaustion of cytotoxic T cells during adoptive immunotherapy of virus carrier mice can be prevented by B cells or CD4+ T cells. European Journal of Immunology. 32: 374-82. PMID 11813156 DOI: 10.1002/1521-4141(200202)32:2<374::AID-IMMU374>3.0.CO;2-9  0.605
2002 Macpherson AJ, Lamarre A, Hengartner H, Zinkernagel RM. Response to 'Lack of IgA in Cμ-deficient patients' Nature Immunology. 3: 596-596. DOI: 10.1038/ni0702-596  0.539
2001 Starzl TE, Zinkernagel RM. Transplantation tolerance from a historical perspective. Nature Reviews. Immunology. 1: 233-9. PMID 11905833 DOI: 10.1038/35105088  0.328
2001 Zinkernagel RM. Maternal antibodies, childhood infections, and autoimmune diseases. The New England Journal of Medicine. 345: 1331-5. PMID 11794153 DOI: 10.1056/NEJMra012493  0.447
2001 Zinkernagel RM, LaMarre A, Ciurea A, Hunziker L, Ochsenbein AF, McCoy KD, Fehr T, Bachmann MF, Kalinke U, Hengartner H. Neutralizing antiviral antibody responses. Advances in Immunology. 79: 1-53. PMID 11680006 DOI: 10.1016/S0065-2776(01)79001-3  0.665
2001 Ludewig B, Junt T, Hengartner H, Zinkernagel RM. Dendritic cells in autoimmune diseases. Current Opinion in Immunology. 13: 657-62. PMID 11677086 DOI: 10.1016/S0952-7915(01)00275-8  0.626
2001 Heppner FL, Musahl C, Arrighi I, Klein MA, Rülicke T, Oesch B, Zinkernagel RM, Kalinke U, Aguzzi A. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science (New York, N.Y.). 294: 178-82. PMID 11546838 DOI: 10.1126/Science.1063093  0.431
2001 Pinschewer DD, Ochsenbein AF, Fehr T, Zinkernagel RM. Leflunomide-mediated suppression of antiviral antibody and Tcell responses: differential restoration by uridine. Transplantation. 72: 712-9. PMID 11544436 DOI: 10.1097/00007890-200108270-00026  0.623
2001 Zinkernagel RM, Hengartner H. Regulation of the immune response by antigen. Science (New York, N.Y.). 293: 251-3. PMID 11452115 DOI: 10.1126/science.1063005  0.656
2001 Ciurea A, Hunziker L, Martinic MM, Oxenius A, Hengartner H, Zinkernagel RM. CD4+ T-cell-epitope escape mutant virus selected in vivo. Nature Medicine. 7: 795-800. PMID 11433343 DOI: 10.1038/89915  0.718
2001 Ochsenbein AF, Sierro S, Odermatt B, Pericin M, Karrer U, Hermans J, Hemmi S, Hengartner H, Zinkernagel RM. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature. 411: 1058-64. PMID 11429607 DOI: 10.1038/35082583  0.681
2001 Macpherson AJ, Lamarre A, McCoy K, Harriman GR, Odermatt B, Dougan G, Hengartner H, Zinkernagel RM. IgA production without mu or delta chain expression in developing B cells. Nature Immunology. 2: 625-31. PMID 11429547 DOI: 10.1038/89775  0.641
2001 Ciurea A, Hunziker L, Zinkernagel RM, Hengartner H. Viral escape from the neutralizing antibody response: the lymphocytic choriomeningitis virus model. Immunogenetics. 53: 185-9. PMID 11398962 DOI: 10.1007/s002510100314  0.683
2001 Zinkernagel RM. Immunity against solid tumors? International Journal of Cancer. Journal International Du Cancer. 93: 1-5. PMID 11391613 DOI: 10.1002/ijc.1305  0.38
2001 Ludewig B, Bonilla WV, Dumrese T, Odermatt B, Zinkernagel RM, Hengartner H. Perforin-independent regulation of dendritic cell homeostasis by CD8(+) T cells in vivo: implications for adaptive immunotherapy. European Journal of Immunology. 31: 1772-9. PMID 11385622 DOI: 10.1002/1521-4141(200106)31:6<1772::AID-IMMU1772>3.0.CO;2-8  0.659
2001 Battegay M, Seiler P, Hunziker L, Wolf K, Zinkernagel RM. Neutralizing antiviral antibodies reduce hematogenic viral spread but not antiviral cytotoxic T cell induction and subsequent immunopathology. The Journal of Infectious Diseases. 183: 1425-7. PMID 11294679 DOI: 10.1086/319871  0.606
2001 Klein MA, Kaeser PS, Schwarz P, Weyd H, Xenarios I, Zinkernagel RM, Carroll MC, Verbeek JS, Botto M, Walport MJ, Molina H, Kalinke U, Acha-Orbea H, Aguzzi A. Complement facilitates early prion pathogenesis. Nature Medicine. 7: 488-92. PMID 11283678 DOI: 10.1038/86567  0.512
2001 Maloy KJ, Erdmann I, Basch V, Sierro S, Kramps TA, Zinkernagel RM, Oehen S, Kündig TM. Intralymphatic immunization enhances DNA vaccination. Proceedings of the National Academy of Sciences of the United States of America. 98: 3299-303. PMID 11248073 DOI: 10.1073/pnas.051630798  0.408
2001 Ludewig B, McCoy K, Pericin M, Ochsenbein AF, Dumrese T, Odermatt B, Toes RE, Melief CJ, Hengartner H, Zinkernagel RM. Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 3678-87. PMID 11238607 DOI: 10.4049/Jimmunol.166.6.3678  0.588
2001 Ludewig B, Jäggi M, Dumrese T, Brduscha-Riem K, Odermatt B, Hengartner H, Zinkernagel RM. Hypercholesterolemia exacerbates virus-induced immunopathologic liver disease via suppression of antiviral cytotoxic T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 166: 3369-76. PMID 11207293 DOI: 10.4049/Jimmunol.166.5.3369  0.686
2001 Ciurea A, Hunziker L, Klenerman P, Hengartner H, Zinkernagel RM. Impairment of CD4(+) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants. The Journal of Experimental Medicine. 193: 297-305. PMID 11157050 DOI: 10.1084/jem.193.3.297  0.708
2001 Ochsenbein AF, Sierro S, Odermatt B, Pericin M, Karrer U, Hermans I, Hemmi S, Hengartner H, Zinkernagel RM. Erratum: Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction Nature. 413: 183-183. DOI: 10.1038/35093138  0.39
2000 Moretta L, Moretta A, Hengartner H, Zinkernagel RM. On the pathogenesis of perforin defects and related immunodeficiencies. Immunology Today. 21: 593-4. PMID 11221685 DOI: 10.1016/S0167-5699(00)01731-X  0.666
2000 Ludewig B, Zinkernagel RM, Hengartner H. Transgenic animal models for virus-induced autoimmune diseases. Experimental Physiology. 85: 653-9. PMID 11187961 DOI: 10.1111/J.1469-445X.2000.02093.X  0.661
2000 Zinkernagel RM. Assessing the mechanisms that give rise to autoimmunity. Science (New York, N.Y.). 290: 11. PMID 11183137 DOI: 10.1126/Science.290.5489.11A  0.456
2000 Ochsenbein AF, Zinkernagel RM. Natural antibodies and complement link innate and acquired immunity. Immunology Today. 21: 624-30. PMID 11114423 DOI: 10.1016/S0167-5699(00)01754-0  0.498
2000 Ochsenbein AF, Pinschewer DD, Sierro S, Horvath E, Hengartner H, Zinkernagel RM. Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs. Proceedings of the National Academy of Sciences of the United States of America. 97: 13263-8. PMID 11069289 DOI: 10.1073/pnas.230417497  0.659
2000 Karrer U, Althage A, Odermatt B, Hengartner H, Zinkernagel RM. Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: structural defect of secondary lymphoid organs and functional B cell defect. European Journal of Immunology. 30: 2799-807. PMID 11069060 DOI: 10.1002/1521-4141(200010)30:10<2799::AID-IMMU2799>3.0.CO;2-2  0.68
2000 Ludewig B, Freigang S, Jäggi M, Kurrer MO, Pei YC, Vlk L, Odermatt B, Zinkernagel RM, Hengartner H. Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America. 97: 12752-7. PMID 11050173 DOI: 10.1073/pnas.220427097  0.595
2000 Klenerman P, Lechner F, Kantzanou M, Ciurea A, Hengartner H, Zinkernagel R. Viral escape and the failure of cellular immune responses. Science (New York, N.Y.). 289: 2003. PMID 11032545 DOI: 10.1126/SCIENCE.289.5487.2003A  0.598
2000 Zinkernagel RM. What is missing in immunology to understand immunity? Nature Immunology. 1: 181-5. PMID 10973269 DOI: 10.1038/79712  0.447
2000 Fehr T, López-Macías C, Odermatt B, Torres RM, Schubart DB, O'Keefe TL, Matthias P, Hengartner H, Zinkernagel RM. Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules. International Immunology. 12: 1275-84. PMID 10967022 DOI: 10.1093/INTIMM/12.9.1275  0.718
2000 Kalinke U, Oxenius A, Lopez-Macias C, Zinkernagel RM, Hengartner H. Virus neutralization by germ-line vs. hypermutated antibodies. Proceedings of the National Academy of Sciences of the United States of America. 97: 10126-31. PMID 10963674 DOI: 10.1073/Pnas.97.18.10126  0.622
2000 Zinkernagel RM. Immunity 2000. Immunology Today. 21: 422-3. PMID 10953092 DOI: 10.1016/S0167-5699(00)01671-6  0.324
2000 Ludewig B, Barchiesi F, Pericin M, Zinkernagel RM, Hengartner H, Schwendener RA. In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity. Vaccine. 19: 23-32. PMID 10924783 DOI: 10.1016/S0264-410X(00)00163-8  0.628
2000 Zinkernagel RM. Localization dose and time of antigens determine immune reactivity. Seminars in Immunology. 12: 163-71; discussion 2. PMID 10910735 DOI: 10.1006/smim.2000.0253  0.559
2000 Knobeloch KP, Wright MD, Ochsenbein AF, Liesenfeld O, Löhler J, Zinkernagel RM, Horak I, Orinska Z. Targeted inactivation of the tetraspanin CD37 impairs T-cell-dependent B-cell response under suboptimal costimulatory conditions. Molecular and Cellular Biology. 20: 5363-9. PMID 10891477 DOI: 10.1128/MCB.20.15.5363-5369.2000  0.527
2000 Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science (New York, N.Y.). 288: 2222-6. PMID 10864873 DOI: 10.1126/science.288.5474.2222  0.653
2000 Maloy KJ, Burkhart C, Junt TM, Odermatt B, Oxenius A, Piali L, Zinkernagel RM, Hengartner H. CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability. The Journal of Experimental Medicine. 191: 2159-70. PMID 10859340 DOI: 10.1084/jem.191.12.2159  0.698
2000 Seiler P, Senn BM, Klenerman P, Kalinke U, Hengartner H, Zinkernagel RM. Additive effect of neutralizing antibody and antiviral drug treatment in preventing virus escape and persistence. Journal of Virology. 74: 5896-901. PMID 10846070 DOI: 10.1128/JVI.74.13.5896-5901.2000  0.659
2000 Ochsenbein AF, Pinschewer DD, Odermatt B, Ciurea A, Hengartner H, Zinkernagel RM. Correlation of T cell independence of antibody responses with antigen dose reaching secondary lymphoid organs: implications for splenectomized patients and vaccine design. Journal of Immunology (Baltimore, Md. : 1950). 164: 6296-302. PMID 10843683 DOI: 10.4049/Jimmunol.164.12.6296  0.673
2000 Barchet W, Oehen S, Klenerman P, Wodarz D, Bocharov G, Lloyd AL, Nowak MA, Hengartner H, Zinkernagel RM, Ehl S. Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo. European Journal of Immunology. 30: 1356-63. PMID 10820382 DOI: 10.1002/(Sici)1521-4141(200005)30:5<1356::Aid-Immu1356>3.0.Co;2-K  0.72
2000 Pinschewer DD, Ochsenbein AF, Odermatt B, Brinkmann V, Hengartner H, Zinkernagel RM. FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory. Journal of Immunology (Baltimore, Md. : 1950). 164: 5761-70. PMID 10820254 DOI: 10.4049/Jimmunol.164.11.5761  0.727
2000 Zinkernagel RM. On immunological memory. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 369-71. PMID 10794057 DOI: 10.1098/rstb.2000.0576  0.489
2000 Ehl S, Barchet W, Oehen S, Aichele P, Hombach J, Hengartner H, Zinkernagel RM. Donor cell persistence and activation-induced unresponsiveness of peripheral CD8+ T cells. European Journal of Immunology. 30: 883-91. PMID 10741405 DOI: 10.1002/1521-4141(200003)30:3<883::AID-IMMU883>3.0.CO;2-U  0.718
2000 Ludewig B, Ochsenbein AF, Odermatt B, Paulin D, Hengartner H, Zinkernagel RM. Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune disease. The Journal of Experimental Medicine. 191: 795-804. PMID 10704461 DOI: 10.1084/jem.191.5.795  0.619
2000 Ciurea A, Klenerman P, Hunziker L, Horvath E, Senn BM, Ochsenbein AF, Hengartner H, Zinkernagel RM. Viral persistence in vivo through selection of neutralizing antibody-escape variants. Proceedings of the National Academy of Sciences of the United States of America. 97: 2749-54. PMID 10688894 DOI: 10.1073/pnas.040558797  0.686
2000 Karrer U, López-Macías C, Oxenius A, Odermatt B, Bachmann MF, Kalinke U, Bluethmann H, Hengartner H, Zinkernagel RM. Antiviral B cell memory in the absence of mature follicular dendritic cell networks and classical germinal centers in TNFR1-/- mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 768-78. PMID 10623822 DOI: 10.4049/Jimmunol.164.2.768  0.657
2000 van Den Broek M, Bachmann MF, Köhler G, Barner M, Escher R, Zinkernagel R, Kopf M. IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2. Journal of Immunology (Baltimore, Md. : 1950). 164: 371-8. PMID 10605032 DOI: 10.4049/jimmunol.164.1.371  0.343
2000 Ludewig B, Maloy KJ, López-Macías C, Odermatt B, Hengartner H, Zinkernagel RM. Induction of optimal anti-viral neutralizing B cell responses by dendritic cells requires transport and release of virus particles in secondary lymphoid organs. European Journal of Immunology. 30: 185-96. PMID 10602040 DOI: 10.1002/1521-4141(200001)30:1<185::AID-IMMU185>3.0.CO;2-L  0.699
1999 Klenerman P, Zinkernagel RM. Of mice and men: cytotoxic T cells and AIDS pathogenesis. The Aids Reader. 9: 474-80. PMID 12737139  0.475
1999 Ochsenbein AF, Fehr T, Lutz C, Suter M, Brombacher F, Hengartner H, Zinkernagel RM. Control of early viral and bacterial distribution and disease by natural antibodies. Science (New York, N.Y.). 286: 2156-9. PMID 10591647 DOI: 10.1126/science.286.5447.2156  0.644
1999 Ochsenbein AF, Pinschewer DD, Odermatt B, Carroll MC, Hengartner H, Zinkernagel RM. Protective T cell-independent antiviral antibody responses are dependent on complement. The Journal of Experimental Medicine. 190: 1165-74. PMID 10523614 DOI: 10.1084/jem.190.8.1165  0.718
1999 Ciurea A, Klenerman P, Hunziker L, Horvath E, Odermatt B, Ochsenbein AF, Hengartner H, Zinkernagel RM. Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 11964-9. PMID 10518559 DOI: 10.1073/pnas.96.21.11964  0.689
1999 Frigg R, Klein MA, Hegyi I, Zinkernagel RM, Aguzzi A. Scrapie pathogenesis in subclinically infected B-cell-deficient mice. Journal of Virology. 73: 9584-8. PMID 10516067 DOI: 10.1128/Jvi.73.11.9584-9588.1999  0.496
1999 Pinschewer DD, Ochsenbein AF, Satterthwaite AB, Witte ON, Hengartner H, Zinkernagel RM. A Btk transgene restores the antiviral TI-2 antibody responses of xid mice in a dose-dependent fashion. European Journal of Immunology. 29: 2981-7. PMID 10508272 DOI: 10.1002/(SICI)1521-4141(199909)29:09<2981::AID-IMMU2981>3.0.CO;2-Y  0.672
1999 Ludewig B, Odermatt B, Ochsenbein AF, Zinkernagel RM, Hengartner H. Role of dendritic cells in the induction and maintenance of autoimmune diseases. Immunological Reviews. 169: 45-54. PMID 10450507 DOI: 10.1111/j.1600-065X.1999.tb01305.x  0.602
1999 Ludewig B, Oehen S, Barchiesi F, Schwendener RA, Hengartner H, Zinkernagel RM. Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 163: 1839-44. PMID 10438917 DOI: 10.5167/Uzh-19974  0.685
1999 Ochsenbein AF, Karrer U, Klenerman P, Althage A, Ciurea A, Shen H, Miller JF, Whitton JL, Hengartner H, Zinkernagel RM. A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria. Proceedings of the National Academy of Sciences of the United States of America. 96: 9293-8. PMID 10430936 DOI: 10.1073/Pnas.96.16.9293  0.694
1999 Zinkernagel RM, Planz O, Ehl S, Battegay M, Odermatt B, Klenerman P, Hengartner H. General and specific immunosuppression caused by antiviral T-cell responses. Immunological Reviews. 168: 305-15. PMID 10399082 DOI: 10.1111/j.1600-065X.1999.tb01300.x  0.747
1999 Zinkernagel RM, Althage A. On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 8092-7. PMID 10393953 DOI: 10.1073/pnas.96.14.8092  0.574
1999 López-Macías C, Kalinke U, Cascalho M, Wabl M, Hengartner H, Zinkernagel RM, Lamarre A. Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses. The Journal of Experimental Medicine. 189: 1791-8. PMID 10359583 DOI: 10.1084/jem.189.11.1791  0.69
1999 Seiler P, Senn BM, Bründler MA, Zinkernagel RM, Hengartner H, Kalinke U. In vivo selection of neutralization-resistant virus variants but no evidence of B cell tolerance in lymphocytic choriomeningitis virus carrier mice expressing a transgenic virus-neutralizing antibody. Journal of Immunology (Baltimore, Md. : 1950). 162: 4536-41. PMID 10201992  0.646
1999 Maloy KJ, Burkhart C, Freer G, Rülicke T, Pircher H, Kono DH, Theofilopoulos AN, Ludewig B, Hoffmann-Rohrer U, Zinkernagel RM, Hengartner H. Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection. Journal of Immunology (Baltimore, Md. : 1950). 162: 2867-74. PMID 10072535  0.669
1999 Ochsenbein AF, Klenerman P, Karrer U, Ludewig B, Pericin M, Hengartner H, Zinkernagel RM. Immune surveillance against a solid tumor fails because of immunological ignorance. Proceedings of the National Academy of Sciences of the United States of America. 96: 2233-8. PMID 10051624 DOI: 10.1073/pnas.96.5.2233  0.631
1999 Steinhoff U, Maloy KJ, Burkhart C, Clark AJ, Rülicke T, Hengartner H, Zinkernagel RM. Variable immune response against a developmentally regulated self-antigen. Journal of Autoimmunity. 12: 27-34. PMID 10028019 DOI: 10.1006/jaut.1998.0254  0.668
1999 Oxenius A, Karrer U, Zinkernagel RM, Hengartner H. IL-12 is not required for induction of type 1 cytokine responses in viral infections. Journal of Immunology (Baltimore, Md. : 1950). 162: 965-73. PMID 9916721  0.635
1998 Starzl TE, Zinkernagel RM. Antigen localization and migration in immunity and tolerance. The New England Journal of Medicine. 339: 1905-13. PMID 9862947 DOI: 10.1056/Nejm199812243392607  0.481
1998 Klein MA, Frigg R, Raeber AJ, Flechsig E, Hegyi I, Zinkernagel RM, Weissmann C, Aguzzi A. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nature Medicine. 4: 1429-33. PMID 9846583 DOI: 10.1038/4022  0.526
1998 Bachmann MF, Zinkernagel RM, Oxenius A. Immune responses in the absence of costimulation: viruses know the trick. Journal of Immunology (Baltimore, Md. : 1950). 161: 5791-4. PMID 9834052  0.367
1998 Gallimore A, Hombach J, Dumrese T, Rammensee HG, Zinkernagel RM, Hengartner H. A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells. European Journal of Immunology. 28: 3301-11. PMID 9808199 DOI: 10.1002/(SICI)1521-4141(199810)28:10<3301::AID-IMMU3301>3.0.CO;2-Q  0.638
1998 Oxenius A, Zinkernagel RM, Hengartner H. Comparison of activation versus induction of unresponsiveness of virus-specific CD4+ and CD8+ T cells upon acute versus persistent viral infection. Immunity. 9: 449-57. PMID 9806631 DOI: 10.1016/S1074-7613(00)80628-7  0.682
1998 Gallimore A, Hengartner H, Zinkernagel R. Hierarchies of antigen-specific cytotoxic T-cell responses. Immunological Reviews. 164: 29-36. PMID 9795761 DOI: 10.1111/j.1600-065X.1998.tb01205.x  0.703
1998 André P, Groettrup M, Klenerman P, de Giuli R, Booth BL, Cerundolo V, Bonneville M, Jotereau F, Zinkernagel RM, Lotteau V. An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses. Proceedings of the National Academy of Sciences of the United States of America. 95: 13120-4. PMID 9789051 DOI: 10.1073/Pnas.95.22.13120  0.501
1998 Ludewig B, Odermatt B, Landmann S, Hengartner H, Zinkernagel RM. Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue. The Journal of Experimental Medicine. 188: 1493-501. PMID 9782126 DOI: 10.1084/jem.188.8.1493  0.678
1998 Ehl S, Klenerman P, Zinkernagel RM, Bocharov G. The impact of variation in the number of CD8(+) T-cell precursors on the outcome of virus infection. Cellular Immunology. 189: 67-73. PMID 9758696 DOI: 10.1006/cimm.1998.1344  0.546
1998 Oxenius A, Zinkernagel RM, Hengartner H. CD4+ T-cell induction and effector functions: a comparison of immunity against soluble antigens and viral infections. Advances in Immunology. 70: 313-67. PMID 9755341 DOI: 10.1016/S0065-2776(08)60390-9  0.718
1998 Ehl S, Aichele P, Ramseier H, Barchet W, Hombach J, Pircher H, Hengartner H, Zinkernagel RM. Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection. Nature Medicine. 4: 1015-9. PMID 9734393 DOI: 10.1038/2001  0.63
1998 Fehr T, Naim HY, Bachmann MF, Ochsenbein AF, Spielhofer P, Bucher E, Hengartner H, Billeter MA, Zinkernagel RM. T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses. Nature Medicine. 4: 945-8. PMID 9701248 DOI: 10.1038/nm0898-945  0.725
1998 Klenerman P, Zinkernagel RM. Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature. 394: 482-5. PMID 9697771 DOI: 10.1038/28860  0.627
1998 Fehr T, Skrastina D, Pumpens P, Zinkernagel RM. T cell-independent type I antibody response against B cell epitopes expressed repetitively on recombinant virus particles. Proceedings of the National Academy of Sciences of the United States of America. 95: 9477-81. PMID 9689105 DOI: 10.1073/pnas.95.16.9477  0.549
1998 Lutz C, Ledermann B, Kosco-Vilbois MH, Ochsenbein AF, Zinkernagel RM, Köhler G, Brombacher F. IgD can largely substitute for loss of IgM function in B cells. Nature. 393: 797-801. PMID 9655395 DOI: 10.1038/31716  0.544
1998 Fehr T, Rickert RC, Odermatt B, Roes J, Rajewsky K, Hengartner H, Zinkernagel RM. Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19. The Journal of Experimental Medicine. 188: 145-55. PMID 9653091 DOI: 10.1084/Jem.188.1.145  0.664
1998 Binder D, van den Broek MF, Kägi D, Bluethmann H, Fehr J, Hengartner H, Zinkernagel RM. Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus. The Journal of Experimental Medicine. 187: 1903-20. PMID 9607930 DOI: 10.1084/jem.187.11.1903  0.729
1998 Gallimore A, Dumrese T, Hengartner H, Zinkernagel RM, Rammensee HG. Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides. The Journal of Experimental Medicine. 187: 1647-57. PMID 9584143 DOI: 10.1084/jem.187.10.1647  0.688
1998 Gallimore A, Glithero A, Godkin A, Tissot AC, Plückthun A, Elliott T, Hengartner H, Zinkernagel R. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. The Journal of Experimental Medicine. 187: 1383-93. PMID 9565631 DOI: 10.1084/Jem.187.9.1383  0.72
1998 Ludewig B, Ehl S, Karrer U, Odermatt B, Hengartner H, Zinkernagel RM. Dendritic cells efficiently induce protective antiviral immunity. Journal of Virology. 72: 3812-8. PMID 9557664 DOI: 10.1128/Jvi.72.5.3812-3818.1998  0.673
1998 Seiler P, Kalinke U, Rülicke T, Bucher EM, Böse C, Zinkernagel RM, Hengartner H. Enhanced virus clearance by early inducible lymphocytic choriomeningitis virus-neutralizing antibodies in immunoglobulin-transgenic mice. Journal of Virology. 72: 2253-8. PMID 9499083 DOI: 10.1128/Jvi.72.3.2253-2258.1998  0.662
1998 Oxenius A, Bachmann MF, Zinkernagel RM, Hengartner H. Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection. European Journal of Immunology. 28: 390-400. PMID 9485218 DOI: 10.1002/(SICI)1521-4141(199801)28:01<390::AID-IMMU390>3.0.CO;2-O  0.744
1998 Ehl S, Hombach J, Aichele P, Rülicke T, Odermatt B, Hengartner H, Zinkernagel R, Pircher H. Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology. The Journal of Experimental Medicine. 187: 763-74. PMID 9480986 DOI: 10.1084/jem.187.5.763  0.72
1998 Seiler P, Bründler MA, Zimmermann C, Weibel D, Bruns M, Hengartner H, Zinkernagel RM. Induction of protective cytotoxic T cell responses in the presence of high titers of virus-neutralizing antibodies: implications for passive and active immunization. The Journal of Experimental Medicine. 187: 649-54. PMID 9463415 DOI: 10.1084/jem.187.4.649  0.713
1998 Maloy KJ, Odermatt B, Hengartner H, Zinkernagel RM. Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection. Proceedings of the National Academy of Sciences of the United States of America. 95: 1160-5. PMID 9448302 DOI: 10.1073/pnas.95.3.1160  0.755
1998 Moskohidis D, Laine E, Zinkernagel RM. Correction: Peripheral clonal deletion of antiviral memory CD8+ T cells (European Journal of Immunology (1993) 23 (3306-3311)) European Journal of Immunology. 28: 2978-2979.  0.401
1998 Zinkernagel RM. Anti-viral immunity Central-European Journal of Immunology. 23: 3-7.  0.396
1997 Ehl S, Klenerman P, Aichele P, Hengartner H, Zinkernagel RM. A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro. European Journal of Immunology. 27: 3404-13. PMID 9464829 DOI: 10.1002/eji.1830271240  0.698
1997 Klenerman P, Zinkernagel RM. What can we learn about human immunodeficiency virus infection from a study of lymphocytic choriomeningitis virus? Immunological Reviews. 159: 5-16. PMID 9416499 DOI: 10.1111/J.1600-065X.1997.Tb01003.X  0.557
1997 Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, Bluethmann H, Bootz F, Suter M, Zinkernagel RM, Aguzzi A. A crucial role for B cells in neuroinvasive scrapie. Nature. 390: 687-90. PMID 9414161 DOI: 10.1038/37789  0.547
1997 Zinkernagel RM. Gene technology and democracy. Science (New York, N.Y.). 278: 1207. PMID 9411739 DOI: 10.1126/science.278.5341.1207  0.325
1997 Zinkernagel RM. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1996. Cellular immune recognition and the biological role of major transplantation antigens. Scandinavian Journal of Immunology. 46: 421-36. PMID 9393624  0.352
1997 Klenerman P, Hengartner H, Zinkernagel RM. A non-retroviral RNA virus persists in DNA form. Nature. 390: 298-301. PMID 9384383 DOI: 10.1038/36876  0.628
1997 Zinkernagel RM. Felix Hoppe-Seyler Lecture 1997. Protective antibody responses against viruses. Biological Chemistry. 378: 725-9. PMID 9377466  0.513
1997 Seiler P, Aichele P, Odermatt B, Hengartner H, Zinkernagel RM, Schwendener RA. Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection. European Journal of Immunology. 27: 2626-33. PMID 9368619 DOI: 10.1002/eji.1830271023  0.715
1997 Bachmann MF, Oxenius A, Speiser DE, Mariathasan S, Hengartner H, Zinkernagel RM, Ohashi PS. Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation. European Journal of Immunology. 27: 2195-203. PMID 9341759 DOI: 10.1002/Eji.1830270912  0.653
1997 Kägi D, Odermatt B, Seiler P, Zinkernagel RM, Mak TW, Hengartner H. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. The Journal of Experimental Medicine. 186: 989-97. PMID 9314549 DOI: 10.1084/jem.186.7.989  0.608
1997 Speiser DE, Miranda R, Zakarian A, Bachmann MF, McKall-Faienza K, Odermatt B, Hanahan D, Zinkernagel RM, Ohashi PS. Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy. The Journal of Experimental Medicine. 186: 645-53. PMID 9271580 DOI: 10.1084/Jem.186.5.645  0.533
1997 van den Broek MF, Spörri R, Even C, Plagemann PG, Hänseler E, Hengartner H, Zinkernagel RM. Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 159: 1585-8. PMID 9257815 DOI: 10.1016/S0165-2478(97)86210-4  0.683
1997 Zinkernagel RM. Cellular immune recognition and the biological role of major transplantation antigens. Bioscience Reports. 17: 91-111. PMID 9217962 DOI: 10.1023/A:1027303227595  0.598
1997 Zinkernagel R, Klenerman P. Immune surveillance and AIDS progression. Current Biology : Cb. 7: R403-5. PMID 9210384 DOI: 10.1016/S0960-9822(06)00201-6  0.647
1997 Bachmann MF, Kalinke U, Althage A, Freer G, Burkhart C, Roost H, Aguet M, Hengartner H, Zinkernagel RM. The role of antibody concentration and avidity in antiviral protection. Science (New York, N.Y.). 276: 2024-7. PMID 9197261 DOI: 10.1126/Science.276.5321.2024  0.564
1997 Planz O, Ehl S, Furrer E, Horvath E, Bründler MA, Hengartner H, Zinkernagel RM. A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proceedings of the National Academy of Sciences of the United States of America. 94: 6874-9. PMID 9192659 DOI: 10.1073/pnas.94.13.6874  0.731
1997 Oxenius A, Bachmann MF, Mathis D, Benoist C, Zinkernagel RM, Hengartner H. Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 158: 5717-26. PMID 9190921  0.585
1997 Zinkernagel RM, Hengartner H. Antiviral immunity. Immunology Today. 18: 258-60. PMID 9190107 DOI: 10.1016/S0167-5699(97)80017-5  0.667
1997 Karrer U, Althage A, Odermatt B, Roberts CW, Korsmeyer SJ, Miyawaki S, Hengartner H, Zinkernagel RM. On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice. The Journal of Experimental Medicine. 185: 2157-70. PMID 9182687 DOI: 10.1084/jem.185.12.2157  0.715
1997 Zinkernagel RM, Ehl S, Aichele P, Oehen S, Kündig T, Hengartner H. Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity. Immunological Reviews. 156: 199-209. PMID 9176709 DOI: 10.1111/J.1600-065X.1997.Tb00969.X  0.681
1997 Aichele P, Brduscha-Riem K, Oehen S, Odermatt B, Zinkernagel RM, Hengartner H, Pircher H. Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology. Immunity. 6: 519-29. PMID 9175830 DOI: 10.1016/S1074-7613(00)80340-4  0.684
1997 Bachmann MF, Fehr T, Freer G, Hengartner H, Zinkernagel RM. Correlation of tolerogenicity of a viral antigen with its immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 158: 5106-11. PMID 9164925  0.612
1997 Fehr T, Bachmann MF, Bucher E, Kalinke U, Di Padova FE, Lang AB, Hengartner H, Zinkernagel RM. Role of repetitive antigen patterns for induction of antibodies against antibodies. The Journal of Experimental Medicine. 185: 1785-92. PMID 9151704 DOI: 10.1084/jem.185.10.1785  0.636
1997 Bachmann MF, Zinkernagel RM. Neutralizing antiviral B cell responses. Annual Review of Immunology. 15: 235-70. PMID 9143688 DOI: 10.1146/annurev.immunol.15.1.235  0.516
1997 Fehr T, Schoedon G, Odermatt B, Holtschke T, Schneemann M, Bachmann MF, Mak TW, Horak I, Zinkernagel RM. Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. The Journal of Experimental Medicine. 185: 921-31. PMID 9120398 DOI: 10.1084/jem.185.5.921  0.368
1997 Zinkernagel RM. Immunology and immunity studied with viruses. Ciba Foundation Symposium. 204: 105-25; discussion 1. PMID 9107415  0.547
1997 Ehl S, Hombach J, Aichele P, Hengartner H, Zinkernagel RM. Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model. The Journal of Experimental Medicine. 185: 1241-51. PMID 9104811 DOI: 10.1084/jem.185.7.1241  0.717
1997 Binder D, Fehr J, Hengartner H, Zinkernagel RM. Virus-induced transient bone marrow aplasia: major role of interferon-alpha/beta during acute infection with the noncytopathic lymphocytic choriomeningitis virus. The Journal of Experimental Medicine. 185: 517-30. PMID 9053452 DOI: 10.1084/jem.185.3.517  0.634
1997 Zimmermann C, Seiler P, Lane P, Zinkernagel RM. Antiviral immune responses in CTLA4 transgenic mice. Journal of Virology. 71: 1802-7. PMID 9032309 DOI: 10.1128/Jvi.71.3.1802-1807.1997  0.64
1997 Zinkernagel RM, Doherty PC. The discovery of MHC restriction. Immunology Today. 18: 14-7. PMID 9018968 DOI: 10.1016/S0167-5699(97)80008-4  0.64
1997 Bachmann MF, Kündig TM, Hengartner H, Zinkernagel RM. Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"? Proceedings of the National Academy of Sciences of the United States of America. 94: 640-5. PMID 9012837 DOI: 10.1073/pnas.94.2.640  0.704
1997 Bloom B, Zinkernagel R. Immunity to infection. Current Opinion in Immunology. 8: 465-6. PMID 8794023 DOI: 10.1016/S0952-7915(96)80031-8  0.371
1997 Doherty PC, Zinkernagel RM. The Nobel Lectures in Immunology The Nobel Prize for Physiology or Medicine, 1996 awarded to Scandinavian Journal of Immunology. 46: 421-422. DOI: 10.1046/J.1365-3083.1997.D01-149.X  0.498
1997 Zinkernagel RM, Bachmann MF, Kündig TM, Hengartner H. Response from Zinkernagel et al Trends in Microbiology. 5: 260-261. DOI: 10.1016/S0966-842X(97)01074-3  0.496
1997 Seiler P, Senn B, Bründler M, Zinkernagel R, Hengartner H. No B cell tolerance, but generation of antibody escape mutants in vivo in anti-lymphocytic choriomeningitis virus specific antibody transgenic mice Immunology Letters. 56: 249. DOI: 10.1016/S0165-2478(97)85990-1  0.623
1997 Aichele P, Brduscha-Riem K, Oehen S, Zinkernagel R, Hengartner H, Pircher H. Peptide-antigen treatment of naive and memory CTL: Antigen-specific tolerization versus immunopathology Immunology Letters. 56: 34. DOI: 10.1016/S0165-2478(97)85130-9  0.54
1997 Zinkernagel RM. Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens(Nobel Lecture) Angewandte Chemie International Edition in English. 36: 1938-1949. DOI: 10.1002/ANIE.199719381  0.352
1997 Zinkernagel RM. Le soi, le non-soi et les virus Medecine Et Hygiene. 55: 1749-1760.  0.256
1996 Zinkernagel RM, Hengartner H. Correlates of Protective Viruses Damaging to HIV Infection. Science (New York, N.Y.). 272: 1362a. PMID 17832186 DOI: 10.1126/science.272.5266.1362a  0.554
1996 Zinkernagel RM. Response: immunology taught by darwin. Science (New York, N.Y.). 272: 635a. PMID 17821450 DOI: 10.1126/science.272.5262.635a  0.28
1996 Bachmann MF, Zinkernagel RM. The influence of virus structure on antibody responses and virus serotype formation. Immunology Today. 17: 553-8. PMID 8991286 DOI: 10.1016/S0167-5699(96)10066-9  0.488
1996 Kalinke U, Bucher EM, Ernst B, Oxenius A, Roost HP, Geley S, Kofler R, Zinkernagel RM, Hengartner H. The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus. Immunity. 5: 639-52. PMID 8986722 DOI: 10.1016/S1074-7613(00)80277-0  0.646
1996 Ehl S, Nuesch R, Tanaka T, Myasaka M, Hengartner H, Zinkernagel R. A comparison of efficacy and specificity of three NK depleting antibodies. Journal of Immunological Methods. 199: 149-53. PMID 8982356 DOI: 10.1016/S0022-1759(96)00175-5  0.661
1996 Kalinke U, Krebber A, Krebber C, Bucher E, Plückthun A, Zinkernagel RM, Hengartner H. Monovalent single-chain Fv fragments and bivalent miniantibodies bound to vesicular stomatitis virus protect against lethal infection. European Journal of Immunology. 26: 2801-6. PMID 8977271 DOI: 10.1002/Eji.1830261202  0.676
1996 Aichele P, Bachmann MF, Hengartner H, Zinkernagel RM. Immunopathology or organ-specific autoimmunity as a consequence of virus infection. Immunological Reviews. 152: 21-45. PMID 8930666 DOI: 10.1111/J.1600-065X.1996.Tb00909.X  0.624
1996 van den Broek ME, Kägi D, Ossendorp F, Toes R, Vamvakas S, Lutz WK, Melief CJ, Zinkernagel RM, Hengartner H. Decreased tumor surveillance in perforin-deficient mice. The Journal of Experimental Medicine. 184: 1781-90. PMID 8920866 DOI: 10.1084/Jem.184.5.1781  0.631
1996 Holtschke T, Löhler J, Kanno Y, Fehr T, Giese N, Rosenbauer F, Lou J, Knobeloch KP, Gabriele L, Waring JF, Bachmann MF, Zinkernagel RM, Morse HC, Ozato K, Horak I. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell. 87: 307-17. PMID 8861914 DOI: 10.1016/S0092-8674(00)81348-3  0.479
1996 Bründler MA, Aichele P, Bachmann M, Kitamura D, Rajewsky K, Zinkernagel RM. Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory. European Journal of Immunology. 26: 2257-62. PMID 8814275 DOI: 10.1002/Eji.1830260943  0.617
1996 Kündig TM, Bachmann MF, Oehen S, Hoffmann UW, Simard JJ, Kalberer CP, Pircher H, Ohashi PS, Hengartner H, Zinkernagel RM. On the role of antigen in maintaining cytotoxic T-cell memory. Proceedings of the National Academy of Sciences of the United States of America. 93: 9716-23. PMID 8790397 DOI: 10.1073/pnas.93.18.9716  0.707
1996 Kündig TM, Bachmann MF, Ohashi PS, Pircher H, Hengartner H, Zinkernagel RM. On T cell memory: arguments for antigen dependence. Immunological Reviews. 150: 63-90. PMID 8782702 DOI: 10.1111/J.1600-065X.1996.Tb00696.X  0.671
1996 Planz O, Seiler P, Hengartner H, Zinkernagel RM. Specific cytotoxic T cells eliminate B cells producing virus-neutralizing antibodies [corrected]. Nature. 382: 726-9. PMID 8751445 DOI: 10.1038/382726a0  0.676
1996 Zinkernagel RM, Bachmann MF, Kündig TM, Oehen S, Pirchet H, Hengartner H. On immunological memory. Annual Review of Immunology. 14: 333-67. PMID 8717518 DOI: 10.1146/annurev.immunol.14.1.333  0.708
1996 Kägi D, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annual Review of Immunology. 14: 207-32. PMID 8717513 DOI: 10.1146/annurev.immunol.14.1.207  0.714
1996 Eugster HP, Muller M, Karrer U, Car BD, Schnyder B, Eng VM, Woerly G, Le Hir M, di Padova F, Aguet M, Zinkernagel R, Bluethmann H, Ryffel B. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. International Immunology. 8: 23-36. PMID 8671586 DOI: 10.1093/Intimm/8.1.23  0.581
1996 Zimmerman C, Brduscha-Riem K, Blaser C, Zinkernagel RM, Pircher H. Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts. The Journal of Experimental Medicine. 183: 1367-75. PMID 8666895  0.515
1996 Zinkernagel RM, Hengartner H. Correlates of protective viruses damaging to HIV infection. Science (New York, N.Y.). 272: 1362. PMID 8650554  0.503
1996 Bachmann MF, Odermatt B, Hengartner H, Zinkernagel RM. Induction of long-lived germinal centers associated with persisting antigen after viral infection. The Journal of Experimental Medicine. 183: 2259-69. PMID 8642335 DOI: 10.1084/jem.183.5.2259  0.681
1996 Oxenius A, Campbell KA, Maliszewski CR, Kishimoto T, Kikutani H, Hengartner H, Zinkernagel RM, Bachmann MF. CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions. The Journal of Experimental Medicine. 183: 2209-18. PMID 8642330 DOI: 10.1084/jem.183.5.2209  0.69
1996 Kägi D, Odermatt B, Ohashi PS, Zinkernagel RM, Hengartner H. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity. The Journal of Experimental Medicine. 183: 2143-52. PMID 8642324 DOI: 10.1084/jem.183.5.2143  0.695
1996 Fehr T, Bachmann MF, Bluethmann H, Kikutani H, Hengartner H, Zinkernagel RM. T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal. Cellular Immunology. 168: 184-92. PMID 8640864 DOI: 10.1006/cimm.1996.0065  0.711
1996 Roost HP, Haag A, Burkhart C, Zinkernagel RM, Hengartner H. Mapping of the dominant neutralizing antigenic site of a virus using infected cells. Journal of Immunological Methods. 189: 233-42. PMID 8613674 DOI: 10.1016/0022-1759(95)00252-9  0.66
1996 Battegay M, Fiedler P, Kalinke U, Brombacher F, Zinkernagel RM, Peter HH, Köhler G, Eibel H. Non-tolerant B cells cause autoimmunity in anti-CD8 IgG2a-transgenic mice. European Journal of Immunology. 26: 250-8. PMID 8566075 DOI: 10.1002/Eji.1830260139  0.484
1996 Battegay M, Bachmann MF, Burhkart C, Viville S, Benoist C, Mathis D, Hengartner H, Zinkernagel RM. Antiviral immune responses of mice lacking MHC class II or its associated invariant chain. Cellular Immunology. 167: 115-21. PMID 8548834 DOI: 10.1006/Cimm.1996.0014  0.695
1996 Zinkernagel RM. Immunology taught by viruses. Science (New York, N.Y.). 271: 173-8. PMID 8539616 DOI: 10.1126/Science.271.5246.173  0.57
1996 Moskophidis D, Zinkernagel* RM. Immunobiology of cytotoxic T-cell resistant virus variants: studies on lymphocytic choriomeningitis virus (LCMV) Seminars in Virology. 7: 3-11. DOI: 10.1006/SMVY.1996.0002  0.611
1995 van den Broek MF, Müller U, Huang S, Zinkernagel RM, Aguet M. Immune defence in mice lacking type I and/or type II interferon receptors. Immunological Reviews. 148: 5-18. PMID 8825279 DOI: 10.1111/J.1600-065X.1995.Tb00090.X  0.529
1995 Zinkernagel RM, Hengartner H. Viral immunopathology. Introduction. Springer Seminars in Immunopathology. 17: 119-20. PMID 8571163 DOI: 10.1007/BF00196160  0.551
1995 van den Broek MF, Kägi D, Zinkernagel RM, Hengartner H. Perforin dependence of natural killer cell-mediated tumor control in vivo. European Journal of Immunology. 25: 3514-6. PMID 8566046 DOI: 10.1002/eji.1830251246  0.682
1995 Bachmann MF, Hengartner H, Zinkernagel RM. T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction? European Journal of Immunology. 25: 3445-51. PMID 8566036 DOI: 10.1002/eji.1830251236  0.697
1995 Oxenius A, Bachmann MF, Ashton-Rickardt PG, Tonegawa S, Zinkernagel RM, Hengartner H. Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system. European Journal of Immunology. 25: 3402-11. PMID 8566030 DOI: 10.1002/Eji.1830251230  0.596
1995 Kägi D, Seiler P, Pavlovic J, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses. European Journal of Immunology. 25: 3256-62. PMID 8566009 DOI: 10.1002/eji.1830251209  0.704
1995 Steinhoff U, Müller U, Schertler A, Hengartner H, Aguet M, Zinkernagel RM. Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice. Journal of Virology. 69: 2153-8. PMID 7884863 DOI: 10.1128/Jvi.69.4.2153-2158.1995  0.591
1995 Roost HP, Bachmann MF, Haag A, Kalinke U, Pliska V, Hengartner H, Zinkernagel RM. Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity. Proceedings of the National Academy of Sciences of the United States of America. 92: 1257-61. PMID 7877965 DOI: 10.1073/Pnas.92.5.1257  0.631
1995 Hengel H, Burke K, Kyburz D, Zinkernagel RM, Koszinowski UH. Peptides control the gain and loss of allele specificity by mutated MHC class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 154: 4557-64. PMID 7722309  0.28
1995 Bachmann MF, Oxenius A, Pircher H, Hengartner H, Ashton-Richardt PA, Tonegawa S, Zinkernagel RM. TAP1-independent loading of class I molecules by exogenous viral proteins. European Journal of Immunology. 25: 1739-43. PMID 7615001 DOI: 10.1002/eji.1830250637  0.646
1995 Bachmann MF, Schorle H, Kühn R, Müller W, Hengartner H, Zinkernagel RM, Horak I. Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4. Journal of Virology. 69: 4842-6. PMID 7609051 DOI: 10.1128/Jvi.69.8.4842-4846.1995  0.551
1995 van den Broek MF, Müller U, Huang S, Aguet M, Zinkernagel RM. Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors. Journal of Virology. 69: 4792-6. PMID 7609046 DOI: 10.1128/Jvi.69.8.4792-4796.1995  0.544
1995 Hombach J, Pircher H, Tonegawa S, Zinkernagel RM. Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein. The Journal of Experimental Medicine. 182: 1615-9. PMID 7595234 DOI: 10.1084/jem.182.5.1615  0.51
1995 Zinkernagel RM. Immunosuppression by a noncytolytic virus via T cell mediated immunopathology. Implication for AIDS. Advances in Experimental Medicine and Biology. 374: 165-71. PMID 7572389 DOI: 10.1007/978-1-4615-1995-9_14  0.597
1995 Zinkernagel RM. The 1995 Albert Lasker Medical Research Award. MHC-restricted T-cell recognition. The basis of immune surveillance. Jama. 274: 1069-71. PMID 7563462  0.423
1995 Bachmann MF, Oxenius A, Mak TW, Zinkernagel RM. T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype. Journal of Immunology (Baltimore, Md. : 1950). 155: 3727-33. PMID 7561076  0.43
1995 Aichele P, Brduscha-Riem K, Zinkernagel RM, Hengartner H, Pircher H. T cell priming versus T cell tolerance induced by synthetic peptides. The Journal of Experimental Medicine. 182: 261-6. PMID 7540654 DOI: 10.1084/jem.182.1.261  0.604
1995 Freer G, Burkhart C, Rülicke T, Ghelardi E, Rohrer UH, Pircher H, Zinkernagel RM, Hengartner H. Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor beta chain transgenic mouse. European Journal of Immunology. 25: 1410-6. PMID 7539759 DOI: 10.1002/eji.1830250541  0.722
1995 Moskophidis D, Zinkernagel RM. Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus. Journal of Virology. 69: 2187-93. PMID 7533851 DOI: 10.1128/Jvi.69.4.2187-2193.1995  0.591
1995 Schulz M, Schuurman HJ, Joergensen J, Steiner C, Meerloo T, Kägi D, Hengartner H, Zinkernagel RM, Schreier MH, Bürki K. Acute rejection of vascular heart allografts by perforin-deficient mice. European Journal of Immunology. 25: 474-80. PMID 7533086 DOI: 10.1002/Eji.1830250225  0.617
1995 Moskophidis D, Battegay M, van den Broek M, Laine E, Hoffmann-Rohrer U, Zinkernagel RM. Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus. The Journal of General Virology. 76: 381-91. PMID 7531218 DOI: 10.1099/0022-1317-76-2-381  0.568
1995 Zinkernagel RM. Are HIV-specific CTL responses salutary or pathogenic? Current Opinion in Immunology. 7: 462-70. PMID 7495509 DOI: 10.1016/0952-7915(95)80089-1  0.526
1995 Kägi D, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. Lymphocyte-mediated cytotoxicity in vitro and in vivo: mechanisms and significance. Immunological Reviews. 146: 95-115. PMID 7493763 DOI: 10.1111/J.1600-065X.1995.Tb00686.X  0.538
1995 Gilfillan S, Bachmann M, Trembleau S, Adorini L, Kalinke U, Zinkernagel R, Benoist C, Mathis D. Efficient immune responses in mice lacking N-region diversity. European Journal of Immunology. 25: 3115-22. PMID 7489751 DOI: 10.1002/Eji.1830251119  0.542
1995 Altaner C, Braciale TJ, Cernescu C, Doherty P, Ertl HCJ, Gelman IH, Hilleman MR, Laughlin CA, Liu MA, Shoshkes Reiss C, Talbot P, Yewdell JW, Bennick J, Zinkernagel R. What are the major goals of research in viral immunology? Viral Immunology. 8: 175-180.  0.49
1995 Altaner C, Braciale TJ, Cernescu C, Doherty P, Ertl HCJ, Gelman IH, Hilleman MR, Laughlin CA, Liu MA, Shoshkes Reiss C, Talbot P, Yewdell JW, Zinkernagel R. Is immunization with naked DNA the most important factor in the development of vaccines? Viral Immunology. 8: 193-197.  0.471
1995 Altaner C, Braciale TJ, Cernescu C, Doherty P, Ertl HCJ, Gelman IH, George J, Hilleman MR, Laughlin CA, Shoshkes Reiss C, Talbot P, Yewdell JW, Zinkernagel R. How does a viral infection trigger an autoimmune disease? Viral Immunology. 8: 187-192.  0.537
1995 Altaner C, Braciale TJ, Cernescu C, Doherty P, Ertl HCJ, Gelman IH, Hilleman MR, Laughlin CA, Liu MA, Shoshkes Reiss C, Talbot P, Yewdell JW, Zinkernagel R. What is the most important achievement in viral immunology in the last five years? Viral Immunology. 8: 181-185.  0.5
1994 Aichele P, Kyburz D, Ohashi PS, Odermatt B, Zinkernagel RM, Hengartner H, Pircher H. Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America. 91: 444-8. PMID 8290546 DOI: 10.1073/Pnas.91.2.444  0.669
1994 Moskophidis D, Lechner F, Hengartner H, Zinkernagel RM. MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice. Journal of Immunology (Baltimore, Md. : 1950). 152: 4976-83. PMID 8176216  0.668
1994 Kägi D, Ledermann B, Bürki K, Seiler P, Odermatt B, Olsen KJ, Podack ER, Zinkernagel RM, Hengartner H. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature. 369: 31-7. PMID 8164737 DOI: 10.1038/369031A0  0.714
1994 Kopf M, Baumann H, Freer G, Freudenberg M, Lamers M, Kishimoto T, Zinkernagel R, Bluethmann H, Köhler G. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature. 368: 339-42. PMID 8127368 DOI: 10.1038/368339A0  0.478
1994 Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S. Evidence for a differential avidity model of T cell selection in the thymus. Cell. 76: 651-63. PMID 8124708 DOI: 10.1016/0092-8674(94)90505-3  0.502
1994 Lindemann D, Wilhelm R, Renard P, Althage A, Zinkernagel R, Mous J. Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene. The Journal of Experimental Medicine. 179: 797-807. PMID 8113676 DOI: 10.1084/JEM.179.3.797  0.574
1994 Moskophidis D, Battegay M, Bruendler MA, Laine E, Gresser I, Zinkernagel RM. Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon. Journal of Virology. 68: 1951-5. PMID 8107255 DOI: 10.1128/Jvi.68.3.1951-1955.1994  0.415
1994 Bachmann MF, Kündig TM, Freer G, Li Y, Kang CY, Bishop DH, Hengartner H, Zinkernagel RM. Induction of protective cytotoxic T cells with viral proteins. European Journal of Immunology. 24: 2228-36. PMID 8088338 DOI: 10.1002/eji.1830240944  0.727
1994 Müller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Aguet M. Functional role of type I and type II interferons in antiviral defense. Science (New York, N.Y.). 264: 1918-21. PMID 8009221 DOI: 10.1126/Science.8009221  0.456
1994 Zinkernagel RM. The role of antigen in maintaining T cell memory. Developments in Biological Standardization. 82: 189-91. PMID 7958474  0.434
1994 Bachmann MF, Bast C, Hengartner H, Zinkernagel RM. Immunogenicity of a viral model vaccine after different inactivation procedures. Medical Microbiology and Immunology. 183: 95-104. PMID 7935164 DOI: 10.1007/Bf00277160  0.639
1994 Bachmann MF, Kündig TM, Odermatt B, Hengartner H, Zinkernagel RM. Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells. Journal of Immunology (Baltimore, Md. : 1950). 153: 3386-97. PMID 7930564  0.577
1994 Bachmann MF, Kündig TM, Hengartner H, Zinkernagel RM. Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen. European Journal of Immunology. 24: 2567-70. PMID 7925584 DOI: 10.1002/eji.1830241046  0.671
1994 Oehen SU, Ohashi PS, Bürki K, Hengartner H, Zinkernagel RM, Aichele P. Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels. Cellular Immunology. 158: 342-52. PMID 7923387 DOI: 10.1006/cimm.1994.1281  0.668
1994 Rahemtulla A, Kündig TM, Narendran A, Bachmann MF, Julius M, Paige CJ, Ohashi PS, Zinkernagel RM, Mak TW. Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice. European Journal of Immunology. 24: 2213-8. PMID 7916297 DOI: 10.1002/Eji.1830240942  0.562
1994 Zinkernagel RM, Hengartner H. T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS. Immunology Today. 15: 262-8. PMID 7915115 DOI: 10.1016/0167-5699(94)90005-1  0.67
1994 Battegay M, Moskophidis D, Rahemtulla A, Hengartner H, Mak TW, Zinkernagel RM. Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice. Journal of Virology. 68: 4700-4. PMID 7911534  0.642
1994 Freer G, Burkhart C, Ciernik I, Bachmann MF, Hengartner H, Zinkernagel RM. Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen. Journal of Virology. 68: 3650-5. PMID 7910641 DOI: 10.1128/Jvi.68.6.3650-3655.1994  0.697
1994 Steinhoff U, Burkhart C, Arnheiter H, Hengartner H, Zinkernagel R. Virus or a hapten-carrier complex can activate autoreactive B cells by providing linked T help. European Journal of Immunology. 24: 773-6. PMID 7907298 DOI: 10.1002/eji.1830240343  0.682
1994 Rahemtulla A, Shahinian A, Kundig T, Zinkernagel R, Mak TW. CD4 negative mice as a model for immunodeficiency. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 342: 57-8. PMID 7904347 DOI: 10.1098/RSTB.1993.0135  0.473
1994 Zinkernagel RM. Some general aspects of immunity to viruses. Vaccine. 12: 1493-4. PMID 7879411 DOI: 10.1016/0264-410X(94)90070-1  0.556
1994 Kägi D, Ledermann B, Bürki K, Hengartner H, Zinkernagel RM. CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. European Journal of Immunology. 24: 3068-72. PMID 7805735 DOI: 10.1002/eji.1830241223  0.703
1994 Bachmann MF, Rohrer UH, Steinhoff U, Bürki K, Skuntz S, Arnheiter H, Hengartner H, Zinkernagel RM. T helper cell unresponsiveness: rapid induction in antigen-transgenic and reversion in non-transgenic mice. European Journal of Immunology. 24: 2966-73. PMID 7805723 DOI: 10.1002/eji.1830241207  0.718
1994 Bachmann MF, Hengartner H, Zinkernagel RM. Immunization with recombinant protein: conditions for cytotoxic T cell and/or antibody induction. Medical Microbiology and Immunology. 183: 315-24. PMID 7596314 DOI: 10.1007/Bf00196682  0.658
1994 Burkhart C, Freer G, Steinhoff U, Li Y, Bishop DH, Zinkernagel RM, Hengartner H. Localization of T helper cell epitopes in the vesicular stomatitis virus: the nucleoprotein is responsible for serotype cross-reactive T help. Viral Immunology. 7: 103-11. PMID 7541205 DOI: 10.1089/vim.1994.7.103  0.705
1994 Allen PM, Zinkernagel RM. Promethean viruses? Nature. 369: 355-6. PMID 7515164 DOI: 10.1038/369355a0  0.316
1994 Bachmann MF, Kündig TM, Kalberer CP, Hengartner H, Zinkernagel RM. How many specific B cells are needed to protect against a virus? Journal of Immunology (Baltimore, Md. : 1950). 152: 4235-41. PMID 7512589  0.63
1994 Burkhart C, Freer G, Castro R, Adorini L, Wiesmüller KH, Zinkernagel RM, Hengartner H. Characterization of T-helper epitopes of the glycoprotein of vesicular stomatitis virus. Journal of Virology. 68: 1573-80. PMID 7508998 DOI: 10.1128/Jvi.68.3.1573-1580.1994  0.693
1993 Ohashi PS, Oehen S, Aichele P, Pircher H, Odermatt B, Herrera P, Higuchi Y, Buerki K, Hengartner H, Zinkernagel RM. Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha. Journal of Immunology (Baltimore, Md. : 1950). 150: 5185-94. PMID 8496610  0.596
1993 Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature. 362: 758-61. PMID 8469287 DOI: 10.1038/362758A0  0.626
1993 Zinkernagel RM, Hengartner H. [Model concepts on the development of so-called autoimmune diseases]. Therapeutische Umschau. Revue Thã©Rapeutique. 50: 66-70. PMID 8456417  0.516
1993 Huang S, Hendriks W, Althage A, Hemmi S, Bluethmann H, Kamijo R, Vilcek J, Zinkernagel RM, Aguet M. Immune response in mice that lack the interferon-gamma receptor. Science (New York, N.Y.). 259: 1742-5. PMID 8456301 DOI: 10.1126/Science.8456301  0.557
1993 Ohashi PS, Zinkernagel RM, Leuscher I, Hengartner H, Pircher H. Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection. International Immunology. 5: 131-8. PMID 8452813 DOI: 10.1093/intimm/5.2.131  0.632
1993 Kündig TM, Hengartner H, Zinkernagel RM. T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs. Journal of Immunology (Baltimore, Md. : 1950). 150: 2316-21. PMID 8450214  0.676
1993 Zinkernagel RM, Hengartner H. Contra: CD8+ T-cell-mediated suppression without 'suppressor' T cells? International Archives of Allergy and Immunology. 100: 8-11. PMID 8428169 DOI: 10.1159/000236380  0.721
1993 Castelmur I, DiPaolo C, Bachmann MF, Hengartner H, Zinkernagel RM, Kündig TM. Comparison of the sensitivity of in vivo and in vitro assays for detection of antiviral cytotoxic T cell activity. Cellular Immunology. 151: 460-6. PMID 8402949 DOI: 10.1006/cimm.1993.1254  0.615
1993 Rothe J, Lesslauer W, Lötscher H, Lang Y, Koebel P, Köntgen F, Althage A, Zinkernagel R, Steinmetz M, Bluethmann H. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature. 364: 798-802. PMID 8395024 DOI: 10.1038/364798a0  0.44
1993 Molina TJ, Bachmann MF, Kündig TM, Zinkernagel RM, Mak TW. Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions. Journal of Immunology (Baltimore, Md. : 1950). 151: 699-706. PMID 8393038  0.566
1993 Bachmann MF, Kündig TM, Kalberer CP, Hengartner H, Zinkernagel RM. Formalin inactivation of vesicular stomatitis virus impairs T-cell- but not T-help-independent B-cell responses. Journal of Virology. 67: 3917-22. PMID 8389912 DOI: 10.1128/Jvi.67.7.3917-3922.1993  0.699
1993 Zinkernagel RM. [Autoimmune diseases]. Immunitã¤T Und Infektion. 21: 7-9. PMID 8344696  0.23
1993 Kyburz D, Aichele P, Speiser DE, Hengartner H, Zinkernagel RM, Pircher H. T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides. European Journal of Immunology. 23: 1956-62. PMID 8344359 DOI: 10.1002/eji.1830230834  0.681
1993 Kyburz D, Speiser DE, Battegay M, Hengartner H, Zinkernagel RM. Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins. European Journal of Immunology. 23: 1540-5. PMID 8325330 DOI: 10.1002/eji.1830230722  0.697
1993 Zinkernagel RM. Immune protection vs. immunopathology vs. autoimmunity: a question of balance and of knowledge. Brain Pathology (Zurich, Switzerland). 3: 115-21. PMID 8293172 DOI: 10.1111/J.1750-3639.1993.Tb00735.X  0.511
1993 Moskophidis D, Laine E, Zinkernagel RM. Peripheral clonal deletion of antiviral memory CD8+ T cells. European Journal of Immunology. 23: 3306-11. PMID 8258345 DOI: 10.1002/Eji.1830231237  0.59
1993 Battegay M, Kyburz D, Hengartner H, Zinkernagel RM. Enhancement of disease by neutralizing antiviral antibodies in the absence of primed antiviral cytotoxic T cells. European Journal of Immunology. 23: 3236-41. PMID 8258339 DOI: 10.1002/eji.1830231229  0.726
1993 Kündig TM, Kalberer CP, Hengartner H, Zinkernagel RM. Vaccination with two different vaccinia recombinant viruses: long-term inhibition of secondary vaccination. Vaccine. 11: 1154-8. PMID 8249436 DOI: 10.1016/0264-410X(93)90079-D  0.633
1993 Bachmann MF, Rohrer UH, Kündig TM, Bürki K, Hengartner H, Zinkernagel RM. The influence of antigen organization on B cell responsiveness. Science (New York, N.Y.). 262: 1448-51. PMID 8248784 DOI: 10.1126/Science.8248784  0.659
1993 Kündig TM, Schorle H, Bachmann MF, Hengartner H, Zinkernagel RM, Horak I. Immune responses in interleukin-2-deficient mice. Science (New York, N.Y.). 262: 1059-61. PMID 8235625 DOI: 10.1126/Science.8235625  0.668
1993 Zinkernagel RM, Moskophidis D, Kündig T, Oehen S, Pircher H, Hengartner H. Effector T-cell induction and T-cell memory versus peripheral deletion of T cells. Immunological Reviews. 133: 199-223. PMID 8225368 DOI: 10.1111/J.1600-065X.1993.Tb01517.X  0.656
1993 Weibel D, Bründler MA, Zinkernagel RM, Battegay M. Analysis of neutralizing antibody specificities of different strains of lymphocytic choriomeningitis virus with strain-specific immune sera. Research in Virology. 144: 471-8. PMID 8140290 DOI: 10.1016/S0923-2516(06)80062-2  0.495
1993 Kündig TM, Bachmann MF, Lefrancois L, Puddington L, Hengartner H, Zinkernagel RM. Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells. Journal of Immunology (Baltimore, Md. : 1950). 150: 4450-6. PMID 8097755  0.598
1993 Pircher H, Brduscha K, Steinhoff U, Kasai M, Mizuochi T, Zinkernagel RM, Hengartner H, Kyewski B, Müller KP. Tolerance induction by clonal deletion of CD4+8+ thymocytes in vitro does not require dedicated antigen-presenting cells. European Journal of Immunology. 23: 669-74. PMID 8095457 DOI: 10.1002/eji.1830230315  0.687
1993 Battegay M, Moskophidis D, Waldner H, Bründler MA, Fung-Leung WP, Mak TW, Hengartner H, Zinkernagel RM. Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells. Journal of Immunology (Baltimore, Md. : 1950). 151: 5408-15. PMID 7693811  0.645
1993 Kündig TM, Castelmur I, Bachmann MF, Abraham D, Binder D, Hengartner H, Zinkernagel RM. Fewer protective cytotoxic T-cell epitopes than T-helper-cell epitopes on vesicular stomatitis virus. Journal of Virology. 67: 3680-3. PMID 7684471 DOI: 10.1128/Jvi.67.6.3680-3683.1993  0.678
1993 Kyburz D, Speiser DE, Aebischer T, Hengartner H, Zinkernagel RM. Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 150: 5051-8. PMID 7684417  0.686
1993 Zinkernagel RM. Protection and damage by antiviral immunity. Harvey Lectures. 89: 29-51. PMID 7622361  0.333
1993 Zinkernagel RM, Althage A. Antiviral protection by virus-immune cytotoxic T cells: infected target cells are lysed before infectious virus progeny is assembled. The Journal of Experimental Medicine. 145: 644-51. PMID 233908 DOI: 10.1084/JEM.145.3.644  0.534
1993 Moskophldis D, Lechner F, Plrcher H, Zinkernagel RM. Erratum: Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells (Nature (1993) 362 (758-761)) Nature. 364. DOI: 10.1038/364262A0  0.6
1993 Oehen S, Zinkernagel R. Response from Oehen and Zinkernagel Trends in Microbiology. 1: 41. DOI: 10.1016/0966-842X(93)90027-O  0.25
1992 Fung-Leung WP, Kündig TM, Zinkernagel RM, Mak TW. Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression. The Journal of Experimental Medicine. 174: 1425-9. PMID 1683893 DOI: 10.1084/JEM.174.6.1425  0.517
1992 Speiser DE, Kyburz D, Stübi U, Hengartner H, Zinkernagel RM. Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection. Journal of Immunology (Baltimore, Md. : 1950). 149: 972-80. PMID 1634779  0.664
1992 Zinkernagel RM, Hengartner H. T cells causing immunological disease: immunopathology or autoimmunity? Research in Immunology. 143: 310-3. PMID 1631413  0.606
1992 Althage A, Odermatt B, Moskophidis D, Kündig T, Hoffman-Rohrer U, Hengartner H, Zinkernagel RM. Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation. European Journal of Immunology. 22: 1803-12. PMID 1623925 DOI: 10.1002/Eji.1830220720  0.75
1992 Moskophidis D, Pircher H, Ciernik I, Odermatt B, Hengartner H, Zinkernagel RM. Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo. Journal of Virology. 66: 3661-8. PMID 1583725 DOI: 10.1128/Jvi.66.6.3661-3668.1992  0.71
1992 Speiser DE, Roosnek E, Jeannet M, Zinkernagel RM. T-cell immunoincompetence in allogeneic chimerism. The New England Journal of Medicine. 326: 1028-9. PMID 1545845 DOI: 10.1056/NEJM199204093261515  0.459
1992 Speiser DE, Pircher H, Ohashi PS, Kyburz D, Hengartner H, Zinkernagel RM. Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny. The Journal of Experimental Medicine. 175: 1277-83. PMID 1533241 DOI: 10.1084/Jem.175.5.1277  0.686
1992 Zinkernagel RM. Virus-induced acquired immune suppression by cytotoxic T cell-mediated immunopathology. Veterinary Microbiology. 33: 13-8. PMID 1481353 DOI: 10.1016/0378-1135(92)90031-N  0.629
1992 Zinkernagel RM, Pircher H, Ohashi PS, Hengartner H. T cells causing immunological disease. Springer Seminars in Immunopathology. 14: 105-13. PMID 1475738 DOI: 10.1007/BF00195288  0.677
1992 Oehen S, Ohashi PS, Aichele P, Bürki K, Hengartner H, Zinkernagel RM. Vaccination or tolerance to prevent diabetes. European Journal of Immunology. 22: 3149-53. PMID 1446706 DOI: 10.1002/eji.1830221218  0.66
1992 Zinkernagel RM. How can we stimulate the immune system in vivo? Developments in Biological Standardization. 77: 29-30. PMID 1426669  0.32
1992 Oehen S, Waldner H, Kündig TM, Hengartner H, Zinkernagel RM. Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen. The Journal of Experimental Medicine. 176: 1273-81. PMID 1402673 DOI: 10.1084/Jem.176.5.1273  0.664
1992 Zinkernagel RM, Hengartner H. Virally induced immunosuppression. Current Opinion in Immunology. 4: 408-12. PMID 1388842 DOI: 10.1016/S0952-7915(06)80031-2  0.732
1992 Buchmeier MJ, Zinkernagel RM. Immunodominant T cell epitope from signal sequence. Science (New York, N.Y.). 257: 1142. PMID 1380726 DOI: 10.1126/Science.257.5073.1142  0.48
1992 Battegay M, Oehen S, Schulz M, Hengartner H, Zinkernagel RM. Vaccination with a synthetic peptide modulates lymphocytic choriomeningitis virus-mediated immunopathology. Journal of Virology. 66: 1199-201. PMID 1370548 DOI: 10.1128/Jvi.66.2.1199-1201.1992  0.636
1992 Speiser DE, Stübi U, Zinkernagel RM. Extrathymic positive selection of alpha beta T-cell precursors in nude mice. Nature. 355: 170-2. PMID 1346064 DOI: 10.1038/355170a0  0.514
1992 Kündig TM, Althage A, Hengartner H, Zinkernagel RM. Skin test to assess virus-specific cytotoxic T-cell activity. Proceedings of the National Academy of Sciences of the United States of America. 89: 7757-61. PMID 1323850 DOI: 10.1073/Pnas.89.16.7757  0.677
1992 Pircher H, Rebaï N, Groettrup M, Grégoire C, Speiser DE, Happ MP, Palmer E, Zinkernagel RM, Hengartner H, Malissen B. Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody. European Journal of Immunology. 22: 399-404. PMID 1311260 DOI: 10.1002/eji.1830220217  0.6
1992 Zinkernagel RM, Lambert PH. Immunity to infection Current Opinion in Immunology. 4: 385-386. DOI: 10.1016/S0952-7915(06)80026-9  0.46
1991 Roost HP, Charan S, Zinkernagel RM. Analysis of the kinetics of antiviral memory T help in vivo: characterization of short-lived cross-reactive T help. European Journal of Immunology. 20: 2547-54. PMID 2176607 DOI: 10.1002/EJI.1830201204  0.582
1991 Leist TP, Zinkernagel RM. Treatment with anti-tumor necrosis factor alpha does not influence the immune pathological response against lymphocytic choriomeningitis virus. Cytokine. 2: 29-34. PMID 2129499 DOI: 10.1016/1043-4666(90)90040-Z  0.384
1991 Schulz M, Zinkernagel RM, Hengartner H. Peptide-induced antiviral protection by cytotoxic T cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 991-3. PMID 1992491 DOI: 10.1073/PNAS.88.3.991  0.681
1991 Battegay M, Cooper S, Althage A, Bänziger J, Hengartner H, Zinkernagel RM. Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. Journal of Virological Methods. 33: 191-8. PMID 1939506 DOI: 10.1016/0166-0934(91)90018-U  0.637
1991 Zinkernagel RM, Pircher HP, Ohashi P, Oehen S, Odermatt B, Mak T, Arnheiter H, Bürki K, Hengartner H. T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease. Immunological Reviews. 122: 133-71. PMID 1937540 DOI: 10.1111/J.1600-065X.1991.Tb00601.X  0.73
1991 Odermatt B, Eppler M, Leist TP, Hengartner H, Zinkernagel RM. Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure. Proceedings of the National Academy of Sciences of the United States of America. 88: 8252-6. PMID 1910175 DOI: 10.1073/PNAS.88.18.8252  0.737
1991 Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, Odermatt B, Malissen B, Zinkernagel RM, Hengartner H. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell. 65: 305-17. PMID 1901764 DOI: 10.1016/0092-8674(91)90164-T  0.72
1991 Moskophidis D, Frei K, Löhler J, Fontana A, Zinkernagel RM. Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon. Journal of Virology. 65: 1364-9. PMID 1899893 DOI: 10.1128/Jvi.65.3.1364-1369.1991  0.362
1991 Rahemtulla A, Fung-Leung WP, Schilham MW, Kündig TM, Sambhara SR, Narendran A, Arabian A, Wakeham A, Paige CJ, Zinkernagel RM. Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4. Nature. 353: 180-4. PMID 1832488 DOI: 10.1038/353180A0  0.428
1991 Leist TP, Meager A, Exley T, Zinkernagel RM. Evidence for a role of IFN gamma in control of Listeria monocytogenes in T cell deficient mice. Experientia. 47: 630-2. PMID 1829687 DOI: 10.1007/BF01949893  0.565
1991 Oehen S, Hengartner H, Zinkernagel RM. Vaccination for disease. Science (New York, N.Y.). 251: 195-8. PMID 1824801 DOI: 10.1126/SCIENCE.1824801  0.599
1991 Aebischer T, Moskophidis D, Rohrer UH, Zinkernagel RM, Hengartner H. In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 88: 11047-51. PMID 1722316 DOI: 10.1073/Pnas.88.24.11047  0.707
1991 Zinkernagel RM, Hengartner H. HIV. Games that viruses play. Nature. 354: 433-4. PMID 1721106 DOI: 10.1038/354433a0  0.512
1991 Pircher H, Rohrer UH, Moskophidis D, Zinkernagel RM, Hengartner H. Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature. 351: 482-5. PMID 1710780 DOI: 10.1038/351482A0  0.709
1991 Schulz M, Aichele P, Schneider R, Hansen TH, Zinkernagel RM, Hengartner H. Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide. European Journal of Immunology. 21: 1181-5. PMID 1709866 DOI: 10.1002/eji.1830210513  0.668
1991 Speiser DE, Brändle R, Lees RK, Schneider R, Zinkernagel RM, MacDonald HR. Neonatal tolerance to MIs-1a determinants: deletion or anergy of V beta 6+ T lymphocytes depending upon MHC compatibility of neonatally injected cells. International Immunology. 3: 127-34. PMID 1709047 DOI: 10.1093/INTIMM/3.2.127  0.492
1991 Oehen S, Hengartner H, Zinkernagel R. Recombinant vaccines. Lancet. 337: 1542. PMID 1675384 DOI: 10.1016/0140-6736(91)93228-2  0.455
1991 Titus RG, Müller I, Kimsey P, Cerny A, Behin R, Zinkernagel RM, Louis JA. Exacerbation of experimental murine cutaneous leishmaniasis with CD4+Leishmania major‐specific T cell lines or clones which secrete interferon‐γ and mediate parasite‐specific delayed‐type hypersensitivity European Journal of Immunology. 21: 559-567. PMID 1672641 DOI: 10.1002/Eji.1830210305  0.586
1991 Titus RG, Müller I, Kimsey P, Cerny A, Behin R, Zinkernagel RM, Louis JA. Exacerbation of experimental marine cutaneous leishmaniasis with CD4+ Leishmania major-specific T cell lines or clones which secrete interferon-γ and mediate parasite-specific delayed-type hypersensitivity * European Journal of Immunology. 21: 559-567.  0.518
1990 Leist TP, Kohler M, Zinkernagel RM. Impaired generation of anti-viral cytotoxicity against lymphocytic choriomeningitis and vaccinia virus in mice treated with CD4-specific monoclonal antibody. Scandinavian Journal of Immunology. 30: 679-86. PMID 2532394 DOI: 10.1111/j.1365-3083.1989.tb02476.x  0.572
1990 Speiser DE, Zürcher T, Ramseier H, Hengartner H, Staeheli P, Haller O, Zinkernagel RM. Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen. Proceedings of the National Academy of Sciences of the United States of America. 87: 2021-5. PMID 2308961 DOI: 10.1073/PNAS.87.5.2021  0.676
1990 Kohler M, Rüttner B, Cooper S, Hengartner H, Zinkernagel RM. Enhanced tumor susceptibility of immunocompetent mice infected with lymphocytic choriomeningitis virus. Cancer Immunology, Immunotherapy : Cii. 32: 117-24. PMID 2289203 DOI: 10.1007/BF01754208  0.63
1990 Rüedi E, Hengartner H, Zinkernagel RM. Immunosuppression in mice by lymphocytic choriomeningitis virus infection: time dependence during primary and absence of effects on secondary antibody responses. Cellular Immunology. 130: 501-12. PMID 2170031 DOI: 10.1016/0008-8749(90)90290-8  0.636
1990 Zinkernagel RM. Antiviral T-cell memory? Current Topics in Microbiology and Immunology. 159: 65-77. PMID 2161327 DOI: 10.1007/978-3-642-75244-5_4  0.521
1990 Zinkernagel RM, Cooper S, Chambers J, Lazzarini RA, Hengartner H, Arnheiter H. Virus-induced autoantibody response to a transgenic viral antigen. Nature. 345: 68-71. PMID 2158632 DOI: 10.1038/345068A0  0.721
1990 Hauser T, Frei K, Zinkernagel RM, Leist TP. Role of tumor necrosis factor in Listeria resistance of nude mice. Medical Microbiology and Immunology. 179: 95-104. PMID 2113160 DOI: 10.1007/BF00198530  0.359
1990 Ohashi PS, Pircher H, Bürki K, Zinkernagel RM, Hengartner H. Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities. Nature. 346: 861-3. PMID 1975427 DOI: 10.1038/346861a0  0.595
1990 Pircher H, Moskophidis D, Rohrer U, Bürki K, Hengartner H, Zinkernagel RM. Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature. 346: 629-33. PMID 1696684 DOI: 10.1038/346629A0  0.707
1990 Stitz L, Schmitz C, Binder D, Zinkernagel R, Paoletti E, Becht H. Characterization and immunological properties of influenza A virus nucleoprotein (NP): cell-associated NP isolated from infected cells or viral NP expressed by vaccinia recombinant virus do not confer protection. Journal of General Virology. 71: 1169-1179. PMID 1693165 DOI: 10.1099/0022-1317-71-5-1169  0.551
1990 Aichele P, Hengartner H, Zinkernagel RM, Schulz M. Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide. The Journal of Experimental Medicine. 171: 1815-20. PMID 1692084 DOI: 10.1084/JEM.171.5.1815  0.705
1990 Zinkernagel R. Virus-induced immunosuppression Immunology Today. 11: 261. DOI: 10.1016/0167-5699(90)90102-F  0.372
1989 Herrmann P, Schreier MH, Bazin H, Zinkernagel RM, Cerny A. Delayed type hypersensitivity (DTH) in anti-IgM-treated B cell-depleted mice: analysis of induction and effector phase. Immunobiology. 177: 382-9. PMID 3264265 DOI: 10.1016/S0171-2985(88)80006-8  0.577
1989 Cerny A, Zinkernagel RM, Groscurth P. Development of follicular dendritic cells in lymph nodes of B-cell-depleted mice. Cell and Tissue Research. 254: 449-54. PMID 3264209 DOI: 10.1007/BF00225818  0.489
1989 Zinkernagel RM. Virus-triggered AIDS: a T-cell-mediated immunopathology? Immunology Today. 9: 370-2. PMID 3076409 DOI: 10.1016/0167-5699(88)91235-2  0.635
1989 Cottagnoud P, Neftel KA, Hany M, Zinkernagel RM. Inhibition of HSV-1 and vaccinia virus replication by cephalosporin derivatives. Antiviral Research. 10: 59-70. PMID 2852920 DOI: 10.1016/0166-3542(88)90014-9  0.44
1989 Gobet R, Cerny A, Rüedi E, Hengartner H, Zinkernagel RM. The role of antibodies in natural and acquired resistance of mice to vesicular stomatitis virus. Experimental Cell Biology. 56: 175-80. PMID 2849570 DOI: 10.1159/000163477  0.627
1989 Leist T, Althage A, Haenseler E, Hengartner H, Zinkernagel RM. Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated. The Journal of Experimental Medicine. 170: 269-77. PMID 2746160 DOI: 10.1084/JEM.170.1.269  0.668
1989 Zinkernagel RM, Pircher HP, Schulz M, Leist T, Oehen S, Hengartner H. Reactivity and tolerance of virus-specific T cells. Cold Spring Harbor Symposia On Quantitative Biology. 54: 843-51. PMID 2701218 DOI: 10.1101/SQB.1989.054.01.098  0.702
1989 Müller C, Kägi D, Aebischer T, Odermatt B, Held W, Podack ER, Zinkernagel RM, Hengartner H. Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus. European Journal of Immunology. 19: 1253-9. PMID 2668013 DOI: 10.1002/Eji.1830190716  0.668
1989 Pircher H, Bürki K, Lang R, Hengartner H, Zinkernagel RM. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature. 342: 559-61. PMID 2573841 DOI: 10.1038/342559a0  0.705
1989 Frei K, Malipiero UV, Leist TP, Zinkernagel RM, Schwab ME, Fontana A. On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases. European Journal of Immunology. 19: 689-94. PMID 2543584 DOI: 10.1002/eji.1830190418  0.501
1989 Leist TP, Eppler M, Zinkernagel RM. Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-gamma interferon-treated mice. Journal of Virology. 63: 2813-9. PMID 2542591 DOI: 10.1128/JVI.63.6.2813-2819.1989  0.493
1989 Speiser DE, Schneider R, Hengartner H, MacDonald HR, Zinkernagel RM. Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa. The Journal of Experimental Medicine. 170: 595-600. PMID 2526850 DOI: 10.1084/Jem.170.2.595  0.643
1989 MacDonald HR, Glasebrook AL, Schneider R, Lees RK, Pircher H, Pedrazzini T, Kanagawa O, Nicolas J, Howe RC, Zinkernagel RM, Hengartner H. T-cell reactivity and tolerance to Mlsa-encoded antigens. Immunological Reviews. 107: 89-108. PMID 2522087 DOI: 10.1111/J.1600-065X.1989.Tb00004.X  0.686
1989 MacDonald HR, Speiser D, Lees R, Schneider R, Zinkernagel RM, Hengartner H. Positive and negative selection of the T-cell antigen receptor repertoire in nontransgenic mice. Cold Spring Harbor Symposia On Quantitative Biology. 54: 129-33. PMID 2517917 DOI: 10.1101/Sqb.1989.054.01.016  0.658
1989 Speiser DE, Lees RK, Hengartner H, Zinkernagel RM, MacDonald HR. Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus. The Journal of Experimental Medicine. 170: 2165-70. PMID 2511269 DOI: 10.1084/Jem.170.6.2165  0.627
1989 Schulz M, Aichele P, Vollenweider M, Bobe FW, Cardinaux F, Hengartner H, Zinkernagel RM. Major histocompatibility complex--dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease. European Journal of Immunology. 19: 1657-67. PMID 2477254 DOI: 10.1002/eji.1830190921  0.707
1989 Rüedi E, Sykes M, Ildstad ST, Chester CH, Althage A, Hengartner H, Sachs DH, Zinkernagel RM. Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras. Cellular Immunology. 121: 185-95. PMID 2470518 DOI: 10.1016/0008-8749(89)90016-6  0.718
1989 Hany M, Oehen S, Schulz M, Hengartner H, Mackett M, Bishop DH, Overton H, Zinkernagel RM. Anti-viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunization with vaccinia-recombinant virus expressing LCMV-WE nucleoprotein or glycoprotein. European Journal of Immunology. 19: 417-24. PMID 2468501 DOI: 10.1002/eji.1830190302  0.675
1989 Stitzl L, Zinkernagel R. elimination of CD4+ T cells prevents fetal allograft rejection in mice after LCMV virus infection Journal of Reproductive Immunology. 15: 162. DOI: 10.1016/0165-0378(89)90329-X  0.514
1989 Pircher H, Mak TW, Lang R, Ballhausen W, Rüedi E, Hengartner H, Zinkernagel RM, Bürki K. T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. The Embo Journal. 8: 719-727. DOI: 10.1002/j.1460-2075.1989.tb03431.x  0.681
1988 Leist TP, Frei K, Kam-Hansen S, Zinkernagel RM, Fontana A. Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients. The Journal of Experimental Medicine. 167: 1743-8. PMID 3367098 DOI: 10.1084/JEM.167.5.1743  0.416
1988 Stitz L, Hengartner H, Althage A, Zinkernagel RM. An easy and rapid method to screen large numbers of antibodies against internal cellular determinants. Journal of Immunological Methods. 106: 211-6. PMID 3276792 DOI: 10.1016/0022-1759(88)90199-8  0.398
1988 Baenziger J, Hengartner H, Zinkernagel RM, Groscurth P. Distinct patterns of virus-specific T cell-mediated cytolysis of transformed versus primary target cells. Scandinavian Journal of Immunology. 28: 411-23. PMID 3264082 DOI: 10.1111/j.1365-3083.1988.tb01470.x  0.582
1988 MacDonald HR, Lees RK, Schneider R, Zinkernagel RM, Hengartner H. Positive selection of CD4+ thymocytes controlled by MHC class II gene products. Nature. 336: 471-3. PMID 3264054 DOI: 10.1038/336471a0  0.653
1988 Hengartner H, Odermatt B, Schneider R, Schreyer M, Wälle G, MacDonald HR, Zinkernagel RM. Deletion of self-reactive T cells before entry into the thymus medulla. Nature. 336: 388-90. PMID 3264053 DOI: 10.1038/336388a0  0.675
1988 Cerny A, Sutter S, Bazin H, Hengartner H, Zinkernagel RM. Clearance of lymphocytic choriomeningitis virus in antibody- and B-cell-deprived mice. Journal of Virology. 62: 1803-7. PMID 3258641 DOI: 10.1128/JVI.62.5.1803-1807.1988  0.65
1988 Leist TP, Heuchel R, Zinkernagel RM. Increased bactericidal macrophage activity induced by immunological stimuli is dependent on interferon (IFN)-gamma. Interference of anti-IFN-gamma but not anti-IFN-alpha/beta with modulation of macrophage activity caused by lymphocytic choriomeningitis virus infection or systemic graft-vs.-host reactions. European Journal of Immunology. 18: 1295-8. PMID 3138138 DOI: 10.1002/EJI.1830180822  0.492
1988 Frei K, Leist TP, Meager A, Gallo P, Leppert D, Zinkernagel RM, Fontana A. Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients. The Journal of Experimental Medicine. 168: 449-53. PMID 3135367 DOI: 10.1084/JEM.168.1.449  0.536
1988 Cerny A, Hügin AW, Bazin H, Sutter S, Hengartner H, Zinkernagel RM. Anti-Listeria monocytogenes immunity in mu-suppressed mice: a comparison of treatment with conventional hyperimmune rabbit anti-mouse IgM and affinity-purified, monoclonal rat anti-mouse IgM. Medical Microbiology and Immunology. 177: 123-31. PMID 3134601 DOI: 10.1007/BF00232892  0.598
1988 MacDonald HR, Schneider R, Lees RK, Howe RC, Acha-Orbea H, Festenstein H, Zinkernagel RM, Hengartner H. T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens. Nature. 332: 40-5. PMID 3126397 DOI: 10.1038/332040A0  0.639
1988 MacDonald HR, Howe RC, Pedrazzini T, Lees RK, Budd RC, Schneider R, Liao NS, Zinkernagel RM, Louis JA, Raulet DH. T-cell lineages, repertoire selection and tolerance induction Immunological Reviews. 104: 157-182. PMID 3049315 DOI: 10.1111/J.1600-065X.1988.Tb00762.X  0.519
1988 Manzionna MM, Seger RA, Wahn V, Zinkernagel RM, Böcker A, Hitzig WH. Absence of complement receptor type 3 and lymphocyte function antigen 1 causing deficient phagocyte and lymphocyte functions. European Journal of Pediatrics. 148: 58-61. PMID 2973988 DOI: 10.1007/BF00441816  0.351
1988 Zinkernagel RM, Rüedi E, Althage A, Hengartner H, Reimann G. Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells. The Journal of Experimental Medicine. 168: 1187-92. PMID 2971754 DOI: 10.1084/JEM.168.3.1187  0.733
1988 Leist TP, Rüedi E, Zinkernagel RM. Virus-triggered immune suppression in mice caused by virus-specific cytotoxic T cells. The Journal of Experimental Medicine. 167: 1749-54. PMID 2966846 DOI: 10.1084/JEM.167.5.1749  0.61
1988 Schulz M, Lienhard G, Rupp F, Zinkernagel RM, Hengartner H. Expression of T cell receptor gamma-chain in murine cytotoxic T cells: analysis of a highly transcribed nonrearranged gene cluster. Experimental Cell Biology. 56: 181-9. PMID 2849571 DOI: 10.1159/000163478  0.735
1988 Roost H, Charan S, Gobet R, Rüedi E, Hengartner H, and AAA, Zinkernagel RM. An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus. European Journal of Immunology. 18: 511-518. PMID 2452742 DOI: 10.1002/Eji.1830180404  0.725
1988 Schulz M, Lienhard G, Rupp F, Zinkernagel RM, Hengartner H. Expression of T cell receptor γ-chain in murine cytotoxic T cells: Analysis of a highly transcribed nonrearranged gene cluster Pathobiology. 56: 181-189. DOI: 10.1159/000163478  0.664
1987 Leist TP, Aguet M, Hässig M, Pevear DC, Pfau CJ, Zinkernagel RM. Lack of correlation between serum titres of interferon alpha, beta, natural killer cell activity and clinical susceptibility in mice infected with two isolates of lymphocytic choriomeningitis virus. The Journal of General Virology. 2213-8. PMID 3612089 DOI: 10.1099/0022-1317-68-8-2213  0.495
1987 Huegin AW, Cerny A, Zinkernagel RM, Neftel KA. Suppressive effects of B-lactam-antibiotics on in vitro generation of cytotoxic T-cells. International Journal of Immunopharmacology. 8: 723-9. PMID 3536767 DOI: 10.1016/0192-0561(86)90008-1  0.521
1987 Pircher H, Baenziger J, Schilham M, Sado T, Kamisaku H, Hengartner H, Zinkernagel RM. Characterization of virus-specific cytotoxic T cell clones from allogeneic bone marrow chimeras European Journal of Immunology. 17: 159-166. PMID 3493906 DOI: 10.1002/eji.1830170202  0.632
1987 Rupp F, Brecher J, Giedlin MA, Mosmann T, Zinkernagel RM, Hengartner H, Joho RH. T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes. Proceedings of the National Academy of Sciences of the United States of America. 84: 219-22. PMID 3491990 DOI: 10.1073/Pnas.84.1.219  0.753
1987 Pircher H, Michalopoulos EE, Iwamoto A, Ohashi PS, Baenziger J, Hengartner H, Zinkernagel RM, Mak TW. Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new V(α) family European Journal of Immunology. 17: 1843-1846. PMID 2961577 DOI: 10.1002/Eji.1830171226  0.576
1987 Charan S, Hengartner H, Zinkernagel RM. Antibodies against the two serotypes of vesicular stomatitis virus measured by enzyme-linked immunosorbent assay: immunodominance of serotype-specific determinants and induction of asymmetrically cross-reactive antibodies. Journal of Virology. 61: 2509-14. PMID 2439706 DOI: 10.1128/JVI.61.8.2509-2514.1987  0.597
1987 Zinkernagel R, Lagrange P. Regulation of Immune Response to Infectious Agents International Archives of Allergy and Immunology. 83: 1-13. DOI: 10.1159/000234385  0.322
1986 Cerny A, Hügin AW, Sutter S, Heusser CH, Bos N, Izui S, Hengartner H, Zinkernagel RM. Suppression of B cell development and antibody responses in mice with polyclonal rabbit and monoclonal rat anti-IgM antibodies. I. Characterization of the suppressed state. Experimental Cell Biology. 53: 301-13. PMID 3908182 DOI: 10.1159/000163327  0.423
1986 Zinkernagel RM, Leist T, Hengartner H, Althage A. Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D. The Journal of Experimental Medicine. 162: 2125-41. PMID 3877779 DOI: 10.1084/JEM.162.6.2125  0.639
1986 Zinkernagel RM. Biological role of major transplantation antigens in T cell self-recognition. Experientia. 42: 970-2. PMID 3530799 DOI: 10.1007/BF01940698  0.454
1986 Zinkernagel RM, Leist T, Hengartner H, Pestalozzi B, Stitz L. Studies on immunity to lymphocytic choriomeningitis virus. Medical Microbiology and Immunology. 175: 209-11. PMID 3523184 DOI: 10.1007/BF02122453  0.61
1986 Cerny A, Heusser C, Sutter S, Huegin AW, Bazin H, Hengartner H, Zinkernagel RM. Generation of agammaglobulinaemic mice by prenatal and postnatal exposure to polyclonal or monoclonal anti-IgM antibodies. Scandinavian Journal of Immunology. 24: 437-45. PMID 3489985 DOI: 10.1111/j.1365-3083.1986.tb02132.x  0.596
1986 Zinkernagel RM, Haenseler E, Leist T, Cerny A, Hengartner H, Althage A. T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay? The Journal of Experimental Medicine. 164: 1075-92. PMID 3489805 DOI: 10.1084/JEM.164.4.1075  0.666
1986 Cerny A, Huegin AW, Sutter S, Bazin H, Hengartner HH, Zinkernagel RM. Immunity to lymphocytic choriomeningitis virus in B cell-depleted mice: evidence for B cell and antibody-independent protection by memory T cells. European Journal of Immunology. 16: 913-7. PMID 3488911 DOI: 10.1002/EJI.1830160807  0.632
1986 Baenziger J, Hengartner H, Zinkernagel RM. Cloned cytotoxic T cells specific for lymphocytic choriomeningitis virus induce acute disease and primary footpad swelling in infected mice Medical Microbiology and Immunology. 175: 201-203. PMID 3487709 DOI: 10.1007/BF02122451  0.7
1986 Hügin AW, Cerny A, Wrann M, Hengartner H, Zinkernagel RM. Effect of cyclosporin A on immunity to Listeria monocytogenes. Infection and Immunity. 52: 12-7. PMID 3485573 DOI: 10.1128/IAI.52.1.12-17.1986  0.417
1986 Zinkernagel RM. Major histocompatibility gene complex-disease associations may reflect T cell-mediated immunopathology. European Journal of Clinical Investigation. 16: 101-5. PMID 3089803 DOI: 10.1111/j.1365-2362.1986.tb01315.x  0.394
1986 Fontana A, Erb P, Pircher H, Zinkernagel R, Weber E, Fierz W. Astrocytes as antigen-presenting cells. Part II: Unlike H-2K-dependent cytotoxic T cells, H-2Ia-restricted T cells are only stimulated in the presence of interferon-gamma. Journal of Neuroimmunology. 12: 15-28. PMID 3086381 DOI: 10.1016/0165-5728(86)90093-7  0.576
1986 Baenziger J, Hengartner H, Zinkernagel RM, Cole GA. Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus European Journal of Immunology. 16: 387-393. PMID 3084281 DOI: 10.1002/EJI.1830160413  0.707
1986 Rosenthal KL, Zinkernagel RM, Hengartner H, Groscurth P, Dennert G, Takayesu D, Prevec L. Persistence of vesicular stomatitis virus in cloned interleukin-2-dependent natural killer cell lines Journal of Virology. 60: 539-547. PMID 3021987 DOI: 10.1128/JVI.60.2.539-547.1986  0.641
1986 Rupp F, Frech G, Hengartner H, Zinkernagel RM, Joho R. No functional gamma-chain transcripts detected in an alloreactive cytotoxic T-cell clone. Nature. 321: 876-8. PMID 3014341 DOI: 10.1038/321876a0  0.756
1986 Gupta SC, Hengartner H, Zinkernagel RM. Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model. Proceedings of the National Academy of Sciences of the United States of America. 83: 2604-8. PMID 3010314 DOI: 10.1073/PNAS.83.8.2604  0.684
1986 Charan S, Huegin AW, Cerny A, Hengartner H, Zinkernagel RM. Effects of cyclosporin A on humoral immune response and resistance against vesicular stomatitis virus in mice. Journal of Virology. 57: 1139-44. PMID 3005615 DOI: 10.1128/JVI.57.3.1139-1144.1986  0.652
1986 Pircher H, Groscurth P, Baumhütter S, Aguet M, Zinkernagel RM, Hengartner H. A monoclonal antibody against altered LFA-1 induces proliferation and lymphokine release of cloned T cells. European Journal of Immunology. 16: 172-81. PMID 2420606 DOI: 10.1002/Eji.1830160212  0.664
1985 Zinkernagel RM, Pfau CJ, Hengartner H, Althage A. Susceptibility to murine lymphocytic choriomeningitis maps to class I MHC genes--a model for MHC/disease associations. Nature. 316: 814-7. PMID 4033780 DOI: 10.1038/316814A0  0.685
1985 Zinkernagel RM, Hengartner H, Stitz L. On the role of viruses in the evolution of immune responses. British Medical Bulletin. 41: 92-7. PMID 3882192 DOI: 10.1093/OXFORDJOURNALS.BMB.A072033  0.65
1985 Stitz L, Huang RT, Hengartner H, Rott R, Zinkernagel RM. Cytotoxic T cell lysis of target cells fused with liposomes containing influenza virus haemagglutinin and neuraminidase. The Journal of General Virology. 1333-9. PMID 3874262 DOI: 10.1099/0022-1317-66-6-1333  0.661
1985 Huegin AW, Cerny A, Hengartner H, Zinkernagel RM. Suppression by cyclosporin A of murine T-cell-mediated immunity against viruses in vivo and in vitro. Cellular Immunology. 90: 464-73. PMID 2981641 DOI: 10.1016/0008-8749(85)90211-4  0.717
1985 Rupp F, Acha-Orbea H, Hengartner H, Zinkernagel R, Joho R. Identical V beta T-cell receptor genes used in alloreactive cytotoxic and antigen plus I-A specific helper T cells. Nature. 315: 425-7. PMID 2582268 DOI: 10.1038/315425a0  0.729
1985 Pircher H, Zinkernagel RM, Hengartner H. Inhibition of hapten-specific cytotoxic T cell recognition by monoclonal anti-hapten antibodies. European Journal of Immunology. 15: 228-35. PMID 2579821 DOI: 10.1002/EJI.1830150305  0.623
1985 Acha-Orbea H, Zinkernagel RM, Hengartner H. Cytotoxic T cell clone-specific monoclonal antibodies used to select clonotypic antigen-specific cytotoxic T cells. European Journal of Immunology. 15: 31-6. PMID 2578398 DOI: 10.1002/EJI.1830150107  0.646
1984 Pestalozzi BC, Zinkernagel RM. Graft-versus-host reactions in F1 hybrid mice: MHC-restriction-independent generalized depression of virus-specific cytotoxic T cell response. Immunobiology. 166: 308-17. PMID 6610629 DOI: 10.1016/S0171-2985(84)80048-0  0.445
1984 Zinkernagel RM, Sado T, Althage A, Kamisaku H. Anti-viral immune response of allogeneic irradiation bone marrow chimeras: cytotoxic T cell responsiveness depends upon H-2 combination and infectious agent. European Journal of Immunology. 14: 14-23. PMID 6198181 DOI: 10.1002/EJI.1830140104  0.533
1983 Zinkernagel RM. [Transplantation antigens: biological function and role as disease determinants]. Die Naturwissenschaften. 69: 537-8. PMID 6984136 DOI: 10.1007/BF00463499  0.404
1983 Zinkernagel RM. How to escape immune surveillance? Springer Seminars in Immunopathology. 5: 107-12. PMID 6821229 DOI: 10.1007/BF00201959  0.426
1983 Zinkernagel RM, Althage A. Assessment of some genetic non-MHC differences with GVHR-induced anti-listeria activity of macrophages. Immunogenetics. 16: 571-6. PMID 6763914 DOI: 10.1007/BF00372025  0.397
1983 Maestroni GJ, Pierpaoli W, Zinkernagel RM. Allogeneic H-2d leads to H-2b irradiation bone marrow chimeras: a) failure to transfer chimerism adoptively and b) immune reactivity of immunocompetent lymphocytes adoptively transferred to chimeras. Immunobiology. 164: 417-29. PMID 6603414 DOI: 10.1016/S0171-2985(83)80037-0  0.297
1983 Brenan M, Zinkernagel RM. Influence of one virus infection on a second concurrent primary in vivo antiviral cytotoxic T-cell response. Infection and Immunity. 41: 470-5. PMID 6192082 DOI: 10.1128/IAI.41.2.470-475.1983  0.533
1982 Zinkernagel RM, Callahan GN. Low responsiveness to Dk or Db plus vaccinia virus or to Kk plus lymphocytic choriomeningitis virus assessed by availability of D or K products. Tissue Antigens. 17: 507-17. PMID 6977890 DOI: 10.1111/J.1399-0039.1981.TB00738.X  0.593
1982 Doherty PC, Zinkernagel RM, Ramshaw IA, Grant CK. Rejection of allogeneic tumor cells growing in mouse cerebrospinal fluid. Functional analysis of the inflammatory process. Journal of Neuroimmunology. 1: 93-9. PMID 6799545 DOI: 10.1016/0165-5728(81)90011-4  0.566
1982 Zinkernagel RM. Selection of restriction specificities of virus-specific cytotoxic T cells in the thymus: no evidence for a crucial role of antigen-presenting cells. Journal of Experimental Medicine. 156: 1842-1847. PMID 6184436 DOI: 10.1084/Jem.156.6.1842  0.523
1982 Zinkernagel RM, Rosenthal KL. Experiments and speculation on antiviral specificity of T and B cells. Immunological Reviews. 58: 131-55. PMID 6171502 DOI: 10.1111/j.1600-065X.1981.tb00352.x  0.53
1981 Zinkernagel R. RECOGNITION BY T-LYMPHOCYTES: INFERENCES FROM FUNCTIONAL STUDIES Biochemical Society Transactions. 9: 61P-61P. DOI: 10.1042/bst009061p  0.387
1980 Kreeb G, Zinkernagel RM. Role of the H-2I region in the generation of an antiviral cytotoxic T-cell response in vitro. Cellular Immunology. 53: 285-97. PMID 6967766 DOI: 10.1016/0008-8749(80)90329-9  0.443
1980 Kreeb G, Zinkernagel RM. Virus-specific proliferative T-cell responses: parameters and specificity. Cellular Immunology. 53: 267-84. PMID 6967765 DOI: 10.1016/0008-8749(80)90328-7  0.502
1980 Zinkernagel RM, Kreeb G, Althage A. Lymphohemopoietic origin of the immunogenic, virus-antigen-presenting cells triggering anti-viral T-cell responses. Clinical Immunology and Immunopathology. 15: 565-76. PMID 6966204 DOI: 10.1016/0090-1229(80)90067-7  0.562
1980 Zinkernagel RM, Althage A, Waterfield E, Kindred B, Welsh RM, Callahan G, Pincetl P. Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts. Journal of Experimental Medicine. 151: 376-399. PMID 6965398 DOI: 10.1084/Jem.151.2.376  0.505
1980 Geiger B, Rosenthal KL, Klein J, Zinkernagel RM, Singer SJ. Selective and unidirectional membrane redistribution of an H-2 antigen with an antibody-clustered viral antigen: relationship to mechanisms of cytotoxic T-cell interactions. Proceedings of the National Academy of Sciences of the United States of America. 76: 4603-7. PMID 228303 DOI: 10.1073/Pnas.76.9.4603  0.544
1980 Zinkernagel RM. Review: cellular immune responses to intracellular parasites: role of the major histocompatibility gene complex and thymus in determining immune responsiveness and susceptibility to disease. Parasite Immunology. 1: 91-109. PMID 121771 DOI: 10.1111/j.1365-3024.1979.tb00698.x  0.344
1980 Zinkernagel RM, Doherty PC. MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Advances in Immunology. 27: 51-177. PMID 92183 DOI: 10.1016/S0065-2776(08)60262-X  0.665
1979 Zinkernagel RM, Althage A, Callahan G. Thymic reconstitution of nude F1 mice with one or both parental thymus grafts. Journal of Experimental Medicine. 150: 693-697. PMID 314490 DOI: 10.1084/Jem.150.3.693  0.552
1979 Zinkernagel RM. Major transplantation antigens in host responses to infection. Hospital Practice. 13: 83-92. PMID 312757 DOI: 10.1080/21548331.1978.11707372  0.459
1979 Croker BP, Zinkernagel RM, Dixon FJ. Natural cytotoxic cells in NZB mice: spontaneous in vivo and in vitro primed activity and structural characteristics. Clinical Immunology and Immunopathology. 12: 410-24. PMID 222522 DOI: 10.1016/0090-1229(79)90046-1  0.458
1979 Zinkernagel RM. Associations between major histocompatibility antigens and susceptibility to disease. Annual Review of Microbiology. 33: 201-13. PMID 115381 DOI: 10.1146/ANNUREV.MI.33.100179.001221  0.329
1979 Zinkernagel RM. Thymus and lymphohemopoietic cells: their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control. Immunological Reviews. 42: 224-70. PMID 83701 DOI: 10.1111/j.1600-065X.1978.tb00264.x  0.437
1979 Zinkernagel RM. Speculations on the role of major transplantation antigens in cell-mediated immunity against intracellular parasites. Current Topics in Microbiology and Immunology. 82: 113-38. PMID 83220 DOI: 10.1007/978-3-642-46388-4_4  0.398
1979 Zinkernagel RM. HLA and H-2 Nature. 280: 618-618. DOI: 10.1038/280618b0  0.238
1978 Zinkernagel RM, Klein PA, Klein J. Host-determined T cell fine specificity for self-H-2 in radiation bone-marrow chimeras of standard C57BL/6 (H-2(b)) mutantHz1 (H-2 (ba)), and F (1) mice. Immunogenetics. 7: 73-7. PMID 21302059 DOI: 10.1007/BF01843990  0.417
1978 Zinkernagel RM, Callahan GN, Althage A, Cooper S, Streilein JW, Klein J. The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help. Journal of Experimental Medicine. 147: 897-911. PMID 305460 DOI: 10.1084/Jem.147.3.897  0.615
1978 Zinkernagel RM, Callahan GN, Althage A, Cooper S, Klein PA, Klein J. On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? The Journal of Experimental Medicine. 147: 882-96. PMID 305459 DOI: 10.1084/Jem.147.3.882  0.572
1978 Zinkernagel RM. Thymus function and reconstitution of immunodeficiency. The New England Journal of Medicine. 298: 222. PMID 304177 DOI: 10.1056/nejm197801262980416  0.253
1978 Zinkernagel RM, Althage A, Cooper S, Kreeb G, Klein PA, Sefton B, Flaherty L, Stimpfling J, Shreffler D, Klein J. Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness. The Journal of Experimental Medicine. 148: 592-606. PMID 212503 DOI: 10.1084/Jem.148.2.592  0.508
1978 Zinkernagel RM, Adler B, Holland JJ. Cell-mediated immunity to vesicular stomatitis virus infections in mice. Experimental Cell Biology. 46: 53-70. PMID 202522 DOI: 10.1159/000162882  0.556
1978 Zinkernagel R, Althage A, Cooper S, Callahan G, Klein J. In irradiation chimeras, K or D regions of the chimeric host, not of the donor lymphocytes, determine immune responsiveness of antiviral cytotoxic T cells Journal of Experimental Medicine. 148: 805-810. PMID 100570 DOI: 10.1084/Jem.148.3.805  0.406
1978 Zinkernagel RM. The thymus: Its influence on recognition of “self major histocompatibility antigens” by T cells and consequences for reconstitution of immunodeficiency Springer Seminars in Immunopathology. 1: 405-415. DOI: 10.1007/BF01857313  0.472
1977 Perrin LH, Zinkernagel RM, Oldstone MBA. Immune response in humans after vaccination with vaccinia virus: generation of a virus-specific cytotoxic activity by human peripheral lymphocytes. Journal of Experimental Medicine. 146: 949-969. PMID 302316 DOI: 10.1084/Jem.146.4.949  0.582
1977 Zinkernagel RM, Doherty PC. The concept that surveillance of self is mediated via the same set of genes that determines recognition of allogenic cells. Cold Spring Harbor Symposia On Quantitative Biology. 505-10. PMID 302174 DOI: 10.1101/Sqb.1977.041.01.058  0.541
1977 Zinkernagel RM, Callahan GN, Streilein JW, Klein J. Neonatally tolerant mice fail to react against virus-infected tolerated cells. Nature. 266: 837-9. PMID 301251 DOI: 10.1038/266837A0  0.475
1977 Zinkernagel RM, Doherty PC. Major transplantation antigens, viruses, and specificity of surveillance T cells. Contemporary Topics in Immunobiology. 7: 179-220. PMID 69515 DOI: 10.1007/978-1-4684-3054-7_5  0.605
1977 Zinkernagel RM, Althage A, Adler B, Blanden RV, Davidson WF, Kees U, Dunlop MB, Shreffler DC. H-2 restriction of cell-mediated immunity to an intracellular bacterium: effector T cells are specific for Listeria antigen in association with H-21 region-coded self-markers. The Journal of Experimental Medicine. 145: 1353-67. PMID 67177 DOI: 10.1084/Jem.145.5.1353  0.59
1977 Zinkernagel RM, Klein J. H-2-associated specificity of virus-immune cytotoxic T cells fromH-2 mutant and wild-type mice: M523 (H-2K ka ) and M505(H-2K bd ) do, M504 (H-2D da ) and M506(H-2K fa ) do not crossreact with wild-typeH-2K orH-2D Immunogenetics. 4: 581-590. DOI: 10.1007/BF01575691  0.31
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