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Melvin I. Simon, Ph.D. - Publications

Affiliations: 
Biology California Institute of Technology, Pasadena, CA 
Area:
Signal Transduction
Website:
http://biology.caltech.edu/Members/Simon

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Simon M. RETROSPECTIVE. Alfred Gilman (1941-2015). Science (New York, N.Y.). 351: 566. PMID 26912691 DOI: 10.1126/Science.Aaf2848  0.331
2010 Bao XR, Fraser ID, Wall EA, Quake SR, Simon MI. Variability in G-protein-coupled signaling studied with microfluidic devices. Biophysical Journal. 99: 2414-22. PMID 20959081 DOI: 10.1016/J.Bpj.2010.08.043  0.63
2009 Wall EA, Zavzavadjian JR, Chang MS, Randhawa B, Zhu X, Hsueh RC, Liu J, Driver A, Bao XR, Sternweis PC, Simon MI, Fraser ID. Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105. Science Signaling. 2: ra28. PMID 19531803 DOI: 10.1126/Scisignal.2000202  0.648
2008 Slep KC, Kercher MA, Wieland T, Chen CK, Simon MI, Sigler PB. Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. Proceedings of the National Academy of Sciences of the United States of America. 105: 6243-8. PMID 18434540 DOI: 10.1073/Pnas.0801569105  0.387
2007 Shi G, Partida-Sánchez S, Misra RS, Tighe M, Borchers MT, Lee JJ, Simon MI, Lund FE. Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes. The Journal of Experimental Medicine. 204: 2705-18. PMID 17938235 DOI: 10.1084/Jem.20071267  0.318
2006 Burns ME, Mendez A, Chen CK, Almuete A, Quillinan N, Simon MI, Baylor DA, Chen J. Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1036-44. PMID 16421323 DOI: 10.1523/Jneurosci.3301-05.2006  0.366
2005 Quezada CM, Hamel DJ, Gradinaru C, Bilwes AM, Dahlquist FW, Crane BR, Simon MI. Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA. The Journal of Biological Chemistry. 280: 30581-5. PMID 15994328 DOI: 10.1074/Jbc.M505316200  0.756
2005 Hwang JI, Choi S, Fraser ID, Chang MS, Simon MI. Silencing the expression of multiple Gbeta-subunits eliminates signaling mediated by all four families of G proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 9493-8. PMID 15983374 DOI: 10.1073/Pnas.0503503102  0.399
2005 Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, ... ... Simon MI, et al. An open letter to Elias Zerhouni. Science (New York, N.Y.). 307: 1409-10. PMID 15746409 DOI: 10.1126/Science.307.5714.1409C  0.431
2004 Zhu X, Hart R, Chang MS, Kim JW, Lee SY, Cao YA, Mock D, Ke E, Saunders B, Alexander A, Grossoehme J, Lin KM, Yan Z, Hsueh R, Lee J, ... ... Simon MI, et al. Analysis of the major patterns of B cell gene expression changes in response to short-term stimulation with 33 single ligands. Journal of Immunology (Baltimore, Md. : 1950). 173: 7141-9. PMID 15585835 DOI: 10.4049/Jimmunol.173.12.7141  0.31
2004 Quezada CM, Gradinaru C, Simon MI, Bilwes AM, Crane BR. Helical shifts generate two distinct conformers in the atomic resolution structure of the CheA phosphotransferase domain from Thermotoga maritima. Journal of Molecular Biology. 341: 1283-94. PMID 15321722 DOI: 10.1016/J.Jmb.2004.06.061  0.753
2004 Hwang JI, Fraser ID, Choi S, Qin XF, Simon MI. Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 488-93. PMID 14699051 DOI: 10.1073/Pnas.0307549100  0.323
2003 Borchers MT, Biechele T, Justice JP, Ansay T, Cormier S, Mancino V, Wilkie TM, Simon MI, Lee NA, Lee JJ. Methacholine-induced airway hyperresponsiveness is dependent on Galphaq signaling. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L114-20. PMID 12611815 DOI: 10.1152/Ajplung.00322.2002  0.301
2003 Slice LW, Han SK, Simon MI. Galphaq signaling is required for Rho-dependent transcriptional activation of the cyclooxygenase-2 promoter in fibroblasts. Journal of Cellular Physiology. 194: 127-38. PMID 12494451 DOI: 10.1002/Jcp.10195  0.324
2003 Krispel CM, Chen CK, Simon MI, Burns ME. Prolonged Photoresponses and Defective Adaptation in Rods of Gβ5-/- Mice The Journal of Neuroscience. 23: 6965-6971. DOI: 10.1523/Jneurosci.23-18-06965.2003  0.35
2002 Han SK, Dong X, Hwang JI, Zylka MJ, Anderson DJ, Simon MI. Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 14740-5. PMID 12397184 DOI: 10.1073/Pnas.192565799  0.334
2002 Griswold IJ, Zhou H, Matison M, Swanson RV, McIntosh LP, Simon MI, Dahlquist FW. The solution structure and interactions of CheW from Thermotoga maritima. Nature Structural Biology. 9: 121-5. PMID 11799399 DOI: 10.1038/Nsb753  0.332
2002 Bilwes AM, Park SY, Quezada CM, Simon MI, Crane BR. Structure and Function of CheA, the Histidine Kinase Central to Bacterial Chemotaxis Histidine Kinases in Signal Transduction. 47-72. DOI: 10.1016/B978-012372484-7/50005-9  0.739
2001 Offermanns S, Negulescu P, Hu YH, Simon MI. Conditionally expressed G alpha 15 couples to endogenous receptors in GH3 cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 364: 140-8. PMID 11534853 DOI: 10.1007/S002100100444  0.339
2001 Bilwes AM, Quezada CM, Croal LR, Crane BR, Simon MI. Nucleotide binding by the histidine kinase CheA. Nature Structural Biology. 8: 353-60. PMID 11276258 DOI: 10.1038/86243  0.755
2000 Mendez A, Burns ME, Roca A, Lem J, Wu LW, Simon MI, Baylor DA, Chen J. Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron. 28: 153-64. PMID 11086991 DOI: 10.1016/S0896-6273(00)00093-3  0.327
2000 He W, Lu L, Zhang X, El-Hodiri HM, Chen CK, Slep KC, Simon MI, Jamrich M, Wensel TG. Modules in the photoreceptor RGS9-1.Gbeta 5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability. The Journal of Biological Chemistry. 275: 37093-100. PMID 10978345 DOI: 10.1074/Jbc.M006982200  0.367
2000 Yue C, Ku CY, Liu M, Simon MI, Sanborn BM. Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C. The Journal of Biological Chemistry. 275: 30220-5. PMID 10893237 DOI: 10.1074/Jbc.M004276200  0.351
2000 Wieland T, Bahtijari N, Zhou XB, Kleuss C, Simon MI. Polarity exchange at the interface of regulators of G protein signaling with G protein alpha-subunits. The Journal of Biological Chemistry. 275: 28500-6. PMID 10878019 DOI: 10.1074/Jbc.M004187200  0.376
2000 Satterthwaite AB, Willis F, Kanchanastit P, Fruman D, Cantley LC, Helgason CD, Humphries RK, Lowell CA, Simon M, Leitges M, Tarakhovsky A, Tedder TF, Lesche R, Wu H, Witte ON. A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 97: 6687-92. PMID 10829070 DOI: 10.1073/Pnas.110146697  0.337
2000 Tanaka J, Nakagawa S, Kushiya E, Yamasaki M, Fukaya M, Iwanaga T, Simon MI, Sakimura K, Kano M, Watanabe M. Gq protein alpha subunits Galphaq and Galpha11 are localized at postsynaptic extra-junctional membrane of cerebellar Purkinje cells and hippocampal pyramidal cells. The European Journal of Neuroscience. 12: 781-92. PMID 10762307 DOI: 10.1046/J.1460-9568.2000.00959.X  0.311
2000 Lyubarsky AL, Chen C, Simon MI, Pugh EN. Mice lacking G-protein receptor kinase 1 have profoundly slowed recovery of cone-driven retinal responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2209-17. PMID 10704496 DOI: 10.1523/Jneurosci.20-06-02209.2000  0.318
2000 Chen CK, Burns ME, He W, Wensel TG, Baylor DA, Simon MI. Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. Nature. 403: 557-60. PMID 10676965 DOI: 10.1038/35000601  0.355
2000 Kovoor A, Chen CK, He W, Wensel TG, Simon MI, Lester HA. Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins. The Journal of Biological Chemistry. 275: 3397-402. PMID 10652332 DOI: 10.1074/Jbc.275.5.3397  0.352
2000 Yu B, Gu L, Simon MI. Inhibition of subsets of G protein-coupled receptors by empty mutants of G protein alpha subunits in g(o), G(11), and G(16). The Journal of Biological Chemistry. 275: 71-6. PMID 10617587 DOI: 10.1074/Jbc.275.1.71  0.344
1999 Chen CK, Burns ME, Spencer M, Niemi GA, Chen J, Hurley JB, Baylor DA, Simon MI. Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 3718-22. PMID 10097103 DOI: 10.1073/Pnas.96.7.3718  0.543
1999 Bilwes AM, Alex LA, Crane BR, Simon MI. Structure of CheA, a signal-transducing histidine kinase. Cell. 96: 131-41. PMID 9989504 DOI: 10.1016/S0092-8674(00)80966-6  0.351
1998 Yu B, Simon MI. Interaction of the xanthine nucleotide binding Goalpha mutant with G protein-coupled receptors. The Journal of Biological Chemistry. 273: 30183-8. PMID 9804774 DOI: 10.1074/Jbc.273.46.30183  0.334
1998 Offermanns S, Simon MI. Genetic analysis of mammalian G-protein signalling. Oncogene. 17: 1375-81. PMID 9779985 DOI: 10.1038/Sj.Onc.1202173  0.384
1998 Mao J, Yuan H, Xie W, Simon MI, Wu D. Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors. The Journal of Biological Chemistry. 273: 27118-23. PMID 9765229 DOI: 10.1074/Jbc.273.42.27118  0.33
1998 Mao J, Xie W, Yuan H, Simon MI, Mano H, Wu D. Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13. The Embo Journal. 17: 5638-46. PMID 9755164 DOI: 10.1093/Emboj/17.19.5638  0.358
1998 Satpaev DK, Chen CK, Scotti A, Simon MI, Hurley JB, Slepak VZ. Autophosphorylation and ADP regulate the Ca2+-dependent interaction of recoverin with rhodopsin kinase. Biochemistry. 37: 10256-62. PMID 9665733 DOI: 10.1021/Bi9804986  0.533
1998 Usher KC, de la Cruz AF, Dahlquist FW, Swanson RV, Simon MI, Remington SJ. Crystal structures of CheY from Thermotoga maritima do not support conventional explanations for the structural basis of enhanced thermostability. Protein Science : a Publication of the Protein Society. 7: 403-12. PMID 9521117 DOI: 10.1002/Pro.5560070221  0.324
1998 Takeuchi T, Bottcher A, Quezada CM, Simon MI, Meade TJ, Gray HB. Selective inhibition of human α-thrombin by cobalt(III) Schiff base complexes [20] Journal of the American Chemical Society. 120: 8555-8556. DOI: 10.1021/Ja981191X  0.72
1997 Xu J, Dodd RL, Makino CL, Simon MI, Baylor DA, Chen J. Prolonged photoresponses in transgenic mouse rods lacking arrestin. Nature. 389: 505-9. PMID 9333241 DOI: 10.1038/39068  0.401
1997 Liu M, Yu B, Nakanishi O, Wieland T, Simon M. The Ca2+-dependent binding of calmodulin to an N-terminal motif of the heterotrimeric G protein β subunit Journal of Biological Chemistry. 272: 18801-18807. PMID 9228054 DOI: 10.1074/Jbc.272.30.18801  0.343
1997 Yu B, Slepak VZ, Simon MI. Characterization of a Goalpha mutant that binds xanthine nucleotides. The Journal of Biological Chemistry. 272: 18015-9. PMID 9218429 DOI: 10.1074/Jbc.272.29.18015  0.366
1997 Jiang M, Bourret RB, Simon MI, Volz K. Uncoupled phosphorylation and activation in bacterial chemotaxis. The 2.3 A structure of an aspartate to lysine mutant at position 13 of CheY. The Journal of Biological Chemistry. 272: 11850-5. PMID 9115243 DOI: 10.1074/Jbc.272.18.11850  0.347
1997 Wieland T, Chen CK, Simon MI. The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination. The Journal of Biological Chemistry. 272: 8853-6. PMID 9083000 DOI: 10.1074/Jbc.272.14.8853  0.307
1997 Offermanns S, Mancino V, Revel JP, Simon MI. Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science (New York, N.Y.). 275: 533-6. PMID 8999798 DOI: 10.1126/Science.275.5299.533  0.35
1997 Sanna MG, Simon MI. In vivo and in vitro characterization of Escherichia coli protein CheZ gain- and loss-of-function mutants. Journal of Bacteriology. 178: 6275-80. PMID 8892829 DOI: 10.1128/Jb.178.21.6275-6280.1996  0.391
1996 Quick MW, Lester HA, Davidson N, Simon MI, Aragay AM. Desensitization of inositol 1,4,5-trisphosphate/Ca2+-induced Cl- currents by prolonged activation of G proteins in Xenopus oocytes. The Journal of Biological Chemistry. 271: 32021-7. PMID 8943251 DOI: 10.1074/Jbc.271.50.32021  0.342
1996 Watson AJ, Aragay AM, Slepak VZ, Simon MI. A novel form of the G protein β subunit Gβ5 is specifically expressed in the vertebrate retina Journal of Biological Chemistry. 271: 28154-28160. PMID 8910430 DOI: 10.1074/Jbc.271.45.28154  0.356
1996 Offermanns S, Hu YH, Simon MI. Galpha12 and galpha13 are phosphorylated during platelet activation. The Journal of Biological Chemistry. 271: 26044-8. PMID 8824244 DOI: 10.1074/Jbc.271.42.26044  0.364
1996 Offermanns S, Iida-Klein A, Segre GV, Simon MI. G alpha q family members couple parathyroid hormone (PTH)/PTH-related peptide and calcitonin receptors to phospholipase C in COS-7 cells. Molecular Endocrinology. 10: 566-574. PMID 8732687 DOI: 10.1210/Mend.10.5.8732687  0.314
1996 Liu M, Simon MI. Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C Nature. 382: 83-87. PMID 8657310 DOI: 10.1038/382083A0  0.378
1996 Sanna MG, Simon MI. Isolation and in vitro characterization of CheZ suppressors for the Escherichia coli chemotactic response regulator mutant CheYN23D. The Journal of Biological Chemistry. 271: 7357-61. PMID 8631757 DOI: 10.1074/Jbc.271.13.7357  0.366
1996 Brundage L, Avery L, Katz A, Kim UJ, Mendel JE, Sternberg PW, Simon MI. Mutations in a C. elegans Gqalpha gene disrupt movement, egg laying, and viability. Neuron. 16: 999-1009. PMID 8630258 DOI: 10.1016/S0896-6273(00)80123-3  0.351
1996 Swanson RV, Sanna MG, Simon MI. Thermostable chemotaxis proteins from the hyperthermophilic bacterium Thermotoga maritima. Journal of Bacteriology. 178: 484-9. PMID 8550470 DOI: 10.1128/Jb.178.2.484-489.1996  0.387
1995 Bowie JU, Pakula AA, Simon MI. The three-dimensional structure of the aspartate receptor from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 51: 145-54. PMID 15299315 DOI: 10.1107/S0907444994010498  0.337
1995 Mendel JE, Korswagen HC, Liu KS, Hajdu-Cronin YM, Simon MI, Plasterk RH, Sternberg PW. Participation of the protein Go in multiple aspects of behavior in C. elegans. Science (New York, N.Y.). 267: 1652-5. PMID 7886455 DOI: 10.1126/Science.7886455  0.317
1995 Slepak VZ, Katz A, Simon MI. Functional analysis of a dominant negative mutant of Gαi2 Journal of Biological Chemistry. 270: 4037-4041. PMID 7876152 DOI: 10.1074/Jbc.270.8.4037  0.371
1995 Chen J, Makino CL, Peachey NS, Baylor DA, Simon MI. Mechanisms of rhodopsin inactivation in vivo as revealed by a COOH-terminal truncation mutant. Science (New York, N.Y.). 267: 374-7. PMID 7824934 DOI: 10.1126/Science.7824934  0.352
1995 Offermanns S, Simon MI. G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C. The Journal of Biological Chemistry. 270: 15175-80. PMID 7797501 DOI: 10.1074/Jbc.270.25.15175  0.302
1995 Wu D, Jiang H, Simon MI. Different alpha 1-adrenergic receptor sequences required for activating different G alpha subunits of Gq class of G proteins. The Journal of Biological Chemistry. 270: 9828-32. PMID 7730363 DOI: 10.1074/Jbc.270.17.9828  0.314
1995 Aragay AM, Collins LR, Post GR, Watson AJ, Feramisco JR, Brown JH, Simon MI. G12 requirement for thrombin-stimulated gene expression and DNA synthesis in 1321N1 astrocytoma cells. The Journal of Biological Chemistry. 270: 20073-7. PMID 7650024 DOI: 10.1074/Jbc.270.34.20073  0.339
1995 Sanna MG, Swanson RV, Bourret RB, Simon MI. Mutations in the chemotactic response regulator, CheY, that confer resistance to the phosphatase activity of CheZ. Molecular Microbiology. 15: 1069-79. PMID 7623663 DOI: 10.1111/J.1365-2958.1995.Tb02282.X  0.367
1995 Swanson RV, Lowry DF, Matsumura P, McEvoy MM, Simon MI, Dahlquist FW. Localized perturbations in CheY structure monitored by NMR identify a CheA binding interface. Nature Structural Biology. 2: 906-10. PMID 7552716 DOI: 10.1038/Nsb1095-906  0.641
1995 Xu J, Wu D, Slepak VZ, Simon MI. The N terminus of phosducin is involved in binding of βγ subunits of G protein Proceedings of the National Academy of Sciences of the United States of America. 92: 2086-2090. PMID 7534410 DOI: 10.1073/Pnas.92.6.2086  0.367
1994 Alex LA, Simon MI. Protein histidine kinases and signal transduction in prokaryotes and eukaryotes. Trends in Genetics : Tig. 10: 133-8. PMID 8029829 DOI: 10.1016/0168-9525(94)90215-1  0.325
1993 Jiang H, Wu D, Simon MI. The transforming activity of activated G alpha 12. Febs Letters. 330: 319-22. PMID 8397105 DOI: 10.1016/0014-5793(93)80896-3  0.318
1993 Bourret RB, Davagnino J, Simon MI. The carboxy-terminal portion of the CheA kinase mediates regulation of autophosphorylation by transducer and CheW. Journal of Bacteriology. 175: 2097-101. PMID 8384620 DOI: 10.1128/Jb.175.7.2097-2101.1993  0.413
1993 Schuster SC, Swanson RV, Alex LA, Bourret RB, Simon MI. Assembly and function of a quaternary signal transduction complex monitored by surface plasmon resonance. Nature. 365: 343-7. PMID 8377825 DOI: 10.1038/365343A0  0.351
1993 Wilkie TM, Chen Y, Gilbert DJ, Moore KJ, Yu L, Simon MI, Copeland NG, Jenkins NA. Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. Genomics. 18: 175-84. PMID 8288218 DOI: 10.1006/Geno.1993.1452  0.338
1993 Katz A, Wu D, Simon MI. Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C. Nature. 360: 686-9. PMID 1465134 DOI: 10.1038/360686A0  0.309
1992 von Weizsäcker E, Strathmann MP, Simon MI. Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA. Biochemical and Biophysical Research Communications. 183: 350-6. PMID 1543505 DOI: 10.1016/0006-291X(92)91650-F  0.342
1992 Pakula AA, Simon MI. Determination of transmembrane protein structure by disulfide cross-linking: the Escherichia coli Tar receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 4144-8. PMID 1315053 DOI: 10.1073/Pnas.89.9.4144  0.379
1992 Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI. Evolution of the mammalian G protein alpha subunit multigene family. Nature Genetics. 1: 85-91. PMID 1302014 DOI: 10.1038/Ng0592-85  0.378
1991 Strathmann M, Simon MI. G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates. Proceedings of the National Academy of Sciences of the United States of America. 87: 9113-7. PMID 2123549 DOI: 10.1073/Pnas.87.23.9113  0.338
1991 Borkovich KA, Simon MI. Coupling of receptor function to phosphate-transfer reactions in bacterial chemotaxis Methods in Enzymology. 200: 205-214. PMID 1956318 DOI: 10.1016/0076-6879(91)00140-R  0.37
1991 Lochrie MA, Mendel JE, Sternberg PW, Simon MI. Homologous and unique G protein alpha subunits in the nematode Caenorhabditis elegans. Cell Regulation. 2: 135-54. PMID 1907494 DOI: 10.1091/Mbc.2.2.135  0.356
1991 Amatruda TT, Steele DA, Slepak VZ, Simon MI. Gα16, a G protein α subunit specifically expressed in hematopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 88: 5587-5591. PMID 1905813 DOI: 10.1073/Pnas.88.13.5587  0.403
1991 Strathmann MP, Simon MI. G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits. Proceedings of the National Academy of Sciences of the United States of America. 88: 5582-6. PMID 1905812 DOI: 10.1073/Pnas.88.13.5582  0.328
1991 Simon MI, Strathmann MP, Gautam N. Diversity of G proteins in signal transduction. Science (New York, N.Y.). 252: 802-8. PMID 1902986 DOI: 10.1126/Science.1902986  0.601
1991 Bourret RB, Borkovich KA, Simon MI. Signal transduction pathways involving protein phosphorylation in prokaryotes Annual Review of Biochemistry. 60: 401-441. PMID 1883200 DOI: 10.1146/Annurev.Bi.60.070191.002153  0.336
1991 Lem J, Applebury ML, Falk JD, Flannery JG, Simon MI. Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice. Neuron. 6: 201-10. PMID 1825171 DOI: 10.1016/0896-6273(91)90356-5  0.305
1991 Pakula AA, Simon MI. Random cysteine disulfide crosslinking in the analysis of protein structure Methods. 3: 175-181. DOI: 10.1016/S1046-2023(05)80170-7  0.368
1990 Bourret RB, Hess JF, Simon MI. Conserved aspartate residues and phosphorylation in signal transduction by the chemotaxis protein CheY. Proceedings of the National Academy of Sciences of the United States of America. 87: 41-5. PMID 2404281 DOI: 10.1073/Pnas.87.1.41  0.378
1990 Borkovich KA, Simon MI. The dynamics of protein phosphorylation in bacterial chemotaxis Cell. 63: 1339-1348. PMID 2261645 DOI: 10.1016/0092-8674(90)90429-I  0.337
1990 Gautam N, Northup J, Tamir H, Simon MI. G protein diversity is increased by associations with a variety of gamma subunits. Proceedings of the National Academy of Sciences of the United States of America. 87: 7973-7. PMID 2122451 DOI: 10.1073/Pnas.87.20.7973  0.567
1990 Strathmann M, Wilkie TM, Simon MI. Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go. Proceedings of the National Academy of Sciences of the United States of America. 87: 6477-81. PMID 1697681 DOI: 10.1073/Pnas.87.17.6477  0.301
1989 Robinson MO, McCarrey JR, Simon MI. Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 86: 8437-8441. PMID 2813402 DOI: 10.1073/Pnas.86.21.8437  0.318
1989 Borkovich KA, Kaplan N, Hess JF, Simon MI. Transmembrane signal transduction in bacterial chemotaxis involves ligand-dependent activation of phosphate group transfer Proceedings of the National Academy of Sciences of the United States of America. 86: 1208-1212. PMID 2645576 DOI: 10.1073/Pnas.86.4.1208  0.382
1989 Simon MI, Borkovich KA, Bourret RB, Hess JF. Protein phosphorylation in the bacterial chemotaxis system Biochimie. 71: 1013-1019. PMID 2512992 DOI: 10.1016/0300-9084(89)90105-3  0.388
1989 Strathmann M, Wilkie TM, Simon MI. Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 86: 7407-9. PMID 2508088 DOI: 10.1073/Pnas.86.19.7407  0.379
1989 Gautam N, Baetscher M, Aebersold R, Simon MI. A G protein gamma subunit shares homology with ras proteins. Science (New York, N.Y.). 244: 971-4. PMID 2499046 DOI: 10.1126/Science.2499046  0.577
1988 Oosawa K, Mutoh N, Simon MI. Cloning of the C-terminal cytoplasmic fragment of the tar protein and effects of the fragment on chemotaxis of Escherichia coli. Journal of Bacteriology. 170: 2521-6. PMID 3286610 DOI: 10.1128/Jb.170.6.2521-2526.1988  0.364
1988 Hess JF, Oosawa K, Kaplan N, Simon MI. Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis. Cell. 53: 79-87. PMID 3280143 DOI: 10.1016/0092-8674(88)90489-8  0.395
1988 Hess JF, Bourret RB, Simon MI. Histidine phosphorylation and phosphoryl group transfer in bacterial chemotaxis. Nature. 336: 139-43. PMID 3185734 DOI: 10.1038/336139A0  0.378
1988 Hopkins RS, Stamnes MA, Simon MI, Hurley JB. Cholera toxin and pertussis toxin substrates and endogenous ADP-ribosyltransferase activity in Drosophila melanogaster. Biochimica Et Biophysica Acta. 970: 355-62. PMID 3135838 DOI: 10.1016/0167-4889(88)90135-8  0.562
1988 Amatruda TT, Gautam N, Fong HK, Northup JK, Simon MI. The 35- and 36-kDa beta subunits of GTP-binding regulatory proteins are products of separate genes. The Journal of Biological Chemistry. 263: 5008-11. PMID 3128533  0.465
1988 Hess JF, Bourret RB, Oosawa K, Matsumura P, Simon MI. Protein phosphorylation and bacterial chemotaxis. Cold Spring Harbor Symposia On Quantitative Biology. 53: 41-8. PMID 3076085 DOI: 10.1101/Sqb.1988.053.01.008  0.644
1988 Kaplan N, Simon MI. Purification and characterization of the wild-type and mutant carboxy-terminal domains of the Escherichia coli Tar chemoreceptor. Journal of Bacteriology. 170: 5134-40. PMID 3053644 DOI: 10.1128/Jb.170.11.5134-5140.1988  0.368
1988 Oosawa K, Hess JF, Simon MI. Mutants defective in bacterial chemotaxis show modified protein phosphorylation. Cell. 53: 89-96. PMID 2832069 DOI: 10.1016/0092-8674(88)90490-4  0.376
1988 Iino T, Komeda Y, Kutsukake K, Macnab RM, Matsumura P, Parkinson JS, Simon MI, Yamaguchi S. New unified nomenclature for the flagellar genes of Escherichia coli and Salmonella typhimurium. Microbiological Reviews. 52: 533-535. DOI: 10.1128/mmbr.52.4.533-535.1988  0.581
1987 Hess JF, Oosawa K, Matsumura P, Simon MI. Protein phosphorylation is involved in bacterial chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 84: 7609-13. PMID 3313398 DOI: 10.1073/Pnas.84.21.7609  0.668
1987 Bruist MF, Glasgow AC, Johnson RC, Simon MI. Fis binding to the recombinational enhancer of the Hin DNA inversion system. Genes & Development. 1: 762-72. PMID 2828170 DOI: 10.1101/Gad.1.8.762  0.317
1987 Johnson RC, Glasgow AC, Simon MI. Spatial relationship of the Fis binding sites for Hin recombinational enhancer activity. Nature. 329: 462-5. PMID 2821402 DOI: 10.1038/329462A0  0.311
1987 Johnson RC, Simon MI. Enhancers of site-specific recombination in bacteria Trends in Genetics. 3: 262-267. DOI: 10.1016/0168-9525(87)90261-7  0.318
1986 Johnson RC, Bruist MF, Simon MI. Host protein requirements for in vitro site-specific DNA inversion. Cell. 46: 531-9. PMID 3524854 DOI: 10.1016/0092-8674(86)90878-0  0.332
1986 Sparkes RS, Simon M, Cohn VH, Fournier RE, Lem J, Klisak I, Heinzmann C, Blatt C, Lucero M, Mohandas T. Assignment of the human and mouse prion protein genes to homologous chromosomes. Proceedings of the National Academy of Sciences of the United States of America. 83: 7358-62. PMID 3094007 DOI: 10.1073/Pnas.83.19.7358  0.322
1986 Fong HKW, Hurley JB, Hopkins RS, Miake-Lye R, Johnson MS, Doolittle RF, Simon MI. Repetitive segmental structure of the transducin β subunit: Homology with the CDC4 gene and identification of related mRNAs Proceedings of the National Academy of Sciences of the United States of America. 83: 2162-2166. PMID 3083416 DOI: 10.1073/Pnas.83.7.2162  0.516
1985 Plasterk RHA, Simon MI, Barbour AG. Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii Nature. 318: 257-263. PMID 4069202 DOI: 10.1038/318257A0  0.338
1985 Krikos A, Conley MP, Boyd A, Berg HC, Simon MI. Chimeric chemosensory transducers of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 82: 1326-30. PMID 3883356 DOI: 10.1073/Pnas.82.5.1326  0.365
1985 Lochrie MA, Hurley JB, Simon MI. Sequence of the alpha subunit of photoreceptor G protein: homologies between transducin, ras, and elongation factors. Science (New York, N.Y.). 228: 96-9. PMID 3856323 DOI: 10.1126/Science.3856323  0.559
1985 Johnson RC, Simon MI. Hin-mediated site-specific recombination requires two 26 bp recombination sites and a 60 bp recombinational enhancer. Cell. 41: 781-91. PMID 2988787 DOI: 10.1016/S0092-8674(85)80059-3  0.327
1985 Engebrecht J, Simon M, Silverman M. Measuring gene expression with light Science. 227: 1345-1347. PMID 2983423 DOI: 10.1126/Science.2983423  0.516
1985 Simon MI, Krikos A, Mutoh N, Boyd A. Chapter 1 Sensory Transduction in Bacteria Current Topics in Membranes and Transport. 23: 3-16. DOI: 10.1016/S0070-2161(08)60147-1  0.37
1984 Hurley JB, Fong HK, Teplow DB, Dreyer WJ, Simon MI. Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin. Proceedings of the National Academy of Sciences of the United States of America. 81: 6948-52. PMID 6438626 DOI: 10.1073/Pnas.81.22.6948  0.492
1984 Hurley JB, Simon MI, Teplow DB, Robishaw JD, Gilman AG. Homologies between signal transducing G proteins and ras gene products. Science (New York, N.Y.). 226: 860-2. PMID 6436980 DOI: 10.1126/Science.6436980  0.591
1984 Caccia N, Kronenberg M, Saxe D, Haars R, Bruns GAP, Goverman J, Malissen M, Willard H, Yoshikai Y, Simon M, Hood L, Mak TW. The T cell receptor β chain genes are located on chromosome 6 in mice and chromosome 7 in humans Cell. 37: 1091-1099. PMID 6331676 DOI: 10.1016/0092-8674(84)90443-4  0.31
1982 Boyd A, Mandel G, Simon MI. Integral membrane proteins required for bacterial motility and chemotaxis. Symposia of the Society For Experimental Biology. 35: 123-37. PMID 6764039  0.528
1980 Silverman M, Simon M. Phase variation: Genetic analysis of switching mutants Cell. 19: 845-854. PMID 6247071 DOI: 10.1016/0092-8674(80)90075-6  0.511
1978 Komeda Y, Silverman M, Matsumura P, Simon M. Genes for the hook-basal body proteins of the flagellar apparatus in Escherichia coli. Journal of Bacteriology. 134: 655-67. PMID 350831 DOI: 10.1128/Jb.134.2.655-667.1978  0.705
1978 Komeda Y, Silverman M, Simon M. Identification of the structural gene for the hook subunit protein of Escherichia coli flagella Journal of Bacteriology. 133: 364-371. PMID 338588  0.551
1977 Silverman M, Simon MI. Bacterial flagella Annual Review of Microbiology. 31: 397-419. PMID 410356  0.449
1977 Matsumura P, Silverman M, Simon M. Synthesis of mot and che gene products of Escherichia coli programmed by hybrid ColE1 plasmids in minicells. Journal of Bacteriology. 132: 996-1002. PMID 336614 DOI: 10.1128/Jb.132.3.996-1002.1977  0.691
1977 Ridgway HF, Silverman M, Simon MI. Localization of proteins controlling motility and chemotaxis in Escherichia coli Journal of Bacteriology. 132: 657-665. PMID 334749  0.527
1977 Komeda Y, Silverman M, Simon M. Genetic analysis of Escherichia coli K-12 region I flagellar mutants Journal of Bacteriology. 131: 801-808. PMID 330498  0.505
1977 Silverman M, Simon M. Identification of polypeptides necessary for chemotaxis in Escherichia coli Journal of Bacteriology. 130: 1317-1325. PMID 324984  0.533
1976 Silverman M, Matsumura P, Simon M. The identification of the mot gene product with Escherichia coli-lambda hybrids. Proceedings of the National Academy of Sciences of the United States of America. 73: 3126-30. PMID 787985 DOI: 10.1073/Pnas.73.9.3126  0.707
1974 Silverman M, Simon M. Assembly of hybrid flagellar filaments Journal of Bacteriology. 118: 750-752. PMID 4828311 DOI: 10.1128/Jb.118.2.750-752.1974  0.468
1974 Silverman M, Simon M. Positioning flagellar genes in Escherichia coli by deletion analysis Journal of Bacteriology. 117: 73-79. PMID 4587615 DOI: 10.1128/Jb.117.1.73-79.1974  0.519
1974 Silverman M, Simon M. Characterization of Escherichia coli flagellar mutants that are insensitive to catabolite repression Journal of Bacteriology. 120: 1196-1203. PMID 4373438 DOI: 10.1128/Jb.120.3.1196-1203.1974  0.514
1973 Silverman M, Simon M. Genetic analysis of bacteriophage Mu induced flagellar mutants in Escherichia coli Journal of Bacteriology. 116: 114-122. PMID 4583202 DOI: 10.1128/Jb.116.1.114-122.1973  0.508
1973 Silverman M, Simon M. Genetic analysis of flagellar mutants in Escherichia coli Journal of Bacteriology. 113: 105-113. PMID 4567134  0.483
1972 Silverman MR, Simon MI. Flagellar assembly mutants in Escherichia coli. Journal of Bacteriology. 112: 986-93. PMID 4117584 DOI: 10.1128/Jb.112.2.986-993.1972  0.498
1962 SIMON MI, VAN VUNAKIS H. The photodynamic reaction of methylene blue with deoxyribonucleic acid. Journal of Molecular Biology. 4: 488-99. PMID 13913131  0.478
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