| Year |
Citation |
Score |
| 2022 |
Chen BY, Salas JR, Trias AO, Perez Rodriguez A, Tsang JE, Guemes M, Le TM, Galic Z, Shepard HM, Steinman L, Nathanson DA, Czernin J, Witte ON, Radu CG, Schultz KA, et al. Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis. Immunology. PMID 35986643 DOI: 10.1111/imm.13569 |
0.448 |
|
| 2022 |
Le TM, Lee HR, Abt ER, Rashid K, Creech AL, Liang K, Cui J, Cho A, Wei L, Labora A, Chan C, Sanchez E, Kriti K, Karin D, Li L, ... ... Radu CG, et al. F-FDG PET visualizes systemic STING agonist-induced lymphocyte activation in preclinical models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35738905 DOI: 10.2967/jnumed.122.264121 |
0.576 |
|
| 2022 |
Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, Kim W, Wu N, Cui J, Cho A, Lee HR, ... ... Radu CG, et al. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Reports. 38: 110236. PMID 35021095 DOI: 10.1016/j.celrep.2021.110236 |
0.474 |
|
| 2021 |
Liang K, Abt ER, Le TM, Cho A, Dann AM, Cui J, Li L, Rashid K, Creech AL, Wei L, Ghukasyan R, Rosser EW, Wu N, Carlucci G, Czernin J, ... ... Radu CG, et al. STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [F]FLT PET imaging. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34480004 DOI: 10.1073/pnas.2105390118 |
0.589 |
|
| 2021 |
Czernin J, Radu C, Ribas A. Leadership Focus on Advancing Cancer Research and Treatment: A Conversation Between Johannes Czernin, Caius Radu, and Antoni Ribas. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 62: 1178-1180. PMID 34475241 DOI: 10.2967/jnumed.121.262937 |
0.389 |
|
| 2020 |
Sun DL, Poddar S, Pan RD, Rosser EW, Abt ER, Van Valkenburgh J, Le TM, Lok V, Hernandez SP, Song J, Li J, Turlik A, Chen X, Cheng CA, Chen W, ... ... Radu CG, et al. Isoquinoline thiosemicarbazone displays potent anticancer activity with efficacy against aggressive leukemias. Rsc Medicinal Chemistry. 11: 392-410. PMID 33479645 DOI: 10.1039/c9md00594c |
0.464 |
|
| 2020 |
Czernin J, Radu C. The Solutions Come from Science and Knowledge. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 33310739 DOI: 10.2967/jnumed.120.261792 |
0.31 |
|
| 2020 |
Stuparu AD, Capri JR, Meyer C, Le TM, Evans-Axelsson SL, Current K, Lennox M, Mona CE, Fendler WP, Calais J, Eiber M, Dahlbom M, Czernin J, Radu CG, Lückerath K, et al. Mechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 33277393 DOI: 10.2967/jnumed.120.256263 |
0.474 |
|
| 2020 |
Czernin J, Current K, Mona CE, Nyiranshuti L, Hikmat F, Radu CG, Lueckerath K. Immune-Checkpoint Blockade Enhances Ac-PSMA617 Efficacy in a Mouse Model of Prostate Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32646877 DOI: 10.2967/Jnumed.120.246041 |
0.485 |
|
| 2020 |
Bicak M, Lückerath K, Kalidindi T, Phelps ME, Strand SE, Morris MJ, Radu CG, Damoiseaux R, Peltola MT, Peekhaus N, Ho A, Veach D, Malmborg Hager AC, Larson SM, Lilja H, et al. Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32532924 DOI: 10.1073/Pnas.1918744117 |
0.349 |
|
| 2020 |
Stuparu AD, Meyer CAL, Evans-Axelsson SL, Lückerath K, Wei LH, Kim W, Poddar S, Mona CE, Dahlbom M, Girgis MD, Radu CG, Czernin J, Slavik R. Targeted alpha therapy in a systemic mouse model of prostate cancer - a feasibility study. Theranostics. 10: 2612-2620. PMID 32194823 DOI: 10.7150/Thno.42228 |
0.51 |
|
| 2020 |
Current K, Meyer C, Magyar CE, Mona CE, Almajano J, Slavik R, Stuparu AD, Cheng C, Dawson DW, Radu CG, Czernin J, Lueckerath K. Investigating PSMA-targeted radioligand therapy efficacy as a function of cellular PSMA levels and intra-tumoral PSMA heterogeneity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31932492 DOI: 10.1158/1078-0432.Ccr-19-1485 |
0.524 |
|
| 2020 |
Kim SS, Xu S, Cui J, Poddar S, Le TM, Hayrapetyan H, Li L, Wu N, Moore AM, Zhou L, Yu AC, Dann AM, Elliott IA, Abt ER, Kim W, ... ... Radu CG, et al. Histone deacetylase inhibition is synthetically lethal with arginine deprivation in pancreatic cancers with low argininosuccinate synthetase 1 expression. Theranostics. 10: 829-840. PMID 31903153 DOI: 10.7150/Thno.40195 |
0.358 |
|
| 2020 |
Le TM, Udyavar A, Kim W, Cho AE, Li L, DiRenzo D, Rosen B, Walters MJ, Tan JBL, Radu CG. Abstract A46: CD73 inhibition enhances the effect of anti-PD-1 therapy on KRAS-mutated pancreatic cancer model Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm19-A46 |
0.329 |
|
| 2019 |
Poddar S, Capparelli EV, Rosser EW, Gipson RM, Wei L, Le T, Jung ME, Radu C, Nikanjam M. Development and preclinical pharmacology of a novel dCK inhibitor, DI-87. Biochemical Pharmacology. 113742. PMID 31812677 DOI: 10.1016/J.Bcp.2019.113742 |
0.347 |
|
| 2019 |
Abt ER, Rosser EW, Durst MA, Lok V, Poddar S, Le TM, Cho A, Kim W, Wei L, Song J, Capri JR, Xu S, Wu N, Slavik R, Jung ME, ... ... Radu CG, et al. Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chemical Biology. PMID 31734178 DOI: 10.1016/J.Chembiol.2019.10.012 |
0.519 |
|
| 2019 |
Chen BY, Ghezzi C, Villegas B, Quon A, Radu CG, Witte ON, Clark PM. F-FAC PET visualizes brain-infiltrating leukocytes in a mouse model of multiple sclerosis. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31653711 DOI: 10.2967/Jnumed.119.229351 |
0.396 |
|
| 2019 |
Zhu Y, Smith DJ, Zhou Y, Li YR, Yu J, Lee D, Wang YC, Di Biase S, Wang X, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, ... ... Radu CG, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. PMID 31495780 DOI: 10.1016/J.Stem.2019.08.004 |
0.385 |
|
| 2019 |
Elliott IA, Dann AM, Xu S, Kim SS, Abt ER, Kim W, Poddar S, Moore A, Zhou L, Williams JL, Capri JR, Ghukasyan R, Matsumura C, Tucker DA, Armstrong WR, ... ... Radu CG, et al. Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894490 DOI: 10.1073/Pnas.1812410116 |
0.357 |
|
| 2019 |
Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Jolly J, Graham N, Christofk HR, Lowry WE. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nature Communications. 10: 91. PMID 30626875 DOI: 10.1038/S41467-018-07857-9 |
0.431 |
|
| 2019 |
Aguilera KY, Riahi R, Saadat EA, Lay AR, Le T, Donahue TR, Radu C, Dawson DW. Abstract C01: Porcupine inhibition redirects mitochondrial metabolism in Wnt-dependent pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C01 |
0.367 |
|
| 2019 |
Xu S, Elliott IA, Dann AM, Kim SS, Abe ER, Kim W, Poddar S, Moore A, Zhou L, Williams JL, Capri JR, Ghukasyan R, Matsumura C, Tucker DA, Armstrong WR, ... ... Radu CG, et al. Abstract 4264: Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion Cancer Research. 79: 4264-4264. DOI: 10.1158/1538-7445.Am2019-4264 |
0.368 |
|
| 2019 |
Capri J, Le T, Radu C, Donahue T. Abstract 4228: Integrated drug high-throughput screening and quantitative phosphoproteomics rationalizes combination therapy for mutant KRAS pancreatic cancer Cancer Research. 79: 4228-4228. DOI: 10.1158/1538-7445.Am2019-4228 |
0.335 |
|
| 2019 |
Meyer C, Stuparu A, Wei L, Capri J, Le T, Radu C, Czernin J, Dahlbom M, Slavik R. Therapeutic Efficacy and Dosimetry of Targeted Alpha Therapy using 225Ac-PSMA-617 in a Murine Model of Prostate Cancer Journal of Medical Imaging and Radiation Sciences. 50: S24. DOI: 10.1016/J.Jmir.2019.03.075 |
0.485 |
|
| 2018 |
Lückerath K, Wei L, Fendler WP, Evans-Axelsson S, Stuparu AD, Slavik R, Mona CE, Calais J, Rettig M, Reiter RE, Herrmann K, Radu CG, Czernin J, Eiber M. Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer. Ejnmmi Research. 8: 96. PMID 30374743 DOI: 10.1186/S13550-018-0451-Z |
0.503 |
|
| 2018 |
Garrett M, Sperry J, Braas D, Yan W, Le TM, Mottahedeh J, Ludwig K, Eskin A, Qin Y, Levy R, Breunig JJ, Pajonk F, Graeber TG, Radu CG, Christofk H, et al. Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities. Cancer & Metabolism. 6: 4. PMID 29692895 DOI: 10.1186/S40170-018-0177-4 |
0.324 |
|
| 2018 |
Lückerath K, Stuparu AD, Wei L, Kim W, Radu CG, Mona CE, Calais J, Rettig M, Reiter RE, Czernin J, Slavik R, Herrmann K, Eiber M, Fendler W. Detection threshold and reproducibility ofGa-PSMA11 PET/CT in a mouse model of prostate cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29602819 DOI: 10.2967/Jnumed.118.207704 |
0.576 |
|
| 2018 |
Abt ER, Dann A, Le TM, Capri JR, Cheng CM, Yi J, Poddar S, Kim W, Donahue TR, Radu CG. Abstract 4971: Identification of new modulators of nucleotide metabolism and replication stress in PDAC Cancer Research. 78: 4971-4971. DOI: 10.1158/1538-7445.Am2018-4971 |
0.376 |
|
| 2017 |
Antonios JP, Soto H, Everson RG, Moughon DL, Wang AC, Orpilla J, Radu C, Ellingson BM, Lee JT, Cloughesy T, Phelps ME, Czernin J, Liau LM, Prins RM. Detection of immune responses after immunotherapy in glioblastoma using PET and MRI. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874539 DOI: 10.1073/Pnas.1706689114 |
0.685 |
|
| 2017 |
Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, ... ... Radu CG, et al. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nature Communications. 8: 241. PMID 28808226 DOI: 10.1038/S41467-017-00221-3 |
0.546 |
|
| 2017 |
Fendler WP, Stuparu AD, Evans-Axelsson S, Lückerath K, Wei L, Kim W, Poddar S, Said J, Radu CG, Eiber M, Czernin J, Slavik R, Herrmann K. Establishing (177)Lu-PSMA-617 radioligand therapy in a syngeneic model of murine prostate cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28546332 DOI: 10.2967/Jnumed.117.193359 |
0.489 |
|
| 2017 |
Radu CG. Abstract IA20: PET imaging of the immune system using new nucleoside analog probes Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Ia20 |
0.516 |
|
| 2017 |
Nikanjam M, Poddar S, Capparelli E, Le T, Wei L, Radu C. Abstract 4064: Relating tumor drug concentrations to target effect with semi-physiologic PK-PD modeling in drug development: an application using a novel dCK inhibitor Cancer Research. 77: 4064-4064. DOI: 10.1158/1538-7445.Am2017-4064 |
0.334 |
|
| 2017 |
Soto H, Antonios J, Everson R, Moughon D, Wang A, Orpilla J, Radu C, Ellingson B, Lee J, Cloughesy T, Phelps M, Czernin J, Liau L, Prins R. NIMG-36. DELINEATION OF IMMUNE RESPONSES AFTER IMMUNOTHERAPY IN GLIOBLASTOMA USING PET AND MRI Neuro-Oncology. 19: vi149-vi150. DOI: 10.1093/Neuonc/Nox168.611 |
0.535 |
|
| 2016 |
Nguyen AH, Elliott IA, Wu N, Matsumura C, Vogelauer M, Attar N, Dann A, Ghukasyan R, Toste PA, Patel SG, Williams JL, Li L, Dawson DW, Radu C, Kurdistani SK, et al. Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts. Oncotarget. PMID 27894105 DOI: 10.18632/Oncotarget.13572 |
0.351 |
|
| 2016 |
Knezevic CE, Wright G, Remsing Rix LL, Kim W, Kuenzi BM, Luo Y, Watters JM, Koomen JM, Haura EB, Monteiro AN, Radu C, Lawrence HR, Rix U. Proteome-wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets. Cell Chemical Biology. PMID 27866910 DOI: 10.1016/J.Chembiol.2016.10.011 |
0.325 |
|
| 2016 |
Barrio M, Spick C, Radu CG, Lassmann M, Eberlein U, Allen-Auerbach MS, Schiepers C, Slavik R, Czernin J, Herrmann K. Human biodistribution and radiation dosimetry of 18F-CFA, a PET probe targeting the deoxyribonucleoside salvage pathway. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27811125 DOI: 10.2967/Jnumed.116.182394 |
0.577 |
|
| 2016 |
Laks DR, Ta L, Crisman TJ, Gao F, Coppola G, Radu CG, Nathanson DA, Kornblum HI. Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma. Molecular Cancer Therapeutics. PMID 27196770 DOI: 10.1158/1535-7163.Mct-15-0982 |
0.349 |
|
| 2016 |
Kim W, Le TM, Wei L, Poddar S, Bazzy J, Wang X, Uong NT, Abt ER, Capri JR, Austin WR, Van Valkenburgh JS, Steele D, Gipson RM, Slavik R, Cabebe AE, ... ... Radu CG, et al. [18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035974 DOI: 10.1073/Pnas.1524212113 |
0.678 |
|
| 2015 |
Kollareddy M, Dimitrova E, Vallabhaneni KC, Chan A, Le T, Chauhan KM, Carrero ZI, Ramakrishnan G, Watabe K, Haupt Y, Haupt S, Pochampally R, Boss GR, Romero DG, Radu CG, et al. Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities. Nature Communications. 6: 7389. PMID 26067754 DOI: 10.1038/Ncomms8389 |
0.371 |
|
| 2015 |
McCracken MN, Radu CG. Targeted noninvasive imaging of the innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 112: 5868-9. PMID 25934920 DOI: 10.1073/Pnas.1505899112 |
0.444 |
|
| 2014 |
Nomme J, Li Z, Gipson RM, Wang J, Armijo AL, Le T, Poddar S, Smith T, Santarsiero BD, Nguyen HA, Czernin J, Alexandrova AN, Jung ME, Radu CG, Lavie A. Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. Journal of Medicinal Chemistry. 57: 9480-94. PMID 25341194 DOI: 10.1021/Jm501124J |
0.505 |
|
| 2014 |
Bunimovich YL, Nair-Gill E, Riedinger M, McCracken MN, Cheng D, McLaughlin J, Radu CG, Witte ON. Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance. Plos One. 9: e104125. PMID 25101980 DOI: 10.1371/Journal.Pone.0104125 |
0.372 |
|
| 2014 |
Danilova N, Bibikova E, Covey TM, Nathanson D, Dimitrova E, Konto Y, Lindgren A, Glader B, Radu CG, Sakamoto KM, Lin S. The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia. Disease Models & Mechanisms. 7: 895-905. PMID 24812435 DOI: 10.1242/Dmm.015495 |
0.314 |
|
| 2014 |
Mosessian S, Duarte-Vogel SM, Stout DB, Roos KP, Lawson GW, Jordan MC, Ogden A, Matter C, Sadeghi S, Mills GQ, Schelbert HR, Radu CG, Czernin J, Couto M, Phelps ME. INDs for PET molecular imaging probes-approach by an academic institution. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 441-8. PMID 24733693 DOI: 10.1007/S11307-014-0735-2 |
0.555 |
|
| 2014 |
Chodon T, Comin-Anduix B, Chmielowski B, Koya RC, Wu Z, Auerbach M, Ng C, Avramis E, Seja E, Villanueva A, McCannel TA, Ishiyama A, Czernin J, Radu CG, Wang X, et al. Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2457-65. PMID 24634374 DOI: 10.1158/1078-0432.Ccr-13-3017 |
0.507 |
|
| 2014 |
Nathanson DA, Armijo AL, Tom M, Li Z, Dimitrova E, Austin WR, Nomme J, Campbell DO, Ta L, Le TM, Lee JT, Darvish R, Gordin A, Wei L, Liao HI, ... ... Radu CG, et al. Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. The Journal of Experimental Medicine. 211: 473-86. PMID 24567448 DOI: 10.1084/Jem.20131738 |
0.664 |
|
| 2014 |
Nomme J, Murphy JM, Su Y, Sansone ND, Armijo AL, Olson ST, Radu C, Lavie A. Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules. Acta Crystallographica. Section D, Biological Crystallography. 70: 68-78. PMID 24419380 DOI: 10.1107/S1399004713025030 |
0.31 |
|
| 2014 |
Radu CG, Nathanson DA, Czernin J. Abstract 5097: Co-targeting of convergent, switchable nucleotide biosynthetic pathways induces synthetic lethality in leukemia Cancer Research. 74: 5097-5097. DOI: 10.1158/1538-7445.Am2014-5097 |
0.56 |
|
| 2013 |
Escuin-Ordinas H, Elliott MW, Atefi M, Lee M, Ng C, Wei L, Comin-Anduix B, Montecino-Rodriguez E, Avramis E, Radu C, Sharp LL, Ribas A. PET imaging to non-invasively study immune activation leading to antitumor responses with a 4-1BB agonistic antibody. Journal For Immunotherapy of Cancer. 1: 14. PMID 24829750 DOI: 10.1186/2051-1426-1-14 |
0.42 |
|
| 2013 |
Wang J, Hwang K, Braas D, Dooraghi A, Nathanson D, Campbell DO, Gu Y, Sandberg T, Mischel P, Radu C, Chatziioannou AF, Phelps ME, Christofk H, Heath JR. Fast metabolic response to drug intervention through analysis on a miniaturized, highly integrated molecular imaging system. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1820-4. PMID 23978446 DOI: 10.2967/Jnumed.112.118497 |
0.386 |
|
| 2013 |
Murphy JM, Armijo AL, Nomme J, Lee CH, Smith QA, Li Z, Campbell DO, Liao HI, Nathanson DA, Austin WR, Lee JT, Darvish R, Wei L, Wang J, Su Y, ... ... Radu CG, et al. Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. Journal of Medicinal Chemistry. 56: 6696-708. PMID 23947754 DOI: 10.1021/Jm400457Y |
0.679 |
|
| 2013 |
Amaraesekera B, Marchis PD, Bobinski KP, Radu CG, Czernin J, Barrio JR, Michael van Dam R. High-pressure, compact, modular radiosynthesizer for production of positron emitting biomarkers. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 78: 88-101. PMID 23702794 DOI: 10.1016/J.Apradiso.2013.04.024 |
0.48 |
|
| 2013 |
Herrmann K, Dahlbom M, Nathanson D, Wei L, Radu C, Chatziioannou A, Czernin J. Evaluation of the Genisys4, a bench-top preclinical PET scanner. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1162-7. PMID 23628700 DOI: 10.2967/Jnumed.112.114926 |
0.55 |
|
| 2013 |
Gil JS, Machado HB, Campbell DO, McCracken M, Radu C, Witte ON, Herschman HR. Application of a rapid, simple, and accurate adenovirus-based method to compare PET reporter gene/PET reporter probe systems. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 273-81. PMID 23054556 DOI: 10.1007/S11307-012-0596-5 |
0.426 |
|
| 2013 |
Aarntzen EH, Srinivas M, Radu CG, Punt CJ, Boerman OC, Figdor CG, Oyen WJ, de Vries IJ. In vivo imaging of therapy-induced anti-cancer immune responses in humans. Cellular and Molecular Life Sciences : Cmls. 70: 2237-57. PMID 23052208 DOI: 10.1007/S00018-012-1159-2 |
0.353 |
|
| 2013 |
Danilova N, Elena B, Covey T, Nathanson D, Dimitrova E, Anne L, Glader B, Radu C, Sakamoto K, Lin S. Defective Nucleotide Metabolism Contributes To p53 Activation In Diamond-Blackfan Anemia Blood. 122: 1225-1225. DOI: 10.1182/Blood.V122.21.1225.1225 |
0.338 |
|
| 2012 |
Vatakis DN, Bristol GC, Kim SG, Levin B, Liu W, Radu CG, Kitchen SG, Zack JA. Using the BLT humanized mouse as a stem cell based gene therapy tumor model. Journal of Visualized Experiments : Jove. e4181. PMID 23271478 DOI: 10.3791/4181 |
0.354 |
|
| 2012 |
Austin WR, Armijo AL, Campbell DO, Singh AS, Hsieh T, Nathanson D, Herschman HR, Phelps ME, Witte ON, Czernin J, Radu CG. Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress. The Journal of Experimental Medicine. 209: 2215-28. PMID 23148236 DOI: 10.1084/Jem.20121061 |
0.506 |
|
| 2012 |
Yaghoubi SS, Campbell DO, Radu CG, Czernin J. Positron emission tomography reporter genes and reporter probes: gene and cell therapy applications. Theranostics. 2: 374-91. PMID 22509201 DOI: 10.7150/Thno.3677 |
0.569 |
|
| 2012 |
Lee JT, Campbell DO, Satyamurthy N, Czernin J, Radu CG. Stratification of nucleoside analog chemotherapy using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 275-80. PMID 22302964 DOI: 10.2967/Jnumed.111.090407 |
0.64 |
|
| 2012 |
Campbell DO, Yaghoubi SS, Su Y, Lee JT, Auerbach MS, Herschman H, Satyamurthy N, Czernin J, Lavie A, Radu CG. Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe. The Journal of Biological Chemistry. 287: 446-54. PMID 22074768 DOI: 10.1074/Jbc.M111.314666 |
0.68 |
|
| 2012 |
Benz MR, Czernin J, Allen-Auerbach MS, Dry SM, Sutthiruangwong P, Spick C, Radu C, Weber WA, Tap WD, Eilber FC. 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography for response assessment in soft tissue sarcoma: a pilot study to correlate imaging findings with tissue thymidine kinase 1 and Ki-67 activity and histopathologic response. Cancer. 118: 3135-44. PMID 22020872 DOI: 10.1002/Cncr.26630 |
0.571 |
|
| 2011 |
Vatakis DN, Koya RC, Nixon CC, Wei L, Kim SG, Avancena P, Bristol G, Baltimore D, Kohn DB, Ribas A, Radu CG, Galic Z, Zack JA. Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 108: E1408-16. PMID 22123951 DOI: 10.1073/Pnas.1115050108 |
0.372 |
|
| 2011 |
Ma C, Fan R, Ahmad H, Shi Q, Comin-Anduix B, Chodon T, Koya RC, Liu CC, Kwong GA, Radu CG, Ribas A, Heath JR. A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nature Medicine. 17: 738-43. PMID 21602800 DOI: 10.1038/Nm.2375 |
0.369 |
|
| 2011 |
Zheng X, Yu CL, Sha W, Radu C, Huang SC, Feng D. Study of an image-derived SUV and a modified SUV using mouse FDG-PET. Nuclear Medicine and Biology. 38: 353-62. PMID 21492784 DOI: 10.1016/J.Nucmedbio.2010.10.002 |
0.385 |
|
| 2011 |
Ng QK, Su H, Armijo AL, Czernin J, Radu CG, Segura T. Clustered Arg-Gly-Asp peptides enhances tumor targeting of nonviral vectors. Chemmedchem. 6: 623-7. PMID 21442757 DOI: 10.1002/Cmdc.201000541 |
0.516 |
|
| 2011 |
Schwarzenberg J, Radu CG, Benz M, Fueger B, Tran AQ, Phelps ME, Witte ON, Satyamurthy N, Czernin J, Schiepers C. Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. European Journal of Nuclear Medicine and Molecular Imaging. 38: 711-21. PMID 21127859 DOI: 10.1007/S00259-010-1666-Z |
0.61 |
|
| 2011 |
Ribas A, Chodon T, Comin-Anduix B, Sondergaard J, Mok S, Ng C, Escuin-Ordinas H, Atefi M, Chmielowski B, Czernin J, Witte ON, Radu CG, Koya RC. Abstract SY03-04: Novel imaging approaches for immunotherapy and targeted therapy of melanoma in animal models and humans Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy03-04 |
0.649 |
|
| 2011 |
Radu C, Lee JT, Campbell DO, Czernin J. Abstract SY03-02: Tumor metabolic phenotyping and treatment stratification by positron emission tomography Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy03-02 |
0.613 |
|
| 2010 |
Koya RC, Mok S, Comin-Anduix B, Chodon T, Radu CG, Nishimura MI, Witte ON, Ribas A. Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses. Proceedings of the National Academy of Sciences of the United States of America. 107: 14286-91. PMID 20624956 DOI: 10.1073/Pnas.1008300107 |
0.402 |
|
| 2010 |
Shu CJ, Campbell DO, Lee JT, Tran AQ, Wengrod JC, Witte ON, Phelps ME, Satyamurthy N, Czernin J, Radu CG. Novel PET probes specific for deoxycytidine kinase. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1092-8. PMID 20554721 DOI: 10.2967/Jnumed.109.073361 |
0.664 |
|
| 2010 |
Rabinovich BA, Radu CG. Imaging adoptive cell transfer based cancer immunotherapy. Current Pharmaceutical Biotechnology. 11: 672-84. PMID 20497110 DOI: 10.2174/138920110792246528 |
0.359 |
|
| 2010 |
Nair-Gill E, Wiltzius SM, Wei XX, Cheng D, Riedinger M, Radu CG, Witte ON. PET probes for distinct metabolic pathways have different cell specificities during immune responses in mice. The Journal of Clinical Investigation. 120: 2005-15. PMID 20484820 DOI: 10.1172/Jci41250 |
0.473 |
|
| 2010 |
Ribas A, Benz MR, Allen-Auerbach MS, Radu C, Chmielowski B, Seja E, Williams JL, Gomez-Navarro J, McCarthy T, Czernin J. Imaging of CTLA4 blockade-induced cell replication with (18)F-FLT PET in patients with advanced melanoma treated with tremelimumab. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 340-6. PMID 20150263 DOI: 10.2967/Jnumed.109.070946 |
0.59 |
|
| 2010 |
Toy G, Austin WR, Liao HI, Cheng D, Singh A, Campbell DO, Ishikawa TO, Lehmann LW, Satyamurthy N, Phelps ME, Herschman HR, Czernin J, Witte ON, Radu CG. Requirement for deoxycytidine kinase in T and B lymphocyte development. Proceedings of the National Academy of Sciences of the United States of America. 107: 5551-6. PMID 20080663 DOI: 10.1073/Pnas.0913900107 |
0.537 |
|
| 2010 |
Brewer S, Nair-Gill E, Wei B, Chen L, Li X, Riedinger M, Campbell DO, Wiltzius S, Satyamurthy N, Phelps ME, Radu C, Witte ON, Braun J. Epithelial uptake of [18F]1-(2'-deoxy-2'-arabinofuranosyl) cytosine indicates intestinal inflammation in mice. Gastroenterology. 138: 1266-75. PMID 20080095 DOI: 10.1053/J.Gastro.2010.01.003 |
0.377 |
|
| 2010 |
Guo D, Cloughesy TF, Radu CG, Mischel PS. AMPK: A metabolic checkpoint that regulates the growth of EGFR activated glioblastomas. Cell Cycle (Georgetown, Tex.). 9: 211-2. PMID 20023392 DOI: 10.4161/Cc.9.2.10540 |
0.405 |
|
| 2010 |
Laing RE, Nair-Gill E, Witte ON, Radu CG. Visualizing cancer and immune cell function with metabolic positron emission tomography. Current Opinion in Genetics & Development. 20: 100-5. PMID 19931447 DOI: 10.1016/J.Gde.2009.10.008 |
0.769 |
|
| 2010 |
Nair-Gill E, Wiltzius SM, Wei XX, Cheng D, Riedinger M, Radu CG, Witte ON. PET probes for distinct metabolic pathways have different cell specificities during immune responses in mice (Molecular and Cellular Proteomics (2010) 120, 7, (2641)) Journal of Clinical Investigation. 120: 2641. DOI: 10.1172/JCI41250C1 |
0.309 |
|
| 2009 |
Guo D, Hildebrandt IJ, Prins RM, Soto H, Mazzotta MM, Dang J, Czernin J, Shyy JY, Watson AD, Phelps M, Radu CG, Cloughesy TF, Mischel PS. The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 12932-7. PMID 19625624 DOI: 10.1073/Pnas.0906606106 |
0.537 |
|
| 2009 |
Kwong GA, Radu CG, Hwang K, Shu CJ, Ma C, Koya RC, Comin-Anduix B, Hadrup SR, Bailey RC, Witte ON, Schumacher TN, Ribas A, Heath JR. Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells. Journal of the American Chemical Society. 131: 9695-703. PMID 19552409 DOI: 10.1021/Ja9006707 |
0.315 |
|
| 2009 |
Wang H, Wang S, Su H, Chen KJ, Armijo AL, Lin WY, Wang Y, Sun J, Kamei K, Czernin J, Radu CG, Tseng HR. A supramolecular approach for preparation of size-controlled nanoparticles. Angewandte Chemie (International Ed. in English). 48: 4344-8. PMID 19425037 DOI: 10.1002/anie.200900063 |
0.405 |
|
| 2009 |
Laing RE, Walter MA, Campbell DO, Herschman HR, Satyamurthy N, Phelps ME, Czernin J, Witte ON, Radu CG. Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 106: 2847-52. PMID 19196993 DOI: 10.1073/Pnas.0812890106 |
0.77 |
|
| 2009 |
Yu ZT, Kamei K, Takahashi H, Shu CJ, Wang X, He GW, Silverman R, Radu CG, Witte ON, Lee KB, Tseng HR. Integrated microfluidic devices for combinatorial cell-based assays. Biomedical Microdevices. 11: 547-55. PMID 19130244 DOI: 10.1007/S10544-008-9260-X |
0.319 |
|
| 2009 |
Shu CJ, Radu CG, Shelly SM, Vo DD, Prins R, Ribas A, Phelps ME, Witte ON. Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen. International Immunology. 21: 155-65. PMID 19106231 DOI: 10.1093/Intimm/Dxn133 |
0.45 |
|
| 2009 |
Farrell JJ, Tomlinson JS, Czernin J, Radu CG. S1284 Novel Molecular Immune System Imaging of Autoimmune Pancreatitis with L-FAC-PET Imaging: Comparison with FDG-PET Gastroenterology. 136: A-229. DOI: 10.1016/S0016-5085(09)61033-7 |
0.494 |
|
| 2008 |
Wei LH, Olafsen T, Radu C, Hildebrandt IJ, McCoy MR, Phelps ME, Meares C, Wu AM, Czernin J, Weber WA. Engineered antibody fragments with infinite affinity as reporter genes for PET imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 1828-35. PMID 18927335 DOI: 10.2967/Jnumed.108.054452 |
0.535 |
|
| 2008 |
Radu CG, Shu CJ, Nair-Gill E, Shelly SM, Barrio JR, Satyamurthy N, Phelps ME, Witte ON. Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog. Nature Medicine. 14: 783-8. PMID 18542051 DOI: 10.1038/Nm1724 |
0.455 |
|
| 2008 |
Tumeh PC, Radu CG, Ribas A. PET imaging of cancer immunotherapy. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 865-8. PMID 18511842 DOI: 10.2967/Jnumed.108.051342 |
0.498 |
|
| 2008 |
Nair-Gill ED, Shu CJ, Radu CG, Witte ON. Non-invasive imaging of adaptive immunity using positron emission tomography. Immunological Reviews. 221: 214-28. PMID 18275485 DOI: 10.1111/J.1600-065X.2008.00585.X |
0.4 |
|
| 2008 |
Prins RM, Shu CJ, Radu CG, Vo DD, Khan-Farooqi H, Soto H, Yang MY, Lin MS, Shelly S, Witte ON, Ribas A, Liau LM. Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain. Cancer Immunology, Immunotherapy : Cii. 57: 1279-89. PMID 18253732 DOI: 10.1007/S00262-008-0461-1 |
0.351 |
|
| 2007 |
McLaughlin J, Cheng D, Singer O, Lukacs RU, Radu CG, Verma IM, Witte ON. Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics. Proceedings of the National Academy of Sciences of the United States of America. 104: 20501-6. PMID 18079287 DOI: 10.1073/Pnas.0710532105 |
0.339 |
|
| 2007 |
Radu CG, Shu CJ, Shelly SM, Phelps ME, Witte ON. Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 104: 1937-42. PMID 17261805 DOI: 10.1073/Pnas.0610544104 |
0.443 |
|
| 2006 |
Radu CG, Cheng D, Nijagal A, Riedinger M, McLaughlin J, Yang LV, Johnson J, Witte ON. Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-cell death-associated gene 8 receptor. Molecular and Cellular Biology. 26: 668-77. PMID 16382156 DOI: 10.1128/Mcb.26.2.668-677.2006 |
0.336 |
|
| 2005 |
Shu CJ, Guo S, Kim YJ, Shelly SM, Nijagal A, Ray P, Gambhir SS, Radu CG, Witte ON. Visualization of a primary anti-tumor immune response by positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 102: 17412-7. PMID 16293690 DOI: 10.1073/Pnas.0508698102 |
0.479 |
|
| 2003 |
Deng C, Radu C, Diab A, Tsen MF, Hussain R, Cowdery JS, Racke MK, Thomas JA. IL-1 receptor-associated kinase 1 regulates susceptibility to organ-specific autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 170: 2833-42. PMID 12626533 DOI: 10.4049/Jimmunol.170.6.2833 |
0.315 |
|
| 2002 |
Deng C, Minguela A, Hussain RZ, Lovett-Racke AE, Radu C, Ward ES, Racke MK. Expression of the tyrosine phosphatase SRC homology 2 domain-containing protein tyrosine phosphatase 1 determines T cell activation threshold and severity of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 168: 4511-8. PMID 11970996 DOI: 10.4049/Jimmunol.168.9.4511 |
0.332 |
|
| 2001 |
Garcia KC, Radu CG, Ho J, Ober RJ, Sally Ward E. Kinetics and thermodynamics of T cell receptor-autoantigen interactions in murine experimental autoimmune encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. 98: 6818-6823. PMID 11391002 DOI: 10.1073/Pnas.111161198 |
0.305 |
|
| 2000 |
Radu CG, Anderton SM, Firan M, Wraith DC, Ward ES. Detection of autoreactive T cells in H-2(u) mice using peptide-MHC multimers International Immunology. 12: 1553-1560. PMID 11058575 DOI: 10.1093/Intimm/12.11.1553 |
0.312 |
|
| 1998 |
Borvak J, Richardson J, Medesan C, Antohe F, Radu C, Simionescu M, Ghetie V, Ward ES. Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice. International Immunology. 10: 1289-1298. PMID 9786428 DOI: 10.1093/Intimm/10.9.1289 |
0.332 |
|
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