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Michelle M. Le Beau - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Cancer cytogenetics and genetics
Website:
http://t-aml.uchicago.edu/scientific-leadership/michelle-le-beau/

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Stoddart A, Wang J, Fernald AA, Davis EM, Johnson CR, Hu C, Cheng JX, McNerney ME, Le Beau MM. Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms. Blood Cancer Discovery. 1. PMID 32924016 DOI: 10.1158/2643-3230.bcd-19-0028  0.342
2016 Meyer SE, Qin T, Muench DE, Masuda K, Venkatasubramanian M, Orr E, Suarez L, Gore SD, Delwel R, Paietta E, Tallman MS, Fernandez H, Melnick A, Le Beau MM, Kogan S, et al. Dnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia. Cancer Discovery. PMID 27016502 DOI: 10.1158/2159-8290.Cd-16-0008  0.39
2016 Stoddart A, Qian Z, Fernald AA, Bergerson RJ, Wang J, Karrison T, Anastasi J, Bartom ET, Sarver AL, McNerney ME, Largaespada DA, Le Beau MM. Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms. Haematologica. PMID 26944478 DOI: 10.3324/Haematol.2015.139527  0.338
2015 Sundaravel S, Duggan R, Bhagat T, Ebenezer DL, Liu H, Yu Y, Bartenstein M, Unnikrishnan M, Karmakar S, Liu TC, Torregroza I, Quenon T, Anastasi J, McGraw KL, Pellagatti A, ... ... Le Beau MM, et al. Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. Proceedings of the National Academy of Sciences of the United States of America. 112: E6359-E6368. PMID 26578796 DOI: 10.1073/Pnas.1516394112  0.33
2015 Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG. Dissecting the role of aberrant DNA methylation in human leukaemia. Nature Communications. 6: 7091. PMID 25997600 DOI: 10.1038/Ncomms8091  0.36
2014 Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 512: 198-202. PMID 25079315 DOI: 10.1038/Nature13619  0.344
2014 Young DJ, Stoddart A, Nakitandwe J, Chen SC, Qian Z, Downing JR, Le Beau MM. Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts. Haematologica. 99: 1032-40. PMID 24532040 DOI: 10.3324/haematol.2013.098657  0.315
2014 Stoddart A, Fernald AA, Wang J, Davis EM, Karrison T, Anastasi J, Le Beau MM. Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice. Blood. 123: 1069-78. PMID 24381225 DOI: 10.1182/blood-2013-07-517953  0.391
2014 Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, et al. β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6. PMID 24371308 DOI: 10.1073/Pnas.1315752111  0.348
2014 Stoddart A, Wang J, Fernald AA, Karrison T, Anastasi J, Le Beau MM. Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc. Blood. 123: 228-38. PMID 24264229 DOI: 10.1182/blood-2013-05-506568  0.344
2013 Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis. Blood. 121: 2059-63. PMID 23315164 DOI: 10.1182/Blood-2012-04-421065  0.309
2013 McNerney ME, Brown CD, Wang X, Bartom ET, Karmakar S, Bandlamudi C, Yu S, Ko J, Sandall BP, Stricker T, Anastasi J, Grossman RL, Cunningham JM, Le Beau MM, White KP. CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia. Blood. 121: 975-83. PMID 23212519 DOI: 10.1182/Blood-2012-04-426965  0.434
2011 Godley LA, Cunningham J, Dolan ME, Huang RS, Gurbuxani S, McNerney ME, Larson RA, Leong H, Lussier Y, Onel K, Odenike O, Stock W, White KP, Le Beau MM. An integrated genomic approach to the assessment and treatment of acute myeloid leukemia. Seminars in Oncology. 38: 215-24. PMID 21421111 DOI: 10.1053/J.Seminoncol.2011.01.003  0.333
2011 Lubelsky Y, Sasaki T, Kuipers MA, Lucas I, Le Beau MM, Carignon S, Debatisse M, Prinz JA, Dennis JH, Gilbert DM. Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone. Nucleic Acids Research. 39: 3141-55. PMID 21148149 DOI: 10.1093/Nar/Gkq1276  0.342
2010 Jones L, Wei G, Sevcikova S, Phan V, Jain S, Shieh A, Wong JC, Li M, Dubansky J, Maunakea ML, Ochoa R, Zhu G, Tennant TR, Shannon KM, Lowe SW, ... Le Beau MM, et al. Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia. The Journal of Experimental Medicine. 207: 2581-94. PMID 21059853 DOI: 10.1084/Jem.20091071  0.388
2010 Mohrin M, Bourke E, Alexander D, Warr MR, Barry-Holson K, Le Beau MM, Morrison CG, Passegué E. Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. Cell Stem Cell. 7: 174-85. PMID 20619762 DOI: 10.1016/J.Stem.2010.06.014  0.304
2010 Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Research. 70: 5840-50. PMID 20587527 DOI: 10.1158/0008-5472.CAN-10-0847  0.305
2010 Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K. Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies. Blood. 115: 4524-32. PMID 20233966 DOI: 10.1182/Blood-2009-07-232504  0.367
2010 Wang J, Fernald AA, Anastasi J, Le Beau MM, Qian Z. Haploinsufficiency of Apc leads to ineffective hematopoiesis. Blood. 115: 3481-8. PMID 20065296 DOI: 10.1182/blood-2009-11-251835  0.365
2010 Qian Z, Joslin JM, Tennant TR, Reshmi SC, Young DJ, Stoddart A, Larson RA, Le Beau MM. Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia. Chemico-Biological Interactions. 184: 50-7. PMID 19958752 DOI: 10.1016/J.Cbi.2009.11.025  0.744
2010 Palakodeti A, Lucas I, Jiang Y, Young DJ, Fernald AA, Karrison T, Le Beau MM. Impaired replication dynamics at the FRA3B common fragile site. Human Molecular Genetics. 19: 99-110. PMID 19815620 DOI: 10.1093/Hmg/Ddp470  0.699
2009 Jiang Y, Lucas I, Young DJ, Davis EM, Karrison T, Rest JS, Le Beau MM. Common fragile sites are characterized by histone hypoacetylation. Human Molecular Genetics. 18: 4501-12. PMID 19717471 DOI: 10.1093/Hmg/Ddp410  0.6
2008 Wong JC, Le Beau MM, Shannon K. Tumor suppressor gene inactivation in myeloid malignancies. Best Practice & Research. Clinical Haematology. 21: 601-14. PMID 19041599 DOI: 10.1016/J.Beha.2008.09.001  0.378
2008 Mullighan CG, Miller CB, Radtke I, Phillips LA, Dalton J, Ma J, White D, Hughes TP, Le Beau MM, Pui CH, Relling MV, Shurtleff SA, Downing JR. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature. 453: 110-4. PMID 18408710 DOI: 10.1038/nature06866  0.347
2008 Kirsammer G, Jilani S, Liu H, Davis E, Gurbuxani S, Le Beau MM, Crispino JD. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. 111: 767-75. PMID 17901249 DOI: 10.1182/Blood-2007-04-085670  0.324
2007 Lucas I, Palakodeti A, Jiang Y, Young DJ, Jiang N, Fernald AA, Le Beau MM. High-throughput mapping of origins of replication in human cells. Embo Reports. 8: 770-7. PMID 17668008 DOI: 10.1038/Sj.Embor.7401026  0.71
2007 Joslin JM, Fernald AA, Tennant TR, Davis EM, Kogan SC, Anastasi J, Crispino JD, Le Beau MM. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood. 110: 719-26. PMID 17420284 DOI: 10.1182/Blood-2007-01-068809  0.756
2007 Boyapati A, Yan M, Peterson LF, Biggs JR, Le Beau MM, Zhang DE. A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy. Blood. 109: 3963-71. PMID 17197431 DOI: 10.1182/blood-2006-09-045583  0.365
2007 Lones MA, Heerema NA, Le Beau MM, Sposto R, Perkins SL, Kadin ME, Kjeldsberg CR, Meadows A, Siegel S, Buckley J, Abromowitch M, Kersey J, Bergeron S, Cairo MS, Sanger WG. Chromosome abnormalities in advanced stage lymphoblastic lymphoma of children and adolescents: a report from CCG-E08 Cancer Genetics and Cytogenetics. 172: 1-11. PMID 17175373 DOI: 10.1016/J.Cancergencyto.2006.07.011  0.349
2006 Lones MA, Heerema NA, Le Beau MM, Perkins SL, Kadin ME, Kjeldsberg CR, Sposto R, Meadows A, Siegel S, Buckley J, Finlay J, Abromowitch M, Cairo MS, Sanger WG. Complex secondary chromosome abnormalities in advanced stage anaplastic large cell lymphoma of children and adolescents: a report from CCG-E08. Cancer Genetics and Cytogenetics. 171: 89-96. PMID 17116485 DOI: 10.1016/J.Cancergencyto.2006.04.019  0.362
2006 Stephens K, Weaver M, Leppig KA, Maruyama K, Emanuel PD, Le Beau MM, Shannon KM. Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies. Blood. 108: 1684-9. PMID 16690971 DOI: 10.1182/Blood-2005-11-011486  0.4
2006 Djokic M, Le Beau MM, Swinnen LJ, Smith SM, Rubin CM, Anastasi J, Carlson KM. Post-transplant lymphoproliferative disorder subtypes correlate with different recurring chromosomal abnormalities. Genes, Chromosomes & Cancer. 45: 313-8. PMID 16283619 DOI: 10.1002/gcc.20287  0.314
2005 Larson RA, Le Beau MM. Therapy-related myeloid leukaemia: a model for leukemogenesis in humans. Chemico-Biological Interactions. 153: 187-95. PMID 15935816 DOI: 10.1016/j.cbi.2005.03.023  0.344
2005 Curtiss NP, Bonifas JM, Lauchle JO, Balkman JD, Kratz CP, Emerling BM, Green ED, Le Beau MM, Shannon KM. Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22. Genomics. 85: 600-7. PMID 15820312 DOI: 10.1016/J.Ygeno.2005.01.013  0.399
2005 Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D, Kogan SC, Radhakrishnan A, Le Beau MM, Largman C, Lawrence HJ. HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. Blood. 105: 1456-66. PMID 15522959 DOI: 10.1182/blood-2004-04-1583  0.369
2004 Lones MA, Sanger WG, Le Beau MM, Heerema NA, Sposto R, Perkins SL, Buckley J, Kadin ME, Kjeldsberg CR, Meadows A, Siegel S, Finlay J, Bergeron S, Cairo MS. Chromosome abnormalities may correlate with prognosis in Burkitt/Burkitt-like lymphomas of children and adolescents: a report from Children's Cancer Group Study CCG-E08. Journal of Pediatric Hematology/Oncology. 26: 169-78. PMID 15125609 DOI: 10.1097/00043426-200403000-00006  0.348
2004 Palakodeti A, Han Y, Jiang Y, Le Beau MM. The role of late/slow replication of the FRA16D in common fragile site induction. Genes, Chromosomes & Cancer. 39: 71-6. PMID 14603443 DOI: 10.1002/Gcc.10290  0.695
2003 Le Beau MM, Davis EM, Patel B, Phan VT, Sohal J, Kogan SC. Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia. Blood. 102: 1072-4. PMID 12689927 DOI: 10.1182/Blood-2003-01-0155  0.303
2003 Lensch MW, Tischkowitz M, Christianson TA, Reifsteck CA, Speckhart SA, Jakobs PM, O'Dwyer ME, Olson SB, Le Beau MM, Hodgson SV, Mathew CG, Larson RA, Bagby GC. Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia. Blood. 102: 7-16. PMID 12637330 DOI: 10.1182/blood-2002-09-2781  0.352
2002 Emerling BM, Bonifas J, Kratz CP, Donovan S, Taylor BR, Green ED, Le Beau MM, Shannon KM. MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia. Oncogene. 21: 4849-54. PMID 12101424 DOI: 10.1038/Sj.Onc.1205615  0.376
2002 Le Beau MM, Bitts S, Davis EM, Kogan SC. Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia. Blood. 99: 2985-91. PMID 11929790 DOI: 10.1182/blood.V99.8.2985  0.366
2002 Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia. Proceedings of the National Academy of Sciences of the United States of America. 99: 3070-5. PMID 11867721 DOI: 10.1073/pnas.042702899  0.45
2002 Kratz CP, Emerling BM, Bonifas J, Wang W, Green ED, Le Beau MM, Shannon KM. Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor. Blood. 99: 372-4. PMID 11756194 DOI: 10.1182/Blood.V99.1.372  0.448
2001 Kratz CP, Emerling BM, Donovan S, Laig-Webster M, Taylor BR, Thompson P, Jensen S, Banerjee A, Bonifas J, Makalowski W, Green ED, Le Beau MM, Shannon KM. Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies. Genomics. 77: 171-80. PMID 11597142 DOI: 10.1006/Geno.2001.6636  0.457
2001 Lai F, Godley LA, Joslin J, Fernald AA, Liu J, Espinosa R, Zhao N, Pamintuan L, Till BG, Larson RA, Qian Z, Le Beau MM. Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q). Genomics. 71: 235-45. PMID 11161817 DOI: 10.1006/Geno.2000.6414  0.752
2001 Stoffel A, Le Beau MM. The API2/MALT1 fusion product may lead to germinal center B cell lymphomas by suppression of apoptosis. Human Heredity. 51: 1-7. PMID 11096264 DOI: 10.1159/000022952  0.366
2001 Gozzetti A, Le Beau MM. Fluorescence in situ hybridization: uses and limitations. Seminars in Hematology. 37: 320-33. PMID 11071355 DOI: 10.1016/S0037-1963(00)90013-1  0.321
2001 Wang PW, Eisenbart JD, Espinosa R, Davis EM, Larson RA, Le Beau MM. Refinement of the smallest commonly deleted segment of chromosome 20 in malignant myeloid diseases and development of a PAC-based physical and transcription map. Genomics. 67: 28-39. PMID 10945467 DOI: 10.1006/geno.2000.6215  0.463
2000 Lai F, Godley LA, Fernald AA, Orelli BJ, Pamintuan L, Zhao N, Le Beau MM. cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins. Genomics. 70: 123-30. PMID 11087669 DOI: 10.1006/Geno.2000.6345  0.382
2000 Lai F, Orelli BJ, Till BG, Godley LA, Fernald AA, Pamintuan L, Le Beau MM. Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene. Genomics. 66: 65-75. PMID 10843806 DOI: 10.1006/Geno.2000.6181  0.411
2000 Shuster MI, Han L, Le Beau MM, Davis E, Sawicki M, Lese CM, Park NH, Colicelli J, Gollin SM. A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification. Genes, Chromosomes & Cancer. 28: 153-63. PMID 10825000 DOI: 10.1002/(Sici)1098-2264(200006)28:2<153::Aid-Gcc4>3.0.Co;2-9  0.441
2000 Lai F, Fernald AA, Zhao N, Le Beau MM. cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene. Gene. 248: 117-25. PMID 10806357 DOI: 10.1016/S0378-1119(00)00135-9  0.387
1999 Godley LA, Lai F, Liu J, Zhao N, Le Beau MM. TTID: A novel gene at 5q31 encoding a protein with titin-like features. Genomics. 60: 226-33. PMID 10486214 DOI: 10.1006/Geno.1999.5912  0.342
1999 Wang PW, Eisenbart JD, Cordes SP, Barsh GS, Stoffel M, Le Beau MM. Human KRML (MAFB): cDNA cloning, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. Genomics. 59: 275-81. PMID 10444328 DOI: 10.1006/Geno.1999.5884  0.444
1999 Stoffel A, Rao PH, Louie DC, Krauter K, Liebowitz DN, Koeppen H, Le Beau MM, Chaganti RSK. Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC Genes Chromosomes and Cancer. 24: 156-159. PMID 9885983 DOI: 10.1002/(Sici)1098-2264(199902)24:2<156::Aid-Gcc9>3.0.Co;2-X  0.415
1998 Zhao N, Lai F, Fernald AA, Eisenbart JD, Espinosa R, Wang PW, Le Beau MM. Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias. Genomics. 53: 184-90. PMID 9790767 DOI: 10.1006/geno.1998.5473  0.428
1998 Chen M, She H, Davis EM, Spicer CM, Kim L, Ren R, Le Beau MM, Li W. Identification of Nck family genes, chromosomal localization, expression, and signaling specificity. The Journal of Biological Chemistry. 273: 25171-8. PMID 9737977 DOI: 10.1074/Jbc.273.39.25171  0.31
1998 Dissing M, Le Beau MM, Pedersen-Bjergaard J. Inversion of chromosome 16 and uncommon rearrangements of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia: rare events related to DNA-topoisomerase II inhibitors? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 16: 1890-6. PMID 9586906 DOI: 10.1200/jco.1998.16.5.1890  0.364
1998 Le Beau MM, Drabkin H, Glover TW, Gemmill R, Rassool FV, McKeithan TW, Smith DI. An FHIT tumor suppressor gene? Genes, Chromosomes & Cancer. 21: 281-9. PMID 9559339 DOI: 10.1002/(SICI)1098-2264(199804)21:4<281::AID-GCC1>3.0.CO;2-V  0.301
1998 Le Beau MM, Rassool FV, Neilly ME, Espinosa R, Glover TW, Smith DI, McKeithan TW. Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction. Human Molecular Genetics. 7: 755-61. PMID 9499431 DOI: 10.1093/hmg/7.4.755  0.483
1998 Wang PW, Iannantuoni K, Davis EM, Espinosa R, Stoffel M, Le Beau MM. Refinement of the commonly deleted segment in myeloid leukemias with a del(20q). Genes, Chromosomes & Cancer. 21: 75-81. PMID 9491317 DOI: 10.1002/(Sici)1098-2264(199802)21:2<75::Aid-Gcc1>3.0.Co;2-4  0.423
1998 Wang P, Spielberger RT, Thangavelu M, Zhao N, Davis EM, Iannantuoni K, Larson RA, Le Beau MM. dic(5;17): a recurring abnormality in malignant myeloid disorders associated with mutations of TP53. Genes, Chromosomes & Cancer. 20: 282-91. PMID 9365836 DOI: 10.1002/(SICI)1098-2264(199711)20:3<282::AID-GCC9>3.0.CO;2-Z  0.302
1998 Roulston D, Espinosa R, Nucifora G, Larson RA, Le Beau MM, Rowley JD. CBFA2(AML1) Translocations With Novel Partner Chromosomes in Myeloid Leukemias: Association With Prior Therapy Blood. 92: 2879-2885. DOI: 10.1182/blood.v92.8.2879  0.451
1997 Ong ST, Fong KM, Bader SA, Minna JD, Le Beau MM, McKeithan TW, Rassool FV. Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines. Genes, Chromosomes & Cancer. 20: 16-23. PMID 9290949 DOI: 10.1002/(SICI)1098-2264(199709)20:1<16::AID-GCC3>3.0.CO;2-C  0.387
1997 Sato Y, Bohlander SK, Kobayashi H, Suto Y, Davis EM, Espinosa R, Le Beau MM, Rowley JD. Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in situ hybridization in a patient with acute myeloid leukemia (AML-M6). Cancer Genetics and Cytogenetics. 97: 157-60. PMID 9283600 DOI: 10.1016/S0165-4608(96)00335-4  0.321
1997 Zhao N, Stoffel A, Wang PW, Eisenbart JD, Espinosa R, Larson RA, Le Beau MM. Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map. Proceedings of the National Academy of Sciences of the United States of America. 94: 6948-53. PMID 9192672 DOI: 10.1073/pnas.94.13.6948  0.442
1997 Levi-Setti R, Chabala JM, Gavrilov K, Espinosa R, Le Beau MM. Imaging of BrdU-labeled human metaphase chromosomes with a high resolution scanning ion microprobe. Microscopy Research and Technique. 36: 301-12. PMID 9140930 DOI: 10.1002/(Sici)1097-0029(19970215)36:4<301::Aid-Jemt8>3.0.Co;2-O  0.372
1997 Janßen U, Davis EM, Le Beau MM, Stoffel W. Human mitochondrial enoyl-CoA hydratase gene (ECHS1): Structural organization and assignment to chromosome 10q26.2-q26.3 Genomics. 40: 470-475. PMID 9073515 DOI: 10.1006/Geno.1996.4597  0.423
1997 Broccoli D, Chong L, Oelmann S, Fernald AA, Marziliano N, van Steensel B, Kipling D, Le Beau MM, de Lange T. Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains. Human Molecular Genetics. 6: 69-76. PMID 9002672 DOI: 10.1093/Hmg/6.1.69  0.336
1996 Furuta H, Nishi S, Le Beau MM, Fernald AA, Yano H, Bell GI. Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. Genomics. 36: 206-9. PMID 8812439 DOI: 10.1006/Geno.1996.0448  0.317
1996 Rassool FV, Le Beau MM, Shen ML, Neilly ME, Espinosa R, Ong ST, Boldog F, Drabkin H, McCarroll R, McKeithan TW. Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2 Genomics. 35: 109-117. PMID 8661111 DOI: 10.1006/geno.1996.0329  0.412
1996 Bosio A, Binczek E, Le Beau MM, Fernald AA, Stoffel W. The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. Genomics. 34: 69-75. PMID 8661025 DOI: 10.1006/Geno.1996.0242  0.367
1996 Stoffel M, Le Beau MM, Espinosa R, Bohlander SF, Le Paslier D, Cohen D, Xiang KS, Cox NJ, Fajans SS, Bell GI. A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene. Proceedings of the National Academy of Sciences of the United States of America. 93: 3937-41. PMID 8632993 DOI: 10.1073/Pnas.93.9.3937  0.451
1996 Takeda J, Espinosa R, Eng S, Le Beau MM, Bell GI. Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library. Genomics. 29: 276-81. PMID 8530086 DOI: 10.1006/Geno.1995.1245  0.33
1995 Stoffel M, Espinosa R, Trabb JB, Le Beau MM, Bell GI. Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7. Genomics. 23: 697-9. PMID 7851900 DOI: 10.1006/Geno.1994.1560  0.435
1995 Le Beau MM, Song C, Davis EM, Hiipakka RA, Kokontis JM, Liao S. Assignment of the human ubiquitous receptor gene (UNR) to 19q13.3 using fluorescence in situ hybridization. Genomics. 26: 166-8. PMID 7782080 DOI: 10.1016/0888-7543(95)80100-Z  0.382
1995 Dreyling MH, Kobayashi H, Olopade OI, Le Beau MM, Rowley JD, Bohlander SK. Detection of 9p deletions in leukemia cell lines by interphase fluorescence in situ hybridization with YAC-derived probes. Cancer Genetics and Cytogenetics. 83: 46-55. PMID 7656204 DOI: 10.1016/S0165-4608(95)00026-7  0.32
1995 Rassool FV, Neilly ME, McGuire KL, McKeithan TW, Le Beau MM. Localization of the chinese hamster MHC locus to chromosome 1q17→q18 by fluorescence in situ hybridization Cytogenetic and Genome Research. 71: 62-63. PMID 7606930 DOI: 10.1159/000134064  0.4
1995 Olopade OI, Pomykala HM, Hagos F, Sveen LW, Espinosa R, Dreyling MH, Gursky S, Stadler WM, Le Beau MM, Bohlander SK. Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21. Proceedings of the National Academy of Sciences of the United States of America. 92: 6489-93. PMID 7604019 DOI: 10.1073/Pnas.92.14.6489  0.384
1995 Martinez-Climent JA, Espinosa R, Thirman MJ, Le Beau MM, Rowley JD. Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival. Journal of Pediatric Hematology/Oncology. 17: 277-83. PMID 7583381 DOI: 10.1097/00043426-199511000-00001  0.332
1995 el-Maghrabi MR, Lange AJ, Jiang W, Yamagata K, Stoffel M, Takeda J, Fernald AA, Le Beau MM, Bell GI, Baker L. Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. Genomics. 27: 520-5. PMID 7558035 DOI: 10.1006/Geno.1995.1085  0.333
1995 Dreyling M, Bohlander S, Le Beau M, Olopade O. Refined mapping of genomic rearrangements involving the short arm of chromosome 9 in acute lymphoblastic leukemias and other hematologic malignancies Blood. 86: 1931-1938. DOI: 10.1182/Blood.V86.5.1931.Bloodjournal8651931  0.392
1995 Sato Y, Suto Y, Pietenpol J, Golub T, Gilliland D, Davis E, Le Beau M, Roberts J, Vogelstein B, Rowley J. TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies Blood. 86: 1525-1533. DOI: 10.1182/Blood.V86.4.1525.Bloodjournal8641525  0.371
1994 Bohlander SK, Espinosa R, Fernald AA, Rowley JD, Le Beau MM, Díaz MO. Sequence-independent amplification and labeling of yeast artificial chromosomes for fluorescence in situ hybridization. Cytogenetics and Cell Genetics. 65: 108-10. PMID 8404060  0.325
1994 Yasuda K, Espinosa R, Takeda J, Le Beau MM, Bell GI. Localization of the kappa opioid receptor gene to human chromosome band 8q11.2. Genomics. 19: 596-7. PMID 8188308 DOI: 10.1006/Geno.1994.1117  0.421
1994 Le Beau MM, Carver LA, Espinosa R, Schmidt JV, Bradfield CA. Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15. Cytogenetics and Cell Genetics. 66: 172-6. PMID 8125016 DOI: 10.1159/000133694  0.359
1994 Stoffel M, Espinosa R, Powell KL, Philipson LH, Le Beau MM, Bell GI. Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): Localization to chromosome 2 and identification of a simple tandem repeat polymorphism Genomics. 21: 254-256. PMID 8088798 DOI: 10.1006/Geno.1994.1253  0.409
1994 Menzel S, Stoffel M, Espinosa R, Fernald AA, Le Beau MM, Bell GI. Localization of the glucagon receptor gene to human chromosome band 17q25. Genomics. 20: 327-8. PMID 8020989 DOI: 10.1006/Geno.1994.1179  0.449
1994 Jones EM, Menzel S, Espinosa R, Le Beau MM, Bell GI, Takeda J. Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism. Genomics. 23: 490-1. PMID 7835902 DOI: 10.1006/Geno.1994.1529  0.443
1994 German MS, Wang J, Fernald AA, Espinosa R, Le Beau MM, Bell GI. Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13. Genomics. 24: 403-4. PMID 7698771 DOI: 10.1006/geno.1994.1639  0.302
1994 Kobayashi H, Montgomery K, Bohlander S, Adra C, Lim B, Kucherlapati R, Donis-Keller H, Holt M, Le Beau M, Rowley J. Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases Blood. 84: 3473-3482. DOI: 10.1182/blood.v84.10.3473.3473  0.41
1993 Le Beau MM, Espinosa R, Neuman WL, Stock W, Roulston D, Larson RA, Keinanen M, Westbrook CA. Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. Proceedings of the National Academy of Sciences of the United States of America. 90: 5484-8. PMID 8516290 DOI: 10.1073/Pnas.90.12.5484  0.429
1993 Sturrock AB, Espinosa R, Hoidal JR, Le Beau MM. Localization of the gene encoding proteinase-3 (the Wegener's granulomatosis autoantigen) to human chromosome band 19p13.3. Cytogenetics and Cell Genetics. 64: 33-4. PMID 8508676 DOI: 10.1159/000133555  0.364
1993 Baron BW, Nucifora G, McCabe N, Espinosa R, Le Beau MM, McKeithan TW. Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 90: 5262-6. PMID 8506375 DOI: 10.1073/pnas.90.11.5262  0.468
1993 Stoffel M, Xiang KS, Espinosa R, Cox NJ, Le Beau MM, Bell GI. cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young. Human Molecular Genetics. 2: 1-4. PMID 8490617 DOI: 10.1093/Hmg/2.1.1  0.392
1993 Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI. Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms. Genomics. 15: 449-52. PMID 8449518 DOI: 10.1006/Geno.1993.1088  0.435
1993 Kobayashi H, Espinosa R, Thirman MJ, Gill HJ, Fernald AA, Diaz MO, Le Beau MM, Rowley JD. Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization. Blood. 82: 547-51. PMID 8329710  0.355
1993 Yasuda K, Espinosa R, Davis EM, Le Beau MM, Bell GI. Human somatostatin receptor genes: Localization of SSTR5 to human chromosome 20p11.2 Genomics. 17: 785-786. PMID 8244401 DOI: 10.1006/Geno.1993.1410  0.328
1993 Neuman WL, Westbrook CA, Dixon M, Espinosa R, Patel YD, Nakamura Y, Weiffenbach B, Le Beau MM. Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization. Cytogenetics and Cell Genetics. 62: 207-10. PMID 8095009 DOI: 10.1159/000133477  0.314
1993 Kobayashi H, Espinosa R, Thirman MJ, Fernald AA, Shannon K, Diaz MO, Le Beau MM, Rowley JD. Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 7: 204-8. PMID 7692945 DOI: 10.1002/Gcc.2870070404  0.365
1993 Sanford JP, Sait SNJ, Pan L, Nowak NJ, Gill HJ, Le Beau MM, Diaz MO, Zabel B, Shows TB. Characterization of two 11q23.3-11q24 deletions and mapping of associated anonymous DNA markers Genes Chromosomes and Cancer. 7: 67-73. PMID 7687455 DOI: 10.1002/gcc.2870070202  0.464
1993 Kobayashi H, Espinosa R, Fernald AA, Begy C, Diaz MO, Le Beau MM, Rowley JD. Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 8: 246-52. PMID 7512368 DOI: 10.1002/gcc.2870080407  0.412
1993 Super H, McCabe N, Thirman M, Larson R, Le Beau M, Pedersen-Bjergaard J, Philip P, Diaz M, Rowley J. Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA- topoisomerase II Blood. 82: 3705-3711. DOI: 10.1182/blood.v82.12.3705.3705  0.367
1993 Anastasi J, Feng J, Le Beau M, Larson R, Rowley J, Vardiman J. Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion Blood. 81: 1580-1585. DOI: 10.1182/blood.v81.6.1580.bloodjournal8161580  0.319
1992 Rubin CM, Le Beau MM, Mick R, Bitter MA, Nachman J, Rudinsky R, Appel HJ, Morgan E, Suarez CR, Schumacher HR. Impact of chromosomal translocations on prognosis in childhood acute lymphoblastic leukemia. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 9: 2183-92. PMID 1960559 DOI: 10.1200/JCO.1991.9.12.2183  0.325
1992 Xia Y, Brown L, Yang CY, Tsan JT, Siciliano MJ, Espinosa R, Le Beau MM, Baer RJ. TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 88: 11416-20. PMID 1763056 DOI: 10.1073/pnas.88.24.11416  0.365
1992 Espinosa R, Lemons RS, Perlman RK, Kuo WL, Rosner MR, Le Beau MM. Localization of the gene encoding insulin-degrading enzyme to human chromosome 10, bands q23----q25. Cytogenetics and Cell Genetics. 57: 184-6. PMID 1743072 DOI: 10.1159/000133142  0.395
1992 Thangavelu M, Neuman WL, Espinosa R, Nakamura Y, Westbrook CA, Le Beau MM. A physical and genetic linkage map of the distal long arm of human chromosome 5. Cytogenetics and Cell Genetics. 59: 27-30. PMID 1733669 DOI: 10.1159/000133193  0.371
1992 Davey FR, Lawrence D, MacCallum J, Varney J, Hutchison R, Wurster-Hill D, Schiffer C, Sobol RE, Ciminelli N, Le Beau M, Bloomfield CD. Morphologic characteristics of acute lymphoblastic leukemie (ALL) with abnormalities of chromosome 8, band q24 American Journal of Hematology. 40: 183-191. PMID 1609772 DOI: 10.1002/ajh.2830400306  0.303
1992 Brown L, Espinosa R, Le Beau MM, Siciliano MJ, Baer R. HEN1 and HEN2: a subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma. Proceedings of the National Academy of Sciences of the United States of America. 89: 8492-6. PMID 1528853 DOI: 10.1073/pnas.89.18.8492  0.323
1992 Levi-Setti R, Le Beau M. Cytogenetic applications of high resolution secondary ion imaging microanalysis: detection and mapping of tracer isotopes in human chromosomes. Biology of the Cell. 74: 51-8. PMID 1511248 DOI: 10.1016/0248-4900(92)90008-O  0.301
1992 Bohlander SK, Espinosa R, Le Beau MM, Rowley JD, Díaz MO. A method for the rapid sequence-independent amplification of microdissected chromosomal material. Genomics. 13: 1322-4. PMID 1505965 DOI: 10.1016/0888-7543(92)90057-Y  0.412
1992 Yeldandi AV, Patel YD, Liao M, Kao FT, Rao MS, Reddy JK, Le Beau MM. Localization of the human urate oxidase gene (UOX) to 1p22. Cytogenetics and Cell Genetics. 61: 121-2. PMID 1395718 DOI: 10.1159/000133386  0.327
1992 Neuman WL, Le Beau MM, Farber RA, Lindgren V, Westbrook CA. Somatic cell hybrid mapping of human chromosome band 5q31: a region important to hematopoiesis. Cytogenetics and Cell Genetics. 61: 103-6. PMID 1395713 DOI: 10.1159/000133381  0.426
1992 Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia Genomics. 14: 437-443. PMID 1385305 DOI: 10.1016/S0888-7543(05)80238-1  0.351
1992 Onodera N, McCabe NR, Nachman JB, Johnson FL, Le Beau MM, Rowley JD, Rubin CM. Hyperdiploidy arising from near-haploidy in childhood acute lymphoblastic leukemia. Genes, Chromosomes & Cancer. 4: 331-6. PMID 1377941 DOI: 10.1002/gcc.2870040410  0.413
1992 Park JK, Le Beau MM, Shows TB, Rowley JD, Diaz MO. A complex genetic rearrangement in a t(10;14)(q24;q11) associated with T- cell acute lymphoblastic leukemia Genes Chromosomes and Cancer. 4: 32-40. PMID 1377007  0.413
1992 Paietta E, Van Ness B, Le Beau MM, Bennett J, Cassileth P, Wiernik PH. Translocation (2;9)(p12;p23) in a case of acute leukemia with t(4;11)(q21;q23). Lack of rearrangement of the kappa and interferon gene loci. Cancer Genetics and Cytogenetics. 60: 82-5. PMID 1375531 DOI: 10.1016/0165-4608(92)90238-4  0.336
1992 Dixon MJ, Dixon J, Raskova D, Le Beau MM, Williamson R, Klinger K, Landes GM. Genetic and physical mapping of the Treacher Collins syndrome locus: refinement of the localization to chromosome 5q32-33.2. Human Molecular Genetics. 1: 249-53. PMID 1303194 DOI: 10.1093/hmg/1.4.249  0.376
1992 Larson R, Le Beau M, Ratain M, Rowley J. Balanced translocations involving chromosome bands 11q23 and 21q22 in therapy-related leukemia [letter] Blood. 79: 1892-1893. DOI: 10.1182/blood.v79.7.1892.1892  0.325
1992 Neuman W, Rubin C, Rios R, Larson R, Le Beau M, Rowley J, Vardiman J, Schwartz J, Farber R. Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders Blood. 79: 1501-1510. DOI: 10.1182/blood.v79.6.1501.1501  0.429
1991 Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K. Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein. The Journal of Cell Biology. 111: 2673-9. PMID 2277079 DOI: 10.1083/jcb.111.6.2673  0.389
1991 Le Beau MM, Geurts van Kessel AH. Report of the committee on the genetic constitution of chromosome 18. Cytogenetics and Cell Genetics. 55: 216-7. PMID 2073836 DOI: 10.1159/000133014  0.317
1991 Rubin CM, Le Beau MM. Cytogenetic abnormalities in childhood acute lymphoblastic leukemia. The American Journal of Pediatric Hematology/Oncology. 13: 202-16. PMID 2069231 DOI: 10.1097/00043426-199122000-00017  0.304
1991 Gao J, Erickson P, Gardiner K, Le Beau MM, Diaz MO, Patterson D, Rowley JD, Drabkin HA. Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia Proceedings of the National Academy of Sciences of the United States of America. 88: 4882-4886. PMID 2052570 DOI: 10.1073/Pnas.88.11.4882  0.487
1991 Mancuso DJ, Tuley EA, Westfield LA, Lester-Mancuso TL, Le Beau MM, Sorace JM, Sadler JE. Human von Willebrand factor gene and pseudogene: structural analysis and differentiation by polymerase chain reaction. Biochemistry. 30: 253-69. PMID 1988024 DOI: 10.1021/bi00215a036  0.312
1991 Westbrook CA, Neuman WL, Hewitt J, Kidd KK, Le Beau MM, Williamson R. Report of the chromosome 5 workshop. Genomics. 10: 1105-9. PMID 1916818 DOI: 10.1016/0888-7543(91)90211-V  0.345
1991 Lorenzana AN, Rubin CM, Le Beau MM, Nachman J, Connolly P, Subramanian U, Johnson FL, McKeithan TW. Immunoglobulin gene rearrangements in acute lymphoblastic leukemia with the 9;11 translocation. Genes, Chromosomes & Cancer. 3: 74-7. PMID 1906342 DOI: 10.1002/gcc.2870030113  0.333
1991 Rassool FV, McKeithan TW, Neilly ME, van Melle E, Espinosa R, Le Beau MM. Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites. Proceedings of the National Academy of Sciences of the United States of America. 88: 6657-61. PMID 1862089 DOI: 10.1073/pnas.88.15.6657  0.447
1991 Rosenberg M, Fuchs E, Le Beau MM, Eddy RL, Shows TB. Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12. Cytogenetics and Cell Genetics. 57: 33-8. PMID 1713141 DOI: 10.1159/000133109  0.392
1991 Burnett RC, David JC, Harden AM, Le Beau MM, Rowley JD, Diaz MO. The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2. Genes, Chromosomes & Cancer. 3: 461-7. PMID 1663780 DOI: 10.1002/gcc.2870030608  0.458
1991 Anastasi J, Vardiman J, Rudinsky R, Patel M, Nachman J, Rubin C, Le Beau M. Direct correlation of cytogenetic findings with cell morphology using in situ hybridization: an analysis of suspicious cells in bone marrow specimens of two patients completing therapy for acute lymphoblastic leukemia Blood. 77: 2456-2462. DOI: 10.1182/blood.v77.11.2456.2456  0.324
1990 Lemons RS, Espinosa R, Rebentisch M, McCormick F, Ladner M, Le Beau MM. Chromosomal localization of the gene encoding GTPase-activating protein (RASA) to human chromosome 5, bands q13-q15. Genomics. 6: 383-5. PMID 2307479 DOI: 10.1016/0888-7543(90)90581-E  0.381
1990 Chada S, Le Beau MM, Casey L, Newburger PE. Isolation and chromosomal localization of the human glutathione peroxidase gene Genomics. 6: 268-271. PMID 2307470 DOI: 10.1016/0888-7543(90)90566-D  0.423
1990 Chandrasekharappa SC, Rebelsky MS, Firak TA, Le Beau MM, Westbrook CA. A long-range restriction map of the interleukin-4 and interleukin-5 linkage group on chromosome 5. Genomics. 6: 94-9. PMID 2303264 DOI: 10.1016/0888-7543(90)90452-Z  0.395
1990 Diaz MO, Rubin CM, Harden A, Ziemin S, Larson RA, Le Beau MM, Rowley JD. Deletions of interferon genes in acute lymphoblastic leukemia. The New England Journal of Medicine. 322: 77-82. PMID 2294436 DOI: 10.1056/NEJM199001113220202  0.359
1990 Ohno H, Furukawa T, Fukuhara S, Zong SQ, Kamesaki H, Shows TB, Le Beau MM, McKeithan TW, Kawakami T, Honjo T. Molecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigen. Proceedings of the National Academy of Sciences of the United States of America. 87: 628-32. PMID 2153959 DOI: 10.1073/Pnas.87.2.628  0.436
1990 Becker MA, Heidler SA, Bell GI, Seino S, Le Beau MM, Westbrook CA, Neuman W, Shapiro LJ, Mohandas TK, Roessler BJ. Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes. Genomics. 8: 555-61. PMID 1962753 DOI: 10.1016/0888-7543(90)90043-T  0.434
1990 Watson ML, Kingsmore SF, Johnston GI, Siegelman MH, Le Beau MM, Lemons RS, Bora NS, Howard TA, Weissman IL, McEver RP. Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. The Journal of Experimental Medicine. 172: 263-72. PMID 1694218 DOI: 10.1084/jem.172.1.263  0.423
1990 Gulcher JR, Alexakos MJ, Le Beau MM, Lemons RS, Stefansson K. Chromosomal localization of the human hexabrachion (tenascin) gene and evidence for recent reduplication within the gene. Genomics. 6: 616-22. PMID 1692804 DOI: 10.1016/0888-7543(90)90495-G  0.394
1990 Rubin C, Larson R, Anastasi J, Winter J, Thangavelu M, Vardiman J, Rowley J, Le Beau M. t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy- related myelodysplastic syndrome and acute myeloid leukemia Blood. 76: 2594-2598. DOI: 10.1182/blood.v76.12.2594.2594  0.31
1989 Testa JR, Parsa NZ, Le Beau MM, Vande Woude GF. Localization of the proto-oncogene MOS to 8q11-q12 by in situ chromosomal hybridization. Genomics. 3: 44-7. PMID 3220476 DOI: 10.1016/0888-7543(88)90157-7  0.386
1989 Thangavelu M, Bitter MA, Larson RA, Davis EM, Rowley JD, Le Beau MM. Der(5)t(5;7)(q11.2;p11.2): a new recurring abnormality in malignant myeloid disorders. Cancer Genetics and Cytogenetics. 37: 1-8. PMID 2917326 DOI: 10.1016/0165-4608(89)90067-8  0.368
1989 Le Beau MM, Ryan D, Pericak-Vance MA. Report of the committee on the genetic constitution of chromosomes 18 and 19. Cytogenetics and Cell Genetics. 51: 338-57. PMID 2676376 DOI: 10.1159/000132798  0.317
1989 Rubin CM, Le Beau MM. Chromosomal abnormalities in myeloid hematologic malignancies. Current Topics in Microbiology and Immunology. 149: 25-34. PMID 2659280 DOI: 10.1007/978-3-642-74623-9_2  0.35
1989 Park JK, McKeithan TW, Le Beau MM, Bitter MA, Frankli n WA, Rowley JD, Diaz MO. An (8;14)(q24;q11) translocation involving the T-cell receptor α-chain gene and the MYC oncogene 3' region in a B-cell lymphoma Genes Chromosomes and Cancer. 1: 15-22. PMID 2535034  0.431
1989 Hooberman AL, Carrino JJ, Leibowitz D, Rowley JD, Le Beau MM, Arlin ZA, Westbrook CA. Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 86: 4259-63. PMID 2498881 DOI: 10.1073/Pnas.86.11.4259  0.346
1989 Thangavelu M, Le Beau MM. Chromosomal Abnormalities in Hodgkin’s Disease Hematology/Oncology Clinics of North America. 3: 221-236. DOI: 10.1016/S0889-8588(18)30552-5  0.309
1988 Harris BN, Davis EM, Le Beau MM, Bitter MA, Kaminer LS, Morgan E, Rowley JD. Variant translocations (9;11): identification of the critical genetic rearrangement. Cancer Genetics and Cytogenetics. 30: 171-5. PMID 3422044 DOI: 10.1016/0165-4608(88)90108-2  0.369
1988 Martin AO, Northrup H, Ledbetter DH, Trask B, van den Engh G, Le Beau MM, Beaudet AL, Gray JW, Sekhon G, Krassikoff N. Prenatal detection of 46,XY,rec(5),dup q, inv(5)(p13q33) using DNA analysis, flow cytometry, and in situ hybridization to supplement classical cytogenetic analysis. American Journal of Medical Genetics. 31: 643-54. PMID 3228143 DOI: 10.1002/Ajmg.1320310320  0.338
1988 Davidson MK, Le Beau MM, Eddy RL, Shows TB, DiPietro LA, Kingzette M, Hanly WC. Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31----q41. Cytogenetics and Cell Genetics. 48: 107-11. PMID 3197448 DOI: 10.1159/000132601  0.426
1988 Hattori K, Angel P, Le Beau MM, Karin M. Structure and chromosomal localization of the functional intronless human JUN protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 85: 9148-52. PMID 3194415 DOI: 10.1073/pnas.85.23.9148  0.366
1988 Anastasi J, Pettenati MJ, Le Beau MM, Kwaan HC, Weil SC. Acute lymphoblastic leukemia in a patient with longstanding polycythemia vera: Cytogenetic analysis reveals two distinct abnormal clones American Journal of Hematology. 29: 33-37. PMID 3177367 DOI: 10.1002/ajh.2830290108  0.317
1988 Joseph LJ, Le Beau MM, Jamieson GA, Acharya S, Shows TB, Rowley JD, Sukhatme VP. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure. Proceedings of the National Academy of Sciences of the United States of America. 85: 7164-8. PMID 3140236 DOI: 10.1073/pnas.85.19.7164  0.307
1988 Diaz MO, Ziemin S, Le Beau MM, Pitha P, Smith SD, Chilcote RR, Rowley JD. Homozygous deletion of the α- and β1-interferon genes in human leukemia and derived cell lines Proceedings of the National Academy of Sciences of the United States of America. 85: 5259-5263. PMID 3134658 DOI: 10.1073/pnas.85.14.5259  0.386
1988 Weil SC, Rosner GL, Reid MS, Chisholm RL, Lemons RS, Swanson MS, Carrino JJ, Diaz MO, Le Beau MM. Translocation and rearrangement of myeloperoxidase gene in acute promyelocytic leukemia. Science (New York, N.Y.). 240: 790-2. PMID 2896388 DOI: 10.1126/Science.2896388  0.456
1988 Farber RA, Phalen T, Neuman WL, Le Beau MM, Wasmuth JJ, Dobbs M. An anonymous DNA segment pTP5E (D5S70) maps to the long arm of chromosome 5 and identifies a Taq I polymorphism. Nucleic Acids Research. 16: 2360. PMID 2895914 DOI: 10.1093/Nar/16.5.2360  0.425
1988 Westbrook C, Rubin C, Carrino J, Le Beau M, Bernards A, Rowley J. Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis Blood. 71: 697-702. DOI: 10.1182/Blood.V71.3.697.697  0.454
1987 Le Beau MM, Epstein ND, O'Brien SJ, Nienhuis AW, Yang YC, Clark SC, Rowley JD. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q Proceedings of the National Academy of Sciences of the United States of America. 84: 5913-5917. PMID 3497400 DOI: 10.1073/Pnas.84.16.5913  0.409
1987 Pettenati MJ, Le Beau MM, Lemons RS, Shima EA, Kawasaki ES, Larson RA, Sherr CJ, Diaz MO, Rowley JD. Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders. Proceedings of the National Academy of Sciences of the United States of America. 84: 2970-4. PMID 3495006 DOI: 10.1073/pnas.84.9.2970  0.422
1987 Rubin CM, Larson RA, Bitter MA, Carrino JJ, Le Beau MM, Diaz MO, Rowley JD. Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia Blood. 70: 1338-1342. PMID 3478099  0.344
1987 Westbrook CA, Rubin CM, Le Beau MM, Kaminer LS, Smith SD, Rowley JD, Diaz MO. Molecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 84: 251-5. PMID 3025859 DOI: 10.1073/Pnas.84.1.251  0.411
1987 Lublin DM, Lemons RS, Le Beau MM, Holers VM, Tykocinski ML, Medof ME, Atkinson JP. The gene encoding decay-accelerating factor (DAF) is located in the complement-regulatory locus on the long arm of chromosome 1 Journal of Experimental Medicine. 165: 1731-1736. PMID 2438369 DOI: 10.1084/jem.165.6.1731  0.376
1987 Chilcote R, Le Beau M, Dampier C, Pergament E, Verlinsky Y, Mohandas N, Frischer H, Rowley J. Association of red cell spherocytosis with deletion of the short arm of chromosome 8 Blood. 69: 156-159. DOI: 10.1182/blood.V69.1.156.bloodjournal691156  0.408
1986 Le Beau MM, Albain KS, Larson RA, Vardiman JW, Davis EM, Blough RR, Golomb HM, Rowley JD. Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 4: 325-45. PMID 3950675 DOI: 10.1200/JCO.1986.4.3.325  0.38
1986 Le Beau MM, McKeithan TW, Shima EA, Goldman-Leikin RE, Chan SJ, Bell GI, Rowley JD, Diaz MO. T-cell receptor α-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11) Proceedings of the National Academy of Sciences of the United States of America. 83: 9744-9748. PMID 3540949 DOI: 10.1073/Pnas.83.24.9744  0.382
1986 McKeithan TW, Shima EA, Le Beau MM, Minowada J, Rowley JD, Diaz MO. Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor α-chain gene and sequences on the 3' side of MYC Proceedings of the National Academy of Sciences of the United States of America. 83: 6636-6640. PMID 3529089 DOI: 10.1073/pnas.83.17.6636  0.393
1986 Shima EA, Le Beau MM, McKeithan TW, Minowada J, Showe LC, Mak TW, Minden MD, Rowley JD, Diaz MO. Gene encoding the alpha chain of the T-cell receptor is moved immediately downstream of c-myc in a chromosomal 8;14 translocation in a cell line from a human T-cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 83: 3439-43. PMID 3517860 DOI: 10.1073/Pnas.83.10.3439  0.393
1986 Le Beau MM, Rowley JD. Chromosomal abnormalities in leukemia and lymphoma: clinical and biological significance. Advances in Human Genetics. 15: 1-54. PMID 3513482 DOI: 10.1007/978-1-4615-8356-1_1  0.316
1986 Le Beau MM, Pettenati MJ, Lemons RS, Diaz MO, Westbrook CA, Larson RA, Sherr CJ, Rowley JD. Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders. Cold Spring Harbor Symposia On Quantitative Biology. 51: 899-909. PMID 3495397 DOI: 10.1101/Sqb.1986.051.01.103  0.364
1986 Le Beau MM, Westbrook CA, Diaz MO, Larson RA, Rowley JD, Gasson JC, Golde DW, Sherr CJ. Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders. Science (New York, N.Y.). 231: 984-7. PMID 3484837 DOI: 10.1126/Science.3484837  0.415
1986 Le Beau MM, Rowley JD, Ferro MT, San Román C. Constitutional t(15;17): clarification of the chromosomal breakpoints. Cancer Genetics and Cytogenetics. 20: 175-7. PMID 3455857 DOI: 10.1016/0165-4608(86)90124-X  0.326
1986 Diaz MO, Le Beau MM, Pitha P, Rowley JD. Interferon and c-ets-1 genes in the translocation (9;11)(p22;q23) in human acute monoytic leukemia Science. 231: 265-267. PMID 3455787  0.443
1986 Le Beau MM, Rowley JD, Sacchi N, Watson DK, Papas TS, Diaz MO. Hu-ets-2 is translocated to chromosome 8 in the t(8;21) in acute myelogenous leukemia Cancer Genetics and Cytogenetics. 23: 269-274. PMID 3021321 DOI: 10.1016/0165-4608(86)90189-5  0.422
1986 Look AT, Peiper SC, Rebentisch MB, Ashmun RA, Roussel MF, Lemons RS, Le Beau MM, Rubin CM, Sherr CJ. Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150) Journal of Clinical Investigation. 78: 914-921. PMID 2428842 DOI: 10.1172/JCI112680  0.428
1986 Larson R, Williams S, Le Beau M, Bitter M, Vardiman J, Rowley J. Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis Blood. 68: 1242-1249. DOI: 10.1182/blood.V68.6.1242.bloodjournal6861242  0.313
1986 Le Beau M. Chromosomal fragile sites and cancer-specific rearrangements Blood. 67: 849-858. DOI: 10.1182/blood.v67.4.849.849  0.307
1985 Diaz MO, Le Beau MM, Harden A, Rowley JD. Trisomy 8 in human hematologic neoplasia and the c-myc and c-mos oncogenes. Leukemia Research. 9: 1437-42. PMID 4079453 DOI: 10.1016/0145-2126(85)90033-5  0.302
1985 Westbrook CA, Le Beau MM, Diaz MO, Groffen J, Rowley JD. Chromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 82: 8742-6. PMID 3866248 DOI: 10.1073/Pnas.82.24.8742  0.392
1985 Diaz MO, Le Beau MM, Rowley JD, Drabkin HA, Patterson D. The role of the c-mos gene in the 8;21 translocation in human acute myeloblastic leukemia Science. 229: 767-769. PMID 3860954 DOI: 10.1126/science.3860954  0.4
1985 Le Beau MM, Bitter MA, Kaneko Y, Ueshima Y, Rowley JD. Insertion (10;11)(p11;q23q24) in two cases of acute monocytic leukemia. Leukemia Research. 9: 605-11. PMID 3859710 DOI: 10.1016/0145-2126(85)90140-7  0.336
1985 Suarez CR, Le Beau MM, Silberman S, Fresco R, Rowley JD. Acute megakaryoblastic leukemia in Down's syndrome: report of a case and review of cytogenetic findings. Medical and Pediatric Oncology. 13: 225-31. PMID 3159953 DOI: 10.1002/mpo.2950130413  0.344
1985 Drabkin HA, Diaz M, Bradley CM, Le Beau MM, Rowley JD, Patterson D. Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: Evidence that c-mos is not translocated Proceedings of the National Academy of Sciences of the United States of America. 82: 464-468. PMID 2982159 DOI: 10.1073/pnas.82.2.464  0.455
1985 Le Beau MM, Westbrook CA, Diaz MO, Rowley JD. c-src is consistently conserved in the chromosomal deletion (20q) observed in myeloid disorders. Proceedings of the National Academy of Sciences of the United States of America. 82: 6692-6. PMID 2413444 DOI: 10.1073/Pnas.82.19.6692  0.433
1985 Bitter M, Neilly M, Le Beau M, Pearson M, Rowley J. Rearrangements of chromosome 3 involving bands 3q21 and 3q26 are associated with normal or elevated platelet counts in acute nonlymphocytic leukemia Blood. 66: 1362-1370. DOI: 10.1182/blood.v66.6.1362.1362  0.319
1983 Albain KS, Le Beau MM, Vardiman JW, Golomb HM, Rowley JD. Development of dysmyelopoietic syndrome in a hairy cell leukemia patient treated with chlorambucil: cytogenetic and morphologic evaluation. Cancer Genetics and Cytogenetics. 8: 107-15. PMID 6825062 DOI: 10.1016/0165-4608(83)90042-0  0.398
1983 Le Beau MM, Larson RA, Bitter MA, Vardiman JW, Golomb HM, Rowley JD. Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association. The New England Journal of Medicine. 309: 630-6. PMID 6577285 DOI: 10.1056/NEJM198309153091103  0.304
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