Luda Diatchenko - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Molecular Genetics of Pain Perception
Website:
http://genomics.unc.edu/diatchenko/diatchenko.htm

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bang S, Jiang C, Xu J, Chandra S, McGinnis A, Luo X, He Q, Li Y, Wang Z, Ao X, Parisien M, Oliveira Fernandes de Araujo L, Jahangiri Esfahani S, Zhang Q, Tonello R, ... ... Diatchenko L, et al. Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis. The Journal of Clinical Investigation. PMID 38530364 DOI: 10.1172/JCI173537  0.402
2023 Bang S, Jiang C, Xu J, Chandra S, McGinnis A, Luo X, He Q, Li Y, Wang Z, Ao X, Parisien M, Fernandes de Araujo LO, Esfahan SJ, Zhang Q, Tonello R, ... ... Diatchenko L, et al. Satellite glial GPR37L1 regulates maresin and potassium channel signaling for pain control. Biorxiv : the Preprint Server For Biology. PMID 38106084 DOI: 10.1101/2023.12.03.569787  0.387
2023 Ao X, Parisien M, Fillingim RB, Ohrbach R, Slade GD, Diatchenko L, Smith SB. Whole-genome methylation profiling reveals regions associated with painful temporomandibular disorders and active recovery processes. Pain. PMID 38015635 DOI: 10.1097/j.pain.0000000000003104  0.627
2023 Zorina-Lichtenwalter K, Ase AR, Verma V, Parra AIM, Komarova S, Khadra A, Séguéla P, Diatchenko L. Characterisation of common genetic variants in P2RX7 and their contribution to chronic pain conditions. The Journal of Pain. PMID 37742908 DOI: 10.1016/j.jpain.2023.09.011  0.472
2023 Tanguay-Sabourin C, Fillingim M, Guglietti GV, Zare A, Parisien M, Norman J, Sweatman H, Da-Ano R, Heikkala E, Perez J, Karppinen J, Villeneuve S, Thompson SJ, Martel MO, Roy M, ... Diatchenko L, et al. A prognostic risk score for development and spread of chronic pain. Nature Medicine. PMID 37414898 DOI: 10.1038/s41591-023-02430-4  0.442
2023 Zhao J, Huh Y, Bortsov A, Diatchenko L, Ji RR. Immunotherapies in chronic pain through modulation of neuroimmune interactions. Pharmacology & Therapeutics. 108476. PMID 37307899 DOI: 10.1016/j.pharmthera.2023.108476  0.388
2023 He BH, Diatchenko L, Ingelmo P. Genetic risk factors for chronic postsurgical pain in children: A narrative review. European Journal of Anaesthesiology. PMID 37199409 DOI: 10.1097/EJA.0000000000001847  0.42
2023 Parisien M, Buxbaum C, Granovsky Y, Yarnitsky D, Diatchenko L. Prospective Blood Transcriptomics Study in a Motor Vehicle Collision Cohort Identified a Protective Function of the SAMD15 Gene Against Chronic Pain. The Journal of Pain. PMID 37116672 DOI: 10.1016/j.jpain.2023.04.009  0.456
2023 Parisien M, van Reij RRI, Khoury S, Koseli E, Karaky M, van den Hoogen NJ, Peng G, Allegri M, de Gregori M, Chelly JE, Rakel BA, Aasvang EK, Kehlet H, Buhre WFFA, Bryant CD, ... ... Diatchenko L, et al. Genome-wide association study suggests a critical contribution of the adaptive immune system to chronic post-surgical pain. Medrxiv : the Preprint Server For Health Sciences. PMID 36945481 DOI: 10.1101/2023.01.24.23284520  0.719
2023 Ao X, Parisien M, Zidan M, Grant AV, Martinsen AE, Winsvold BS, Diatchenko L. Rare variant analyses in large-scale cohorts identified SLC13A1 associated with chronic pain. Pain. PMID 36943258 DOI: 10.1097/j.pain.0000000000002882  0.487
2023 Parisien M, Grant AV, Muralidharan A, Diatchenko L, Mogil JS. Chronic pain and premature mortality in men and women, using data from UK Biobank. Reply. The Journal of Clinical Investigation. 133. PMID 36856114 DOI: 10.1172/JCI168070  0.547
2022 Edwards RR, Schreiber KL, Dworkin RH, Turk DC, Baron R, Freeman R, Jensen TS, Latremoliere A, Markman JD, Rice ASC, Rowbotham M, Staud R, Tate S, Woolf CJ, Andrews NA, ... ... Diatchenko L, et al. Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations. The Journal of Pain. PMID 36198371 DOI: 10.1016/j.jpain.2022.08.010  0.421
2022 Diatchenko L, Parisien M, Jahangiri Esfahani S, Mogil JS. Omics approaches to discover pathophysiological pathways contributing to human pain. Pain. PMID 35994593 DOI: 10.1097/j.pain.0000000000002726  0.618
2022 Bortsov AV, Parisien M, Khoury S, Martinsen AE, Lie MU, Heuch I, Hveem K, Zwart JA, Winsvold BS, Diatchenko L. Brain-specific genes contribute to chronic but not to acute back pain. Pain Reports. 7: e1018. PMID 35975136 DOI: 10.1097/PR9.0000000000001018  0.64
2022 Trendafilova T, Adhikari K, Schmid AB, Patel R, Polgár E, Chisholm KI, Middleton SJ, Boyle K, Dickie AC, Semizoglou E, Perez-Sanchez J, Bell AM, Ramirez-Aristeguieta LM, Khoury S, Ivanov A, ... ... Diatchenko L, et al. Sodium-calcium exchanger-3 regulates pain "wind-up": From human psychophysics to spinal mechanisms. Neuron. PMID 35705078 DOI: 10.1016/j.neuron.2022.05.017  0.571
2022 Wang Y, Benavides R, Diatchenko L, Grant AV, Li Y. A graph-embedded topic model enables characterization of diverse pain phenotypes among UK biobank individuals. Iscience. 25: 104390. PMID 35637735 DOI: 10.1016/j.isci.2022.104390  0.33
2022 Tansley S, Gu N, Guzmán AU, Cai W, Wong C, Lister K, Muñoz-Pino E, Yousefpour N, Roome RB, Heal J, Wu N, Castonguay A, Lean G, Muir EM, Kania A, ... ... Diatchenko L, et al. Microglia-mediated degradation of perineuronal nets promotes pain. Science (New York, N.Y.). eabl6773. PMID 35617374 DOI: 10.1126/science.abl6773  0.549
2022 Parisien M, Lima LV, Dagostino C, El-Hachem N, Drury GL, Grant AV, Huising J, Verma V, Meloto CB, Silva JR, Dutra GGS, Markova T, Dang H, Tessier PA, Slade GD, ... ... Diatchenko L, et al. Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Science Translational Medicine. 14: eabj9954. PMID 35544595 DOI: 10.1126/scitranslmed.abj9954  0.788
2022 Muralidharan A, Sotocinal SG, Yousefpour N, Akkurt N, Lima LV, Tansley S, Parisien M, Wang C, Austin JS, Ham B, Dutra GM, Rousseau P, Maldonado-Bouchard S, Clark T, Rosen SF, ... ... Diatchenko L, et al. Long-term male-specific chronic pain via telomere- and p53‑mediated spinal cord cellular senescence. The Journal of Clinical Investigation. 132. PMID 35426375 DOI: 10.1172/JCI151817  0.618
2022 Tansley S, Uttam S, Ureña Guzmán A, Yaqubi M, Pacis A, Parisien M, Deamond H, Wong C, Rabau O, Brown N, Haglund L, Ouellet J, Santaguida C, Ribeiro-da-Silva A, Tahmasebi S, ... ... Diatchenko L, et al. Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain. Nature Communications. 13: 843. PMID 35149686 DOI: 10.1038/s41467-022-28473-8  0.542
2021 Wotton JM, Peterson E, Flenniken AM, Bains RS, Veeraragavan S, Bower LR, Bubier JA, Parisien M, Bezginov A, Haselimashhadi H, Mason J, Moore MA, Stewart ME, Clary DA, Delbarre DJ, ... ... Diatchenko L, et al. Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen. Pain. 163: 1139-1157. PMID 35552317 DOI: 10.1097/j.pain.0000000000002481  0.384
2021 Khoury S, Parisien M, Thompson SJ, Vachon-Presseau E, Roy M, Martinsen AE, Winsvold BS, Mundal IP, Zwart JA, Kania A, Mogil JS, Diatchenko L. Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions. Brain : a Journal of Neurology. PMID 34788396 DOI: 10.1093/brain/awab359  0.747
2021 Meloto CB, Ingelmo P, Perez EV, Pitt R, González Cárdenas VH, Mohamed N, Sotocinal SG, Bourassa V, Lima LV, Ribeiro-da-Silva A, Mogil JS, Diatchenko L. Mast cell stabilizer ketotifen fumarate reverses inflammatory but not neuropathic-induced mechanical pain in mice. Pain Reports. 6: e902. PMID 34104835 DOI: 10.1097/PR9.0000000000000902  0.629
2021 Muralidharan A, Samoshkin A, Convertino M, Piltonen MH, Gris P, Wang J, Jiang C, Klares R, Linton A, Ji RR, Maixner W, Dokholyan NV, Mogil JS, Diatchenko L. Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane mu-opioid receptor isoforms. British Journal of Pharmacology. PMID 33782947 DOI: 10.1111/bph.15463  0.715
2021 Kupari J, Usoskin D, Parisien M, Lou D, Hu Y, Fatt M, Lönnerberg P, Spångberg M, Eriksson B, Barkas N, Kharchenko PV, Loré K, Khoury S, Diatchenko L, Ernfors P. Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain. Nature Communications. 12: 1510. PMID 33686078 DOI: 10.1038/s41467-021-21725-z  0.587
2020 Gaynor SM, Bortsov A, Bair E, Fillingim RB, Greenspan JD, Ohrbach R, Diatchenko L, Nackley A, Tchivileva IE, Whitehead W, Alonso AA, Buchheit TE, Boortz-Marx RL, Liedtke W, Park JJ, et al. Phenotypic profile clustering pragmatically identifies diagnostically and mechanistically informative subgroups of chronic pain patients. Pain. PMID 33259458 DOI: 10.1097/j.pain.0000000000002153  0.833
2020 Upadhyay U, Zhuang GZ, Diatchenko L, Parisien M, Kang Y, Sarantopoulos KD, Martin ER, Smith SB, Maixner W, Levitt RC. Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 33247772 DOI: 10.1007/s00335-020-09848-y  0.7
2020 Piltonen M, Krokhotin A, Parisien M, Bérubé P, Djambazian H, Sladek R, Dokholyan NV, Shabalina SA, Diatchenko L. Correction to: Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants. Cellular and Molecular Neurobiology. PMID 33201419 DOI: 10.1007/s10571-020-00999-9  0.416
2020 Khoury S, Wang QP, Parisien M, Gris P, Bortsov AV, Linnstaedt SD, McLean SA, Tungate AS, Sofer T, Lee J, Louie T, Redline S, Kaunisto MA, Kalso EA, Munter HM, ... ... Diatchenko L, et al. Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons. Sleep. PMID 33034629 DOI: 10.1093/sleep/zsaa211  0.76
2020 Freidin MB, Tsepilov YA, Stanaway IB, Meng W, Hayward C, Smith BH, Khoury S, Parisien M, Bortsov A, Diatchenko L, Børte S, Winsvold BS, Brumpton BM, Zwart JA, All-In Pain H, et al. Sex- and age-specific genetic analysis of chronic back pain. Pain. PMID 33021770 DOI: 10.1097/j.pain.0000000000002100  0.532
2020 Piltonen M, Krokhotin A, Parisien M, Bérubé P, Djambazian H, Sladek R, Dokholyan NV, Shabalina SA, Diatchenko L. Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants. Cellular and Molecular Neurobiology. PMID 33010019 DOI: 10.1007/s10571-020-00971-7  0.479
2020 van Tilburg MA, Parisien M, Boles RG, Drury GL, Smith-Voudouris J, Verma V, Khoury S, Chabot-Doré AJ, Nackley AG, Smith SB, Whitehead WE, Zolnoun DA, Slade GD, Tchivileva I, Maixner W, ... Diatchenko L, et al. A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia. Pain. PMID 32658146 DOI: 10.1097/J.Pain.0000000000001996  0.839
2020 Pagé GM, Lacasse A, Beaudet N, Choinière M, Deslauriers S, Diatchenko L, Dupuis L, Grégoire S, Hovey R, Leclair E, Leonard G, Meloto CB, Montagna F, Parent A, et al. The Quebec Low Back Pain Study: a protocol for an innovative 2-tier provincial cohort. Pain Reports. 5: e799. PMID 32072095 DOI: 10.1097/PR9.0000000000000799  0.356
2020 Verma V, Khoury S, Parisien M, Cho C, Maixner W, Martin LJ, Diatchenko L. The dichotomous role of epiregulin in pain. Pain. PMID 31917773 DOI: 10.1097/J.Pain.0000000000001792  0.812
2019 Millecamps M, Shi XQ, Piltonen M, Echeverry S, Diatchenko L, Zhang J, Stone LS. The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain. Neurobiology of Aging. PMID 32008855 DOI: 10.1016/j.neurobiolaging.2019.12.018  0.516
2019 Zorina-Lichtenwalter K, Maixner W, Diatchenko L. Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. Pain. PMID 31834199 DOI: 10.1097/j.pain.0000000000001780  0.758
2019 Benavides R, Vsevolozhskaya O, Cattaneo S, Zaykin D, Brenton A, Parisien M, Verma V, Khoury S, Gilron I, Diatchenko L. A functional polymorphism in the ABCB1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients. Pain. PMID 31738228 DOI: 10.1097/J.Pain.0000000000001750  0.658
2019 Slade GD, Rosen JD, Ohrbach R, Greenspan JD, Fillingim RB, Parisien M, Khoury S, Diatchenko L, Maixner W, Bair E. Anatomical selectivity in overlap of chronic facial and bodily pain. Pain Reports. 4: e729. PMID 31583346 DOI: 10.1097/PR9.0000000000000729  0.778
2019 Ohrbach R, Slade G, Bair E, Rathnayaka N, Diatchenko L, Greenspan JD, Maixner W, Fillingim RB. Premorbid and Concurrent Predictors of TMD Onset and Persistence. European Journal of Pain (London, England). PMID 31421009 DOI: 10.1002/Ejp.1472  0.602
2019 Meloto CB, Slade GD, Lichtenwalter RN, Bair E, Rathnayaka N, Diatchenko L, Greenspan JD, Maixner W, Fillingim RB, Ohrbach R. Clinical predictors of persistent temporomandibular disorder in people with first-onset temporomandibular disorder: A prospective case-control study. Journal of the American Dental Association (1939). 150: 572-581.e10. PMID 31248483 DOI: 10.1016/J.Adaj.2019.03.023  0.648
2019 Upadhyay U, Zhuang GZ, Diatchenko L, Parisien M, Kang Y, Sarantopoulos KD, Martin ER, Smith SB, Maixner W, Levitt RC. Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL. Plos Genetics. 15: e1008226. PMID 31199789 DOI: 10.1371/Journal.Pgen.1008226  0.678
2019 Bersellini Farinotti A, Wigerblad G, Nascimento D, Bas DB, Morado Urbina C, Nandakumar KS, Sandor K, Xu B, Abdelmoaty S, Hunt MA, Ängeby Möller K, Baharpoor A, Sinclair J, Jardemark K, Lanner JT, ... ... Diatchenko L, et al. Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. The Journal of Experimental Medicine. PMID 31196979 DOI: 10.1084/Jem.20181657  0.461
2019 Khoury S, Piltonen MH, Ton AT, Cole T, Samoshkin A, Smith SB, Belfer I, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Maixner W, Neely GG, Serohijos AWR, Diatchenko L. A functional substitution in the L-aromatic amino acid decarboxylase enzyme worsens somatic symptoms via a serotonergic pathway. Annals of Neurology. PMID 31177555 DOI: 10.1002/Ana.25521  0.767
2019 Zhu C, Han Q, Samoshkin A, Convertino M, Linton A, Faison EM, Ji RR, Diatchenko L, Dokholyan NV. Stabilization of μ-opioid receptor facilitates its cellular translocation and signaling. Proteins. PMID 31141214 DOI: 10.1002/Prot.25751  0.535
2019 Parisien M, Samoshkin A, Tansley SN, Piltonen MH, Martin LJ, El-Hachem N, Dagostino C, Allegri M, Mogil JS, Khoutorsky A, Diatchenko L. Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain. Pain. PMID 30763288 DOI: 10.1097/j.pain.0000000000001471  0.698
2019 Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, ... ... Diatchenko L, et al. Disentangling the genetics of lean mass. The American Journal of Clinical Nutrition. PMID 30721968 DOI: 10.1093/Ajcn/Nqy272  0.47
2019 Zorina-Lichtenwalter K, Lichtenwalter RN, Zaykin DD, Parisien M, Gravel S, Bortsov A, Diatchenko L. A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect. Human Molecular Genetics. PMID 30657907 DOI: 10.1093/Hmg/Ddz018  0.31
2019 Zwaig J, Goh J, Martel M, Diatchenko L, Khoury S. Poor sleep and chronic pain's effect on physical and psychological well-being from the UK biobank dataset Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.1242  0.421
2019 Goh Y, Khoury S, Velly A, Diatchenko L, Martel M. (330) The Role of Tobacco Smoking in the Transition from Acute to Chronic Pain The Journal of Pain. 20: S57. DOI: 10.1016/J.Jpain.2019.02.026  0.46
2018 Vlaeyen JWS, Maher CG, Wiech K, Van Zundert J, Meloto CB, Diatchenko L, Battié MC, Goossens M, Koes B, Linton SJ. Low back pain. Nature Reviews. Disease Primers. 4: 52. PMID 30546064 DOI: 10.1038/s41572-018-0052-1  0.422
2018 Smith SB, Parisien M, Bair E, Belfer I, Chabot-Doré AJ, Gris P, Khoury S, Tansley S, Torosyan Y, Zaykin DV, Bernhardt O, de Oliveira Serrano P, Gracely RH, Jain D, Järvelin MR, ... ... Diatchenko L, et al. Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. Pain. PMID 30431558 DOI: 10.1097/J.Pain.0000000000001438  0.856
2018 Bortsov AV, Devor M, Kaunisto MA, Kalso E, Brufsky A, Kehlet H, Aasvang E, Bittner R, Diatchenko L, Belfer I. CACNG2 polymorphisms associate with chronic pain following mastectomy. Pain. PMID 30371558 DOI: 10.1097/J.Pain.0000000000001432  0.527
2018 Piltonen M, Parisien M, Grégoire S, Chabot-Doré AJ, Jafarnejad SM, Bérubé P, Djambazian H, Sladek R, Geneau G, Willett P, Stone LS, Shabalina SA, Diatchenko L. Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms. Molecular Neurobiology. PMID 30066306 DOI: 10.1007/s12035-018-1253-z  0.313
2018 Diatchenko L. The human pain genetics database: an interview with Luda Diatchenko. Pain Management. PMID 29869557 DOI: 10.2217/pmt-2018-0028  0.444
2018 Zhuang GZ, Upadhyay U, Tong X, Kang Y, Erasso DM, Fu ES, Sarantopoulos KD, Martin ER, Wiltshire T, Diatchenko L, Smith SB, Maixner W, Levitt RC. Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice. Gene Therapy. PMID 29789638 DOI: 10.1038/S41434-018-0018-7  0.711
2018 Smith S, Parisien M, Gris P, Khoury S, Slade G, Bair E, Fillingim R, Greenspan J, Ohrbach R, Dubner R, Maixner W, Diatchenko L. Genome-wide DNA methylation analysis and integrative bioinformatics in the OPPERA study of painful TMD The Journal of Pain. 19: S100. DOI: 10.1016/J.Jpain.2017.12.224  0.781
2018 Tansley S, Samoshkin A, Parisien M, Piltonen M, Martin L, Mogil J, Diatchenko L, Khoutorsky A. Extracellular matrix mediated plasticity in neuropathic pain The Journal of Pain. 19: S15. DOI: 10.1016/j.jpain.2017.12.068  0.655
2017 Khoury S, Segal J, Parisien M, Noreau A, Dion P, Benavides R, Giguère JF, Denis R, Belfer I, Diatchenko L, Rouleau GA, Lavigne GJ. Post-concussion symptoms and chronic pain after mild traumatic brain injury are modulated by multiple locus effect in the gene through the expression of antisense: A pilot prospective control study. Canadian Journal of Pain = Revue Canadienne De La Douleur. 1: 112-126. PMID 35005347 DOI: 10.1080/24740527.2017.1362942  0.742
2017 Meloto CB, Benavides R, Lichtenwalter RN, Wen X, Tugarinov N, Zorina-Lichtenwalter K, Chabot-Doré AJ, Piltonen MH, Cattaneo S, Verma V, Klares R, Khoury S, Parisien M, Diatchenko L. The Human Pain Genetics Database (HPGDB): a resource dedicated to human pain genetics research. Pain. PMID 29300278 DOI: 10.1097/J.Pain.0000000000001135  0.697
2017 Zorina-Lichtenwalter K, Parisien M, Diatchenko L. Genetic studies of human neuropathic pain conditions: a review. Pain. PMID 29240606 DOI: 10.1097/j.pain.0000000000001099  0.565
2017 Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, ... ... Diatchenko L, et al. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications. 8: 1414. PMID 29116125 DOI: 10.1038/s41467-017-01008-2  0.646
2017 Rosen SF, Ham B, Drouin S, Boachie N, Chabot-Dore AJ, Austin JS, Diatchenko L, Mogil JS. T Cell Mediation of Pregnancy Analgesia Affecting Chronic Pain in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28877966 DOI: 10.1523/JNEUROSCI.2053-17.2017  0.642
2017 Martin LJ, Smith SB, Khoutorsky A, Magnussen CA, Samoshkin A, Sorge RE, Cho C, Yosefpour N, Sivaselvachandran S, Tohyama S, Cole T, Khuong TM, Mir E, Gibson DG, Wieskopf JS, ... ... Diatchenko L, et al. Epiregulin and EGFR interactions are involved in pain processing. The Journal of Clinical Investigation. PMID 28783046 DOI: 10.1172/Jci87406  0.829
2017 Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, ... ... Diatchenko L, et al. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications. 8: 80. PMID 28724990 DOI: 10.1038/S41467-017-00031-7  0.669
2017 Peng C, Li L, Zhang MD, Gonzales CB, Parisien M, Belfer I, Usoskin D, Abdo H, Furlan A, Häring M, Lallemend F, Harkany T, Diatchenko L, Hökfelt T, Hjerling-Leffler J, et al. MiR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. Science (New York, N.Y.). PMID 28572455 DOI: 10.1126/Science.Aam7671  0.511
2017 Parisien M, Khoury S, Chabot-Doré AJ, Sotocinal SG, Slade GD, Smith SB, Fillingim RB, Ohrbach R, Greenspan JD, Maixner W, Mogil JS, Belfer I, Diatchenko L. Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes. Cell Reports. 19: 1940-1952. PMID 28564610 DOI: 10.1016/J.Celrep.2017.05.018  0.854
2017 Levitt RC, Zhuang GY, Kang Y, Erasso DM, Upadhyay U, Ozdemir M, Fu ES, Sarantopoulos KD, Smith SB, Maixner W, Diatchenko L, Martin ER, Wiltshire T. Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 28547032 DOI: 10.1007/S00335-017-9694-7  0.712
2017 Sanders AE, Jain D, Sofer T, Kerr KF, Laurie CC, Shaffer JR, Marazita ML, Kaste LM, Slade GD, Fillingim RB, Ohrbach R, Maixner W, Kocher T, Bernhardt O, Teumer A, ... ... Diatchenko L, et al. GWAS Identifies New Loci for Painful Temporomandibular Disorder. Journal of Dental Research. 22034516686562. PMID 28081371 DOI: 10.1177/0022034516686562  0.722
2017 Khoury S, Segal J, Parisien M, Noreau A, Dion P, Benavides R, Giguère J, Denis R, Belfer I, Diatchenko L, Rouleau GA, Lavigne GJ. Post-concussion symptoms and chronic pain after mild traumatic brain injury are modulated by multiple locus effect in theBDNFgene through the expression of antisense: A pilot prospective control study Canadian Journal of Pain. 1: 112-126. DOI: 10.1080/24740527.2017.1362942  0.466
2017 Khoury S, Parisien M, Wang Q, Neely G, Bortsov A, McLean S, Sofer T, Louie T, Kaunisto M, Kalso E, Belfer I, Slade G, Smith S, Fillingim R, Ohrbach R, ... ... Diatchenko L, et al. Genome wide association study of sleep quality identifies a new association with loci near MPP6 Sleep Medicine. 40: e157-e158. DOI: 10.1016/J.Sleep.2017.11.463  0.596
2016 Linnstaedt SD, Walker MG, Riker KD, Nyland JE, Hu J, Rossi C, Swor RA, Jones JS, Diatchenko L, Bortsov AV, Peak DA, McLean SA. Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site. Pain. PMID 27805929 DOI: 10.1097/J.Pain.0000000000000742  0.403
2016 Slade GD, Ohrbach R, Greenspan JD, Fillingim RB, Bair E, Sanders AE, Dubner R, Diatchenko L, Meloto CB, Smith S, Maixner W. Painful Temporomandibular Disorder: Decade of Discovery from OPPERA Studies. Journal of Dental Research. PMID 27339423 DOI: 10.1177/0022034516653743  0.792
2016 Zorina-Lichtenwalter K, Meloto CB, Khoury S, Diatchenko LB. Genetic predictors of human chronic pain conditions. Neuroscience. PMID 27143481 DOI: 10.1016/j.neuroscience.2016.04.041  0.697
2016 Wang S, Joseph J, Diatchenko L, Ro JY, Chung MK. Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1. Pain. PMID 26967694 DOI: 10.1097/j.pain.0000000000000556  0.368
2016 Bair E, Gaynor S, Slade GD, Ohrbach R, Fillingim RB, Greenspan JD, Dubner R, Smith SB, Diatchenko L, Maixner W. Identification of Clusters of Individuals Relevant to Temporomandibular Disorders and Other Chronic Pain Conditions: The OPPERA Study. Pain. PMID 26928952 DOI: 10.1097/J.Pain.0000000000000518  0.759
2016 De Gregori M, Diatchenko L, Ingelmo PM, Napolioni V, Klepstad P, Belfer I, Molinaro V, Garbin G, Ranzani GN, Alberio G, Normanno M, Lovisari F, Somaini M, Govoni S, Mura E, et al. Human Genetic Variability Contributes to Post-operative Morphine Consumption. The Journal of Pain : Official Journal of the American Pain Society. PMID 26902643 DOI: 10.1016/j.jpain.2016.02.003  0.414
2016 Kambur O, Samoshkin A, Kaunisto M, Wieskopf J, Mogil J, Diatchenko L, Kalso E. ADRB2, pain and opioids in mice and man Scandinavian Journal of Pain. 12: 122-122. DOI: 10.1016/j.sjpain.2016.05.016  0.648
2015 Meloto CB, Bortsov A, Bair E, Helgeson E, Ostrom C, Smith S, Dubner R, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Maixner W, McLean S, Diatchenko L. Modification of COMT-dependent pain sensitivity by psychological stress and sex. Pain. PMID 26675825 DOI: 10.1097/J.Pain.0000000000000449  0.795
2015 Samoshkin A, Convertino M, Viet CT, Wieskopf JS, Kambur O, Marcovitz J, Patel P, Stone LS, Kalso E, Mogil JS, Schmidt BL, Maixner W, Dokholyan NV, Diatchenko L. Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling. Scientific Reports. 5: 18198. PMID 26657998 DOI: 10.1038/Srep18198  0.737
2015 Convertino M, Samoshkin A, Viet CT, Gauthier J, Li Fraine SP, Sharif-Naeini R, Schmidt BL, Maixner W, Diatchenko L, Dokholyan NV. Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation. Plos One. 10: e0142826. PMID 26554831 DOI: 10.1371/Journal.Pone.0142826  0.687
2015 van Hecke O, Kamerman PR, Attal N, Baron R, Bjornsdottir G, Bennett DL, Bennett MI, Bouhassira D, Diatchenko L, Freeman R, Freynhagen R, Haanpää M, Jensen TS, Raja SN, Rice AS, et al. Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations. Pain. 156: 2337-53. PMID 26469320 DOI: 10.1097/J.Pain.0000000000000335  0.55
2015 Martin LJ, Piltonen MH, Gauthier J, Convertino M, Acland EL, Dokholyan NV, Mogil JS, Diatchenko L, Maixner W. Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers. The Journal of Pain : Official Journal of the American Pain Society. PMID 26456674 DOI: 10.1016/J.Jpain.2015.09.004  0.751
2015 Hsu YH, Liu Y, Hannan MT, Maixner W, Smith SB, Diatchenko L, Golightly YM, Menz HB, Kraus VB, Doherty M, Wilson AG, Jordan JM. Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans. Journal of Medical Genetics. PMID 26337638 DOI: 10.1136/Jmedgenet-2015-103142  0.698
2015 Meloto CB, Segall SK, Smith S, Parisien M, Shabalina SA, Rizzatti-Barbosa CM, Gauthier J, Tsao D, Convertino M, Piltonen MH, Slade GD, Fillingim RB, Greenspan JD, Ohrbach R, Knott C, ... ... Diatchenko L, et al. COMT gene locus: new functional variants. Pain. 156: 2072-83. PMID 26207649 DOI: 10.1097/J.Pain.0000000000000273  0.847
2015 Slade GD, Sanders AE, Ohrbach R, Bair E, Maixner W, Greenspan JD, Fillingim RB, Smith S, Diatchenko L. COMT Diplotype Amplifies Effect of Stress on Risk of Temporomandibular Pain. Journal of Dental Research. 94: 1187-95. PMID 26198390 DOI: 10.1177/0022034515595043  0.748
2015 Segall SK, Shabalina SA, Meloto CB, Wen X, Cunningham D, Tarantino LM, Wiltshire T, Gauthier J, Tohyama S, Martin LJ, Mogil JS, Diatchenko L. Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. Pain. PMID 26067582 DOI: 10.1097/J.Pain.0000000000000258  0.773
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Diatchenko L, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/Scitranslmed.3009986  0.812
2015 Zhuang GZ, Keeler B, Grant J, Bianchi L, Fu ES, Zhang YP, Erasso DM, Cui JG, Wiltshire T, Li Q, Hao S, Sarantopoulos KD, Candiotti K, Wishnek SM, Smith SB, ... ... Diatchenko L, et al. Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway. Plos One. 10: e0118273. PMID 25734498 DOI: 10.1371/Journal.Pone.0118273  0.762
2015 Convertino M, Samoshkin A, Gauthier J, Gold MS, Maixner W, Dokholyan NV, Diatchenko L. μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 62: 61-7. PMID 25485963 DOI: 10.1016/J.Pnpbp.2014.11.009  0.685
2015 Huijnen IP, Rusu AC, Scholich S, Meloto CB, Diatchenko L. Subgrouping of low back pain patients for targeting treatments: evidence from genetic, psychological, and activity-related behavioral approaches. The Clinical Journal of Pain. 31: 123-32. PMID 24681821 DOI: 10.1097/AJP.0000000000000100  0.51
2015 Hsu YH, Liu Y, Hannan MT, Maixner W, Smith SB, Diatchenko L, Golightly YM, Menz HB, Kraus VB, Doherty M, Wilson AG, Jordan JM. Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans Journal of Medical Genetics. DOI: 10.1136/jmedgenet-2015-103142  0.672
2015 Smith S, Bair E, Slade G, Ostrum C, Helgeson E, Fillingim R, Greenspan J, Ohrbach R, Dubner R, Maixner W, Diatchenko L. (268) Female-specific effects of a serotonin 2A receptor (HTR2A) genetic variant on TMD pain and psychological phenotypes The Journal of Pain. 16: S43. DOI: 10.1016/J.Jpain.2015.01.185  0.76
2014 Diatchenko L. Translational research in the genomic era: OPPERA study Molecular Pain. 10: 1-2. PMID 25521492 DOI: 10.1186/1744-8069-10-S1-O1  0.546
2014 De Gregori M, Diatchenko L, Belfer I, Allegri M. OPRM1 receptor as new biomarker to help the prediction of post mastectomy pain and recurrence in breast cancer. Minerva Anestesiologica. PMID 25300626  0.352
2014 Smith SB, Reenilä I, Männistö PT, Slade GD, Maixner W, Diatchenko L, Nackley AG. Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain. Pain. 155: 2390-9. PMID 25218601 DOI: 10.1016/J.Pain.2014.09.009  0.849
2014 Bortsov AV, Diatchenko L, McLean SA. Complex multilocus effects of catechol-O-methyltransferase haplotypes predict pain and pain interference 6 weeks after motor vehicle collision. Neuromolecular Medicine. 16: 83-93. PMID 23963787 DOI: 10.1007/S12017-013-8255-9  0.553
2014 Smith SB, Bair E, Xue W, Slade GD, Dubner R, Fillingim RB, Greenspan JD, Ohrbach R, Knott C, Diatchenko L, Maixner W. Association between INADL genetic variant and a subgroup with high risk for TMD in the OPPERA study Molecular Pain. 10: P5. DOI: 10.1186/1744-8069-10-S1-P5  0.747
2014 Levitt RC, Zhuang GZ, Keeler B, Grant J, Bianchi L, Fu ES, Zhang YP, Erasso DM, Cui JG, Wiltshire T, Li Q, Hao S, Sarantopoulos KD, Candiotti K, Smith SB, ... ... Diatchenko L, et al. Carbonic anhydrase-8 gene therapy inhibits the ITPR1-cytosolic free calcium pathway producing analgesia and anti-hyperalgesia Molecular Pain. 10: O7. DOI: 10.1186/1744-8069-10-S1-O7  0.667
2014 Diatchenko L, Fillingim RB, Smith SB, Maixner W. Development New Pain Targets in the Genomic Era Global Spine Journal. 4: s-0034-1376744-s-003. DOI: 10.1055/S-0034-1376744  0.759
2014 Bortsov A, Swift-Scanlan T, Diatchenko L, Swor R, Peak D, Jones J, Rathlev N, Lee D, Domeier R, Hendry P, McLean S. (268) Variable DNA methylation in genes involved in immune response is a potential predictor of chronic widespread pain after motor vehicle collision The Journal of Pain. 15: S43. DOI: 10.1016/J.Jpain.2014.01.177  0.394
2013 Smith SB, Mir E, Bair E, Slade GD, Dubner R, Fillingim RB, Greenspan JD, Ohrbach R, Knott C, Weir B, Maixner W, Diatchenko L. Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T91-101.e1-3. PMID 24275226 DOI: 10.1016/J.Jpain.2013.09.004  0.744
2013 Fillingim RB, Ohrbach R, Greenspan JD, Knott C, Diatchenko L, Dubner R, Bair E, Baraian C, Mack N, Slade GD, Maixner W. Psychological factors associated with development of TMD: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T75-90. PMID 24275225 DOI: 10.1016/J.Jpain.2013.06.009  0.715
2013 Greenspan JD, Slade GD, Bair E, Dubner R, Fillingim RB, Ohrbach R, Knott C, Diatchenko L, Liu Q, Maixner W. Pain sensitivity and autonomic factors associated with development of TMD: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T63-74.e1-6. PMID 24275224 DOI: 10.1016/J.Jpain.2013.06.007  0.753
2013 Ohrbach R, Bair E, Fillingim RB, Gonzalez Y, Gordon SM, Lim PF, Ribeiro-Dasilva M, Diatchenko L, Dubner R, Greenspan JD, Knott C, Maixner W, Smith SB, Slade GD. Clinical orofacial characteristics associated with risk of first-onset TMD: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T33-50. PMID 24275222 DOI: 10.1016/J.Jpain.2013.07.018  0.756
2013 Slade GD, Bair E, Greenspan JD, Dubner R, Fillingim RB, Diatchenko L, Maixner W, Knott C, Ohrbach R. Signs and symptoms of first-onset TMD and sociodemographic predictors of its development: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T20-32.e1-3. PMID 24275221 DOI: 10.1016/J.Jpain.2013.07.014  0.659
2013 Bair E, Brownstein NC, Ohrbach R, Greenspan JD, Dubner R, Fillingim RB, Maixner W, Smith SB, Diatchenko L, Gonzalez Y, Gordon SM, Lim PF, Ribeiro-Dasilva M, Dampier D, Knott C, et al. Study protocol, sample characteristics, and loss to follow-up: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T2-19. PMID 24275220 DOI: 10.1016/J.Jpain.2013.06.006  0.704
2013 Slade GD, Fillingim RB, Sanders AE, Bair E, Greenspan JD, Ohrbach R, Dubner R, Diatchenko L, Smith SB, Knott C, Maixner W. Summary of findings from the OPPERA prospective cohort study of incidence of first-onset temporomandibular disorder: implications and future directions. The Journal of Pain : Official Journal of the American Pain Society. 14: T116-24. PMID 24275219 DOI: 10.1016/J.Jpain.2013.09.010  0.786
2013 Bair E, Ohrbach R, Fillingim RB, Greenspan JD, Dubner R, Diatchenko L, Helgeson E, Knott C, Maixner W, Slade GD. Multivariable modeling of phenotypic risk factors for first-onset TMD: the OPPERA prospective cohort study. The Journal of Pain : Official Journal of the American Pain Society. 14: T102-15. PMID 24275218 DOI: 10.1016/J.Jpain.2013.09.003  0.722
2013 Slade GD, Smith SB, Zaykin DV, Tchivileva IE, Gibson DG, Yuryev A, Mazo I, Bair E, Fillingim R, Ohrbach R, Greenspan J, Maixner W, Diatchenko L. Facial pain with localized and widespread manifestations: separate pathways of vulnerability. Pain. 154: 2335-43. PMID 23867732 DOI: 10.1016/J.Pain.2013.07.009  0.784
2013 Chen H, Nackley A, Miller V, Diatchenko L, Maixner W. Multisystem dysregulation in painful temporomandibular disorders. The Journal of Pain : Official Journal of the American Pain Society. 14: 983-96. PMID 23721875 DOI: 10.1016/j.jpain.2013.03.011  0.834
2013 Bortsov AV, Smith JE, Diatchenko L, Soward AC, Ulirsch JC, Rossi C, Swor RA, Hauda WE, Peak DA, Jones JS, Holbrook D, Rathlev NK, Foley KA, Lee DC, Collette R, et al. Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure. Pain. 154: 1419-26. PMID 23707272 DOI: 10.1016/J.Pain.2013.04.037  0.537
2013 Belfer I, Segall SK, Lariviere WR, Smith SB, Dai F, Slade GD, Rashid NU, Mogil JS, Campbell CM, Edwards RR, Liu Q, Bair E, Maixner W, Diatchenko L. Pain modality- and sex-specific effects of COMT genetic functional variants. Pain. 154: 1368-76. PMID 23701723 DOI: 10.1016/J.Pain.2013.04.028  0.854
2013 Sanders AE, Essick GK, Fillingim R, Knott C, Ohrbach R, Greenspan JD, Diatchenko L, Maixner W, Dubner R, Bair E, Miller VE, Slade GD. Sleep apnea symptoms and risk of temporomandibular disorder: OPPERA cohort. Journal of Dental Research. 92: 70S-7S. PMID 23690360 DOI: 10.1177/0022034513488140  0.616
2013 Diatchenko L, Fillingim RB, Smith SB, Maixner W. The phenotypic and genetic signatures of common musculoskeletal pain conditions. Nature Reviews. Rheumatology. 9: 340-50. PMID 23545734 DOI: 10.1038/Nrrheum.2013.43  0.807
2013 Smith S, Diatchenko L, Palsson O, Kanazawa M, Van Tilburg M, Maixner W, Whitehead W. Genetic association and meta-analysis implicate the ADRB2 adrenergic receptor gene in Irritable Bowel Syndrome (IBS) The Journal of Pain. 14: S41. DOI: 10.1016/J.Jpain.2013.01.498  0.698
2013 Diatchenko L. COMT is a Major Contributor to Pain Perception: From Humans to Rats and Back to Humans Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 77. DOI: 10.1016/B978-0-12-800044-1.00067-2  0.32
2012 Neely GG, Rao S, Costigan M, Mair N, Racz I, Milinkeviciute G, Meixner A, Nayanala S, Griffin RS, Belfer I, Dai F, Smith S, Diatchenko L, Marengo S, Haubner BJ, et al. Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. Plos Genetics. 8: e1003071. PMID 23236288 DOI: 10.1371/Journal.Pgen.1003071  0.781
2012 Chen H, Slade G, Lim PF, Miller V, Maixner W, Diatchenko L. Relationship between temporomandibular disorders, widespread palpation tenderness, and multiple pain conditions: a case-control study. The Journal of Pain : Official Journal of the American Pain Society. 13: 1016-27. PMID 23031401 DOI: 10.1016/J.Jpain.2012.07.011  0.735
2012 Tsao D, Wieskopf JS, Rashid N, Sorge RE, Redler RL, Segall SK, Mogil JS, Maixner W, Dokholyan NV, Diatchenko L. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Molecular Pain. 8: 25. PMID 22500608 DOI: 10.1186/1744-8069-8-25  0.826
2012 Segall SK, Maixner W, Belfer I, Wiltshire T, Seltzer Z, Diatchenko L. Janus molecule I: dichotomous effects of COMT in neuropathic vs nociceptive pain modalities. Cns & Neurological Disorders Drug Targets. 11: 222-35. PMID 22483297 DOI: 10.2174/187152712800672490  0.852
2012 Sorge RE, Trang T, Dorfman R, Smith SB, Beggs S, Ritchie J, Austin JS, Zaykin DV, Vander Meulen H, Costigan M, Herbert TA, Yarkoni-Abitbul M, Tichauer D, Livneh J, Gershon E, ... ... Diatchenko L, et al. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nature Medicine. 18: 595-9. PMID 22447075 DOI: 10.1038/Nm.2710  0.833
2012 Orrey DC, Bortsov AV, Hoskins JM, Shupp JW, Jones SW, Cicuto BJ, Hwang J, Jordan MH, Holmes JH, Haith LR, Roane BM, Diatchenko L, Cairns BA, McLean SA. Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients. Journal of Burn Care & Research : Official Publication of the American Burn Association. 33: 518-23. PMID 22210062 DOI: 10.1097/Bcr.0B013E31823746Ed  0.547
2012 Sanders AE, Maixner W, Nackley AG, Diatchenko L, By K, Miller VE, Slade GD. Excess risk of temporomandibular disorder associated with cigarette smoking in young adults. The Journal of Pain : Official Journal of the American Pain Society. 13: 21-31. PMID 22036516 DOI: 10.1016/J.Jpain.2011.08.003  0.74
2012 Smith SB, Maixner DW, Fillingim RB, Slade G, Gracely RH, Ambrose K, Zaykin DV, Hyde C, John S, Tan K, Maixner W, Diatchenko L. Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. Arthritis and Rheumatism. 64: 584-93. PMID 21905019 DOI: 10.1002/Art.33338  0.758
2011 Wiltshire T, Maixner W, Diatchenko L. Relax, you won't feel the pain. Nature Neuroscience. 14: 1496-7. PMID 22119947 DOI: 10.1038/Nn.2987  0.736
2011 Diatchenko L, Robinson JE, Maixner W. Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids. European Journal of Pain Supplements. 5: 433-438. PMID 22102848 DOI: 10.1016/J.Eujps.2011.08.022  0.643
2011 Serohijos AW, Yin S, Ding F, Gauthier J, Gibson DG, Maixner W, Dokholyan NV, Diatchenko L. Structural basis for μ-opioid receptor binding and activation. Structure (London, England : 1993). 19: 1683-90. PMID 22078567 DOI: 10.1016/J.Str.2011.08.003  0.678
2011 Smith SB, Maixner DW, Greenspan JD, Dubner R, Fillingim RB, Ohrbach R, Knott C, Slade GD, Bair E, Gibson DG, Zaykin DV, Weir BS, Maixner W, Diatchenko L. Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. The Journal of Pain : Official Journal of the American Pain Society. 12: T92-101. PMID 22074755 DOI: 10.1016/J.Jpain.2011.08.005  0.785
2011 Maixner W, Greenspan JD, Dubner R, Bair E, Mulkey F, Miller V, Knott C, Slade GD, Ohrbach R, Diatchenko L, Fillingim RB. Potential autonomic risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study. The Journal of Pain : Official Journal of the American Pain Society. 12: T75-91. PMID 22074754 DOI: 10.1016/j.jpain.2011.09.002  0.661
2011 Maixner W, Diatchenko L, Dubner R, Fillingim RB, Greenspan JD, Knott C, Ohrbach R, Weir B, Slade GD. Orofacial pain prospective evaluation and risk assessment study--the OPPERA study. The Journal of Pain : Official Journal of the American Pain Society. 12: T4-11.e1-2. PMID 22074751 DOI: 10.1016/J.Jpain.2011.08.002  0.738
2011 Slade GD, Bair E, By K, Mulkey F, Baraian C, Rothwell R, Reynolds M, Miller V, Gonzalez Y, Gordon S, Ribeiro-Dasilva M, Lim PF, Greenspan JD, Dubner R, Fillingim RB, ... Diatchenko L, et al. Study methods, recruitment, sociodemographic findings, and demographic representativeness in the OPPERA study. The Journal of Pain : Official Journal of the American Pain Society. 12: T12-26. PMID 22074749 DOI: 10.1016/J.Jpain.2011.08.001  0.644
2011 Fillingim RB, Slade GD, Diatchenko L, Dubner R, Greenspan JD, Knott C, Ohrbach R, Maixner W. Summary of findings from the OPPERA baseline case-control study: implications and future directions. The Journal of Pain : Official Journal of the American Pain Society. 12: T102-7. PMID 22074748 DOI: 10.1016/J.Jpain.2011.08.009  0.715
2011 Slade GD, Conrad MS, Diatchenko L, Rashid NU, Zhong S, Smith S, Rhodes J, Medvedev A, Makarov S, Maixner W, Nackley AG. Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness. Pain. 152: 2802-12. PMID 22000099 DOI: 10.1016/J.Pain.2011.09.005  0.819
2011 Tsao D, Diatchenko L, Dokholyan NV. Structural mechanism of S-adenosyl methionine binding to catechol O-methyltransferase. Plos One. 6: e24287. PMID 21904625 DOI: 10.1371/Journal.Pone.0024287  0.64
2011 Tsao D, Shabalina SA, Gauthier J, Dokholyan NV, Diatchenko L. Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant. Nucleic Acids Research. 39: 6201-12. PMID 21486747 DOI: 10.1016/J.Jpain.2011.02.129  0.69
2011 McLean SA, Diatchenko L, Lee YM, Swor RA, Domeier RM, Jones JS, Jones CW, Reed C, Harris RE, Maixner W, Clauw DJ, Liberzon I. Catechol O-methyltransferase haplotype predicts immediate musculoskeletal neck pain and psychological symptoms after motor vehicle collision. The Journal of Pain : Official Journal of the American Pain Society. 12: 101-7. PMID 20688576 DOI: 10.1016/J.Jpain.2010.05.008  0.756
2011 Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, et al. Multiple chronic pain states are associated with a common amino acid changing allele in KCNS1 (vol 133, pg 2519, 2010) Brain. 134. DOI: 10.1093/Brain/Awq387  0.762
2011 Orrey D, Shupp J, Hoskins J, Platts-Mills T, Bortsov A, Bangdiwala S, Haith L, Diatchenko L, Holmes J, Jordan M, Cairns B, McLean S. Pilot multicenter, genotype-based, randomized, double-blind, placebo-controlled trial of propranolol to reduce initial pain symptoms in patients with major burn injury The Journal of Pain. 12: P46. DOI: 10.1016/J.Jpain.2011.02.186  0.388
2011 Chen H, Slade G, Maixner W, Miller V, Diatchenko L. Widespread palpation tenderness is associated with multiple pain conditions in females with temporomandibular disorders The Journal of Pain. 12: P18. DOI: 10.1016/J.Jpain.2011.02.071  0.721
2010 Neely GG, Hess A, Costigan M, Keene AC, Goulas S, Langeslag M, Griffin RS, Belfer I, Dai F, Smith SB, Diatchenko L, Gupta V, Xia CP, Amann S, Kreitz S, et al. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell. 143: 628-38. PMID 21074052 DOI: 10.1016/J.Cell.2010.09.047  0.784
2010 Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, et al. Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain : a Journal of Neurology. 133: 2519-27. PMID 20724292 DOI: 10.1093/Brain/Awq195  0.822
2010 Segall SK, Nackley AG, Diatchenko L, Lariviere WR, Lu X, Marron JS, Grabowski-Boase L, Walker JR, Slade G, Gauthier J, Bailey JS, Steffy BM, Maynard TM, Tarantino LM, Wiltshire T. Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice. Genes, Brain, and Behavior. 9: 933-46. PMID 20659173 DOI: 10.1111/J.1601-183X.2010.00633.X  0.822
2010 Gris P, Gauthier J, Cheng P, Gibson DG, Gris D, Laur O, Pierson J, Wentworth S, Nackley AG, Maixner W, Diatchenko L. A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism. Molecular Pain. 6: 33. PMID 20525224 DOI: 10.1186/1744-8069-6-33  0.76
2010 Gris P, Cheng P, Pierson J, Maixner W, Diatchenko L. Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR). Methods in Molecular Biology (Clifton, N.J.). 617: 421-35. PMID 20336438 DOI: 10.1007/978-1-60327-323-7_30  0.648
2010 Nackley AG, Diatchenko L. Assessing potential functionality of catechol-O-methyltransferase (COMT) polymorphisms associated with pain sensitivity and temporomandibular joint disorders. Methods in Molecular Biology (Clifton, N.J.). 617: 375-93. PMID 20336436 DOI: 10.1007/978-1-60327-323-7_28  0.74
2010 Tchivileva IE, Lim PF, Smith SB, Slade GD, Diatchenko L, McLean SA, Maixner W. Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study. Pharmacogenetics and Genomics. 20: 239-48. PMID 20216107 DOI: 10.1097/Fpc.0B013E328337F9Ab  0.801
2010 Reimann F, Cox JJ, Belfer I, Diatchenko L, Zaykin DV, McHale DP, Drenth JP, Dai F, Wheeler J, Sanders F, Wood L, Wu TX, Karppinen J, Nikolajsen L, Männikkö M, et al. Pain perception is altered by a nucleotide polymorphism in SCN9A. Proceedings of the National Academy of Sciences of the United States of America. 107: 5148-53. PMID 20212137 DOI: 10.1073/Pnas.0913181107  0.827
2010 Nackley A, Conrad M, Slade G, Smith S, Gibson D, Kasravi P, Miller V, Lim P, Maixner W, Diatchenko L. Cytokines associated with TMD case status and related intermediate phenotypes The Journal of Pain. 11: S18. DOI: 10.1016/J.Jpain.2010.01.077  0.771
2009 Tchivileva IE, Tan KS, Gambarian M, Nackley AG, Medvedev AV, Romanov S, Flood PM, Maixner W, Makarov SS, Diatchenko L. Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytes. Molecular Immunology. 46: 2256-66. PMID 19477016 DOI: 10.1016/J.Molimm.2009.04.008  0.728
2009 Nackley AG, Shabalina SA, Lambert JE, Conrad MS, Gibson DG, Spiridonov AN, Satterfield SK, Diatchenko L. Low enzymatic activity haplotypes of the human catechol-O-methyltransferase gene: enrichment for marker SNPs. Plos One. 4: e5237. PMID 19365560 DOI: 10.1371/journal.pone.0005237  0.706
2009 Tchivileva IE, Nackley AG, Qian L, Wentworth S, Conrad M, Diatchenko LB. Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase. Molecular Pain. 5: 13. PMID 19291302 DOI: 10.1186/1744-8069-5-13  0.703
2009 Shabalina SA, Zaykin DV, Gris P, Ogurtsov AY, Gauthier J, Shibata K, Tchivileva IE, Belfer I, Mishra B, Kiselycznyk C, Wallace MR, Staud R, Spiridonov NA, Max MB, Goldman D, ... ... Diatchenko L, et al. Expansion of the human mu-opioid receptor gene architecture: novel functional variants. Human Molecular Genetics. 18: 1037-51. PMID 19103668 DOI: 10.1093/Hmg/Ddn439  0.751
2009 Shibata K, Diatchenko L, Zaykin DV. Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects. Genetic Epidemiology. 33: 63-78. PMID 18636529 DOI: 10.1002/gepi.20358  0.323
2009 Tchivileva I, Lim P, Kasravi P, Gibson D, Smith S, Diatchenko L, Maixner W, McLean S. Propranolol in TMJD treatment The Journal of Pain. 10: S41. DOI: 10.1016/J.Jpain.2009.01.172  0.636
2009 Smith S, Fillingim R, Greenspan J, Ohrbach R, Slade G, Knott C, Weir B, Maixner D, Diatchenko L, Maixner W. Candidate genes associated with psychological risk factors for chronic pain – preliminary findings from the multisite OPPERA cohort study The Journal of Pain. 10: S21. DOI: 10.1016/J.Jpain.2009.01.091  0.779
2008 Slade GD, Diatchenko L, Ohrbach R, Maixner W. Orthodontic Treatment, Genetic Factors and Risk of Temporomandibular Disorder. Seminars in Orthodontics. 14: 146-156. PMID 18663384 DOI: 10.1053/j.sodo.2008.02.005  0.694
2008 Conrad M, Arunasalam R, Gibson D, Bair E, Smith S, Slade G, Maixner W, Diatchenko L, Nackley A. (169) Proinflammatory cytokine profiles associated with TMD case status and related intermediate phenotypes The Journal of Pain. 9: 18. DOI: 10.1016/J.Jpain.2008.01.089  0.769
2008 McLean S, Diatchenko L, Reed C, Jones C, Zaleski E, Mistry Y, Swor R, Sochor M, Liberzon I, Clauw D, Maixner W. (128) Catechol O-Methyltransferase (COMT) met/met genotype influences cortisol response and pain symptoms after minor motor vehicle collision (MVC) The Journal of Pain. 9: 8. DOI: 10.1016/J.Jpain.2008.01.047  0.65
2008 Gris P, Cheng P, Gauthier J, Shabalina S, Maixner W, Diatchenko L. (101) Functional characterization of the novel alternatively spliced form of mu-opioid receptor OPRM1 The Journal of Pain. 9: 1. DOI: 10.1016/J.JPAIN.2008.01.019  0.606
2007 Diatchenko L, Nackley AG, Tchivileva IE, Shabalina SA, Maixner W. Genetic architecture of human pain perception. Trends in Genetics : Tig. 23: 605-13. PMID 18023497 DOI: 10.1016/j.tig.2007.09.004  0.831
2007 Slade GD, Diatchenko L, Bhalang K, Sigurdsson A, Fillingim RB, Belfer I, Max MB, Goldman D, Maixner W. Influence of psychological factors on risk of temporomandibular disorders. Journal of Dental Research. 86: 1120-5. PMID 17959908 DOI: 10.1177/154405910708601119  0.779
2007 Diatchenko L, Slade GD, Nackley AG, Maixner W. Responses to Drs. Kim and Dionne regarding comments on Diatchenko, et al. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain 2006; 125: 216-24. Pain. 129: 366-370. PMID 17851590 DOI: 10.1016/J.Pain.2007.02.012  0.813
2007 Nackley AG, Tan KS, Fecho K, Flood P, Diatchenko L, Maixner W. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain. 128: 199-208. PMID 17084978 DOI: 10.1016/J.Pain.2006.09.022  0.82
2007 Tan KS, Nackley AG, Satterfield K, Maixner W, Diatchenko L, Flood PM. Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms. Cellular Signalling. 19: 251-60. PMID 16996249 DOI: 10.1016/J.Cellsig.2006.06.007  0.724
2007 Nackley A, Tchivileva I, Conrad M, Cooke B, Maixner W, Diatchenko L. (649) The Journal of Pain. 8: S13. DOI: 10.1016/j.jpain.2007.02.060  0.733
2007 Tchivileva I, Nackley A, Maixner W, Diatchenko L. (610) The Journal of Pain. 8: S3. DOI: 10.1016/j.jpain.2007.02.012  0.733
2007 Smith S, Slade G, Belfer I, Goldman D, Max M, Fillingim R, Higgins T, Sama S, Maixner W, Diatchenko L. (607) The Journal of Pain. 8: S2. DOI: 10.1016/J.Jpain.2007.02.009  0.726
2006 Nackley AG, Shabalina SA, Tchivileva IE, Satterfield K, Korchynskyi O, Makarov SS, Maixner W, Diatchenko L. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science (New York, N.Y.). 314: 1930-3. PMID 17185601 DOI: 10.1126/science.1131262  0.792
2006 Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, et al. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nature Medicine. 12: 1269-77. PMID 17057711 DOI: 10.1038/Nm1490  0.798
2006 Diatchenko L, Nackley AG, Slade GD, Bhalang K, Belfer I, Max MB, Goldman D, Maixner W. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain. 125: 216-24. PMID 16837133 DOI: 10.1016/J.Pain.2006.05.024  0.856
2006 Diatchenko L, Nackley AG, Slade GD, Fillingim RB, Maixner W. Idiopathic pain disorders--pathways of vulnerability. Pain. 123: 226-30. PMID 16777329 DOI: 10.1016/J.Pain.2006.04.015  0.813
2006 Diatchenko L, Anderson AD, Slade GD, Fillingim RB, Shabalina SA, Higgins TJ, Sama S, Belfer I, Goldman D, Max MB, Weir BS, Maixner W. Three major haplotypes of the beta2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 449-62. PMID 16741943 DOI: 10.1002/Ajmg.B.30324  0.773
2006 Nackley A, Diatchenko L, Maixner W. Perspectives on the genetic basis of opioid-induced hyperalgesia. Anesthesiology. 104: 909-10. PMID 16645440 DOI: 10.1097/00000542-200605000-00004  0.742
2005 Diatchenko L, Slade GD, Nackley AG, Bhalang K, Sigurdsson A, Belfer I, Goldman D, Xu K, Shabalina SA, Shagin D, Max MB, Makarov SS, Maixner W. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Human Molecular Genetics. 14: 135-43. PMID 15537663 DOI: 10.1093/Hmg/Ddi013  0.858
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