Emmanuelle Passegué - Publications

Affiliations: 
2005-2016 Biomedical Sciences University of California, San Francisco, San Francisco, CA 
 2017- Stem Cell Initiative Columbia University Medical Center, New York University School of Medicine 
Area:
Stem Cell, Genetics, Medicine and Surgery, Biochemistry, Oncology
Website:
https://www.stemcell.columbia.edu/profile/emmanuelle-passegue-phd

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Dellorusso PV, Proven MA, Calero-Nieto FJ, Wang X, Mitchell CA, Hartmann F, Amouzgar M, Favaro P, DeVilbiss A, Swann JW, Ho TT, Zhao Z, Bendall SC, Morrison S, Göttgens B, et al. Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells. Cell Stem Cell. PMID 38754428 DOI: 10.1016/j.stem.2024.04.020  0.831
2024 Swann JW, Olson OC, Passegué E. Made to order: emergency myelopoiesis and demand-adapted innate immune cell production. Nature Reviews. Immunology. PMID 38467802 DOI: 10.1038/s41577-024-00998-7  0.818
2024 Collins A, Swann JW, Proven MA, Patel CM, Mitchell CA, Kasbekar M, Dellorusso PV, Passegué E. Maternal inflammation regulates fetal emergency myelopoiesis. Cell. PMID 38428422 DOI: 10.1016/j.cell.2024.02.002  0.806
2023 Looney M, Conrad C, Magnen M, Tsui J, Wismer H, Naser M, Venkataramani U, Samad B, Cleary S, Qiu L, Tian J, De Giovanni M, Mende N, Passegue E, Laurenti E, et al. Functional haematopoietic progenitor cells in the adult human lung. Research Square. PMID 38077002 DOI: 10.21203/rs.3.rs-3576483/v1  0.355
2023 LaMarche NM, Hegde S, Park MD, Maier BB, Troncoso L, Le Berichel J, Hamon P, Belabed M, Mattiuz R, Hennequin C, Chin T, Reid AM, Reyes-Torres I, Nemeth E, Zhang R, et al. An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. Nature. PMID 38057662 DOI: 10.1038/s41586-023-06797-9  0.789
2023 Kasbekar M, Mitchell CA, Proven MA, Passegué E. Hematopoietic stem cells through the ages: A lifetime of adaptation to organismal demands. Cell Stem Cell. PMID 37865087 DOI: 10.1016/j.stem.2023.09.013  0.698
2023 Collins A, Swann JW, Proven MA, Patel CM, Mitchell CA, Kasbekar M, Dellorusso PV, Passegué E. Maternal IL-10 restricts fetal emergency myelopoiesis. Biorxiv : the Preprint Server For Biology. PMID 37745377 DOI: 10.1101/2023.09.13.557548  0.804
2023 Dellorusso PV, Proven MA, Calero-Nieto FJ, Wang X, Mitchell CA, Hartmann F, Amouzgar M, Favaro P, DeVilbiss A, Swann JW, Ho TT, Zhao Z, Bendall SC, Morrison S, Göttgens B, et al. Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells. Biorxiv : the Preprint Server For Biology. PMID 37645930 DOI: 10.1101/2023.08.17.553736  0.831
2023 Kang YA, Paik H, Zhang SY, Chen JJ, Olson OC, Mitchell CA, Collins A, Swann JW, Warr MR, Fan R, Passegué E. Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production. The Journal of Experimental Medicine. 220. PMID 37115584 DOI: 10.1084/jem.20230088  0.842
2023 Mitchell CA, Verovskaya EV, Calero-Nieto FJ, Olson OC, Swann JW, Wang X, Hérault A, Dellorusso PV, Zhang SY, Svendsen AF, Pietras EM, Bakker ST, Ho TT, Göttgens B, Passegué E. Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing. Nature Cell Biology. PMID 36650381 DOI: 10.1038/s41556-022-01053-0  0.809
2021 Collins A, Mitchell CA, Passegué E. Inflammatory signaling regulates hematopoietic stem and progenitor cell development and homeostasis. The Journal of Experimental Medicine. 218. PMID 34129018 DOI: 10.1084/jem.20201545  0.682
2021 Ho TT, Dellorusso PV, Verovskaya EV, Bakker ST, Flach J, Smith LK, Ventura PB, Lansinger OM, Hérault A, Zhang SY, Kang YA, Mitchell CA, Villeda SA, Passegué E. Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions. The Journal of Experimental Medicine. 218. PMID 34032859 DOI: 10.1084/jem.20210223  0.8
2020 Smith LK, Verovskaya E, Bieri G, Horowitz AM, von Ungern-Sternberg SNI, Lin K, Seizer P, Passegué E, Villeda SA. The aged hematopoietic system promotes hippocampal-dependent cognitive decline. Aging Cell. 19: e13192. PMID 33073926 DOI: 10.1111/Acel.13192  0.797
2020 Yamashita M, Dellorusso PV, Olson OC, Passegué E. Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis. Nature Reviews. Cancer. PMID 32415283 DOI: 10.1038/S41568-020-0260-3  0.845
2020 Olson OC, Kang YA, Passegué E. Normal Hematopoiesis Is a Balancing Act of Self-Renewal and Regeneration. Cold Spring Harbor Perspectives in Medicine. PMID 31988205 DOI: 10.1101/Cshperspect.A035519  0.825
2020 Kang YA, Pietras EM, Passegué E. Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia. The Journal of Experimental Medicine. 217. PMID 31886826 DOI: 10.1084/Jem.20190787  0.796
2020 Smith LK, Verovskaya E, Bieri G, Horowitz AM, von Ungern‐Sternberg SNI, Lin K, Seizer P, Passegué E, Villeda SA. The aged hematopoietic system promotes hippocampal‐dependent cognitive decline Aging Cell. 19. DOI: 10.1111/acel.13192  0.753
2019 Cable J, Fuchs E, Weissman I, Jasper H, Glass D, Rando TA, Blau H, Debnath S, Oliva A, Park S, Passegué E, Kim C, Krasnow MA. Adult stem cells and regenerative medicine-a symposium report. Annals of the New York Academy of Sciences. PMID 31655007 DOI: 10.1111/Nyas.14243  0.603
2019 Yamashita M, Passegué E. TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell. PMID 31230859 DOI: 10.1016/J.Stem.2019.05.019  0.699
2019 Verovskaya EV, Dellorusso PV, Passegué E. Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation. Trends in Molecular Medicine. PMID 31109796 DOI: 10.1016/J.Molmed.2019.04.006  0.847
2018 Gaillard C, Surianarayanan S, Bentley T, Warr MR, Fitch B, Geng H, Passegué E, de Thé H, Kogan SC. Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia. Blood Advances. 2: 2462-2466. PMID 30266821 DOI: 10.1182/bloodadvances.2018018929  0.759
2018 Leeman DS, Hebestreit K, Ruetz T, Webb AE, McKay A, Pollina EA, Dulken BW, Zhao X, Yeo RW, Ho TT, Mahmoudi S, Devarajan K, Passegué E, Rando TA, Frydman J, et al. Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging. Science (New York, N.Y.). 359: 1277-1283. PMID 29590078 DOI: 10.1126/Science.Aag3048  0.775
2018 Verovskaya E, Calero-Nieto F, Reynaud D, Zhang SY, Herault A, Bakker S, Pietras E, Svendsen AF, Wang X, Kinston S, Ho T, Göttgens B, Passegue E. Inflammatory Changes in the Bone Marrow Microenvironment Drive Both Niche and Blood System Remodeling during Aging Experimental Hematology. 64: S43-S44. DOI: 10.1016/J.Exphem.2018.06.048  0.787
2017 Hérault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang YA, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Göttgens B, Passegué E. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. PMID 28355185 DOI: 10.1038/Nature21693  0.808
2017 Lefrançais E, Ortiz-Muñoz G, Caudrillier A, Mallavia B, Liu F, Sayah DM, Thornton EE, Headley MB, David T, Coughlin SR, Krummel MF, Leavitt AD, Passegué E, Looney MR. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors. Nature. PMID 28329764 DOI: 10.1038/Nature21706  0.331
2017 Ho TT, Warr MR, Adelman ER, Lansinger OM, Flach J, Verovskaya EV, Figueroa ME, Passegué E. Autophagy maintains the metabolism and function of young and old stem cells. Nature. PMID 28241143 DOI: 10.1038/Nature21388  0.843
2017 Yamashita M, Passegué E. Inflammation-Produced TNFα± Protects Hematopoietic Stem Cells from Necroptosis via Canonical NF-κB Pathway Blood. 130: 631-631. DOI: 10.1182/Blood.V130.Suppl_1.631.631  0.708
2017 Kang Y, Chen J, Paik H, Zhang S, Warr M, Fan R, Passegué E. Myeloid-biased multipotent progenitors are secretory cells that control myelopoiesis Experimental Hematology. 53. DOI: 10.1016/J.Exphem.2017.06.053  0.653
2016 Beyaz S, Kim JH, Pinello L, Xifaras ME, Hu Y, Huang J, Kerenyi MA, Das PP, Barnitz RA, Herault A, Dogum R, Haining WN, Yilmaz ÖH, Passegue E, Yuan GC, et al. The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells. Nature Immunology. PMID 27992400 DOI: 10.1038/Ni.3644  0.785
2016 Chandel NS, Jasper H, Ho TT, Passegué E. Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing. Nature Cell Biology. PMID 27428307 DOI: 10.1038/Ncb3385  0.826
2016 Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nature Cell Biology. PMID 27111842 DOI: 10.1038/Ncb3346  0.735
2016 Campbell TB, Zhang SY, Valencia A, Passegue E. Bone Marrow Stromal Cell Remodeling Is a Common Feature of Diverse Fibrotic Myeloproliferative Neoplasm Models Blood. 128: 25-25. DOI: 10.1182/Blood.V128.22.25.25  0.606
2016 Campbell T, Zhang SY, Valencia A, Passegue E. Targeting the fibrotic bone marrow niche for treatment of myeloproliferative neoplasms Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.246  0.483
2016 Kang Y, Reynaud D, Pietras E, Passegué E. Myeloid-biased multipotent progenitor expansion by deregulated notch and WNT signaling drives myeloid malignancy Experimental Hematology. 44: S83. DOI: 10.1016/J.Exphem.2016.06.167  0.804
2016 Herault A, Binnewies M, Leong S, Calero F, Zhang SY, Pietras E, Chu H, Barry-Holson K, Armstrong S, Göttgens B, Passegue E. Myeloid progenitor cluster formation drives regenerative and leukemic myelopoiesis Experimental Hematology. 44: S79-S80. DOI: 10.1016/J.Exphem.2016.06.157  0.768
2016 Verovskaya E, Reynaud D, Bakker S, Zhang SY, Ho T, Pietras E, Passegué E. Remodeling of the multipotent progenitor (MPP) pool directly contributes to blood aging Experimental Hematology. 44: S54. DOI: 10.1016/J.Exphem.2016.06.079  0.799
2016 Yamashita M, Kohli L, Warr M, Passegué E. Hematopoietic stem cells are protected by NF-KB Pro-survival signals from TNFA-driven necroptosis Experimental Hematology. 44: S50. DOI: 10.1016/J.Exphem.2016.06.069  0.827
2016 Pietras E, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, Lakshminarasimhan R, Chin CP, Techner J, Will B, Nerlov C, Steidl U, Manz M, Schroeder T, Passegué E. The PRO-inflammatory cytokine interleukin-1 is a key regulator of hematopoietic Stem cell fate and function Experimental Hematology. 44: S49. DOI: 10.1016/J.Exphem.2016.06.066  0.736
2015 Ugarte F, Sousae R, Cinquin B, Martin EW, Krietsch J, Sanchez G, Inman M, Tsang H, Warr M, Passegué E, Larabell CA, Forsberg EC. Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells. Stem Cell Reports. 5: 728-740. PMID 26489895 DOI: 10.1016/J.Stemcr.2015.09.009  0.82
2015 Alvarez S, Díaz M, Flach J, Rodriguez-Acebes S, López-Contreras AJ, Martínez D, Cañamero M, Fernández-Capetillo O, Isern J, Passegué E, Méndez J. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nature Communications. 6: 8548. PMID 26456157 DOI: 10.1038/Ncomms9548  0.748
2015 Wong JC, Weinfurtner KM, Alzamora MD, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen SC, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, et al. Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. Elife. 4. PMID 26193121 DOI: 10.7554/Elife.07839  0.799
2015 Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JM, Göttgens B, Passegué E. Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions. Cell Stem Cell. 17: 35-46. PMID 26095048 DOI: 10.1016/J.Stem.2015.05.003  0.848
2015 Gaillard C, Tokuyasu TA, Rosen G, Sotzen J, Vitaliano-Prunier A, Roy R, Passegué E, de Thé H, Figueroa ME, Kogan SC. Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation. Haematologica. 100: 1064-75. PMID 26088929 DOI: 10.3324/Haematol.2014.123018  0.423
2015 Buchner M, Park E, Geng H, Klemm L, Flach J, Passegué E, Schjerven H, Melnick A, Paietta E, Kopanja D, Raychaudhuri P, Müschen M. Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia. Nature Communications. 6: 6471. PMID 25753524 DOI: 10.1038/Ncomms7471  0.707
2015 Schepers K, Campbell TB, Passegué E. Normal and leukemic stem cell niches: insights and therapeutic opportunities. Cell Stem Cell. 16: 254-67. PMID 25748932 DOI: 10.1016/J.Stem.2015.02.014  0.809
2015 Casbon AJ, Reynaud D, Park C, Khuc E, Gan DD, Schepers K, Passegué E, Werb Z. Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 112: E566-75. PMID 25624500 DOI: 10.1073/Pnas.1424927112  0.824
2015 Wong JC, Weinfurtner KM, Alzamora Mdp, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen S, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, et al. Author response: Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis Elife. DOI: 10.7554/Elife.07839.010  0.759
2015 Pietras EM, Mirantes-Barbeito C, Fong S, Loffler D, Kovtonyuk LV, Lakshminarashimhan R, Chin CP, Techner J, Will B, Nerlov C, Steidl U, Manz M, Schroeder T, Passegue E. Interleukin-1 Drives Precocious Myeloid Differentiation of Hematopoietic Stem Cells at the Expense of Self-Renewal Blood. 126: 778-778. DOI: 10.1182/Blood.V126.23.778.778  0.718
2015 Campbell TB, Passegué E. Abstract A38: Remodeling of the malignant bone marrow niche represents a therapeutic target. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A38  0.501
2015 Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JA, Göttgens B, Passegué E. Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions Cell Stem Cell. 17: 35-46. DOI: 10.1016/j.stem.2015.05.003  0.809
2014 Mirantes C, Passegué E, Pietras EM. Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis. Experimental Cell Research. 329: 248-54. PMID 25149680 DOI: 10.1016/J.Yexcr.2014.08.017  0.742
2014 Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 512: 198-202. PMID 25079315 DOI: 10.1038/Nature13619  0.82
2014 Kohli L, Passegué E. Surviving change: the metabolic journey of hematopoietic stem cells. Trends in Cell Biology. 24: 479-87. PMID 24768033 DOI: 10.1016/J.Tcb.2014.04.001  0.844
2014 Pietras EM, Lakshminarasimhan R, Techner JM, Fong S, Flach J, Binnewies M, Passegué E. Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons. The Journal of Experimental Medicine. 211: 245-62. PMID 24493802 DOI: 10.1084/Jem.20131043  0.805
2014 Wong JC, Weinfurtner K, Alzamora P, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen S, Flach J, Reynaud D, Passegue E, Downing JR, Shannon K. Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes Blood. 124: 3247-3247. DOI: 10.1182/Blood.V124.21.3247.3247  0.824
2014 Passegue E, Teitell M, Ding S, Rando T, Belmonte JCI, Ramalho-Santos M, Terzic A, Brunet A, Chandel NS, Bonnet D, Jasper H. Stem cell energetics Cell Metabolism. 20: 922-925. DOI: 10.1016/J.Cmet.2014.11.007  0.484
2013 Bakker ST, Passegué E. Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells. Experimental Hematology. 41: 915-23. PMID 24067363 DOI: 10.1016/J.Exphem.2013.09.007  0.826
2013 Pietras EM, Passegué E. Linking HSCs to their youth. Nature Cell Biology. 15: 885-7. PMID 23907190 DOI: 10.1038/Ncb2817  0.691
2013 Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 13: 285-99. PMID 23850243 DOI: 10.1016/J.Stem.2013.06.009  0.845
2013 Warr MR, Kohli L, Passegué E. Born to survive: autophagy in hematopoietic stem cell maintenance. Cell Cycle (Georgetown, Tex.). 12: 1979-80. PMID 23759583 DOI: 10.4161/Cc.25303  0.842
2013 Li M, Jones L, Gaillard C, Binnewies M, Ochoa R, Garcia E, Lam V, Wei G, Yang W, Lobe C, Hermiston M, Passegué E, Kogan SC. Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations. Leukemia. 27: 1570-3. PMID 23443342 DOI: 10.1038/Leu.2013.15  0.74
2013 Warr MR, Binnewies M, Flach J, Reynaud D, Garg T, Malhotra R, Debnath J, Passegué E. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature. 494: 323-7. PMID 23389440 DOI: 10.1038/Nature11895  0.824
2013 Warr MR, Passegué E. Metabolic makeover for HSCs. Cell Stem Cell. 12: 1-3. PMID 23290130 DOI: 10.1016/J.Stem.2012.12.005  0.794
2013 Derderian C, King C, Togarrati P, Czechowicz A, Lescano N, Reynaud D, Passegue E, Weissman IL, MacKenzie T. In Utero Depletion Of Fetal Host Hematopoietic Stem Cells Improves Engraftment Following Neonatal Transplantation In Mice Blood. 122: 3240-3240. DOI: 10.1182/Blood.V122.21.3240.3240  0.817
2013 Pietras EM, Passegué E. Erratum: Linking HSCs to their youth Nature Cell Biology. 15: 1131-1131. DOI: 10.1038/Ncb2841  0.643
2013 Pietras EM, Fong S, Löffler D, Lakshminarasimhan R, Techner J, Schroeder T, Passegué E. 198 Cytokine. 63: 290. DOI: 10.1016/J.Cyto.2013.06.201  0.733
2012 Schepers K, Hsiao EC, Garg T, Scott MJ, Passegué E. Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice. Blood. 120: 3425-35. PMID 22859604 DOI: 10.1182/Blood-2011-11-395418  0.798
2012 Gaillard CM, Tokuyasu TA, Passegué E, Kogan SC. PML-RARα Deregulates an Unexpectedly Small Number of Genes in Pre-Leukemic Promyelocytes Blood. 120: 3526-3526. DOI: 10.1182/blood.v120.21.3526.3526  0.351
2011 Pietras EM, Warr MR, Passegué E. Cell cycle regulation in hematopoietic stem cells. The Journal of Cell Biology. 195: 709-20. PMID 22123859 DOI: 10.1084/Jem20813Oia34  0.853
2011 Reynaud D, Pietras E, Barry-Holson K, Mir A, Binnewies M, Jeanne M, Sala-Torra O, Radich JP, Passegué E. IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell. 20: 661-73. PMID 22094259 DOI: 10.1016/J.Ccr.2011.10.012  0.832
2011 Garcia D, Warr MR, Martins CP, Brown Swigart L, Passegué E, Evan GI. Validation of MdmX as a therapeutic target for reactivating p53 in tumors. Genes & Development. 25: 1746-57. PMID 21852537 DOI: 10.1101/Gad.16722111  0.731
2011 Warr MR, Pietras EM, Passegué E. Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 681-701. PMID 21412991 DOI: 10.1002/Wsbm.145  0.857
2011 Blanpain C, Mohrin M, Sotiropoulou PA, Passegué E. DNA-damage response in tissue-specific and cancer stem cells. Cell Stem Cell. 8: 16-29. PMID 21211780 DOI: 10.1016/J.Stem.2010.12.012  0.794
2011 Passegué E. Strategies for Genome Repair in Normal and Leukemic Stem Cells Blood. 118: SCI-41-SCI-41. DOI: 10.1182/blood.v118.21.sci-41.sci-41  0.433
2010 Elefanty AG, Blelloch R, Passegué E, Wernig M, Mummery CL. On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell. 7: 443-50. PMID 20887950 DOI: 10.1016/J.Stem.2010.09.002  0.399
2010 Subramanyam D, Belair CD, Barry-Holson KQ, Lin H, Kogan SC, Passegué E, Blelloch R. PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia. Cancer Research. 70: 8792-801. PMID 20861188 DOI: 10.1158/0008-5472.Can-08-4481  0.813
2010 Ragu C, Elain G, Mylonas E, Ottolenghi C, Cagnard N, Daegelen D, Passegué E, Vainchenker W, Bernard OA, Penard-Lacronique V. The transcription factor Srf regulates hematopoietic stem cell adhesion. Blood. 116: 4464-73. PMID 20709909 DOI: 10.1182/Blood-2009-11-251587  0.541
2010 Forsberg EC, Passegué E, Prohaska SS, Wagers AJ, Koeva M, Stuart JM, Weissman IL. Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. Plos One. 5: e8785. PMID 20098702 DOI: 10.1371/Journal.Pone.0008785  0.767
2010 Reynaud D, Pietras E, Jeanne M, Barry-Holson K, Passegue E. Leukemic Hierarchy and Systemic Factors Dictating Disease Evolution In Chronic Myelogenous Leukemia Blood. 116: 886-886. DOI: 10.1182/Blood.V116.21.886.886  0.845
2009 Santaguida M, Schepers K, King B, Sabnis AJ, Forsberg EC, Attema JL, Braun BS, Passegué E. JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal. Cancer Cell. 15: 341-52. PMID 19345332 DOI: 10.1016/J.Ccr.2009.02.016  0.843
2009 Passegué E, Rafii S, Herlyn M. Cancer stem cells are everywhere. Nature Medicine. 15: 23. PMID 19129778 DOI: 10.1038/Nm0109-23  0.443
2009 Mayack SR, Shadrach J, Schepers K, Passegue E, Wagers AJ. Blood stem cells: Regulation by the niche Developmental Biology. 331: 395. DOI: 10.1016/J.Ydbio.2009.05.041  0.83
2008 Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, Butte AJ, Passegué E, Sage J. Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell. 3: 416-28. PMID 18940733 DOI: 10.1016/J.Stem.2008.07.009  0.592
2008 Shen WF, Hu YL, Uttarwar L, Passegue E, Largman C. MicroRNA-126 regulates HOXA9 by binding to the homeobox. Molecular and Cellular Biology. 28: 4609-19. PMID 18474618 DOI: 10.1128/Mcb.01652-07  0.333
2008 Min IM, Pietramaggiori G, Kim FS, Passegué E, Stevenson KE, Wagers AJ. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell Stem Cell. 2: 380-91. PMID 18397757 DOI: 10.1016/J.Stem.2008.01.015  0.713
2008 Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell. 13: 206-20. PMID 18328425 DOI: 10.1016/J.Ccr.2008.01.034  0.37
2008 Rajasekhar VK, Dalerba P, Passegué E, Lagasse E, Najbauer J. The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007. Stem Cells (Dayton, Ohio). 26: 292-8. PMID 17962698 DOI: 10.1634/Stemcells.2007-0647  0.754
2008 Schepers K, Mayack SR, Wagers AJ, Passegue E. Investigating the Complex Interplay Between Leukemic Stem Cells, Their Myeloid Progeny and Cells from the Bone Marrow Microenvironment in Generating Myeloproliferative Diseases Blood. 112: 3564-3564. DOI: 10.1182/Blood.V112.11.3564.3564  0.812
2008 Mohrin M, Bourke E, Morrison C, Passegue E. How Can Hematopoietic Stem Cells and Myeloid Progenitors Become Transformed?. Blood. 112: 1389-1389. DOI: 10.1182/Blood.V112.11.1389.1389  0.789
2008 Santaguida MT, Schepers K, King BC, Passegue E. JunB Limits Hematopoietic Stem Cell (HSC) Functions as a Protective Mechanism against Initiation of Myeloid Malignancy Blood. 112: 1358-1358. DOI: 10.1182/Blood.V112.11.1358.1358  0.854
2007 Hu YL, Passegué E, Fong S, Largman C, Lawrence HJ. Evidence that the Pim1 kinase gene is a direct target of HOXA9. Blood. 109: 4732-8. PMID 17327400 DOI: 10.1182/Blood-2006-08-043356  0.443
2007 Van Meter ME, Díaz-Flores E, Archard JA, Passegué E, Irish JM, Kotecha N, Nolan GP, Shannon K, Braun BS. K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. Blood. 109: 3945-52. PMID 17192389 DOI: 10.1182/Blood-2006-09-047530  0.485
2007 Santaguida M, Schepers K, King B, Passegue E. Deciphering JunB Function in Regulating Hematopoietic Stem Cell Functions. Blood. 110: 777-777. DOI: 10.1182/Blood.V110.11.777.777  0.855
2006 Steidl U, Rosenbauer F, Verhaak RG, Gu X, Ebralidze A, Otu HH, Klippel S, Steidl C, Bruns I, Costa DB, Wagner K, Aivado M, Kobbe G, Valk PJ, Passegué E, et al. Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells. Nature Genetics. 38: 1269-77. PMID 17041602 DOI: 10.1038/Ng1898  0.506
2006 Passegué E. Cancer biology: a game of subversion. Nature. 442: 754-5. PMID 16915276 DOI: 10.1038/442754A  0.477
2006 Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell. 126: 415-26. PMID 16873070 DOI: 10.1016/J.Cell.2006.06.037  0.517
2006 Nyholm SV, Passegue E, Ludington WB, Voskoboynik A, Mitchel K, Weissman IL, De Tomaso AW. fester, A candidate allorecognition receptor from a primitive chordate. Immunity. 25: 163-73. PMID 16860765 DOI: 10.1016/J.Immuni.2006.04.011  0.76
2006 Passegué E, Wagers AJ. Regulating quiescence: new insights into hematopoietic stem cell biology. Developmental Cell. 10: 415-7. PMID 16580989 DOI: 10.1016/J.Devcel.2006.03.002  0.713
2006 Hosen N, Passegue E, Weissman IL. AML1/ETO and PML/RAR α Can Immortalize Committed Myeloid Progenitor Cells In-Vitro but Not Expand Them In-Vivo. Blood. 108: 2544-2544. DOI: 10.1182/Blood.V108.11.2544.2544  0.734
2005 Passegué E, Weisman IL. Leukemic stem cells: where do they come from? Stem Cell Reviews. 1: 181-8. PMID 17142854 DOI: 10.1385/SCR:1:3:181  0.43
2005 Passegué E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. The Journal of Experimental Medicine. 202: 1599-611. PMID 16330818 DOI: 10.1084/Jem.20050967  0.73
2005 Passegué E. Hematopoietic stem cells, leukemic stem cells and chronic myelogenous leukemia. Cell Cycle (Georgetown, Tex.). 4: 266-8. PMID 15655369  0.407
2004 Jamieson CH, Weissman IL, Passegué E. Chronic versus acute myelogenous leukemia: a question of self-renewal. Cancer Cell. 6: 531-3. PMID 15607956 DOI: 10.1016/j.ccr.2004.12.005  0.555
2004 Passegué E, Wagner EF, Weissman IL. JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell. 119: 431-43. PMID 15507213 DOI: 10.1016/J.Cell.2004.10.010  0.687
2004 Passegué E. Hematopoietic Stem Cells, Leukemic Stem Cells and Chronic Myelogenous Leukemia Cell Cycle. 4: 265-267. DOI: 10.4161/Cc.4.2.1489  0.513
2003 Cozzio A, Passegué E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes & Development. 17: 3029-35. PMID 14701873 DOI: 10.1101/Gad.1143403  0.635
2003 Passegué E, Jamieson CH, Ailles LE, Weissman IL. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proceedings of the National Academy of Sciences of the United States of America. 100: 11842-9. PMID 14504387 DOI: 10.1073/pnas.2034201100  0.578
2003 Szremska AP, Kenner L, Weisz E, Ott RG, Passegué E, Artwohl M, Freissmuth M, Stoxreiter R, Theussl HC, Parzer SB, Moriggl R, Wagner EF, Sexl V. JunB inhibits proliferation and transformation in B-lymphoid cells. Blood. 102: 4159-65. PMID 12907453 DOI: 10.1182/Blood-2003-03-0915  0.552
2003 So CW, Karsunky H, Passegué E, Cozzio A, Weissman IL, Cleary ML. MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell. 3: 161-71. PMID 12620410 DOI: 10.1016/S1535-6108(03)00019-9  0.524
2002 Passegué E, Jochum W, Behrens A, Ricci R, Wagner EF. JunB can substitute for Jun in mouse development and cell proliferation. Nature Genetics. 30: 158-66. PMID 11818961 DOI: 10.1038/Ng790  0.456
2001 Jochum W, Passegué E, Wagner EF. AP-1 in mouse development and tumorigenesis. Oncogene. 20: 2401-12. PMID 11402336 DOI: 10.1038/Sj.Onc.1204389  0.478
2001 Passegué E, Jochum W, Schorpp-Kistner M, Möhle-Steinlein U, Wagner EF. Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking junB expression in the myeloid lineage. Cell. 104: 21-32. PMID 11163237 DOI: 10.1016/S0092-8674(01)00188-X  0.54
2000 Passegué E, Wagner EF. JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression. The Embo Journal. 19: 2969-79. PMID 10856241 DOI: 10.1093/Emboj/19.12.2969  0.463
1999 Jochum W, Passegue E, Wagner EF. [Loss of junB expression causes a myeloproliferative syndrome resembling chronic myeloid leukemia]. Verhandlungen Der Deutschen Gesellschaft Fur Pathologie. 83: 216-7. PMID 10714213  0.313
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