John M. Harlan - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Pathology, Cell Biology

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Chow YH, Liu L, Schwartz B, Harlan JM, Schnapp LM. Short communication: adhesion pathways utilized by HIV-infected lymphocytes. Aids Research and Human Retroviruses. 28: 1557-60. PMID 22394260 DOI: 10.1089/Aid.2011.0262  0.303
2012 Gomez IG, Tang J, Wilson CL, Yan W, Heinecke JW, Harlan JM, Raines EW. Metalloproteinase-mediated Shedding of Integrin β2 promotes macrophage efflux from inflammatory sites. The Journal of Biological Chemistry. 287: 4581-9. PMID 22170060 DOI: 10.1074/Jbc.M111.321182  0.325
2011 Handa P, Tupper JC, Jordan KC, Harlan JM. FLIP (Flice-like inhibitory protein) suppresses cytoplasmic double-stranded-RNA-induced apoptosis and NF-κB and IRF3-mediated signaling. Cell Communication and Signaling : Ccs. 9: 16. PMID 21635783 DOI: 10.1186/1478-811X-9-16  0.352
2011 de Claro RA, Zhu X, Tang J, Morgan-Stevenson V, Schwartz BR, Iwata A, Liles WC, Raines EW, Harlan JM. Hematopoietic Fas deficiency does not affect experimental atherosclerotic lesion formation despite inducing a proatherogenic state. The American Journal of Pathology. 178: 2931-7. PMID 21550016 DOI: 10.1016/J.Ajpath.2011.02.011  0.314
2011 Iwata A, de Claro RA, Morgan-Stevenson VL, Tupper JC, Schwartz BR, Liu L, Zhu X, Jordan KC, Winn RK, Harlan JM. Extracellular administration of BCL2 protein reduces apoptosis and improves survival in a murine model of sepsis. Plos One. 6: e14729. PMID 21390214 DOI: 10.1371/Journal.Pone.0014729  0.31
2010 Chow YH, Zhu XD, Liu L, Schwartz BR, Huang XZ, Harlan JM, Schnapp LM. Role of Cdk4 in lymphocyte function and allergen response. Cell Cycle (Georgetown, Tex.). 9: 4922-30. PMID 21150327 DOI: 10.4161/Cc.9.24.14209  0.358
2010 Iwata A, Morgan-Stevenson V, Schwartz B, Liu L, Tupper J, Zhu X, Harlan J, Winn R. Extracellular BCL2 proteins are danger-associated molecular patterns that reduce tissue damage in murine models of ischemia-reperfusion injury. Plos One. 5: e9103. PMID 20161703 DOI: 10.1371/Journal.Pone.0009103  0.312
2009 Becker PS, Kopecky KJ, Wilks AN, Chien S, Harlan JM, Willman CL, Petersdorf SH, Stirewalt DL, Papayannopoulou T, Appelbaum FR. Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia. Blood. 113: 866-74. PMID 18927435 DOI: 10.1182/Blood-2007-12-124818  0.336
2008 Helmers AJ, Lovegrove FE, Harlan JM, Kain KC, Liles WC. Failure of two distinct anti-apoptotic approaches to reduce mortality in experimental cerebral malaria. The American Journal of Tropical Medicine and Hygiene. 79: 823-5. PMID 19052286 DOI: 10.4269/Ajtmh.2008.79.823  0.323
2008 Liu L, Schwartz B, Tsubota Y, Raines E, Kiyokawa H, Yonekawa K, Harlan JM, Schnapp LM. Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 1808-17. PMID 18209078 DOI: 10.4049/Jimmunol.180.3.1808  0.381
2008 Schnapp LM, Liu L, Schwartz B, Chow Y, Tsubota Y, Raines EW, Harlan JM. Novel role of Cdk4 in leukocyte adhesion and trafficking Matrix Biology. 27: 32. DOI: 10.1016/J.Matbio.2008.09.308  0.312
2007 Taylor EL, Li JT, Tupper JC, Rossi AG, Winn RK, Harlan JM. GEA 3162, a peroxynitrite donor, induces Bcl-2-sensitive, p53-independent apoptosis in murine bone marrow cells. Biochemical Pharmacology. 74: 1039-49. PMID 17681284 DOI: 10.1016/J.Bcp.2007.06.028  0.328
2007 Altemeier WA, Zhu X, Berrington WR, Harlan JM, Liles WC. Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway. Journal of Leukocyte Biology. 82: 721-8. PMID 17576821 DOI: 10.1189/Jlb.1006652  0.404
2005 Yonekawa K, Harlan JM. Targeting leukocyte integrins in human diseases. Journal of Leukocyte Biology. 77: 129-40. PMID 15548573 DOI: 10.1189/Jlb.0804460  0.309
2005 Becker PS, Papayannopoulou T, Kopecky KJ, Hanks AN, Harlan JM, Willman CL, Appelbaum FR. Very Late Antigen-4 (VLA-4) Expression by AML Blasts: Correlation of VCAM-1 Binding to Overall Survival. Blood. 106: 2365-2365. DOI: 10.1182/Blood.V106.11.2365.2365  0.328
2004 Bannerman DD, Eiting KT, Winn RK, Harlan JM. FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kappaB activation induced by bacterial lipopolysaccharide. The American Journal of Pathology. 165: 1423-31. PMID 15466406 DOI: 10.1016/S0002-9440(10)63400-1  0.397
2004 Avellino AM, Dailey AT, Harlan JM, Sharar SR, Winn RK, McNutt LD, Kliot M. Blocking of up-regulated ICAM-1 does not prevent macrophage infiltration during Wallerian degeneration of peripheral nerve. Experimental Neurology. 187: 430-44. PMID 15144869 DOI: 10.1016/J.Expneurol.2004.02.004  0.345
2003 Jun JB, Kuechle M, Harlan JM, Elkon KB. Fibroblast and endothelial apoptosis in systemic sclerosis. Current Opinion in Rheumatology. 15: 756-60. PMID 14569206 DOI: 10.1097/00002281-200311000-00012  0.301
2003 Erwert RD, Eiting KT, Tupper JC, Winn RK, Harlan JM, Bannerman DD. Shiga toxin induces decreased expression of the anti-apoptotic protein Mcl-1 concomitant with the onset of endothelial apoptosis. Microbial Pathogenesis. 35: 87-93. PMID 12901848 DOI: 10.1016/S0882-4010(03)00100-1  0.402
2003 Li X, Tupper JC, Bannerman DD, Winn RK, Rhodes CJ, Harlan JM. Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells. Infection and Immunity. 71: 4414-20. PMID 12874320 DOI: 10.1128/Iai.71.8.4414-4420.2003  0.711
2003 Iwata A, Nishio K, Winn RK, Chi EY, Henderson WR, Harlan JM. A broad-spectrum caspase inhibitor attenuates allergic airway inflammation in murine asthma model Journal of Immunology. 170: 3386-3391. PMID 12626599 DOI: 10.4049/Jimmunol.170.6.3386  0.329
2003 Liu CY, Takemasa A, Liles WC, Goodman RB, Jonas M, Rosen H, Chi E, Winn RK, Harlan JM, Chuang PI. Broad-spectrum caspase inhibition paradoxically augments cell death in TNF-alpha -stimulated neutrophils. Blood. 101: 295-304. PMID 12393619 DOI: 10.1182/Blood-2001-12-0266  0.392
2002 Iwata A, Harlan JM, Vedder NB, Winn RK. The caspase inhibitor z-VAD is more effective than CD18 adhesion blockade in reducing muscle ischemia-reperfusion injury: implication for clinical trials. Blood. 100: 2077-80. PMID 12200369 DOI: 10.1182/Blood-2002-03-0752  0.329
2002 Liu L, Schwartz BR, Lin N, Winn RK, Harlan JM. Requirement for RhoA kinase activation in leukocyte de-adhesion. Journal of Immunology (Baltimore, Md. : 1950). 169: 2330-6. PMID 12193698 DOI: 10.4049/Jimmunol.169.5.2330  0.385
2002 Erwert RD, Winn RK, Harlan JM, Bannerman DD. Shiga-like toxin inhibition of FLICE-like inhibitory protein expression sensitizes endothelial cells to bacterial lipopolysaccharide-induced apoptosis. The Journal of Biological Chemistry. 277: 40567-74. PMID 12189147 DOI: 10.1074/Jbc.M206351200  0.4
2002 Liu L, Schwartz BR, Tupper J, Lin N, Winn RK, Harlan JM. The GTPase Rap1 regulates phorbol 12-myristate 13-acetate-stimulated but not ligand-induced beta 1 integrin-dependent leukocyte adhesion. The Journal of Biological Chemistry. 277: 40893-900. PMID 12091396 DOI: 10.1074/Jbc.M206208200  0.388
2002 Bannerman DD, Erwert RD, Winn RK, Harlan JM. TIRAP mediates endotoxin-induced NF-kappaB activation and apoptosis in endothelial cells. Biochemical and Biophysical Research Communications. 295: 157-62. PMID 12083783 DOI: 10.1016/S0006-291X(02)00638-1  0.423
2002 Harlan JM, Winn RK. Leukocyte-endothelial interactions: clinical trials of anti-adhesion therapy. Critical Care Medicine. 30: S214-9. PMID 12004238 DOI: 10.1097/00003246-200205001-00007  0.323
2002 Chuang PI, Morefield S, Liu CY, Chen S, Harlan JM, Willerford DM. Perturbation of B-cell development in mice overexpressing the Bcl-2 homolog A1. Blood. 99: 3350-9. PMID 11964303 DOI: 10.1182/Blood.V99.9.3350  0.318
2002 Li X, Liu L, Tupper JC, Bannerman DD, Winn RK, Sebti SM, Hamilton AD, Harlan JM. Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells. The Journal of Biological Chemistry. 277: 15309-16. PMID 11839765 DOI: 10.1074/Jbc.M201253200  0.721
2002 Bannerman DD, Tupper JC, Kelly JD, Winn RK, Harlan JM. The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta. The Journal of Clinical Investigation. 109: 419-25. PMID 11828002 DOI: 10.1172/Jci14774  0.355
2002 Bannerman DD, Tupper JC, Erwert RD, Winn RK, Harlan JM. Divergence of bacterial lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1. The Journal of Biological Chemistry. 277: 8048-53. PMID 11777917 DOI: 10.1074/Jbc.M111249200  0.412
2001 Bannerman DD, Tupper JC, Ricketts WA, Bennett CF, Winn RK, Harlan JM. A Constitutive Cytoprotective Pathway Protects Endothelial Cells from Lipopolysaccharide-induced Apoptosis Journal of Biological Chemistry. 276: 14924-14932. PMID 11279137 DOI: 10.1074/Jbc.M100819200  0.432
2001 Papayannopoulou T, Priestley GV, Nakamoto B, Zafiropoulos V, Scott LM, Harlan JM. Synergistic mobilization of hemopoietic progenitor cells using concurrent beta1 and beta2 integrin blockade or beta2-deficient mice. Blood. 97: 1282-8. PMID 11222371 DOI: 10.1182/Blood.V97.5.1282  0.325
2000 Pohlman TH, Harlan JM. Adaptive responses of the endothelium to stress. The Journal of Surgical Research. 89: 85-119. PMID 10720457 DOI: 10.1006/Jsre.1999.5801  0.33
2000 Craxton A, Chuang PI, Shu G, Harlan JM, Clark EA. The CD40-inducible Bcl-2 family member A1 protects B cells from antigen receptor-mediated apoptosis. Cellular Immunology. 200: 56-62. PMID 10716883 DOI: 10.1006/Cimm.2000.1616  0.378
2000 Harlan JM. Introduction: anti-adhesion therapy in sickle cell disease Blood. 95: 365-367. DOI: 10.1182/Blood.V95.2.365  0.341
1999 Gamble JR, Meyer GT, Noack L, Furze J, Matthias LJ, Kovach N, Harlan J, Vadas MA. β1 Integrin Activation Inhibits in Vitro Tube Formation: Effects on Cell Migration, Vacuole Coalescence and Lumen Formation Endothelium-Journal of Endothelial Cell Research. 7: 23-34. PMID 10599558 DOI: 10.3109/10623329909165309  0.353
1999 Zen K, Karsan A, Stempien-Otero A, Yee E, Tupper J, Li X, Eunson T, Kay MA, Wilson CB, Winn RK, Harlan JM. NF-kappaB activation is required for human endothelial survival during exposure to tumor necrosis factor-alpha but not to interleukin-1beta or lipopolysaccharide. The Journal of Biological Chemistry. 274: 28808-15. PMID 10497254 DOI: 10.1074/Jbc.274.40.28808  0.72
1999 Repo H, Harlan JM. Mechanisms and consequences of phagocyte adhesion to endothelium. Annals of Medicine. 31: 156-65. PMID 10442670 DOI: 10.3109/07853899909115974  0.37
1999 Stempien-Otero A, Karsan A, Cornejo CJ, Xiang H, Eunson T, Morrison RS, Kay M, Winn R, Harlan J. Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis. The Journal of Biological Chemistry. 274: 8039-45. PMID 10075703 DOI: 10.1074/Jbc.274.12.8039  0.402
1999 Etzioni A, Doerschuk CM, Harlan JM. Of Man and Mouse: Leukocyte and Endothelial Adhesion Molecule Deficiencies Blood. 94: 3281-3288. DOI: 10.1182/Blood.V94.10.3281.422K37_3281_3288  0.313
1999 Bombeli T, Schwartz BR, Harlan JM. Endothelial Cells Undergoing Apoptosis Become Proadhesive for Nonactivated Platelets Blood. 93: 3831-3838. DOI: 10.1182/Blood.V93.11.3831.411A35_3831_3838  0.358
1998 Zen K, Karsan A, Eunson T, Yee E, Harlan JM. Lipopolysaccharide-induced NF-kappaB activation in human endothelial cells involves degradation of IkappaBalpha but not IkappaBbeta. Experimental Cell Research. 243: 425-33. PMID 9743602 DOI: 10.1006/Excr.1998.4162  0.395
1998 Lorenzon P, Vecile E, Nardon E, Ferrero E, Harlan JM, Tedesco F, Dobrina A. Endothelial cell E- and P-selectin and vascular cell adhesion molecule-1 function as signaling receptors. The Journal of Cell Biology. 142: 1381-91. PMID 9732297 DOI: 10.1083/Jcb.142.5.1381  0.41
1998 Chuang PI, Yee E, Karsan A, Winn RK, Harlan JM. A1 is a constitutive and inducible Bcl-2 homologue in mature human neutrophils. Biochemical and Biophysical Research Communications. 249: 361-5. PMID 9712701 DOI: 10.1006/Bbrc.1998.9155  0.366
1998 Talbott GA, Sharar SR, Paulson JC, Harlan JM, Winn RK. Antibiotic therapy determines subcutaneous Escherichia coli abscess formation after CD18 inhibition in rabbits Journal of Burn Care and Rehabilitation. 19: 284-291. PMID 9710724 DOI: 10.1097/00004630-199807000-00003  0.364
1998 Choi KB, Wong F, Harlan JM, Chaudhary PM, Hood L, Karsan A. Lipopolysaccharide mediates endothelial apoptosis by a FADD-dependent pathway. The Journal of Biological Chemistry. 273: 20185-8. PMID 9685365 DOI: 10.1074/Jbc.273.32.20185  0.433
1998 Karsan A, Cornejo CJ, Winn RK, Schwartz BR, Way W, Lannir N, Gershoni-Baruch R, Etzioni A, Ochs HD, Harlan JM. Leukocyte Adhesion Deficiency Type II is a generalized defect of de novo GDP-fucose biosynthesis. Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium. The Journal of Clinical Investigation. 101: 2438-45. PMID 9616215 DOI: 10.1172/Jci905  0.379
1998 Bombeli T, Schwartz BR, Harlan JM. Adhesion of activated platelets to endothelial cells: evidence for a GPIIbIIIa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin, and GPIbalpha. The Journal of Experimental Medicine. 187: 329-39. PMID 9449713 DOI: 10.1084/Jem.187.3.329  0.366
1998 Hu X, Yee E, Harlan JM, Wong F, Karsan A. Lipopolysaccharide Induces the Antiapoptotic Molecules, A1 and A20, in Microvascular Endothelial Cells Blood. 92: 2759-2765. DOI: 10.1182/Blood.V92.8.2759  0.382
1998 Harlan J. Leukocyte-Mediated Endothelial Injury Journal of Vascular and Interventional Radiology. 9: 675-677. DOI: 10.1016/S1051-0443(98)70352-5  0.355
1997 Winn RK, Ramamoorthy C, Vedder NB, Sharar SR, Harlan JM. Leukocyte-endothelial cell interactions in ischemia-reperfusion injury. Annals of the New York Academy of Sciences. 832: 311-21. PMID 9704059 DOI: 10.1111/J.1749-6632.1997.Tb46259.X  0.336
1997 Karsan A, Harlan JM. Modulation of endothelial cell apoptosis: mechanisms and pathophysiological roles. Journal of Atherosclerosis and Thrombosis. 3: 75-80. PMID 9226458 DOI: 10.5551/Jat1994.3.75  0.373
1997 Cornejo CJ, Winn RK, Harlan JM. Anti-adhesion therapy. Advances in Pharmacology (San Diego, Calif.). 39: 99-142. PMID 9160114 DOI: 10.1016/S1054-3589(08)60070-8  0.368
1997 Ramamoorthy C, Kovarik WD, Winn RK, Harlan JM, Sharar SR. Neutrophil adhesion molecule expression is comparable in perinatal rabbits and humans. Anesthesiology. 86: 420-7. PMID 9054260 DOI: 10.1097/00000542-199702000-00017  0.34
1997 Ramamoorthy C, Sharar SR, Harlan JM, Tedder TF, Winn RK. Blocking L-selectin function attenuates reperfusion injury following hemorrhagic shock in rabbits. The American Journal of Physiology. 271: H1871-7. PMID 8945903 DOI: 10.1152/Ajpheart.1996.271.5.H1871  0.308
1997 Bombeli T, Karsan A, Tait JF, Harlan JM. Apoptotic Vascular Endothelial Cells Become Procoagulant Blood. 89: 2429-2442. DOI: 10.1182/Blood.V89.7.2429  0.439
1997 Thiagarajan RR, Winn RK, Harlan JM. The Role of Leukocyte and Endothelial Adhesion Molecules in Ischemia – Reperfusion Injury Thrombosis and Haemostasis. 78: 310-314. DOI: 10.1055/S-0038-1657545  0.35
1996 Karsan A, Yee E, Harlan JM. Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1. The Journal of Biological Chemistry. 271: 27201-4. PMID 8910286 DOI: 10.1074/Jbc.271.44.27201  0.428
1996 Seki J, Koyama N, Kovach NL, Yednock T, Clowes AW, Harlan JM. Regulation of beta1-integrin function in cultured human vascular smooth muscle cells. Circulation Research. 78: 596-605. PMID 8635217 DOI: 10.1161/01.Res.78.4.596  0.34
1996 Karsan A, Yee E, Kaushansky K, Harlan JM. Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells. Blood. 87: 3089-96. PMID 8605321 DOI: 10.1182/Blood.V87.8.3089.Bloodjournal8783089  0.414
1995 Kling D, Fingerle J, Harlan JM, Lobb RR, Lang F. Mononuclear leukocytes invade rabbit arterial intima during thickening formation via CD18-and VLA-4-dependent mechanisms and stimulate smooth muscle migration. Circulation Research. 77: 1121-8. PMID 7586224 DOI: 10.1161/01.Res.77.6.1121  0.369
1995 Sharar SR, Winn RK, Harlan JM. The adhesion cascade and anti-adhesion therapy: an overview. Springer Seminars in Immunopathology. 16: 359-78. PMID 7570288 DOI: 10.1007/Bf00196093  0.375
1995 McCarty JM, Yee EK, Deisher TA, Harlan JM, Kaushansky K. Interleukin-4 induces endothelial vascular cell adhesion molecule-1 (VCAM-1) by an NF-kappa b-independent mechanism. Febs Letters. 372: 194-8. PMID 7556668 DOI: 10.1016/0014-5793(95)00976-G  0.301
1995 Kovach N, Lin N, Yednock T, Harlan J, Broudy V. Stem cell factor modulates avidity of alpha 4 beta 1 and alpha 5 beta 1 integrins expressed on hematopoietic cell lines Blood. 85: 159-167. DOI: 10.1182/Blood.V85.1.159.Bloodjournal851159  0.394
1994 Bucky LP, Vedder NB, Hong HZ, Ehrlich HP, Winn RK, Harlan JM, May JW. Reduction of burn injury by inhibiting CD18-mediated leukocyte adherence in rabbits. Plastic and Reconstructive Surgery. 93: 1473-80. PMID 7911582 DOI: 10.1097/00006534-199406000-00021  0.345
1994 Winn RK, Paulson JC, Harlan JM. A monoclonal antibody to P-selectin ameliorates injury associated with hemorrhagic shock in rabbits American Journal of Physiology - Heart and Circulatory Physiology. 267. PMID 7528995 DOI: 10.1016/0300-9572(95)94124-R  0.346
1994 McFeely J, Embree L, Harlan J, Albert R. Adhesion to Fibronectin Augments Tumor Necrosis Factor Production by Human Alveolar Macrophages Chest. 105. DOI: 10.1378/Chest.105.3_Supplement.100S  0.302
1994 Mihelcic D, Schleiffenbaum B, Tedder T, Sharar S, Harlan J, Winn R. Inhibition of leukocyte L-selectin function with a monoclonal antibody attenuates reperfusion injury to the rabbit ear Blood. 84: 2322-2328. DOI: 10.1182/Blood.V84.7.2322.Bloodjournal8472322  0.351
1994 Kovach N, Lindgren C, Fefer A, Thompson J, Yednock T, Harlan J. Pentoxifylline inhibits integrin-mediated adherence of interleukin-2- activated human peripheral blood lymphocytes to human umbilical vein endothelial cells, matrix components, and cultured tumor cells Blood. 84: 2234-2242. DOI: 10.1182/blood.v84.7.2234.bloodjournal8472234  0.319
1994 Kovach N, Lindgren C, Fefer A, Thompson J, Yednock T, Harlan J. Pentoxifylline inhibits integrin-mediated adherence of interleukin-2- activated human peripheral blood lymphocytes to human umbilical vein endothelial cells, matrix components, and cultured tumor cells Blood. 84: 2234-2242. DOI: 10.1182/Blood.V84.7.2234.2234  0.427
1994 Price T, Ochs H, Gershoni-Baruch R, Harlan J, Etzioni A. In vivo neutrophil and lymphocyte function studies in a patient with leukocyte adhesion deficiency type II Blood. 84: 1635-1639. DOI: 10.1182/Blood.V84.5.1635.Bloodjournal8451635  0.336
1993 Harlan JM. Leukocyte adhesion deficiency syndrome: insights into the molecular basis of leukocyte emigration. Clinical Immunology and Immunopathology. 67: S16-24. PMID 8500276 DOI: 10.1006/Clin.1993.1079  0.322
1993 Winn RK, Mileski WJ, Kovach NL, Doerschuk CM, Rice CL, Harlan JM. Role of protein synthesis and CD11/CD18 adhesion complex in neutrophil emigration into the lung. Experimental Lung Research. 19: 221-35. PMID 8467763 DOI: 10.3109/01902149309031721  0.372
1993 Deisher TA, Garcia I, Harlan JM. Cytokine-induced adhesion molecule expression on human umbilical vein endothelial cells is not regulated by cyclic adenosine monophosphate accumulation. Life Sciences. 53: 365-70. PMID 8392131 DOI: 10.1016/0024-3205(93)90755-R  0.303
1993 Langdale LA, Flaherty LC, Liggitt HD, Harlan JM, Rice CL, Winn RK. Neutrophils contribute to hepatic ischemia-reperfusion injury by a CD18-independent mechanism. Journal of Leukocyte Biology. 53: 511-7. PMID 8099114 DOI: 10.1002/Jlb.53.5.511  0.326
1993 Winn RK, Liggitt D, Vedder NB, Paulson JC, Harlan JM. Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear Journal of Clinical Investigation. 92: 2042-2047. PMID 7691890 DOI: 10.1172/Jci116799  0.349
1993 Deisher TA, Haddix TL, Montgomery KF, Pohlman TH, Kaushansky K, Harlan JM. The role of protein kinase C in the induction of VCAM-1 expression on human umbilical vein endothelial cells Febs Letters. 331: 285-290. PMID 7690717 DOI: 10.1016/0014-5793(93)80354-W  0.401
1993 O'Brien KD, Allen MD, McDonald TO, Chait A, Harlan JM, Fishbein D, McCarty J, Ferguson M, Hudkins K, Benjamin CD. Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis. The Journal of Clinical Investigation. 92: 945-51. PMID 7688768 DOI: 10.1172/Jci116670  0.354
1993 Deisher TA, Sato TT, Pohlman TH, Harlan JM. A protein kinase C agonist, selective for the beta I isozyme, induces E-selectin and VCAM-1 expression on HUVEC but does not translocate PKC. Biochemical and Biophysical Research Communications. 193: 1283-90. PMID 7686753 DOI: 10.1006/Bbrc.1993.1764  0.393
1993 Kuijpers TW, Mul EP, Blom M, Kovach NL, Gaeta FC, Tollefson V, Elices MJ, Harlan JM. Freezing adhesion molecules in a state of high-avidity binding blocks eosinophil migration. The Journal of Experimental Medicine. 178: 279-84. PMID 7686213 DOI: 10.1084/Jem.178.1.279  0.361
1993 von Andrian UH, Berger EM, Ramezani L, Chambers JD, Ochs HD, Harlan JM, Paulson JC, Etzioni A, Arfors KE. In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes. The Journal of Clinical Investigation. 91: 2893-7. PMID 7685776 DOI: 10.1172/Jci116535  0.409
1993 Alpers CE, Hudkins KL, Davis CL, Marsh CL, Riches W, McCarty JM, Benjamin CD, Carlos TM, Harlan JM, Lobb R. Expression of vascular cell adhesion molecule-1 in kidney allograft rejection. Kidney International. 44: 805-16. PMID 7505038 DOI: 10.1038/Ki.1993.315  0.366
1992 Kovach NL, Carlos TM, Yee E, Harlan JM. A monoclonal antibody to beta 1 integrin (CD29) stimulates VLA-dependent adherence of leukocytes to human umbilical vein endothelial cells and matrix components. The Journal of Cell Biology. 116: 499-509. PMID 1370496 DOI: 10.1083/Jcb.116.2.499  0.384
1991 Bevilacqua M, Butcher E, Furie B, Furie B, Gallatin M, Gimbrone M, Harlan J, Kishimoto K, Lasky L, McEver R, Paulson J, Rosen S, Seed B, Siegelman M, Springer T, et al. Selectins: A family of adhesion receptors Cell. 67: 233-233. PMID 1717161 DOI: 10.1016/0092-8674(91)90174-W  0.318
1991 Montgomery KF, Osborn L, Hession C, Tizard R, Goff D, Vassallo C, Tarr PI, Bomsztyk K, Lobb R, Harlan JM. Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription. Proceedings of the National Academy of Sciences of the United States of America. 88: 6523-7. PMID 1713680 DOI: 10.1073/Pnas.88.15.6523  0.391
1991 Dobrina A, Menegazzi R, Carlos TM, Nardon E, Cramer R, Zacchi T, Harlan JM, Patriarca P. Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor. The Journal of Clinical Investigation. 88: 20-6. PMID 1711540 DOI: 10.1172/Jci115278  0.43
1991 Carlos T, Kovach N, Schwartz B, Rosa M, Newman B, Wayner E, Benjamin C, Osborn L, Lobb R, Harlan J. Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1 Blood. 77: 2266-2271. DOI: 10.1182/Blood.V77.10.2266.2266  0.458
1990 Schwartz BR, Harlan JM. Sulfhydryl reducing agents promote neutrophil adherence without increasing surface expression of CD11b/CD18 (Mac-1, Mo1). Biochemical and Biophysical Research Communications. 165: 51-7. PMID 2574036 DOI: 10.1016/0006-291X(89)91032-2  0.356
1990 Kovach NL, Yee E, Munford RS, Raetz CR, Harlan JM. Lipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo. The Journal of Experimental Medicine. 172: 77-84. PMID 2193101 DOI: 10.1084/Jem.172.1.77  0.339
1990 Carlos TM, Dobrina A, Ross R, Harlan JM. Multiple receptors on human monocytes are involved in adhesion to cultured human endothelial cells. Journal of Leukocyte Biology. 48: 451-6. PMID 1977836 DOI: 10.1002/Jlb.48.5.451  0.416
1990 Vedder NB, Winn RK, Rice CL, Chi EY, Arfors KE, Harlan JM. Inhibition of leukocyte adherence by anti-CD18 monoclonal antibody attenuates reperfusion injury in the rabbit ear. Proceedings of the National Academy of Sciences of the United States of America. 87: 2643-6. PMID 1969637 DOI: 10.1073/Pnas.87.7.2643  0.332
1990 Schwartz BR, Wayner EA, Carlos TM, Ochs HD, Harlan JM. Identification of surface proteins mediating adherence of CD11/CD18-deficient lymphoblastoid cells to cultured human endothelium. The Journal of Clinical Investigation. 85: 2019-22. PMID 1693380 DOI: 10.1172/Jci114668  0.351
1990 Desch C, Dobrina A, Aggarwal B, Harlan J. Tumor necrosis factor-alpha exhibits greater proinflammatory activity than lymphotoxin in vitro Blood. 75: 2030-2034. DOI: 10.1182/Blood.V75.10.2030.2030  0.438
1989 Pohlman TH, Harlan JM. Human endothelial cell response to lipopolysaccharide, interleukin-1, and tumor necrosis factor is regulated by protein synthesis. Cellular Immunology. 119: 41-52. PMID 2784080 DOI: 10.1016/0008-8749(89)90222-0  0.354
1989 Schwartz BR, Harlan JM. Neutrophil membrane sulfhydryl groups are involved in stimulated neutrophil adherence to endothelium. Journal of Leukocyte Biology. 45: 177-82. PMID 2564411 DOI: 10.1002/Jlb.45.3.177  0.374
1989 Toth KM, Harlan JM, Beehler CJ, Berger EM, Parker NB, Linas SL, Repine JE. Dimethylthiourea prevents hydrogen peroxide and neutrophil mediated damage to lung endothelial cells in vitro and disappears in the process. Free Radical Biology & Medicine. 6: 457-66. PMID 2545552 DOI: 10.1016/0891-5849(89)90037-3  0.424
1989 HARLAN JM. Molecular Basis of Leukocyte Adherence to Endothelium in Inflammation The Journal of Japan Atherosclerosis Society. 16: 1105-1107. DOI: 10.5551/Jat1973.16.8_1105  0.3
1988 Vedder NB, Winn RK, Rice CL, Chi EY, Arfors KE, Harlan JM. A monoclonal antibody to the adherence-promoting leukocyte glycoprotein, CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits. The Journal of Clinical Investigation. 81: 939-44. PMID 3278007 DOI: 10.1172/Jci113407  0.325
1988 Vedder NB, Harlan JM. Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium. The Journal of Clinical Investigation. 81: 676-82. PMID 3278004 DOI: 10.1172/Jci113372  0.37
1988 Pohlman TH, Winn RK, Callahan KS, Maier RV, Harlan JM. A glycolipid precursor of bacterial lipopolysaccharide (lipid X) lacks activity against endothelial cells in vitro and is not toxic in vivo. The Journal of Surgical Research. 45: 228-37. PMID 3043110 DOI: 10.1016/0022-4804(88)90069-8  0.313
1987 Pohlman TH, Munford RS, Harlan JM. Deacylated lipopolysaccharide inhibits neutrophil adherence to endothelium induced by lipopolysaccharide in vitro. The Journal of Experimental Medicine. 165: 1393-402. PMID 3572302 DOI: 10.1084/Jem.165.5.1393  0.363
1987 Harlan JM. Neutrophil-mediated vascular injury. Acta Medica Scandinavica. Supplementum. 715: 123-9. PMID 3296674 DOI: 10.1111/J.0954-6820.1987.Tb09912.X  0.328
1987 Chen CS, Thiagarajan P, Schwartz SM, Harlan JM, Heimark RL. The platelet glycoprotein IIb/IIIa-like protein in human endothelial cells promotes adhesion but not initial attachment to extracellular matrix. The Journal of Cell Biology. 105: 1885-92. PMID 2822728 DOI: 10.1083/Jcb.105.4.1885  0.375
1987 Arfors K, Lundberg C, Lindbom L, Lundberg K, Beatty P, Harlan J. A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo Blood. 69: 338-340. DOI: 10.1182/Blood.V69.1.338.Bloodjournal691338  0.348
1986 Gamble JR, Harlan JM, Klebanoff SJ, Vadas MA. Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor. Proceedings of the National Academy of Sciences of the United States of America. 82: 8667-71. PMID 3866246 DOI: 10.1073/Pnas.82.24.8667  0.441
1986 Harlan JM, Thompson PJ, Ross RR, Bowen-Pope DF. Alpha-thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells. The Journal of Cell Biology. 103: 1129-33. PMID 3745265 DOI: 10.1083/Jcb.103.3.1129  0.366
1986 Broudy VC, Kaushansky K, Segal GM, Harlan JM, Adamson JW. Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor. Proceedings of the National Academy of Sciences of the United States of America. 83: 7467-71. PMID 3489939 DOI: 10.1073/Pnas.83.19.7467  0.388
1986 Lopez AF, Williamson DJ, Gamble JR, Begley CG, Harlan JM, Klebanoff SJ, Waltersdorph A, Wong G, Clark SC, Vadas MA. Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. The Journal of Clinical Investigation. 78: 1220-8. PMID 3021817 DOI: 10.1172/Jci112705  0.338
1986 Wallis W, Hickstein D, Schwartz B, June C, Ochs H, Beatty P, Klebanoff S, Harlan J. Monoclonal antibody-defined functional epitopes on the adhesion- promoting glycoprotein complex (CDw18) of human neutrophils Blood. 67: 1007-1013. DOI: 10.1182/Blood.V67.4.1007.Bloodjournal6741007  0.33
1985 Harlan J, Killen P, Senecal F, Schwartz B, Yee E, Taylor R, Beatty P, Price T, Ochs H. The role of neutrophil membrane glycoprotein GP-150 in neutrophil adherence to endothelium in vitro Blood. 66: 167-178. DOI: 10.1182/Blood.V66.1.167.Bloodjournal661167  0.354
1984 Harlan JM, Levine JD, Callahan KS, Schwartz BR, Harker LA. Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide. The Journal of Clinical Investigation. 73: 706-13. PMID 6707200 DOI: 10.1172/Jci111263  0.375
1984 Harker LA, Harlan JM, Ross R. Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons. Circulation Research. 53: 731-9. PMID 6640860 DOI: 10.1161/01.Res.53.6.731  0.381
1984 Harlan JM, Callahan KS. Role of hydrogen peroxide in the neutrophil-mediated release of prostacyclin from cultured endothelial cells. The Journal of Clinical Investigation. 74: 442-8. PMID 6378974 DOI: 10.1172/Jci111440  0.373
1983 Harlan JM, Harker LA, Striker GE, Weaver LJ. Effects of lipopolysaccharide on human endothelial cells in culture. Thrombosis Research. 29: 15-26. PMID 6836543 DOI: 10.1016/0049-3848(83)90121-4  0.414
1982 Harlan JM, Killen PD, Harker LA, Striker GE, Wright DG. Neutrophil-mediated endothelial injury in vitro mechanisms of cell detachment. The Journal of Clinical Investigation. 68: 1394-403. PMID 7033282 DOI: 10.1172/Jci110390  0.441
1980 Wall RT, Harlan JM, Harker LA, Striker GE. Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury Thrombosis Research. 18: 113-121. PMID 7404495 DOI: 10.1016/0049-3848(80)90175-9  0.375
1980 Wall RT, Harlan JM, Harker LA, Striker GE. In vitro effects of hyperlipoproteinemic sera on human endothelium: Inhibition of endothelial cell migration by familial hypercholesterolemic sera Thrombosis Research. 17: 753-765. PMID 7404485 DOI: 10.1016/0049-3848(80)90241-8  0.359
1980 Striker GE, Harlan JM, Schwartz SM. Human endothelial cells in vitro Methods in Cell Biology. 21: 135-151. PMID 6251339 DOI: 10.1016/S0091-679X(08)60763-3  0.383
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