130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Safi F, Dhapola P, Warsi S, Sommarin M, Erlandsson E, Ungerbäck J, Warfvinge R, Sitnicka E, Bryder D, Böiers C, Thakur RK, Karlsson G. Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction. Cell Reports. 42: 113357. PMID 37851570 DOI: 10.1016/j.celrep.2023.113357  0.341
2023 Rundberg Nilsson A, Hidalgo I, Bryder D, Pronk CJ. Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery. Iscience. 26: 106341. PMID 36968066 DOI: 10.1016/j.isci.2023.106341  0.777
2023 Konturek-Ciesla A, Dhapola P, Zhang Q, Säwén P, Wan H, Karlsson G, Bryder D. Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age. Cell Reports. 42: 112304. PMID 36961818 DOI: 10.1016/j.celrep.2023.112304  0.515
2022 Kristiansen TA, Zhang Q, Vergani S, Boldrin E, Krausse N, André O, Nordenfelt P, Sigvardsson M, Bryder D, Ungerbäck J, Yuan J. Developmental cues license megakaryocyte priming in murine hematopoietic stem cells. Blood Advances. PMID 35584393 DOI: 10.1182/bloodadvances.2021006861  0.4
2022 Konturek-Ciesla A, Bryder D. Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and Beyond. Frontiers in Cell and Developmental Biology. 10: 903528. PMID 35573680 DOI: 10.3389/fcell.2022.903528  0.489
2022 Safi F, Dhapola P, Warsi S, Sommarin M, Erlandsson E, Ungerbäck J, Warfvinge R, Sitnicka E, Bryder D, Böiers C, Thakur RK, Karlsson G. Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction. Cell Reports. 39: 110798. PMID 35545037 DOI: 10.1016/j.celrep.2022.110798  0.489
2022 Yuan O, Ugale A, de Marchi T, Anthonydhason V, Konturek-Ciesla A, Wan H, Eldeeb M, Drabe C, Jassinskaja M, Hansson J, Hidalgo I, Velasco-Hernandez T, Cammenga J, Magee JA, Niméus E, ... Bryder D, et al. A somatic mutation in moesin drives progression into acute myeloid leukemia. Science Advances. 8: eabm9987. PMID 35442741 DOI: 10.1126/sciadv.abm9987  0.776
2022 Hidalgo I, Wahlestedt M, Yuan O, Zhang Q, Bryder D, Pronk CJ. Bmi1 induction protects hematopoietic stem cells against pronounced long-term hematopoietic stress. Experimental Hematology. PMID 35192914 DOI: 10.1016/j.exphem.2022.02.004  0.825
2021 Takahashi M, Barile M, Chapple RH, Tseng YJ, Nakada D, Busch K, Fanti AK, Säwén P, Bryder D, Höfer T, Göttgens B. Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics. Stem Cell Reports. PMID 33770496 DOI: 10.1016/j.stemcr.2021.02.020  0.452
2020 Morcos MNF, Zerjatke T, Glauche I, Munz CM, Ge Y, Petzold A, Reinhardt S, Dahl A, Anstee NS, Bogeska R, Milsom MD, Säwén P, Wan H, Bryder D, Roers A, et al. Continuous mitotic activity of primitive hematopoietic stem cells in adult mice. The Journal of Experimental Medicine. 217. PMID 32302400 DOI: 10.1084/Jem.20191284  0.513
2020 Yang W, Trahan GD, Howell ED, Speck NA, Jones KL, Gillen AE, Riemondy K, Hesselberth J, Bryder D, Ernst P. Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis. Stem Cell Reports. PMID 31951812 DOI: 10.1016/J.Stemcr.2019.12.009  0.541
2019 Okeyo-Owuor T, Li Y, Patel RM, Yang W, Casey EB, Cluster AS, Porter SN, Bryder D, Magee JA. The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development. Blood Advances. 3: 2388-2399. PMID 31405949 DOI: 10.1182/Bloodadvances.2019000554  0.385
2019 Singh T, Colberg JK, Sarmiento L, Chaves P, Hansen L, Bsharat S, Cataldo LR, Dudenhöffer-Pfeifer M, Fex M, Bryder D, Holmberg D, Sitnicka E, Cilio C, Prasad RB, Artner I. Loss of MafA and MafB expression promotes islet inflammation. Scientific Reports. 9: 9074. PMID 31235823 DOI: 10.1038/S41598-019-45528-X  0.39
2019 Velasco-Hernandez T, Soneji S, Hidalgo I, Erlandsson E, Cammenga J, Bryder D. Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML. Stem Cell Reports. 12: 112-121. PMID 30595549 DOI: 10.1016/J.Stemcr.2018.11.023  0.434
2019 Canals I, Ginisty A, Quist E, Timmerman R, Fritze J, Miskinyte G, Monni E, Hansen MG, Hidalgo I, Bryder D, Bengzon J, Ahlenius H. Author Correction: Rapid and efficient induction of functional astrocytes from human pluripotent stem cells. Nature Methods. 16: 134. PMID 30514884 DOI: 10.1038/S41592-018-0264-Z  0.342
2019 Dhapola P, Sommarin M, Eldeeb M, Ugale A, Bryder D, Karlsson G. TRANSCRIPTOME BASED PROJECTION OF SINGLE CELLS TO UNCOVER DEVELOPMENT AND HETEROGENEITY OF ABNORMAL HEMATOPOIETIC CELLS Experimental Hematology. 76: S63. DOI: 10.1182/Blood-2019-130587  0.813
2019 Dhapola P, Sommarin M, Eldeeb M, Ugale A, Bryder D, Karlsson G. Transcriptome Based Projection of Single Cells to Uncover Development and Heterogeneity of Abnormal Hematopoietic Cells Blood. 134: 2520-2520. DOI: 10.1182/blood-2019-130587  0.819
2019 Safi F, Krishna Thakur R, Dhapola P, Erlandsoon E, Warsi S, Bryder D, Boiers C, Karlsson G. CD9 Marks Flt3+ Multipotent Hematopoietic Progenitors within Lsk Cells Blood. 134: 2469-2469. DOI: 10.1182/Blood-2019-126758  0.502
2019 Sommarin M, Dhapola P, Geironson Ulfsson L, Safi F, Erlandsson E, Konturek A, Krishna Thakur R, Boiers C, Bryder D, Karlsson G. Immunophenotypic- and Molecular Analysis of Human Hematopoietic Stem and Progenitor Heterogeneity Blood. 134: 3701-3701. DOI: 10.1182/Blood-2019-126407  0.502
2019 Kristiansen TA, Ungerbäck J, Krausse N, Säwen P, Vergani S, Bryder D, Sigvardsson M, Yuan J. 3167 – DEVELOPMENTAL CHANGES IN THE CHROMATIN ACCESSIBILITY OF HEMATOPOIETIC STEM CELLS ARE ASSOCIATED WITH DISTINCT GENETIC PROGRAMS Experimental Hematology. 76: e2. DOI: 10.1016/J.Exphem.2019.09.009  0.509
2019 Ernst P, Bryder D, Jones K, Trahan D, Yang W. AN MLL1-REGULATED RAC/RHO/INTEGRIN SIGNALING AXIS ENHANCES HEMATOPOIESIS FROM EMBRYONIC HEMOGENIC ENDOTHELIAL PRECURSORS Experimental Hematology. 76: S65. DOI: 10.1016/J.Exphem.2019.06.353  0.535
2019 Sommarin M, Dhapola p, Ulfsson LG, Erlandsson E, Konturek a, böiers C, Bryder D, Karlsson G. IMMUNOPHENOTYPIC AND MOLECULAR HETEROGENEITY ANALYSIS OF HUMAN HEMATOPOIETIC STEM AND PROGENITORS Experimental Hematology. 76: S52. DOI: 10.1016/J.Exphem.2019.06.311  0.537
2018 Säwen P, Eldeeb M, Erlandsson E, Kristiansen TA, Laterza C, Kokaia Z, Karlsson G, Yuan J, Soneji S, Mandal PK, Rossi DJ, Bryder D. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging. Elife. 7. PMID 30561324 DOI: 10.7554/Elife.41258  0.75
2018 Canals I, Ginisty A, Quist E, Timmerman R, Fritze J, Miskinyte G, Monni E, Hansen MG, Hidalgo I, Bryder D, Bengzon J, Ahlenius H. Rapid and efficient induction of functional astrocytes from human pluripotent stem cells. Nature Methods. 15: 693-696. PMID 30127505 DOI: 10.1038/S41592-018-0103-2  0.5
2018 Jensen CT, Åhsberg J, Sommarin MNE, Strid T, Somasundaram R, Okuyama K, Ungerbäck J, Kupari J, Airaksinen MS, Lang S, Bryder D, Soneji S, Karlsson G, Sigvardsson M. Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis. The Journal of Experimental Medicine. PMID 29899037 DOI: 10.1084/Jem.20171384  0.443
2018 Davidsson J, Puschmann A, Tedgård U, Bryder D, Nilsson L, Cammenga J. SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies. Leukemia. 32: 1106-1115. PMID 29535429 DOI: 10.1038/S41375-018-0074-4  0.332
2018 Pronk CJH, Bryder D. Immunophenotypic Identification of Early Myeloerythroid Development. Methods in Molecular Biology (Clifton, N.J.). 1678: 301-319. PMID 29071684 DOI: 10.1007/978-1-4939-7346-0_13  0.809
2018 Säwen P, Eldeeb M, Erlandsson E, Kristiansen TA, Laterza C, Kokaia Z, Karlsson G, Yuan J, Soneji S, Mandal PK, Rossi DJ, Bryder D. Author response: Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging Elife. DOI: 10.7554/Elife.41258.018  0.664
2018 Yang W, Ernst P, Bryder D, Jones K. Gain-of-Function MLL1 Model Distinguishes Hematopoietic From Leukemogenic Pathways Experimental Hematology. 64: S111. DOI: 10.1016/J.Exphem.2018.06.179  0.327
2018 Nilsson AR, Bryder D, Pronk C. Tumor Necrosis Factor- Regulates Hematopoietic Stem Cell Activation Experimental Hematology. 64: S99. DOI: 10.1016/J.Exphem.2018.06.136  0.483
2018 Morcos M, Zerjatke T, Glauche I, Anstee N, Bogeska R, Milsom M, Säwén P, Bryder D, Roers A, Gerbaulet A. Mitotic History of Hematopoietic Stem Cells Revisited Experimental Hematology. 64: S88. DOI: 10.1016/J.Exphem.2018.06.101  0.57
2017 Komorowska K, Doyle A, Wahlestedt M, Subramaniam A, Debnath S, Chen J, Soneji S, Van Handel B, Mikkola HKA, Miharada K, Bryder D, Larsson J, Magnusson M. Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration. Cell Reports. 21: 3514-3523. PMID 29262330 DOI: 10.1016/J.Celrep.2017.11.084  0.85
2017 Wahlestedt M, Ladopoulos V, Hidalgo I, Sanchez Castillo M, Hannah R, Säwén P, Wan H, Dudenhöffer-Pfeifer M, Magnusson M, Norddahl GL, Göttgens B, Bryder D. Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor. Cell Reports. 21: 2251-2263. PMID 29166614 DOI: 10.1016/J.Celrep.2017.10.112  0.836
2017 Wahlestedt M, Bryder D. The slippery slope of hematopoietic stem cell aging. Experimental Hematology. PMID 28943295 DOI: 10.1016/J.Exphem.2017.09.008  0.836
2017 Garrison BS, Rybak AP, Beerman I, Heesters B, Mercier FE, Scadden DT, Bryder D, Baron R, Rossi DJ. ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells. Blood. PMID 28615219 DOI: 10.1182/Blood-2016-09-738591  0.766
2017 Wahlestedt M, Erlandsson E, Kristiansen T, Lu R, Brakebusch C, Weissman IL, Yuan J, Martin-Gonzalez J, Bryder D. Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate. Nature Communications. 8: 14533. PMID 28224997 DOI: 10.1038/Ncomms14533  0.85
2017 Tesi B, Davidsson J, Voss M, Rahikkala E, Holmes TD, Chiang SC, Komulainen-Ebrahim J, Gorcenco S, Rundberg Nilsson A, Ripperger T, Kokkonen H, Bryder D, Fioretos T, Henter JI, Möttönen M, et al. Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS and neurological symptoms. Blood. PMID 28202457 DOI: 10.1182/Blood-2016-10-743302  0.747
2017 Elias HK, Bryder D, Park CY. Molecular mechanisms underlying lineage bias in aging hematopoiesis. Seminars in Hematology. 54: 4-11. PMID 28088987 DOI: 10.1053/J.Seminhematol.2016.11.002  0.725
2017 Ugale A, Säwén P, Dudenhöffer-Pfeifer M, Wahlestedt M, Norddahl GL, Bryder D. MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment. Oncogene. 36: 3207-3212. PMID 28068328 DOI: 10.1038/Onc.2016.470  0.822
2017 Jaako P, Ugale A, Wahlestedt M, Velasco-Hernandez T, Cammenga J, Lindström MS, Bryder D. Induction of the 5S RNP-Mdm2-p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia. Leukemia. 31: 213-221. PMID 27256803 DOI: 10.1038/Leu.2016.159  0.775
2017 Dudenhöffer-Pfeifer M, Ugale A, Bryder D. Immunosurveillance during the formation and progression of AML Experimental Hematology. 53: S110. DOI: 10.1016/J.Exphem.2017.06.271  0.765
2017 Säwen P, Bryder D, Mandal P, Rossi D. Hematopoietic stem cells are active contributors to hematopoiesis in steady state Experimental Hematology. 53: S49. DOI: 10.1016/J.Exphem.2017.06.070  0.722
2017 Yuan J, Kristiansen T, Vanhee S, Jaensson-Gyllenbäck E, Zriwil A, Doyle A, Quinn ES, Lang S, Soneji S, Bryder D. Resolving the fetal to adult switch in B lymphopoiesis at the single cell level Experimental Hematology. 53: S32. DOI: 10.1016/J.Exphem.2017.06.025  0.309
2016 Bryder D. Hematopoiesis at single-cell resolution. Blood. 128: 1025-6. PMID 27563143 DOI: 10.1182/Blood-2016-07-726497  0.512
2016 Kristiansen TA, Jaensson Gyllenbäck E, Zriwil A, Björklund T, Daniel JA, Sitnicka E, Soneji S, Bryder D, Yuan J. Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level. Immunity. 45: 346-57. PMID 27533015 DOI: 10.1016/J.Immuni.2016.07.014  0.444
2016 Velasco-Hernandez T, Säwén P, Bryder D, Cammenga J. Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis. Stem Cell Reports. 7: 11-8. PMID 27373927 DOI: 10.1016/J.Stemcr.2016.06.002  0.338
2016 Rundberg Nilsson A, Soneji S, Adolfsson S, Bryder D, Pronk CJ. Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias. Plos One. 11: e0158369. PMID 27368054 DOI: 10.1016/J.Exphem.2016.06.205  0.803
2016 Säwén P, Lang S, Mandal P, Rossi DJ, Soneji S, Bryder D. Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis. Cell Reports. PMID 26997272 DOI: 10.1016/J.Celrep.2016.02.073  0.761
2016 Tesi B, Davidsson J, Voss M, Holmes T, Ripperger T, Chiang S, Nilsson L, Nordenskjöld M, Henter J, Bryder D, Fioretos T, Uusimaa J, Komulainen-Ebrahim J, Möttönen M, Niinimäki R, et al. Cytopenia, Predisposition to Myelodysplastic Syndrome, Immunodeficiency, and Neurological Disease Caused By Gain-of-Function SAMD9L Mutations Is Frequently Ameliorated By Hematopoietic Revertant Mosaicism Blood. 128: 4299-4299. DOI: 10.1182/Blood.V128.22.4299.4299  0.375
2016 Petter S, Mandal PK, Rossi DJ, Bryder D. Hematopoietic Stem Cells Are Active Contributors to Hematopoiesis in Steady State Blood. 128: 421-421. DOI: 10.1182/Blood.V128.22.421.421  0.735
2016 Ugale AS, Adolfsson S, Säwén P, Dudenhöffer-Pfeifer M, Bryder D. Probing Co-Operating Somatic Mutations in MLL-ENL Driven Leukemogenesis Blood. 128: 2855-2855. DOI: 10.1182/Blood.V128.22.2855.2855  0.829
2016 Yang W, Bryder D, Ernst P. Modeling gain-of-function MLL1 to probe HSC self-renewal versus hematologic malignancy Experimental Hematology. 44: S90. DOI: 10.1016/J.Exphem.2016.06.188  0.328
2015 Lang S, Ugale A, Erlandsson E, Karlsson G, Bryder D, Soneji S. SCExV: a webtool for the analysis and visualisation of single cell qRT-PCR data. Bmc Bioinformatics. 16: 320. PMID 26437766 DOI: 10.1186/S12859-015-0757-Z  0.781
2015 Rundberg Nilsson A, Pronk CJ, Bryder D. Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification. Experimental Hematology. 43: 812-7.e1. PMID 26027791 DOI: 10.1016/J.Exphem.2015.05.003  0.8
2015 Jaako P, Debnath S, Olsson K, Zhang Y, Flygare J, Lindström MS, Bryder D, Karlsson S. Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia. Leukemia. 29: 2221-9. PMID 25987256 DOI: 10.1038/Leu.2015.128  0.344
2015 Wahlestedt M, Pronk CJ, Bryder D. Concise review: hematopoietic stem cell aging and the prospects for rejuvenation. Stem Cells Translational Medicine. 4: 186-94. PMID 25548388 DOI: 10.5966/Sctm.2014-0132  0.855
2015 Ugale AS, Adolfsson S, Säwen P, Cammenga J, Bryder D. Probing co-operating somatic mutations in MLL-ENL driven myeloid leukemogenesis Experimental Hematology. 43: S99. DOI: 10.1016/J.Exphem.2015.06.272  0.757
2015 Rundberg Nilsson AJ, Bryder D, Pronk CJ. Hematopoietic stem cell aging in humans associates with functional impairments and an intrinsic megakaryocytic/erythroid bias Experimental Hematology. 43: S91. DOI: 10.1016/J.Exphem.2015.06.239  0.567
2015 Komorowska K, Doyle A, Soneji S, Hultmark S, Bryder D, Mikkola H, Larsson J, Magnusson M. Hepatic leukemia factor is essential for maintaining hematopoietic stem cell function Experimental Hematology. 43: S73. DOI: 10.1016/J.Exphem.2015.06.166  0.545
2014 Mandal PK, Ferreira LM, Collins R, Meissner TB, Boutwell CL, Friesen M, Vrbanac V, Garrison BS, Stortchevoi A, Bryder D, Musunuru K, Brand H, Tager AM, Allen TM, Talkowski ME, et al. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell. 15: 643-52. PMID 25517468 DOI: 10.1016/J.Stem.2014.10.004  0.69
2014 Ugale A, Norddahl GL, Wahlestedt M, Säwén P, Jaako P, Pronk CJ, Soneji S, Cammenga J, Bryder D. Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation. Cell Reports. 9: 1246-55. PMID 25456127 DOI: 10.1016/J.Celrep.2014.10.036  0.834
2014 Velasco-Hernandez T, Hyrenius-Wittsten A, Rehn M, Bryder D, Cammenga J. HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia. Blood. 124: 3597-607. PMID 25267197 DOI: 10.1182/Blood-2014-04-567065  0.446
2014 Wahlestedt M, Bryder D. Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal. Cell Stem Cell. 14: 555-6. PMID 24792111 DOI: 10.1016/J.Stem.2014.04.008  0.837
2014 Wahlestedt M, Ameur A, Moraghebi R, Norddahl GL, Sten G, Woods NB, Bryder D. Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects. Stem Cells (Dayton, Ohio). 32: 1173-82. PMID 24446123 DOI: 10.1002/Stem.1630  0.832
2014 Rundberg Nilsson A, Bryder D, Pronk CJ. Age-Related Alterations in Human Hematopoietic Stem and Progenitor Cells Blood. 124: 5113-5113. DOI: 10.1182/Blood.V124.21.5113.5113  0.558
2014 Wahlestedt M, Säwén P, Ladopoulos V, Norddahl G, Gottgens B, Bryder D. Critical modulation of hematopoietic lineage fate by the PAR/bZIP transcription factor hepatic leukemia factor Experimental Hematology. 42: S64. DOI: 10.1016/J.Exphem.2014.07.246  0.78
2014 Nilsson AR, Bryder D, Pronk C. Age-related alterations in human hematopoietic stem and progenitor cells Experimental Hematology. 42: S58. DOI: 10.1016/j.exphem.2014.07.219  0.494
2013 Rundberg Nilsson A, Bryder D, Pronk CJ. Frequency determination of rare populations by flow cytometry: a hematopoietic stem cell perspective. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 721-7. PMID 23839904 DOI: 10.1002/Cyto.A.22324  0.782
2013 Wahlestedt M, Norddahl GL, Sten G, Ugale A, Frisk MA, Mattsson R, Deierborg T, Sigvardsson M, Bryder D. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. Blood. 121: 4257-64. PMID 23476050 DOI: 10.1182/Blood-2012-11-469080  0.839
2013 Manesso E, Teles J, Bryder D, Peterson C. Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation. Journal of the Royal Society, Interface. 10: 20120817. PMID 23256190 DOI: 10.1098/Rsif.2012.0817  0.43
2013 Hansen N, Ã…gerstam H, Wahlestedt M, Landberg N, Askmyr M, Ehinger M, Rissler M, Lilljebjörn H, Johnels P, Ishiko J, Melo JV, Alexander WS, Bryder D, JärÃ¥s M, Fioretos T. SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function. Leukemia. 27: 130-5. PMID 22824785 DOI: 10.1038/Leu.2012.169  0.833
2013 Velasco T, Norddahl G, Hyrenius A, Yang Y, Bryder D, Cammenga J. Role of HIF-1α in leukemia initiating cells in acute myeloid leukemia Experimental Hematology. 41: S47. DOI: 10.1016/J.Exphem.2013.05.184  0.681
2013 Nilsson AR, Bryder D, Pronk C. The value of sorted murine hematopoietic stem cells in serial transplantation experiments - a transgenic mouse model example Experimental Hematology. 41: S38. DOI: 10.1016/J.Exphem.2013.05.152  0.511
2012 Norddahl GL, Wahlestedt M, Gisler S, Sigvardsson M, Bryder D. Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function. Aging Cell. 11: 1128-31. PMID 22809070 DOI: 10.1111/J.1474-9726.2012.00863.X  0.838
2011 Jaako P, Flygare J, Olsson K, Quere R, Ehinger M, Henson A, Ellis S, Schambach A, Baum C, Richter J, Larsson J, Bryder D, Karlsson S. Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia. Blood. 118: 6087-96. PMID 21989989 DOI: 10.1182/Blood-2011-08-371963  0.409
2011 Welinder E, Mansson R, Mercer EM, Bryder D, Sigvardsson M, Murre C. The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor. Proceedings of the National Academy of Sciences of the United States of America. 108: 17402-7. PMID 21972416 DOI: 10.1073/Pnas.1111766108  0.441
2011 Pronk CJ, Veiby OP, Bryder D, Jacobsen SE. Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors. The Journal of Experimental Medicine. 208: 1563-70. PMID 21768269 DOI: 10.1084/Jem.20110752  0.503
2011 Norddahl GL, Pronk CJ, Wahlestedt M, Sten G, Nygren JM, Ugale A, Sigvardsson M, Bryder D. Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. Cell Stem Cell. 8: 499-510. PMID 21549326 DOI: 10.1016/J.Stem.2011.03.009  0.837
2011 Pronk CJ, Bryder D. Flow cytometry-based identification of immature myeloerythroid development. Methods in Molecular Biology (Clifton, N.J.). 699: 275-93. PMID 21116988 DOI: 10.1007/978-1-61737-950-5_13  0.79
2011 Karlsson S, Flygare J, Jaako P, Bryder D. Diamond-Blackfan Anemia: Erythropoiesis Lost in Ribosome Biosynthesis Blood. 118: SCI-2-SCI-2. DOI: 10.1182/Blood.V118.21.Sci-2.Sci-2  0.448
2011 Hansen N, Agerstam H, Wahlestedt M, Ehinger M, Johnels P, Ishiko J, Melo JV, Alexander WS, Bryder D, Järås M, Fioretos T. Socs2 Is Dispensable for BCR/ABL1-Induced Chronic Myeloid Leukemia-Like Disease in Mice and for Normal Hematopoietic Stem Cell Function, Blood. 118: 3743-3743. DOI: 10.1182/Blood.V118.21.3743.3743  0.826
2011 Norddahl GL, Wahlestedt M, Gisler S, Sigvardsson M, Bryder D. Enhanced Cytokine Responsiveness Counteracts Age-Induced Decline in Hematopoietic Stem Cell Function Blood. 118: 2342-2342. DOI: 10.1182/Blood.V118.21.2342.2342  0.835
2010 Zandi S, Bryder D, Sigvardsson M. Load and lock: the molecular mechanisms of B-lymphocyte commitment. Immunological Reviews. 238: 47-62. PMID 20969584 DOI: 10.1111/J.1600-065X.2010.00950.X  0.462
2010 Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, Rossi DJ. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proceedings of the National Academy of Sciences of the United States of America. 107: 5465-70. PMID 20304793 DOI: 10.1073/Pnas.1000834107  0.836
2010 Bryder D, Sigvardsson M. Shaping up a lineage--lessons from B lymphopoesis. Current Opinion in Immunology. 22: 148-53. PMID 20207528 DOI: 10.1016/J.Coi.2010.02.001  0.458
2010 Zetterblad J, Qian H, Zandi S, Månsson R, Lagergren A, Hansson F, Bryder D, Paulsson N, Sigvardsson M. Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication. Bmc Genomics. 11: 108. PMID 20152025 DOI: 10.1186/1471-2164-11-108  0.474
2010 Mansson R, Zandi S, Welinder E, Tsapogas P, Sakaguchi N, Bryder D, Sigvardsson M. Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity. Blood. 115: 2601-9. PMID 19996414 DOI: 10.1182/Blood-2009-08-236398  0.502
2010 Jaako P, Flygare J, Olsson K, Quere R, Larsson J, Bryder D, Karlsson S. Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond-Blackfan Anemia Blood. 116: 193-193. DOI: 10.1182/Blood.V116.21.193.193  0.536
2009 Bhattacharya D, Czechowicz A, Ooi AG, Rossi DJ, Bryder D, Weissman IL. Niche recycling through division-independent egress of hematopoietic stem cells. The Journal of Experimental Medicine. 206: 2837-50. PMID 19887396 DOI: 10.1182/Blood.V114.22.79.79  0.838
2009 Bereshchenko O, Mancini E, Moore S, Bilbao D, Månsson R, Luc S, Grover A, Jacobsen SE, Bryder D, Nerlov C. Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML. Cancer Cell. 16: 390-400. PMID 19878871 DOI: 10.1016/J.Ccr.2009.09.036  0.475
2009 Attema JL, Pronk CJ, Norddahl GL, Nygren JM, Bryder D. Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence. Oncogene. 28: 2238-43. PMID 19398954 DOI: 10.1038/Onc.2009.94  0.778
2009 Jaako P, Flygare J, Olsson K, Schambach A, Baum C, Larsson J, Bryder D, Karlsson S. A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E / Proerythroblast Transition. Blood. 114: 178-178. DOI: 10.1182/Blood.V114.22.178.178  0.439
2008 Nygren JM, Bryder D. A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal. Plos One. 3: e3710. PMID 19002266 DOI: 10.1371/Journal.Pone.0003710  0.552
2008 Zandi S, Mansson R, Tsapogas P, Zetterblad J, Bryder D, Sigvardsson M. EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors. Journal of Immunology (Baltimore, Md. : 1950). 181: 3364-72. PMID 18714008 DOI: 10.4049/Jimmunol.181.5.3364  0.402
2008 Mansson R, Zandi S, Anderson K, Martensson IL, Jacobsen SE, Bryder D, Sigvardsson M. B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells. Blood. 112: 1048-55. PMID 18495958 DOI: 10.1182/Blood-2007-11-125385  0.393
2008 Weischenfeldt J, Damgaard I, Bryder D, Theilgaard-Mönch K, Thoren LA, Nielsen FC, Jacobsen SE, Nerlov C, Porse BT. NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements. Genes & Development. 22: 1381-96. PMID 18483223 DOI: 10.1101/Gad.468808  0.527
2008 Pronk CJ, Attema J, Rossi DJ, Sigvardsson M, Bryder D. Deciphering developmental stages of adult myelopoiesis. Cell Cycle (Georgetown, Tex.). 7: 706-13. PMID 18461720 DOI: 10.4161/Cc.7.6.5565  0.836
2008 Thorén LA, Liuba K, Bryder D, Nygren JM, Jensen CT, Qian H, Antonchuk J, Jacobsen SE. Kit regulates maintenance of quiescent hematopoietic stem cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 2045-53. PMID 18250409 DOI: 10.4049/Jimmunol.180.4.2045  0.543
2007 Pronk CJ, Rossi DJ, MÃ¥nsson R, Attema JL, Norddahl GL, Chan CK, Sigvardsson M, Weissman IL, Bryder D. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell. 1: 428-42. PMID 18371379 DOI: 10.1016/J.Stem.2007.07.005  0.847
2007 Rossi DJ, Seita J, Czechowicz A, Bhattacharya D, Bryder D, Weissman IL. Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle (Georgetown, Tex.). 6: 2371-6. PMID 17700071 DOI: 10.4161/Cc.6.19.4759  0.836
2007 Moody JL, Singbrant S, Karlsson G, Blank U, Aspling M, Flygare J, Bryder D, Karlsson S. Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development. Stem Cells (Dayton, Ohio). 25: 2809-19. PMID 17673527 DOI: 10.1634/Stemcells.2006-0602  0.552
2007 Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 447: 725-9. PMID 17554309 DOI: 10.1038/Nature05862  0.849
2007 Lagergren A, Månsson R, Zetterblad J, Smith E, Basta B, Bryder D, Akerblad P, Sigvardsson M. The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells. The Journal of Biological Chemistry. 282: 14454-62. PMID 17374609 DOI: 10.1074/Jbc.M610263200  0.485
2007 Rossi DJ, Bryder D, Weissman IL. Hematopoietic stem cell aging: mechanism and consequence. Experimental Gerontology. 42: 385-90. PMID 17275237 DOI: 10.1016/J.Exger.2006.11.019  0.794
2007 Serafini M, Dylla SJ, Oki M, Heremans Y, Tolar J, Jiang Y, Buckley SM, Pelacho B, Burns TC, Frommer S, Rossi DJ, Bryder D, Panoskaltsis-Mortari A, O'Shaughnessy MJ, Nelson-Holte M, et al. Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells. The Journal of Experimental Medicine. 204: 129-39. PMID 17227908 DOI: 10.1084/Jem.20061115  0.773
2007 Weischenfeldt J, Damgaard I, Bryder D, Nerlov C, Porse B. Nonsense-Mediated mRNA Decay Is Essential for the Hematopietic Compartement. Blood. 110: 506-506. DOI: 10.1182/Blood.V110.11.506.506  0.444
2006 Warren L, Bryder D, Weissman IL, Quake SR. Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR Proceedings of the National Academy of Sciences of the United States of America. 103: 17807-17812. PMID 17098862 DOI: 10.1073/Pnas.0608512103  0.563
2006 Bryder D, Rossi DJ, Weissman IL. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. The American Journal of Pathology. 169: 338-46. PMID 16877336 DOI: 10.2353/Ajpath.2006.060312  0.774
2006 Nygren JM, Bryder D, Jacobsen SE. Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property. Journal of Immunology (Baltimore, Md. : 1950). 177: 201-8. PMID 16785515 DOI: 10.4049/Jimmunol.177.1.201  0.465
2006 Bhattacharya D, Bryder D, Rossi DJ, Weissman IL. Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors. Cell Cycle (Georgetown, Tex.). 5: 1135-9. PMID 16760650 DOI: 10.4161/Cc.5.11.2772  0.794
2006 Bhattacharya D, Rossi DJ, Bryder D, Weissman IL. Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning. The Journal of Experimental Medicine. 203: 73-85. PMID 16380511 DOI: 10.1084/Jem.20051714  0.804
2005 Porse BT, Bryder D, Theilgaard-Mönch K, Hasemann MS, Anderson K, Damgaard I, Jacobsen SE, Nerlov C. Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage. The Journal of Experimental Medicine. 202: 85-96. PMID 15983063 DOI: 10.1084/Jem.20050067  0.478
2005 Rossi DJ, Bryder D, Zahn JM, Ahlenius H, Sonu R, Wagers AJ, Weissman IL. Cell intrinsic alterations underlie hematopoietic stem cell aging. Proceedings of the National Academy of Sciences of the United States of America. 102: 9194-9. PMID 15967997 DOI: 10.1073/Pnas.0503280102  0.838
2005 Adolfsson J, Månsson R, Buza-Vidas N, Hultquist A, Liuba K, Jensen CT, Bryder D, Yang L, Borge OJ, Thoren LA, Anderson K, Sitnicka E, Sasaki Y, Sigvardsson M, Jacobsen SE. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell. 121: 295-306. PMID 15851035 DOI: 10.1016/J.Cell.2005.02.013  0.54
2005 Yang L, Dybedal I, Bryder D, Nilsson L, Sitnicka E, Sasaki Y, Jacobsen SE. IFN-gamma negatively modulates self-renewal of repopulating human hemopoietic stem cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 752-7. PMID 15634895 DOI: 10.4049/Jimmunol.174.2.752  0.464
2005 Yang L, Bryder D, Adolfsson J, Nygren J, Månsson R, Sigvardsson M, Jacobsen SE. Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood. 105: 2717-23. PMID 15572596 DOI: 10.1182/Blood-2004-06-2159  0.545
2005 Bryder D, Björgvinsdóttir H, Sasaki Y, Jacobsen SE. Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion. The Journal of Gene Medicine. 7: 137-44. PMID 15538726 DOI: 10.1002/Jgm.658  0.535
2004 Bryder D, Sasaki Y, Borge OJ, Jacobsen SE. Deceptive multilineage reconstitution analysis of mice transplanted with hemopoietic stem cells, and implications for assessment of stem cell numbers and lineage potentials. Journal of Immunology (Baltimore, Md. : 1950). 172: 1548-52. PMID 14734733 DOI: 10.4049/Jimmunol.172.3.1548  0.566
2004 Yang L, Aolfsson J, Månsson R, Bryder D, Borge O, Thoren L, Sitnicka E, Sasaki Y, Sigvardsson M, Jacobsen SEW. A Novel Road Map for Blood Lineage Commitment and Development: Identification of a Lympho-Myeloid Stem/Progenitor Cell Lacking Erythro-Megakaryocytic Potential. Blood. 104: 2790-2790. DOI: 10.1182/Blood.V104.11.2790.2790  0.588
2004 Hultquist A, Mansson R, Sigvardsson M, Adolfsson J, Bryder D, Yang L, Thoren L, Jacobsen SE. Genetic Evidence of a Novel Blood Differentiation Pathway from Lympho-Myeloid Hematopoietic Stem/Progenitor Cells, Independent of Common Myeloid Progenitors. Blood. 104: 1696-1696. DOI: 10.1182/Blood.V104.11.1696.1696  0.545
2003 Sitnicka E, Brakebusch C, Martensson IL, Svensson M, Agace WW, Sigvardsson M, Buza-Vidas N, Bryder D, Cilio CM, Ahlenius H, Maraskovsky E, Peschon JJ, Jacobsen SE. Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis. The Journal of Experimental Medicine. 198: 1495-506. PMID 14610045 DOI: 10.1084/Jem.20031152  0.352
2003 Dybedal I, Yang L, Bryder D, Aastrand-Grundstrom I, Leandersson K, Jacobsen SE. Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression. Blood. 102: 118-26. PMID 12637333 DOI: 10.1182/Blood-2002-07-2286  0.553
2002 Sitnicka E, Bryder D, Theilgaard-Mönch K, Buza-Vidas N, Adolfsson J, Jacobsen SE. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. Immunity. 17: 463-72. PMID 12387740 DOI: 10.1016/S1074-7613(02)00419-3  0.53
2002 Nilsson L, Astrand-Grundström I, Anderson K, Arvidsson I, Hokland P, Bryder D, Kjeldsen L, Johansson B, Hellström-Lindberg E, Hast R, Jacobsen SE. Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8. Blood. 100: 259-67. PMID 12070035 DOI: 10.1182/Blood-2001-12-0188  0.358
2002 Björgvinsdóttir H, Bryder D, Sitnicka E, Ramsfjell V, De Jong I, Olsson K, Rusterholz C, Karlsson S, Jacobsen SE. Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach. Human Gene Therapy. 13: 1061-73. PMID 12067439 DOI: 10.1089/104303402753812467  0.451
2001 Adolfsson J, Borge OJ, Bryder D, Theilgaard-Mönch K, Astrand-Grundström I, Sitnicka E, Sasaki Y, Jacobsen SE. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity. 15: 659-69. PMID 11672547 DOI: 10.1016/S1074-7613(01)00220-5  0.495
2001 Bryder D, Ramsfjell V, Dybedal I, Theilgaard-Mönch K, Högerkorp CM, Adolfsson J, Borge OJ, Jacobsen SE. Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation. The Journal of Experimental Medicine. 194: 941-52. PMID 11581316 DOI: 10.1084/Jem.194.7.941  0.514
2001 Dybedal I, Bryder D, Fossum A, Rusten LS, Jacobsen SE. Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells. Blood. 98: 1782-91. PMID 11535512 DOI: 10.1182/Blood.V98.6.1782  0.492
2000 Bryder D, Jacobsen SEW. Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro Blood. 96: 1748-1755. DOI: 10.1182/Blood.V96.5.1748  0.406
1999 Ramsfjell V, Bryder D, Björgvinsdóttir H, Kornfält S, Nilsson L, Borge OJ, Jacobsen SE. Distinct Requirements for Optimal Growth and In Vitro Expansion of Human CD34+CD38− Bone Marrow Long-Term Culture-Initiating Cells (LTC-IC), Extended LTC-IC, and Murine In Vivo Long-Term Reconstituting Stem Cells Blood. 94: 4093-4102. DOI: 10.1182/Blood.V94.12.4093.424K09_4093_4102  0.331
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