Thomas A. Steitz

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
Biochemistry, structural chemistry
Website:
https://www.nobelprize.org/prizes/chemistry/2009/steitz/biographical/
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"Thomas A. Steitz"
Bio:

(1940 - 2018)
http://www.nasonline.org/member-directory/deceased-members/8586.html
https://history.aip.org/phn/11811001.html
http://medicine.yale.edu/mbb/faculty/thomas_steitz.profile
http://www.chem.yale.edu/faculty/steitz.html
http://www.yale.edu/steitz/
The Nobel Prize in Chemistry 2009 was awarded jointly to Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath "for studies of the structure and function of the ribosome".

Cross-listing: Chemistry Tree - Crystallography Tree

Parents

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Laszlo Lorand research assistant 1960-1960 Northwestern (Chemistry Tree)
 (Kinetic study of the hydrolysis of a variety of para-nitrophenyl ester substrate analogues by chymotrypsin, trypsin and thrombin.)
William N. Lipscomb grad student 1966 Harvard (Chemistry Tree)
David M. Blow post-doc 1967-1970 MRC-LMB (Chemistry Tree)

Children

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John J. Perona grad student Yale (Chemistry Tree)
Timothy J. Richmond grad student 1975 Yale (Chemistry Tree)
Adrian Goldman grad student 1980-1985 Yale (Chemistry Tree)
Phoebe A. Rice grad student 1992 Yale (Chemistry Tree)
David Jeruzalmi grad student 1994 Yale (Chemistry Tree)
Chad A. Brautigam grad student 1997 Yale (Chemistry Tree)
Daniel L. Kaplan grad student 2000 Yale (Chemistry Tree)
Andres E. Leschziner grad student 2000 Yale
Matthew C. Franklin grad student 2001 Yale (Chemistry Tree)
Huiming Li grad student 2001 Yale (Chemistry Tree)
Min Lu grad student 2001 Yale (Chemistry Tree)
Kakoli Mitra grad student 2001 Yale (Chemistry Tree)
Fang Li grad student 2002 Yale (Chemistry Tree)
Bo-Lu Zhou grad student 2002 Yale (Chemistry Tree)
Daniel Joseph Klein grad student 2004 Yale (Chemistry Tree)
Weikai Li grad student 2004 Yale (Chemistry Tree)
T. Martin Schmeing grad student 2004 Yale (Chemistry Tree)
Daqi Tu grad student 2005 Yale (Chemistry Tree)
Jennifer M. Kavran grad student 2006 Yale (Chemistry Tree)
Andrea J. Berman grad student 2001-2007 Yale (Chemistry Tree)
Kimberly J. Durniak grad student 2008 Yale (Chemistry Tree)
Hitesh Sharma grad student 2009 Yale (Chemistry Tree)
Robin E. Stanley grad student 2009 Yale (Chemistry Tree)
Richard A. Wing grad student 2010 Yale (Chemistry Tree)
David Bulkley grad student 2013 Yale (Chemistry Tree)
Raktim N Roy grad student 2014-2019 Yale (Chemistry Tree)
Robert J. Fletterick post-doc Yale (Chemistry Tree)
Wekai Li post-doc Yale (Cell Biology Tree)
Steve C. Schultz post-doc Yale (Evolution Tree)
Bin Liu post-doc 2008- Yale (Chemistry Tree)
David Bruce McKay post-doc 1978-1982 Yale (Chemistry Tree)
Lorena S. Beese post-doc 1986-1992 Yale (Chemistry Tree)
Wei Yang post-doc 1992-1995 Yale (Chemistry Tree)
Soo Hyun Eom post-doc 1994-1997 Yale (Chemistry Tree)
Jeffrey Lewis Hansen post-doc 2003 Yale (Evolution Tree)
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Publications

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Zuo Y, De S, Feng Y, et al. (2020) Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience. 23: 101445
Lomakin IB, De S, Wang J, et al. (2020) Crystal structure of the C-terminal domain of DENR. Computational and Structural Biotechnology Journal. 18: 696-704
Joseph NN, Roy RN, Steitz TA. (2020) Molecular dynamics analysis of Mg -dependent cleavage of a pistol ribozyme reveals a fail-safe secondary ion for catalysis. Journal of Computational Chemistry
Lomakin IB, Dmitriev SE, Steitz TA. (2018) Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation. Proceedings of the National Academy of Sciences of the United States of America
Lin J, Zhou D, Steitz TA, et al. (2018) Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design. Annual Review of Biochemistry
Liu B, Hong C, Huang RK, et al. (2017) Structural basis of bacterial transcription activation. Science (New York, N.Y.). 358: 947-951
Vaidya AT, Lomakin IB, Joseph NN, et al. (2017) Crystal Structure of the C-terminal Domain of Human eIF2D and its Implications on Eukaryotic Translation Initiation. Journal of Molecular Biology
Lomakin IB, Stolboushkina EA, Vaidya AT, et al. (2017) Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Reports. 20: 521-528
Nguyen LA, Wang J, Steitz TA. (2017) Crystal structure of Pistol, a class of self-cleaving ribozyme. Proceedings of the National Academy of Sciences of the United States of America
Liu B, Steitz TA. (2016) Structural insights into NusG regulating transcription elongation. Nucleic Acids Research
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